Digital Commons Network^™

Sheeppox Virus Kelch-Like Gene Sppv-019 Affects Virus Virulence, C. A. Balinsky, Gustavo A. Delhon, C. L. Afonso, G. R. Risatti, M. V. Borca, R. A. French, E. R. Tulman, S. J. Geary, D. L. Rock

Nebraska Center for Virology: Faculty Publications

Sheeppox virus (SPPV), a member of the Capripoxvirus genus of the Poxviridae, is the etiologic agent of a significant disease of sheep in the developing world. Genomic analysis of pathogenic and vaccine capripoxviruses identified genes with potential roles in virulence and host range, including three genes with similarity to kelch-like genes of other poxviruses and eukaryotes. Here, a mutant SPPV with a deletion in the SPPV-019 kelch-like gene, ΔKLP, was derived from the pathogenic strain SPPV-SA. ΔKLP exhibited in vitro growth characteristics similar to those of SPPV-SA and revertant virus (RvKLP). ΔKLP-infected cells exhibited a reduction in Ca^{2+ …}

High-Throughput Screening For Fatty Acid Uptake Inhibitors In Humanized Yeast Identifies Atypical Antipsychotic Drugs That Cause Dyslipidemias, Hong Li, Paul N. Black, Aalap Chokshi, Angel Sandoval-Alvarez, Ravi Vatsyayan, Whitney Sealls, Concetta Dirusso

Department of Biochemistry: Faculty Publications

Fatty acids are implicated in the development of dyslipidemias, leading to type 2 diabetes and cardiovascular disease. We used a standardized small compound library to screen humanized yeast to identify compounds that inhibit fatty acid transport protein (FATP)-mediated fatty acid uptake into cells. This screening procedure used live yeast cells expressing human FATP2 to identify small compounds that reduced the import of a fluorescent fatty acid analog, 4,4-difluoro-5-methyl-4-bora-3a,4a-diaza-s-indacene-3-dodecanoic acid (C1-BODIPY-C12). The library used consisted of 2,080 compounds with known biological activities. Of these, ~1.8% reduced cell-associated C1-BODIPY-C12 fluorescence and were selected as potential inhibitors of human FATP2- mediated fatty acid …

New And Emended Descriptions Of Gregarines From Flour Beetles (Tribolium Spp. And Palorus Subdepressus: Coleoptera, Tenebrionidae), John J. Janovy Jr., Jillian Tikka Detwiler, Samana Schwank, Matthew G. Bolek, Alaine Knipes, Gabriel J. Langford

John J. Janovy, Jr. Publications

The following new gregarine taxa are described from larvae of flour beetles (Coleoptera: Tenebrionidae): Awrygregarina billmani, n. gen., n. sp., from Tribolium brevicornis; Gregarina cloptoni, n. sp., from Tribolium freemani; Gregarina confusa, n. sp., from Tribolilum confusum; and Gregarina palori, n. sp., from Palorus subdepressus. In addition, the description of Gregarina minuta Ishii, 1914, from Tribolium castaneum, is emended. Scanning electron micrograph studies of these species’ oocysts reveal differences in surface architecture. The Gregarina species have oocysts with longitudinal ridges, visible with SEM, whereas Awrygregarina billmani oocysts have fine circumferential striations; …

Bats Of Barbuda, Northern Lesser Antilles, Scott C. Pedersen, Peter A. Larsen, Hugh H. Genoways, Matthew Morton, Kevel C. Lindsay, Jerry Cindric

University of Nebraska State Museum: Mammalogy Papers

Five species of bats are known to occur on the Lesser Antillean island of Barbuda—Noctilio leporinus, Monophyllus plethodon, Brachyphylla cavernarum, Tadarida brasiliensis, and Molossus molossus. During the present study, two additional species of bats—Artibeus jamaicensis and Natalus stramineus—were added to the chiropteran fauna of the island. Although the ecological diversity of Barbuda is limited, this bat fauna matches those of islands in the region such as Antigua, Nevis, and St. Kitts. It is proposed that this biodiversity of bats is maintained because of the geology of Barbuda provides ample roosting sites and access to freshwater …

The Protective Effect Of Ethyl Pyruvate On Lung Injury After Burn In Rats., Melih Karabeyoglu, Belma Kocer, Ummuhani Ozel, Fatma O. Atasay, Huseyin Ustun, Mete Dolapci, Isil Karabeyoglu, Omer Cengiz

Saudi Medical Journal

OBJECTIVES: To investigate the effects of administered ethyl pyruvate (EP), a novel anti-inflammatory agent, on oxidoinflammatory and apoptotic pathways in the lung tissue of rats in a full-thickness burn model. METHODS: The study took place in Ankara Research and Training Hospital Animal Laboratory, Turkey in June 2006. Thirty-two rats were randomly divided into 4 groups in equal numbers as sham, burn, sham+EP, and burn+EP. The burn model, used produced a full thickness burn of the 30-35% of the total body surface area. Ethyl pyruvate was administered as 40 mg/kg intraperitoneally. Rats were sacrificed after 24 hours, acute lung injury (ALI) …

Determination Of Human Papillomavirus Type 16 Genotype And Construction Of Cloning Vector Ptz57r Encoding Hpv16 E7 Gene., Zahra Meshkat, Hoorieh Soleimanjahi, Mahmoud Mahmoudi, Hessam Mirshahabi, Zuhair M. Hassan, Saeed R. Ghaffari, Tayebeh Sabokbar

Saudi Medical Journal

OBJECTIVES: To isolate and construct a cloning vector containing the human papillomavirus (HPV)16-E7 gene as a target for application as a DNA vaccine. METHODS: The study was performed in 2005 in Iran. The E7 gene, one of the most important HPV oncoproteins and a target molecule for therapeutic vaccines, was amplified by polymerase chain reaction (PCR). The PCR product was cloned into a suitable cloning vector and confirmed by colony-PCR, restriction enzyme analysis, and sequenced. RESULTS: The desired plasmid was sequenced and indicated 99% homology with those mentioned in the Genbank. CONCLUSIONS: The Iranian HPV16 E7 gene sequence is very …

Variations In Serratia Marcescens Differentiation Using Different Primers., Hassan Mohabatkar, Anahita Hamidi, Reza Mohammadzadegan

Saudi Medical Journal

OBJECTIVES: To study primer sequences (1060, 1247, 1254, 1281, 1283, and 1290) for random amplified polymorphic DNA polymerase chain reaction (RAPD-PCR). METHODS: Twenty-four clinical Serratia marcescens (S. marcescens) isolates were obtained over a 6-month period from April 2002 to September 2002 from hospitals in the Fars province of Iran. Six primers were used due to S. marcescens genome properties, and RAPD-PCR was carried out. The results were subjected to unweighted pair-group method analysis using NTSYSpc 2.02. The primers were blasted with the S. marcescens genome, and the primers efficiency was estimated. RESULTS: The results of blast primers with S. marcescens …

Isotretinoin In Acne Agminata., Maryam Daneshpazhooh, Amirhoushang Ehsani, Siavash Toosi, Reza M. Robati

Saudi Medical Journal

Acne agminata is an asymptomatic papulopustular eruption. This condition typically occurs in young adults. The eruption generally runs a self-limited course, but disfiguring scars can occur. Histological examination shows scattered dermal granulomas composed of epitheloid and some giant cells with central caseation. A variety of agents such as wide-spectrum antibiotics, oral steroids, dapsone, and clofazimine have been used with varying degrees of success. Herein, we report 2 Caucasian males with acne agminata, successfully treated with isotretinoin.

Does Interference Competition With Wolves Limit The Distribution And Abundance Of Coyotes?, Kim Murray Berger, Eric M. Gese

United States Department of Agriculture Wildlife Services: Staff Publications

1. Interference competition with wolves Canis lupus is hypothesized to limit the distribution and abundance of coyotes Canis latrans, and the extirpation of wolves is often invoked to explain the expansion in coyote range throughout much of North America.

2. We used spatial, seasonal and temporal heterogeneity in wolf distribution and abundance to test the hypothesis that interference competition with wolves limits the distribution and abundance of coyotes. From August 2001 to August 2004, we gathered data on cause-specific mortality and survival rates of coyotes captured at wolf-free and wolf-abundant sites in Grand Teton National Park (GTNP), Wyoming, USA, …

The Evolutionary Origins Of Human Patience: Temporal Preferences In Chimpanzees, Bonobos, And Human Adults, Alexandra G. Rosati, Jeffrey R. Stevens, Brian Hare, Marc D. Hauser

Department of Psychology: Faculty Publications

To make adaptive choices, individuals must sometimes exhibit patience, forgoing immediate benefits to acquire more valuable future rewards [1–3]. Although humans account for future consequences when making temporal decisions [4], many animal species wait only a few seconds for delayed benefits [5– 10]. Current research thus suggests a phylogenetic gap between patient humans and impulsive, present-oriented animals [9, 11], a distinction with implications for our understanding of economic decision making [12] and the origins of human cooperation [13]. On the basis of a series of experimental results, we reject this conclusion. First, bonobos (Pan paniscus) and chimpanzees ( …

Emended Description And Redetermination Of Sarwaria Caballeroi N. Comb. (Nematoda: Ostertagiinae) With Details Of The Synlophe And Esophageal Characters, Eric P. Hoberg, Arthur Abrams

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Among genera of the ostertagiine nematodes, structural attributes of Spiculopteragia caballeroi are consistent with criteria that diagnose the genus Sarwaria. Specifically, the following characters are compatible with referral to this genus: (1) species characterized by monomorphic males; (2) tapering lateral synlophe in the cervical zone; (3) minuscule, thornlike cervical papillae; (4) length of Ray "4" < Ray "5"; (5) relatively thick or robust Ray "4;" (6) a substantially reduced dorsal lobe and dorsal ray that are disposed or curved ventrally relative to Rays "8"; and (7) a broad, laterally inflated dorsal lobe. Consequently, we propose Sarwaria caballeroi n. comb., and we provide further validation for the genus Sarwaria. Additionally, we propose that the ostertagiines are represented by 12 valid genera, including those characterized by a bursal formula of 2-2-1 (Cervicaprastrongylus, Hyostrongylus, Mazamastrongylus, Spiculopteragia, …

Geographic And Host Range Of The Nematode Soboliphyme Baturini Across Beringia, Anson V.A. Koehler, Eric P. Hoberg, Nikolai E. Dokuchaev, Joseph A. Cook

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The nematode Soboliphyme baturini Petrov, 1930, was found to represent a single species with a relatively broad geographic range across Beringia and northwestern North America on the basis of the assessment of molecular sequence data for adult and juvenile parasites. Refuted are hypotheses suggesting that several cryptic species could be partitioned either among an array of mustelid definitive hosts or across the vast region that links North America and Eurasia. Host specificity for this species is examined on the basis of a comprehensive list for definitive hosts, derived from new field surveys and existing literature for S. baturini. Only …

Effect Of Climatic Warming On The Pacific Walrus, And Potential Modification Of Its Helminth Fauna [Critical Comment], Robert L. Rausch, John C, George, Harry K. Brower

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The decreasing extent of sea-ice in the arctic basin as a consequence of climatic warming is modifying the behavior and diets of pagophilic pinnipeds, including the Pacific walrus, Odobenus rosmarus divergens Illiger, the species emphasized here. Mammals such as the walrus and bearded seal, Erignathus barbatus (Erxleben), cannot remain associated with the sea-ice, and continue to feed on their usual diet of benthic invertebrates inhabiting coastal waters to a depth of approximately 100 m, when the northwestward retreating ice reaches deep waters beyond the margins of the continental shelf. With reduction of their customary substrate (ice), the walrus has become …

Gregarina Niphandrodes (Eugregarinorida: Septatorina): Oocyst Surface Architecture, John J. Janovy Jr., Matthew G. Bolek, Jillian Tikka Detwiler, Samana Schwank, Alaine Knipes, Gabriel J. Langford

John J. Janovy, Jr. Publications

The surface architecture of oocysts produced by Gregarina niphandrodes (Eugregarinorida) from Tenebrio molitor,/i> adults (Coleoptera: Tenebrionidae) as revealed by scanning electron microscopy is reported. Gametocysts were allowed to dehisce on 15-mm, round cover glasses; the cover glasses with their oocysts chains were then mounted on stubs without further processing, and sputter-coated with 20-nm gold-palladium. Scanning electron microscopy was performed at 10-15 kV with a Hitachi 3000N SEM. Oocysts retained their characteristic shapes as reported in the original species description but showed longitudinal ridges of relatively uniform height, width, and spacing, in separate fields on either side of a central equatorial …

Bioluminescence Imaging For Assessment And Normalization In Transfected Cell Arrays, Angela K. Pannier, Eric A. Ariazi, Abigail D. Bellis, Zain Bengali, V. Craig Jordan, Lonnie D. Shea

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Transfected cell arrays (TCAs) represent a high-throughput technique to correlate gene expression with functional cell responses. Despite advances in TCAs, improvements are needed for the widespread application of this technology. We have developed a TCA that combines a two-plasmid system and dual-bioluminescence imaging to quantitatively normalize for variability in transfection and increase sensitivity. The two-plasmids consist of: (i) normalization plasmid present within each spot, and (ii) functional plasmid that varies between spots, responsible for the functional endpoint of the array. Bioluminescence imaging of dual-luciferase reporters (renilla, firefly luciferase) provides sensitive and quantitative detection of cellular response, with minimal post-transfection processing. …

Achieving Millennium Development Goals For Health: Building Understanding, Trust And Capacity To Respond, Timothy Downs, Heidi Jane Larson

Sustainability and Social Justice

Biomedical interventions promise achievement of health-related Millennium Development Goals provided social-, capacity- and knowledge-based constraints to scaling up and reaching marginalized people at risk, are addressed, and balance between prevention and treatment is struck. We argue for a new approach: multi-stakeholder capacity building and learning for empowerment: MuSCLE. MuSCLE is used as a way to frame three systemic weaknesses in traditional health science and policy approaches: (1) a lack of engagement with people at risk to build a collective understanding of the contexts of health problems, including social drivers; (2) a lack of multi-criteria evaluation of alternative interventions; (3) a …

The Legacy Of Joan Vollmer: The Short Significant Life Of A Beat Woman, Christopher Carmona

Theses and Dissertations - UTB/UTPA

In this thesis, I have endeavored to flesh out the life of Joan Vollmer. Joan Vollmer was an essential figure in the Beat Generation of Writers even though she never published a word. Through researching the life of Joan Vollmer, the role that she played in the creation of the Beat Generation becomes clear. Joan Vollmer is mentioned in the major Beat texts, but there is no definitive look at her life and importance. Therefore, I set out to do what no one has done and write about Joan Vollmer' s life. I have collected as many letters that still …

Approximate Entropy Detects The Effect Of A Secondary Cognitive Task On Postural Control In Healthy Young Adults: A Methodological Report, James T. Cavanaugh, Vicki S. Mercer, Nikolaos Stergiou

Journal Articles

Background: Biomechanical measures of postural stability, while generally useful in neuroscience and physical rehabilitation research, may be limited in their ability to detect more subtle influences of attention on postural control. Approximate entropy (ApEn), a regularity statistic from nonlinear dynamics, recently has demonstrated relatively good measurement precision and shown promise for detecting subtle change in postural control after cerebral concussion. Our purpose was to further explore the responsiveness of ApEn by using it to evaluate the immediate, short-term effect of secondary cognitive task performance on postural control in healthy, young adults.

Methods: Thirty healthy, young adults performed a modified version …

Lsu Health Sciences Center New Orleans Update, Larry H. Hollier Md

LSUHSC Hurricane Katrina Archive: Reports & Presentations

"LSU Health Sciences Center New Orleans Update" is a PowerPoint presentation of 52 slides presented by Larry H. Hollier, MD, FACS (Dean of the School of Medicine 2004-2007, Chancellor 2006-2021) to the LSUHSC Board of Supervisors in October 2007.

This presentation includes academic program updates, facilities updates, student enrollment numbers, and faculty recruitment details two years after Hurricane Katrina forced the temporary closure and relocation of LSU Health Sciences Center - New Orleans.

Lsuhsc Facilities Daily Update: October 2007, Lsuhsc Property And Facilities Management

LSUHSC Facilities Daily Updates: 2007

LSUHSC Facilities Daily Updates from October 2007.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Lsuhsc Facilities Biweekly Update: October 2007, Lsuhsc Property And Facilities Management

LSUHSC Facilities Biweekly Updates: 2007

LSUHSC Facilities Biweekly Updates from October 12 and 26, 2006.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Role Of Actin Cytoskeletal Dynamics In Activation Of The Cyclic Amp Pathway And Hwp1 Gene Expression In Candida Albicans, Michael J. Wolyniak, Paula Sundstrom

Dartmouth Scholarship

Changes in gene expression during reversible bud-hypha transitions of the opportunistic fungal pathogen Candida albicans permit adaptation to environmental conditions that are critical for proliferation in host tissues. Our previous work has shown that the hypha-specific adhesin gene HWP1 is up-regulated by the cyclic AMP (cAMP) signaling pathway. However, little is known about the potential influences of determinants of cell morphology on HWP1 gene expression. We found that blocking hypha formation with cytochalasin A, which destabilizes actin filaments, and with latrunculin A, which sequesters actin monomers, led to a loss of HWP1 gene expression. In contrast, high levels of HWP1 …

Nova Quarterly: The University Of Texas At El Paso, The University Of Texas At El Paso University Communications

NOVA

Miner Fever
Homecoming 2007
Fall, 2007. Vol. 45, No.3; No. 171.

Investigating A Method To Measure Sperm Transfer In Chelidonura Sandrana (Opisthobranchia: Cephalaspidea), Kate Kunigelis

Independent Study Project (ISP) Collection

This paper investigates possible methods for measuring sperm transfer in the internal fertilizing, simultaneous hermaphrodite Chelidonura sandrana (Opisthobranchia: Cephalaspidea). Comparing sperm amount transferred in copulations has significance for testing the assumption that sperm transfer is linearly correlated with copulation duration as well as providing a tool for future studies. Various methods of preparing, treating, and viewing sperm samples were attempted. Two unsuccessful pilot studies were conducted to test free sperm counts and measuring sperm pellet surface area. Future research should focus on optimizing centrifugation method for surface area measurements of sperm clusters and resuspending sperm clusters to enable sperm counting. …

The Classic, Fall 2007, Public Relations

The Classic, 2000-2009

President's Report: 125 Years of His Stories; Northwestern names ninth president; Northwestern moves up in rankings; Inbox; Fishing for hope; Enrollment second highest; Student's music video featured at festival; New staff bring intercultural and mission experience; New & improved; Nine join NWC faculty: Dr. Thomas Bogue, Deb Bomgaars, Arnold Carlson, Karissa Carlson '03, Dr. Luke Dahn, Andrea Donahoe, Ann VanderKooi Minnick '88, Michell Van Wyhe, Linda Ver Steeg; Of Course: Hollywood and the Meaning of Life; Photo essay: What a RUSH!; Face Value: Roger Ewoldt; Bible Study; Murphy's Laws for Leading; A Timeline of Northwestern College History; 125 Years in …

Religious V. Secular Ideologies And Sex Education: A Response To Professors Cahn And Carbone, Vivian E. Hamilton

Faculty Publications

No abstract provided.

Arbuscular Mycorrhizal Fungal Root Colonization And Inoculum Propagules In Deciduos Floodplain Forests Of Southwestern Michigan, Usa, Peter G. Avis, Sara D. Foster, Paul D. Olexia

Faculty and Professional Research

We examined the arbuscular mycorrhizal (AM) fungi of temperate deciduous floodplain forests in southwest Michigan, USA, and the relationship between soil moisture and AM fungal root colonization and inoculum. In four floodplain forests, AM root colonization was measured for roots collected from soil samples taken along soil moisture, micro-topography and vegetation gradients. An AM fungal inoculum bioassay was also conducted using these samples to measure the amount of infective propagules found across these gradients. Although soil moisture had no significant effect on either AM parameter measured, the effect of forest site was significant in most instances. We also found a …

Jefferson Alumni Bulletin – Volume 56, Number 4, Fall 2007

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 56, Number 4, Fall 2007

Dean’s Column: My Story; Page 2

Findings: Gene Therapy Used to Reverse Heart Failure in Animals, Colon Cancer: A Hormone Deficiency Disease, Breast Cancers More Aggressive in African Americans; Page 5

On Campus; Page 8

A Dedication to the Future of Clinical Care; Page 11

Class Notes; Page 26

In Memoriam; Page 30

Alumni Weekend; Page 32

Alumni Giving; Page 34

The Bulletin Celebrates 85 Years; Page 48

By the Numbers: Eighty Five…

2007 October, Office Of Communications & Marketing, Morehead State University.

Morehead State Press Release Archive, 1961 to the Present

Press releases for October of 2007.

Mechanisms Of Fatigue Differ After Low- And High-Force Fatiguing Contractions In Men And Women, Tejin Yoon, Bonnie A. Schlinder-Delap, Erin E. Griffith, Sandra K. Hunter

Exercise Science Faculty Research and Publications

The magnitude of failure in voluntary drive after fatiguing contractions of different intensities in men and women is not known. The purpose of this study was to compare the time to task failure and voluntary activation of men and women for a sustained isometric contraction performed at a low and high intensity with the elbow flexor muscles. Nine men and nine women sustained an isometric contraction at 20% and 80% of maximal voluntary contraction (MVC) force until task failure during separate sessions. The men had a shorter time to failure than women for the 20% but not the 80% MVC …