Digital Commons Network^™

New Spiked-In Probe Sets For The Affymetrix Hgu-133a Latin Square Experiment, Monnie Mcgee, Zhongxue Chen

COBRA Preprint Series

The Affymetrix HGU-133A spike in data set has been used for determining the sensitivity and specificity of various methods for the analysis of microarray data. We show that there are 22 additional probe sets that detect spike in RNAs that should be considered as spike in probe sets. We assign each proposed spiked-in probe set to a concentration group within the Latin Square design, and examine the effects of the additional spiked-in probe sets on assessing the accuracy of analysis methods currently in use. We show that several popular preprocessing methods are more sensitive and specific when the new spike-ins …

Mustang Daily: Graduation 2006, June 9, 2006

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Washington University Record, June 9, 2006

Washington University Record

No abstract provided.

Educational Policies Committee Program Proposal, College Of Science, June 9, 2006, Utah State University

Educational Policies Committee

Utah State University requests approval to offer a Master of Science Degree in Applied Environmental Geoscience in the Department of Geology effective Fall Semester 2006.

Educational Policies Committee Program Proposal, College Of Humanities And Social Sciences, June 9, 2006, Utah State University

Educational Policies Committee

Utah State University requests approval to offer a Bachelor of Science Degree in Agricultural Communication and Journalism through the Department of Agricultural Systems Technology and Education effective Fall 2006.

Workshop Promotes Values Of Sustainability Among Iwu Faculty, Staff, Ann Aubry

News and Events (Discontinued Series)

No abstract provided.

Krohn Receives Men's Honor Athlete Award, University Relations

Campus News Archive

Austin Krohn ’06, Pierz, honored for academic and athletic achievement during his UMM career, will attend the University of Minnesota School of Medicine this fall.

The Relationship Of Implicit Family Process Rules To Adolescent Presentation Of Psychological Systems, Ian David Feinauer

Theses and Dissertations

Implicit family process rules refer to unspoken rules about family beliefs and expectations about communication, closeness, and organization and are an important dimension of family functioning that may have a powerful influence over adolescent psychological well being. This study focused on the relationship between implicit family process rules and adolescent psychological symptoms such as: Hostility, interpersonal sensitivity, depression, anxiety, and somatization. It was hypothesized that more facilitative implicit family process rules would be related to fewer adolescent psychological symptoms. In addition, a model was created that included theexogenousindependent variables of family status, (defined as intact-marriage or non-intact), treatment status (whether …

Metal-Organic Networks Based Upon Dicarboxylato Ligands, Zhenqiang Wang

USF Tampa Graduate Theses and Dissertations

Network structures based upon metal-organic backbones represent a new class of functional materials that can be rationally constructed by employing the concepts of supramolecular chemistry and crystal engineering. The modularity of design strategies, the diversity of prototypal structures, and the dynamic features of networks have afforded great advantages over traditional materials syntheses. The research presented in this thesis is primarily concerned with developing an in-depth understanding of the basic principles that govern the supramolecular behaviors of metal-organic networks and gaining an experimental control over the structure and function of these new classes of hybrid materials.

The use of rigid and …

Investigating The Role Of Small, Acid-Soluble Spore Proteins (Sasps) In The Resistance Of Clostridium Perfringens Spores To Heat., Deepa Raju, Michael Waters, Peter Setlow, Mahfuzur R Sarker

SoM Articles

BACKGROUND: Clostridium perfringens type A food poisoning is caused by enterotoxigenic C. perfringens type A isolates that typically possess high spore heat-resistance. The molecular basis for C. perfringens spore heat-resistance remains unknown. In the current study, we investigated the role of small, acid-soluble spore proteins (SASPs) in heat-resistance of spores produced by C. perfringens food poisoning isolates.

RESULTS: Our current study demonstrated the presence of all three SASP-encoding genes (ssp1, 2 and 3) in five surveyed C. perfringens clinical food poisoning isolates. beta-Glucuronidase assay showed that these ssp genes are expressed specifically during sporulation. Consistent with these expression results, our …

Murray Ledger And Times, June 8, 2006, Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Librarians In The Woods Hole Biomedical Informatics Course, Jane Bridges, Christian J Miller, Daniel G. Kipnis

Academic Commons and Scott Memorial Library Staff Papers and Presentations

What has come to be known as the "Woods Hole course," Biomedical Informatics, is a week-long course sponsored by the National Library of Medicine which has been offered since 1992. Its participants include librarians, clinicians, educators, and administrators. This article discusses the content of the course and its applicability to medical librarians.

Influence Of Age On Auditory Gating, Ginny Marissa Smith

Theses and Dissertations

This study utilized paired tones at 1000 Hz with a 500 ms interpair interval and a 10 s interstimulus interval to assess sensory gating. Forty-two participants, ranging from 3-72 years of age were used to observe maturational changes in amplitude, latency, and suppression ratios of the P50 waveform. Previous research has shown that in normal adults the amplitude in response to the second of the paired tones is significantly suppressed compared to the amplitude in response to the first tone. The current study showed amplitude decreased with age to middle adulthood, where it increased slightly to later adulthood. Latencies decreased …

Intermediary Metabolism And Life-History Trade-Offs: Differential Metabolism Of Amino Acids Underlies The Dispersal-Reproduction Trade-Off In A Wing-Polymorphic Cricket, Anthony J. Zera, Zhangwu Zhao

Anthony Zera Publications

Although the differential flow of metabolites through alternate pathways of intermediary metabolism is thought to be an important functional cause of life-history trade-offs, this phenomenon remains understudied. Using a radiolabeled amino acid, we quantified genetic differences in in vivo amino acid metabolism between morphs of the wing-polymorphic cricket Gryllus firmus that trade off early-age reproduction and dispersal capability. Lines selected for the flight-capable morph, which delays reproduction, oxidized a greater proportion of radiolabeled glycine and converted a greater amount into somatic lipid, mainly triglyceride (flight fuel). By contrast, lines selected for the flightless, reproductive morph converted a substantially greater proportion …

Modelling Wildlife Rabies: Transmission, Economics, And Conservation, Ray T. Sterner, Graham C. Smith

United States Department of Agriculture Wildlife Services: Staff Publications

Rabies is a fatal zoonotic disease of mammals; it exacerbates the uncertainty of conserving populations of some threatened mammals (TM). Modeling affords an inexpensive, a priori way of studying key parameters of wildlife rabies transmission, rabies management economics, and TM conservation. Numerous models of rabies transmission have been published. Linear density dependent models predicted that a threshold density (KT 6 1.0), possibly attained by culling or contraception, would eliminate an epizootic through reduced contacts among host animals. Density independent models predicted less advantage of culling and contraception in rabies control due to limited contacts among territorial host animals. Recent stochastic, …

The (Intellectual Property Law &) Economics Of Innocent Fraud: The Ip & Development Debate, Peter Matthew Beattie

ExpressO

This note/essay examines the evidence on the effect of stronger IP laws introduced during the process of international IP law harmonization initiated by the TRIPS agreement, on the economic development of developing countries. It has been argued by proponents of harmonization that stronger IP laws will provide a needed boost to the economic development of developing (and even least-developed) countries. Critics of harmonization have argued that stronger IP laws will have the opposite effect. What has been largely overlooked in this debate is the strength of the evidentiary foundation upon which the arguments of both sides depend. Many of the …

The Demanding Community: Politicization Of The Individual After Dewey, Matthew C. Flamm

Education and Culture

This article argues that conceptions of community after Dewey despair of an institutional means of recovering individuality, which is the central problem of democracy. They so despair, I contend, because of their politicized view of the individual. I first briefly consider the contrast between Dewey and contemporary proceduralists and civic republicans, before turning to my central discussion: C. Wright Mills, whose critique indicates a historical watershed for Dewey’s view of community. Ultimately, despair of a Deweyan sense of community issues in a contemporary stalemate between what I identify as the political “activist” and “apathist.”

June 7, 2006 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

A Faster Circular Binary Segmentation Algorithm For The Analysis Of Array Cgh Data, E S. Venkatraman, Adam Olshen

Memorial Sloan-Kettering Cancer Center, Dept. of Epidemiology & Biostatistics Working Paper Series

Motivation: Array CGH technologies enable the simultaneous measurement of DNA copy number for thousands of sites on a genome. We developed the circular binary segmentation (CBS) algorithm to divide the genome into regions of equal copy number (Olshen {\it et~al}, 2004). The algorithm tests for change-points using a maximal $t$-statistic with a permutation reference distribution to obtain the corresponding $p$-value. The number of computations required for the maximal test statistic is $O(N^2),$ where $N$ is the number of markers. This makes the full permutation approach computationally prohibitive for the newer arrays that contain tens of thousands markers and highlights the …

Slides: Climate Change & The Ecological Resources Of The West, Chris Field

Climate Change and the Future of the American West: Exploring the Legal and Policy Dimensions (Summer Conference, June 7-9)

Presenter: Chris Field, Director, Department of Global Ecology, Carnegie Institution of Washington, DC.

39 slides.

Contains references.

Agenda: Climate Change And The Future Of The American West: Exploring The Legal And Policy Dimensions, University Of Colorado Boulder. Natural Resources Law Center

Climate Change and the Future of the American West: Exploring the Legal and Policy Dimensions (Summer Conference, June 7-9)

Sponsors: The William and Flora Hewlett Foundation; BP America; Holland & Hart; Patrick, Miller & Krope, P.C.; The Rocky Mountain Mineral Law Foundation, Rocky Mountain Natural Resource Center of the National Wildlife Federation, Western Water Assessment.

Exploring the legal and political dimensions that climate change will bring to the American West will be the focus of the CU-Boulder Natural Resources Law Center's 27th Annual Summer Conference.

Titled "Climate Change and the Future of the American West: Exploring the Legal and Policy Dimensions," the conference will be held June 7-9 at the Fleming Law Building on the University of Colorado at …

Slides: Weather And Climate Extremes In A Future Warmer Climate, Gerald A. Meehl

Climate Change and the Future of the American West: Exploring the Legal and Policy Dimensions (Summer Conference, June 7-9)

Presenter: Gerald A. Meehl, Senior Scientist, National Center for Atmospheric Research.

16 slides.

Slides: The Real Biofuel Cycles And The Earth, Biofuels, And Reality, Tad W. Patzek

Climate Change and the Future of the American West: Exploring the Legal and Policy Dimensions (Summer Conference, June 7-9)

Presenter: Tad W. Patzek, Professor of Petroleum Engineering, University of California at Berkeley, Berkeley, CA

2 pages and 29 slides.

Contains footnotes.

The Earth, Energy, And Agriculture, Tad W. Patzek

Climate Change and the Future of the American West: Exploring the Legal and Policy Dimensions (Summer Conference, June 7-9)

Presenter: Tad W. Patzek, Professor of Petroleum Engineering, University of California at Berkeley, Berkeley, CA.

13 pages (includes some color illustrations).

Contains references.

Faculty Evaluate Resources And Services, Winter 2006, Eastern Michigan University Library

Library Assessment Reports

No abstract provided.

Cold Event In The South Atlantic Bight During Summer Of 2003: Anomalous Hydrographic And Atmospheric Conditions, Alfredo Aretxabaleta, James R. Nelson, Jack O. Blanton, Harvey E. Seim, Francisco E. Werner, John M. Bane, Robert H. Weisberg

Marine Science Faculty Publications

Unusually cold seawater temperatures were observed along much of the U.S. eastern seaboard during the summer of 2003. In this study, hydrographic and atmospheric observations from spring through summer were analyzed to track the evolution of the cold water event in the South Atlantic Bight (SAB) and investigate links to various forcing mechanisms. The hydrographic observations included 13 cross‐shelf transects over the central region of the SAB, surface temperature time series from several NDBC stations, and bottom temperatures from a mid shelf mooring. Atmospheric data were obtained from NDBC stations. Additional data included water level from NOS stations and river …

The Effect Of Physiological Cyclic Stretch On The Cell Morphology, Cell Orientation And Protein Expression Of Endothelial Cells, V. Barron, Claire Brougham, K. Coghlan, C. Stenson-Cox, D. O'Mahoney, P.E. Mchugh

Articles

In vivo, endothelial cells are constantly exposed to pulsatile shear and tensile stresses. The main aim of this study was to design and build a physiological simulator, which reproduced homogenous strain profiles of the tensile strain experienced in vivo, and to investigate the effect of this cyclic tensile strain on the cell morphology, cell orientation and protein expression of endothelial cells. The biological response of human umbilical vein endothelial cells to a uniaxial cyclic stretch, in this newly developed simulator, was examined experimentally using immunohistostaining and confocal imaging and it was

found that the cells elongated and oriented at 58.9± …

Ke Alakai, Vol. 75, No. 03 (2006-06-07), Brigham Young University Hawaii

Ke Alaka'i

No abstract provided.

Wsu Board Of Trustees Meeting Minutes, June 7-8, 2006

Board of Trustees Minutes

Minutes from the Wright State University Board of Trustees Meeting held on June 7-8, 2006.

Fabrication Of Polymeric Microfluidic Devices For Protein Analysis, Jikun Liu

Theses and Dissertations

2-Bromoisobutyryl bromide was immobilized on poly(methyl methacrylate) (PMMA) substrates activated using an oxygen plasma. Atom-transfer radical polymerization was then performed to graft poly(ethylene glycol) (PEG) on the PMMA surface. PMMA micro capillary electrophoresis (µCE) devices made with the covalently modified surfaces exhibited substantially reduced electroosmotic flow and nonspecific adsorption of proteins. Both column efficiency and migration time reproducibility were one order of magnitude better with derivatized PMMA µCE devices compared to untreated versions. Fast, reproducible, and efficient separations of proteins and peptides were demonstrated using the PEG-grafted PMMA µCE chips. All analyses were completed in less than 60 seconds, and …