Digital Commons Network^™

Review Of Syphilis Patient Records In İzmir State Venereal Diseases Clinic From 1994 To 2004, Meltem Işikgöz Taşbakan, Hüsnü Pullukçu, Şebnem Şenol, Tansu Yamazhan, Levent Kidak, Deni̇z Gökengi̇n

Turkish Journal of Medical Sciences

Aim: The aim of this study was to evaluate patients attending a sexually transmitted infection (STI) outpatient clinic with a presumptive or definitive diagnosis of syphilis with regard to demographic characteristics, clinical findings, diagnostic criteria, treatment regimens and follow-up data over a 10-year period. Materials and Methods: The records of patients who had a presumptive/definitive diagnosis of syphilis [according to Centers for Disease Control (CDC) criteria] and who were referred to the İzmir State Venereal Diseases Outpatient Clinic or who were diagnosed in the clinic between 1994 and 2004 were reviewed retrospectively. Results: A total of 689 patients were included …

Production Of Syllable Stress In Speakers With Autism Spectrum Disorders, Rhea Paul, Nancy Bianchi, Amy Augustyn, Ami Klin, Fred Volkmar

Communication Disorders Faculty Publications

This paper reports a study of the ability to reproduce stress in a nonsense syllable imitation task by adolescent speakers with autism spectrum disorders (ASD), as compared to typically developing (TD) age-mates. Results are reported for both raters’ judgments of the subjects’ stress production, as well as acoustic measures of pitch range and duration during stressed and unstressed syllable production. Results reveal small but significant differences between speakers with ASD and typical speakers in both perceptual ratings of stress and instrumental measures of duration of syllables. The implications of these findings for understanding prosodic deficits in ASD are discussed.

Auditory Processing Disorder, Rhea Paul

Communication Disorders Faculty Publications

A response from the editor is presented in response to a question on on the nature of auditory processing disorder (APD) in children.

Velo-Cardio-Facial Syndrome: 30 Years Of Study, Robert J. Shprintzen

Communication Disorders Faculty Publications

Velo-cardio-facial syndrome is one of the names that has been attached to one of the most common multiple anomaly syndromes in humans. The labels DiGeorge sequence, 22q11 deletion syndrome, conotruncal anomalies face syndrome, CATCH 22, and Sedlačková syndrome have all been attached to the same disorder. Velo-cardio-facial syndrome has an expansive phenotype with more than 180 clinical features described that involve essentially every organ and system. The syndrome has drawn considerable attention because a number of common psychiatric illnesses are phenotypic features including attention deficit disorder, schizophrenia, and bipolar disorder. The expression is highly variable with some individuals being essentially …

Neural Tube Defects And 19 Bp Deletion Within Intron-1 Of Dihydrofolate Reductase Gene, Nejat Akar, Ece Akar, Yonca Eği̇n, Gülhi̇s Deda, Saadet Arsan, Mesi̇ha Eki̇m

Turkish Journal of Medical Sciences

Aims: Dihydrofolate reductase (DHFR) is necessary for the reduction of the ingested folates before they are used in the body metabolism. Thus, the DHFR enzyme has an important role in folate supplementation and the DHFR gene is a strong candidate for a teratogenic locus for neural tube defects (NTDs). There is a 19 bp deletion within the first intron of the DHFR gene, which may have an effect on folate reduction. We thus studied this mutation in Turkish spina bifida patients and their mothers to determine whether there is an association with the occurrence of NTD. Materials and Methods: The …

Pten Expression In Primary Prostate Carcinoma In Turkish Patients, Di̇lek Ertoy Baydar, Haluk Özen, Osman Saraçbaşi, Erdem Karabulut

Turkish Journal of Medical Sciences

Aim: Prostatic adenocarcinoma shows remarkable variability in the incidence and biological behavior between populations from different races and geographical regions of the world. PTEN has been reported as the most commonly mutated tumor suppressor gene in prostate cancer. Incidence of PTEN alterations occurring in prostatic carcinoma has not been studied previously in the Turkish population. Materials and Methods: We examined PTEN protein expression immunohistochemically and its significance in 69 primary prostate cancer patients from Turkey. Two tissue microarrays constructed by 0.6 mm cores from radical prostatectomy specimens were used. Clinical information for all patients was obtained from hospital records. Results: …

Oxidative Stress Of Radioiodine Treatment In Patients With Hyperthyroidism, Mustafa Yildiz, Ekrem Çi̇çek, Burçi̇n Aşkim Gümüş, Celal Çerçi̇, Süreyya Çerçi̇, Erol Eroğlu, Namik Deli̇baş

Turkish Journal of Medical Sciences

Aims: To investigate radiation-induced oxidative damage in erythrocytes after administration of radioiodine-131 (^{131}I) in patients with hyperthyroidism. Materials and Methods: Twenty patients with hyperthyroidism (11 F, 9 M) treated with ^{131}I were included into the study. Blood samples were taken from patients just before, 1 hour after and 3 hours after applying radioiodine. Malondialdehyde (MDA) and levels of antioxidant enzymes such as glutathione peroxidase (GPX), superoxide dismutase (SOD) and catalase (CAT) were measured to evaluate the radiation-induced oxidative damage. Results: We found that enzyme activities of SOD, GPX and CAT were decreased 1 hour and 3 hours after radioiodine treatment …

Functional Vitamin B12 Deficiency Represented By Elevated Urine Methylmalonic Acid Levels In Patients With Migraine, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe, Hakan Tekeli̇, Mehmet Güney Şenol

Turkish Journal of Medical Sciences

Aims: Although vitamin B12 is currently used as a treatment option in patients with migraine, a possible cobalamin deficiency in those patients has not yet been investigated. In this study, we aimed to investigate cobalamin metabolism in patients with migraine. Materials and Methods: Fifty women having migraine without aura were matched with healthy controls (n=6) with the same age distribution. Fasting serum vitamin B12, folate, plasma total homocysteine (tHcy) and first morning urine methylmalonic acid (MMA) levels were determined in patient and control groups. Statistical differences in laboratory parameters between patient and control groups were analyzed by SPSS for Windows …

Serum Transforming Growth Factor-Β (Tgf-Β), Matrix Metalloproteinase-2 (Mmp-2), Matrix Metalloproteinase-9 (Mmp-9) And Tissue Inhibitors Of Metalloproteinase (Timp-1) Levels In Childhood Asthma, Fi̇gen Doğu, Ali̇şan Yildiran, Deni̇z Güloğlu, Funda Erol Çi̇pe, Mutlu Yüksek, Emel Babacan, Aydan İki̇nci̇oğullari

Turkish Journal of Medical Sciences

Aims: Airway remodelling is a characteristic feature of asthma and is a dynamic process involving extracellular matrix (ECM) production and its degradation. In this regard, the matrix metalloproteinases (MMPs) and their specific inhibitors known as tissue inhibitors of metalloproteinases (TIMPs) have been shown to be important in this process. In the present study, transforming growth factor (TGF)-\beta, MMP-2, MMP-9 and TIMP-1 levels in serum samples of children with stable asthma and healthy controls were evaluated to determine whether these levels show any difference between asthmatic and healthy children and whether or not these levels change with atopic status. Materials and …

Hematological Complications In 787 Cases Of Acute Brucellosis In Eastern Turkey, İmdat Di̇lek, Ahmet Durmuş, Mustafa Kasim Karahocagi̇l, Hayretti̇n Akdeni̇z, Hasan Karsen, Ali̇ İrfan Baran, Ömer Evi̇rgen

Turkish Journal of Medical Sciences

Aim: In this paper, we present the hematological findings of 787 cases diagnosed with acute brucellosis. Materials and Methods: Records of the cases seen between 1994 and 2006 were retrospectively investigated regarding hematological changes. Results: Three hundred sixty-five (46%) patients were male and 422 (54%) were female. Mean age was 32 (range: 11-78 years). Mean hematological values were as follows: Hb 12 g/dl (4-19), Htc 36% (12-56), leukocyte 6.9 x 10^9/L (0.5-25) and platelets 213 x 10^9/L (9-617). According to differential counts, 34% and 14% of patients had mononuclear cell and neutrophil dominance, respectively. Fifty-six percent of patients were found …

Classification Of Sigmoid Volvulus, S. Selçuk Atamanalp, Bülent Aydinli, Gürkan Öztürk, Mahmut Başoğlu, M. İlhan Yildirgan, Durkaya Ören, Abdul Meci̇t Kantarci

Turkish Journal of Medical Sciences

Aim: The aim of this study was to establish a classification that will aid in the surgical treatment and prognosis of sigmoid volvulus (SV). Materials and Methods: The records of 420 patients with SV who were treated surgically during a 41.5-year period were reviewed retrospectively. The preoperative and operative criteria that were significantly correlated with mortality were determined. Results: Of 420 patients, 68 (16.2%) died. Age over 60 years (P < 0.001), associated disease (P < 0.001), presence of shock (P < 0.001), and presence of sigmoid colon gangrene (P < 0.001) were significantly correlated with mortality. A classification was made using these criteria. Conclusions: Recommended treatment options and potential mortality rates were determined for each class in the new classification based on the evaluation of the present series, our clinical experience, and literature findings. This classification may be helpful in determination of the surgical treatment and prognosis of SV.

Abnormal Uterine Bleeding In Adolescents: Treatment With Combined Oral Contraceptive Pills Is Effective Even In Hospitalized Patients With Bleeding Disorders, M. Meti̇n Altay, Ali̇ Haberal

Turkish Journal of Medical Sciences

Aims: To show the efficacy of oral contraceptive (OC) treatment for hospitalized adolescent patients with abnormal uterine bleeding (AUB). Materials and Methods: Thirty-one girls with AUB and anemia hospitalized within the last two years were included. The patients´ medical records were evaluated retrospectively. All patients were given combined OC containing 0.03 mg ethinyl estradiol plus 0.15 mg desogestrel according to a defined protocol. Results: Among 31 patients, 8 (25.8%) had bleeding disorders: 3 (9.7%) had factor VII deficiency, 3 (9.7%) thrombocytopenia, 1 (3.2%) factor VIII deficiency and 1 (3.2%) von Willebrand disease. Vaginal bleeding stopped in all patients within a …

A Study Of Learning Assessment Of Personal Hygiene Skills Of Mentally Retarded Individuals In Drop-In Day Care Services, Fi̇gen Ar, Esra Kiliç, Ayşegül Akbay Yarpuzlu

Turkish Journal of Medical Sciences

Aim: The aim of the study was to assess the success and efficiency of the training practices for acquisition of basic personal hygiene skills and behavior of hand washing and soiling in a relatively heterogeneous group of individuals receiving care from a drop-in day care/special education service. We also analyzed etiologies of the causes of discrepancies in learning behavior implying a need for differentiation of intellectually disabled individuals who are candidates for continuous long-term institutional medical care from those who can be integrated into the community through special education. Materials and Methods: The study included 30 participants with mental retardation …

Clinical And Rhinoscintigraphic Evaluation Of Oral Macrolides In The Management Of Sinonasal Polyposis, Emi̇ne Aydin, Hülya Ortapamuk, Hakan Korkmaz, Engi̇n Dursun, Adi̇l Eryilmaz, Güleser Saylam, Muharrem Dağli

Turkish Journal of Medical Sciences

Aim: To document the efficacy of low-dose long-term oral macrolide treatment in the management of sinonasal polyposis. The study was designed prospectively in a group of patients with sinonasal polyposis and negative history of surgery. Materials and Methods: Ten patients were administered roxithromycin (RXM) 150 mg/day single oral dose for eight weeks. All patients underwent Tc-99m rhinoscintigraphic evaluation of mucociliary activity and endoscopic evaluation before and after the treatments. Response to treatment, in terms of rhinoscintigraphic and endoscopic improvement, was assessed. Results: Of the 10 patients, 7 were male and 3 female, with an average age of 46 years (27-74). …

Lone Atrial Septal Aneurysm With Spontaneous Echo Contrast: An Increased Stroke Risk, Serpi̇l Demi̇rci̇, M. Cem Dönmez, Süleyman M. Aslan

Turkish Journal of Medical Sciences

Aims: The etiology of stroke in young adults may be challenging. After preliminary investigations, a cause is not established in about one-third of patients. Cardiovascular embolism has been recognized as the cause of unexplained stroke or transient ischemic attack in a relevant number of young stroke patients. Materials and Methods: A 39-year-old right-handed woman was admitted to hospital with a left-side weakness of sudden onset. Her personal and family history were unremarkable except for several episodes of left arm weakness lasting for less than 10 minutes. On cranial magnetic resonance imaging, a right frontotemporal infarction was observed. Results: Laboratory work-up …

Unexpected Complication Due To Shigella Flexneri In A Child: Acute Appendicitis, Cüneyt Tayman, Alparslan Tonbul, Emi̇n Mete, Ferhat Çatal, Burhan Köseoğlu

Turkish Journal of Medical Sciences

Acute bacillary dysentery (shigellosis) occurs due to infections with shigella sp. The spectrum of acute shigellosis ranges from mild watery diarrhea to severe dysentery. Surgical complications of shigellosis described in children have included appendicitis with or without perforation, colonic perforation, intestinal obstruction, and intraabdominal abscess. Acute appendicitis and infective diarrheal illness can be difficult to differentiate, particularly in children. Thus, patients must be followed up closely until the differentiation between bacterial gastroenteritis and acute appendicitis can be made. We report herein a 10-year-old boy who had acute appendicitis due to Shigella flexneri.

Dermatomyositis Associated With Hemophagocytic Syndrome: A Case Report/Review Of The Literature, Engi̇n Sennaroğlu, Berçem Ayçi̇çek Doğan, Hasan Tunca, Bariş Yilmaz, Gamze Gedi̇k, Burak Ci̇velek, Si̇nem Tümtürk

Turkish Journal of Medical Sciences

Hemophagocytic syndrome (HPS) is a disorder that might be transferred genetically due to an autosomal recessive genetic defect of the long arm of chromosome 9 and chromosome 10 (9q21.3-22 and 10q21-22), termed as primary hemophagocytic syndrome (PHPS) or familial hemophagocytic hemophagocytosis (FHPS) and it may be associated with a variety of infections, malignant neoplasms, drugs, autoimmune diseases and various immuno deficiencies, termed as secondary hemophagocytic syndrome (SHPS). For most patients with HPS, the outcome is rapid and fatal unless the diagnosis is made early and followed by prompt therapeutic intervention. Fever, hepatosplenomegaly, cytopenia, hypertriglyceridemia and/or hypofibrinogenemia, low erythrocyte sedimentation rate, …

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Sehat-4: Class 4: Teacher's Guide, Tashmin Kassam-Khamis, Farah Shivji, Sadia Muzaffar Bhutta

Books

No abstract provided.

Sensitivity Of Kinetoplastids To Aminoglycoside: Correlation With The 3’ Region Of The Small Subunit Rrna Gene, A. S. Hamad Elgazwy, Masoom M. Yasinzai

Turkish Journal of Biology

In vitro culture systems were used to assess the growth inhibition of kinetoplastids by a variety of aminoglycosides. The parasites were allowed to grow to the stationary phase in the presence of varying concentrations of the drugs. The IC-50 for every drug was calculated by comparison with the control. The sensitivity of various leishmanial strains to these drugs was in the order of: G418 > hygromycin > paromomycin > neomycin; however, under our assay conditions gentamycin and kanamycin were non-leishmanicidal. The effects of the drugs on the intracellular form of the parasite in the macrophage cell line were also tested. Other kinetoplastids, such …

Comparative Antioxidant Activity Of Some Edible Plants, Zaha A. El-Agbar, Ashok K. Shakya, Nooman A. Khalaf, Makbula Al-Haroon

Turkish Journal of Biology

Terminalia chebula, Salvia officinalis L., Calamintha incana, Thymus vulgaris L., Matricaria chamomilla, and Nigella sativa are commonly used spices. In the present study the methanolic extracts of these spices were evaluated for their antioxidant activity by the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging method. All the methanolic extracts showed significant antioxidant activity. The IC_{50} of the methanolic extracts ranged between 3.8 ± 0.1 and 168.8 ± 2.1 \mug/ml, and that of ascorbic acid was 8.6 ± 0.1 \mug/ml. The study revealed that the consumption of these spices could exert several beneficial effects by virtue of their antioxidant activity.

The Antioxidant Activity Of Some Medicinal Plants, Prateek Kumar Jain, Veerasamy Ravichandran, Simant Sharma, Ram. K. Agrawal

Turkish Journal of Biology

The antioxidant properties of the methanol extracts of 10 medicinal plants were evaluated with the DPPH (1,1-diphenyl-2-picryl hydrazyl) test, hydroxyl scavenging test, and lipid peroxidation assay. The methanol extract of Emblica officinalis was the most active according to the DPPH test, with an IC_{50} value of 7.92 ± 0.1 \mug/ml, followed by Asparagus racemosus, with an IC_{50} value of 9.28 ± 0.2 \mug/ml. The minimum free radical scavenging activity was shown by Zingiber officinale, with an IC_{50} value of 44.48 ± 1.8 \mug/ml. The hydroxyl radical scavenging activity of the methanolic extracts of various plants was as follows: Asparagus racemosus …

Sehat-4: Chothhi Class: Asatza Aur Sehat Ke Karkuno Ke Liye Aik Gaed, Tashmin Kassam-Khamis, Farah Shivji, Sadia Muzaffar Bhutta

Books

No abstract provided.

An Evaluation Of Visitor Decisions Regarding Alternative Transportation In Glacier National Park, Melissa Lynn Baker

Graduate Student Theses, Dissertations, & Professional Papers

In 2007, Glacier National Park implemented a free, voluntary shuttle bus system along the Going to the Sun Road. The first year of implementation of the transit system at Glacier National Park presented a unique opportunity to evaluate visitor behavior in national parks. One way that transportation mode choice has been understood is through the theory of planned behavior, which characterizes social behavior as the result of conscious, deliberate thought processes directly related to the behavior in question. This study examined the intersection of national park visitors' recreation experience preference and their decisions toward shuttle use in a national park. …

A Manual Of Expected Milestones In Childhood And Occupation-Based Interventions, Laura J. Rabenberg, Chere L. Vosberg

Occupational Therapy Capstones

The purpose of this scholarly project was to develop a manual for parents of children ages birth to five years. The manual includes significant milestones and provides age-appropriate activities which can be used to facilitate development.

A literature review was conducted to identify how play is used to achieve developmental milestones. Resources included journal articles and textbooks from the disciplines of occupational therapy, psychology, education, and medicine.

A manual for parents was created and consists of a discussion on the importance of play in development, expected milestones, occupation-based interventions, and resources regarding child development. This manual is intended for distribution …

Vol. 33, No. 1: Winter 2008, School Of Medicine & Health Sciences

North Dakota Medicine Archive

No abstract provided.

Greed, Guns And Grist: U.S. Military Assistance And Arms Transfers To Developing Countries, Elizabeth Powers

North Dakota Law Review

No abstract provided.

Representing Clients In Mediation: A Twenty-Question Preparation Guide For Lawyers, Karen K. Klein

North Dakota Law Review

No abstract provided.

Cupola, 2008, Western New England College

Yearbooks

Western New England University was founded in 1919 as the Springfield Division of Northeastern University. The senior yearbooks bore the name of Northeastern University in some way until 1953. The yearbook was given its present day title, The Cupola, in 1961. Yearbooks contain photos of graduating seniors, campus events, student clubs and organizations, faculty and staff, athletic teams and events, and other memorable occasions from the academic year.

Emergency Medical Treatment And Active Labor Act—One Of These Things Is Not Like The Other: The Error Of Applying State Medical Malpractice Limits To Damages Awarded Under The Emergency Medical Treatment And Active Labor Act, Kendra L. Berardi

Western New England Law Review

No abstract provided.