Digital Commons Network^™

Conserved Genes Act As Modifiers Of Invertebrate Smn Loss Of Function Defects, Maria Dimitriadi, James N. Sleigh, Amy Walker, Howard C. Chang, Anindya Sen, Geetika Kalloo, Jevede Harris, Tom Barsby, Melissa B. Walsh, John S. Satterlee, Chris Li, David Van Vactor, Spyros Artavanis-Tsakonas, Anne C. Hart

Publications and Research

Spinal Muscular Atrophy (SMA) is caused by diminished function of the Survival of Motor Neuron (SMN) protein, but the molecular pathways critical for SMA pathology remain elusive. We have used genetic approaches in invertebrate models to identify conserved SMN loss of function modifier genes. Drosophila melanogaster and Caenorhabditis elegans each have a single gene encoding a protein orthologous to human SMN; diminished function of these invertebrate genes causes lethality and neuromuscular defects. To find genes that modulate SMN function defects across species, two approaches were used. First, a genome-wide RNAi screen for C. elegans SMN modifier genes was undertaken, yielding …

The Scarlet - Volume Xci, No. 6 (October 28, 2010), Scarlet Staff

The Scarlet Archive (Student Newspaper) (1939-2011) (In Progress)

The October 28, 2010 edition of The Scarlet (est. 1939), Clark University's student-run newspaper. The Scarlet is intellectually and editorially independent of the University.

The cover story for this issue is "Reflections of perception and time: Artists Tim Murdoch and Heidi Kayser talk about their new exhibit at Clark". Other headlines include "Making the grade? Clark gets B+ on 2011 College Sustainability Report Card", "CUSC [Clark Undergraduate Student Council] looks into SAF [Student Activities Fund] issues", "The media's latest martyr: NPR fires Juan Williams" a review of the film Red starring Bruce Willis, and "Tradition meets innovation: Beats Antiques rocks …

In Drag On Drugs, Ibpp Editor

International Bulletin of Political Psychology

Since commentators generally assert that the war on illegal and illicit drugs has been a failure, we should evaluate the assertion and, then, opine on why there is a war, winnable or not.

The Missouri Miner, October 28, 2010

The Missouri Miner Newspaper

No abstract provided.

The Comment, October 28, 2010, Bridgewater State University

The Comment

No abstract provided.

The Advocate, October 28, 2010, Minnesota State University Moorhead

The Advocate

No abstract provided.

Usa V. Daaniyal Muhammad

2010 Decisions

USDC for the Eastern District of Pennsylvania

Usa V. James Hall

2010 Decisions

USDC for the Western District of Pennsylvania

Exponent, Vol. 42, Iss. 8, 2010-10-28, University Of Alabama In Huntsville

2010

No abstract provided.

A Map Of Human Genome Variation From Population-Scale Sequencing, David L. Altshuler, Richard M. Durbin, Gonçalo R. Abecasis, David R. Bentley, Aravinda Chakravarti, Andrew G. Clark, Francis S. Collins, Francisco M. De La Vega, Peter Donnelly, Michael Egholm, Paul Flicek, Stacey B. Gabriel, Richard A. Gibbs, Bartha M. Knoppers, Eric S. Lander, Hans Lehrach, Elaine R. Mardis, Gil A. Mcvean, Debbie A. Nickerson, Leena Peltonen, Alan J. Schafer, Stephen T. Sherry, Jun Wang, Richard K. Wilson, David Deiros, Mike Metzker, Donna Muzny, Jeff Reid, David Wheeler, Shenzhen Jun Wang, Jingxiang Li, Min Jian, Guoqing Li, Ruiqiang Li

Faculty Publications

The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation as a foundation for investigating the relationship between genotype and phenotype. Here we present results of the pilot phase of the project, designed to develop and compare different strategies for genome-wide sequencing with high-throughput platforms. We undertook three projects: low-coverage whole-genome sequencing of 179 individuals from four populations; high-coverage sequencing of two mother-father-child trios; and exon-targeted sequencing of 697 individuals from seven populations. We describe the location, allele frequency and local haplotype structure of approximately 15 million single nucleotide polymorphisms, 1 million short insertions and …

2010 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Jennie Jones

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Jennie Jones was the guest speaker at the reception.

Bulletin, Dmacc Marketing

Bulletin

No abstract provided.

Daily Eastern News: October 28, 2010, Eastern Illinois University

October

No abstract provided.

The Grizzly, October 28, 2010, Katie Callahan, Joshua C. Walsh, Sara Hourwitz, Michael Delaney, Lisa Jobe, Danielle Chmelewski, Kate Kehoe, Elisa Diprinzio, Sarah Bollert, Traci Johnson, Stephen Hayman, Greta Martikainen-Watcke, Jessica Orbon, Sara Sherr

Ursinus College Grizzly Newspaper, 1978 to Present

Junot Diaz Speaks to Ursinus Campus • Berman Celebrates 20th Anniversary with Open House • Active Minds Talks About Mental Illness • Ursinus Music Department Active on Campus • UC Homecoming 2010 • Senior Explores Middle East • Students Celebrate Writing • Internship Spotlight: Jason Ward • Finally, Ursinus Creates an Arena for Race Relations • Once Upon a Potty • Letter to the Editor • Hey UC, Give Me a [Fall] Break • Bears Travel in Packs During Cross Country Season • Women's Rugby Takes on Scranton This Saturday

A Single-Chip Ultra-Wideband Based Wireless Sensor Network Node, Nathan R. Schemm

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

This dissertation presents the design of a next-generation wireless sensor network node. The node incorporates many new and innovative technologies such as an ultra-wideband radio which allows very low-energy communication, a low-power radiation detection front end, and an efficient implementation of dynamic voltage scaling which improves the energy efficiency of the integrated processor. The complete design is integrated on a single chip for maximum power savings and minimal size.

The ultra-wideband transceiver includes many novel techniques to produce a receiver with low power consumption and fast and accurate packet acquisition and reception. These include the use of a standard symmetric …

Montana Kaimin, October 28, 2010, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

The Weekly Challenger, October 28, 2010, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The October 28, 2010, issue of The Weekly Challenger.

Mustang Daily, October 28, 2010

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Retention And Loss Of Rna Interference Pathways In Trypanosomatid Protozoans, Lon-Fye Lye, Katherine Owens, Huafang Shi, Silvane M. F. Murta, Ana Carolina Vieira, Salvatore J. Turco, Christian Tschudi, Elisabetta Ullu, Stephen M. Beverley

Molecular and Cellular Biochemistry Faculty Publications

RNA interference (RNAi) pathways are widespread in metaozoans but the genes required show variable occurrence or activity in eukaryotic microbes, including many pathogens. While some Leishmania lack RNAi activity and Argonaute or Dicer genes, we show that Leishmania braziliensis and other species within the Leishmania subgenus Viannia elaborate active RNAi machinery. Strong attenuation of expression from a variety of reporter and endogenous genes was seen. As expected, RNAi knockdowns of the sole Argonaute gene implicated this protein in RNAi. The potential for functional genetics was established by testing RNAi knockdown lines lacking the paraflagellar rod, a key component of the …

Central Florida Future, Vol. 42 No. 67, October 28, 2010

Central Florida Future

UCF receives four grants; Cutting down distractions; Drivers' Safety; Police make room for new station, offices; Local band duals as students, musicians.

Hawks' Herald -- October 28, 2010, Roger Williams University

Hawk's Herald

No abstract provided.

The George-Anne, Georgia Southern University

The George-Anne

• Autumn Music Performance to be Absurd
• News
• Views
• Weekend Wrap
• Features
• Reviews
• Classifieds
• Sports

The Bg News October 28, 2010, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. October 28, 2010. Volume 101-Issue 47.

The Cowl - V. 75 - N. 7 - Oct 28, 2010

The Cowl

The Cowl - student newspaper of Providence College. Volume 75 - Number 7 - October 28, 2010. 36 pages.

The Eastern Echo, October 28, 2010, Eastern Michigan University

EMU Student Newspaper: The Normal News & The Eastern Echo

No abstract provided.

Vista: October 28, 2010, University Of San Diego

USD Vista (1965-)

No abstract provided.

Spectrum, Volume 27, Issue 6, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights Include: Make Your Vote Count for Midterm Elections -- Volunteers Help Bridgeport 'Feel the Warmth' -- Seattle University Strives to Save Environment -- Editorials -- Dance Team 'Jumps on It' -- A Day in the Life: Sacred Heart Ice Hockey

Otter Realm, October 28, 2010, California State University, Monterey Bay

The Otter Realm

AS & OSU Students Helping Students Get the Best Out of College -- You Otter Be Doing Oct.28 - Nov. 10 --For Unlawful Carnal Knowledge -- The Dharma of the Dalai Lama -- Save the Rainforests & Breathe Easier -- Students Promote "End The War Rally" -- Signed With an X: Poets Speak about Immigration -- Cal Sate Monterey Attends Ethics Conference -- You Otter Have a Safe Halloween! -- Santa Cruz Politics: Prepare for Trick or Treat -- Staff of the Issue: Steven Levinson -- Student of the Issue: Rheann Fall -- AS vs. OSU Whose running the show? …

Quaker Campus, October 28, 2010 (Vol. 97, Issue 8), Whittier College

Quaker Campus

No abstract provided.

Lanthorn, Vol. 45, No. 19, October 28, 2010, Grand Valley State University

Volume 45, July 8, 2010 - June 9, 2011

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.