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2006

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The Impact Of High Density Lipoprotein Cholesterol On Five-Year Mortality In Older Adults, Lisa Millman Nov 2006

The Impact Of High Density Lipoprotein Cholesterol On Five-Year Mortality In Older Adults, Lisa Millman

Yale Medicine Thesis Digital Library

The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III) guidelines have defined a high density lipoprotein cholesterol (HDL-C) of <50 mg/dL in women and <40 mg/dL in men as a risk factor for cardiovascular disease. Our research aim was to examine the relationship between untreated HDL-C levels below this recommended level on five year cardiovascular, stroke, and all-cause mortality in adults over 71 years of age. The Established Populations for Epidemiologic Studies of the Elderly (EPESE) is a prospective cohort study of community dwelling adults over 65 years of age in East Boston, MA; Iowa and Washington Counties, IA; New Haven, CT; and Durham, NC. The National Institutes of Aging (NIA) started EPESE to study health, social, psychological, and economic aspects of older adults lives through extensive annual interviews. The EPESE dataset is further enriched by serum measures including low-density lipoprotein cholesterol (LDL-C), HDL-C, total cholesterol, triglycerides, glucose, BUN and creatinine, which were obtained at the sixth annual follow-up interview. Our primary outcome was all-cause mortality with secondary mortality outcomes of acute myocardial infarction (AMI), coronary artery disease (CAD) not AMI, and congestive heart failure (CHF). The mean age of our cohort was 78.7 years with the majority being female (63.86%), white (88.15%), and married (52.80%). Just over half (52.07%) of our cohort met the criteria for low HDL-C as defined by ATP III. Chi square and Fisher exact test were used to compare demographics (age, gender, race, marital status, education), clinical variables (history of MI, cancer, diabetes, angina, smoking, alcohol use), and functional variables (activities of daily living, gross mobility, cognitive status) at baseline and five year follow-up. Cox proportional hazard models were created using a step-wise approach to assess the impact of low HDL-C on mortality. Low HDL-C was not significantly associated with crude all-cause (P= .413), AMI (P= .473), CHF (P= .259), and stroke (P= .345) mortality. HDL-C was significantly associated with unadjusted CAD (P= .033) mortality. However, after adjustment for demographics, clinical, and functional variables as well as the other blood values all outlined above, HDL-C was not associated with five year all-cause, AMI, CAD, CHF or stroke mortality with adjusted hazard ratios of (HR=1.03, 95% CI 0.90-1.18), (HR=1.09, 95% CI 0.70-1.71), (HR=1.33, 95% CI 0.91-1.92), (HR=1.07, 95% CI 0.63-1.81) and (HR=0.80, 95% CI 0.51-1.27) respectively. In older community dwelling adults enrolled in EPESE, low HDL-C levels as stratified by current recommended guidelines (<50 mg/dL in women and <40 mg/dL in men) were not associated with increased risk of five-year cardiovascular, stroke or all-cause mortality. HDL-C alone may have minimal effect on future longevity in older adults due to competing risk and co-morbid conditions. Further studies are required to determine whether the movement toward more aggressive lipid profile interventions specifically to raise HDL-C in older adults would prove beneficial in this growing segment of our population.


Quality Of Life In Macular Degeneration Between Photodynamic Therapy And Pegaptanib Treatment Groups, Sara Nayeem Nov 2006

Quality Of Life In Macular Degeneration Between Photodynamic Therapy And Pegaptanib Treatment Groups, Sara Nayeem

Yale Medicine Thesis Digital Library

The purpose of this study was to examine quality of life (QOL) in age-related macular degeneration (AMD), particularly across photodynamic therapy (PDT) and pegaptanib sodium injection treatment groups. Patients with AMD were either mailed or were administered in person a modified version of the Visual Function Questionnaire (VFQ-25). Subgroup analysis of the VFQ-25 was performed per NEI prescribed algorithms and additional analyses regarding questions on treatment side effects were also performed. A two-tailed student t-test and mean were calculated for each treatment group and correlations between visual acuity and subgroup outcomes were calculated. Correlations between the subgroup and treatment-related subgroup …


The Physiological Effects Of Hockey Protective Equipment On High Intensity Intermittent Exercise, Benjamin Noonan Nov 2006

The Physiological Effects Of Hockey Protective Equipment On High Intensity Intermittent Exercise, Benjamin Noonan

Yale Medicine Thesis Digital Library

Ice hockey is a contact sport played in a cold environment which leads to assumptions that players are not exposed to a thermal challenge. The purpose of this study was to test the hypothesis that the wearing of hockey protective equipment during an exercise protocol designed to simulate a hockey game would induce a thermal challenge and lead to decrements in performance. In order to test this hypothesis and qualify the physiological responses, subjects performed a standardized protocol performed on a stationary cycle ergometer in an environmental chamber set at typical (12ºC) ice hockey ambient conditions. The simulation was performed …


Effect Of Soy Isoflavone Protein And Soy Lecithin On Endothelial Function In Healthy Postmenopausal Women, Mary Pearson Nov 2006

Effect Of Soy Isoflavone Protein And Soy Lecithin On Endothelial Function In Healthy Postmenopausal Women, Mary Pearson

Yale Medicine Thesis Digital Library

The purpose of this study was to assess the effects of soy isoflavone protein concentrate and soy lecithin on endothelial function measured as flow mediated dilation (FMD) of the brachial artery in healthy postmenopausal women. In this randomized, double-blind, placebo controlled crossover trial, twenty-five subjects (mean age 61 years; BMI 25.46 kg/m2) were recruited from the general population of southwestern Connecticut. Subjects underwent endothelial function testing using high frequency ultrasound at baseline and following 4 weeks of each randomly assigned treatment with intervening 4-week washout periods. Treatment assignment included: soy isoflavone protein (SP, 25gm/day) or soy lecithin (SL, 20gm/day) alone …


Social Influences On Academic Motivation In Early Elementary School Students, Jenli Waters Nov 2006

Social Influences On Academic Motivation In Early Elementary School Students, Jenli Waters

Yale Medicine Thesis Digital Library

The goal of this research is to identify correlations between academic intrinsic motivation and exposures to academic activities within the home acknowledged by young children (5 to 8 years old). This study hopes to clarify relationship between academic intrinsic motivation and exposure to positive role modeling of academic activities in young children. Much of the data was collected by interview-style surveys conducted with a sample of 18 boys and girls of ages between 5 and 8 years. The Child-Reported Home Reading and Math Exposure Questionnaire (HEQ) was developed by the author for this study to assess the extent to which …


The Effects Of Posttraumatic Stress Disorder On Pregnancy Outcomes, Shari Rogal Nov 2006

The Effects Of Posttraumatic Stress Disorder On Pregnancy Outcomes, Shari Rogal

Yale Medicine Thesis Digital Library

The purpose of this study was to determine the effect of posttraumatic stress disorder (PTSD), diagnosed prospectively during pregnancy, on the occurrence of low birthweight (<2500 grams) and preterm delivery (<37 weeks gestational age). A cohort of 1362 women was recruited from prenatal care visits and screened for depression, panic disorder, posttraumatic stress disorder, and substance use. Current episodes of PTSD were assessed using the MINI International Neuropsychiatric Interview. Pregnancy outcomes were abstracted from hospital records after delivery, and the data were analyzed using logistic regression. Two hundred sixty two women (33%) were lost to follow-up due to unavailable medical records, leaving 1100 women in the final analyses. Among these 1100 women, 31 (3%) were found to have PTSD during pregnancy. Substance use in pregnancy, panic disorder, major and minor depressive disorders, and prior preterm delivery were significantly associated with PTSD in the sample, while age, language spoken, and race were not. Low birthweight (LBW) was present in 6.5% of sampled women and was not significantly associated with a diagnosis of PTSD in pregnancy when adjusting for potential confounders. However, LBW was significantly associated with minor depressive disorder OR= 1.82 (CI=1.01, 3.29). Preterm delivery occurred in 7.0% of those without and 16.1% of those with PTSD (p=0.055). Because prior preterm delivery data were not available for 33% of women with PTSD, this variable was included only in secondary analyses. However, the association between PTSD and preterm delivery depended on this variable, with OR= 2.82 (0.95, 8.38) before controlling for prior preterm delivery and OR=3.35 (1.04, 10.85) after controlling for prior preterm delivery. These data suggest that a possible association of PTSD and preterm delivery was limited by the low rates of PTSD in this cohort and the inability to control for all confounders. Taken together, these findings provide limited support for the hypothesized association between PTSD and preterm delivery and no support for an association of PTSD with LBW.


The Anchor, Volume 120.09: November 15, 2006, Hope College Nov 2006

The Anchor, Volume 120.09: November 15, 2006, Hope College

The Anchor: 2006

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.


Campus Chronicle, Jeni Gieseke, Alex Middleton, Jeremy Harmsen, Megan Lyon, Jesi Landwier, Malina Doke, Malin Cheney Nov 2006

Campus Chronicle, Jeni Gieseke, Alex Middleton, Jeremy Harmsen, Megan Lyon, Jesi Landwier, Malina Doke, Malin Cheney

Campus Chronicle

No abstract provided.


November 15th 2006, Hispanic News Nov 2006

November 15th 2006, Hispanic News

Inland Empire Hispanic News

No abstract provided.


Prevalence Of Pain In The Medical Intensive Care Unit, Jennifer Smith Nov 2006

Prevalence Of Pain In The Medical Intensive Care Unit, Jennifer Smith

Yale Medicine Thesis Digital Library

N/A (long introduction)


The Effect Of General Anesthesia On Acupuncture: A Functional Mri Study, Dana Weiss Nov 2006

The Effect Of General Anesthesia On Acupuncture: A Functional Mri Study, Dana Weiss

Yale Medicine Thesis Digital Library

We performed a study to examine brain activity as assessed by functional-MRI when acupuncture is administered to awake volunteers as compared to acupuncture administered to volunteers under general anesthesia. Healthy, acupuncture-naive volunteers were recruited for this cross-over study. Volunteers underwent two experimental sessions that included a sequence of 4-20 seconds of on and off manual acupuncture stimulation for a period of 3 minutes while awake and while under propofol general anesthesia. The acupuncture intervention was performed at left stomach 36. General anesthesia was induced and maintained with propofol. BOLD signal images were obtained in a 1.5 T MRI scanner in …


Panther- November 2006 - Vol. Lxxxv No. 11, Prairie View A&M University Nov 2006

Panther- November 2006 - Vol. Lxxxv No. 11, Prairie View A&M University

PV Panther Newspapers

No abstract provided.


Ke Alakai, Vol. 76, No. 12 (2006-11-15), Brigham Young University Hawaii Nov 2006

Ke Alakai, Vol. 76, No. 12 (2006-11-15), Brigham Young University Hawaii

Ke Alaka'i

No abstract provided.


Pain As The Subjective Fifth Vital Sign Among Patients Undergoing Knee Or Hip Arthroplasty, Lindsey Sukay Nov 2006

Pain As The Subjective Fifth Vital Sign Among Patients Undergoing Knee Or Hip Arthroplasty, Lindsey Sukay

Yale Medicine Thesis Digital Library

The purpose of this study was, among patients undergoing knee or hip arthroplasty, to examine patients expectations for and experiences of postoperative pain, their perceptions of the quality of their pain management, and to identify potential barriers to effective pain management. This was a prospective cohort study of 68 patients undergoing knee or hip arthroplasty at Yale-New Haven Hospital. Patients were interviewed within 48 hours after surgery using a modified version of the American Pain Society Satisfaction Survey and were asked the amount of pain they expected to have postoperatively (EP) and the actual pain that they experienced in the …


Injection And Non-Injection Drug Users' Beliefs On Mandatory Newborn Hiv Testing Laws In The State Of Connecticut, Odicie Fielder Nov 2006

Injection And Non-Injection Drug Users' Beliefs On Mandatory Newborn Hiv Testing Laws In The State Of Connecticut, Odicie Fielder

Yale Medicine Thesis Digital Library

We examined health beliefs among drug users about mandatory HIV testing of newborns and voluntary versus mandatory testing of pregnant women. We also examined to what extent negative experiences and stigmatization affect attitudes towards HIV testing. Baseline structured interviews of active drug users from 1997-2001 were examined. Multivariate data analysis was performed using SAS statistical software. Subsequently, five distinct focus groups were conducted in September 2003. Focus groups were transcribed, coded and analyzed using Microsoft Word 2000. Of 610 drug users interviewed, nearly all (89%) had been previously HIV tested. Nearly all (91%) subjects believed pregnant women should be tested …


Student Life, November 15, 2006 Nov 2006

Student Life, November 15, 2006

Student Life Newspapers

November 15, 2006 issue of Student Life, the independent newspaper of Washington University in St. Louis since 1878. 2006-2007 academic year. Permanent URL: https://doi.org/10.7936/K7X63M1Q


Montana Kaimin, November 15, 2006, Students Of The University Of Montana, Missoula Nov 2006

Montana Kaimin, November 15, 2006, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula. Page 3 is missing.


Spectator 2006-11-15, Editors Of The Spectator Nov 2006

Spectator 2006-11-15, Editors Of The Spectator

The Spectator

No abstract provided.


Understanding Psychological Control Through Differences Between Shame And Disappointment: Implications For Childhood Agression, Sacha Leah Bikhazi Nov 2006

Understanding Psychological Control Through Differences Between Shame And Disappointment: Implications For Childhood Agression, Sacha Leah Bikhazi

Theses and Dissertations

The purpose of this study was to examine the potentially unique roles that parental use of two psychological control dimensions, shame and disappointment, play in predicting children's relational and physical aggression. It was additionally of interest to investigate whether warm/involved parenting would moderate the effects of these forms of psychological control on both types of childhood aggression. Based on a review of literature, it was hypothesized that parental use of shame would positively predict aggression in children, whereas parental use of disappointment would not be significantly associated with childhood aggression. Additionally, it was hypothesized that warm, involved parenting would have …


October 25, 2006 Armstrong Graduate Curriculum Committee Minutes, Armstrong State University Nov 2006

October 25, 2006 Armstrong Graduate Curriculum Committee Minutes, Armstrong State University

Armstrong Faculty Senate: Graduate Curriculum Committee Minutes (Archived)

October 25, 2006 Armstrong Graduate Curriculum Committee Minutes


Dual Enrollment: Measuring Factors For Rural High School Student Participation, Todd E. Johnson, Michael Brophy Nov 2006

Dual Enrollment: Measuring Factors For Rural High School Student Participation, Todd E. Johnson, Michael Brophy

The Rural Educator

The purpose of this study was to explore the reasons 162 rural area high school students participate in the dual enrollment program. Dual enrollment programs allow high school students to enroll in college courses for credit prior to high school graduation with local school districts covering the cost of tuition. Participants in this study were recruited from two rural agricultural counties from Washington State attending a local college. Exploratory factor analysis revealed that dual enrollment participation was related to academics, financial, social, and choice reasons. Results showed no significant differences between 11th and 12th grade participants regarding financial and choice …


It's Happening At State: November 15, 2006 Nov 2006

It's Happening At State: November 15, 2006

It's Happening at State

Provides summary information of news and events of interest to the faculty and staff of NDSU.


Zambian Ambassador Give Keynote Speech Nov. 16 During International Education Week, Public Affairs Office Nov 2006

Zambian Ambassador Give Keynote Speech Nov. 16 During International Education Week, Public Affairs Office

Press Releases

No abstract provided.


The Bates Student - Volume 136 Number 08 - November 14, 2006, Bates College Nov 2006

The Bates Student - Volume 136 Number 08 - November 14, 2006, Bates College

The Bates Student

No abstract provided.


Volume 44, Number 25: November 14, 2006, University Of North Dakota Nov 2006

Volume 44, Number 25: November 14, 2006, University Of North Dakota

University Letter Archive

No abstract provided.


Newman And The Restoration Of The Interpersonal In Higher Education, Michael J. Buckley S.J. Nov 2006

Newman And The Restoration Of The Interpersonal In Higher Education, Michael J. Buckley S.J.

Santa Clara Lectures

No abstract provided.


Mustang Daily, November 14, 2006 Nov 2006

Mustang Daily, November 14, 2006

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.


Flyer News, Vol. 54, No. 15 (Nov. 14, 2006), University Of Dayton Nov 2006

Flyer News, Vol. 54, No. 15 (Nov. 14, 2006), University Of Dayton

Flyer News

Student-run newspaper of the University of Dayton


The Hilltop 11-14-2006, Hilltop Staff Nov 2006

The Hilltop 11-14-2006, Hilltop Staff

The Hilltop: 2000 - 2010

No abstract provided.


Bringing Evidence-Based Child Mental Health Services To The Schools: General Issues And Specific Populations, Carrie Masia-Warner, Douglas W. Nangle, David J. Hansen Nov 2006

Bringing Evidence-Based Child Mental Health Services To The Schools: General Issues And Specific Populations, Carrie Masia-Warner, Douglas W. Nangle, David J. Hansen

Department of Psychology: Faculty Publications

Epidemiological research indicates a high prevalence of psychiatric disorders among children and adolescents. Approximately 21% of children and adolescents, ages 9 to 17, have a diagnosable psychiatric disorder (Costello et al., 1996; Shaffer et al., 1996; U.S. Public Health Service, 2000), and additional youngsters experience social and emotional difficulties that do not meet symptom criteria for a disorder but cause considerable distress and impairment in functioning. Unfortunately, there is a significant gap between the many youth who are in need of treatment and those who actually receive menfal health care (Burns et al., 1995; Leaf et al., 1996). According to …