Digital Commons Network^™

January 6, 2007 (Pages 1-184), Pennsylvania Legislative Reference Bureau

Volume 37 (2007)

No abstract provided.

Campus Report, Vol. 34, No. 5, University Of Dayton

Campus Report

"Two-faced racism": Research by a UD professor finds widespread racist language and attitudes among white college students in private.

Volume Cxxiv, Number 9, January 5, 2007, Lawrence University

The Lawrentian

No abstract provided.

The Elms 2007, Buffalo State College

Elms, Student Yearbooks

Buffalo State's annual yearbook "The Elms".

Please refer to our copyright statement for more information.

Note: Please bear in mind that the college has always been a part of the surrounding society, sharing in the attitudes and practices of the day. Thus these historical records may on occasion contain material that today would be considered offensive or inappropriate.

Γ-Tocotrienol Inhibits Nuclear Factor-Κb Signaling Pathway Through Inhibition Of Receptor-Interacting Protein And Tak1 Leading To Suppression Of Antiapoptotic Gene Products And Potentiation Of Apoptosis, Seok Ahn Kwang, Gautam Sethi, Koyamangalath Krishnan, Bharat B. Aggarwal

ETSU Faculty Works

Unlike the tocopherols, the tocotrienols, also members of the vitamin E family, have an unsaturated isoprenoid side chain. In contrast to extensive studies on tocopherol, very little is known about tocotrienol. Because the nuclear factor-κB (NF-κB) pathway has a central role in tumorigenesis, we investigated the effect of γ-tocotrienol on the NF-κB pathway. Although γ-tocotrienol completely abolished tumor necrosis factor α (TNF)-induced NF-κB activation, a similar dose of γ-tocopherol had no effect. Besides TNF, γ-tocotrienol also abolished NF-κB activation induced by phorbol myristate acetate, okadaic acid, lipopolysaccharide, cigarette smoke, interleukin-1β, and epidermal growth factor. Constitutive NF-κB activation expressed by certain …

The Respite And Recreation: An Innovative Recreation Service To Adopted Children With Special Needs, Heewon Yang, Jennifer M. Howard

Journal of Youth Development

Often youth in the foster care system have traumatic experiences associated with abuse and separation from their biological family. These experiences may lead to emotional, psychological, and behavioral problems that challenge the new adoptive family dynamic. This article introduces the Respite and Recreation (R & R) program in a Midwestern area. R & R combines faculty, staff, and graduate students from a local University, local community resources, and staff from a local adoption agency to provide recreation, respite, and professional support services for children with special needs and their adoptive parents. The R & R program provides the adopted children …

The Respite And Recreation: An Innovative Recreation Service To Adopted Children With Special Needs, Heewon Yang, Jennifer M. Howard

Journal of Youth Development

Often youth in the foster care system have traumatic experiences associated with abuse and separation from their biological family. These experiences may lead to emotional, psychological, and behavioral problems that challenge the new adoptive family dynamic. This article introduces the Respite and Recreation (R & R) program in a Midwestern area. R & R combines faculty, staff, and graduate students from a local University, local community resources, and staff from a local adoption agency to provide recreation, respite, and professional support services for children with special needs and their adoptive parents. The R & R program provides the adopted children …

The Weekly Challenger, January 4, 2007, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The January 4, 2007, issue of The Weekly Challenger.

A Bayesian Hierarchical Model For Constrained Distributed Lag Functions: Estimating The Time Course Of Hospitalization Associated With Air Pollution Exposure, Roger Peng, Francesca Dominici, Leah J. Welty

Johns Hopkins University, Dept. of Biostatistics Working Papers

Numerous time series studies have provided strong evidence of an association between increased levels of ambient air pollution and increased levels of hospital admissions, typically at 0, 1, or 2 days after an air pollution episode. An important research aim is to extend existing statistical models so that a more detailed understanding of the time course of hospitalization after exposure to air pollution can be obtained. Information about this time course, combined with prior knowledge about biological mechanisms, could provide the basis for hypotheses concerning the mechanism by which air pollution causes disease. Previous studies have identified two important methodological …

Most Popular Downloads -- December 2006

Institutional Repository Information

The 120 (or so) most-often-downloaded documents from the UNL Digital Commons for December 1 through December 31, 2006. Also total downloads and total discreet files downloaded for the period.

Reliability And The Interests Of Justice: Interpreting The Military Commissions Act Of 2006 To Deter Coercive Interrogations, Peter Margulies, Laura Corbin

Roger Williams University Law Review

No abstract provided.

Wintersession Classes Become Popular Alternative For Um Students, Staff Report

University of Mississippi News

OXFORD, Miss. - Completing college courses in a short, concentrated time has become a popular option on many campuses, including the University of Mississippi, where preliminary figures show 3,118 students are enrolled in Wintersession classes.

The Guardian, January 03, 2007, Wright State University Student Body

The Guardian Student Newspaper

Twenty page issue of The Guardian, the official student-run newspaper for Wright State University. The Guardian has been published regularly since March of 1965.

The Rhode Island General Assembly In The Defense Of Civil Liberties, Steven Brown

Roger Williams University Law Review

No abstract provided.

104 Publ L 208 Omnibus Consolidated Appropriations Act, 1997, U.S. Congress

Documents

No abstract provided.

Intellectual Property Management In Health And Agricultural Innovation: A Handbook Of Best Practices, Vol. 2, Anatole Krattiger, Richard T. Mahoney, Lita Nelsen, Jennifer A. Thomson, Alan B. Bennett, Kanikaram Satyanarayana, Gregory D. Graff, Carlos Fernandez, Stanley Kowalski

Law Faculty Scholarship

Prepared by and for policy-makers, leaders of public sector research establishments, technology transfer professionals, licensing executives, and scientists, this online resource offers up-to-date information and strategies for utilizing the power of both intellectual property and the public domain. Emphasis is placed on advancing innovation in health and agriculture, though many of the principles outlined here are broadly applicable across technology fields. Eschewing ideological debates and general proclamations, the authors always keep their eye on the practical side of IP management. The site is based on a comprehensive Handbook and Executive Guide that provide substantive discussions and analysis of the opportunities …

The Statesman, V. 42, I. 34, Stony Brook University

Stony Brook Statesman-Sucolian

v. 42, i. 34

Apparatus And Method For Growing Crystal, And Apparatus And Method For Analyzing Crystal: United States Patent No. 7,156,917 B2, Hideaki Moriyama, Norio Sugi, Kazunori Kawasaki, Shoji Muramatsu

Hideaki Moriyama Publications

An apparatus for growing a biological macromolecular crystal by vaporizing biological macromolecular solution into an oversaturated state. The apparatus includes a first sealed room that receives first crystallizing agent solution, and a communicating tube that communicates with the first sealed room and has a small sectional area for suppressing convection of air. A plurality of droplets of solution dissolving a biological macromolecule and a crystallizing agent therein are held in the communicating tube with the plurality of droplets being separated from each other.

High-Frequency Ultrasound Drug Delivery And Cavitation, Mario Alfonso Diaz

Theses and Dissertations

The viability of a drug delivery system which encapsulates chemotherapeutic drugs (Doxorubicin) in the hydrophobic core of polymeric micelles and triggers release by ultrasound application was investigated at an applied frequency of 500 kHz. The investigation also included elucidating the mechanism of drug release at 70 kHz, a frequency which had previously been shown to induce drug release. A fluorescence detection chamber was used to measure in vitro drug release from both Pluronic and stabilized micelles and a hydrophone was used to monitor bubble activity during the experiments. A threshold for release between 0.35 and 0.40 in mechanical index was …

The Effects Of Novel Serms On Endothelial And Epithelial Tumor Cell Estrogen Receptor Activation, Palvos Zacharias Kaimakliotis

Yale Medicine Thesis Digital Library

Premenopausal women are relatively protected against the development of coronary heart disease, when compared with age-matched men. This difference dissolves after menopause and is accepted to be hormonally mediated. Despite recent clinical controversies in the use of hormone replacement therapy in postmenopausal women, there have been numerous in vitro and in vivo studies that demonstrate favorable effects of estrogen on the endothelium. The Bender laboratory has shown that 17β-estradiol (E2) rapidly induces nitric oxide (NO) release from human endothelial cells (EC) in vitro. This occurs through a c-Src/phosphatidylinositol 3-kinase (PI3-kinase)/Akt pathway, in a rapid fashion in the absence of modulated …

Glycaemic Index, Glycaemic Load And Risk Of Endometrial Cancer: A Prospective Cohort Study, Stephanie A. Navarro Silvera, Thomas E. Rohan, Meera Jain, Paul D. Terry, Geoffrey R. Howe, Anthony B. Miller

Department of Public Health Scholarship and Creative Works

Objective

High-glycaemic-load diets may increase endometrial cancer risk by increasing circulating insulin levels and, as a consequence, circulating oestrogen levels. Given the paucity of epidemiological data regarding the relationship between the dietary glycaemic index and glycaemic load and endometrial cancer risk, we sought to examine these associations using data from a prospective cohort study.

Design, setting, and subjects

We examined the association between dietary glycaemic load and endometrial cancer risk in a cohort of 49 613 Canadian women aged between 40 and 59 years at baseline who completed self-administered food-frequency questionnaires between 1982 and 1985. Linkages to national mortality and …

Risk And Protective Factors For Children Of Adolescents: Maternal Depression And Parental Sense Of Competence, Lisa Knoche, Jami E. Givens, Susan M. Sheridan

Department of Educational Psychology: Faculty Publications

We investigated the relationship between depression and parental sense of competence to child cognitive outcomes for a sample of 49 adolescent mothers and their young children (Mean age = 9 1/2 months) enrolled in a student parenting program. Cognitive development of the infants and toddlers was assessed using the Bayley Scales of Infant Development. Maternal depression was assessed with the CES-D and parental competence measured with the Parental Sense of Competence Scale. Results indicated that maternal depression and parental sense of competence alone did not predict children’s cognitive scores; the interaction of the variables significantly predicted children’s outcomes. Mothers reporting …

Growth Factor Binding Molecules, Said Sebti, Andrew D. Hamilton

USF Patents

Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid sidechains. The growth factor binding molecules specifically bind various growth factors and are suitable for treating a subject having tumors or restinosis. In one embodiment a platelet-derived growth factor binding molecule is disclosed that is used to inhibit tumor growth and angiogenesis in solid tumors.

Sovereign Rights Oveer Indonesian Natural Resources: An Archipelagic Concept Of Rational And Sustainable Resource Management, Mochtar Kusumaatmadja

Indonesian Journal of International Law

This article is discussing about the problems in environmental, ecology, and oceanography, and the potential of South China Sea and the seas surroundings for the development of marine research and also for the environmental in that area protection.

Comparative Response Of Rams And Bulls To Long-Term Treatment With Gonadotropin-Releasing Hormone Analogs, H. Jiménez-Severiano, M. J. D'Occhio, D. D. Lunstra, M. L. Mussard, T. L. Davis, W. J. Enright, J. E. Kinder

Roman L. Hruska U.S. Meat Animal Research Center: Reports

The objective was to compare the relative response between rams and bulls in characteristics of LH, FSH and testosterone (T) secretion, during and after long-term treatment with GnRH analogs. Animals were treated with GnRH agonist, GnRH antagonist, or vehicle (Control) for 28 days. Serial blood samples were collected on day 21 of treatment, and at several intervals after treatment. Injections of natural sequence GnRH were used to evaluate the capacity of the pituitary to release gonadotropins during and after treatment. Treatment with GnRH agonist increased basal LH and T concentrations in both rams and bulls, with a greater relative increase …

Identification Of Genes Encoding Acyl-Coa Reductases And Aldehyde Reductases In Mycobacterial Genome By Characterization Of The Reductases Expressed In E. Coli, Harminder Singh

Electronic Theses and Dissertations

Mycobacterium tuberculosis has been long known to produce wax esters. However, the enzymes involved in their biosynthesis have not been identified. Here we report the identification of Rv3391 and Rv1543 as genes that encode fatty acyl-CoA reductases and Rv1544 as one that encodes an aldehyde reductase. When expressed in E.coli, the products of Rv3391 and Rv1543 catalyzed reduction of fatty acyl-CoA to fatty alcohol with the corresponding aldehyde as an intermediate with an optimal pH of 7.0. Both enzymes showed a strong preference for NADPH over NADH as a reductant. Apparent Km for NADPH was 38 [micro]M for Rv3391 product …

Social Pathogenic Sources Of Poor Community Health, Hayden Smith

Electronic Theses and Dissertations

The United States currently provides a health care system that is neither efficient nor equitable. Despite outspending the world on health care, over three-fourths of developed countries produce better health outcomes (Auerbach et al., 2000). Simultaneously, the "Ecological School of Thought" has documented the large impact that social, economic, and environmental circumstances play in health outcomes. Unfortunately, these 'ecological" studies are frequently conducted without theoretical justification, and rely solely on a cross-sectional research design and a myriad of unrelated variables. This study represents an important step towards the development of a true theory of "ecology". More specifically, we argue that …

Correlation Of Rpob Gene Mutation With Clinical Rifabutin And Rifampicin Resistance For Treatment Of Crohn's Disease, Daniel Beckler

Electronic Theses and Dissertations

Emerging rise in microbial drug resistance and the slow-growing characteristic of some intracellular pathogens such as MAP (Mycobacterium avium subspecies paratuberculosis) strongly urges the need for an effective approach for unconventional drug susceptibility testing. We designed a molecular-based PCR method for the evaluation of rifabutin (RFB) and rifampicin (RIF) resistance based on probable determinant regions within the rpoB gene of MAP, including the 81 bp variable site located between nucleotides 1363 and 1443. The minimum inhibitory concentration (MIC) for RIF was also determined against 10 MAP isolates in attempt to seek correlation with rpoB sequences. We determined that MAP strain …

Mechanism Of Action And Regulation Of Membrane Serine Protease Prostasin In The Prostate And Prostate Cancer, Mengqian Chen

Electronic Theses and Dissertations

The glycosylphosphatidylinositol (GPI)-anchored serine protease prostasin (PRSS8) is expressed at the apical membrane surface of epithelial cells and acts as a suppressor of tumor invasion when re-expressed in highly invasive human prostate and breast cancer cell lines. To better understand the molecular mechanisms underlying the anti-invasion phenotype associated with prostasin re-expression in prostate cancer cells, we expressed wild-type human prostasin or a serine active-site mutant prostasin in the PC-3 human prostate carcinoma cells. Molecular changes were measured at the mRNA and the protein levels. The expression of several invasion-promoting molecules is regulated by prostasin re-expression, mediated by a protein-level down-regulation …

A Member Of The Novel Fikk Family Of Plasmodium Falciparum Putative Protein Kinases Exhibits Diacylglycerol Kinase Activity And Is Exported To The Host Erythrocyte, David Floyd Curtis

Electronic Theses and Dissertations

Plasmodium falciparum is one of four species known to cause malaria in humans and is the species that is associated with the most virulent form of the disease. Malaria causes nearly two million deaths each year, many of these occurring among children in under-developed countries of the world. One reason for this is the prevalence of drug resistant strains of malaria that mitigate the efficacy of existing drugs. Hence, the identification of a new generation of pharmacological agents for malaria is extremely urgent. The recent identification of a group of novel protein kinases within the Plasmodium falciparum genome has provided …