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2009

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Hope (Health Of Prisoner Evaluation): Pilot Study Of Prisoner Physical Health And Psychological Wellbeing, Sharan Kraemer, Natalie Gately, Jenny Kessell Jan 2009

Hope (Health Of Prisoner Evaluation): Pilot Study Of Prisoner Physical Health And Psychological Wellbeing, Sharan Kraemer, Natalie Gately, Jenny Kessell

Research outputs pre 2011

Prisons offer a unique opportunity to make positive interventions not only in relation to health issues but also to address the social determinants of ill health. Even with the limited knowledge we have had in regard to the health of WA's prisoners it is apparent that prisons concentrate patients with significantly greater levels of morbidity than most other environments. It is also apparent that this concentration of morbidity parallels deficits in housing, nutrition, employment, education and family structure and is multiplied dramatically by the blight of mental illness and drug and alcohol abuse. Western Australia is unequalled in the Western …


Digital Research Cycles: How Attitudes Toward Content, Culture And Technology Affect Web Development., Edward Scott Jan 2009

Digital Research Cycles: How Attitudes Toward Content, Culture And Technology Affect Web Development., Edward Scott

Electronic Theses and Dissertations

It has been estimated that one third of the world's population does not have access to "adequate" health care. Some 1.6 billion people live in countries experiencing "concentrated" acquired immune deficiency syndrome (AIDS) epidemics. Many countries in Africa--and other low-income countries--are in dire need of help providing adequate health care services to their citizens. They require more hands-on care from Western health workers--and training so more African health workers can eventually care for their own citizens. But these countries also need assistance acquiring and implementing both texts--the body of medical information potentially available to them--and technology--the means by which that …


Novel Cell-Based Method To Detect Shiga Toxin 2 From Escherichia Coli O157: H7 And Inhibitors Of Toxin Activity, Beatriz Quiñones, Shane Massey, Mendel Friedman, Michelle S. Swimley, Ken Teter Jan 2009

Novel Cell-Based Method To Detect Shiga Toxin 2 From Escherichia Coli O157: H7 And Inhibitors Of Toxin Activity, Beatriz Quiñones, Shane Massey, Mendel Friedman, Michelle S. Swimley, Ken Teter

Faculty Bibliography 2000s

Escherichia coli O157: H7 is a leading cause of food-borne illness. This human pathogen produces Shiga toxins (Stx1 and Stx2) which inhibit protein synthesis by inactivating ribosome function. The present study describes a novel cell-based assay to detect Stx2 and inhibitors of toxin activity. A Vero cell line harboring a destabilized variant (half- life, 2 h) of the enhanced green fluorescent protein (d2EGFP) was used to monitor the toxin-induced inhibition of protein synthesis. This Vero-d2EGFP cell line produced a fluorescent signal which could be detected by microscopy or with a plate reader. However, a greatly attenuated fluorescent signal was detected …


Iron In Arterial Plaque: A Modifiable Risk Factor For Atherosclerosis, Jerome L. Sullivan Jan 2009

Iron In Arterial Plaque: A Modifiable Risk Factor For Atherosclerosis, Jerome L. Sullivan

Faculty Bibliography 2000s

It has been proposed that iron depletion protects against cardiovascular disease. There is increasing evidence that one mechanism for this protection may involve a reduction in iron levels within atherosclerotic plaque. Large increases in iron concentration are seen in human atherosclerotic lesions in comparison to levels in healthy arterial tissue. In animal models, depletion of lesion iron levels in vivo by phlebotomy, systemic iron chelation treatment or dietary iron restriction reduces lesion size and/or increases plaque stability. A number of factors associated with increased arterial disease or increased cardiovascular events is also associated with increased plaque iron. In rats, infusion …


In Step With Hiv Vaccines? A Content Analysis Of Local Recruitment Campaigns For An International Hiv Vaccine Study, Paula M. Frew, Wendy Macias, Kayshin Chan, Ashley Harding Jan 2009

In Step With Hiv Vaccines? A Content Analysis Of Local Recruitment Campaigns For An International Hiv Vaccine Study, Paula M. Frew, Wendy Macias, Kayshin Chan, Ashley Harding

Environmental & Global Health Faculty Research

During the past two decades of the HIV/AIDS pandemic, several recruitment campaigns were designed to generate community involvement in preventive HIV vaccine clinical trials. These efforts utilized a blend of advertising and marketing strategies mixed with public relations and community education approaches to attract potential study participants to clinical trials (integrated marketing communications). Although more than 30,000 persons worldwide have participated in preventive HIV vaccine studies, no systematic analysis of recruitment campaigns exists. This content analysis study was conducted to examine several United States and Canadian recruitment campaigns for one of the largest-scale HIV vaccine trials to date (the “Step …


Comparison Of Clinical And Histopathologic Findings Of Pathergy Test With Disposable/Sharp And Nondisposable/Blunt Needles In Behcet´S Disease, Ayşe Serap Karadağ, Gülfer Akbay, Mehtap Aydin, Hesna Müzeyyen Astarci, Meral Ekşi̇oğlu Jan 2009

Comparison Of Clinical And Histopathologic Findings Of Pathergy Test With Disposable/Sharp And Nondisposable/Blunt Needles In Behcet´S Disease, Ayşe Serap Karadağ, Gülfer Akbay, Mehtap Aydin, Hesna Müzeyyen Astarci, Meral Ekşi̇oğlu

Turkish Journal of Medical Sciences

Aim: The aim of this study was to determine whether using blunt instead of sharp needles presented any advantage and whether the histopathological interpretation prevailed over the clinical interpretation. Materials and Methods: This study was performed on 60 Behçet´s disease (BD) patients and 20 control subjects. The pathergy test was applied to all subjects intradermally with sharp and blunt needles and the histopathology of each test result was studied. Results: In the active period of BD (40 patients), positive test results were obtained in 34 (85.0%) patients using blunt needles and in 13 (32.5%) using sharp needles (P = 0.0001). …


Comparison Of Gliclazide Treatment With Diet Therapy On Acute Phase Protein Levels In Patients With Type 2 Diabetes, Ramazan Memi̇şoğullari, Fati̇h Akçay, Abdurrahman Coşkun, Uğur Korkmaz Jan 2009

Comparison Of Gliclazide Treatment With Diet Therapy On Acute Phase Protein Levels In Patients With Type 2 Diabetes, Ramazan Memi̇şoğullari, Fati̇h Akçay, Abdurrahman Coşkun, Uğur Korkmaz

Turkish Journal of Medical Sciences

Aims: It is known that there is a relationship between diabetic complications and chronic inflammation characterized by alterations in circulating acute phase proteins. It has been emphasized that inflammation contributes to diabetic complications and that gliclazide -an antidiabetic sulfonylurea - decreases the development of such complications. In this study, we aimed to investigate whether gliclazide or diet treatment has an effect on serum levels of acute phase reactants, markers of inflammation. Materials and Methods: Fifty-six newly diagnosed patients with type 2 diabetes and 30 clinically healthy subjects were evaluated prospectively. Twenty-six patients were treated with proper diet and daily gliclazide …


Recurrent Breast Abscess Caused By Corynebacterium Amycolatum And Rewiev Of The Literature, İsmet Özaydin, Mustafa Yildirim, İdri̇s Şahi̇n, Sami̇ Doğan Jan 2009

Recurrent Breast Abscess Caused By Corynebacterium Amycolatum And Rewiev Of The Literature, İsmet Özaydin, Mustafa Yildirim, İdri̇s Şahi̇n, Sami̇ Doğan

Turkish Journal of Medical Sciences

Corynebacterium species are an uncommon cause of breast abscess, and Corynebacterium amycolatum is rarely described in the literature. In the present case, we report recurrent breast abscess caused by C. amycolatum in a 39-year-old patient with normal immune function. Pathological diagnosis was granulomatous mastitis. The patient was treated with incision and drainage and ampicillin-sulbactam treatment. To our knowledge, this is the second report of breast abscess caused by C. amycolatum.


Investigation (In Vivo And In Vitro) Of Booster Dose Vaccine Requirement For Long-Term Protection Against Hepatitis B Virus Infection, Onur Saygun, Can Polat Eyi̇gün, İsmai̇l Yaşar Avci, Üçler Kisa, Alaaddi̇n Pahsa Jan 2009

Investigation (In Vivo And In Vitro) Of Booster Dose Vaccine Requirement For Long-Term Protection Against Hepatitis B Virus Infection, Onur Saygun, Can Polat Eyi̇gün, İsmai̇l Yaşar Avci, Üçler Kisa, Alaaddi̇n Pahsa

Turkish Journal of Medical Sciences

Aim: Studies have shown that no booster dose was required at least 10 to 15 years after a primary vaccination for individuals who developed protective anti-hepatitis B surface (anti-HBs) antibodies. In this study, booster dose requirement for HBV after primary immunization was investigated. Materials and Methods: Seventeen individuals vaccinated previously were enrolled in the study. They had once developed a protective level of anti-HBs antibody after immunization and their anti-HBs titer had declined to an underprotective level. Twenty uninfected and unvaccinated healthy people were chosen as controls. Lymphoproliferative response to in-vitro stimulation with hepatitis B surface antigen (HBsAg) and anti-HBs …


The Epidemiology Of Microsporidias In Humans (Malatya Sample), Ülkü Karaman, Ni̇lgün Daldal, Meti̇n Atambay, Cemi̇l Çolak Jan 2009

The Epidemiology Of Microsporidias In Humans (Malatya Sample), Ülkü Karaman, Ni̇lgün Daldal, Meti̇n Atambay, Cemi̇l Çolak

Turkish Journal of Medical Sciences

Aim: Microsporidias, first isolated and defined in 1857, are obligate intracellular parasites observed in animal groups and especially invertebrates. Generally homosexual patients and patients who are HIV positive and immune suppressed constitute the participants of international studies about the epidemiology of microsporidias. No previous studies about the prevalence of the parasite in Turkey have been found in the literature. This study aimed to determine the epidemiology of microsporidias in and around Malatya. Materials and Methods: Feces samples (n: 2665) from patients who presented at İnönü University Medical Faculty policlinics in 2006 with some digestive system complaints and were referred to …


The Problem Of Antimicrobial Resistance In Nosocomial Medical And Surgical Intensive Care Units Infections In A University Hospital; A Two-Year Prospective Study, Şaban İnceci̇k, Neşe Saltoğlu, Akgün Yaman, İbrahi̇m Karayaylali, Mehmet Özalevli̇, Murat Gündüz, Refi̇k Burgut Jan 2009

The Problem Of Antimicrobial Resistance In Nosocomial Medical And Surgical Intensive Care Units Infections In A University Hospital; A Two-Year Prospective Study, Şaban İnceci̇k, Neşe Saltoğlu, Akgün Yaman, İbrahi̇m Karayaylali, Mehmet Özalevli̇, Murat Gündüz, Refi̇k Burgut

Turkish Journal of Medical Sciences

Aim: To determine the frequency of nosocomial infections (NIs) and the antimicrobial resistance of pathogens isolated from patients admitted to 4 intensive care units (ICUs) at a university hospital. Materials and Methods: The patients were prospectively followed over 2 years in medical, surgical, and reanimation ICUs. The isolates were collected from patients with NI determined by the Center for Diseases Control and Prevention criteria. The identification was performed and susceptibility to antibiotics was determined in an automated system Sceptor (Becton Dickinson) as described by the CCLS. Results: Among the 3962 patients in the ICUs, total NI incidence was 6.9%, with …


Disseminated Herpes Zoster Infection In A Patient With Lymphoma, Behi̇ce Kurtaran, Semra Paydaş, Aslihan Candevi̇r, Süheyla Kömür, Hasan Sali̇h Zeki̇ Aksu Jan 2009

Disseminated Herpes Zoster Infection In A Patient With Lymphoma, Behi̇ce Kurtaran, Semra Paydaş, Aslihan Candevi̇r, Süheyla Kömür, Hasan Sali̇h Zeki̇ Aksu

Turkish Journal of Medical Sciences

Immunosuppression facilitates varicella zoster virus (VZV) reactivation in immunocompromised patients. Atypical presentation such as disseminated disease of herpes zoster infection has been described in immunosuppressed patients. One of the best choices of therapy in herpes zoster infection is acyclovir, but long-term therapy may cause resistance to it. In this report a disseminated herpes zoster infection is described in a patient with T cell lymphoma after acyclovir/valacyclovir therapy. The infection was irresponsive to acyclovir and valacyclovir and we were unable to control the infection because it was not possible to obtain foscarnet and the patient died due to Staphylococcus epidermis sepsis.


Cefoperazone-Sulbactam Plus Amikacin Empirical Therapy For Febrile Neutropenia In Children With Cancer, İbrahi̇m Bayram, Fati̇h Erbey, Derya Alabaz, Sema Yilmaz, Ati̇la Tanyeli̇ Jan 2009

Cefoperazone-Sulbactam Plus Amikacin Empirical Therapy For Febrile Neutropenia In Children With Cancer, İbrahi̇m Bayram, Fati̇h Erbey, Derya Alabaz, Sema Yilmaz, Ati̇la Tanyeli̇

Turkish Journal of Medical Sciences

Aim: To determine the efficacy and safety of cefoperazone-sulbactam combined with amikacin in the treatment of febrile neutropenia in children with cancer. Materials and Methods: The study included 20 cancer cases with 26 febrile neutropenia (FEN) episodes. Patient selection criteria were defined according to the guidelines issued by the Infectious Disease Society of America (IDSA). Results: Patients diagnosed with acute leukemia (58%) and solid tumors (42%) were recorded. Twelve (46.2%) of the primary disease cases were refractory. The number of infection episodes identified microbiologically and clinically was 10 (38.5%) and 12 (46.1%), respectively. Fever of unknown origin was observed in …


An Analysis Of Adult Patients With Pulmonary And Extrapulmonary Tuberculosis*, Aygün Öztop, İpek Ünsal, Türkan Günay, Vi̇ldan Avkan Oğuz, Riza Çakmak Jan 2009

An Analysis Of Adult Patients With Pulmonary And Extrapulmonary Tuberculosis*, Aygün Öztop, İpek Ünsal, Türkan Günay, Vi̇ldan Avkan Oğuz, Riza Çakmak

Turkish Journal of Medical Sciences

Aim: In this study, it was planned to compare the features of pulmonary and extra-pulmonary tuberculosis patients over age 15 years. Materials and methods: We compared 360 newly diagnosed pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) patients who were treated and followed up in Kahramanlar Tuberculosis Dispensary between 2000 and 2003, and were older than 15 years of age. The medical records of both patient groups were investigated in terms of age, sex, accompanying diseases, contact history and means of diagnosis. Results: The data were compared statistically between the 2 groups. Of these patients 78.1% were diagnosed with PTB while …


Epidemiological Risk Factors For Crimean-Congo Hemorrhagic Fever Patients, Ayten Kadanali, Serpi̇l Erol, Zülal Özkurt, Kemaletti̇n Özden Jan 2009

Epidemiological Risk Factors For Crimean-Congo Hemorrhagic Fever Patients, Ayten Kadanali, Serpi̇l Erol, Zülal Özkurt, Kemaletti̇n Özden

Turkish Journal of Medical Sciences

Aim The aim of this study was to evaluate the epidemiological risk factors for Crimean-Congo hemorrhagic fever (CCHF) patients admitted to our hospitals between January 2004- December 2006. Materials and methods: This was a study of 63 CCHF patients whose definitive diagnosis was based on the detection of CCHF virus-specific IgM by ELISA and/or of genomic segments of the CCHF virus by real time polymerase chain reaction (RT-PCR) and 50 healthy controls. Related data were collected prospectively. Results: Twenty-two (50.8%) of the patients were female, and 31 of them (49.2%) were male. The mean age of the patients was 46 …


The Predictive Role Of Ast Level, Prothrombin Time, And Platelet Count In The Detection Of Liver Fibrosis In Patients With Chronic Hepatitis C, Özlem Kandemi̇r, Gürbüz Polat, Güli̇z Saraçoğlu, Bahar Taşdelen Jan 2009

The Predictive Role Of Ast Level, Prothrombin Time, And Platelet Count In The Detection Of Liver Fibrosis In Patients With Chronic Hepatitis C, Özlem Kandemi̇r, Gürbüz Polat, Güli̇z Saraçoğlu, Bahar Taşdelen

Turkish Journal of Medical Sciences

Aim: We aimed to assess the predictive value of a combination some of basic serum biochemical markers for the diagnosis of clinically significant fibrosis in chronic hepatitis C. Materials and methods: Blood samples from 68 patients with chronic hepatitis C infection were analyzed for aspartate aminotransferase, prothrombin INR, and platelet count. The liver histopathology was evaluated using the Knodell protocol. The relationship between the serum biochemical markers and severity of the stages were examined. Results: A strong association was found between the fibrosis stage and platelet count and GUCI (P < 0.001, P = 0.035 respectively) but not APRI ([AST/ULN] / Platelet count [ ×109 /L]) × 100) (P = 0.052). The relationship between the platelet count


Competing Interests And Gamete Donation: The Case For Anonymity, Julie L. Sauer Jan 2009

Competing Interests And Gamete Donation: The Case For Anonymity, Julie L. Sauer

Seton Hall Law Review

No abstract provided.


Clinical Research In A Public Health Crisis: The Integrative Approach To Managing Uncertainty And Mitigating Conflict, Alex John London Jan 2009

Clinical Research In A Public Health Crisis: The Integrative Approach To Managing Uncertainty And Mitigating Conflict, Alex John London

Seton Hall Law Review

No abstract provided.


Kss 2136 : Athletic Training As A Profession, Kinesiology And Sports Studies Jan 2009

Kss 2136 : Athletic Training As A Profession, Kinesiology And Sports Studies

Approved Course Proposals

No abstract provided.


Patent Breaking Or Balancing?: Separating Strands Of Fact From Fiction Under Trips., Cynthia M. Ho Jan 2009

Patent Breaking Or Balancing?: Separating Strands Of Fact From Fiction Under Trips., Cynthia M. Ho

Faculty Publications & Other Works

This article provides the first comprehensive analysis of when compulsory licensing of patents is permissible as a matter of international law under the Agreement of Trade-Related Aspects of Intellectual Property TRIPS).Thailand's recent compulsory licenses of patents on a variety of medications provide a convenient vehicle to analyze the limits of compulsory licensing under TRIPS. Thailand's actions are unique; most countries hesitate to issue compulsory licenses in the wake of legal uncertainties regarding TRIPS requirements as well as political pressure. This article capitalizes on the many issues involved in Thailand's licenses to provide an authoritative interpretation of the scope of compulsory …


Unveiling Competing Patent Perspectives Ho 2009 Unveiling Competing Patent Perspectives, 46 Hous. L. Rev. 1047 (2009), Cynthia M. Ho Jan 2009

Unveiling Competing Patent Perspectives Ho 2009 Unveiling Competing Patent Perspectives, 46 Hous. L. Rev. 1047 (2009), Cynthia M. Ho

Faculty Publications & Other Works

No abstract provided.


Happiness And Punishment., John Bronsteen Jan 2009

Happiness And Punishment., John Bronsteen

Faculty Publications & Other Works

No abstract provided.


Electroporation For The Delivery Of Dna-Based Vaccines And Immunotherapeutics: Current Clinical Developments, Angela M. Bodles-Brakhop, Richard Heller, Ruxandra Draghia-Akli Jan 2009

Electroporation For The Delivery Of Dna-Based Vaccines And Immunotherapeutics: Current Clinical Developments, Angela M. Bodles-Brakhop, Richard Heller, Ruxandra Draghia-Akli

Bioelectrics Publications

Electroporation (EP) has been used in basic research for the past 25 years to aid in the transfer of DNA into cells in vitro. EP in vivo enhances transfer of DNA vaccines and therapeutic plasmids to the skin, muscle, tumors, and other tissues resulting in high levels of expression, often with serological and clinical benefits. the recent interest in nonviral gene transfer as treatment options for a vast array of conditions has resulted in the refinement and optimization of EP technology. current research has revealed that EP can be successfully used in many species, including humans. clinical trials are …


The Coming Transformation: Values To Sustain Human And Natural Communities, Stephen R. Kellert, James Gustave Speth Jan 2009

The Coming Transformation: Values To Sustain Human And Natural Communities, Stephen R. Kellert, James Gustave Speth

Yale School of the Environment Publications Series

No abstract provided.


Medicine@Yale May/June 2009 Volume 5, Issue 3, Yale School Of Medicine Office Of Communications Jan 2009

Medicine@Yale May/June 2009 Volume 5, Issue 3, Yale School Of Medicine Office Of Communications

Medicine@Yale - development newsletter

Medicine@Yale : advancing biomedical science, education and health care was a print and online newsletter which published news about academics, research and philanthropy for alumni, donors, faculty, students and the general public. It was initially published 6 times a year and then changed to a quarterly schedule. The first issue came out June/Jul. 2005. The final issue was published in May/June 2022, vol. 17, issue 1. Published by Yale School of Medicine, Office of Communications.


Medicine@Yale March/April 2009 Volume 5, Issue 2, Yale School Of Medicine Office Of Communications Jan 2009

Medicine@Yale March/April 2009 Volume 5, Issue 2, Yale School Of Medicine Office Of Communications

Medicine@Yale - development newsletter

Medicine@Yale : advancing biomedical science, education and health care was a print and online newsletter which published news about academics, research and philanthropy for alumni, donors, faculty, students and the general public. It was initially published 6 times a year and then changed to a quarterly schedule. The first issue came out June/Jul. 2005. The final issue was published in May/June 2022, vol. 17, issue 1. Published by Yale School of Medicine, Office of Communications.


Altruism And Intermediation In The Market For Babies, Kimberly D. Krawiec Jan 2009

Altruism And Intermediation In The Market For Babies, Kimberly D. Krawiec

Washington and Lee Law Review

Central to every legal system is the principle that certain items are offlimits to commercial exchange. In theory, babies are one such sacred object. This supposed ban on baby selling has been lamented by those who view commercial markets as the most efficient means of allocating resources, and defended by those who contend that commercial markets in parental rights commodify human beings, compromise individual dignity, or jeopardize fundamental values. However, the supposed and much-discussed baby selling ban does not, and is not intended to, eliminate commercial transactions in children. Instead, it is an asymmetric legal restriction that limits the ability …


The Refugee Experience: A Legal Examination Of The Immigrant Experiences Of The Sudanese Population, Kathleen Anne Ward-Lambert Jan 2009

The Refugee Experience: A Legal Examination Of The Immigrant Experiences Of The Sudanese Population, Kathleen Anne Ward-Lambert

Nova Law Review

No abstract provided.


When Did The Ancestors Of Polynesia Begin To Migrate To Polynesia? The Mtdna Evidence, David Lesniewski Jan 2009

When Did The Ancestors Of Polynesia Begin To Migrate To Polynesia? The Mtdna Evidence, David Lesniewski

UNLV Theses, Dissertations, Professional Papers, and Capstones

The timing and nature of the migration of the ancestors of the Polynesian people is debated by two competing theories. The "Express Train" and "Slow Boat" theories assert that the migration of the Proto-Polynesian people began around 6,000 years before present (BP) or around 10,000 years BP respectively. Through the use of haplogroups and specific genetic mutations a direct relationship between the Proto-Polynesians and modern Polynesians was attempted to test which of these theories was correct. The ancient skeletal remains from the island of Borneo currently housed at UNLV were used in this study as their dates fall within both …


Protection Of Macrophages J774a.1 By Purine Nucleoside Analogues From Bacillus Anthracis Mediated Necrosis, Zadkiel R. Alvarez Jan 2009

Protection Of Macrophages J774a.1 By Purine Nucleoside Analogues From Bacillus Anthracis Mediated Necrosis, Zadkiel R. Alvarez

UNLV Theses, Dissertations, Professional Papers, and Capstones

Eight years after the lamentable anthrax attacks, major scientific effort continues to be done, in order to stop imminent acts of bioterrorism. Innovative ways of therapy against the anthrax disease are being investigated. B. anthracis, the etiological agent of the infection, has a dormant stage in its life cycle known as the endospore. When conditions become favorable spores germinate, transforming into vegetative bacteria. In inhalational anthrax, the most fatal manifestation of the disease, spores enter the organism through the respiratory track, and are phagocytosized by alveolar macrophages of the lungs. Spores are able to sense nutrient availability, activating their germination …