Digital Commons Network^™

Electronic Structure Based Classification Of Neurotransmitters And Related Drugs, Amrita Jha

Theses and Dissertations

A fundamental understanding of the relationship between structure and activity of neurotransmitters in the human brain is of vital importance for the design targeted drugs. Using density functional theory and hybrid exchange correlation energy functionals we have studied the structure-activity-relationships of some important neurotransmitters and selected drugs by calculating their absolute hardness (η) and absolute electronegativity (χ). A plot of the η- χ diagram allowed us to assign them into three distinct groups, namely, (i) Acetylcholine analogs (positively charged structure), (ii) GABA analogs (zwitterionic structures) and (iii) monoamines. The results suggest that brain stem is chemically soft because of distribution …

October 6, 2010 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Undergraduate Curriculum And Academic Policy Committee Minutes, October 6, 13, 20, And 27, 2010

Undergraduate Curriculum and Academic Policy Committee Minutes

Minutes from the Wright State University Faculty Senate Undergraduate Curriculum and Academic Policy Committee meetings held on October 6, 13, 20, and 27, 2010.

Mapping Water Collisions For Interstellar Space Conditions, C.-H. Yang, G. Sarma, J. J. Ter Meulen, D. H. Parker, George C. Mcbane, Laurent Wiesenfeld, A. Faure

Peer Reviewed Articles

We report a joint experimental and theoretical study that directly tests the quality of the potential energy surfaces used to calculate energy changing cross sections of water in collision with helium and molecular hydrogen, at conditions relevant for astrophysics. Fully state-to-state differential cross sections are measured for H₂O-He and H₂O-H₂ collisions at 429 and 575 cm^-1 collision energy, respectively. We compare these differential cross sections with theoretical ones for H₂O+H₂ derived from state-of-the-art potential energy surfaces [P. Valiron et al., J. Chem. Phys. 129, 134306 (2008)] and quantum scattering …

The Antelope, University Of Nebraska At Kearney

The Antelope

No abstract provided.

Structural Control - Purdue University, Jake R. Carlson

Data Curation Profiles Directory

The researcher interviewed for this data curation profile is an earthquake engineer who is studying devices that can reduce the response of buildings during earthquakes. Specifically, the objective of this project is to develop design methodologies that are suitable for structures that have control devices in them. She uses a method called “real-time hybrid testing” to validate the performance of the design methodologies and their dampers. The overall goal is to create a mathematical model for the magnetorheological damper whose results can be compared with results from physical tests. The data management needs concern refitting the data into the NEES …

Take Pride In America In Southern Nevada: Quarterly Progress Report, Period Covering October 5, 2010 – January 4, 2010, Margaret N. Rees

Anti-littering Programs

• The Hector’s Helpers program with the Clark County School District continued curriculum development.
• The team was selected to serve on the litter and recycling work group for Keep Las Vegas Beautiful.
• The team continued to develop the GIS database.
• A total of 12 clean-up events were conducted this quarter.

Simulation Of Groundwater Flow And Effects Of Groundwater Irrigation On Stream Base Flow In The Elkhorn And Loup River Basins, Nebraska, 1895-2055: Phase Two, Jennifer S. Stanton, Steven M. Peterson, Michael N. Fienen

United States Geological Survey: Water Reports and Publications

Regional groundwater-flow simulations for a 30,000-square-mile area of the High Plains aquifer, referred to collectively as the Elkhorn-Loup Model, were developed to predict the effects of groundwater irrigation on stream base flow in the Elkhorn and Loup River Basins, Nebraska. Simulations described the stream-aquifer system from predevelopment through 2005 [including predevelopment (pre-1895), early development (1895–1940), and historical development (1940 through 2005) conditions] and future hypothetical development conditions (2006 through 2033 or 2055). Predicted changes to stream base flow that resulted from simulated changes to groundwater irrigation will aid development of long-term strategies for management of hydrologically connected water supplies.

The …

Instabilities And Oscillations In Isotropic Active Gels, Shiladitya Banerjee, M. Cristina Marchetti

Physics - All Scholarship

We present a generic formulation of the continuum elasticity of an isotropic crosslinked active gel. The gel is described by a two-component model consisting of an elastic network coupled frictionally to a permeating fluid. Activity is induced by active crosslinkers that undergo an ATP-activated cycle and transmit forces to the network. The on/off dynamics of the active crosslinkers is described via rate equations for unbound and bound motors. For large activity motors yield a contractile instability of the network. At smaller values of activity, the on/off motor dynamics provides an effective inertial drag on the network that opposes elastic restoring …

Magic, Monsters, And Merlin: An Exploration Of The Fantasy Genre In A Fifth Grade Setting, Traci Bowles

Theses and Dissertations

The purposes of this exploratory investigation were to determine how fantasy literature helps children explore, process, and discuss real world issues and topics and what other applications the genre had in the classroom. This study was conducted by implementing a genre study in a fifth grade classroom. Seventeen students participated in the research model. Data collected included audiotaped discussions, student projects and artifacts, and my personal teacher research journal. The data was analyzed recursively across all data sets to determine patterns and themes. Data was coded according to the four main patterns and counted across data sets. If the pattern …

2010 October 5, Faculty Senate Minutes, State Univerity Of New York College At Cortland

Minutes

Faculty Senate Minutes No. 3, October 5, 2010

Handling External Events Efficiently In Gillespie's Stochastic Simulation Algorithm, Brad Geltz

Theses and Dissertations

Gillespie's Stochastic Simulation Algorithm (SSA) provides an elegant simulation approach for simulating models composed of coupled chemical reactions. Although this approach can be used to describe a wide variety biological, chemical, and ecological systems, often systems have external behaviors that are difficult or impossible to characterize using chemical reactions alone. This work extends the applicability of the SSA by adding mechanisms for the inclusion of external events and external triggers. We define events as changes that occur in the system at a specified time while triggers are defined as changes that occur to the system when a particular condition is …

Molecular Mechanisms Of Persistence Of Mutualistic Bacteria Photorhabdus In The Entomopathogenic Nematode Host, Ruisheng An, Parwinder Grewal

School of Earth, Environmental, & Marine Sciences Faculty Publications

Symbioses between microbes and animals are ubiquitous, yet little is known about the intricate mechanisms maintaining such associations. In an emerging mutualistic model system, insect-pathogenic bacteria Photorhabdus and their insect-parasitic nematode partner Heterorhabditis, we found that the bacteria undergo major transcriptional reshaping in the nematode intestine. Besides general starvation mechanisms, the bacteria induce cellular acidification to slow down growth, switch to pentose phosphate pathway to overcome oxidative stress and nutrition limitation, and shed motility but develop biofilm to persist in the nematode intestine until being released into the insect hemolymph. These findings demonstrate how the symbiotic bacteria reduce their …

Time Series Analysis As Input For Predictive Modeling: Predicting Cardiac Arrest In A Pediatric Intensive Care Unit, Curtis Kennedy

Dissertations and Theses (Open Access)

The first manuscript, entitled "Time-Series Analysis as Input for Clinical Predictive Modeling: Modeling Cardiac Arrest in a Pediatric ICU" lays out the theoretical background for the project. There are several core concepts presented in this paper. First, traditional multivariate models (where each variable is represented by only one value) provide single point-in-time snapshots of patient status: they are incapable of characterizing deterioration. Since deterioration is consistently identified as a precursor to cardiac arrests, we maintain that the traditional multivariate paradigm is insufficient for predicting arrests. We identify time series analysis as a method capable of characterizing deterioration in an objective, …

October 4, 2010, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Data Basics For Research., Elizabeth Karoly Mba, Steve Milinchuk

Department of Community Health and Health Studies

No abstract provided.

First Year Investigation Of Gravity Waves And Temperature Variability Over The Andes, Jonathan Pugmire, Neal R. Criddle, Michael J. Taylor, Dominique Pautet, Yucheng Zhao

Graduate Student Presentations

The Andes region is an excellent natural laboratory for investigating gravity wave influences on the Upper Mesospheric and Lower Thermospheric (MLT) dynamics: during the summer months the dominant gravity waves result from deep convection arising from severe thunderstorms over the continent to the east. In winter this convective activity is expected to be replaced by strong orographic forcing due to intense prevailing zonal winds blowing eastward from the Pacific Ocean and suddenly encountering the towering Andes mountain range (6000m). This creates large amplitude mountain waves that have been measured well into the stratosphere and most recently penetrate occasionally into the …

Current, October 04, 2010, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

Faculty Senate Agenda, October 4, 2010, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Educational Policies Committee Report
• Honors Program Report
• Library Advisory Council Report
• Parking Committee Report
• EPC Items
• ADVS's Proposal for a Doctor of Veterinary Medicine degree
• Summer School Calendar
• PRPC Section 402.3 - 402.9 The Faculty Senate and Its Committees

Ferroelectricity In Non-Stoichiometric Srtio3 Films Studied By Ultraviolet Raman Spectroscopy, Dmitri A. Tenne, A. K. Farrar

Physics Faculty Publications and Presentations

Homoepitaxial Sr_1+xTiO_3+δ films with -0.2 ≤ x ≤ 0.25 grown by reactive molecular-beam epitaxy on SrTiO₃ (001) substrates have been studied by ultraviolet Raman spectroscopy. Non-stoichiometry for strontium- deficient compositions leads to the appearance of strong first-order Raman scattering at low temperatures, which decreases with increasing temperature and disappears at about 350 K. This indicates the appearance of a spontaneous polarization with a paraelectric-to-ferroelectric transition temperature above room temperature. Strontium-rich samples also show a strong first-order Raman signal, but the peaks are significantly broader and exhibit a less pronounced temperature dependence, indicating a stronger contribution …

Take Pride In America In Southern Nevada: Quarterly Progress Report, Period Covering July 5, 2010 – October 4, 2010, Margaret N. Rees

Anti-littering Programs

• The street team portion of the media campaign was completed.
• The Hector’s Helpers program with the Clark County School District continued curriculum development.
• The team was selected to serve on the litter and recycling work group for Keep Las Vegas Beautiful.
• The team continued to develop the GIS database.
• A total of five clean-up events were conducted this quarter.

Monitor Newsletter October 04, 2010, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff

The Collegian (2010-10-04), Christine Cavazos

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 63, No. 7

Dynamic Oryza Genomes: Repetitive Dna Sequences As Genome Modeling Agents, Navdeep Gill, Phillip Sanmiguel, Braham Deep Singh Dhillon, Brian Abernathy, Hyeran Kim, Lincoln Stein, Doreen Ware, Rod Wing, Scott A. Jackson

Biology Faculty Articles

Repetitive sequences, primarily transposable elements form an indispensable part of eukaryotic genomes. However, little is known about how these sequences originate, evolve and function in context of a genome. In an attempt to address this question, we performed a comparative analysis of repetitive DNA sequences in the genus Oryza, representing ~15 million years of evolution. Both Class I and Class II transposable elements, through their expansion, loss and movement in the genome, were found to influence genome size variation in this genus. We identified 38 LTRretrotransposon families that are present in 1,500 or more copies throughout Oryza, and many are …

Statistical Mμsings, Fall 2010, Statistics Department

Statistics Department Newsletter

No abstract provided.

Star - Science Teacher And Researcher Program, Science Teacher And Researcher Program

STAR Program Research Presentations

The Science Teacher and Researcher (STAR) program provides pre-service and early career science and math teachers with paid summer internships in national, independent, and university laboratories thereby allowing participants to pursue a prestigious dual "teacher-researcher" career path. With the guidance of a research mentor, STAR Fellows work on original science projects for 8 to 10 weeks. Weekly education workshops and an opening and closing conference provide context and opportunities for STAR Fellows to consider how the "doing of science" may be translated into the "teaching of science." At the closing conference STAR Fellows present their research in a poster session …

Engineering Advantage, Fall 2010, College Of Engineering

Engineering Advantage

No abstract provided.

Infobrief Enrollment (Census) - Fall 2010, Office Of Institutional Planning & Analysis

Office of Institutional Research

The InfoBrief is a publication that takes a very brief look at enrollment and is published every quarter after census.

Fall 2010 Fact Book, Office Of Institutional Planning & Analysis

Office of Institutional Research

The Fact Book is an annual comprehensive publication of historical trend data on admissions, enrollment, degrees awarded, faculty/staff data, and financial aid.

A Relational Political Science, Scott D. Mcclurg, Joseph K. Young

Working Papers

No abstract provided.