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Articles 11251 - 11280 of 16981
Full-Text Articles in Entire DC Network
Electrical Activity And Exocytotic Correlates Of Biphasic Insulin Secretion From Β-Cells Of Canine Islets Of Langerhans, Stanley Misler, Zhuan Zhou, Adam S. Dickey, Amelia M. Silva, David M. Pressel, David W. Barnett
Electrical Activity And Exocytotic Correlates Of Biphasic Insulin Secretion From Β-Cells Of Canine Islets Of Langerhans, Stanley Misler, Zhuan Zhou, Adam S. Dickey, Amelia M. Silva, David M. Pressel, David W. Barnett
Open Access Publications
No abstract provided.
Synchronous Gene Expression Of The Yersinia Enterocolitica Ysa Type Iii Secretion System And Its Effectors, Kimberly A. Walker, Virginia L. Miller
Synchronous Gene Expression Of The Yersinia Enterocolitica Ysa Type Iii Secretion System And Its Effectors, Kimberly A. Walker, Virginia L. Miller
Open Access Publications
No abstract provided.
Ompa Of Uropathogenic Escherichia Coli Promotes Postinvasion Pathogenesis Of Cystitis, Tracy F. Nicholson, Kristin M. Watts, David A. Hunstad
Ompa Of Uropathogenic Escherichia Coli Promotes Postinvasion Pathogenesis Of Cystitis, Tracy F. Nicholson, Kristin M. Watts, David A. Hunstad
Open Access Publications
No abstract provided.
Recombinant Listeria Monocytogenes Expressing A Cell Wall-Associated Listeriolysin O Is Weakly Virulent But Immunogenic, Javier A. Carrero, Boris Calderon, Hector Vivanco-Cid, Emil R. Unanue
Recombinant Listeria Monocytogenes Expressing A Cell Wall-Associated Listeriolysin O Is Weakly Virulent But Immunogenic, Javier A. Carrero, Boris Calderon, Hector Vivanco-Cid, Emil R. Unanue
Open Access Publications
No abstract provided.
A Role For Dynein In The Inhibition Of Germ Cell Proliferative Fate, Maia Dorsett, Tim Schedl
A Role For Dynein In The Inhibition Of Germ Cell Proliferative Fate, Maia Dorsett, Tim Schedl
Open Access Publications
No abstract provided.
A Genomic Score Prognostic Of Outcome In Trauma Patients, J. P. Cobb, Et Al.
A Genomic Score Prognostic Of Outcome In Trauma Patients, J. P. Cobb, Et Al.
Open Access Publications
No abstract provided.
Ua19 Championship Effort, Wku Athletics
Ua19 Championship Effort, Wku Athletics
WKU Administration Documents
WKU Athletics annual report for 2008-2009 includes data regarding student athletes and achievements in team and individual sports.
Explore, Spring 2009, Vol. 12, No. 2: Sustainability At Santa Clara University, Ignatian Center For Jesuit Education
Explore, Spring 2009, Vol. 12, No. 2: Sustainability At Santa Clara University, Ignatian Center For Jesuit Education
explore
Contents: Sustainability in Catholic Higher Education; The Theology of Sustainability; Empowering Teachers as Environmentally Literate: Ethical Considerations; Where is Sustainability Happening at SCU?; Toward a Culture of Sustainability on Campus; Water for Life: A Journey to Nicaragua Exploring Sustainable Development; Upcoming Events; Next Issue
Evaluation Of Pilo Substrate Specificity Using Normally Non-Glycosylated Proteins In Pseudomonas Aeruginosa, Matthew A. Henkel
Evaluation Of Pilo Substrate Specificity Using Normally Non-Glycosylated Proteins In Pseudomonas Aeruginosa, Matthew A. Henkel
Electronic Theses and Dissertations
P. aeruginosa 1244 (PA1244) possesses an O-linked glycosylation system by which the glycosyltransferase, PilO, transfers a single preassembled O-antigen repeating unit to the C-terminal serine residue of pilin as a posttranslational modification. Previous work has shown that the group II pilin of PA103 can be engineered for glycosylation by extending a C-terminal serine away from the surface with a short stretch of alanine residues (Horzempa et al., 2006a). As an extension of that study, several normally non-glycosylated proteins [PA683 pilin, PA1244 PilA-E. coli (EC) alkaline phosphatase (PhoA) fusion, and EC PhoA] were engineered with C-terminal amino acid extensions and assessed …
Demographics, Activity, And Habitat Selection Of The Eastern Box Turtle (Terrapene C. Carolina) In West Virginia, Justin Adam Weiss
Demographics, Activity, And Habitat Selection Of The Eastern Box Turtle (Terrapene C. Carolina) In West Virginia, Justin Adam Weiss
Theses, Dissertations and Capstones
Little is known about the eastern box turtle, Terrapene c. carolina, in West Virginia. The purpose of this study was to compare demographic data between two populations of box turtles, to determine which environmental parameter(s) influence activity patterns, and to describe the optimal habitat of the box turtles at two study sites (Lake and State Park) at Beech Fork Wildlife Management Area. I observed male-skewed sex ratios and low numbers of juveniles in both populations. Male turtles were larger than females in carapace length, but females were larger in carapace height. Turtles at the Lake site exhibited greater body mass …
Analysis Of Factors Influencing West Virginia Secondary Biology And Science Teacher Attrition Rates, Seth Perry
Analysis Of Factors Influencing West Virginia Secondary Biology And Science Teacher Attrition Rates, Seth Perry
Theses, Dissertations and Capstones
The high rate of attrition for beginning teachers has been blamed on many factors. Nationally these include low pay, urban versus rural school settings, age, with younger teachers leaving sooner, and other variables making a complex problem with no clear component responsible for the loss of teachers. This study examined the self reported variables that contribute to high school teachers in West Virginia leaving their profession. An electronic survey instrument was distributed to current secondary teachers across the state. Teachers were asked to respond to questions related to professional satisfaction, perceived value from students and parents, administrative support, content versus …
Wild Horse Gathering For The Red Desert Complex Wild Horse Herd Management Areas (Lost Creek, Stewart Creek, Green Mountain, Crooks Mountain, Antelope Hills), United States Department Of The Interior, Bureau Of Land Management
Wild Horse Gathering For The Red Desert Complex Wild Horse Herd Management Areas (Lost Creek, Stewart Creek, Green Mountain, Crooks Mountain, Antelope Hills), United States Department Of The Interior, Bureau Of Land Management
Environmental Assessments (WY)
This Environmental Assessment (EA) has been prepared to disclose and analyze the environmental consequences of gathering excess wild horses in the Red Desert Wild Horse Herd Management Area (HMA) Complex. The HMAs included in this complex are Lost Creek, Stewart Creek, Green Mountain, Crooks Mountain and Antelope Hills. The EA is a site-specific analysis of potential impacts that could result with the implementation of a proposed action or alternatives to the proposed action. The EA assists the BLM in project planning and ensuring compliance with the National Environmental Policy Act (NEPA), and in making a determination as to whether any …
Synthesis Of 12-Hete Using Asymmetric Phase-Transfer Catalysis, Michael A. Christiansen, M. B. Andrus
Synthesis Of 12-Hete Using Asymmetric Phase-Transfer Catalysis, Michael A. Christiansen, M. B. Andrus
Chemistry and Biochemistry Faculty Presentations
A new method of asymmetric phase-transfer-catalyzed alkylation is described. The synthetic utility of this method is demonstrated with the total syntheses of kurasoin A, kurasoin B, and S-naproxenTM, with current work toward S-equol. This methodology is currently being applied to an improved asymmetric total synthesis of the natural compound 12-S-HETE.
Effects Of Professional Development On Infusing Engineering Design Into High School Science, Technology, Engineering And Math (Stem) Curricula, Zanj Kano Avery
Effects Of Professional Development On Infusing Engineering Design Into High School Science, Technology, Engineering And Math (Stem) Curricula, Zanj Kano Avery
Dissertations
The purpose of this study was to examine the effects of professional development (PD) on the infusion of engineering design into high school curricula. Four inservice teachers with backgrounds in physics, chemistry, industrial education, math, and electrical engineering participated in the 2006 National Center of Engineering and Technology Education (NCETE)-sponsored PD workshops at California State University, Los Angeles (CSULA) and provided three sources of data that were used to answer the research question, “What are the effects of PD on infusing engineering design into high school science, technology, engineering, and math (STEM) curricula”? Three major themes emerged from the data. …
Living Green Is A Lifestyle Choice, Mardi Mileham
Living Green Is A Lifestyle Choice, Mardi Mileham
Linfield Magazine
Duncan Reid '10 is dedicated to living a sustainable lifestyle. He's made his mark on campus and with students, professors, and administrators, for his dedication to the environment.
Henberg Takes Holistic Approach, Laura Davis
Henberg Takes Holistic Approach, Laura Davis
Linfield Magazine
Long before the whisper of terms like global warming and carbon footprints, before SIGG bottles and reusable shopping bags, Marvin Henberg was already a committed environmental advocate.
Q & A With Dean Victoria Mcgillin, Linfield Magazine Staff
Q & A With Dean Victoria Mcgillin, Linfield Magazine Staff
Linfield Magazine
After 11 months on the job, Victoria McGillin, dean of faculty, discusses how success of a Linfield education can be measured.
Searching For A Cure For Cancer, Mardi Mileham
Searching For A Cure For Cancer, Mardi Mileham
Linfield Magazine
For Professor Anne Kruchten, cancer is more than a disease as she and her students pursue a research agenda to help improve understanding about how the disease spreads.
Nos-Based Biopolymers: Towards Novel Thromboresistant No-Release Materials, Charbel Abou Diwan
Nos-Based Biopolymers: Towards Novel Thromboresistant No-Release Materials, Charbel Abou Diwan
ETD Archive
Nitric Oxide releasing biopolymers have the potential to prolong vascular graft and stent potency without adverse systemic vasodilation. It was reported in literature that eNOS-overexpressing endothelial cell seeding of synthetic small diameter vascular grafts decreased human platelet aggregation by 46 and bovine aortic smooth muscle cell proliferation by 67.2 in vitro. We hypothesized that incorporating the enzyme nitric oxide synthase (NOS) in biocompatible polymeric matrix will provide a source of NO that utilizes endogenous compounds to maintain an unlimited supply of NO. To test this hypothesis, we have incorporated the enzyme nitric oxide synthase into a polyethyleneimine film using a …
Structural Studies Of Talin-Mediated Integrin Activation, Esen Bakhautdin
Structural Studies Of Talin-Mediated Integrin Activation, Esen Bakhautdin
ETD Archive
Activation of heterodimeric (alpha/beta) integrin transmembrane receptors by the cytoskeletal protein talin is essential for many important cell adhesive responses including cell-extracellular matrix contact, cell motility and survival. A key step in this process involves interaction of phosphotyrosine-binding (PTB) domain in the N-terminal head of talin (talin-H) with integrin beta3membrane-proximal cytoplasmic tails (beta-MP-CTs). Compared to talin-H, intact talin exhibits low potency in inducing integrin activation. Using TROSY NMR spectroscopy, we found that the large C-terminal rod domain of talin (talin-R) interacts with talin-H and allosterically restrains talin in a closed conformation. Structural, mutational, and biochemical analyses demonstrate that talin-R specifically …
Homeostatic Regulation Of Interleukin-4-Mediated Cell Signaling, Rikhia Chakraborty
Homeostatic Regulation Of Interleukin-4-Mediated Cell Signaling, Rikhia Chakraborty
ETD Archive
Cytokines are intracellular messengers that activate multiple signaling pathways and regulate cell survival, differentiation, migration, apoptosis and immune responses. We are investigating the homeostatic control of cytokine-mediated cell signaling using interleukin-4 (IL-4) as a model cytokine. Protein tyrosine phosphorylation is essential for cytokine-dependent signal transduction through the Janus Kinase-Signal Transducer and Activator of Transcription (Jak-STAT) pathway. Therefore, protein tyrosine dephosphorylation is a key mechanism providing the homeostatic control of the pathway. Here, we have shown for the first time that immediately following ligand-dependent activation, IL-4 receptor induces an intracellular calcium flux via insulin receptor substrate (IRS)-phosphoinositide 3-kinase (PI3K)-phospholipase C (PLC)-gamma …
Development Of A Focused Broadband Ultrasonic Transducer For High Resolution Fundamental And Harmonic Intravascular Imaging, Chaitanya K. Chandrana
Development Of A Focused Broadband Ultrasonic Transducer For High Resolution Fundamental And Harmonic Intravascular Imaging, Chaitanya K. Chandrana
ETD Archive
Intravascular ultrasound (IVUS) is increasingly employed for detection and evaluation of coronary artery diseases. Tissue Harmonic Imaging provides different tissue information that could additionally be used to improve diagnostic accuracy. However, current IVUS systems, with their unfocussed transducers, may not be capable of operating in harmonic imaging mode. Thus, there is a need to develop suitable transducers and appropriate techniques to allow imaging in multi modes for complementary diagnostic information. Focused PVDF TrFE transducers were developed using MEMS (Micro-Electro-Mechanical-Systems) compatible protocols. The transducers were characterized using pulse-echo techniques and exhibited broad bandwidth (110 at -6dB) with axial resolutions of Such …
Role Of Kcnma1 In The Pathogenesis Of Gepd Syndrome, Wei Du
Role Of Kcnma1 In The Pathogenesis Of Gepd Syndrome, Wei Du
ETD Archive
No abstract provided.
Regulation Of Monocyte Nadph Oxidase;Role Of Pattern Recognition Receptors, Deena H. Elsori
Regulation Of Monocyte Nadph Oxidase;Role Of Pattern Recognition Receptors, Deena H. Elsori
ETD Archive
No abstract provided.
Regulation Of Apoptosis By The Muscle Regulatory Transcription Factor Myod, Terri J. Harford
Regulation Of Apoptosis By The Muscle Regulatory Transcription Factor Myod, Terri J. Harford
ETD Archive
We have previously reported that the level of MyoD expression correlates with the level of apoptosis that occurs in a subpopulation of skeletal myoblasts induced to differentiate by serum withdrawal. Herein we document that MyoD expression dictates the apoptotic threshold in myoblasts and fibroblasts in response to a variety of apoptotic stimuli. Specifically, re-expression of MyoD in skeletal myoblasts rendered defective for both differentiation and apoptosis by the expression of oncogenic Ras restores their ability to undergo both differentiation and apoptosis in response to serum withdrawal. Further, using a fibroblast cell line expressing an estrogen receptor:MyoD fusion protein, we have …
Cofactor Control Of A Vital Enzymatic Reaction;The Effect Of Factor Va On Thrombin Formation During Blood Coagulation, Jamila Hirbawi
Cofactor Control Of A Vital Enzymatic Reaction;The Effect Of Factor Va On Thrombin Formation During Blood Coagulation, Jamila Hirbawi
ETD Archive
The LONG-TERM goal of our research is to study and analyze the structure and function of the factor V molecule in order to understand its regulatory effects on the natural process of hemostasis and its role in the life-threatening development of deep venous thrombosis. The SHORT-TERM goal of our research is to identify the amino acid residue(s) of factor V that interact with prothrombin during the assembly and function of the prothrombinase complex in order to fully understand its particular role in maintaining the integrity of the blood coagulation cascade. The final goal of the coagulation cascade is the formation …
Explaining Math Achievement;Personality, Motivation, And Trust, Ebru Kilic-Bebek
Explaining Math Achievement;Personality, Motivation, And Trust, Ebru Kilic-Bebek
ETD Archive
This study investigated the statistical significance of student trust next to the well-tested constructs of personality and motivation to determine whether trust is a significant predictor of course achievement in college math courses. Participants were 175 students who were taking undergraduate math courses in an urban public university. The Mini-Markers (Saucier, 1994), an adapted Student Trust Survey (Barnes, Adams & Forsyth, 2004, April), and the Motivated Strategies for Learning Questionnaire (Pintrich, Smith, Garcia & McKeachie, 1991) were used to measure students' Big-Five personality factors, trust in their math instructor, and motivational beliefs and strategies for their learning and performance in …
Imaging Of Tyramine-Substituted Hydrogels For Tissue Replacement, Ediuska V. Laurens
Imaging Of Tyramine-Substituted Hydrogels For Tissue Replacement, Ediuska V. Laurens
ETD Archive
Novel tyramine-based hyaluronan (HA) and collagen hydrogels have been developed in which cross-linking is accomplished via peroxidase-mediated dityramine linkages allowing direct cross-linking in vivo. These TB hydrogels possess advantageous physical properties, which include excellent biocompatibility and the ability to mimic the biological, structural and mechanical properties of normal, healthy tissues, including cartilage, and thus provide for synthetic, implantable biomaterials suitable for a wide range of tissue types. The efficacy of these TB-hydrogels has been previously tested in a number of clinically relevant animal models, which have evaluated their applicability for the repair/replacement of various tissues, including cartilage. Nevertheless, there exists …
Hemoprotein-Mediated Activation Of Nitroalkanes, Ling Li
Hemoprotein-Mediated Activation Of Nitroalkanes, Ling Li
ETD Archive
Chemicals and drugs are known to be metabolized mostly by Cytochrome P450 xenobiotic metabolizing enzymes. However, the detailed mechanism of nitro-compounds metabolism is still unclear. The activation of nitro-xenobiotics by heme-P450 enzymes is a potential explanation for the origin of nitro-compound carcinogenesis. Investigating the interaction of simple nitro-compounds with redox activity of heme enzymes is therefore critical to explore the mechanism and products of activation. In this study, multiple analytical methods and instrumentations are employed and graphic and simulation software such as Origin┬« and Digisim┬« are utilized to quantitatively derive parameters from experimental raw data. This study shows that myoglobin, …
Overcoming Barriers To Natural Orifice Translumenal Endoscopic Surgery (Notes), Steve J. Schomisch
Overcoming Barriers To Natural Orifice Translumenal Endoscopic Surgery (Notes), Steve J. Schomisch
ETD Archive
Natural Orifice Translumenal Endoscopic Surgery (NOTES) avoids skin incisions by accessing the abdominal cavity through natural orifices. Benefits include less pain, fewer complications and no scars. The aims of this study were to evaluate safety and efficacy of access techniques for natural orifice surgery, to investigate safety and efficacy of closure methodologies and to compare the inflammatory response induced by NOTES with that following conventional surgery. Access techniques were evaluated for safety and efficacy by measuring resultant injury and time required to access the peritoneal cavity in an acute porcine model. Four different gastrotomy closure modalities were evaluated for safety …