Digital Commons Network^™

Application Of The Emotional Intelligence Construct To College Student Binge Drinking, Jeffrey P. Dulko

Graduate Theses, Dissertations, and Problem Reports (ETD)

Although extensive research has been conducted in the area of college binge drinking, relatively little has been done to study differences among alcohol-related consequences. Some initial studies have shown that binge drinking and its consequences are associated with several emotional and interpersonal factors, but there has been no comprehensive examination of these relationships. The theory of emotional intelligence (EI) has been developed recently to study emotional and interpersonal factors as an integrated construct. Research of the relationship between alcohol and EI could provide a valuable base for which to design alcohol prevention programs that target improving emotional and interpersonal deficits …

The Cystic Fibrosis Transmembrane Conductance Regulator: Regulation By Hsp-90, Kevin Marrs

Theses and Dissertations (ETD)

The hypothesis of this project is that a functionally relevant association exists between CFTR and Hsp90. In testing this hypothesis, (a) the association of CFTR and Hsp90 is confirmed via crosslinking and immunoprecipitation of CFTR from stably transfected HEK-293 cells, electrophoretic separation of cross-linked proteins, and protein identification via SDS-PAGE, western blotting, and mass spectrometry. Also, this hypothesis is tested by (b) functionally assessing the effect of Hsp90 on CFTR function via Ussing chamber analysis, two-electrode voltage clamp analysis, preliminary in vivoanimal studies, and protein phosphorylation. The HEK-293 Flag-CFTR cells used in this study allows for a high degree …

Theoretical And Experimental Evaluation Of Spatial Resolution In A Variable Resolution X-Ray Computed Tomography Scanner, Roman Melnyk

Theses and Dissertations (ETD)

A variable resolution x-ray (VRX) computed tomography (CT) scanner can image objects of various sizes with greatly improved spatial resolution. The scanner employs an angulated discrete detector and achieves the resolution boost by matching the detector angulation to the scanner field of view (FOV) determined by the size of an object being imaged. A comprehensive evaluation of spatial resolution in an experimental version of the VRX CT scanner is presented in this dissertation. Two components of this resolution were evaluated – the pre-reconstruction spatial resolution, described by the detector presampling modulation transfer function (MTF), and the post-reconstruction spatial resolution, given …

Dna Binding Specificity Of Mu Transcription Factor C And Crystallization Of C : Dna Complex, Karthik Shanmugantham

Theses and Dissertations (ETD)

The lytic cycle of phage Mu is regulated by a transcriptional cascade consisting of early, middle and late transcription. The Mor protein is an activator of the middle promoter Pm and is encoded by the last gene of the early transcript. The C protein is an activator of the four late promoters Plys, PI, PP, and Pmom and is expressed from the middle transcript. Both Mor and C proteins bind an imperfect dyad-symmetry element just upstream and overlapping the –35 region of Pm and Plys respectively. The main aims of this study was, (1) To understand the binding specificity of …

Synthesis Of Novel Sulfonamide-Based Calpain Inhibitors And Their Potential As Anti-Tumor Agents, Jin Xu

Theses and Dissertations (ETD)

Calpain is a class of intracellular cytoplasmic cysteine proteases.1 The enzyme participates in different intracellular signaling pathways that are mediated by Ca2+.2 The two major isoforms of calpain universally distributed in most mammalian tissues are calpain 1 (µ-calpain) and calpain 2 (m-calpain). The exact in vivo function of the enzyme is not clear, but calpain has been implicated in a variety of physiological and pathological conditions,3 such as cancer, stroke, cardiac ischaemia, muscular dystrophy, cataract and Alzheimer’s disease. Calpain inhibitors are therefore of interest as therapeutic agents and as biomedical tools.

Several potent calpain inhibitors isolated from natural sources as …

Cardiopulmonary Predicators Of Dysfunctional Ventilator Weaning Response After Coronary Artery Bypass Graft, Annapoorna Mary

Theses and Dissertations (ETD)

Although the majority of coronary artery bypass graft (CABG) surgery patients are extubated within 6 to 8 hours following surgery, 20% to 40% of patients remain intubated 12 hours after surgery due to dysfunctional ventilator weaning response (DVWR). DVWR associated with increased morbidity and mortality (30% to 43%) following CABG surgery. Finding significant antecedence to predict DVWR could help to identify and prevent the complications from DVWR after CABG surgery. Literature review revealed that there is an association between cardiopulmonary indicators (CPI) and DVWR after CABG surgery. Cardiopulmonary indicators are the selected hemodynamic parameters that have an association with DVWR. …

The Legal Ethics Of Pediatric Research, Doriane Lambelet Coleman

Duke Law Journal

Since the mid- to late 1990s, the scientific and medical research community has sought to increase its access to healthy children for research protocols that involve harm or a risk of harm. This move reverses longstanding policy within that community generally to exclude healthy children from such protocols on the grounds that the research as to them is non-therapeutic, that they are particularly vulnerable to research-related abuses, and that they are unable themselves to give informed consent to their participation. The research community's new posture has been supported by prominent pediatric bioethicists who have argued that unless healthy children are …

Eddie Murray Sr.

African American Funeral Programs

No abstract provided.

The Long-Term Teratogenic Effect Of Prenatal Alcohol Exposure On The Somatosensory And Motor Cortex Of Rats, Tyson Chappell

Theses and Dissertations (ETD)

The primary goal of this dissertation was to examine the long-term effect of prenatal alcohol exposure (PAE) on the primary somatosensory (SI) and primary motor cortex (MI). For over 30 years, PAE has been shown to produce a triad of symptoms (growth deficits, craniofacial dysmorphologies and central nervous system disruptions) diagnosed as fetal alcohol syndrome (FAS) in children and adults. Since low to moderate levels of prenatal alcohol exposure are less likely to produce FAS symptoms in children, the term “PAE” in this dissertation typically refers to heavy/abusive/chronic levels of prenatal alcohol exposure (in humans this equates to 5+ drinks/per …

The Sunset Of Quality Control In Modern Trademark Licensing, Irene Calboli

Faculty Scholarship

Historically, based on the premise that trademark protection is about consumer welfare, trademark law has allowed trademark licensing only as long as licensors control the quality of the products bearing the licensed marks. Ever since its adoption, however, this rule has been difficult to enforce because it hinges on a concept that is ambiguous and difficult to frame in a legal context: quality control. Unsurprisingly, the consequence has been inconsistent case law and much uncertainty as to what represents valid licensing. In addition, in the past decades, courts have proven increasingly reticent to strictly apply this rule and have declared …

The Increased Use Of Reconciliation In Criminal Cases In Central Asia: A Sign Of Restorative Justice, Reform Or Cause For Concern, Cynthia Alkon

Faculty Scholarship

This statement sums up the challenges lawyers, courts, legislatures, and other policymakers face when discussing mediation, reconciliation, or the use of other process alternatives in criminal cases in Central Asia. First, many people in the legal community of Central Asia have different understandings about the types of criminal cases appropriate for referral to alternative processes in lieu of criminal prosecution. Second, many people in the Central Asian legal community have attitudes about victims, defendants, and certain types of crimes that differ significantly from the attitudes held by the legal communities in other countries of the world. For instance, in Central …

Investigating Web-Based Recruitment Sources: Employee Testimonials Vs Word-Of-Mouse, Greet Van Hoye, Filip Lievens

Research Collection Lee Kong Chian School Of Business

Although the internet has dramatically changed recruitment practices, many web-based recruitment sources have not yet been investigated. The present study examines the effects of web-based employee testimonials and web-based word-of-mouth (i.e., 'word-of-mouse') on organizational attraction. The source credibility framework is used to compare these company-dependent and company-independent recruitment sources. In a sample of potential applicants for a head nurse position, word-of-mouse was associated with higher organizational attractiveness than web-based employee testimonials. However, potential applicants were more attracted when testimonials provided information about individual employees than about the organization. Conversely, word-of-mouse was associated with higher organizational attractiveness and more organizational pursuit …

International New Ventures: Revisiting The Influences Behind The 'Born-Global' Firm, Terence P. C. Fan, Phillip Phan

Research Collection Lee Kong Chian School Of Business

There is a small but theoretically important literature on 'born-globals' or international new venture firms that positions itself in contrast to the more established sequential international entry literature. In this paper we examine the pattern of entry into international markets for a set of international new ventures and show that they need not be a distinct breed of firms, as previous research has portrayed. Absent a specific technological advantage, the decision for a new venture to internationalize at inception is influenced by the size of its home market and by its production capacity, as well as by cultural and economic …

Nonstationary Discrete Choice: A Corrigendum And Addendum, Peter C. B. Phillips, Sainan Jin, Ling Hu

Research Collection School Of Economics

We correct the limit theory presented in an earlier paper by Hu and Phillips [2004a. Nonstationary discrete choice. Journal of Econometrics 120, 103-138] for nonstationary time series discrete choice models with multiple choices and thresholds. The new limit theory shows that, in contrast to the binary choice model with nonstationary regressors and a zero threshold where there are dual rates of convergence (n1/4 and n3/4), all parameters including the thresholds converge at the rate n3/4. The presence of nonzero thresholds therefore materially affects rates of convergence. Dual rates of convergence reappear when stationary variables are present in the system. Some …

Incidental Trends And The Power Of Panel Unit Root Tests, Hyungsik Roger Moon, Benoit Perrron, Peter C. B. Phillips

Research Collection School Of Economics

The asymptotic local power of various panel unit root tests is investigated. The (Gaussian) power envelope is obtained under homogeneous and heterogeneous alternatives. The envelope is compared with the asymptotic power functions for the pooled t-test, the Ploberger and Phillips [2002. Optimal testing for unit roots in panel data. Mimeo] test, and a point optimal test in neighborhoods of unity that are of order n-1/4T-1 and n-1/2T-1, depending on whether or not incidental trends are extracted from the panel data. In the latter case, when the alternative hypothesis is homogeneous across individuals, it is shown that the point optimal test …

Building Social Trust: A Human Capital Approach, Fali Huang

Research Collection School Of Economics

Much evidence suggests individuals differ in their predisposition to cooperate, which is essentially a component of human capital. This paper examines the role of individual cooperative tendencies and their interactions with institutions in generating social trust; it also endogenizes cooperative tendencies using a human-capital investment model. Multiple equilibria and inefficiencies exist due to positive externalities. An innovative finding is that, when institutions are more effective in punishing defecting behaviors, more people invest in cooperative tendencies and hence the endogenous social trust is higher, though the equilibrium cooperative tendencies are lower. This paper provides a plausible explanation for many empirical and …

Building Social Trust: A Human Capital Approach, Fali Huang

Research Collection School Of Economics

Much evidence suggests individuals di¤er in their predisposition to cooperate, which is essentially a component of human capital. This paper examines the role of individual cooperative tendencies and their interactions with institutions in generating social trust; it also endogenizes cooperative tendencies using a human capital investment model. Multiple equilibria and ine¢ ciencies exist due to positive externalities. An innovative …nding is that, when institutions are more e¤ective in punishing defecting behaviors, more people invest in cooperative tendencies and hence the endogenous social trust is higher, though the equilibrium cooperative tendencies are lower. This paper provides a plausible explanation for many …

Creating Alternate In-Basket Forms Through Cloning: Some Preliminary Results, Filip Lievens, Frederik Anseel

Research Collection Lee Kong Chian School Of Business

Research on constructing alternate forms of assessment center exercises is very scarce. This study examines the effectiveness of a cloning procedure (incident isomorphic approach) for developing alternate forms of a computerized in-basket. In this approach, original and alternate items are essentially similar (they are based on the same critical incident), while being superficially different (they are situated in a different context). Results showed there was no significant difference between the overall in-basket score across the alternate forms. In addition, these overall scores correlated .66, with projected estimates for the full in-basket approaching .80. Implications and limitations of the use of …

Measurement Invariance Of The Pay Satisfaction Questionnaire Across Three Countries, Filip Lievens, Frederik Anseel, Michael M. Harris, Jacob Eisenberg

Research Collection Lee Kong Chian School Of Business

In recent years, pay satisfaction has been increasingly studied in an international context, prompting the importance of examining whether the Pay Satisfaction Questionnaire (PSQ) is invariant across countries other than the United States. This study investigated the measurement invariance across three countries, namely, the United States (N = 321), Belgium (N = 301), and Cyprus (N = 132). Results showed that the measurement structure of the PSQ was invariant across these different countries because there was no departure from measurement invariance in terms of factor form, factor pattern coefficients, factor variances, and factor covariances. These results show promise for the …

Black Feminist Autobiographical Inquiry Into The Experiences Of A Teen Mom, Advis Dell Wilkerson

College of Graduate Studies: Theses & Dissertations

Using Black feminist thought as the theoretical framework and autobiographical inquiry as methodology, I explored ways in which adversity fostered resiliency of character. Despite difficult circumstances, such as growing up in a poor, single-parent household and becoming pregnant in the 9th grade when continuing one's education after pregnancy or marriage was not permitted in the Deep South, with the help of others, I fought to finish my high school education and succeeded in college. I credit a close bond with a supportive adult and my own development of racial awareness with helping me to turn obstacles into successes. My intent …

Study Of The Implementation Of A Professional Learning Community In One Middle School In Georgia, Jana Maria Underwood

College of Graduate Studies: Theses & Dissertations

As public demands for school accountability continue to increase due to federal legislation such as the No Child Left Behind Act of 2001, educators struggle to meet rising minimum standards. In an effort to address these pressures and search for ways to improve, educators consider implementing a professional learning community model which focuses on the improvement of teaching and learning. While attributes and characteristics of professional learning communities are documented in the literature, little is known about how the model is established or sustained. The purpose of this case study was to understand how one middle school implemented a professional …

Elementary Teacher Mentoring In A Rural Georgia School System: The Impact On Teacher Retention And The Implication For Elementary School Principals, Sharon Renea Colson

College of Graduate Studies: Theses & Dissertations

The purpose of this study was to explore beginning teachers' beliefs on their mentoring programs and to explain their perspectives. Face-to-face interviews were conducted with three beginning teacher participants and three principal participants in a rural Georgia school system. Constant comparative analysis was used to collect, code, and analyze the data, which included interview responses and researchers' memos. Mentoring programs were found to be supportive practices which involved the beginning teachers and mentors. Beginning teachers formed open, positive relationships with their mentors and interacted with them on a regular basis through their mentoring experiences in their respective schools. These interactions …

Man Behind The Curtain: The 2004 Election From A Historical Perspective, Melissa Michelle Merritt

College of Graduate Studies: Theses & Dissertations

The 2004 election was a very contentious display of modern democracy. It illustrated that political candidates market themselves as though they were products to be bought from a store. By utilizing newspaper articles, autobiographies, and various other sources, this study seeks to show several things. First, it illustrates the evolution of presidential campaigns from the first contested election until the controversial 2000 election. Second, it traces the rise of the Christian Right. It then delves into the Cold War and the War on Terror as a continuation of the former. Finally, the study culminates with an examination of the 2004 …

Delta-Like 4 Notch Ligand Regulates Tumor Angiogenesis, Improves Tumor Vascular Function, And Promotes Tumor Growth In Vivo, J-L Li, Rca Sainson, W Shi, R Leek, Et Al

School of Biomedical Sciences

The vascular endothelial growth factor (VEGF) plays a key role in tumor angiogenesis. However, clinical trials targeting the VEGF pathway are often ineffective, suggesting that other factors/pathways are also important in tumor angiogenesis. We have previously shown that the Notch ligand Delta-like 4 (DLL4) is up-regulated in tumor vasculature. Here, we show that DLL4, when expressed in tumor cells, functions as a negative regulator of tumor angiogenesis by reducing the number of blood vessels in all five types of xenografts, but acts as a positive driver for tumor growth in two of them (human glioblastoma and prostate cancer). The growth …

Pq Evaluation Project Stage 1, H Donnellan, G Jack, J Grose, A Gilbert

School of Health Professions

No abstract provided.

A Consistent Characteristic Function-Based Test For Conditional Independence, Liangjun Su, Halbert White

Research Collection School Of Economics

Y is conditionally independent of Z given X if Pr{f(y|X,Z)=f(y|X)}=1 for all y on its support, where f(·|·) denotes the conditional density of Y given (X,Z) or X. This paper proposes a nonparametric test of conditional independence based on the notion that two conditional distributions are equal if and only if the corresponding conditional characteristic functions are equal. We extend the test of Su and White (2005. A Hellinger-metric nonparametric test for conditional independence. Discussion Paper, Department of Economics, UCSD) in two directions: (1) our test is less sensitive to the choice of bandwidth sequences; (2) our test has power …

Business Groups: An Integrated Model To Focus Future Research, Daphne W. Yiu, Yuan Lu, Garry D. Bruton, Robert E. Hoskisson

Research Collection Lee Kong Chian School Of Business

Business groups are the primary form of managing large business organizations outside North America. This paper provides a systematic and integrative framework for understanding business groups. We argue that existing theoretical perspectives of business groups pay attention to four critical external contexts, each of which draws from a specific theoretical perspective: market conditions (transaction cost theory), social relationships (relational perspective), political factors (political economy perspective), and external monitoring mechanisms (agency theory). Business groups adapt to these external forces by deploying various internal mechanisms along two key dimensions: one focuses on the distinctive roles of the group affiliates (horizontal connectedness) and …

Knowledge Narratives And Heterogeneity In Management Consultancy And Business Services, Robin Fincham, Timothy Adrian Robert Clark, Karen Handley, Andrew Sturdy

Research Collection Lee Kong Chian School Of Business

In the professional services, diversification into various types of business advice has implications for knowledge boundaries. This is a sector of changing jurisdictional patterns and periodic reconstruction. Firms like large law practices that feed services into corporate clients have been merging to provide global coverage (Suddaby and Greenwood, 2001; Suddaby et al., 2004). But new specialisms in areas like consulting and IT are even more dynamic. Patterns such as the growth in outsourcing and movement into management consulting accounted for stupendous growth of the global accounting firms. These changes have themselves been overtaken, as the IT and systems giants muscled …

Dry Beans, Unknown Unknown

All Current Publications

This fact sheet lists details of dry bean crop insurance.

Corn, Unknown Unknown

All Current Publications

This fact sheet lists details of corn crop insurance.