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Quantitative Prediction Of Body Surface Potentials From Myocardial Action Potentials Using A Summed Dipole Model, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

This paper demonstrates quantitatively, using streamlined mathematics, how the transmembrane ionic currents in individual cardiac muscle cells act to produce the body surface potentials of the electrocardiogram (ECG). From fundamental principles of electrostatics, anatomy, and physiology, one can characterize the strength of apparent dipoles along a wavefront of depolarization in a local volume of myocardium. Net transmembrane flow of ionic current in actively depolarizing or repolarizing tissue induces extracellular current flow, which sets up a field of electrical potential that resembles that of a dipole. The local dipole strength depends upon the tissue cross section, the tissue resistivity, the resting …

A Capacitively-Loaded Mems Slot Element For Wireless Temperature Sensing Of Up To 300c, S. Scott, D. Peroulis

Department of Electrical and Computer Engineering Faculty Publications

In this paper we present a new slot antenna with an embedded temperature sensor for remote sensing in harsh environment applications. When the antenna is illuminated with a plane wave it returns a signal. The returned signal's frequency is modulated by the loaded capacitance formed by an array of MEMS bimorph (metal-dielectric) cantilevers. The MEMS cantilevers deflect downwards when the temperature is changed from 20C to 300C. As a result, the resonant frequency of the slot is linearly tuned from 19.45 to 19.30 GHz. The design yields a totally passive and integrated antenna/sensor. The MEMS fabrication is inherently robust, does …

A Phenomenological Discrete Brittle Damage-Mechanics Model For Fatigue Of Mems Devices With Application To Liga Ni, T. S. Slack, F. Sadeghi, D. Peroulis

Department of Electrical and Computer Engineering Faculty Publications

Fatigue initiation and failure of various microelectromechanical systems (MEMS) is of significant importance as they gain widespread acceptance in sensors and electronics. This paper presents an approach for utilizing available experimental fatigue data to evaluate the fatigue lives of MEMS components. The approach is based on a phenomenological discrete material representation in which a domain is represented by a collection of rigid elements that interacts via springs along their boundaries. The principles of continuum damage mechanics are used to degrade the spring stiffnesses as brittle damage occurs when the domain is subjected to fatigue loading. The model utilizes experimental stress-life …

Syndromic Surveillance: Stl For Modeling, Visualizing, And Monitoring Disease Counts, Ryan P. Hafen, David E. Anderson, William S. Cleveland, Ross Maciejewski, David Ebert , Phd, Ahmad Abusalah, Mohamed Yakout, Mourad Ouzzani, Shaun J. Grannis

Department of Electrical and Computer Engineering Faculty Publications

Background

Public health surveillance is the monitoring of data to detect and quantify unusual health events. Monitoring pre-diagnostic data, such as emergency department (ED) patient chief complaints, enables rapid detection of disease outbreaks. There are many sources of variation in such data; statistical methods need to accurately model them as a basis for timely and accurate disease outbreak methods.

Methods

Our new methods for modeling daily chief complaint counts are based on a seasonal-trend decomposition procedure based on loess (STL) and were developed using data from the 76 EDs of the Indiana surveillance program from 2004 to 2008. Square root …

Application Of 3d Zernike Descriptors To Shape-Based Ligand Similarity Searching, Vishwesh Venkatraman, Padmasini Ramji Chakravarthy, Daisuke Kihara

Department of Biological Sciences Faculty Publications

Background

The identification of promising drug leads from a large database of compounds is an important step in the preliminary stages of drug design. Although shape is known to play a key role in the molecular recognition process, its application to virtual screening poses significant hurdles both in terms of the encoding scheme and speed.

Results

In this study, we have examined the efficacy of the alignment independent three-dimensional Zernike descriptor (3DZD) for fast shape based similarity searching. Performance of this approach was compared with several other methods including the statistical moments based ultrafast shape recognition scheme (USR) and SIMCOMP, …

A Subject Librarian’S Guide To Collaborating On E-Science Projects, Jeremy R. Garritano, Jake R. Carlson

Libraries Research Publications

For liaison or subject librarians, entering into the emerging area of providing researchers with data services or partnering with them on cyberinfrastructure projects can be a daunting task. This article will provide some advice as to what to expect and how providing data services can be folded into other liaison duties. New skills for librarians and traditional skills that can be adapted to data curation work will also be discussed. A case study on the authors' experiences collaborating with two chemistry faculty on an e-science project serves as the framework for the majority of this article.

Institutional Repositories And Research Data Curation In A Distributed Environment, Michael Witt

Libraries Research Publications

Broadly speaking, the lack of a framework for organizing, preserving, and making research data available for the long-term has resulted in valuable datasets becoming lost or discarded. The approach of the Distributed Data Curation Center of the Purdue University Libraries has been to integrate librarians and the principles of library and archival sciences with domain sciences, computer and information sciences, and information technology to address the challenges of managing collections of research data and to learn how to better support interdisciplinary research through data curation. One piece of infrastructure that supports these activities is a “distributed institutional repository” that includes …

Developing Core Leadership Competencies For The Library Profession, Shorlette Ammons-Stephens, Holly J. Cole, Keisha Jenkins-Gibbs, Catherine Fraser Riehle, William H. Weare Jr.

Libraries Faculty and Staff Scholarship and Research

No abstract provided.

Sibling Death And Death Fear In Relation To Depressive Symptomatology In Older Adults, Victor G. Cicirelli

Department of Psychological Sciences Faculty Publications

Previously overlooked factors in elders’ depressive symptomatology were examined, including death fear, sibling death, and sibling closeness. Participants were 150 elders (61 men, 89 women) aged 65 to 97 with at least one sibling. Measures were: proportion of deceased siblings, sibling closeness, the Death Fear subscale of the DAP-Revised, and the CES-D depression scale (20-item adult form). Age and education were exogenous variables in a structural equation model. Death fear, sibling closeness, and proportion of dead siblings were directly related to depression, with path coefficients of .42, -.24, and .13, respectively. Proportion of dead siblings had indirect effects on depression, …

Non-Marital Romantic Relationship Commitment And Leave Behavior: The Mediating Role Of Dissolution Consideration, Laura E Vanderdrift, Christopher Agnew, Juan E. Wilson

Department of Psychological Sciences Faculty Publications

Two studies investigated the process by which individuals in non-marital romantic relationships characterized by low commitment move toward enacting leave behaviors. Predictions based on the behavioral, goal, and implementation intention literatures were tested using a measure of dissolution consideration developed for this research. Dissolution consideration assesses how salient relationship termination is for an individual while one’s relationship is intact. Study 1 developed and validated a measure of dissolution consideration and Study 2 was a longitudinal test of the utility of dissolution consideration in predicting the enactment of leave behaviors. Results indicated that dissolution consideration mediates the association between commitment and …

Extensive Training Is Insufficient To Produce The Work-Ethic Effect In Pigeons, Marco Vasconcelos, Peter J. Urcuioli

Department of Psychological Sciences Faculty Publications

Zentall and Singer (2007a) hypothesized that our failure to replicate the work-ethic effect in pigeons (Vasconcelos, Urcuioli, & Lionello-DeNolf, 2007) was due to insufficient overtraining following acquisition of the high- and low-effort discriminations. We tested this hypothesis using the original work-ethic procedure (Experiment 1) and one similar to that used with starlings (Experiment 2) by providing at least 60 overtraining sessions. Despite this extensive overtraining, neither experiment revealed a significant preference for stimuli obtained after high effort. Together with other findings, these data support our contention that pigeons do not reliably show a work-ethic effect.

2009 Rosabeth Moss Kanter Award For Excellence In Work-Family Research Publication, Center For Families, Center For Work And Families

Center for Families Publications

No abstract provided.

Class Action Arbitration, William H. Baker

Cardozo Journal of Conflict Resolution

Class action arbitrations are a relatively recent phenomenon in the United States, but the number of such arbitrations is expanding at a rapid rate. As of August 2008, the American Arbitration Association ("AAA") has administered 246 class action arbitrations and Judicial Arbitration and Mediation Services, Inc. ("JAMS"), another major U.S. arbitral institution, has also administered a substantial number of class arbitrations.

Challenging Class Action Bans In Mandatory Arbitration Clauses, F. Paul Bland Jr., Claire Prestel

Cardozo Journal of Conflict Resolution

After a brief summary of relevant Supreme Court doctrine, this article sets out the argument that exculpatory class action bans violate many states' generally applicable contract law and responds to several common corporate defenses offered in support of such bans.

Bad Medicine: On Disciplining Physician Felons, Milton Heumann, Brian Pinaire, Simon Burger

Cardozo Journal of Conflict Resolution

Perhaps it is the white coat or the degrees encased and mounted on the wall. Perhaps it is the Hippocratic Oath that new physicians recite and that established physicians have putatively internalized over time, or perhaps it is the title, "Doctor," which conjures up images of a stethoscope, a black bag, house calls, nurture, and trust. When we are sick, we head to the doctor. Young children are urged to become doctors. When we watch television or go to the movies doctors are, with certain recent exceptions, portrayed in a positive light as compared to lawyers or politicians. In this …

Yada, Yada, Yada: Seinfeld, The Law And Mediation, Paul Devendorf

Cardozo Journal of Conflict Resolution

This Note will first explore the popularity of Seinfeld and discuss the influence of Seinfeld on legal culture. Part III details cultivation theory and explores the possible influences Seinfeld may have in shaping its viewers' impressions of formal law. Specific instances in-which Seinfeld has ridiculed formal legal practices and offered social criticisms of the legal profession are analyzed in Part IV. Part V describes a specific episode of Seinfeld and illustrates the consequences of parties' refusal to reach mutually satisfactory resolutions, the need for mediation to resolve highly contentious disputes, and the inadequacy of the legal system to provide an …

Application Of Cascade Theory To Online Systems: A Study Of Email And Google Cascades, April Mara Barton

Minnesota Journal of Law, Science & Technology

No abstract provided.

Biology And Impacts Of Pacific Island Invasive Species. 5. Eleutherodactylus Coqui, The Coqui Frog (Anura: Leptodactylidae), Karen H. Beard, William C. Pitt, Emily A. Price

United States Department of Agriculture Wildlife Services: Staff Publications

The nocturnal, terrestrial frog Eleutherodactylus coqui, known as the Coqui, is endemic to Puerto Rico and was accidentally introduced to Hawai‘i via nursery plants in the late 1980s. Over the past two decades E. coqui has spread to the four main Hawaiian Islands, and a major campaign was launched to eliminate and control it. One of the primary reasons this frog has received attention is its loud mating call (85–90 dB at 0.5 m). Many homeowners do not want the frogs on their property, and their presence has influenced housing prices. In addition, E. coqui has indirectly impacted the …

Serologic Evidence Of Avian Influenza (H4n6) Exposure In A Wild-Caught Raccoon, Nathan M. Roberts, David J. Henzler, Larry Clark

United States Department of Agriculture Wildlife Services: Staff Publications

Growing concerns about avian influenza, and its effect on agriculture and human health, have highlighted the need to understand the role of wildlife in maintaining and spreading the virus. We surveyed the wildlife inhabiting a poultry farm with recent I-I3N6 and H4N6 avian influenza virus exposure in Pennsylvania, U.S.A. One raccoon (Procyon lotor) tested positive for H4N6 antibodies. This is the first recorded incident of avian influenza exposure in a wild raccoon. We suggest that raccoons may play a role in the transmission of avian influenza viruses and in compromising biosecurity efforts at poultry operations.

An Overview Of Historical Beaver Management In Arizona, Christopher Carrillo, David Bergman, Jimmy D. Taylor Ii, Dale L. Nolte, Patrick Viehoever, Mike Disney

United States Department of Agriculture Wildlife Services: Staff Publications

In the mid-1820s, Anglo-American fur trappers, known as "mountain men," entered Arizona and began trapping beaver (Castor canadensis). In Arizona there have been a number of famous mountain men such as Sylvester and James Pattie, Ewing Young, Jededia Smith, and Bill Williams who trapped along the waterways in northern and southern Arizona. Although the heyday of mountain men lasted only a few decades due to a population decline of beaver, management of these animals continues to this day. The purpose of managing beavers shifted from monetary gain to controlling wildlife damage. During the late 1900s, beaver were still …

Surveillance For Highly Pathogenic Avian Influenza In Wild Birds In The Usa, Thomas J. Deliberto, Seth R. Swafford, Dale L. Nolte, Kerri Pedersen, Mark W. Lutman, Brandon S.. Schmit, John A. Baroch, Dennis J. Kohler, Alan B. Franklin

United States Department of Agriculture Wildlife Services: Staff Publications

As part of the USA’s National Strategy for Pandemic Influenza, an Interagency Strategic Plan for the Early Detection of Highly Pathogenic H5N1 Avian Influenza in Wild Migratory Birds was developed and implemented. From 1 April 2006 through 31 March 2009, 261 946 samples from wild birds and 101 457 wild bird fecal samples were collected in the USA; no highly pathogenic avian influenza was detected. The United States Department of Agriculture, and state and tribal cooperators accounted for 213 115 (81%) of the wild bird samples collected; 31, 27, 21 and 21% of the samples were collected from the Atlantic, …

Rangelands Use And Management At The Border Area Of Northeast Mexico And South Texas/ Uso Y Manejo De Los Pastizales En La Franja Fronteriza Del Noreste De México Y Sur De Texas, Eduardo A. Gonzalez-V, David G. Hewitt, J. Alfonso Ortega-Santos, Randy W. Deyoung, Tyler A. Campbell, Fred C. Bryant

United States Department of Agriculture Wildlife Services: Staff Publications

Land use in southern Texas and northern Mexico is changing away from traditional livestock production and toward wildlife based recreation as white tailed deer (Odocoileus virginianus) hunting. The objective was to conduct a landowner survey to document land use patterns along the Rio Grande River in Texas and Mexico. A survey was developed and written in both English and Spanish, and administered to the landowners or managers along the Rio Grande River in Texas and Mexico, during February to June of 2008. In Texas the survey was administered in counties that border the Rio Grande River between Starr …

Landscape Genetics Of Raccoons (Procyon Lotor) Associated With Ridges And Valleys Of Pennsylvania: Implications For Oral Rabies Vaccination Programs, J. Jeffrey Root, Robert B. Puskas, Justin W. Fischer, Craig B. Swope, Melissa A. Neubaum, Serena A. Reeder, Antoinette J. Piaggio

United States Department of Agriculture Wildlife Services: Staff Publications

Raccoons are the reservoir for the raccoon rabies virus variant in the United States. To combat this threat, oral rabies vaccination (ORV) programs are conducted in many eastern states. To aid in these efforts, the genetic structure of raccoons (Procyon lotor) was assessed in southwestern Pennsylvania to determine if select geographic features (i.e., ridges and valleys) serve as corridors or hindrances to raccoon gene flow (e.g., movement) and, therefore, rabies virus trafficking in this physiographic region. Raccoon DNA samples (n = 185) were collected from one ridge site and two adjacent valleys in southwestern Pennsylvania (Westmoreland, Cambria, Fayette, …

Evaluation Of An Epitope-Blocking Enzyme-Linked Immunosorbent Assay For The Detection Of Antibodies To Influenza A Virus In Domestic And Wild Avian And Mammalian Species, Heather J. Sullivan, Bradley J. Blitvich, Kaci K. Vandalen, Kevin T. Bentler, Alan B. Franklin, J. Jeffrey Root

United States Department of Agriculture Wildlife Services: Staff Publications

An epitope-blocking enzyme-linked immunosorbent assay (bELISA) was developed for the detection of antibodies to influenza A virus in taxonomically diverse domestic and wild vertebrate species. In contrast to the bELISAs published previously that require reagent production, manipulation by the end-user, or have not been evaluated for use with both mammalian and avian species, this assay is performed using commercially available recombinant nucleoprotein antigen and corresponding nucleoprotein-specific monoclonal antibody and has been shown to work with multiple avian and mammalian species. The efficacy of the bELISA as a serum screening assay was compared to the agar gel immunodiffusion (AGID) assay using …

Humoral Immunity To West Nile Virus Is Long-Lasting And Protective In The House Sparrow (Passer Domesticus), Nicole M. Nemeth, Paul T. Oesterle, Richard A. Bowen

United States Department of Agriculture Wildlife Services: Staff Publications

The house sparrow (Passer domesticus) is a common and abundant amplifying host of West Nile virus (WNV) and many survive infection and develop humoral immunity. We experimentally inoculated house sparrows with WNV and monitored duration and protection of resulting antibodies. Neutralizing antibody titers remained relatively constant for ≥ 36 months (N = 42) and provided sterilizing immunity for up to 36 months post-inoculation in 98.6% of individuals (N = 72). These results imply that immune house sparrows are protected from WNV infection for multiple transmission seasons. Additionally, individuals experiencing WNV-associated mortality reached significantly higher peak viremia …

West Nile Virus Detection In Nonvascular Feathers From Avian Carcasses, Nicole M. Nemeth, Ginger R. Young, Kristen L. Burkhalter, Aaron C. Brault, William K. Reisen, Nicholas Komar

United States Department of Agriculture Wildlife Services: Staff Publications

West Nile virus (WNV) is a public health threat and has caused the death of thousands of North American birds. As such, surveillance for WNV has been ongoing, utilizing numerous biological specimens and testing methods. Nonvascular (i.e., fully grown) feathers would provide a simple method of collection from either dead or live birds of all ages and molt cycles, with presumably less biosafety risk compared with other specimen types, including feather pulp. The current study evaluates WNV detection in nonvascular feathers removed from naturally infected avian carcasses of several species groups. Feathers of corvid passeriforms had the highest sensitivity of …

Energy Absorption Characteristics Of Mwcnt, Swasti Gupta

Electronic Theses and Dissertations

No abstract provided.

Expanding The Crime Of Genocide To Include Ethnic Cleansing: A Return To Established Principles In Light Of Contemporary Interpretations, Micol Sirkin

Seattle University Law Review

It may be surprising to discover that ethnic cleansing is legally distinct from genocide considering that the media use these terms interchangeably. Currently, no formal legal definition of ethnic cleansing exists. This Comment specifies how ethnic cleansing fits into the definition of genocide’s distinctly destructive purpose and effect. I argue that because ethnic cleansing and genocide result in similar harms and derive from similar agendas, international courts ought to find perpetrators guilty of the crime of genocide when genocidal acts are committed with the intent to create an ethnically homogenous territory. A policy of ethnic cleansing is a genocidal policy. …

Medical Malpractice And The Political Environment : Explaining Variation In Medical Malpractice Awards Among The States, Christopher Nicklaus Bailey

Electronic Theses and Dissertations

No abstract provided.

Assessment Of The Tissue Distribution Of A Novel Binding Site For Angiotensins Ii And Iii In The Mouse, Felicia Rabey

Electronic Theses and Dissertations

No abstract provided.