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Paediatricians' Liability To Patients' Parents For Negligent Genetic Testing, Anthony Sangiuliano Jul 2026

Paediatricians' Liability To Patients' Parents For Negligent Genetic Testing, Anthony Sangiuliano

Osgoode Hall Law Journal

The Ontario Superior Court of Justice has recently held that a paediatrician might owe a duty of care to a patient’s parents when performing genetic testing on the patient and communicating test results to the parents. The parents may be able to claim damages against the paediatrician for breach of this duty if, in reliance on a miscommunication about the test results, they conceive a subsequent child who is later born with a disability. I call the tort alleged by the parents in these circumstances a subspecies of “paediatric triangular torts.” In this article, I demonstrate the conceptual feasibility of …


Social Psychology, Justin Storbeck, Justin Storbeck Jul 2026

Social Psychology, Justin Storbeck, Justin Storbeck

Open Educational Resources

The document is a syllabus for a Social Psychology course. The course is designed as an introductory course to Social Psychology. The course consist of OER materials and designed to place no financial burden on the student. The major topics of social psychology will be covered using an OER textbook accompanied by lecture materials, assignments, videos, and learning objectives.


Climate Change And Desert Ecosystem Resilience: A Systematic Review Of Impacts, Adaptation Strategies, And Sustainability Pathways, Ghada Abd Elsattar Mohammed Oraby, Garmat Zahra Jul 2026

Climate Change And Desert Ecosystem Resilience: A Systematic Review Of Impacts, Adaptation Strategies, And Sustainability Pathways, Ghada Abd Elsattar Mohammed Oraby, Garmat Zahra

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Desert ecosystems are among the most climate-sensitive environments on Earth, where rising temperatures, altered precipitation regimes, and increasing aridity threaten ecosystem stability, biodiversity, and ecological functioning. Despite covering more than one-third of the global land surface, a comprehensive understanding of how climate change affects desert ecosystem resilience and the effectiveness of adaptation strategies remains limited. This study conducted a systematic review following the PRISMA framework to evaluate the impacts of climate change on desert ecosystem resilience and to identify effective adaptation and restoration pathways. A total of 16 high-quality studies were selected from 403 records retrieved from the Scopus database. …


Evaluation Of Tsunami Preparedness And Appraisal Of Disaster Mitigation Education In Kebumen Regency, Indonesia: An Application Of Marker-Based Augmented Reality Approach, Muhammad Guruh Bintang Wicaksana, Erni Suharini, Andi Irwan Benardi, Edi Kurniawan, Puji Lestari, Atta-Ur Rahman Jul 2026

Evaluation Of Tsunami Preparedness And Appraisal Of Disaster Mitigation Education In Kebumen Regency, Indonesia: An Application Of Marker-Based Augmented Reality Approach, Muhammad Guruh Bintang Wicaksana, Erni Suharini, Andi Irwan Benardi, Edi Kurniawan, Puji Lestari, Atta-Ur Rahman

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

This study addresses the critical gap in tsunami disaster mitigation education and the lack of interactive, contextually field-based disaster education media. It develops and evaluates a tsunami preparedness medium using a Marker-Based Augmented Reality (MBAR) approach, specifically tailored to the tsunami risk profile of Karangbolong Village, Kebumen Regency, Indonesia. Methodologically, the study integrates three frameworks: a disaster literacy model (knowledge, skills, attitudes), a disaster literacy continuum (basic to critical), and the UNESCO-IOC Tsunami Ready 12-indicator framework, combining them into a single instructional product developed through the Multimedia Development Life Cycle (MDLC). This integration of all three frameworks into one locally …


Completing The Hospital Transfer Journey: A Descriptive Study Of The Demographic, Clinical, And Facility Factors Associated With Successful Transfer Back​, Chelsy Chairez-Ortiz, Natalie Crump Jul 2026

Completing The Hospital Transfer Journey: A Descriptive Study Of The Demographic, Clinical, And Facility Factors Associated With Successful Transfer Back​, Chelsy Chairez-Ortiz, Natalie Crump

Posters: 2026 Summer Undergraduate Research Program

No abstract provided.


Teaching Old Statutes New Tricks: Towards Equitable Participation In Transportation Act Section 4(F) And Nhpa Section 106, Laura Mott Jul 2026

Teaching Old Statutes New Tricks: Towards Equitable Participation In Transportation Act Section 4(F) And Nhpa Section 106, Laura Mott

Villanova Environmental Law Journal (1991 - )

No abstract provided.


Perbandingan Kesenjangan Perilaku Manusia Purba Di Wilayah Sulawesi Dan Flores, Kaylica Putri Kurniawan, Siti Oktavia Caroline, Nazwa Fariha Ramadhani Jul 2026

Perbandingan Kesenjangan Perilaku Manusia Purba Di Wilayah Sulawesi Dan Flores, Kaylica Putri Kurniawan, Siti Oktavia Caroline, Nazwa Fariha Ramadhani

Multikultura

Wallacea, particularly the islands of Sulawesi and Flores, holds important archaeological evidence of the behavioral transition between Homo sapiens and earlier archaic hominins. This article aims to compare the behavioral gaps that occurred at two sites, namely Leang Bulu Bettue, Sulawesi, and Liang Bua, Flores. The results of the study indicate that Sulawesi and Flores have significantly different gap patterns, where at Leang Bulu Bettue there was a drastic change in substance, while at Liang Bua the opposite behavior occurred, where there was technological continuity from Homo floresiensis to early Homo sapiens with gradual behavioral changes. The results of this …


Transformasi Jeong Dalam Budaya Korea: Representasi Keluarga Pilihan Dalam Film Korea Love In The Big City, Widad Marshallova Nursandi, Fadhila Hasby Jul 2026

Transformasi Jeong Dalam Budaya Korea: Representasi Keluarga Pilihan Dalam Film Korea Love In The Big City, Widad Marshallova Nursandi, Fadhila Hasby

Multikultura

Jeong is an important cultural value in South Korean society that has traditionally been associated with family relationships, emotional closeness, and a sense of togetherness. Social changes in contemporary Korean society have created space for jeong to develop beyond biological family ties. This study aims to analyze the transformation of the meaning of jeong through the representation of chosen family in the film Love in the Big City (LitBC), which is represented as a form of negotiation with dominant family norms. This research employs a qualitative approach using cultural text analysis based on Stuart Hall's theory of representation. The data …


Reproduksi Pola Keibuan Tokoh Zhenya Dalam Film Нелюбовь (Nelyubov) ‘Tanpa Cinta’ (2017) Karya Andrey Zvyagintsev, Ratu Diva Majirelle, Thera Widyastuti Jul 2026

Reproduksi Pola Keibuan Tokoh Zhenya Dalam Film Нелюбовь (Nelyubov) ‘Tanpa Cinta’ (2017) Karya Andrey Zvyagintsev, Ratu Diva Majirelle, Thera Widyastuti

Multikultura

Andrey Zvyagintsev’s Нелюбовь (Nelyubov) or Loveless (2017) portrays the absence of affection in a family through divorce, child neglect, and emotional disconnection. This study analyzes the reproduction of Zhenya’s mothering pattern through Nancy Chodorow’s feminist psychoanalysis. Zhenya is read in three positions: a daughter lacking maternal affection, a wife in a fractured marriage, and a mother emotionally distant from Alyosha. Using qualitative content analysis, this study examines scenes, dialogues, expressions, gestures, character relations, and visual elements. The findings show that Zhenya’s mothering pattern is reproduced through childhood affective deprivation, an unsupportive marriage, social expectations of motherhood, and maternal …


Pemaknaan Ikon Makhluk Hidup Dengan Kaligrafi Arab Pada Srabad Dari Kesultanan Cirebon, Fitria Anisya, R. Cecep Permana Jul 2026

Pemaknaan Ikon Makhluk Hidup Dengan Kaligrafi Arab Pada Srabad Dari Kesultanan Cirebon, Fitria Anisya, R. Cecep Permana

Multikultura

Islamic art in the Nusantara (Indonesian Archipelago) represents a fusion of Islamic tradition and local cultural wisdom that flourished through coastal trade routes. One of the most distinctive manifestations of this fusion is the art of srabad Cirebon. Etymologically, the term srabad derives from the Javanese expression "mingser saking abad", meaning the transition from the Hindu era to the Islamic era. This art form presents anthropomorphic elements uncommon in conventional Islamic artistic tradition, in which icons of living creatures are specifically constructed from the structure of Qur'anic verses. Studies that examine the relationship between the depiction of living creature icons …


Tinjauan Arkeologis Dan Interaksi Manusia Toalean Di Leang Panninge, Kabupaten Maros, Sulawesi Selatan, Naila Maulidiya Ajitoko, Mayfa Rahmah Padmarani, Syakira Athiyah As'ad Jul 2026

Tinjauan Arkeologis Dan Interaksi Manusia Toalean Di Leang Panninge, Kabupaten Maros, Sulawesi Selatan, Naila Maulidiya Ajitoko, Mayfa Rahmah Padmarani, Syakira Athiyah As'ad

Multikultura

The karst landscape of South Sulawesi served as the habitat of Toalean culture bearers, a Middle Holocene hunter-gatherer group active from 8,000 to 1,500 years ago, recognized through distinctive artefacts including Maros points, backed microliths, and osseous tools. This paper conducts an archaeological review of Toalean remains at Leang Panninge, Maros Regency, covering material culture, site stratigraphy and chronology, and population interactions within the Wallacean migration context, using a descriptive-analytical literature review approach. Findings reveal well-preserved Toalean cultural deposits spanning 9,400 to 1,500 years ago. The most significant discovery is the skeletal remains of a female individual aged 17–18 years, …


Situs Lida Ajer Dalam Konteks Supererupsi Erupsi Toba, Zulianikha S. Putri, Arni Nazirawati, Alia Fatima Jul 2026

Situs Lida Ajer Dalam Konteks Supererupsi Erupsi Toba, Zulianikha S. Putri, Arni Nazirawati, Alia Fatima

Multikultura

The Toba eruption approximately 74,000 years ago was one of the largest volcanic events of the Quaternary and is often associated with the catastrophic hypothesis, which argues that the event caused extreme global cooling and severe reductions in human populations. However, recent studies suggest that its impacts were less destructive than previously assumed. This paper examines the position of Lida Ajer Cave within the context of the Toba eruption through a literature review of archaeological, geological, and paleoenvironmental publications. The review shows that the presence of Homo sapiens at Lida Ajer, dated to approximately 73,000–63,000 years ago, places the site …


Kajian Paleoantropologi Homo Floresiensis Di Liang Bua Dan Mata Menge Tahun 2016-2026, Candra Agustin, Sahla Nabillah, Siti Zahra Indah Permata Jul 2026

Kajian Paleoantropologi Homo Floresiensis Di Liang Bua Dan Mata Menge Tahun 2016-2026, Candra Agustin, Sahla Nabillah, Siti Zahra Indah Permata

Multikultura

The discovery of Homo floresiensis at Liang Bua Cave, Flores Island, in 2003 stands as one of the most revolutionary breakthroughs in twenty-first-century paleoanthropology. This small-bodied hominin species sparked global scientific debate regarding both its species validity and the possibility of pathological conditions in the discovered individual. This study aims to analyze the development of paleoanthropological interpretations of Homo floresiensis at the Liang Bua and Mata Menge sites during the period 2016–2026. A qualitative method with a descriptive-analytical literature review approach was applied to relevant international scientific publications. The results show that redating of the Liang Bua site revised the …


Penggunaan Onomatope Dalam Buku Cerita Anak Berbahasa Mandarin Dan Bahasa Indonesia: Analisis Kontrastif, Ruixi Zou, Usmi Usmi, Uti Aryanti Jul 2026

Penggunaan Onomatope Dalam Buku Cerita Anak Berbahasa Mandarin Dan Bahasa Indonesia: Analisis Kontrastif, Ruixi Zou, Usmi Usmi, Uti Aryanti

Multikultura

This article examines the comparison of onomatopoeia in Mandarin Chinese and Indonesian in children's literature. The study aims to identify, classify, and compare onomatopoeic forms found in the Mandarin children's story Bǎo Húlú De Mìmì (The Secret of the Magic Gourd) and the Indonesian children's story collection Sehari Satu Dongeng. This research employs a descriptive qualitative approach and a contrastive analysis method. The data were collected through close reading and note-taking techniques, and were analyzed using referential and comparative methods. The classification is based on the source of the represented sounds, namely human sounds, animal sounds, natural phenomena, and …


Kuasa Tokoh Perempuan Dalam Cerpen “Sang Pemuja” Karya Laksmi Pamuntjak, Nindita U. Dewanti, Mamlahatun -. Buduroh - Jul 2026

Kuasa Tokoh Perempuan Dalam Cerpen “Sang Pemuja” Karya Laksmi Pamuntjak, Nindita U. Dewanti, Mamlahatun -. Buduroh -

Multikultura

This study examines the forms of power exercised by the main female character in the short story “Sang Pemuja” by Laksmi Pamuntjak using the theory of power feminism. The primary focus of this study is the decisions and actions of the female character that demonstrate power over her body and life choices. This study aims to explain the practices of power feminism carried out by the female character in the short story “Sang Pemuja.” The research data consists of narrative text collected using the note-taking method, to be analyzed based on the principles of power feminism proposed by Naomi Wolf …


Productive Zakāh, Service Quality, And The Welfare Of Zakāh Beneficiary Via Economic Empowerment In Indonesia, Hariya Toni, Muhammad Hisyam Syafii Jul 2026

Productive Zakāh, Service Quality, And The Welfare Of Zakāh Beneficiary Via Economic Empowerment In Indonesia, Hariya Toni, Muhammad Hisyam Syafii

Journal of King Abdulaziz University: Islamic Economics

This study investigates how productive zakāh management and service quality influence the welfare of zakāh beneficiary (mustahik), with economic empowerment positioned as a mediating construct within the zakāh ecosystem of Sungai Penuh City. Using a quantitative explanatory design and SEM‑PLS analysis, the research surveyed mustahik who received productive zakāh through a structured sampling procedure. The findings demonstrate that both effective management of productive zakāh and high‑quality institutional services significantly enhance mustahik’s welfare. Among the examined variables, economic empowerment emerges as the most influential factor, acting as a partial mediator that strengthens the relationship between institutional practices and …


Abstracts Of The 71st Annual Conference Of The Mississippi Association Of Entomologists, Nematologists, And Plant Pathologists (Maenpp) Jul 2026

Abstracts Of The 71st Annual Conference Of The Mississippi Association Of Entomologists, Nematologists, And Plant Pathologists (Maenpp)

Midsouth Entomologist

October 27 & 28, 2025


Exploring The Relations Between Sleep And Mental Health Through The Constructs Of Sleep Health, Psychological Well-Being, Depression, And Anxiety, Taylor G. Wandtke Jul 2026

Exploring The Relations Between Sleep And Mental Health Through The Constructs Of Sleep Health, Psychological Well-Being, Depression, And Anxiety, Taylor G. Wandtke

Undergraduate Honors Theses

Sleep and Mental Health have a variety of definitions and underlying constructs, as well as questionnaires to measure them. This study analyzed sleep and mental health constructs using a variety of questionnaires to examine how they may influence one another, providing valuable insight into the utility of both newly developed and established measures. With an analysis sample of N = 27, this study assessed the reliability of the novel Sleep Health Item Bank (SHIB) across its 14 dimensions and its correlations among psychological well-being, depression, and anxiety scores. Psychological well-being (PWB) was assessed by Ryff’s (1995) 18-item scale, and depression …


Surveys For Rare Springsnails In Southeast Oregon, 2025 With A Focus On The Donner Und Blitzen Pebblesnail (Fluminicola Insolitus), Jesse Laney Jul 2026

Surveys For Rare Springsnails In Southeast Oregon, 2025 With A Focus On The Donner Und Blitzen Pebblesnail (Fluminicola Insolitus), Jesse Laney

Institute for Natural Resources Publications

The Donner und Blitzen pebblesnail (Fluminicola insolitus) is a critically imperiled (G1/S1) freshwater snail historically known from a single spring, Page Springs, in the Donner und Blitzen River drainage of Harney County, Oregon. The species was petitioned for listing under the U.S. Endangered Species Act in February 2024. On January 26, 2026, the U.S. Fish and Wildlife Service published a positive 90-day finding initiating species status review (USFWS 2026).

In August 2025, the Oregon Biodiversity Information Center (ORBIC) at Portland State University, in coordination with the Nevada Division of Natural Heritage (NDNH), the U.S. Fish and Wildlife Service (USFWS), and …


Women’S Experience In Digital Literature As A Form Of Resistance Against Patriarchy, Tazkia Maula Azzari, Mina Elfira Jul 2026

Women’S Experience In Digital Literature As A Form Of Resistance Against Patriarchy, Tazkia Maula Azzari, Mina Elfira

International Review of Humanities Studies

This paper aims to shed light on an emerging type of digital literature on X that acts as a medium for women to express their struggle and feelings in a patriarchal society. This new form of digital literature is novel for it has been popularized on X in the past few years, therefore there is much to explore regarding this field. In particular, this paper will look into how this new form of literature is being used by women to express their resistance against patriarchy on the digital sphere. The qualitative method with a feminist approach was used in this …


Effective Techniques In Equine Assisted Therapies From The Facilitators Perspective, Emily Dolezal Jul 2026

Effective Techniques In Equine Assisted Therapies From The Facilitators Perspective, Emily Dolezal

Walden Dissertations and Doctoral Studies

Equine assisted therapies have been shown to be an effective treatment approach for individuals experiencing mental health issues. However, there have been rising challenges in standardization and nomenclature throughout the field. Current research supporting the benefits of equine assisted therapies is often from the client perspective. There is a gap in understanding what occurred in session that made it beneficial to their mental health. The purpose of this phenomenological study was to describe the lived experiences of equine assisted therapy facilitators in terms of mechanisms that produce positive changes in their clients. The theories and concepts that ground this study …


Intermembrane Coupling Between Bcl-Xl And The Ip3 Receptor Supports Local Ca2+ Transfer At Er-Mitochondrial Contacts, Arijita Ghosh, David Weaver, Chi Li, György Hajnóczky Jul 2026

Intermembrane Coupling Between Bcl-Xl And The Ip3 Receptor Supports Local Ca2+ Transfer At Er-Mitochondrial Contacts, Arijita Ghosh, David Weaver, Chi Li, György Hajnóczky

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Bcl-xL, an anti-apoptotic Bcl-2 family protein, engages laterally with Bak/Bax in the outer mitochondrial membrane (OMM) to inhibit apoptosis and interacts with the IP3 receptor Ca2+ channels (IP3Rs) in the endoplasmic reticulum (ER) membrane to control Ca2+ release. It is unknown if OMM-localized Bcl-xL can also interact in trans with IP3Rs at ER-mitochondrial contacts to form a tethering complex that supports IP3R-mediated local Ca2+ transfer from ER to mitochondria. We establish that IP3R-mitochondria Ca2+ signal propagation depends on Bcl-xL. By targeting Bcl-xL specifically to different subcellular compartments, we find that OMM-localized Bcl-xL increases the efficacy …


Neurint In The Age Of Generative Agentic Ai: A Proposed Paradigm For Left-Of-Bang Strategic Deterrence, James Giordano, Elise Annett Jul 2026

Neurint In The Age Of Generative Agentic Ai: A Proposed Paradigm For Left-Of-Bang Strategic Deterrence, James Giordano, Elise Annett

Strategic Insights

This commentary focuses on how neurocognitive intelligence, or NEURINT, could be operationalized through generative agentic artificial intelligence to strengthen anticipatory intelligence and left-of-bang deterrence. NEURINT combines neuroscience, psychology, behavioral science, computational modeling, and traditional intelligence to better understand the cognitive, emotional, cultural, and organizational factors shaping adversary decision-making. This piece looks at how agentic AI, large-scale data integration, cognitive digital twins, and probabilistic forecasting could help intelligence, surveillance, and reconnaissance identify behavioral patterns, escalation thresholds, vulnerabilities, and potential intervention points before hostile activity becomes operational. It also emphasizes that AI should augment and not replace human analysts. Human judgment, ethical …


Effects Of Montessori-Based Stimulation On Fine And Gross Motor Development Among Children With Stunting: A Quasi-Experimental Study, Indah Rahmadaniah, Tukimin Bin Sansuwito, Rini Anggeriani, Rinda Lamdayani, Ade Marlisa Rahmadayanti, Aris Citra Wisuda Jul 2026

Effects Of Montessori-Based Stimulation On Fine And Gross Motor Development Among Children With Stunting: A Quasi-Experimental Study, Indah Rahmadaniah, Tukimin Bin Sansuwito, Rini Anggeriani, Rinda Lamdayani, Ade Marlisa Rahmadayanti, Aris Citra Wisuda

Jurnal Keperawatan Indonesia

Stunting affects not only physical growth but also several aspects of child development, including gross and fine motor skills. Early stimulation interventions, such as Montessori-based activities, have been proposed to enhance developmental outcomes through structured sensorimotor experiences. This study aimed to evaluate the effects of Montessori-based stimulation on motor development among children with stunting and to compare its outcomes with those of conventional stimulation. A quasi-experimental study with intervention and control groups was conducted among 120 children with stunting aged 36–59 months. Participants were allocated to either a Montessori group (n = 60) or a conventional stimulation group (n = …


Ascc-M Based Transformational Education Model For Enhancing Carbon Literacy And Agroecological Resilience Among Rural Farmers, Alya Dwi Arianty, Fitria Fatichatul Hidayah, Eny Winaryati, Rica Mae Badilla Guarin Jul 2026

Ascc-M Based Transformational Education Model For Enhancing Carbon Literacy And Agroecological Resilience Among Rural Farmers, Alya Dwi Arianty, Fitria Fatichatul Hidayah, Eny Winaryati, Rica Mae Badilla Guarin

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Climate change has become a major ecological and social challenge affecting food security and agricultural sustainability worldwide. The agricultural sector significantly contributes to carbon emissions through fertilizer use and land conversion, particularly in developing countries. This study aims to conceptualize a place-based, technology-enhanced Transformational Education Model grounded in Agro-Smart Carbon Capture Microbiome (ASCC-M) technology, designed to strengthen rural farmers' carbon literacy and agroecological resilience while advancing geography education through deeper understanding of human–environment interactions, spatial agricultural processes, and climate-related dynamics within real rural landscapes. The research employed conceptual design through systematic literature review and model development, integrating theories of transformative …


Loss Of Pleasure (Anhedonia): A Sex-Dependent, Cross-Species Consequence Of Unpredictable Signals To The Perinatal Brain, Anna M. Zhou, Madison R. Tetzlaff, Laura M. Glynn, Curt A. Sandman, Hal S. Stern, Tallie Z. Baram, Elysia Poggi Davis Jul 2026

Loss Of Pleasure (Anhedonia): A Sex-Dependent, Cross-Species Consequence Of Unpredictable Signals To The Perinatal Brain, Anna M. Zhou, Madison R. Tetzlaff, Laura M. Glynn, Curt A. Sandman, Hal S. Stern, Tallie Z. Baram, Elysia Poggi Davis

Psychology Faculty Articles and Research

Reward seeking is an essential component of human behavior. Anhedonia (reduced motivation for and pleasure in reward) is a core feature of several mental illnesses. Early life adversity associates with later impairments in reward behaviors and related psychopathology; however, specific aspects of early adversity that lead to disrupted reward behaviors are unknown. Capitalizing on evidence that unpredictable signals to the developing brain constitute adversity and influence neurodevelopment, we examined whether exposure to perinatal unpredictable maternal signals associated with diminished reward responsivity, and probed causality using experiments in mice. We analyzed a longitudinal human study (N=158 mother/child dyads) and a …


Development Of Perineal Electric Massager Experience (Pem-X) To Improve Perineal Elasticity, Suryani Manurung, Amalia Mely, Yetty Mariani Tambun Jul 2026

Development Of Perineal Electric Massager Experience (Pem-X) To Improve Perineal Elasticity, Suryani Manurung, Amalia Mely, Yetty Mariani Tambun

Jurnal Keperawatan Indonesia

Perineal injury remains a common concern in vaginal childbirth, with a prevalence of 30.6%. Low maternal perineal massage practice is a contributing factor to decreased perineal elasticity and an increased risk of perineal trauma. This pilot study aimed to develop the Perineal Electric Massager Experience (PEM-X) to support mothers in self-guided perineal massage. The research employed a level 4 Research and Development (R&D) method with a one-group pretestposttest design. The study sample consisted of two parts: the PEM-X prototype and postpartum mothers who had vaginal deliveries. A purposive sampling technique was used to recruit 10 postpartum mothers who had vaginal …


Modeling Mrna Delivery And Release By The Charge-Shifting Polymer Pdmaema, Heather L. Weston, Loan Nguyen, Steven Gwaltney Jul 2026

Modeling Mrna Delivery And Release By The Charge-Shifting Polymer Pdmaema, Heather L. Weston, Loan Nguyen, Steven Gwaltney

Research Experiences for Undergraduates in Computational Methods with Applications in Materials Science

Poly(2- (dimethylamino) ethyl) methacrylate (pDMAEMA) is a charge-shifting polymer that can be attached to genetic material like mRNA and that aids delivery into cells. pDMAEMA has been studied in vitro to determine its intercellular interactions, but the intracellular mechanisms are not well understood. However, using computational chemistry methods like molecular dynamics (MD) simulations, we observed intracellular mechanics at an atomic level to understand the delivery and release of mRNA into a cell with pDMAEMA polymers. This was accomplished by completing individual MD simulations of pDMAEMA and mRNA. Initial simulations were completed of pDMAEMA decamers. Following that, the mRNA sequence that …


"It Doesn't Matter Where Ocd Comes From," Or Does It?, Caitlin M Pinciotti, Ryan J Mccarty, Gabriella T Ponzini Jul 2026

"It Doesn't Matter Where Ocd Comes From," Or Does It?, Caitlin M Pinciotti, Ryan J Mccarty, Gabriella T Ponzini

Faculty, Staff and Students Publications

Purpose of review: This review critically evaluates the claim that etiology is not relevant to cognitive behavioral therapy (CBT) for obsessive-compulsive disorder (OCD). Research on the clinical presentation and treatment outcomes associated with traumatic/stressor and biological etiologies is presented.

Recent findings: The extant literature demonstrates varying clinical utility across the reviewed etiologies. Traumatic/stressor etiologies show the most consistent and robust evidence of clinical utility, demonstrating compelling associations with clinical presentation and treatment outcomes, while also being amenable to existing evidence-based approaches. Medical conditions (e.g., Pediatric Acute onset Neuropsychiatric Syndrome) and neurobiological factors also demonstrate considerable associations with OCD presentation, yet …


What Does Sentience Mean At The Neural Level?, Björn Brembs Jul 2026

What Does Sentience Mean At The Neural Level?, Björn Brembs

Animal Sentience

Jonathan Birch's (2025) LSE criteria for sentience include motivational trade-offs, exemplified by C. elegansweighing hunger against desiccation risk. Yet once the neural circuit is known, this "trade-off" reduces to a single inhibitory synapse—an ‘elemental’ account discrediting the ‘molar’ one. My commentary illustrates the same discrepancy in Drosophila: dopaminergic ramping during courtship as it progressively suppresses threat-detecting neurons; so persistence past danger reflects recalibrated valuation rather than a weighed decision. As neurobiology increasingly discovers such discrepancies, all criteria resting on behavioral classifications risk being defined away without altering the behavior's validity.