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Articles 32251 - 32280 of 32302
Full-Text Articles in Entire DC Network
Seven Things The New Epa Administrator Should Do, Michael B. Gerrard
Seven Things The New Epa Administrator Should Do, Michael B. Gerrard
Faculty Scholarship
In view of the dramatic shift in the nation's environmental policy that is presaged by the ascension of Barack Obama, I have been asked to suggest several actions that should be undertaken by the new administrator of the Environmental Protection Agency (EPA).
This article was written on Jan. 26, 2009, six days after the inauguration. It is to appear in March. Thus every reader will know something that, today, I don't – what long-pent-up actions were taken by President Obama shortly after he moved into the Oval Office. But I am guessing that by the time this article appears, Lisa …
Integration, Reconstructed, Olatunde C.A. Johnson
Integration, Reconstructed, Olatunde C.A. Johnson
Faculty Scholarship
This article examines Parents Involved for the light it sheds on integration's continuing relevance to educational and social equity. Part I examines the story of school integration in Jefferson County and shows how this largely successful metropolitan integration plan challenges claims of racial integration's futility. Part II puts forward the empirical evidence that plaintiffs in Parents Involved used in seeking to establish that school boards have a compelling interest in promoting racial integration and avoiding the harm of racially isolated schools. This part argues that the empirical case for racial integration, while not without limitations, moves beyond stigmatization, psychological harm, …
Into The Void: Governing Finance In Central & Eastern Europe, Katharina Pistor
Into The Void: Governing Finance In Central & Eastern Europe, Katharina Pistor
Faculty Scholarship
Twenty years after the fall of the iron curtain, which for decades had separated East from West, many countries of Central and Eastern Europe (CEE) are now members of the European Union and some have even adopted the Euro. Their readiness to open their borders to foreign capital and their faith in the viability of market self-governance as well as supra-national governance of finance is both remarkable and almost unprecedented. The eagerness of the countries in CEE to join the West and to become part of a regional and global regime as a way of escaping their closeted socialist past …
The Guinea Pig Ileum Lacks The Direct, High-Potency, M2-Muscarinic, Contractile Mechanism Of The Mouse Ileum, Michael T. Griffin, Minoru Matsui, Rennolds S. Ostrom, Frederick J. Ehlert
The Guinea Pig Ileum Lacks The Direct, High-Potency, M2-Muscarinic, Contractile Mechanism Of The Mouse Ileum, Michael T. Griffin, Minoru Matsui, Rennolds S. Ostrom, Frederick J. Ehlert
Pharmacy Faculty Articles and Research
We explored whether the M2 muscarinic receptor in the guinea pig ileum elicits a highly potent, direct-contractile response, like that from the M3 muscarinic receptor knockout mouse. First, we characterized the irreversible receptor-blocking activity of 4-DAMP mustard in ileum from muscarinic receptor knockout mice to verify its M3 selectivity. Then, we used 4-DAMP mustard to inactivate M3 responses in the guinea pig ileum to attempt to reveal direct, M2 receptor-mediated contractions. The muscarinic agonist, oxotremorine-M, elicited potent contractions in ileum from wild-type, M2 receptor knockout, and M3 receptor knockout mice characterized by negative log EC50 (pEC50) values ± SEM of …
Differential Ligand Binding To A Human Cytomegalovirus Chemokine Receptor Determines Cell Type-Specific Motility, Jennifer Totonchy, Ryan Melnychuk, Patricia P. Smith, Joshua Powell, Laurel Hall, Victor R. Defilippis, Klaus Fruh, Martine Smit, David D. Schlaepfer, Jay A. Nelson, Daniel N. Streblow
Differential Ligand Binding To A Human Cytomegalovirus Chemokine Receptor Determines Cell Type-Specific Motility, Jennifer Totonchy, Ryan Melnychuk, Patricia P. Smith, Joshua Powell, Laurel Hall, Victor R. Defilippis, Klaus Fruh, Martine Smit, David D. Schlaepfer, Jay A. Nelson, Daniel N. Streblow
Pharmacy Faculty Articles and Research
While most chemokine receptors fail to cross the chemokine class boundary with respect to the ligands that they bind, the human cytomegalovirus (HCMV)-encoded chemokine receptor US28 binds multiple CC-chemokines and the CX3Cchemokine Fractalkine. US28 binding to CC-chemokines is both necessary and sufficient to induce vascular smooth muscle cell (SMC) migration in response to HCMV infection. However, the function of Fractalkine binding to US28 is unknown. In this report, we demonstrate that Fractalkine binding to US28 not only induces migration of macrophages but also acts to inhibit RANTES-mediated SMC migration. Similarly, RANTES inhibits Fractalkine-mediated US28 migration in macrophages. While US28 binding …
Effect Of The Regiochemistry Of Butyl Amide Substituents On The Solution-State Structures Of Lanthanide(Iii) Dota-Tetraamide Complexes, Tomoyasu Mani, Gyula Tircsó, Piyu Zhao, A. Dean Sherry, Mark Woods
Effect Of The Regiochemistry Of Butyl Amide Substituents On The Solution-State Structures Of Lanthanide(Iii) Dota-Tetraamide Complexes, Tomoyasu Mani, Gyula Tircsó, Piyu Zhao, A. Dean Sherry, Mark Woods
Chemistry Faculty Publications and Presentations
The coordination geometry adopted by the lanthanide complexes of DOTA-tetraamides is a critical factor in determining their water exchange kinetics. Controlling the water exchange kinetics of DOTA-tetraamide complexes, and by extension their coordination geometry, is of particular interest because of the potential application of this class of complex as PARACEST MRI contrast agents. To facilitate the maximum CEST effect at the lowest pre-saturation powers much slower exchange kinetics are required than are commonly observed with these types of chelates. Complexes that adopt the more slowly exchanging square antiprismatic coordination geometry are therefore preferred; however, the factors that govern which coordination …
Exploring The Ph Dependence Of Viologen Reduction By Alpha-Carbon Radicals Derived From Hcy And Cys, Dong Wang, William E. Crowe, Robert M. Strongin, Martha Sibrian-Vazquez
Exploring The Ph Dependence Of Viologen Reduction By Alpha-Carbon Radicals Derived From Hcy And Cys, Dong Wang, William E. Crowe, Robert M. Strongin, Martha Sibrian-Vazquez
Chemistry Faculty Publications and Presentations
The colorimetric reaction of homocysteine (HCy) with a series of viologen salts suggests a linear correlation between the mid-point reduction potential of Hcy-derived α-carbon radicals and pH.
Optimising The Synthesis And Red–Green–Blue Emission Of A Simple Organic Dye, Martha Sibrian-Vazquez, Robert M. Strongin
Optimising The Synthesis And Red–Green–Blue Emission Of A Simple Organic Dye, Martha Sibrian-Vazquez, Robert M. Strongin
Chemistry Faculty Publications and Presentations
Synthetic dyes have been widely used in supramolecular chemistry not only to probe fundamental chemical interactions but also as components of functional materials. Most current efforts in this regard are directed at designing new host systems for the dyes. Herein we report on the study of a versatile new organic fluorophore. We describe a synthesis which affords improved yields in a convenient one pot procedure. Moreover, a simple method for predicting and controlling the dye’s responses to external stimuli affords a potentially practical method for achieving red–green–blue and concomitant white light generation.
Abolishing The Time Tax On Voting, Elora Mukherjee
Abolishing The Time Tax On Voting, Elora Mukherjee
Faculty Scholarship
A “time tax” is a government policy or practice that forces one citizen to pay more in time to vote compared with her fellow citizens. While few have noticed the scope of the problem, data indicate that, due primarily to long lines, hundreds of thousands if not millions of voters are routinely unable to vote in national elections as a result of the time tax, and that the problem disproportionately affects minority voters and voters in the South. This Article documents the problem and offers a roadmap for legal and political strategies for solving it. The Article uses as a …
Raising The Cut-Off: The Empirical Case For Extending Adoption And Guardianship Subsidies From Age 18 To 21, Mary Eschelbach Hansen, Joshua Gupta-Kagan
Raising The Cut-Off: The Empirical Case For Extending Adoption And Guardianship Subsidies From Age 18 To 21, Mary Eschelbach Hansen, Joshua Gupta-Kagan
Faculty Scholarship
This article begins with the context: despite increases in the number of adoptions from foster care achieved in the 1990s, tens of thousands of children remain in foster care awaiting adoption or permanent guardianship. The following section provides background on subsidy law and policy. The section describes the recent history of federal and state subsidies for parents who adopt children from the state foster care systems; the section describes state subsidies for caregivers who become legal permanent guardians of children in the state child welfare systems, and the section describes the disparities between adoption and guardianship subsidies and the subsidies …
Coal-Fired Powerplants Dominate Climate Change Litigation, Michael B. Gerrard
Coal-Fired Powerplants Dominate Climate Change Litigation, Michael B. Gerrard
Faculty Scholarship
Litigation aiming to reduce emissions of greenhouse gases (GHGs) is coming to be dominated by battles over coal-fired power plants. Ten of the last 20 judicial or administrative decisions or case filings in matters aiming to reduce GHGs have concerned such plants. A concerted effort by the environmental community to fight the use of coal is behind much of this litigation. According to the Energy Information Administration, the combustion of coal is the largest source of GHG emissions in the United States; motor vehicles are a not-very-close second.
The Sierra Club has a Web site that tracks all the proposed …
The Obama Administration's First Environmental Policy Changes, Michael B. Gerrard
The Obama Administration's First Environmental Policy Changes, Michael B. Gerrard
Faculty Scholarship
Under President Clinton the U.S. EPA took the position that it had the authority to regulate greenhouse gases (GHGs) from motor vehicles under the Clean Air Act as written, but the Clinton administration did not take affirmative steps to actually employ that authority. When President Bush took office, the General Counsel of EPA took the opposite position, stating that it would need special authorizing legislation in order to architect that regulation. A petition was filed with the EPA by the International Council for Technology Assessment and other organizations asking EPA to impose such regulations. EPA denied the petition. This led …
Environmental Law In 2049: A Look Back, Michael B. Gerrard
Environmental Law In 2049: A Look Back, Michael B. Gerrard
Faculty Scholarship
December 22 marks the 40th anniversary of the National Environmental Policy Act, which started the modern era of environmental law, and the 40th anniversary of the Environmental Law Institute, which was founded to monitor the new field and to create a profession around the emerging discipline. To mark this anniversary, we asked a range of luminaries to forecast how environmental law and the profession dedicated to its successful implementation will mature over the next four decades. Will environmental protection still be the product of a social movement, or will it have become incorporated as part of the cost of doing …
2009 Writing Contest Winners, State University Of New York At Cortland
2009 Writing Contest Winners, State University Of New York At Cortland
Transformations
The Writing Contest is sponsored by the College Writing Committee and is presented during Transformations conference (formally titled Scholar's Day) at SUNY Cortland.
A Few Questions About The Social-Obligation Norm, Jedediah S. Purdy
A Few Questions About The Social-Obligation Norm, Jedediah S. Purdy
Faculty Scholarship
I applaud Gregory Alexander for proposing an innovative view of property, one focused on the obligations of ownership. His project locates what I think of as the liberal aim of personal freedom (meaning both formal autonomy and real opportunity) within a social context of distributive choices and conceptions of mutual obligation. That is, he is asking what counts as a free society, and he is putting property regimes at the center of the answer. I want to set out some questions about where his project goes from here.
Tax Policy Challenges, Michael J. Graetz
Tax Policy Challenges, Michael J. Graetz
Faculty Scholarship
In 1995, when the late, great Jack Nolan asked me to deliver the inaugural lecture in honor of Larry Woodworth, I was both honored and flattered. I had come to know Larry Woodworth beginning in 1969, when I was a rookie treasury tax policy staffer. At that time, he had already served the Joint Committee on Taxation for 25 years and had been the third Chief of Staff in its history beginning as chief of staff in 1964. Larry Woodworth was not only as knowledgeable about the tax law as anyone you would ever hope to meet, and as savvy …
Hands Off: When And About What, Kent Greenawalt
Hands Off: When And About What, Kent Greenawalt
Faculty Scholarship
I was very pleased to have the chance to comment on these four thoughtful and challenging papers when they were delivered orally at the Association of American Law Schools (AALS) Convention in January, and I am glad to have the opportunity to share some of my unsystematic thoughts about their published versions. I begin with two general observations before addressing the individual essays in turn.
When I came up with the phrase "Hands Off' to liven the title of my article on judicial resolutions of property disputes generated by splits in religious groups, I had not reflected on the wide …
The Cultural Defense: Reflections In Light Of The Model Penal Code And The Religious Freedom Restoration Act, Kent Greenawalt
The Cultural Defense: Reflections In Light Of The Model Penal Code And The Religious Freedom Restoration Act, Kent Greenawalt
Faculty Scholarship
I wrote this essay after participating in a 2006 workshop on Criminal Law and Cultural Diversity, which discussed, among other subjects, the wisdom of providing a "cultural defense." Uncertain just how far such a defense might expand on defenses already available, I undertook to explore that topic.
The phrase "a cultural defense" suggests an either/or choice that any legal system might make. That matters are much more complex than this is part of the burden of this essay. A "cultural defense" in its most general sense refers to a wide range of ways in which evidence about a defendant's cultural …
Taking Action In New York On Climate Change, Michael B. Gerrard, David Driesen, Veronica Eady Famira, J. Kevin Healy, Katrina Kuh, Edward Lloyd, Eileen Millett, David Paget, Virginia Robbins, Patricia Salkin, James Sevinsky, James Van Nostrand
Taking Action In New York On Climate Change, Michael B. Gerrard, David Driesen, Veronica Eady Famira, J. Kevin Healy, Katrina Kuh, Edward Lloyd, Eileen Millett, David Paget, Virginia Robbins, Patricia Salkin, James Sevinsky, James Van Nostrand
Faculty Scholarship
The New York State Bar Association (NYSBA) Task Force on Global Warming (the Task Force) has been convened by NYSBA President Bernice Leber to summarize New York’s existing laws and programs regarding climate change and to make specific proposals that the State can implement in a timely and cost-effective fashion to reduce greenhouse gas (GHG) emissions and to prepare for the impacts of climate change. New York has taken many steps to address climate change; however, there is much more that can be done. The Task Force has not attempted to comprehensively suggest every possible action, but rather has selected …
Intra-Speaker Variability In Palatometric Measures Of Consonant Articulation, Christopher Dromey, Marybeth Sanders
Intra-Speaker Variability In Palatometric Measures Of Consonant Articulation, Christopher Dromey, Marybeth Sanders
Faculty Publications
Electropalatometry is a useful clinical and research tool for measuring linguapalatal contact. The goal of this study was to examine intra-speaker variability in performance. Twenty individuals spoke VCV nonsense words using a schwa in the initial position, the 15 palatal consonants, and three corner vowels, /ɑ/, /i/, /u/. A variability index was created to examine speaker consistency.
Different aspects of articulation (i.e. place, manner, voicing, coarticulation) were compared. Significant differences for variability were found for place of articulation in the /i/ vowel context and for manner of articulation in the /ɑ/ vowel context. Also for the /ɑ/ vowel, significant differences …
Gene Patents And The Product Of Nature Doctrine, John M. Conley
Gene Patents And The Product Of Nature Doctrine, John M. Conley
Faculty Publications
No abstract provided.
Judging Congress, Michael J. Gerhardt
Scary Patents, Stephen M. Mcjohn
Scary Patents, Stephen M. Mcjohn
Suffolk University Law School Faculty Works
The Federal Circuit, in In re Bilski, announced a new test for patentable subject matter, reversing a decades-long trend that had broadened patent subject matter to include business methods and software. To be patentable under Bilski, a process must (1) be tied to a particular machine or apparatus, or (2) transform a particular article into a different state or thing. The Supreme Court has granted cert. to review Bilski. Bilski gives little weight to the very statute it is interpreting or to the facts of the relevant Supreme Court cases. The court draws a test from selected language of those …
The Debt Financing Of Parenthood, Melissa B. Jacoby
The Debt Financing Of Parenthood, Melissa B. Jacoby
Faculty Publications
No abstract provided.
Bias In The Workplace: Consistent Evidence Of Sexual Orientation And Gender Identity Discrimination 1998-2008, M.V. Lee Badgett, Brad Sears, Holning S. Lau, Deborah Ho
Bias In The Workplace: Consistent Evidence Of Sexual Orientation And Gender Identity Discrimination 1998-2008, M.V. Lee Badgett, Brad Sears, Holning S. Lau, Deborah Ho
Faculty Publications
No abstract provided.
The Roberts Court And Access To Justice, Gene R. Nichol
The Roberts Court And Access To Justice, Gene R. Nichol
Faculty Publications
No abstract provided.
Vol. 12, No. 1: Full Issue, Water Law Review
Confronting Drought: Water Supply Planning And The Establishment Of A Strategic Groundwater Reserve, Ruth Langridge
Confronting Drought: Water Supply Planning And The Establishment Of A Strategic Groundwater Reserve, Ruth Langridge
Water Law Review
No abstract provided.
The Oklahoma Water Sale Moratorium: How Fear And Misunderstanding Led To An Unconstitutional Law, Mark A. Willingham
The Oklahoma Water Sale Moratorium: How Fear And Misunderstanding Led To An Unconstitutional Law, Mark A. Willingham
Water Law Review
No abstract provided.
Insufficiency Of New Hampshire's Instream Flow Regulation To Ensure The Viability Of Its Rivers As Economics Environmental, And Social Assets, Jason A. Weiner
Insufficiency Of New Hampshire's Instream Flow Regulation To Ensure The Viability Of Its Rivers As Economics Environmental, And Social Assets, Jason A. Weiner
Water Law Review
No abstract provided.