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The Design And Synthesis Of Novel Chelates For The Precipitation Of Mercury, Aaron Robert Hutchison

University of Kentucky Doctoral Dissertations

Mercury has been an element of great industrial importance since early times.This wide utilization of the element has led to pervasive mercury contamination in theglobal environment. Due to mercury's high toxicity, this is a matter of great concern. Anumber of methods, includ ing phytoremediation, filtration, and precipitation/chelation,have been investigated to remove mercury from the environment. Unfortunately, thesemethods are not entirely satisfactory for the in-situ remediation of mercury from aqueousenvironments.The hypothesis of this dissertation is that this can best be accomplished by theaddition of a large and flexible sulfur-based chelate, that will bind mercury in atetracoordinate and presumably tetrahedral environment, to …

The Effect Of A Nominal Fee On Treatment Choices For Children Needing Dental Rehabilitation, D'Audra M. Cole

Theses and Dissertations

Objective: The purpose of the study was to determine if a co-payment resulted in a differential preference for general anesthesia (GA) or oral sedation (OS) and, if so, to examine whether age, the number of appointments, perceived risks of treatment, child's awareness during treatment, or insurance type appeared to play a role in this preference.Methods: Using a cross-sectional survey design, questionnaires were distributed to caregivers of patients in the waiting room of the Virginia Commonwealth University Pediatric Dental Clinic. Two different questionnaires were distributed randomly. Both surveys described a scenario with the need for dental treatment under general anesthesia (GA) …

The Quantitative Genetics Of Neurodevelopment: A Magnetic Resonance Imaging Study Of Childhood And Adolescence, James Eric Schmitt

Theses and Dissertations

Understanding the causes of individual differences in brain structure may give clues about the etiology of cognition, personality, and psychopathology, and also may identify endophenotypes for molecular genetic studies on brain development. We performed a comprehensive statistical genetic study of anatomic neuroimaging data from a large pediatric sample (N=600+) of twins and family members from the Child Psychiatry Branch at the NIMH. These analyses included variance decomposition of structural volumetric endophenotypes at several levels of resolution, voxel-level analysis of cortical thickness, assessment of gene by age interaction, several multivariate genetic analyses, and a search for genetically-mediated brain-behavioral relationships. These analyses …

Corticular Photosynthetic Dynamics For A Coastal Evergreen Shrub: Myrica Cerifera, Jaclyn K. Vick

Theses and Dissertations

I quantified seasonal variations in corticular photosynthesis in 1st through 5th order branches of Myrica cerifera L. (Myricaceae) in order to determine whether corticular photosynthesis contributes to whole plant carbon gain by reducing respirational CO2 loss. Maximum % refixation was 110 ± 39 % of CO2 efflux in the dark (Rd) in 1st order branches during winter, minimum was 18 ± 3 % in 5th order branches during summer. Variations in % refixation paralleled changes in photosynthetically active radiation (PAR). As light attenuated with increasing branch order % refixation decreased. Increased PAR in the winter due to a more sparse …

New Records Of Alien Mollusca In The Hawaiian Islands: Non-Marine Snails And Slugs (Gastropoda) Associated With The Horticultural Trade, Kenneth Hayes, C. Tran, Robert Cowie

Department of Biology Faculty Publications

The  nonmarine  snails  of  the  Hawaiian  Islands  have  been  cataloged  by  Cowie  (1997),reviewed by Cowie (1998a), and subsequent new records reported by Cowie (1998b, 1999,2000). The horticultural industry has been implicated in the transport and introduction ofsnails and slugs in various parts of the world (e.g., Robinson 1999; Barrientos 2000; Cowie&Robinson 2003; Robinson & Slapcinsky 2005), including Hawai‘i (e.g., Cowie 1998b,1999, 2000). Therefore, between 2004 and 2006 we undertook field surveys of nurseries,botanical gardens, and other similar facilities involved in the cultivation of plants, includ-ing aquatic plants, for sale, recreation or research on the six largest of the main HawaiianIslands, …

From Gps To Psychologists: The Patients' Perspective On Help-Seeking And Referral, Zdenka Bartova

Theses : Honours

The experience of living with psychological problems has a profound effect on an individual's life. For those actively seeking help, General Practitioners usually present the first point of contact. General Practitioners thus serve as gatekeepers who either decide to manage the individuals themselves and/or refer them to a mental health professional. The referral decision is part of a complex help-seeking process in which patients have to mediate their own understanding of their problems with that of the practitioner, all within the structural constraints of the current health care system. This literature review discusses constructs of mental illness and the impact …

Development Of A Blood Test For The Detection Of Cutaneous Malignant Melanoma, Rebecca Slattery

Theses : Honours

Cutaneous Malignant Melanoma is a highly aggressive form of skin cancer that has a tendency to metastasise. In its early stages, the 5-year survival rate of patients is greater than 90% following surgical excision of an in situ tumour. However, following metastasis of the tumour, the 5-year survival rate declines to 5-35%. Due to the correlation between metastasis and declining survival, studies have attempted to identify potential metastasis as early as possible. Molecular markers of melanoma cells in the peripheral blood of CMM patients have been investigated, as the invasion of tumour cells into the blood is one of the …

Teachers' Perceptions Of Sense Of Belonging And The Possible Impact On Adolescent Development, Debra E. York

Theses : Honours

The nature of adolescence has been identified as a time of vast biopsychosocial changes that take place within a dynamic environment. The interplay between the individual developmental changes and the surrounding changing environments has been considered in relation to the development of depression during adolescence. Research has indicated that depression elevates during adolescence (Cicchetti & Toth, 1998). Both normative and non-normative changes pertinent to the adolescent have been identified as risk factors. Social support from family, peers and teachers has been found to facilitate positive influences to the adolescent's psychological and emotional well being. Particularly the role teachers' play in …

A Study Of The Parallelisation Of Multiobjective Evolutionary Algorithms In A Cluster Environment, Sadeesha Gamhewa

Theses : Honours

The two main issues relating to the use of Multiobjective Evolutionary Algorithms (MOEAs) are the efficiency and effectiveness of the algorithms. As a result of the multiobjective and multi dimensional nature of MOEAs, the overall execution time that is taken to solve real world problems with MOEAs can be significant. Therefore, a few studies have recently been completed to address these performance issues by the use of parallelisation methods. The most widely known parallel Multiobjective Evolutionary Algorithm (pMOEA) models are the Master-slave, the Island, and the Diffusion models. The Master-slave and the Island models are generally implemented using message passing …

Electron Affinities, Solvation Energies And Redox Potentials Of Some Chalcones: Substituents` Effect And Correlation With Semi-Empirical Mo Energies, Abdur Rahman, Rumana Qureshi, Mehvish Kiran, Farzana Latif Ansari

Turkish Journal of Chemistry

Experimental and theoretical investigations were carried out on 2 sets of chalcones. Set 1 has an OH group on ring A and Set 2 does not, and both have different substituents on ring B at different positions. The experimental investigations comprised cyclic voltammetric (CV) studies to determine the reactivity in terms of redox potentials in DMF at room temperature (23 \pm 1 °C). Electrochemical parameters from cyclic voltammograms were used to evaluate the reversibility of electron transfer, standard reduction potentials, solvation energies, electron affinities, diffusion coefficients, critical scan rates and heterogeneous electron transfer rate constants. Heterogeneous electron transfer rate constants …

Cover And Contents

Turkish Journal of Chemistry

No abstract provided.

Iridoid Glucosides From Lamium Garganicum Subsp. Laevigatum, Tayfun Ersöz, Duygu Kaya, Funda Nuray Yalçin, Cavi̇t Kazaz, Erhan Palaska, Charlott H. Gotfredsen, Soren R. Jensen, İhsan Çaliş

Turkish Journal of Chemistry

Phytochemical investigations on the above-ground parts of Lamium garganicum subsp. laevigatum resulted in the isolation of 7 iridoid glucosides: shanzhiside methyl ester (1), barlerin (8-O-acetylshanzhiside methyl ester) (2), 6-O-syringyl-8-O-acetylshanzhiside methyl ester (3), 6\beta-hydroxyipolamiide (4), lamalbide (5), dehydropenstemoside (6), and sesamoside (7). The structure of the iridoids was elucidated by spectroscopic (UV, IR, 1D- and 2D-NMR, and ESI-MS) evidence.

Cover And Contents

Turkish Journal of Chemistry

No abstract provided.

An Electrochemical Dna Biosensor For The Detection Of Dna Damage Caused By Radioactive Iodine And Technetium, Pinar Kara, Kağan Dağdevi̇ren, Mehmet Özsöz

Turkish Journal of Chemistry

A DNA damage process by radioactive iodine (I-131) and technetium (Tc-99m) is described. The procedure relies on a label-free electrochemical DNA biosensor. Fish sperm double stranded DNA was immobilized onto a carbon paste electrode (CPE) by electro deposition and the changes to the guanine oxidation signal were observed upon exposure to radioactive I-131 and Tc-99m by differential pulse voltammetry (DPV). The changes to the signal of guanine after exposure to therapeutic doses of Tc-99m and I-131 showed conformational changes in DNA molecules.

Synthesis, Characterization, And Biocidal Studies Of The Newly Synthesized Di- And Triorganotin(Iv) Complexes With N-Butylhydrogen Phthalate, Sadiq-Ur Rehman, Saqib Ali, Saira Shahzadi, Abdul Malik, Ejaz Ahmed

Turkish Journal of Chemistry

Di-(1, 3, 8) and triorganotin(IV) complexes (2, 5, 7) with the general formula R_nSnL_{4-n}, where R = Me, Et, n-Bu, n-Oct, Ph, and Bz, and L = the n-C_4H_9OCOC_6H_4COO^- monoanionic ligand have been synthesized by the reaction of the silver salt of the n-butylhydrogen phthalate with di- and triorganotin chloride in dry chloroform. However, di-n-butyl- and di-n-octyltin(IV) derivatives (4 and 6, respectively) were synthesized by the reaction of the corresponding organotin(IV) oxide with n-butylhydrogen phthalate in dry toluene. All the synthesized complexes were characterized by elemental analysis, FT-IR, multinuclear (^1H, ^{13}C, ^{119}Sn) NMR, and mass spectrometric techniques to assess the …

Cover And Contents

Turkish Journal of Chemistry

No abstract provided.

Selenium And Trace Element Distribution In Astragalus Plants: Developing A Differential Pulse Polarographic Method For Their Determination, Güler Somer, A. Cengi̇z Çalişkan

Turkish Journal of Chemistry

Astragalus plants have a wide range of applications in pharmaceuticals (gum tragacanth), as thickening agents in foods, and may have applications in controlling cancer cells. They are used as feed for animals and they are indicator plants for selenium. Because of their use in health-related areas it is very important to determine their selenium and trace element content with high accuracy. A new differential pulse polarographic method was established for trace element determination (10 elements) and their distribution in these plants. The Astragalus plants investigated in this work are Astragalus microcephalus and Astragalus lusitanicus, which grow almost everywhere. Their roots, …

Preparation, Spectroscopy, Antimicrobial Assay, And X-Ray Structure Of Dimethyl Bis-(4-Methylpiperidine Dithiocarbamato-S,S`)-Tin(Iv), Zia-Ur Rehman, Saira Shahzadi, Saqib Ali, Guo-Xin Jin

Turkish Journal of Chemistry

Dimethyl bis(4-methylpiperidine dithiocarbamato-S,S')-tin(IV) was synthesized and characterized by elemental analysis, IR and mass spectrometry, multinuclear NMR (^1H- and ^{13}C-NMR), and X-ray single crystal analysis. IR data showed that the ligand acts as a bidentate in the solid state. X-ray data showed the unsymmetrical nature of the ligand towards coordination to tin. It crystallized in the monoclinic P2_1/n space group. Its geometry is distorted octahedral. Antimicrobial activity data shows that the complex exhibits significantly more activity than the free ligand.

The Synthesis Of 2-(Chloromethyl)-6-Hydroxy-2h-Pyran-3 (6h)-One Via Achmatowicz Rearrangement, Zuhal Gerçek

Turkish Journal of Chemistry

Achmatowicz rearrangement was carried out with 2-chloro-1-(furan-2-yl) ethanol, which was synthesized starting from 1-(furan-2-yl) ethanone. It was shown that the oxidation of 2-chloro-1-(furan-2-yl) ethanol with m-CPBA produced 2-(chloromethyl)-6-hydroxy-2H-pyran-3 (6H)-one in good yield (70%).

Drift Tube Ion Mobility Measurements For Thermochemistry, Kinetics And Polymerization Of Cluster Ions, Ridha Ben Mohsen Mabrouki

Theses and Dissertations

In this work, the Drift Tube Ion Mobility technique is used to study the hydrophobic hydration and solvation of organic ions and measure the thermochemistry and kinetics of ion-molecule reactions. Furthermore, an exploratory study of the intracluster polymerization of isoprene will be presented and discussed. The ion hydration study is focused on the C3H3+ cation1 and Pyridine▪+ radical cation.2 The chemistry of the cyclic C3H3+ cation1 has received considerable attention and continues to be an active area of research.3-7 The binding energies of the first 5 H2O molecules to c-C3H3+ were determined by equilibrium measurements. The measured binding energies of …

Genetic Variations In Interferon-Induced Genes And Hcv Recurrence After Liver Transplantation, Benjamin Cameron Whitehill

Theses and Dissertations

Hepatitis C Virus (HCV) infection represents a worldwide pandemic and is currently the leading cause of cirrhosis and liver transplantation. After transplantation recurrence is almost universal with 96% of patients testing positive for viral RNA and exhibiting histological evidence of infection within the first year. Type I interferons (IFN) and interferon inducible genes are responsible for the innate antiviral state and single nucleotide polymorphisms (SNPs) within these genes may affect the patients ability to respond post-transplantation. We hypothesize the elucidation of associations between SNPs in Type-I Interferon and Interferon inducible genes and HCV recurrence post-liver transplantation might help to identify …

Functional Neuroimaging And The Law: Trends And Directions For Future Scholarship, Stacey A. Tovino

Faculty Articles

Under the umbrella of the burgeoning neurotransdisciplines, scholars are using the principles and research methodologies of their primary and secondary fields to examine developments in neuroimaging, neuromodulation, and psychopharmacology. The path for advanced scholarship at the intersection of law and neuroscience may clear if work across the disciplines is collected and reviewed and outstanding and debated issues are identified and clarified. In this article, I organize, examine and refine a narrow class of burgeoning neurotransdiscipline scholarship; that is, scholarship at the interface of law and functional magnetic resonance imaging.

Psychiatric Restraint And Seclusion: Resisting Legislative Solution, Stacey A. Tovino

Faculty Articles

The use of restraint and seclusion in the American psychiatric setting has a rich history - rich in medical, ethical, legal, and social controversy. For centuries, mental health care providers used movement restrictions and solitary confinement to manage psychiatric patients. Superintendents of eighteenth and early nineteenth century insane asylums and other institutions of confinement believed that strait-waistcoats, "tranquilizer chairs," "maniac beds," chains, shackles, and "quiet rooms" deescalated agitation and promoted self-control. Reforms beginning in the nineteenth century helped make some psychiatric institutions more humane, in part because staff members were trained to find ways to calm potentially violent patients without …

Designing Classroom Management Training For Basic Course Instructors, Kevin R. Meyer, Cheri J. Simonds, Brent K. Simonds, John R. Baldwin, Stephen K. Hunt, Mark E. Comadena

Basic Communication Course Annual

Since many basic course training programs fail to adequately address classroom management issues, most graduate teaching assistants (GTAs) enter the classroom unprepared to confront student misbehaviors. However, literature suggests that by incorporating classroom management issues into training pro­grams, GTAs will be better armed to establish the instructional climate of the classroom and confront stu­dent misbehaviors. In this study, GTAs who had not received classroom management training (CMT) were given a survey containing closed and open-ended questions regarding typical student misbehaviors, possible classroom responses to those behaviors, and preferences for classroom management information during training. The results of this study identify …

Creating Sites For Connection In The Classroom: Dialogism As A Pedagogy For Active Learning, Melissa A. Broeckelman

Basic Communication Course Annual

Public speaking pedagogy should be based in communication theory, but as a whole, our discipline has failed to integrate theory and praxis in the classroom. Dialogism is a good starting point for developing the­ory-based pedagogical strategies and is further supported by Vygotsky’s zones of proximal development, Dewey and Bruner’s call for experience-based learning, and research on collaborative learning. Here, I propose four specific strategies for incorporating dialogism into the pedagogy of public speaking courses: (a) use detailed grading rubrics to create a shared meaning of expectations before, during, and after the speech-building process, (b) give instructor feedback on outlines prior …

Gay Marriage In Rhode Island: A Big Issue In A Small State, Joan Catherine Bohl

Roger Williams University Law Review

No abstract provided.

[Introduction To] The Latino Body: Crisis Identities In American Literary And Cultural Memory, LáZaro Lima

Bookshelf

The Latino Body tells the story of the United States Latino body politic and its relation to the state: how the state configures Latino subjects and how Latino subjects have in turn altered the state. Lázaro Lima charts the interrelated groups that define themselves as Latinos and examines how these groups have responded to calls for unity and nationally shared conceptions of American cultural identity. He contends that their responses, in times of cultural or political crisis, have given rise to profound cultural transformations, enabling the so-called “Latino subject“ to emerge.

Analyzing a variety of cultural, literary, artistic, and popular …

Understanding The Personal And Clinical Utility Of Psychiatric Advance Directives: A Qualitative Perspective, Mimi M. Kim, Richard A. Van Dorn, Anna M. Scheyett, Eric E. Elbogen, Jeffrey W. Swanson, Marvin S. Swartz, Laura A. Mcdaniel

Faculty and Staff Publications

Psychiatric advance directives (PADs) are legal tools that allow competent individuals to declare preferences for future mental health treatment when they may not be capable of doing so as a result of a psychiatric crisis. PADs allow individuals to maintain self–determination during times when they are most vulnerable to loss of autonomy and in need of assistance to make their preferences known and honored. This article describes the content of twenty–eight open–ended, semi–structured qualitative interviews of adults with PADs who have experienced psychiatric crises. The qualitative analysis revealed three major themes from the interviews: (1) PADs as tools for empowerment …

Whole Genome Duplications And Contracted Breakpoint Graphs, Max A. Alekseyev, Pavel A. Pevzner

Faculty Publications

The genome halving problem, motivated by the whole genome duplication events in molecular evolution, was solved by El-Mabrouk and Sankoff in the pioneering paper [SIAM J. Comput., 32 (2003), pp. 754–792]. The El-Mabrouk–Sankoff algorithm is rather complex, inspiring a quest for a simpler solution. An alternative approach to the genome halving problem based on the notion of the contracted breakpoint graph was recently proposed in [M. A. Alekseyev and P. A. Pevzner, IEEE/ACM Trans. Comput. Biol. Bioinformatics, 4 (2007), pp. 98–107]. This new technique reveals that while the El-Mabrouk–Sankoff result is correct in most cases, it does not hold in …

Colored De Bruijn Graphs And The Genome Halving Problem, Max A. Alekseyev, Pavel A. Pevzner

Faculty Publications

Breakpoint graph analysis is a key algorithmic technique in studies of genome rearrangements. However, breakpoint graphs are defined only for genomes without duplicated genes, thus limiting their applications in rearrangement analysis. We discuss a connection between the breakpoint graphs and de Bruijn graphs that leads to a generalization of the notion of breakpoint graph for genomes with duplicated genes. We further use the generalized breakpoint graphs to study the Genome Halving Problem (first introduced and solved by Nadia El-Mabrouk and David Sankoff). The El-Mabrouk-Sankoff algorithm is rather complex, and, in this paper, we present an alternative approach that is based …