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Alcohol Problems In Young Adults Transitioning From Adolescence To Adulthood: The Association With Race And Gender, Karen G. Chartier, Michie N. Hesselbrock, Victor M. Hesselbrock

Social Work Publications

Race and gender may be important considerations for recognizing alcohol related problems in Black and White young adults. This study examined the prevalence and age of onset of individual alcohol problems and alcohol problem severity across race and gender subgroups from a longitudinal study of a community sample of adolescents followed into young adulthood (N = 166; 23–29 yrs. old who were drinkers). All alcohol problems examined first occurred when subjects were in their late teens and early 20s. Drinking in hazardous situations, blackouts, and tolerance were the most common reported alcohol problems. In race and gender comparisons, more …

Multiple Independent Loci At Chromosome 15q25.1 Affect Smoking Quantity: A Meta-Analysis And Comparison With Lung Cancer And Copd, Nancy L. Saccone, Robert C. Culverhouse, Tae-Hwi Schwantes-An, Dale S. Cannon, Xiangning Chen, Sven Cichon, Ina Giegling, Shizhong Han, Younghun Han, Kaisu Keskitalo-Vuokko, Xiangyang Kong, Maria T. Landi, Jennie Z. Ma, Susan E. Short, Sarah H. Stephens, Victoria L. Stevens, Lingwei Sun, Yufei Wang, Angela S. Wenzlaff, Steven H. Aggen, Naomi Breslau, Peter Broderick, Nilanjan Chatterjee, Jingchun Chen, Andrew C. Heath, Marku Heliovaara, Nicole R. Hoft, David J. Hunter, Majken K. Jensen, Nicholas G. Martin, Grant W. Montgomery, Tianhua Niu, Thomas J. Payne, Leena Peltonen, Michele L. Pergadia, John P. Rice, Richard Sherva, Margaret R. Spitz, Juzhong Sun, Jen C. Wang, Robert B. Weiss, William Wheeler, Stephanie H. Witt, Bao-Zhu Yang, Neil E. Caporaso, Marissa A. Ehringer, Tim Eisen, Susan M. Gapstur, Joel Gelemter, Richard Houlston, Jaakko Kaprio, Kenneth S. Kendler, Peter Kraft, Mark F. Leppert, Ming D. Li, Pamela A. F. Madden, Markus M. Nothen, Sreekumar Pillai, Marcella Rietschel, Dan Rujescu, Ann Schwartz, Christopher I. Amos, Laura J. Bierut

Psychiatry Publications

Recently, genetic association findings for nicotine dependence, smoking behavior, and smoking-related diseases converged to implicate the chromosome 15q25.1 region, which includes the CHRNA5-CHRNA3-CHRNB4 cholinergic nicotinic receptor subunit genes. In particular, association with the nonsynonymous CHRNA5 SNP rs16969968 and correlates has been replicated in several independent studies. Extensive genotyping of this region has suggested additional statistically distinct signals for nicotine dependence, tagged by rs578776 and rs588765. One goal of the Consortium for the Genetic Analysis of Smoking Phenotypes (CGASP) is to elucidate the associations among these markers and dichotomous smoking quantity (heavy versus light smoking), lung cancer, and chronic obstructive pulmonary …

Menorah Review (No. 73, Summer/Fall, 2010)

Menorah Review

An Interpretation of the Valley of Bones (Ezekiel 37:1-14) -- Books in Brief: New and Notable -- Hebrew: A World of Its Own -- How an Educated Elite May Have Shaped the Bible -- Moreshet: From the Classics -- Saul Bellow to Cynthia Ozick on the Holocaust -- Speaking Otherwise: Form and Meaning in the Book of Ruth -- Two Poems

Berberine Inhibits Hiv Protease Inhibitor-Induced Inflammatory Response By Modulating Er Stress Signaling Pathways In Murine Macrophages, Weibin Zha, Guang Liang, Jian Xiao, Elaine Studer, Phillip B. Hylemon, William M. Pandak Jr., Guangji Wang, Xiaokun Li, Huiping Zhou

Microbiology and Immunology Publications

Background

HIV protease inhibitor (PI)-induced inflammatory response plays an important role in HIV PI-associated dyslipidemia and cardiovascular complications. This study examined the effect of berberine, a traditional herb medicine, on HIV PI-induced inflammatory response and further investigated the underlying cellular/molecular mechanisms in macrophages.

Methodology and Principal Findings

Cultured mouse J774A.1 macrophages and primary mouse macrophages were used in this study. The expression of TNF-α and IL-6 were detected by real-time RT-PCR and ELISA. Activations of ER stress and ERK signaling pathways were determined by Western blot analysis. Immunofluorescent staining was used to determine the intracellular localization of RNA binding protein …

Improving The Web Mastering Curriculum For The Included Classroom, Charles Zascavage, Victoria Zascavage Ph.D.

Electronic Journal for Inclusive Education

Following the mandates of the 2004 Individuals with Disabilities Deduction Improvement Act (IDIEA) and No Child Left Behind (2001) high schools have included students with cognitive disabilities into business classes. Although some teachers believe that the inclusion of mild to moderate intellectually disabled students into the general business education classroom may increases academic achievement for the special needs student; it continues to be widely debated as to whether it benefits the typical student or not. This study examined the issues of inclusion from the perception of a business faculty member, a special education district supervisor, a high school special education …

Neuropeptide Y Rs16147 Single Nucleotide Polymorphism Is Associated With Heavy Drinking And Severity Of Alcohol Dependence, Derick Vergne, Raymond Anton, Konstantin Voronin, Abraham Tiffany, Hugh Myrick, Caleb Canders, Garrick Klaybor, Patrick Randall, Joe Schacht

Posters

No abstract provided.

Eliminating The Underlying Cause Of Poverty As A Means To Global Economic Recovery, Robert Ashford

College of Law - Faculty Scholarship

The public analysis of the causes of the current recession and the ways to achieve economic recovery generally proceed on the widely-shared, tacit assumption that there is that there is no substantial, first-order connection between the recession and the failure to address the problem of systemic poverty. Otherwise, the need to alleviate systemic poverty and needed solutions to promote economic recovery would be commonly addressed in the same discussions; and they are not. This widely-shared, tacit assumption is false. The failure to reverse systemic poverty is the fundamental cause of current economic crisis. Recessions (and sub-optimal growth) occur when a …

Two Cheers For Feasible Regulation: A Modest Response To Masur And Posnera, David M. Driesen

College of Law - Faculty Scholarship

This article compares the relative merits of feasibility and cost-benefit based regulation, responding to a recent article by Jonathan Masur and Eric Posner on this topic. Normatively, it shows that the lack of correlation between non-subsistence consumption and welfare supports the argument that regulation should be strict, unless widespread plant shutdowns, which would seriously impact well-being, are involved. It shows that a host of practical defects Masur and Posner find in feasibility analysis would infect cost-benefit analysis as well. In light of the importance of cost's distribution, serious regard for individual well-being supports the feasibility principle better than a cost-benefit …

With Bases Loaded, Alito Hits A Home Run, Kristin A. Collins

Vanderbilt Law Review

No abstract provided.

Conservation-Reliant Species And The Future Of Conservation, Dale Goble

Articles

Species threatened with extinction are the focus of mounting conservation concerns throughout the world. Thirty-seven years after passage of the U.S. Endangered Species Act in 1973, we conclude that the Act’s underlying assumption—that once the recovery goals for a species are met it will no longer require continuing management—is false. Even when management actions succeed in achieving biological recovery goals, maintenance of viable populations of many species will require continuing, species-specific intervention. Such species are “conservation reliant.” To assess the scope of this problem, we reviewed all recovery plans for species listed as endangered or threatened under the Act. Our …

Pearson, Iqbal, And Procedural Judicial Activism, Goutam U. Jois

Florida State University Law Review

No abstract provided.

Divergent Worldviews In Ron Rash's "Serena", Brenda Dye Stephens

MA in English Theses

Ron Rash, through Serena, captures the often misunderstood complex nature of the Appalachian people in the early twentieth century and the effects of human centered environmental changes on this culture and natural landscape. The focus of this analysis involves viewing Serena through the lens of ecofeminism and introducing Rash's vision of the important interrelationship between landscape and culture, particularly in light of the historical outsider vision and its impact upon the people of Appalachia.

The culture and natural environment of the Appalachian people are revealed through the gazes of the characters. Through the fictional viewpoints in Serena,Rash creates a …

Between The Way To The Cross And Emmaus: Deconstructing Identity In The 325 Ce Council Of Nicaea And "The Shack", Trevar Simmons

MA in English Theses

This paper argues that when Christians acknowledge the deconstruction of their identity surrounding orthodoxy/heresy, Christians can embody the imitatio Christi and imago Dei. The argument begins by analyzing how Christians construct their identity along the orthodoxy/heresy lines by investigating a 2009 Bible burning by Amazing Grace Baptist Church in Canton, NC. Reaching into the past and present, deconstruction is found in a prototypical orthodoxy/heresy debate at the 325 CE Council of Nicaea and the modern hubbub in and surrounding William Paul Young's novel The Shack.

The Southeastern Librarian V. 57, No. 4 (Winter 2010) Complete Issue

The Southeastern Librarian

Complete issue of The Southeastern Librarian, volume 57, No. 4 (Winter 2010).

State News

The Southeastern Librarian

Recent developments from SELA member institutions.

2009 Annual Report Town Of Bethlehem, New Hampshire., Bethlehem Town Representatives

Bethlehem, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report For The Town Of Benton, New Hampshire Year Ending December 31, 2009., Benton Town Representatives

Benton, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Relationship Of Circulating Ghrelin And Leptin Concentrations In Beef Cattle Exhibitingdifferences In Composition Of Gain, J.S. Jennings, R.H. Pritchard, K.W. Bruns, D.H. Keisler, A.E. Wertz-Lutz

South Dakota Beef Report, 2010

Beef steers (n = 72) of similar age, weight (651 ± 3.1 lb), and genetic background (Angus crossbred) were used to determine the effects of growing period diet on the relationship of plasma ghrelin and leptin concentrations with growth performance and carcass composition. At trial initiation (d 0), 8 steers were harvested for initial carcass composition. The remaining 64 steers were allotted, by weight, to pen and treatment was assigned randomly. Treatments were 1) a high‐forage diet fed during the growing period (0‐116 d) followed by a high‐concentrate diet during the finishing period (117‐209 d; GRW‐FNSH) or 2) a high‐concentrate …

Social Management Networks: Analysis Of Postings In Facebook Groups Related To Wildlife Management And Prospects For Data Collection Issues In Information Systems, G. Kent Webb

Faculty Publications, Information Systems & Technology

Rapid acceptance and development of social network applications provide opportunities to gather data at low costs and to allow for coordinated use of this information for management. The phrase “social management networks” is proposed to focus study on social networks used for management objectives. This paper examines frequency of postings on Facebook groups related to wildlife management in order to see how this application is being developed to support these social management networks. Also, a survey of college business students is analyzed to see how social networking applications might be used to support environmental scanning using surveys. The results suggest …

KV4.2 Channels Tagged In The S1-S2 Loop For Alpha-Bungarotoxin Binding Provide A New Tool For Studies Of Channel Expression And Localization, Leonard Moise, Jing Liu, Evgeny Pryazhnikov, Leonard Khiroug, Andreas Jeromin, Edward Hawrot

Cell and Molecular Biology Faculty Publications

We report the first successful insertion of an engineered, high-affinity alpha-bungarotoxin (Bgtx) binding site into a voltage-gated ion channel, K_V4.2, using a short, intra-protein embedded sequence (GGWRYYESSLEPYPDGG), derived from a previously described mimotope peptide, HAP. A major benefit to this approach is the ability to live-image the distribution and fate of functional channels on the plasma membrane surface. The Bgtx binding sequence was introduced into the putative extracellular loop between the S1 and S2 transmembrane domains of K_V4.2. Following co-expression with KChIP3 in tsA201 cells, S1-S2 HAP-tagged channels express at levels comparable to wild-type K_{V …}

Emerging Importance Of Neuron-Satellite Glia Interactions Within Trigeminal Ganglia In Craniofacial Pain, Paul L. Durham, F. G. Garrett

College of Natural and Applied Sciences

Pain in the head and face, which can be very severe and debilitating, often involves activation of trigeminal ganglion nerves. The craniofacial symptoms can manifest as acute or transient conditions such as toothaches and headaches, or can transform into more chronic conditions such as migraine, rhinosinusitis, temporomandibular joint (TMJ) disorder, or trigeminal neuralgia. Traditionally, it is known that peripheral tissue injury or inflammation leads to excitation of trigeminal nerves that release inflammatory molecules in the periphery as well as facilitate transmission of nociceptive signals to the central nervous system. However, findings from recent studies have demonstrated that peripheral tissue injury …

How Shall I Praise Thee? Brian Leiter On Respect For Religion, Andrew Koppelman

Faculty Working Papers

In two recent papers, Brian Leiter argues that there is no good reason for law to single out religion for special treatment, and that religion is not an apt candidate for respect in the "thick" sense of being an object of favorable appraisal. Both arguments depend on a radically impoverished conception of what religion is and what it does. In this paper, I explain what Leiter leaves out, and offer an hypothesis about why. I also engage with some related reflections by Simon Blackburn and Timothy Macklem, both of whom influence, in different ways, Leiter's analysis.

Careful With That Gun: Lee, George, Wax, And Geach On Gay Rights And Same-Sex Marriage, Andrew Koppelman

Faculty Working Papers

Many Americans think that homosexual sex is morally wrong and oppose same-sex marriage. Philosophers trying to defend these views have relied on two strategies. One is to claim that such sex is wrong irrespective of consequences: there is something intrinsic to sex that makes it only licit when it takes place within a heterosexual marriage (in which there is no contraception or possibility of divorce). Patrick Lee and Robert P. George have developed and clarified this claim. The second strategy focuses on consequences: the baleful effects on heterosexual families of societal tolerance for homosexuality. Amy Wax (who is not a …

No Respect: Brian Leiter On Religion, Andrew Koppelman

Faculty Working Papers

In two recent papers, Brian Leiter argues that there is no good reason for law to single out religion for special treatment, and that religion is not an apt candidate for respect in the "thick" sense of being an object of favorable appraisal. Both arguments depend on a radically impoverished conception of what religion is and what it does. In this paper, I explain what Leiter leaves out, and offer an hypothesis about why. I also engage with some related reflections by Simon Blackburn and Timothy Macklem, both of whom influence, in different ways, Leiter's analysis.

Public And Private As Viewed Through The Work Of The Muhtasib, Kristen Stilt, Roy Mottahedeh

Faculty Working Papers

This article examines the distinctions between public and private space in classical Islamic law through the work of the muhtasib, a legal official charged with the inspection of public places and behavior in towns of the premodern Middle East and North Africa (and in some Muslim communities outside of these areas).

Can Any Legal Theory Constrain Any Judicial Decision?, Anthony D'Amato

Faculty Working Papers

A growing number of legal scholars have recently revived the American legal realist thesis that legal theory does not dictate the result in any particular case because legal theory itself is indeterminate. A more radical group has added that theory can never constrain judicial practice. I will present a spectrum of types of legal theories to demonstrate that the position of the more radical group of writers is correct—that legal theory is inherently incapable of identifying which party should win any given case.

State Responsibility For The Exportation Of Nuclear Power Technology, Anthony D'Amato, Kirsten H. Engel

Faculty Working Papers

Should nations that export nuclear power plants to developing countries be potentially liable to the people of those countries for catastrophic accidents? Risk of accident can be reduced if international law compels upgrading of safety design and construction of nuclear plants. Both the international law of state responsibility and an international regulatory agency have roles to play.

Cross-Country Adoption: A Call To Action, Anthony D'Amato

Faculty Working Papers

Although a free press is an integral part of democratic governance, intercountry adoption is one case in which the media makes it virtually impossible for governments to send children abroad for adoption. A country (State A) which gives up a child for intercountry adoption should receive a "credit" for that child which will entitle any other family within State A that may want to adopt a child to priority on the list at the Vatican. The second major function for the Intercountry Adoption Agency might be called the "annual report" function. All adoptive parents who take a child from the …

The Coerciveness Of International Law, Anthony D'Amato

Faculty Working Papers

This article shows that an important part of the deep structure of international law is its self-referential strategy of employing its own rules to protect its rules. International law tolerates a principled violation of its own rules when necessary to keep other rules from being broken. It extends a legal privilege to states to use coercion against any state that has selfishly attempted to transgress its international obligations. International law thus protects itself through the opportunistic deployment of its own rules.

World Conferences And The Cheapening Of International Norms, Anthony D'Amato

Faculty Working Papers

As long as we understand that world conferences only address problems, we will not be disappointed in them. We will only be disappointed if we think that a world conference is supposed to solve problems. Is there any point in getting a lot of people together, at great expense, just to address a problem without any prospect of solving it? My answer is a qualified yes. A world conference is a cultural artifact. It has an impact upon our collective sense of civilization.