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Exploring The Ligand Binding Site On The Dopamine Transporter By Photoaffinity Labeling And Site-Directed Mutagenesis, Maria Laura Parnas

Theses and Dissertations

The dopamine transporter (DAT) is a neuronal presynaptic transmembrane protein that clears released dopamine (DA) from the synaptic space, regulating the neurotransmitter concentration and availability, DAT and the related serotonin (SERT) and norepinephrine (NET) transporters belong to the SLC6 family of Na+ and CI- dependent symporters, and are major targets for the action of several drugs, including the psychostimulant cocaine. DAT is predicted to possess 12 transmembrane spanning domains (TMs), with both N- and C-termini located intracellularly. Extensive research efforts to gain insight on the molecular aspects of DAT have been attempted, but the three-dimensional arrangement of the protein as …

A Corpus-Based Synchronic Comparison And Diachronic Interpretation Of Lexicalized Emotion Metaphors In English And Chinese, Shixiong, George Wu

Lingnan Theses

This study is a corpus-based contrastive study of the cross-language diachronic changes and synchronic variations of lexicalized emotion metaphors (LEMS) in English and Chinese within the framework of cognitive linguistics. Since it is based on a series of basic assumptions of the Lakoffian Conceptual Metaphor Theory (CMT), it is also expected to prove or improve them by making this cross-cultural comparative study of LEMS in English and Chinese. Therefore this study aims at not only the diachronic changes and synchronic variations of LEMS but also the cultural factors underlying them. By applying CMT in the analysis of the corresponding data …

Airport Security: Examining The Current State Of Acceptance Of Biometrics And The Propensity Of Adopting Biometric Technology Fo, Kristine Sumner

Electronic Theses and Dissertations

The terrorist attacks of September 11, 2001 propelled the issue of aviation security to the forefront of the U.S. domestic agenda. Although hundreds of individual airports exist in the U.S., the travel activities at each of these airports combine to holistically comprise an aviation system that represents a significant portion of the U.S. social and economic infrastructure. Disruption at one airport resulting from a criminal act, such as terrorism, could exert detrimental effects upon the aviation system and U.S national security (9/11 Commission, 2004). Each U.S. airport is individually responsible for various aspects of security including the control of physical …

Ellen White's Interpretation And Use Of The Seven Letters Of Revelation, Denis Fortin

Journal of the Adventist Theological Society

No abstract provided.

Smoke And Mirrors: A Cultural-Psychological Analysis Of Tobacco Use, Michael Melczak

Electronic Theses and Dissertations

This theoretical dissertation explores tobacco use from the perspectives of social constructivism and phenomenological depth psychology. In Part I, tobacco use is described as a cultural artifact, and transformations in tobacco use are traced through three different cultural contexts or "worlds": the indigenous or aboriginal worldview, the European and American worldview of the 17th through mid-19th centuries, and the modern American worldview (or "modernity"). In each of these worldviews, the cultural context informed and influenced (or reflected and reproduced) understandings of tobacco use. One notices the transformation of tobacco use, for example, from a god to a commodity and from …

Developmental Variations In Plasma Leptin, Leptin Soluble Receptor And Their Molar Ratio In Healthy Infants, Winston Wk Koo, Mouhanad Hammami, Elaine M. Hockman

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Leptin and its soluble receptor (sOB-R) are important to regulation of body composition but there are no data on the developmental variations in these plasma variables and their relationship with body composition measurements,

Methods

Weight, length, and body composition (bone, fat and lean mass) by dual energy absorptiometry, and plasma variables were measured in healthy infants at 2, 4, 8 and 12 months.

Results

15 whites and 29 African Americans (21 males and 23 females) with mean birth weight 3357 +/- 45 (SEM) g and gestation of 39.3 +/- 0.17 weeks were studied. The overall Z score for …

An Analysis Of Intuitive Eating Among College Students, Danielle Marie Vsetecka

Dissertations and Theses @ UNI

In response to the world's increasing obesity rates, the use of traditional dieting and weight loss techniques is at an all time high. Although dieting rates have rapidly increased, the world's rising obesity rates show no sign of slowing and the effectiveness and effects of dieting have long been questioned. As an alternative to dieting and exercise, a non-dieting approach to weight regulation has emerged. Intuitive eating is one of its main tenants and is defined by allowing individuals to listen to internal body cues to determine hunger and fullness levels to meet nutritional and physical needs. However, few studies …

The Use Of A Chiral Fluorescent Resorcinarene For The Enantiomeric Recognition Of Amino Acids, Gerald I. Richard

LSU Master's Theses

The spectroscopic properties of a chiral boronic acid based resorcinarene macrocycle employed for chiral analysis were investigated. Specifically, the emission and excitation characteristics of tetraarylboronate resorcinarene macrocycle (TBRM) and its quantum yield were evaluated. The chiral selector TBRM was investigated as a chiral reagent for the enantiomeric discrimination of amino acids using steady-state fluorescence spectroscopy. Chiral recognition of amino acids in the presence of the macrocycle was based on diastereomeric complexes. Results demonstrated that TBRM had better chiral discrimination ability for lysine as compared to the other amino acids. Partial-least-squares regression modeling (PLS-1) of spectral data for macrocycle-lysine host-guest complexes …

Genotypic Variability And Inheritance Of Iron And Zinc In Sweetpotato, Michael William Courtney

LSU Master's Theses

Sweetpotato [Ipomœa batatas (L.) Lam.] is a major subsistence crop in Sub-Saharan Africa, where iron and zinc deficiency in humans is an important health problem. A sweetpotato cultivar suited for subsistence farming, with high iron and zinc concentration, would be important in alleviating these deficiencies. The main objective of this research was to identify the extent of genetic variability of iron and zinc concentration in sweetpotato germplasm. An important subcomponent of this research was to determine the heritability of iron and zinc in sweetpotato. Protocol development studies were also conducted to aid in determining proper sampling technique. The results of …

A New Questionnaire To Determine The Frequency And Severity Of Symptoms Caused By Inhaled Odors, Chemicals And Irritants In Normal Subjects And Their Relation To Health-Related Quality Of Life, Stephen E. Williamson

USF Tampa Graduate Theses and Dissertations

Individuals may develop symptoms in response to inhaled odors, chemicals, and irritants. This may affect their quality of life. Little is known about the prevalence and severity of symptoms that result from exposure to odors, chemicals and irritants. This study demonstrates the development of a new respiratory questionnaire to detect the prevalence and severity of symptoms experienced upon exposure to chemicals, odors, and irritants, and relates these symptoms to quality of life. This questionnaire was submitted to 96 volunteers at the University of South Florida College of Public Health who responded to items regarding symptoms developed in response to exposure …

Creator, Creation, And Church: Restoring Ecology To Theology, Joann Davidson

Andrews University Seminary Studies (AUSS)

No abstract provided.