Digital Commons Network^™

Bioluminescence To Reveal Structure And Interaction Of Coastal Planktonic Communities, Mark A. Moline, Shelley M. Blackwell, James F. Case, Steven H.D. Haddock, Christen M. Herren, Cristina M. Orrico, Eric Terrill

Biological Sciences

Ecosystem function will in large part be determined by functional groups present in biological communities. The simplest distinction with respect to functional groups of an ecosystem is the differentiation between primary and secondary producers. A challenge thus far has been to examine these groups simultaneously with sufficient temporal and spatial resolution for observations to be relevant to the scales of change in coastal oceans. This study takes advantage of general differences in the bioluminescence flash kinetics between planktonic dinoflagellates and zooplankton to measure relative abundances of the two groups within the same-time space volume. This novel approach for distinguishing these …

Accumulation Of Artemisinin Trioxane Derivatives Within Neutral Lipids Of Plasmodium Falciparum Malaria Parasites Is Endoperoxide-Dependent, Carmony L. Hartwig, Andrew S. Rosenthal, John D'Angelo, Carol E. Griffin, Gary H. Posner, Roland A. Cooper

Collected Faculty Scholarship

The antimalarial trioxanes, exemplified by the naturally occurring sesquiterpene lactone artemisinin and its semi-synthetic derivatives, contain an endoperoxide pharmacophore that lends tremendous potency against Plasmodium parasites. Despite decades of research, their mechanism of action remains unresolved. A leading model of anti-plasmodial activity hypothesizes that iron-mediated cleavage of the endoperoxide bridge generates cytotoxic drug metabolites capable of damaging cellular macromolecules. To probe the malarial targets of the endoperoxide drugs, we studied the distribution of fluorescent dansyl trioxane derivatives in living, intraerythrocytic-stage Plasmodium falciparum parasites using microscopic imaging. The fluorescent trioxanes rapidly accumulated in parasitized erythrocytes, localizing within digestive vacuole-associated neutral lipid …

Prism #36, February 2009, Office Of The Provost

Prism: Western Michigan University's Newsletter for Academic Affairs

No abstract provided.

The Faculty Notebook, February 2009, Provost's Office

Faculty Notebook

The Faculty Notebook is published periodically by the Office of the Provost at Gettysburg College to bring to the attention of the campus community accomplishments and activities of academic interest. Faculty are encouraged to submit materials for consideration for publication to the Associate Provost for Faculty Development. Copies of this publication are available at the Office of the Provost.

Olanzapine And Risperidone Disrupt Conditioned Avoidance Responding In Phencyclidine-Pretreated Or Amphetamine-Pretreated Rats By Selectively Weakening Motivational Salience Of Conditioned Stimulus, Ming Li, Wei He, Alexa Mead

Department of Psychology: Faculty Publications

The rat conditioned avoidance response model is a well-established preclinical behavioral model predictive of antipsychotic efficacy. All clinically approved antipsychotic drugs disrupt conditioned avoidance responding – a feature that distinguishes them from other psychotherapeutics. We previously showed that the typical antipsychotic drug haloperidol disrupts avoidance responding by progressively attenuating the motivational salience of the conditioned stimulus (CS) in normal rats. In this study, using two pharmacological rat models of schizophrenia [e.g. phencyclidine (PCP) or amphetamine sensitization], we examined whether atypicals such as olanzapine or risperidone disrupt avoidance responding through the same behavioral mechanism. Rats were first pretreated with PCP, amphetamine, …

Regarding Women: Philo And Paul As Two Women In A Stoic World, Karissa Worst

Doctor of Ministry

This thesis investigates the views and lives of Philo of Alexandria and the Apostle Paul in regard to women in creation, the fall of humanity, and life. Particularly, it looks at the influence of Stoic thought upon Philo' s and Paul's view of women. We recognize that the common culture and thought of the time greatly shapes human beings and so we acknowledge the influence that Hellenization had upon these men. They utilized the accepted philosophies of their time to develop their theologies and teach their audiences. We address the low philosophical view of women held in Greek philosophy. However, …

Methods To Quantify Variable Importance: Implications For Theanalysis Of Noisy Ecological Data, Kim Murray, Mary M. Conner

Wildland Resources Faculty Publications

Determining the importance of independent variables is of practical relevance to ecologists and managers concerned with allocating limited resources to the management of natural systems. Although techniques that identify explanatory variables having the largest influence on the response variable are needed to design management actions effectively, the use of various indices to evaluate variable importance is poorly understood. Using Monte Carlo simulations, we compared six different indices commonly used to evaluate variable importance; zero-order correlations, partial correlations, semipartial correlations, standardized regression coefficients, Akaike weights, and independent effects. We simulated four scenarios to evaluate the indices under progressively more complex circumstances …

“We Are God’S Children, Y’All:” Race, Gender, And Sexuality In Lesbian- And Gay-Affirming Congregations, Krista Mcqueeney

Criminology Faculty Publications

This article examines how lesbian, gay, and straight-but-affirming members of lesbian- and gay-affirming churches in the South challenged a deep-rooted Christian belief in homosexual sin. Data are taken from 200 hours of participant observation and 25 in-depth interviews in two Protestant churches: one predominantly black, working class, lesbian, and evangelical, and the other mostly white, middle class, heterosexual, and liberal. I identify three strategies lesbian, gay, and straight-but-affirming church members used to accommodate—but not assimilate—to heteronormative conceptions of the “good Christian.” First, some black lesbians minimized their sexuality as secondary to the Christian identity. Second, most lesbian and gay members—both …

Health Professionals’ Roles In Animal Agriculture, Climate Change, And Human Health, Aysha Z. Akhtar, Michael Greger, Hope Ferdowsian, Erica Frank

Human Health Collection

What we eat is rapidly becoming an issue of global concern. With food shortages, the rise in chronic disease, and global warming, the impact of our dietary choices seems more relevant today than ever. Globally, a transition is taking place toward greater consumption of foods of animal origin, in lieu of plantbased diets. With this transition comes intensification of animal agriculture that in turn is associated with the emergence of zoonotic infectious diseases, environmental degradation, and the epidemics of chronic disease and obesity. Health professionals should be aware of these trends and consider them as they promote healthier and more …

Effect Of Noxious Stimulation Upon Antipredator Responses And Dominance Status In Rainbow Trout, Paul J. Ashley, Sian Ringrose, Katie L. Edwards, Emma Wallington, Catherine R. Mccrohan, Lynne U. Sneddon

Aquaculture Collection

A potentially painful experience may modify normal behavioural responses. To gauge the importance of pain relative to predation or social status, we presented competing stimuli, a predator cue or an unfamiliar social group, to two groups of noxiously treated rainbow trout, Oncorhynchus mykiss. In the predator cue experiment, fish were classified as bold or shy. Noxiously stimulated fish did not show antipredator responses, suggesting that pain is the imperative. In the social status experiment, noxiously stimulated fish held individually and undisturbed showed an increase in respiration rate and plasma cortisol. As a comparison, we used the dominant or subordinate fish …

The Most Widely Publicized Gender Problem In Human Genetics, William D. Stansfield, Matthew A. Carlton

Biological Sciences

In two-child families containing at least one boy, the expected probability that such a family has two boys is 1/3, provided that the boy/girl (B/G) ratio is 1.0 and the population to which they belong has a binomial distribution of BB, (BG + GB), and GG families. It is commonly known that in most human populations the sex ratio at birth (i.e., the ratio of the number of boys to the number of girls) is greater than 1.0. Teachers and textbook writers seldom discuss the more realistic expected distributions in populations where the sex ratio is greater than 1.0. We …

Synthesis: Evolutionary Ecology Of Microbial Wars: Within-Host Competition And (Incidental) Virulence, Sam Brown, Fredrik Inglis, François Taddei

Biology Department Faculty Works

Invading an occupied niche is a formidable ecological challenge, and one of particular human importance in the context of food-borne microbial pathogens. We discuss distinct categories of invader-triggered environmental change that facilitate invasion by emptying their niche of competitors. Evidence is reviewed that gut bacteria use such strategies to manipulate their environment (via bacteriocins, temperate phage viruses or immuno-manipulation) at the expense of their competitors are reviewed. The possible virulence implications of microbial warfare among multiple co-infecting strains are diverse. Killing competitors can reduce virulence by reducing overall microbial densities, or increase virulence if for example the allelopathic mechanism involves …

Evolutionary Ecology Of Microbial Wars: Within-Host Competition And (Incidental) Virulence, Sam Brown, R Inglis, François Taddei

Biology Department Faculty Works

Invading an occupied niche is a formidable ecological challenge, and one of particular human importance in the context of food-borne microbial pathogens. We discuss distinct categories of invader-triggered environmental change that facilitate invasion by emptying their niche of competitors. Evidence is reviewed that gut bacteria use such strategies to manipulate their environment (via bacteriocins, temperate phage viruses or immuno-manipulation) at the expense of their competitors are reviewed. The possible virulence implications of microbial warfare among multiple co-infecting strains are diverse. Killing competitors can reduce virulence by reducing overall microbial densities, or increase virulence if for example the allelopathic mechanism involves …

Development And Validation Of An Empirical Free Energy Function For Calculating Protein–Protein Binding Free Energy Surfaces, Joseph Audie

Chemistry & Physics Faculty Publications

In a previous paper, we described a novel empirical free energy function that was used to accurately predict experimental binding free energies for a diverse test set of 31 protein–protein complexes to within ≈1.0 kcal. Here, we extend that work and show that an updated version of the function can be used to (1) accurately predict native binding free energies and (2) rank crystallographic, native-like and non-native binding modes in a physically realistic manner. The modified function includes terms designed to capture some of the unfavorable interactions that characterize non-native interfaces. The function was used to calculate one-dimensional binding free …

Fisheries Research Report No. 188 - Results Of The 2007 Survey Of The Albany Marine Area For Introduced Marine Species, Justin I. Mcdonald, Fred E. Wells, Michael J. Travers

Fisheries Research Reports

A survey of the Albany marine area (King George Sound, Princess Royal Harbour and Oyster Harbour) for introduced marine pest species was conducted in 2007. This survey was trialling the new system of monitoring for introduced marine pests developed by the National Introduced Marine Pests Coordination Group (NIMPCG). This study represents one of the first trials of this system (the first trial commenced in South Australia is still ongoing). In this survey fifty-two of the fifty-five potential pest species were targeted. Three species were excluded on the basis of salinity and/or temperature tolerances being exceeded. A wide variety of sampling …

Fisheries Research Report No. 183 - Development Of A Long-Term Program To Monitor Coastal Communities Within The Swan Region, Lynda M. Bellchambers

Fisheries Research Reports

Marine benthic communities along the metropolitan coast of Western Australia are varied and unique. The southward flowing Leeuwin Current brings warm water and tropical recruits whilst the cooler counter current, the Capes Current, brings the temperate recruits. The result is a mosaic of tropical species intermingled with the dominant temperate species. These areas sustain varied fish and invertebrate communities making this coast a highly desirable location for recreational and commercial use. Management strategies are in place that attempt to maintain the sustainability of this area including various fishery restrictions and the implementation of areas zoned as sanctuary zones (no-take). However, …

Fisheries Research Report No. 185 - Performance Indicators, Biological Reference Points And Decision Rules For Western Australian Abalone Fisheries (Haliotis Sp.): (1) Standardised Catch Per Unit Effort, Anthony M. Hart, Frank Fabris, Nick Caputi

Fisheries Research Reports

This report summarises the performance indicators (PIs) and biological reference points (BRPs) developed from standardised catch per unit effort (SCPUE) models of the Western Australian abalone fisheries. It also outlines analysis and consultation processes used to construct these indicators. Other PIs, such as those relating to harvest rate and recruitment, will be developed when more fishery independent data becomes available.

A comprehensive 7-step process was utilised to develop PIs.

1) The Abalone Management and Advisory Committee (AbMac) considered options and advised that in the short-term, catch and effort trends be reviewed with other potential indicators to be considered at a …

Benchmarks 2009, February 20, The Rockefeller University

BenchMarks 2009

BenchMarks. Friday, February 20, 2009

The community newsletter of The Rockefeller University

BenchMarks is published monthly and is distributed on the campus of The Rockefeller University. It produced by the Office of Communications and Public Affairs

Ecological Specialization In A Spatially Structured Population Of The Thermophilic Cyanobacterium Mastigocladus Laminosus, Scott R. Miller, Carin Williams, Aaron L. Strong, Darla Carvey

Biological Sciences Faculty Publications

Laboratory evolution experiments suggest the potential for microbial populations to contribute significant ecological variation to ecosystems, yet the functional importance of genetic diversity within natural populations of microorganisms is largely unknown. Here, we investigated the distribution of genetic and phenotypic variation for a population of the cyanobacterium Mastigocladus laminosus distributed along the temperature gradient of White Creek, Yellowstone NP. A total of 153 laboratory strains were directly isolated from five sites with mean annual temperatures ranging between 39 and 54 C. Genetic characterization at four nitrogen metabolism genes identified 15 closely related lineages in the population sample. These lineages were …

Extensive Phylogenetic Analysis Of A Soil Bacterial Community Illustrates Extreme Taxon Evenness And The Effects Of Amplicon Length, Degree Of Coverage, And Dna Fractionation On Classification And Ecological Parameters, Sergio E. Morales, Theodore F. Cosart, Jesse Johnson, William Holben

Computer Science Faculty Publications

To thoroughly investigate the bacterial community diversity present in a single composite sample from an agricultural soil and to examine potential biases resulting from data acquisition and analytical approaches, we examined the effects of percent G+C DNA fractionation, sequence length, and degree of coverage of bacterial diversity on several commonly used ecological parameters (species estimation, diversity indices, and evenness). We also examined variation in phylogenetic placement based on multiple commonly used approaches (ARB alignments and multiple RDP tools). The results demonstrate that this soil bacterial community is highly diverse, with 1,714 operational taxonomic units demonstrated and 3,555 estimated (based on …

Ratiometric Single-Nanoparticle Oxygen Sensors For Biological Imaging, Changfeng Wu, Barbara Bull, Kenneth Christensen, Jason Mcneill

Publications

It makes sense: Conjugated polymer nanoparticles doped with a platinum porphyrin dye exhibit bright phosphorescence that is highly sensitive to the concentration of molecular oxygen. The small size, extraordinary brightness, excellent sensitivity, and ratiometric emission, together with the demonstration of single-particle sensing and cellular uptake, indicate the potential of the nanoparticle sensors for quantitative mapping of local molecular oxygen concentration.

Status, Trends, And Conservation Of Eelgrass In Atlantic Canada And The Northeastern United States: Workshop Report, Hilary A. Neckles, Al R. Hanson, Phil Colarusso, Robert N. Buchsbaum, Fred T. Short

Publications

Eelgrass (Zostera marina L) is the dominant seagrass occurring in eastern Canada and the northeastern United States, where it often forms extensive meadows in coastal and estuarine areas. Eelgrass beds are extremely productive and provide many valuable ecological functions and ecosystem services. They serve as critical feeding and nursery habitat for a wide variety of commercially and recreationally important fish and shellfish and as feeding areas for waterfowl and other waterbirds. Eelgrass detritus is also transported considerable distances to fuel offshore food webs. In addition, eelgrass beds stabilize bottom sediments, dampen wave energy, absorb nutrients from surrounding waters, and retain …

Ua35/1 Doers & Deeds Vol. 7, No. 9, Wku Provost

WKU Administration Documents

Newsletter created by the WKU Provost & Vice President of Academic Affairs to highlight the activities of faculty, staff and alumni.

Traveling-Wave Electrophoresis For Microfluidic Separations, Boyd F. Edwards, A. T. Timperman, R. Lloyd Carroll, K. Jo, J. M. Mease, J. E. Schiffbauer

All Physics Faculty Publications

Models and microfluidic experiments are presented of an electrophoretic separation technique in which charged particles whose mobilities exceed a tunable threshold are trapped between the crests of a longitudinal electric wave traveling through a stationary viscous fluid. The wave is created by applying periodic potentials to electrode arrays above and below a microchannel. Predicted average velocities agree with experiments and feature chaotic attractors for intermediate mobilities.

Northern Fur Seal Rookery Photo Archive: Aerial And Ground-Level Photos, Pribilof Islands, Alaska, 1895 - 2006, Kymberly M. Yano, Jessica Y. Tingg, Charles W. Fowler

United States Department of Commerce: Staff Publications

The northern fur seal (Callorhinus ursinus) has been the subject of recorded history for more than two centuries (Scheffer et al. 1984, Scott et al. 2006). It has a long history of being commercially harvested for its valuable pelts (Roppel 1984). Recently, however, fur seals are being seen as one of many species reflecting the conditions of their environment, especially an environment increasingly altered by human influence. The Pribilof Islands fur seal population is currently listed as depleted under terms of the U.S. Marine Mammal Protection Act owing to numbers greatly reduced from those observed historically (National Marine …

For 462.01a: Rangeland Ecology, Donald J. Bedunah

University of Montana Course Syllabi, 1990-2010

No abstract provided.

Pubh 595.52: The Practice Of International Health, Lisa Pascopella, Craig A. Molgaard

University of Montana Course Syllabi, 1990-2010

No abstract provided.

Sw 423.01: Addiction Studies, Cynthia L. Garthwait

University of Montana Course Syllabi, 1990-2010

No abstract provided.

Sw 511.01: Hbse Ii - Difference, Diversity, And Oppression, Danielle F. Wozniak

University of Montana Course Syllabi, 1990-2010

No abstract provided.

Sw 300.01: Human Behavior And The Social Environment, Cynthia L. Garthwait

University of Montana Course Syllabi, 1990-2010

No abstract provided.