Digital Commons Network^™

Molecular Evidence For A Functional Ecdysone Signaling System In Brugia Malayi, George Tzertzinis, Ana L. Egaña, Subba Reddy Palli, Marc Robinson-Rechavi, Chris R. Gissendanner, Canhui Liu, Thomas R. Unnasch, Claude V. Maina

Entomology Faculty Publications

BACKGROUND: Filarial nematodes, including Brugia malayi, the causative agent of lymphatic filariasis, undergo molting in both arthropod and mammalian hosts to complete their life cycles. An understanding of how these parasites cross developmental checkpoints may reveal potential targets for intervention. Pharmacological evidence suggests that ecdysteroids play a role in parasitic nematode molting and fertility although their specific function remains unknown. In insects, ecdysone triggers molting through the activation of the ecdysone receptor: a heterodimer of EcR (ecdysone receptor) and USP (Ultraspiracle).

METHODS AND FINDINGS: We report the cloning and characterization of a B. malayi EcR homologue (Bma-EcR). Bma-EcR dimerizes with …

New Approaches To Preventing, Diagnosing, And Treating Neonatal Sepsis, Karen Edmond, Anita K. M. Zaidi

Department of Paediatrics and Child Health

No abstract provided.

The Collegian (2010-03-08), Julianna Sosa

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 62, No. 22

Latent Tuberculosis Among Pregnant Mothers In A Resource Poor Setting In Northern Tanzania: A Cross-Sectional Study, Faheem G. Sheriff, Karim P. Manji, Mohamed P. Manji, Mohamedsuhel M. Chagani, Rose M. Mpembeni, Ahmed Jusabani, Zaheerabbas A. Alwani

Faculty of Health Sciences, East Africa

Background:

Untreated latent TB infection (LTBI) is a significant risk factor for active pulmonary tuberculosis, hence predisposing to adverse pregnancy outcomes and mother to child transmission. The prevalence of latent tuberculosis in pregnancy and its association, if any, with various socio-demographic, obstetric and clinical characteristics was evaluated.

Methods:

Northern Tanzania was chosen as the study site. In a cross-sectional study, a total of 286 pregnant women from 12 weeks gestational age to term were assessed. Screening was undertaken using an algorithm involving tuberculin skin testing, symptom screening in the form of a questionnaire, sputum testing for acid fast bacilli followed …

Role Of All Of The Prrsv Glycoproteins In Protective Immune Response, Asit K. Pattnaik

School of Veterinary and Biomedical Sciences: Faculty Publications

Porcine reproductive and respiratory syndrome virus (PRRSV) contains the major glycoprotein, GP5, as well as three other minor glycoproteins, namely, GP2a, GP3, and GP4, on the virion envelope, all of which are required for generation of infectious virions. To study their interactions amongst each other and with the cellular receptor for PRRSV, we have cloned each of the viral glycoproteins and CD163 receptor in expression vectors and examined their expression and interaction with each other in transfected cells by co-immunoprecipitation (co-IP) assay using monospecific antibodies. Our results show that strong interaction exists between GP4 and GP5 proteins, although weak interactions …

Adverse Outcome Pathways And Ecological Risk Assessment: Bridging To Population-Level Effects, Vincent J. Kramer, Matthew A. Etterson, Markus Hecker, Cheryl A. Murphy, Guritno Roesijadi, Daniel J. Spade, Julann A. Spromberg, Magnus Wang, Gerald T. Ankley

United States Environmental Protection Agency: Publications

Maintaining the viability of populations of plants and animals is a key focus for environmental regulation. Population-level responses integrate the cumulative effects of chemical stressors on individuals as those individuals interact with and are affected by their conspecifics, competitors, predators, prey, habitat, and other biotic and abiotic factors. Models of population-level effects of contaminants can integrate information from lower levels of biological organization and feed that information into higher-level community and ecosystem models. As individual-level endpoints are used to predict population responses, this requires that biological responses at lower levels of organization be translated into a form that is usable …

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

Changing Po2licy: The Elements For Improving Childhood Asthma Outcomes, Anne Rossier Markus, Meagan Lyon, Sara J. Rosenbaum

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

Childhood asthma is a serious and chronic health issue that affects one in seven U.S. children and their families, compromising their health and quality of life and placing a heavy financial burden on families as well as an enormous strain on the health care system. Treating, managing, and ultimately preventing and reducing the burden of asthma represents a critical test of the ability of the U.S. health system – health insurers, clinical care providers, and public health agencies – to work together. Our investigation found that, as a country, we already know enough to act and improve life for the …

Changing Policy: The Elements For Improving Childhood Asthma Outcomes, Anne R. Markus, Meagan Lyon, Sara J. Rosenbaum

Health Policy and Management Faculty Publications

This report lays out the facts and offers specific policy recommendations for success that could change the face of childhood asthma in America. These recommendations aim to make better use of programs and policies already in place, such as Medicaid and the Children's Health Insurance Program (CHIP), as well as private sector insurance coverage and existing public health programs. The recommendations also underscore the importance of careful research -- scientific, practical, and community-based -- in order to continue to learn what works best and strengthen knowledge for future action. In a reformed health system, these initial efforts are not wasted …

Using National Border Climate Adjustment Schemes To Facilitate Global Greenhouse Gas Management In Industrial Production, Alexandra Khrebtukova

Washington and Lee Journal of Energy, Climate, and the Environment

I argue that an appropriately conceived and well-designed border climate adjustment scheme, as a policy mechanism potentially utilizable by many States party to the United Nations Framework Convention on Climate Change, may lead to desirable consequences for the development of comprehensive global greenhouse gas management in furtherance of the Framework Convention’s objectives. By creating the conditions for a healthy experimentalism and regulatory competition among the regulating bodies of diverse national markets, the use of origin-neutral border climate adjustment schemes, equivalent to the climate regulatory costs imposed on like domestic products as a condition of market access, may lead to a …

Risk Factors For Endometritis After Low Transverse Cesarean Delivery, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Preetishma Devkota, Victoria J. Fraser

Infectious Diseases Faculty Publications

No abstract provided.

Attributable Costs Of Surgical Site Infection And Endometritis After Low Transverse Cesarean Delivery, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Barton H. Hamilton, Victoria J. Fraser

Infectious Diseases Faculty Publications

No abstract provided.

What's Happening: March, 2010, Maine Medical Center

What's Happening

No abstract provided.

Epidemiologic Investigation Of Immune-Mediated Polyradiculoneuropathy Among Abattoir Workers Exposed To Porcine Brain, Stacy M. Holzbauer, Aaron S. Devries, James J. Sejvar, Christine H. Lees, Jennifer Adjemian, Jennifer H. Mcquiston, Carlota Medus, Catherine A. Lexau, Julie R. Harris, Sergio E. Recuenco, Ermias D. Belay, James F. Howell, Bryan F. Buss, Mady Homig, John D. Gibbins, Scott E. Brueck, Kirk E. Smith, Richard N. Danila, W. Ian Lipkin, Daniel H. Lachance, P. James. B. Dyck, Ruth Lynfield

United States Public Health Resources

Background: In October 2007, a cluster of patients experiencing a novel polyradiculoneuropathy was identified at a pork abattoir (Plant A). Patients worked in the primary carcass processing area (warm room); the majority processed severed heads (head-table). An investigation was initiated to determine risk factors for illness.

Methods and Results: Symptoms of the reported patients were unlike previously described occupational associated illnesses. A case-control study was conducted at Plant A. A case was defined as evidence of symptoms of peripheral neuropathy and compatible electrodiagnostic testing in a pork abattoir worker. Two control groups were used - randomly selected non-ill warm-room workers …

Antimicrobial Activity Of A Rarely Known Species, Morinda Citrifolia L., R. Usha, Sangeetha Sashidharan, M. Palaniswamy

Ethnobotanical Leaflets

Morinda Citrifolia is one of the most important traditional Polynesian medicinal plants. This small evergreen tree is native from South Eastern Asia to Australia and now it has a Pantropical distribution. It has antifungal, antibacterial, antiinflammatory and antiviral activities. Morinda citrifolia L. was studied for its antimicrobial activity. The leaves of this plant were dried, powdered and different extracts were prepared using different solvents like benzene, chloroform, ethyl acetate, ethanol and water. Four organisms, namely E.coli, Staphylococcus aureus, Candida albicans and Aspergillus niger, were used for investigation. The activity of each solvent extract was checked on each organism by disc …

Conceptions Regarding Children’S Health: An Examination Of Ethnotheories In A Sending And Receiving Community, Maria Rosario De Guzman, Jennifer Deleon, Gloria Gonzalez-Kruger, Rodrigo Cantarero

Department of Child, Youth, and Family Studies: Faculty Publications

Ethnotheories are beliefs that adults hold about children and the factors that impact upon their development. Scholars suggest that “ethnotheories” serve as cultural models that underlie motivations for parenting practices and the way adults organize children’s early experiences. This study examines Mexican adults’ ethnotheories about children’s health in two communities that are linked by transnational migrants and serve as sending and receiving communities for workers. Forty-four Mexican adults in six focus groups discussed well-being issues affecting children in their communities. Qualitative analyses using grounded theory revealed a complex conception of children’s health issues that included physical, psychological, and behavioral components …

Population, Sex Ratios And Development In Greenland, Lawrence C. Hamilton, Rasmos Ole Rasmussen

Sociology

Abstract

During the 20th century, Greenland society experienced a dramatic transformation from scattered settlements based on hunting, with mostly turf dwellings, to an urbanizing post-industrial economy. This transformation compressed socioeconomic development that took centuries to millennia elsewhere into a few generations. The incomplete demographic transition that accompanied this development broadly followed the classical pattern, but with distinctive variations relating to Greenland's Arctic environment, sparse population, and historical interactions between two cultures: an indigenous Inuit majority and an influential Danish minority. One heritage from Danish colonial administration, and continued more recently under Greenland Home Rule, has been the maintenance of population …

Draft Of Utah Division Of Wildlife Resources Statewide Management Plan For Elk

Aspen Bibliography

No abstract provided.

Phytochemical Screening Of Methanolic Extract And Antibacterial Activity Of Active Principles Of Hepatoprotective Herb, Eclipta Alba, Sunita Dalal, Sudhir K. Kataria, K. V. Sastry, Svs Rana

Ethnobotanical Leaflets

Aerial parts of Eclipta alba are used traditionally for the treatment of several diseases of liver, skin and stomach. Methanolic extract and active principle compound of a well known Indian hepatoprotective herb, Eclipta alba was tested for in vitro antimicrobial studies. It was evaluated using zone of inhibition studies and minimum inhibitory concentration. The extract exhibited activity against all six strains studied. Phytochemical screening of the extract revealed the presence of tannins, flavonoids, coumestans, saponins and alkaloids etc. Ethylacetate fraction and further pure isolated wedelolactone showed enhanced antimicrobial activity. Staphylococcus epidermidis, Staphylococcus aureus and Salmonella typhimurium were most susceptible. Shigella …

Oncolog Volume 55, Number 03, March 2010, Bryan Tutt, Joe Munch

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Benign Tumors That Cause Big Problems:Fortunately, parathyroid tumors can be removed with minimally invasive surgery.
• Preventing Bone Loss nad Fractures in Cancer Patients
• INBRIEF: Leukemia Cells Observed Burning Fat to Evade Death/Assesment Tool Takes Aim at Graft-versus-Host Disease
• House call: Immunotherapy:Boosting the Body's Fight Against Cancer

Combating Antimicrobial Resistance: Regulatory Strategies And Institutional Capacity, William M. Sage, David A. Hyman

Faculty Scholarship

Amnesia is a common, important, but rarely noted side effect of antibiotics. Apart from medical historians, few recall the severe morbidity and mortality once associated with acute bacterial infection. However, decades of antibiotic overuse and misuse have compromised the long-term availability and efficacy of these life-saving therapies. If designed and implemented appropriately, regulation can reduce the risk of bacterial infection, reserve antibiotics for circumstances where they are necessary, and rationalize the use of the most powerful agents. Regulation of antibiotic resistance can be justified, and should be guided, by both efficiency and fairness. A range of regulatory options are available--some …

Needle Stick Injuries Among Health Care Workers Of Public Sector Tertiary Care Hospitals Of Karachi, Mubashir Aslam, Tahir Taj, Arif Ali, Waseem Mirza, Hammad Ali, Mudassir Iqbal Dar, Nasira Badar

Community Health Sciences

OBJECTIVE: To estimate the frequency of needle stick injuries (NSI) among health care workers (nurses, student nurses and paramedical staff) in public hospitals of Karachi.STUDY DESIGN: Cross sectional, observational.PLACE AND DURATION OF STUDY: This study was conducted in three public tertiary care hospitals of Karachi, from November 2007 to January 2008.METHODOLOGY: Data was collected by structured interview-based questionnaires in Urdu and English language. Questionnaire was designed to obtain information regarding demography, work experience, hepatitis vaccination status, and occurrence of needle stick injuries with associated factors. Needle stick injury that occurred in the previous month was the defined outcome. Data was …

Climate Change And Human Health Consequences, Jennifer Alford

Social Sciences

The intent of this project is to highlight the human health ramifications of climate change and the strategies for coping with this challenge. Possible effects may include reduction in agricultural outputs, dwindling freshwater aquifers, intensification of tropospheric ozone, and expanding areas of disease-carrying vectors. Because humans are closely connected with their environment, we are directly affected by any environmental disturbance. Consequently, human health is vulnerable to the effects of climate change. The questions are: what are those consequences, how will we adapt, and what does the future hold?

Tuberculosis Awareness And Public Opinion On Expanding Health Insurance Coverage, Belal A. Saadeh Phd, Msn, Rn

Dissertations

This quantitative descriptive cross-sectional study examined the effect of TB awareness and demographic variables on the level of support for expanding health insurance coverage for all residents, including undocumented immigrants. A modified 13-item tool developed by Morisky et al. (1990) was used to measure TB awareness; a single item created by the researcher assessed personal opinion regarding expansion of health insurance coverage; and a demographic questionnaire was used to collect data from 281 registered voters in San Diego County. The majority of San Diego County voters participating in the study supported at least some expansion of health insurance coverage. ANOVA …

Testicular Schistosomiasis, Saeed M. Al-Qahtani, Stephane J. Droupy

Saudi Medical Journal

Testicular schistosomiasis is extremely rare, with only 12 cases reported. Reaching the diagnosis for this lesion that mimics malignant tumor is a great dilemma for the radiologist as well as the urologist. We report a case of testicular schistosomiasis from France that was managed conservatively. A 31- year-old Egyptian male presented to the outpatient clinic with primary infertility for 9 years. Physical examination revealed healthy male without any congenital malformations. Blood count and C-reactive protein level were normal. Hormonal tests were normal. Scrotal ultrasound showed small mass at the right testis. Scrotal exploration was carried out and frozen section results …

Diabetic Profile Of Pakistani Pilgrims In Makkah During Hajj Season 2007-2008, Muhammad A. Sharif, Asad Mahmood, Javed-Ur Rehman, Kaswar S. Ansari, Sajid Munir

Saudi Medical Journal

No abstract provided.

City Of San Luis Obispo: Community And Municipal Operations 2005 Baseline Greenhouse Gas Emissions Inventory, Geoffrey M. Chiapella

Master's Theses

The passage of AB 32 in 2006 initiated the need for city planners in California to consider the quantification of greenhouse gas emissions at the community level in order to develop policies and programs to reduce emissions in the future. Although local jurisdictions are not required to quantify and report emissions at this time, the AB 32 Climate Change Scoping Plan recommended a reduction goal for local governments of 15 percent below today’s levels by 2020 to ensure consistent reduction goals at the state and local levels.

ICLEI-Local Governments for Sustainability initiated the Cities for Climate Protection (CCP) campaign in …

March 2010 Newsletter, Career Center, Illinois Wesleyan University

Career Connections Newsletter

Issue Highlights:

• Following Your Dream is the Art Decision
• Alumni Profile of Erin Anderson, Class 2007: Medicinal Chemist/Future PhD
• Get Professional with LinkedIn

Bjc Today

BJC Today

No abstract provided.

Faktor - Faktor Yang Berhubungan Dengan Kepatuhan Petugas Terhadap Sop Imunisasi Pada Penanganan Vaksin Campak, Dini Yulianti, Anhari Achadi

Kesmas

Campak adalah penyakit yang sangat menular dan menjadi salah satu penyebab utama kematian anak di negara berkembang termasuk Indonesia. Imunisasi campak di Indonesia telah berhasil dilaksanakan dengan baik, tetapi ternyata masih banyak ditemukan kasus campak di beberapa daerah. Salah satu faktor yang diduga menjadi penyebabnya adalah daya guna vaksin yang tidak maksimal karena sistem rantai vaksin yang sangat menentukan untuk pengamanan mutu vaksin tidak berfungsi dengan baik atau para petugas imunisasi tidak melakukan penanganan vaksin sesuai dengan prosedur yang telah ditentukan. Berdasarkan atas kenyataan ini, dilakukan penelitian mengenai faktor-faktor yang berhubungan kepatuhan petugas imunisasi terhadap SOP (Standard Operating Procedure) imunisasi …