Digital Commons Network^™

Hierarchical Summer Habitat Selection By The North American Porcupine In Western Montana, Katie Ann Mally

Graduate Student Theses, Dissertations, & Professional Papers

The North American porcupine (Erethizon dorsatum) has continually been a species of low priority for research and conservation efforts in the western United States. While many porcupine populations have been studied in North America, little to no research has been done on porcupines in western Montana or habitats of similar composition. More recently it has been noted that porcupine sightings have become rare in western Montana is areas where sightings were once common. Due to the overall lack of information about western porcupine populations it is imperative to gather basic natural history information in order to make informed management decisions. …

Studies Of The Dimerization And Packaging Signals In Hiv-2 Rna, Tayyba Tabassum Baig

Graduate Student Theses, Dissertations, & Professional Papers

The investigation of sequences and structures in the 5' untranslated leader region (5'UTR) of HIV genomic RNA is essential for understanding viral replication because the 5'UTR regulates several essential functions by the alternate presentation and sequestration of signals through conformational changes. Our main focus in this study was to understand those sequences and structures that are involved in dimerization and packaging of HIV-2 RNA. Progressing from previous findings, we studied in detail a 10-nucleotide palindrome sequence (pal; 5'-GGAGUGCUCC-3') of the 5'UTR, located within the major packaging signal, upstream of the dimerization signal (SL1: stem loop-1). Pal has been shown to …

Kinetics And Thermodynamics Of Salt-Dependent T7 Gene 2.5 Protein Binding To Single- And Double-Stranded Dna., Leila Shokri, Boriana Marintcheva, Mootaz Eldib, Andreas Hanke, Ioulia Rouzina, Mark C. Williams

Physics & Astronomy Faculty Publications

Bacteriophage T7 gene 2.5 protein (gp2.5) is a single-stranded DNA (ssDNA)-binding protein that has essential roles in DNA replication, recombination and repair. However, it differs from other ssDNA-binding proteins by its weaker binding to ssDNA and lack of cooperative ssDNA binding. By studying the rate-dependent DNA melting force in the presence of gp2.5 and its deletion mutant lacking 26 C-terminal residues, we probe the kinetics and thermodynamics of gp2.5 binding to ssDNA and double-stranded DNA (dsDNA). These force measurements allow us to determine the binding rate of both proteins to ssDNA, as well as their equilibrium association constants to dsDNA. …

Ralph L. Daniels V. Gamma West Brachytherapy Llc And John K. Hayes, M.D. : Brief Of Appellant, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

APPEAL FROM THE THIRD DISTRICT COURT, SALT LAKE COUNTY, STATE OF UTAH, THE HONORABLE ROBIN W. REESE PRESIDING

Multimedia Mathematics Intervention For Math-Delayed Middle School Students, Lisa L. Stokes

LSU Doctoral Dissertations

The purpose of this study is to determine if the Sharpening Math Skills Lab technology-mediated mathematics instructional practices for math-delayed middle school students have positive effects on their mathematics achievement and spatial visualization ability and to gauge student engagement in learning, implementation of the principles of instructional design, and attitudes toward mathematics instruction. The results of a recent meta-analysis report a range of significantly positive to significantly negative effect sizes which establish a need for further evaluation of academic achievement utilizing technology-mediated mathematics programs at the middle school level (Slavin, Lake, & Groff, 2007). The literature (Moreno & Mayer, 2000) …

The Influence Of Timed Reading Practices On Reading Gains And Comprehension Levels Of Third Grade Readers, Kristi D. Stuck

Theses and Dissertations

Since the signing of the No Child Left Behind (NCLB) Act, the Dynamic Indicators of Basic Early Literacy Skills (DIBELS) has been used by many schools to document students' reading gains. The purpose of the study was to investigate the influence of timed reading practices on the reading levels and comprehension scores of third grade students as they participated in literature discussion groups. Data collection included: reading levels from Developmental Reading Assessment, students' reading reflection logs, and transcriptions of language patterns during literature discussion groups. The findings revealed no statistical significance for students who participated in timed reading drills in …

Msp Possible Strands Framework, Maya Isabel Lazzaro, Mathematics And Science Partnerships

Long Term Ecological Research Network

Document of "Possible Strands Framework" 2008

Includes Essential Tasks for Year 1 and Suggested Activities at PI Meeting.

Differences In Methamphetamine Users And Crack Cocaine Users, Kilby Erwin Raptopoulos

Theses and Dissertations

This research addresses basic differences between crack cocaine users and methamphetamine users. The sample consisted of stimulant users who tested positive for either crack cocaine and/or methamphetamine from three rural counties in eastern Arkansas. This study seeks to further existing knowledge concerning drug use by examining demographics, drug use patterns, criminal histories and parental substance abuse. The study used Respondent-Driven Sampling to accumulate a sample size of 211 participants. Data was obtained through self-reported demographic information, drug use, criminal histories, and parental substance abuse problems during individual interviews, which were also matched with the results from a urinary analysis to …

Methods In Industrial Biotechnology For Chemical Engineers, Florentin Smarandache, W.B. Vasantha Kandasamy

Branch Mathematics and Statistics Faculty and Staff Publications

Industrial Biotechnology is an interdisciplinary topic to which tools of modern biotechnology are applied for finding proper proportion of raw mix of chemicals, determination of set points, finding the flow rates etc., This study is significant as it results in better economy, quality product and control of pollution. The authors in this book have given only methods of industrial biotechnology mainly to help researchers, students and chemical engineers. Since biotechnology concerns practical and diverse applications including production of new drugs, clearing up pollution etc. we have in this book given methods to control pollution in chemical industries as it has …

Cultural Advantages In China: Tale Of Six Cities, Florentin Smarandache, Fu Yuhua, Victor Christianto

Branch Mathematics and Statistics Faculty and Staff Publications

Nowadays, plenty of factories from Europe and other developed countries have been relocated to this country, considering its tremendous economic scale and rapid growth rate during the past three decades. But most of what happens inside the China nowadays is deeply hidden from the outside world (“the foreigners” as China people would call). This fact is partly because most reports on China were written by the so‐called fly‐high experts who are busy completing their reports despite a busy schedule. Very few books or reports were written by people inside, or at least “foreigners” who spent a few years in China. …

Advancing Epidemiological Science Through Computational Modeling: A Review With Novel Examples, Scott M. Duke-Sylvester, Eli N. Perencevich, Jon P. Furuno, Leslie A. Real, Holly Gaff

Biological Sciences Faculty Publications

Computational models have been successfully applied to a wide variety of research areas including infectious disease epidemiology. Especially for questions that are difficult to examine in other ways, computational models have been used to extend the range of epidemiological issues that can be addressed, advance theoretical understanding of disease processes and help identify specific intervention strategies. We explore each of these contributions to epidemiology research through discussion and examples. We also describe in detail models for raccoon rabies and methicillin-resis-tant Staphylococcus aureus, drawn from our own research, to further illustrate the role of computation in epidemiological modeling.

Ancient Dna Identification Of Early 20th Century Simian T-Cell Leukemia Virus Type 1, Sebastien Calvignac, Jean-Michel Terme, Shannon M. Hensley, Pierre Jalinot, Alex D. Greenwood, Catherine Hanni

Biological Sciences Faculty Publications

The molecular identification of proviruses from ancient tissues (and particularly from bones) remains a contentious issue. It can be expected that the copy number of proviruses will be low, which magnifies the risk of contamination with retroviruses from exogenous sources. To assess the feasibility of paleoretrovirological studies, we attempted to identify proviruses from early 20th century bones of museum specimens while following a strict ancient DNA methodology. Simian T-cell leukemia virus type 1 sequences were successfully obtained and authenticated from a Chlorocebus pygerythrus specimen. This represents the first clear evidence that it will be possible to use museum specimens to …

Genome-Wide Compensatory Changes Accompany Drug-Selected Mutations In The Plasmodium Falciparum Crt Gene, Hongying Jiang, Jigar J. Patel, Ming Yi, Jianbing Mu, Jinhui Ding, Robert Stephens, Roland A. Cooper, Michael T. Ferdig, Xin-Zhuan Su

Biological Sciences Faculty Publications

Mutations in PfCRT (Plasmodium falciparum chloroquine-resistant transporter), particularly the substitution at amino acid position 76, confer chloroquine (CQ) resistance in P. falciparum. Point mutations in the homolog of the mammalian multidrug resistance gene (pfmdr1) can also modulate the levels of CQ response. Moreover, parasites with the same pfcrt and pfmdr1 alleles exhibit a wide range of drug sensitivity, suggesting that additional genes contribute to levels of CQ resistance (CQR). Reemergence of CQ sensitive parasites after cessation of CQ use indicates that changes in PfCRT are deleterious to the parasite. Some CQR parasites, however, persist in the …

Using Rna Interference To Determine The Role Of Varisin In The Innate Immune System Of The Hard Tick Dermacentor Variabilis (Acari: Ixodidae)., Wayne L. Hynes, Martha M. Stokes, Shannon M. Hensley, S. Michelle Todd, Daniel E. Sonenshine

Biological Sciences Faculty Publications

Defensins are an important component of the innate immune system of ticks. These small peptides are produced by various genera of ticks, and expressed in various tissues. In this study we used RNA interference to silence the expression of the defensin varisin produced by the hemocytes of the American dog tick, Dermacentor variabilis. Ticks were injected with double stranded varisin RNA prior to being placed on a rabbit. After feeding, the ticks were removed, bled, and the hemolymph plasma and hemocytes separated. Hemocytes were screened for the presence (or absence) of both varisin transcript and peptide. Varisin peptide was …

Swimming Dynamics And Propulsive Efficiency Of Squids Throughout Ontogeny, Ian K. Bartol, Paul S. Krueger, Joseph T. Thompson, William J. Stewart

Biological Sciences Faculty Publications

Synopsis Squids encounter vastly different flow regimes throughout ontogeny as they undergo critical morphological changes to their two locomotive systems: the fins and jet. Squid hatchlings (paralarvae) operate at low and intermediate Reynolds numbers (Re) and typically have rounded bodies, small fins, and relatively large funnel apertures whereas juveniles and adults operate at higher Re and generally have more streamlined bodies, larger fins, and relatively small funnel apertures. These morphological changes and varying flow conditions affect swimming performance in squids. To determine how swimming dynamics and propulsive efficiency change throughout ontogeny, digital particle image velocimetry (DPIV) and kinematic …

Mycobacteriosis-Associated Mortality In Wild Striped Bass (Morone Saxatilis) From Chesapeake Bay, Usa, D. T. Gauthier, R. J. Latour, D. M. Heisey, C. F. Bonzek, J. Gartland, E. J. Burge, W. K. Vogelbein

Biological Sciences Faculty Publications

The striped bass (Morone saxatilis) is an economically and ecologically important finfish species along the Atlantic seaboard of the United States. Recent stock assessments in Chesapeake Bay (USA) indicate that non-fishing mortality in striped bass has increased since 1999, concomitant with very high (>50%) prevalence of visceral and dermal disease caused by Mycobacterium spp. Current fishery assessment models do not differentiate between disease and other components of non-fishing mortality (e. g., senescence, predation); therefore, disease impact on the striped bass population has not been established. Specific measurement of mortality associated with mycobacteriosis in wild striped bass is …

The Flora Of Kalabak Basin (Eskişehir, Turkey), Ati̇la Ocak, Gürbüz Hüner, Ebru Ataşlar

Turkish Journal of Botany

The present study is concerned with the flora of the Kalabak Basin, an area lying to the south-west of the city of Eskişehir that supplies Eskişehir with drinking water. As a result of our evaluation of the plant specimens collected over 3 years (2001 to 2003), 71 families, as well as 575 taxa belonging to 307 genera, were determined to occur in the study area (569 species, 3 subspecies, and 3 varieties). Two of these taxa belong to Pteridophytes, 5 belong to Gymnosperms, and 568 belong to Angiosperms (488 Dicotyledons, 80 Monocotyledons) subdivisions. The largest families are Asteraceae (80), Fabaceae …

Plant Health In Private Urban Gardens, Stephan Helfer

Turkish Journal of Botany

Private garden plots present a vast area for growing plants for food or enjoyment. The Royal Botanic Garden Edinburgh provides a plant identification and advisory service to the public. This includes a service to advise on plant health problems, which is not advertised. In the past 17 years a moderate number of individuals made use of this service, with an average of 67 enquiries and some 100 specimens per year. Relevant data from the enquiries were entered into a database and analysed. The majority of enquiries concerned tree problems, followed by ornamental and fruit plant problems. Fungi ranked highest, with …

Cover And Contents

Turkish Journal of Botany

No abstract provided.

Novel Approach For Synthesis Of 2:1 Permethylated Β-Cyclodextrin–C60 Conjugate, Zhu Guan, Yali Wang, Yong Chen, Yongmin Zhang

Department of Chemistry: Dissertations, Theses, and Student Research

Amphiphilic cyclodextrin–fullerene conjugates have potential biological activity, due to their water solubility. In order to study the influence of the linker of these conjugates on solubility and aggregation, a permethylated β-cyclodextrin–C₆₀ conjugate with a short linker –(CH₂)₂NHCO–, which is attached to the secondary face of β-cyclodextrin was synthesized. Its solubility in water and its UV spectrum in CH₂Cl₂ and water were investigated.

Timothy's Law: Introducing New York To Mental Health Parity, Desiree Busching, Simon Kapochunas

Hofstra Labor & Employment Law Journal

No abstract provided.

Micrornas (Mirnas) In Neurodegenerative Diseases, Peter T. Nelson, Wang-Xia Wang, Bernard W. Rajeev

Sanders-Brown Center on Aging Faculty Publications

Aging-related neurodegenerative diseases (NDs) are the culmination of many different genetic and environmental influences. Prior studies have shown that RNAs are pathologically altered during the inexorable course of some NDs. Recent evidence suggests that microRNAs (miRNAs) may be a contributing factor in neurodegeneration. miRNAs are brain-enriched, small (~22 nucleotides) non-coding RNAs that participate in mRNA translational regulation. Although discovered in the framework of worm development, miRNAs are now appreciated to play a dynamic role in many mammalian brain-related biochemical pathways, including neuroplasticity and stress responses. Research about miRNAs in the context of neurodegeneration is accumulating rapidly, and the goal of …

Providing A Safe Harbor For Those Who Play By The Rules: The Case For A Strong Regulatory Compliance Defense, Richard C. Ausness, H. Lee Barfield, David A. King, Joshua R. Denton, Stephen J. Jasper

Law Faculty Scholarly Articles

On September 25, 2003, a fire broke out at the National Health Care (NHC) nursing home facility in Nashville, Tennessee, causing sixteen deaths and a number of injuries from smoke inhalation. Thirty-two victims subsequently filed suit against the nursing home, alleging that NHC was negligent for failing to install sprinklers in its facility. This claim was made notwithstanding the fact that applicable federal, state, and local safety regulations did not require the installation of sprinklers in this particular type of building, and notwithstanding that the NHC facility had been inspected by state fire inspectors just months before the fire and …

Basic Governing Documents, Effective 2008-01-01, University Of Dayton

University Governing Documents

No abstract provided.

Tak1 Is Required For The Survival Of Hematopoietic Cells And Hepatocytes In Mice, Minghui Tang, Xudong Wei, Yinshi Guo, Peter Breslin, Shubin Zhang, Shanshan Zhang, Wei Wei, Zhenbiao Xia, Manuel Diaz, Shizuo Akira, Jiwang Zhang

Biology: Faculty Publications and Other Works

Transforming growth factor beta-activated kinase 1 (TAK1), a member of the MAPKKK family, is a key mediator of proinflammatory and stress signals. Activation of TAK1 by proinflammatory cytokines and T and B cell receptors induces the nuclear localization of nuclear factor kappaB (NF-kappaB) and the activation of c-Jun N-terminal kinase (JNK)/AP1 and P38, which play important roles in mediating inflammation, immune responses, T and B cell activation, and epithelial cell survival. Here, we report that TAK1 is critical for the survival of both hematopoietic cells and hepatocytes. Deletion of TAK1 results in bone marrow (BM) and liver failure in mice …

Negligence In The Air? Should Alternative Liability Theories Apply In Lead Paint Litigation?, John S. Gray, Richard O. Faulk

Pace Environmental Law Review

No abstract provided.

Organic Plus: Regulating Beyond The Current Organic Standards , Kate L. Harrison

Pace Environmental Law Review

No abstract provided.

Morehead Normal School To Morehead State University: Miscellaneous Information, Rowan County Historical Society.

Rowan County Histories Collection

Consists of a collection of photographs, newspaper clippings, and records related to the history of Morehead State University.

Analysis Of The N-Glycans Of Recombinant Human Factor Ix Purified From Transgenic Pig Milk, Geun-Cheol Gil, William H. Velander, Kevin E. Van Cott

Department of Chemical and Biomolecular Engineering: Faculty Publications

Glycosylation of recombinant proteins is of particular

importance because it can play significant roles in the

clinical properties of the glycoprotein. In this work, the

N-glycan structures of recombinant human Factor IX (tg-

FIX) produced in the transgenic pig mammary gland were

determined. Themajority of theN-glycans of transgenic pigderived

Factor IX (tg-FIX) are complex, bi-antennary with

one or two terminal N-acetylneuraminic acid (Neu5Ac) moieties.

We also found that the N-glycan structures of tg-FIX

produced in the porcine mammary epithelial cells differed

with respect to N-glycans from glycoproteins produced in

other porcine tissues. tg-FIX contains …

Earthworms And Acos: Determining A Preference For Cover Board Designs In Temperate Forests, Marie F. Schneider, Harry M. Tiebout Iii

Biology Student Work

No abstract provided.