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Synthesis And Evaluation Of Phosphopeptides Containing Iminodiacetate Groups As Binding Ligands Of The Src Sh2 Domain, Guofeng Ye, Aaron D. Schuler, Yousef Ahmadibeni, Joel R. Morgan, Absar Faruqui, Kezhen Huang, Gongqin Sun, John A. Zebala, Keykavous Parang

Pharmacy Faculty Articles and Research

Phosphopeptide pTyr-Glu-Glu-Ile (pYEEI) has been introduced as an optimal Src SH2 domain ligand. Peptides, Ac-K(IDA)pYEEIEK(IDA) (1), Ac-KpYEEIEK (2), Ac-K(IDA)pYEEIEK (3), and Ac-KpYEEIEK(IDA) (4), containing 0–2 iminodiacetate (IDA) groups at the N- and C-terminal lysine residues were synthesized and evaluated as the Src SH2 domain binding ligands. Fluorescence polarization assays showed that peptide 1 had a higher binding affinity (Kd = 0.6 μM) to the Src SH2 domain when compared with Ac-pYEEI (Kd = 1.7 μM), an optimal Src SH2 domain ligand, and peptides 2–4 (Kd = 2.9–52.7 μM). The binding affinity of peptide 1 to the SH2 domain was reduced …

An Investigation Of The Factors Related To Direct Care Staffs' Knowledge Of Effectiveness Instructional Strategies For People With Developmental Disabilities, Craig Cook

Electronic Theses and Dissertations

The Medicaid Home and Community Based Services Waiver (HCBS) funds services for people with developmental disabilities in community based group homes. The purpose of the Medicaid HCBS Waiver is to: (1) support alternatives to institutions, (2) promote independence, (3) maximize functioning, and (4) support community integration. Direct care staff members have primary, day to day contact with people with developmental disabilities living in group home settings. Residential agencies for people with developmental disabilities have the responsibility to train direct care staff in the use of effective teaching strategies in order to realize the purpose of the Medicaid HCBS waiver. Direct …

Child Sexual Abuse, Ptsd, And Substance Use: Predictors Of Revictimization In Adult Sexual Assault Survivors, Sarah E. Ullman, Cynthia J. Najdowski, Henrietta Filipas

Psychology Faculty Scholarship

This study examined the unique effects of child sexual abuse simultaneously with post-traumatic stress disorder symptom clusters, problem drinking, and illicit drug use in relation to sexual revictimization in a community sample of female adult sexual assault victims. Participants (N = 555) completed two surveys a year apart. Child sexual abuse predicted more post-traumatic stress disorder symptoms in adult sexual assault victims. Posttraumatic stress disorder numbing symptoms directly predicted revictimization, whereas other post-traumatic stress disorder symptoms (reexperiencing, avoidance, and arousal) were related to problem drinking, which in turn predicted revictimization. Thus, numbing symptoms and problem drinking may be independent risk …

Prospective Effects Of Sexual Victimization On Ptsd And Problem Drinking, Cynthia J. Najdowski, Sarah E. Ullman

Psychology Faculty Scholarship

Posttraumatic stress disorder (PTSD) and problem drinking are common and often co-occurring sequelae experienced by women survivors of adult sexual assault, yet it remains unclear whether survivors drink to cope with PTSD symptoms or whether PTSD symptoms are exacerbated by drinking. Thus, we used a cross-lagged panel design with a large (N = 555), ethnically diverse sample of women assault survivors to determine whether PTSD prospectively led to problem drinking or vice versa. We also examined whether cumulative sexual victimization experiences related to greater PTSD and problem drinking. Structural equation modeling revealed that child sexual abuse was associated with …

Revictimization As A Moderator Of Psychosocial Risk Factors For Problem Drinking In Female Sexual Assault Survivors, Cynthia J. Najdowski, Sarah E. Ullman

Psychology Faculty Scholarship

Adult sexual assault (ASA) survivors report greater levels of problem drinking than do other women, and research suggests that their coping strategies, reactions from their social networks, and traumatic life events affect their problem drinking. The links between these factors and problem drinking may be moderated by whether survivors are revictimized, yet research has not examined this possibility. Therefore, the current study examined psychosocial factors, problem drinking, and revictimization in women ASA survivors. Method: Community-dwelling urban women (n = 555) who had experienced an ASA completed a mail survey at Time 1 (T1) and were resurveyed 1 year later …

Understanding Adults’ Perceptions Of Juvenile Offenders, Margaret C. Stevenson, Cynthia J. Najdowski, Bette L. Bottoms, Tamara M. Haegerich

Psychology Faculty Scholarship

In adult criminal court, cases involving juveniles can be decided by jurors rather than by family or juvenile court judges. It is, therefore, important to understand adults' perceptions of juvenile defendants and the factors that influence jurors' decisions in criminal cases involving juveniles. This research has value for research psychologists interested in legal decision making and for professionals within the legal system who seek to understand how jurors react to juveniles accused of crimes and how they reach their verdicts in cases involving juveniles. In this chapter, we consider three broad categories of factors that affect perceptions of juveniles: (1) …

The Law, Culture, And Economics Of Fashion, C. Scott Hemphill, Jeannie Suk

Center for Contract and Economic Organization

Fashion is one of the world’s most important creative industries. It is the major output of a global business with annual U.S. sales of more than $200 billion — larger than those of books, movies, and music combined. Everyone wears clothing and inevitably participates in fashion to some degree. Fashion is also a subject of periodically rediscovered fascination in virtually all the social sciences and the humanities. It has provided economic thought with a canonical example in theorizing about consumption and conformity. Social thinkers have long treated fashion as a window upon social class and social change. Cultural theorists have …

The Bulletin, Undergraduate Catalog 2009-2011 (2009), Minnesota State University Moorhead

Undergraduate Bulletins (Catalogs)

No abstract provided.

Climate Change And The Right To Food: A Comprehensive Study, Human Rights Institute

Human Rights Institute

Climate change and the policies instituted to combat it are affecting the realiza- tion of the right to food in myriad, often unnoticed ways. This report highlights how – despite the common objective to preserve human welfare for present and future generations – the climate change regime and the human rights regime addressing the right to food have failed to coordinate their agendas and to collab- orate to each other’s mutual benefit. The current climate change regime fails to accurately address the human harms resulting from climate change itself, and is not operating with the necessary safeguards and preventive measures …

Cultural Culprits, Michelle Mckinley

Studio for Law and Culture

This paper draws from a longer Article that examines questions of agency, victimization, and cultural essentialism in U.S. asylum adjudication and cultural defense cases specifically, and in international human rights law more broadly. I explore the adjudication of FGC asylum claims based on cultural persecution” that encode a racialized view of culture. I describe the historical trajectory of contemporary FGC claims through a detailed analysis of colonial anti-excision campaigns. I compare early 19th century anti-excision campaigns with contemporary maternal imperialism, as international law, UN agencies, and international financial institutions became more responsive to feminist concerns about eradicating FGC. Throughout the …

Blackboard Jungle: Delinquency, Psychiatry, And The Bio-Politics Of Brown, Anders Walker

Studio for Law and Culture

In 1955, Metro-Goldwyn-Mayer released a controversial film about juvenile delinquency entitled Blackboard Jungle. Georgia Governor Ernest Vandiver subsequently used the film as a metaphor for what would happen to southern schools were Brown enforced, marking the beginnings of a much larger campaign to articulate southern resistance to integration in popular terms. Taking Blackboard Jungle as a starting point, this article recovers the intersection between discourses of delinquency and desegregation at mid-century, showing how civil rights groups and segregationists alike both drew from mass culture and social psychiatry to advance their constitutional agendas. It concludes by showing that even as …

St. Dominic Deaf Center, January-February 2009

Saint Dominic Deaf Center

A newsletter published for Deaf Catholics in Houston, TX

Saint Dominic Deaf Center Finding Aid

Sustainable Development And Exhaustible Resources: The Case Of Bauxite Mining In Vietnam, Hoa Hoang

Masters Culminating Experiences (1993-2011)

In 2007, the Vietnamese government declared an ambitious master plan to extract its bauxite resources, mainly concentrated in the Central Highlands. The impact of bauxite mining on the livelihoods of indigenous people and the macroeconomy have been debated by many scientists, economists, environmentalists, and journalists, both in Vietnam and among the Vietnamese who live overseas. From a holistic perspective to sustainable development, this paper analyzes the potential impacts of the Tan Rai and Nhan Co bauxite mining and alumina refining projects, the major part of the Vietnamese government’s master plan. At a macroeconomic level, the possible occurrence of the “resource …

Modeling Cockpit Interface Usage During Lunar Landing Redesignation, Zarrin K. Chua, Laura M. Major, Karen M. Feigh

International Symposium on Aviation Psychology - 2009

Fulfilling NASA’s space exploration objectives requires precision landing to reach lunar sites of interest. During the approach and landing stages, a landing point redesignation (LPR) display will provide information to the crew regarding the characteristics of alternate touchdown points. Building on a previous study which examined crew tasks during LPR but did not account for the specialized behavior of experts, this investigation will present a new task sequence model, specific to expert decision-making. This analysis furthers the development of a predictive task execution model, which is used to test the efficacy of alternate information display and operator actuator design concepts. …

Post-Traumatic Stress In Flight Attendant's Labor, Filipieva Tatiana Phd

International Symposium on Aviation Psychology - 2009

Airline crashes, hijackings, turbulence incidents and other emergencies have the potential for inflicting severe emotional trauma in flight attendants involved either directly or indirectly. A critical incident is a part of the extreme professions in aviation. Although the aviation industry attempted to bring help following an air disaster, post-traumatic stress is still one of the most misdiagnosed and ignored illnesses that can beset an individual. In the article, which is based on the results of Russian and American aviation psychologists’ research, we try to answer the questions: How post-traumatic stress affects cabin crew’s work performance and flight attendants’ life? How …

Adaptation Of Crm Training For The Railway Industry Operational Safety Benefits, Matthew T.S. Tsang, Hans-Juergen Hoermann

International Symposium on Aviation Psychology - 2009

In aviation, Crew Resource Management (CRM) was developed to address safety issues derived from accident and incident investigations. As CRM has proven its effectiveness by improving teamwork, communication and staff responses to operational hazards, there have been many attempts to expand this concept into other high-risk sectors such as medical, nuclear, or military. Although some work was also conducted to modify CRM for the railway industry, no such experiences yet existed in China or Hong Kong. Having observed the effectiveness of CRM and Line Oriented Training (LOT) in aviation, this paper documents the introduction and initial evaluation of CRM and …

Training To Reduce Aviation Maintenance Error: Assessing Maintenance Resource Management Programs In Commercial Aviation, Erin E. Block, Edward J. Sabin, Manoj S. Patankar

International Symposium on Aviation Psychology - 2009

Maintenance resource management (MRM) training is intended to integrate existing technical skills of maintenance employees with interpersonal skills/human factors knowledge to improve communication effectiveness & maintenance safety. The FAA suggests successful MRM training not only teaches error avoidance, but also the adoption of attitudes that support a safety culture. This coincides with FAA encouragement to incorporate systems theory into MRM training to put human factors issues in larger organizational context. Many programs currently use the MRM/TOQ survey to assess the impact of MRM training & its effectiveness in changing safety-related attitudes.

The Effects Of Success Related Pressure On Information Processing Strategies And Plan Continuation Error, Bourgeon Léonore, Valot Claude, Fauconnet Sophie, Loyau Fanny, Navarro Claude

International Symposium on Aviation Psychology - 2009

An experiment was conducted to explore whether plan continuation errors could be explained by two types of perseveration behaviours: Perseveration in a wrong Representation do the Situation (PRS) and Perseveration in a risky Plan of Action (PPA). Effects of success-related pressure and flight phase on pilots performance were also examined. Six scenarios were created where expected or unexpected threats had to be managed. Pilots chose between three plans of actions corresponding to PPA, PRS and Flexibility. Results showed that the two types of perseveration could effectively explain plan continuation errors even though PPA characterised cruise phase and PRS was more …

How Differences In Spatial Ability Influence Inexperienced Users In A Visual Perceptual Aviation Task, Michael T. Curtis, Florian G. Jentsch, Crystal Maraj

International Symposium on Aviation Psychology - 2009

The approach and landing phase of flight is widely recognized as one of the most difficult phases of flight. More specifically, professionals in aviation training report difficulty in training inexperienced pilots on execution of visual approaches. The current paper focuses on our efforts to develop a perceptual skill trainer using a static image discrimination task. From a perceptual standpoint there are a number of documented visual environmental cues that have been found to impact one’s ability to judge distances. These distracting cues can cause individuals to misjudge distance to landing surfaces, and subsequently result in an unstable or unsafe approach. …

Assessing Novel Adaptive Displays Impact On Pilot Performance, Sean L. Guarino, Karen Harper, Emilie Roth, Dahai Liu, Mark Bartosiewicz, Dennis Vincenzi

International Symposium on Aviation Psychology - 2009

Combat aircraft advances have led to a dramatic increase in the operational tempo facing the Navy pilot, increasing the likelihood for Situation Awareness (SA) failures, biased decision-making and information overload. We designed a system for constructing intelligent adaptive displays to address these issues and, within it, designed and evaluated two interfaces targeted at tactical SA challenges: (1) a Weapons Employment Zone (WEZ) Display designed to support awareness of combat geometry; and (2) an Adaptive Boundary Display (ABD) designed to warn pilots of impending border infractions that would compromise Rules of Engagement (ROEs). We tested the ability of these displays to …

Comparing The Accuracy Of Performing Digital And Paper Checklists Using A Feedback Intervention Package During Normal Workload Conditions In Simulated Flight, William G. Rantz Ph.D., Bryan W. Hilton B.S.

International Symposium on Aviation Psychology - 2009

This study examined whether pilots completed airplane digital and paper checklists more accurately when they received post-flight graphic and verbal feedback. Participants were 6 college student pilots with instrument ratings. The task consisted of flying flight patterns using a Frasca 241 Flight Training Device which emulates the Cirrus SR20. An alternating treatment, multiple baseline design across pairs with reversal was used. Visual inspection and statistical analysis of the data suggests that paper checklist accuracy does not differ significantly from digital checklist accuracy during normal workload conditions. The results also suggest that graphic feedback and praise can be used to increase …

Results From The First Faa Industry Training Standards (Fits) Commercial Pilot Training Course – A Student’S Perspective, Paul A. Craig, Wendy S. Beckman, Mark Callender, Steve Gossett, Wayne Dornan

International Symposium on Aviation Psychology - 2009

In January 2008, students in the Professional Pilot program at Middle Tennessee State University (MTSU) began training using an FAA Industry Training Standards (FITS) Commercial Pilot curriculum. The course was accepted as a scenario-based and competency-based curriculum by the FAA as a “Special Curricula.” Students entered the FITS Commercial Pilot course having completed their Private Pilot Certificate and Instrument Rating. Some of the students had completed a FITS accepted and FAA approved combined Private/Instrument course, while others had completed separate Private Pilot and Instrument courses. The first thirty-three students completed the course with lower total flight times than students have …

Control-Force Inputs Obtained From Pilots And Nonpilots (Flight Attendants): Comparison With Established Handbook Distributions Of Performance, Dennis B. Beringer

International Symposium on Aviation Psychology - 2009

Earlier reports in this series (Beringer, 2006-2008) have reported the force that pilots and nonpilots could exert on flight controls. This paper presents a comparison of some well-known tables of human strength with the values from recent samples of women and men pilots and nonpilots in an attempt to determine how closely those distributions fit tabled distributions of human strength. Findings suggest that some other samples may be used to approximate the difficult-to-sample Part 121 female pilots if the data are treated properly. Specifically, yoke-activation tasks for the female pilots could be reasonably well approximated by fractional performance values of …

Knowledge And Skill-Based Evaluation Of Simulated And Live Training – From Evaluation Framework To Field Application, Martin Castor, Jonathan Borgvall, Winston Bennett Jr.

International Symposium on Aviation Psychology - 2009

In a study, a simulated spin-up exercise and the corresponding large-scale live military flight training exercise was evaluated based on the Alliger et al. augmented taxonomy of Kirkpatrick’s training criteria. The data collection was developed and designed to assess the training from reactions to in-simulator knowledge and skill development to operative training effect. The basis for the evaluation was knowledge and skills identified with the Mission Essential Competencies (MEC) process. Using surveys, quantitative and qualitative data from 14 fighter pilots were collected regarding reactions to training, perceived training value and additional training needs. This paper will present the rationale and …

Effects Of Visual, Seat, And Platform Motion During Flight Simulator Air Transport Pilot Training And Evaluation, Judith Bürki-Cohen, Andrea L. Sparko, Young Jin Jo, Tiauq H. Go

International Symposium on Aviation Psychology - 2009

Access to affordable and effective flight-simulation training devices (FSTDs) is critical to safely train airline crews in aviating, navigating, communicating, making decisions, and managing flightdeck and crew resources. This paper provides an overview of the Federal Aviation Administration- Volpe Center Flight Simulator Human Factors Program examining the requirements for the qualification and use of FSTDs. We will summarize past research investigating the need for a full hexapod-platform motion system, describe regulatory and industry developments, and report on current activities.

Proposing Attitude Indicator Modifications To Aid In Unusual Attitude Recovery, Nathan B. Maertens

International Symposium on Aviation Psychology - 2009

Pilots’ inability to recover from unusual attitudes (UA) is a major factor in loss of control in-flight (LOCIF) accidents, the largest cause of commercial aviation fatalities (Boeing, 2008). One study found 58% of professional pilots and 72% of general aviation pilots were unable to recover from LOCIF upsets (Regional Aviation News, 2008). Statistics also show that LOCIF is the only fatal aviation accident type not to appreciably decrease over a 21 year period ending in 2002 (Sumwalt, 2003a). A revision of the attitude indicator (AI) is proposed to examine if this would reduce the problem by keeping pilots from flying …

Development Of Method For Crm Skills Asessment, Hiroka Tsuda, Tomoko Iijima, Fumio Noda, Kohei Funabiki

International Symposium on Aviation Psychology - 2009

Crew Resource Management (CRM) is currently considered as one of the most effective methods for avoiding human errors or minimizing their effects. In training, measurement of the level of flight crews’ CRM Skills is necessary in order to evaluate objectively which Skills have been adequately learned and which are lacking. The Japan Aerospace Exploration Agency (JAXA) has developed CRM Skills Behavioral Markers and CRM Skills Measurement Methods that can identify a crew’s level of CRM Skills by which human errors and threats are managed. A series of simulated-LOFT (line oriented flight simulation training) were conducted to examine the applicability of …

Air Traffic Control Crew Resource Management: To Find Truth And Facilitate Change, Skip Grieser M.Ed.

International Symposium on Aviation Psychology - 2009

The Federal Aviation Administration’s Air Traffic Organization Office of Safety sponsors a comprehensive and ongoing program of Crew Resource Management (CRM), Human Factors in Air Traffic Control (ATC). CRM begins with a oneday workshop for all field ATC personnel, including management, staff, supervisors, and air traffic controllers. Facilitators present principles and methods in teamwork, individual performance, and Threat and Error Management, and participants discuss and record how they can use those principles and methods in their air traffic operations and safety cultures. Participants identify local safety issues and record their own recommendations, which then are compiled from all the workshops …

Coginitve Task Analysis Of Distributed Network-Centric Information For The Promotion Of Shared Situational Awareness Within Collaborative Uas Operations, Jeffery A. Getzlaff, Allen J. Rowe

International Symposium on Aviation Psychology - 2009

A hybrid model of cognitive task analysis coupled with activity theory and team cognition was evaluated to determine human-computer interface (HCI) design factors that promote Shared Situational Awareness (SSA) within a collaborative unmanned aerial system (UAS). A computer testbed simulation was created for use with participants in a time-sensitive Intelligence, Surveillance, and Reconnaissance (ISR) and weapons engagement mission testing scenario. A cognitive analysis was performed which consisted of a Hierarchical Task Analysis (HTA), Applied Cognitive Task Analysis (ACTA), time-sensitive activity analysis, and coordinated team cognition. Results from testing indicated that the promotion of situational awareness (SA) was enabled by network-centric …

Simulator Sickness In The Flight School Xxi Th-67 Flight Motion Simulators, Catherine Webb M.S., Julie Bass Ssg, David Johnson Ph.D., Amanda Kelley Ph.D., Christopher Martin M.D., Robert Wildzunas Ph.D.

International Symposium on Aviation Psychology - 2009

Simulator sickness (SS) is a common problem during flight training and can affect both instructor pilots (IPs) and student pilots (SPs). This study was conducted in response to complaints about a new rotary wing flight simulator. To investigate, Simulator Sickness Questionnaire (SSQ) data were collected from 129 SPs and 73 IPs. Analysis of these data helped direct recommendations based on the scientific literature for reducing SS. One year later, a post-test collected SSQ data from 50 SPs and 25 IPs. To test the effectiveness of the recommendations, a 2 (experience) x 2 (time) between-subjects Multivariate Analysis of Variance was used. …