Digital Commons Network^™

Applications Of Diffusion Maps In Gene Expression Data-Based Cancer Diagnosis Analysis, Rui Xu, Donald C. Wunsch, Steven Damelin

Electrical and Computer Engineering Faculty Research & Creative Works

Early detection of a tumor's site of origin is particularly important for cancer diagnosis and treatment. The employment of gene expression profiles for different cancer types or subtypes has already shown significant advantages over traditional cancer classification methods. One of the major problems in cancer type recognition-oriented gene expression data analysis is the overwhelming number of measures of gene expression levels versus the small number of samples, which causes the curse of dimension issue. Here, we use diffusion maps, which interpret the eigenfunctions of Markov matrices as a system of coordinates on the original data set in order to obtain …

Executive Function Differences In Medicated Depressed, Non-Medicated Depressed, And Non-Medicated Non-Depressed Individuals, Michael T. Ransom

Theses and Dissertations

The purpose of the current study was to assess the performance of depressed young adults on tests of executive function, while addressing the variables of age and medication status, which have been inconsistently measured in previous research. It was hypothesized that statistically significant group differences would occur on tests of executive functions in three distinct groups: medicated depressed, non-medicated depressed, and non-medicated non-depressed individuals.

Participants included 53 adults who were medicated depressed ( n = 15), non-medicated depressed (n = 16), and non-medicated non-depressed (n = 22) and were between the ages of 19 and 40 years. Participants completed measures …

Evaluating The Immediate Impact And Short-Term Therapeutic Effects Of The “Internalized-Other” Interviewing With Couples, Shai M. Brosh

Dissertations

The present study examined empirically the immediate and short-term therapeutic effects of the internalized-other interview (Tomm, 1996) with couples during a single session and compared it with the standard method of interviewing couples (i.e., treatment as usual). Thirty-two married couples (N = 64 participants) were randomly assigned into one of two conditions (internalized-other versus standard interviewing). Couples attended an initial interview session and two follow-ups (one and four-weeks respectively). Self-reported measures of session impact were taken immediately after the session, while self-reported measures of marital satisfaction, intimacy, closeness and empathy were taken at baseline (before the session) and during …

Work Stress, Non-Work Stress And Mental Health Among School-Based Speech-Language Pathologists: Effects Of Social Support, Lena Gloria Caesar

Dissertations

This study utilized secondary data from the Work and Well-being of SLPs survey (Caesar, 2004) to examine possible sources (predictors) of work stress, job satisfaction, and psychological distress among 409 speech-language pathologists (SLPs) employed in public school settings in Michigan. This study also investigated the relationship of work-related and non-work-related stress to the mental health status of SLPs and sought to determine the mediating and/or moderating effects of varied types of social support on the mental health of respondents. Data analysis was done in three stages. First, each of the dependent and independent variables were described statistically. Secondly, correlation analyses …

Private Narratives In Public Places: The Experiences Of Predominantly White Gay Male Undergraduates On Lgb Classroom Panels, James Patrick Dolan Jr.

Dissertations

The scholarly literature addresses the common practice and effectiveness of using classroom panel presentations by lesbian, gay, and bisexual (LGB) speakers to increase awareness of LGB experiences and to change attitudes. However, little is known about the experiences of the speakers themselves or how the experience may affect the speaker's sense of self or identity. From an identity as narrative perspective, the goal of this study was to learn what effect the repeated telling of a coming out story in a public setting may have on the teller's identity, the story they tell, and the meanings and feelings associated with …

An Investigation Of Successful And Unsuccessful Students’ Problem Solving In Stoichiometry, Ozcan Gulacar

Dissertations

In this study, I investigated how successful and unsuccessful students solve stoichiometry problems. I focus on three research questions: (1) To what extent do the difficulties in solving stoichiometry problems stem from poor understanding of pieces (domain-specific knowledge) versus students' inability to link those pieces together (conceptual knowledge)? (2) What are the differences between successful and unsuccessful students in knowledge, ability, and practice? (3) Is there a connection between students' (a) cognitive development levels, (b) formal (proportional) reasoning abilities, (c) working memory capacities, (d) conceptual understanding of particle nature of matter, (e) understanding of the mole concept, and their problem-solving …

Evaluation Of A School-Based Program Targeting Pediatric Asthma Self-Management Skills In An Urban Population, Dawn J. Dore-Stites

Dissertations

Asthma is the most commonly diagnosed chronic disorder in childhood and is linked with several problematic outcomes including frequent school absences, increased hospitalizations and decreased quality of life. Further, urban populations struggling with low socioeconomic status are disproportionately represented in prevalence statistics and suffer from increased functional morbidity relative to other children with asthma. These findings exist in the midst of largely effective pharmacological interventions.

Asthma self-management programs (SMPs) target several behaviors linked to improved outcomes and are often used as an adjunct to medication management. SMPs have been employed using a variety of techniques and treatment targets in a …

Wireless Passive Surface Acoustic Wave (Saw) Sensing System, Sridevi Krishnamurthy

Dissertations

Due to their small size and ruggedness, Surface Acoustic Wave (SAW) devices have been widely used as part of wireless sensing or identification system especially in inaccessible and inhospitable environments. In addition, SAW devices find widespread applications as filters in communication systems and also as physical, chemical and bio-sensors and ID tags. The passive wireless SAW sensing system mainly consists of a passive SAW sensor and an interrogation unit which sends a burst signal to the SAW sensor and processes the sensor response. Theobjectives of this work were designing, prototyping and fabricating the interrogation unit on a PCB and also …

The Effects Of Aging And Activity On Glial Cell Line-Derived Neurotrophic Factor Expression In Skeletal Muscle, Nathan Peplinski

Dissertations

Glial cell line-derived neurotrophic factor (GDNF) is an extracellular signaling protein that is produced by skeletal muscle and is important for the motor neurons that control muscle movement. GDNF has been shown to keep neurons alive under conditions that they would otherwise not persist. In skeletal muscle, GDNF has been shown to be one of the most potent neurotrophic factors that influence motor neuron survival. While the role of GDNF has been well studied during early development, not much is known about what happens to GDNF expression in the adult and with advanced aging. Previous results from our lab have …

The Law Of International Disaster Response: Overview And Ramifications For Military Actors, David Fisher

International Law Studies

No abstract provided.

A Retrospective Evaluation Of Crown-Fractured Permanent Teeth Treated In A Pediatric Dentistry Clinic, H. Cem Güngör, Serdar Uysal, Nil Altay

School of Dentistry Faculty Research and Publications

A retrospective study was carried out on the dental trauma records of 93 patients (55 boys, 38 girls) with 129 crown-fractured teeth. The patients’ average age was 9.57 years (SD 1.57), ranging between 7 and 15 years. Uncomplicated crown facture (comprising enamel–dentin) was the most observed type of injury (n = 107, 83%). Only 15 patients (16.13%) sought treatment in less than 24 h following the injury. Of 41 injured teeth (31.79%) the apices were open at the time of presentation at the clinic. The initial treatment of these injured teeth were interim restoration with acid-etch and composite (69%), …

Unitary Law Re-Form, Pluralistic Law Re-Substance: Illuminating Legal Change, Roderick A. Macdonald

Louisiana Law Review

No abstract provided.

Main Hall To Main Street, August 2007, University Of Montana--Missoula. Office Of University Relations

Main Hall to Main Street, 2005-2010

This is volume 13, number 8 of Main Hall to Main Street.

Assessment Of Genetic Diversity In The Usda And Cip-Fao International Nursery Collections Of Quinoa (Chenopodium Quinoa Willd.) Using Microsatellite Markers, S. A. Christensen, D. B. Pratt, C. Pratt, P. T. Nelson, M. R. Stevens, Eric N. Jellen, Craig E. Coleman, Daniel J. Fairbanks, A. Bonifacio, Michael J. Maughan

Faculty Publications

Quinoa (Chenopodium quinoa Willd.) is a staple food crop for millions of impoverished rural inhabitants of Andean South America where it has been cultivated for millennia. Interest in quinoa, due largely to its superior nutritional characteristics, is fuelling a growing export market and has led to an increased focus on genetic research and the development of quinoa breeding programmes throughout South America. The success of these breeding programmes will rely heavily on the development of core germplasm collections and germplasm conservation. We report the development of a set of fluorescence-tagged microsatellite molecular markers that can be used to characterize genetic …

Threats From The Global Commons: Problems Of Jurisdiction And Enforcement, Stuart Kaye

International Law Studies

No abstract provided.

Earmstrong, Armstrong Atlantic State University

Armstrong News & Publications: e-Armstrong Newsletter (Archived)

No abstract provided.

Ltc Newsletter, University Of Dayton. Ryan C. Harris Learning Teaching Center

LTC Newsletter

Fall 2007

Kinematic Analysis Of Treadmill Walking In Normal And Contused Mice Using The Treadscan System., Jason Beare 1980-

Electronic Theses and Dissertations

Activity-based rehabilitation is important for clinically treating spinal cord injury (SCI). Advances in SCI research are dependent on quality animal models, which rely on our ability to detect functional differences in animals following injury. The purpose of this study is to analyze the gait of normal and contusion-injured mice using the TreadScan® system. TreadScan® utilizes a transparent treadmill belt and a high-speed camera to capture the footprints of animals and automatically analyze gait characteristics. Adult female C57B1/6 mice were gentled and introduced to the treadmill. Animals received either a standardized mild or moderate contusion injury or a sham injury. TreadScan® …

Ridge Preservation Comparing A Flap Vs. A Flapless Technique Using A Demineralized Bone Matrix Allograft Plus Mineralized Particulate Allograft And Covered With A Calcium Sulfate Barrier., Trever L. Siu

Electronic Theses and Dissertations

Aims . The primary aim of this study is to compare the clinical and histologic results of a flap vs. a flapless technique of ridge preservation after 4 months of healing. Both groups received an intrasocket graft of demineralized bone matrix mixed with mineralized particulate allograft that was covered with a calcium sulfate barrier. Methods . Twelve test patients received ridge preservation using the flapless technique while 12 positive control patients were treated with a flap technique. All sockets were grafted with a mixture of demineralized bone matrix and a mineralized particulate allograft. Following tooth extraction horizontal ridge dimensions were …

Validation Of A Short Tandem Repeat Multiplex Typing System For Genetic Individualization Of Domestic Cat Samples, Nikia Coomber, Victor A. David, Stephen J. O'Brien, Marilyn Menotti-Raymond

Biology Faculty Articles

Aim To conduct developmental validation studies on a polymerase chain reaction (PCR) based short tandem repeat (STR) multiplex typing system, developed for the purpose of genetic individualization and parentage testing in domestic cat samples.

Methods To evaluate reproducibility of the typing system, the multiplex was amplified using DNA extracted from hair, blood, and buccal samples obtained from the same individual (n = 13). Additional studies were performed to evaluate the system’s species’ specificity, using 26 North American mammalian species and two prokaryotes Sacchromyces and Escherichia coli, sensitivity, and ability to identify DNA mixtures. Patterns of Mendelian inheritance and mutation …

Venom Expenditure By Viperid And Elapid Snakes: Mechanisms, Adaptation, And Application, Shelton Scott Herbert

Loma Linda University Electronic Theses, Dissertations & Projects

In this dissertation, I examined some of the factors that influence venom expenditure by viperid and elapid snakes in both predatory and defensive contexts. I also considered the consequences of venom delivery into human snakebite victims. In the first of four experiments, In the first experiment, I explored whether the Black-necked Spitting Cobra (Naja nigricollis) metered venom by differential venom gland contraction. Differences in duration of venom flow and venom expended confirmed that this species ejects markedly greater quantities of venom during biting than spitting by varying the duration of venom gland contraction. In the second experiment, I studied the …

Effects Of Distress On Health Care Utilization In Cancer Survivors (Nhis 2004), Natalie Christine Kaiser

Loma Linda University Electronic Theses, Dissertations & Projects

Distress rates have been found to be around 43%, as indicated by a study of five comprehensive cancer centers and as measured by the Distress Thermometer (Jacobsen, et ah, 2005). Furthermore, few studies have examined the current health care utilization among cancer patients as predicted by distress. Thus, population-based data from the NHIS (2004) was analyzed using SUDAAN software 1) to ascertain the current levels of distress as measured by the Kessler 6 scale experienced by cancer survivors based upon demographic characteristics, family structure, physical comorbitities, and cancer-related variables, and 2) to determine whether distress rates reported among cancer survivors …

Physiological Effects Of Vibration In Select Populations, Colleen S. Maloney-Hinds

Loma Linda University Electronic Theses, Dissertations & Projects

Recently, researchers have demonstrated that Whole Body Vibration results in significant increases in skin blood flow. No study has determined if there is an optimal frequency or duration for optimizing this response. In addition, there is no known mechanism for the increase in skin blood flow. It is hypothesized that nitric oxide (NO) is responsible for the increase in skin blood flow due to its ability to vasodilate the smooth muscle in response to shear stress. Therefore, the purpose of this research was to determine the optimal frequency and duration of vibration and determine if NO is the mechanism for …

Predictors Of Emotional Reactions In Women Treated For Breast Cancer, Erin E. Ramirez

Loma Linda University Electronic Theses, Dissertations & Projects

Breast cancer can be a devastating disease that impacts a woman in all spheres of her life (Ingram, 1989). Previous studies have examined the impact of breast cancer on body satisfaction, as well as the impact on emotional well-being. Studies have also examined the role of the coping style that a woman engages in response to the diagnosis and treatment of breast cancer in the woman's psychological adjustment to the disease. However, to date, no research has introduced and tested a multifaceted model.

The purpose of this study was to develop a model predicting psychological maladjustment in women treated for …

A Model For Preventing Anorexia In College Students, Laura Ann Negin

Loma Linda University Electronic Theses, Dissertations & Projects

The prevalence of anorexia nervosa in the general population is relatively low, but anorexia is at the forefront of health concerns because of its seriousness. Unhealthy weight loss has numerous physical, psychological, and social consequences. Most seriously, the mortality rate for people with eating disorders is the highest of all the major psychiatric disorders.

This dissertation presents a model for preventing anorexia nervosa in a population of college students that includes a comprehensive institutional approach, psychoeducational software, a high-risk population, a holistic approach that identifies an individual’s personal risk factors and protective factors, and individual therapy.

The model is built …

Detection Of Simulated Apical Root Resorption Using Three Cone Beam Ct Machines, Marcus Paulson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine orthodontists' ability to discriminate small differences of simulated apical root resorption (SARR) on extracted teeth, using the output from three cone beam computed tomography (CBCT) machines. Twenty-four unrestored maxillary anterior teeth exhibiting normal morphology, were collected. The teeth were scanned by three CBCT machines: 1) the NewTom 3G (AFP imaging, USA), 2) the iCAT (Imaging Sciences, USA) 3) and the MicroCAT II (Siemens Medical, USA). Using a sandblaster the apical portion of each tooth was reduced in 0.5 mm increments up to a total reduction of 1.5 mm. Each root modification was …

Behavioral Compliance And Verbal Intelligence In Children, Jared Jackson

Loma Linda University Electronic Theses, Dissertations & Projects

Compliance with parental requests is an important developmental task necessary in the socialization of children. The majority of research has focused on the relationship between child compliance and variables related to age, parental interactions, and child temperament. While these variables account for almost half of the variance related to compliance in children, there is still a large amount of variance unaccounted for. An area that has not been fully explored is the role of verbal intelligence in behavioral compliance of children. This study explored the contributions that verbal intelligence may play in the behavioral compliance of children. Results from this …

Predictors Of Emotional Reactions In Women Treated For Breast Cancer, Erin E. Ramirez

Loma Linda University Electronic Theses, Dissertations & Projects

Breast cancer can be a devastating disease that impacts a woman in all spheres of her life (Ingram, 1989). Previous studies have examined the impact of breast cancer on body satisfaction, as well as the impact on emotional well-being. Studies have also examined the role of the coping style that a woman engages in response to the diagnosis and treatment of breast cancer in the woman's psychological adjustment to the disease. However, to date, no research has introduced and tested a multifaceted model.

The purpose of this study was to develop a model predicting psychological maladjustment in women treated for …

Predictors Of Female Sexual Dysfunction, Julie M. Merrell

Loma Linda University Electronic Theses, Dissertations & Projects

Tiefer, Hall, and Tavris (2002) described factors comprising four categories of female sexual dysfunction. They suggested that unique factors need to be examined to understand sexual dysfunction in women. Socio-cultural, political, or economic factors, partner and relationship factors, psychological factors, and medical factors described as aspects of women’s lives that can be the source of sexual dysfunction. The current study examined indicators of the above factors-body shame, relationship satisfaction, sexual self-schema, positive and negative affect, and overall health-as predictors of female sexual dysfunction. The hypotheses were: Body shame and negative affect will be negatively associated with sexual function; and relationship …

Posttraumatic And Parent Stress In Parents Of Infant Heart Transplant Recipients, Jessie Rose Stevens

Loma Linda University Electronic Theses, Dissertations & Projects

Heart transplantation during infancy is a life-threatening event, and when successful, the treatment is a life-long process and the potential for life-threatening consequences never ceases. As a result, parents can be impacted in many ways by this traumatic and demanding experience that begins with the initial diagnosis of their infant and continues into the long-term life course of these children. This life-long process has the potential to cause symptoms of posttraumatic stress disorder as well as elevated levels of stress in parents. This study examined parental self-reported post-traumatic stress symptoms and parental stress in parents of children who received a …