Entire DC Network | Open Access Articles | Digital Commons Network™

Inclusion Biogenesis And Reactivation Of Persistent Chlamydia Trachomatis Requires Host Cell Sphingolipid Biosynthesis, D. Kesley Robertson, Ling Gu, Regina K. Rowe, Wandy L. Beatty

Open Access Publications

No abstract provided.

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A Genomic Score Prognostic Of Outcome In Trauma Patients, J. P. Cobb, Et Al.

Open Access Publications

No abstract provided.

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The Human Dimension Of Global Climate Change, Edward Cameron

UC Law Environmental Journal

No abstract provided.

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Tomato Bushy Stunt Virus (Tbsv), A Versatile Platform For Polyvalent Display Of Antigenic Epitopes And Vaccine Design, Shantanu Kumar, Wendy Ochoa, Pratik Singh, Catherine Hsu, Anette Schneemann, Marianne Manchester, Mark Olson, Vijay Reddy

United States Army: Publications

Viruses-like particles (VLPs) are frequently being used as platforms for polyvalent display of foreign epitopes of interest on their capsid surface to improve their presentation enhancing the antigenicity and host immune response. In the present study, we used the VLPs of Tomato bushy stunt virus (TBSV), an icosahedral plant virus, as a platform to display 180 copies of 16 amino acid epitopes of ricin toxin fused to the C-terminal end of a modified TBSV capsid protein (NΔ52). Expression of the chimeric recombinant protein in insect cells resulted in spontaneous assembly of VLPs displaying the ricin epitope. Cryo-electron microscopy and image …

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American Society Of Parasitologists Newsletter, V. 31, No. 3, Winter 2009, Scott Lyell Gardner

American Society of Parasitologists: Newsletter

An issue of the American Society of Parasitologists' quarterly newsletter, also called the Journal of Parasitology Newsletter.

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Biology (Bims), Montclair State University

Course Descriptions

No abstract provided.

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Mathematics (Math), Montclair State University

Course Descriptions

No abstract provided.

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The Convent As Cultural Conduit: Irish Matronage In Early Modern Spain, Andrea Knox

Quidditas

Irish catholic women religious who migrated to Spain in the sixteenth and seventeenth centuries established a strong tradition of schools, hospitals and charitable institutions. Education and learning were important to Irish communities, and were recognised within Spain. Irish nuns and their convents were not part of an enclosed tradition and outreach work was a central aim. Sponsorship links between women were part of a collective plan, and cultural matronage by and for women appears to have been very effective. Censorship by the Inquisition and tridentine orthodoxy was contested by women’s religious houses which resisted censorship of book collections and art …

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Evaluating Aztreonam And Ceftazidime Pharmacodynamics With Escherichia Coli In Combination With Daptomycin, Linezolid, Or Vancomycin In An In Vitro Pharmacodynamic Model, Kerry L. Laplante, Sakoulas

Pharmacy Practice and Clinical Research Faculty Publications

In an in vitro pharmacodynamic model, linezolid attenuated the activity of aztreonam and ceftazidime against Escherichia coli. Conversely, synergy was detected at 24 and 48 h when daptomycin or vancomycin was added to aztreonam and ceftazidime. We conclude that significant yet underappreciated interactions may occur between gram-positive-spectrum and gram-negative-spectrum antibacterials.

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Activities Of Daptomycin And Vancomycin Alone And In Combination With Rifampin And Gentamicin Against Biofilm-Forming Methicillin-Resistant Staphylococcus Aureus Isolates In An Experimental Model Of Endocarditis, Kerry L. Laplante, Woodmansee

Pharmacy Practice and Clinical Research Faculty Publications

The findings of clinical and in vitro research support the theory that infective endocarditis (IE)-causing bacteria form biofilms and that biofilms negatively affect treatment outcomes. The purpose of the present study was to quantify the biofilm formation of methicillin (meticillin)-resistant Staphylococcus aureus (MRSA) isolates obtained from patients with IE and to evaluate the in vitro activities of daptomycin and vancomycin alone and in combination with rifampin (rifampicin) or gentamicin while monitoring the isolates for the development of resistance. A high-inoculum, stationary-phase infection model of IE was used to simulate the pharmacokinetics in humans of daptomycin at 6 mg/kg of body …

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In Vitro Activities Of Telavancin And Vancomycin Against Biofilm-Producing Staphylococcus Aureus, S. Epidermidis, And Enterococcus Faecalis Strains, Kerry L. Laplante, A. Mermel

Pharmacy Practice and Clinical Research Faculty Publications

We investigated the activities of telavancin and vancomycin against biofilm-producing Staphylococcus and Enterococcus strains. At clinically attainable concentrations, telavancin was active against bacteria embedded in biofilm (minimal biofilm eradication concentration [MBEC], 0.125 to 2 μg/ml) and inhibited biofilm formation at concentrations below the MIC. Vancomycin did not demonstrate the same activity (MBEC, ≥512 μg/ml) against Staphylococcus aureus and Enterococcus faecalis. Telavancin may have a unique role in biofilm-associated infections.

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Happiness And Punishment, Jonathan Masur, John Bronsteen, Christopher Buccafusco

Articles

This Article continues our project of applying new findings in the behavioral psychology of human happiness to some of the most deeply analyzed questions in law. When a state decides how to punish criminal offenders, at least one important consideration is the amount of harm any given punishment is likely to inflict. It would be undesirable, for example, to impose greater harm on those who commit less serious crimes or to impose harm that rises to the level of cruelty. Our penal system fits punishments to crimes primarily by adjusting the size of monetary fines and the length of prison …

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Children's Mercy Hospital Annual Report 2008, Children's Mercy Hospital

Children's Mercy Annual Reports

Annual report for The Children's Mercy Hospital in Kansas City MO, a pediatric medical center.

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Ovine Progressive Pneumonia Provirus Levels Are Unaffected By The Prion 171r Allele In An Idaho Sheep Flock, Robert D. Harrington, Lynn M. Herrmann-Hoesing, Stephen N. White, Katherine I. O'Rourke, Donald P. Knowles

Zoonotics and Wildlife Disease: Publications

Selective breeding of sheep for arginine (R) at prion gene (PRNP) codon 171 confers resistance to classical scrapie. However, other effects of 171R selection are uncertain. Ovine progressive pneumonia/Maedi-Visna virus (OPPV) may infect up to 66% of a flock thus any affect of 171R selection on OPPV susceptibility or disease progression could have major impact on the sheep industry. Hypotheses that the PRNP 171R allele is 1) associated with the presence of OPPV provirus and 2) associated with higher provirus levels were tested in an Idaho ewe flock. OPPV provirus was found in 226 of 358 …

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Validation Of Use Of Rectoanal Mucosa-Associated Lymphoid Tissue For Immunohistochemical Diagnosis Of Chronic Wasting Disease In White-Tailed Deer (Odocoileus Virginianus), Delwyn Keane, Daniel Barr, Rebecca Osborn, Julie Langenberg, Katherine I. O'Rourke, David Schneider, Phillip Bochsler

Zoonotics and Wildlife Disease: Publications

The examination of rectoanal mucosa-associated lymphoid tissue (RAMALT) biopsy specimens for the diagnosis of transmissible spongiform encephalopathies has been described in sheep, elk, and small numbers of mule and white-tailed deer. Previous sample numbers have been too small to validate examination of this type of tissue as a viable antemortem diagnostic test. In this study, we examined RAMALT collected postmortem from 76 white-tailed deer removed from a farm in Wisconsin known to be affected by chronic wasting disease (CWD) and from 210 free-ranging white-tailed deer harvested from an area in Wisconsin where the overall prevalence of CWD among the deer …

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Scwds Briefs: Volume 24, Number 4 (January 2009), Gary L. Doster , Editor, Scwds Briefs, Michael J. Yabsley

Southeastern Cooperative Wildlife Disease Study: Publications

Table of Contents:

HD in 2007: A Year to Remember

Ecology of AIV in Shorebirds

New USDA Brucellosis Proposal

TWS Seeks Comments on Draft Lead Policy

Unusual Eagle Death

New SCWDS Grad Students

Tennessee Director Retiring

3rd International CWD Symposium

Another SCWDS Student Award

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Finfish And Aquatic Invertebrate Pathology Resources For Now And The Future, Jan M. Spitsbergen, Vicki S. Blazer, Paul R. Bowser, Keith C. Cheng, Keith R. Cooper, Timothy K. Cooper, Salvatore Frasca Jr., David B. Groman, Claudia M. Harper, Jerry M. (Mac) Law, Gary D. Marty, Roxanna M. Smolowitz, Judy St. Leger, Douglas C. Wolf, Jeffrey C. Wolf

United States Environmental Protection Agency: Publications

Utilization of finfish and aquatic invertebrates in biomedical research and as environmental sentinels has grown dramatically in recent decades. Likewise the aquaculture of finfish and invertebrates has expanded rapidly worldwide as populations of some aquatic food species and threatened or endangered aquatic species have plummeted due to overharvesting or habitat degradation. This increasing intensive culture and use of aquatic species has heightened the importance of maintaining a sophisticated understanding of pathology of various organ systems of these diverse species. Yet, except for selected species long cultivated in aquaculture, pathology databases and the workforce of highly trained pathologists lag behind those …

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Safety Assessment Of Biotechnology Products For Potential Risk Of Food Allergy: Implications Of New Research, Maryjane K. Selgrade, Christal C. Bowman, Gregory S. Ladics, Laura Privalle, Susan A. Laessig

United States Environmental Protection Agency: Publications

Food allergy is a potential risk associated with use of transgenic proteins in crops. Currently, safety assessment involves consideration of the source of the introduced protein, in silico amino acid sequence homology comparisons to known allergens, physicochemical properties, protein abundance in the crop, and, when appropriate, specific immunoglobulin E binding studies. Recently conducted research presented at an International Life Sciences Institute/Health and Environmental Sciences Institute–hosted workshop adds to the scientific foundation for safety assessment of transgenic proteins in five areas: structure/activity, serum screening, animal models, quantitative proteomics, and basic mechanisms. A web-based tool is now available that integrates a database …

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Health Assessment Of Weddell Seals, Leptonychotes Weddellii, In Mcmurdo Sound, Antarctica, P.K. Yochem, B.S. Stewart, T.S. Gelatt, D.B. Siniff

United States Department of Commerce: Staff Publications

The demography of Weddell seals in eastern McMurdo Sound, Antarctica, has been well studied during the past three decades (e.g. Stirling 1971; Siniff et al. 1977; Testa and Siniff 1987; Hastings and Testa 1998; Gelatt et al. 2001). Detailed life-history data are available on thousands of seals tagged as pups in McMurdo Sound, making this population a rich resource for wildlife health studies because health parameters can be evaluated in the light of reproductive histories and genetic relationships of several generations of tagged seals.

Recently, evidence of exposure to diseases generally associated with domestic animals and feral wildlife has been …

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Effects Of Age, Sex And Reproductive Status On Persistent Organic Pollutant Concentrations In ‘‘Southern Resident” Killer Whales, Margaret M. Krahn, M. Bradley Hanson, Gregory Schorr, Candice K. Emmons, Douglas G. Burrows, Jennie L. Bolton, Robin W. Baird, Gina M. Ylitalo

United States Department of Commerce: Staff Publications

‘‘Southern Resident” killer whales (Orcinus orca) that comprise three fish-eating ‘‘pods” (J, K and L) were listed as ‘‘endangered” in the US and Canada following a 20% population decline between 1996 and 2001. Blubber biopsy samples from Southern Resident juveniles had statistically higher concentrations of certain persistent organic pollutants than were found for adults. Most Southern Resident killer whales, including the four juveniles, exceeded the health-effects threshold for total PCBs in marine mammal blubber. Maternal transfer of contaminants to the juveniles during rapid development of their biological systems may put these young whales at greater risk than adults …

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Identification Of Small Subunits Of Mammalian Serine Palmitoyltransferase That Confer Distinct Acyl-Coa Substrate Specificities, Gongshe Han, Sita D. Gupta, Kenneth Gable, Somashekarappa Niranjanakumari, Prasun Moitra, Florian Eichler, Robert H. Brown Jr., Jeffrey M. Harmon, Teresa M. Dunn

Uniformed Services University of the Health Sciences

Serine palmitoyltransferase (SPT) catalyzes the first committed step in sphingolipid biosynthesis. In yeast, SPT is composed of a heterodimer of 2 highly-related subunits, Lcb1p and Lcb2p, and a third subunit, Tsc3p, which increases enzyme activity markedly and is required for growth at elevated temperatures. Higher eukaryotic orthologs of Lcb1p and Lcb2p have been identified, but SPT activity is not highly correlated with coexpression of these subunits and no ortholog of Tsc3p has been identified. Here, we report the discovery of 2 proteins, ssSPTa and ssSPTb, which despite sharing no homology with Tsc3p, each substantially enhance the activity of mammalian SPT …

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Vaccines For Hantaviruses, Connie Schmaljohn

United States Army: Publications

Hantaviruses are assigned to categoriesAand C on the National Institute of Allergy and Infectious Diseases (NIAID) Priority Pathogens list and to category C on the Centers for Disease Control and Prevention (CDC) Emergency Preparedness and Response list of boterrorism agents/diseases. These rodent-borne viruses are members of the family Bunyaviridae and are transmitted to humans in aerosols of rodent excreta. There are more than 20 recognized hantaviruses, some of which are associated with one of two serious human diseases: hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). Because of the global distribution of hantaviruses, the historical association of …

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Health (Hlth), Montclair State University

Course Descriptions

No abstract provided.

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Office Of The Vice Provost For Research Annual Report - 2009, Office Of The Vice Provost For Research, East Tennessee State University

Annual Reports

No abstract provided.

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2009-2010 - College Of Pharmacy Catalog, Office Of The Registrar, East Tennessee State University

Pharmacy Academic Catalogs

No abstract provided.

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Variation Of Sequence Of Genes Encoding The Murmn Operon And Cell Wall Composition In Streptococcus Pneumoniae Strains Of Different Susceptibility Levels To Penicillin, N. Kumari, M.Y. Yusof, S.Y. Ong, M. Mansor, C.F. Le, S.D. Sekaran

Research Publications (2006 to 2010)

It has been reported that there are structural differences in the muropeptides of the cell wall in penicillin-resistant Streptococcus pneumoniae. The cell wall composition and variation of the murMN operon sequence of S. pneumoniae strains with different penicillin susceptibilities were investigated. PCR amplification and sequencing of the murM and murN genes were carried out on three selected strains of S. pneumoniae. The cell wall was then extracted and elucidated using Fourier Transfer InfraRed (FTIR) Spectroscopy, followed by proton Nuclear Magnetic Resonance (NMR) Spectroscopy. The sequences of the murM and murN genes were shown to be highly conserved while FTIR and …

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Multiplex Pcr For Simultaneous Detection Of Virulence Genes In Escherichia Coli, Kwai Lin Thong, Ke Xin Yu

Research Publications (2006 to 2010)

Diarrhea caused by Escherichia coli infection is a major cause of public health problems in developing countries. In view of the deficits and limitations of conventional methods of detecting the virulence determinants, a multiplex Polymerase Chain Reaction (PCR) assay was optimized and developed to provide an effective, rapid and specific diagnostic tool to simultaneously detect virulence genes such as heatstable toxin 1 (ST1), heat-labile toxin 1 (LT1), heat-labile toxin 2 (LT2), verotoxin1 (VT1), verotoxin 2 (VT2) and attachment and effacement (eaeA) in pathogenic E. coli. Five sets of primers targeting these six virulence genes were optimized by using postitive control …

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Bull Management And Nutrition, Julie Walker, George Perry, Russ Daly, Ken Olson

Range Beef Cow Symposium

Proper management and nutrition of bulls is essential to ensure cow/calf producers maximize reproductive efficiency and genetic improvement of the calf crop. In addition, the herd bull influences overall herd fertility more than any other single animal, and loss of fertility by a bull can cause substantial loss to a potential calf crop. Each cow produces one calf per year; however, bulls should contribute to the calf crop by 25 to 60 times via siring 25 to 60 calves. Additionally, bulls influence their daughters’ production in the cow herd. Therefore, bull selection can be the most powerful method of genetic …

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Performance Management Process Report: John Jay College Goals & Targets 2009-2010, John Jay College Of Criminal Justice

Reports and Publications from John Jay College

No abstract provided.

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The Relevance Of The International Classification Of Functioning, Disability And Health (Icf) To Mental Disorders And Their Treatment, Geoffrey M. Reed, William D. Spaulding, Lynn F. Bufka

Department of Psychology: Faculty Publications

This article examines the potential usefulness of the ICF in the treatment of mental disorders.We suggest that there is a poor fit between the nature of mental disorders and the dominant model of health care based on the treatment of acute medical illness. An overemphasis on diagnosis has contributed to a bias toward pharmacotherapy and underuse of psychological treatments for people with mental disorders. Mental disorders are more accurately conceptualized as chronic conditions, in which the person’s pattern of functioning rather than diagnosis is most important in determining what services are needed. This is particularly the case for people with …

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Full-Text Articles in Entire DC Network

Inclusion Biogenesis And Reactivation Of Persistent Chlamydia Trachomatis Requires Host Cell Sphingolipid Biosynthesis, D. Kesley Robertson, Ling Gu, Regina K. Rowe, Wandy L. Beatty

Open Access Publications

A Genomic Score Prognostic Of Outcome In Trauma Patients, J. P. Cobb, Et Al.

Open Access Publications

The Human Dimension Of Global Climate Change, Edward Cameron

UC Law Environmental Journal

Tomato Bushy Stunt Virus (Tbsv), A Versatile Platform For Polyvalent Display Of Antigenic Epitopes And Vaccine Design, Shantanu Kumar, Wendy Ochoa, Pratik Singh, Catherine Hsu, Anette Schneemann, Marianne Manchester, Mark Olson, Vijay Reddy

United States Army: Publications

American Society Of Parasitologists Newsletter, V. 31, No. 3, Winter 2009, Scott Lyell Gardner

American Society of Parasitologists: Newsletter

Biology (Bims), Montclair State University

Course Descriptions

Mathematics (Math), Montclair State University

Course Descriptions

The Convent As Cultural Conduit: Irish Matronage In Early Modern Spain, Andrea Knox

Quidditas

Evaluating Aztreonam And Ceftazidime Pharmacodynamics With Escherichia Coli In Combination With Daptomycin, Linezolid, Or Vancomycin In An In Vitro Pharmacodynamic Model, Kerry L. Laplante, Sakoulas

Pharmacy Practice and Clinical Research Faculty Publications

Activities Of Daptomycin And Vancomycin Alone And In Combination With Rifampin And Gentamicin Against Biofilm-Forming Methicillin-Resistant Staphylococcus Aureus Isolates In An Experimental Model Of Endocarditis, Kerry L. Laplante, Woodmansee

Pharmacy Practice and Clinical Research Faculty Publications

In Vitro Activities Of Telavancin And Vancomycin Against Biofilm-Producing Staphylococcus Aureus, S. Epidermidis, And Enterococcus Faecalis Strains, Kerry L. Laplante, A. Mermel

Pharmacy Practice and Clinical Research Faculty Publications

Happiness And Punishment, Jonathan Masur, John Bronsteen, Christopher Buccafusco

Articles

Children's Mercy Hospital Annual Report 2008, Children's Mercy Hospital

Children's Mercy Annual Reports

Ovine Progressive Pneumonia Provirus Levels Are Unaffected By The Prion 171r Allele In An Idaho Sheep Flock, Robert D. Harrington, Lynn M. Herrmann-Hoesing, Stephen N. White, Katherine I. O'Rourke, Donald P. Knowles

Zoonotics and Wildlife Disease: Publications

Validation Of Use Of Rectoanal Mucosa-Associated Lymphoid Tissue For Immunohistochemical Diagnosis Of Chronic Wasting Disease In White-Tailed Deer (Odocoileus Virginianus), Delwyn Keane, Daniel Barr, Rebecca Osborn, Julie Langenberg, Katherine I. O'Rourke, David Schneider, Phillip Bochsler

Zoonotics and Wildlife Disease: Publications

Scwds Briefs: Volume 24, Number 4 (January 2009), Gary L. Doster , Editor, Scwds Briefs, Michael J. Yabsley

Southeastern Cooperative Wildlife Disease Study: Publications

United States Environmental Protection Agency: Publications

Safety Assessment Of Biotechnology Products For Potential Risk Of Food Allergy: Implications Of New Research, Maryjane K. Selgrade, Christal C. Bowman, Gregory S. Ladics, Laura Privalle, Susan A. Laessig

United States Environmental Protection Agency: Publications

Health Assessment Of Weddell Seals, Leptonychotes Weddellii, In Mcmurdo Sound, Antarctica, P.K. Yochem, B.S. Stewart, T.S. Gelatt, D.B. Siniff

United States Department of Commerce: Staff Publications

Effects Of Age, Sex And Reproductive Status On Persistent Organic Pollutant Concentrations In ‘‘Southern Resident” Killer Whales, Margaret M. Krahn, M. Bradley Hanson, Gregory Schorr, Candice K. Emmons, Douglas G. Burrows, Jennie L. Bolton, Robin W. Baird, Gina M. Ylitalo

United States Department of Commerce: Staff Publications

Identification Of Small Subunits Of Mammalian Serine Palmitoyltransferase That Confer Distinct Acyl-Coa Substrate Specificities, Gongshe Han, Sita D. Gupta, Kenneth Gable, Somashekarappa Niranjanakumari, Prasun Moitra, Florian Eichler, Robert H. Brown Jr., Jeffrey M. Harmon, Teresa M. Dunn

Uniformed Services University of the Health Sciences

Vaccines For Hantaviruses, Connie Schmaljohn

United States Army: Publications

Health (Hlth), Montclair State University

Course Descriptions

Office Of The Vice Provost For Research Annual Report - 2009, Office Of The Vice Provost For Research, East Tennessee State University

Annual Reports

2009-2010 - College Of Pharmacy Catalog, Office Of The Registrar, East Tennessee State University

Pharmacy Academic Catalogs

Variation Of Sequence Of Genes Encoding The Murmn Operon And Cell Wall Composition In Streptococcus Pneumoniae Strains Of Different Susceptibility Levels To Penicillin, N. Kumari, M.Y. Yusof, S.Y. Ong, M. Mansor, C.F. Le, S.D. Sekaran

Research Publications (2006 to 2010)

Multiplex Pcr For Simultaneous Detection Of Virulence Genes In Escherichia Coli, Kwai Lin Thong, Ke Xin Yu

Research Publications (2006 to 2010)

Bull Management And Nutrition, Julie Walker, George Perry, Russ Daly, Ken Olson

Range Beef Cow Symposium

Performance Management Process Report: John Jay College Goals & Targets 2009-2010, John Jay College Of Criminal Justice

Reports and Publications from John Jay College

The Relevance Of The International Classification Of Functioning, Disability And Health (Icf) To Mental Disorders And Their Treatment, Geoffrey M. Reed, William D. Spaulding, Lynn F. Bufka

Department of Psychology: Faculty Publications