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2006

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Analysing Survey Data With Incomplete Responses By Using A Method Based On Empirical Likelihood, Denis H. Y. Leung, Jing Qin May 2006

Analysing Survey Data With Incomplete Responses By Using A Method Based On Empirical Likelihood, Denis H. Y. Leung, Jing Qin

Research Collection School Of Economics

In many surveys, missing response is a common problem. As an example, Zahner, Jacobs, Freeman and Trainor analysed data from a study of child psychopathology in the State of Connecticut, USA. In that study, the response variable, psychopathology, was inferred from questions that were addressed to teachers of the children and was subject to a high level of missingness. However, the missing responses were supplemented by surrogate information that was provided by the parents and/or the primary care providers of the children. In such a situation, it is conceivable that the supplemental information can be used to recover some of …

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Staphylococcus Aureus Escapes More Efficiently From The Phagosome Of A Cystic Fibrosis Bronchial Epithelial Cell Line Than From Its Normal Counterpart, Todd M. Jarry, Ambrose L. Cheung May 2006

Staphylococcus Aureus Escapes More Efficiently From The Phagosome Of A Cystic Fibrosis Bronchial Epithelial Cell Line Than From Its Normal Counterpart, Todd M. Jarry, Ambrose L. Cheung

Dartmouth Scholarship

Staphylococcus aureus is frequently the initial bacterium isolated from young cystic fibrosis (CF) patients, and yet its role in CF disease progression has not been determined. Recent data from our lab demonstrates that S. aureus can invade and replicate within the CF tracheal epithelial cell line (CFT-1). Here we describe the finding that the fate of internalized S. aureus in CFT-1 cells differs from its complemented counterpart (LCFSN). S. aureus strain RN6390 was able to replicate within the mutant CFT-1 cells after invasion but not in the complemented LCFSN cells. At 1 h postinvasion, S. aureus containing vesicles within both …

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Folate-Targeted Immunotherapy Effectively Treats Established Adjuvant And Collagen-Induced Arthritis, Chrystal M. Paulos, Bindu Varghese, William R. Widmer, Gert J. Breur, Erina Vlashi, Philip S. Low Apr 2006

Folate-Targeted Immunotherapy Effectively Treats Established Adjuvant And Collagen-Induced Arthritis, Chrystal M. Paulos, Bindu Varghese, William R. Widmer, Gert J. Breur, Erina Vlashi, Philip S. Low

Department of Chemistry Faculty Publications

Activated macrophages express a cell surface receptor for the vitamin folic acid. Because this receptor is inaccessible or not measurably expressed on other normal cells, folic acid has been recently exploited to selectively deliver attached radio-emitters to sites of activated macrophage accumulation, allowing scintigraphic imaging of inflamed joints and organs of arthritic rats. We demonstrate here that folate-linked haptens can also be targeted to activated macrophages, decorating their cell surfaces with highly immunogenic molecules. Under conditions in which the rodent has already been immunized against keyhole limpet hemocyanine-(fluorescein isothiocyanate) FITC, activated macrophages are eliminated. Administration of folate-FITC conjugates to rodents …

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Crossing The Immunological Barrier, Farrah Qazi Apr 2006

Crossing The Immunological Barrier, Farrah Qazi

ExpressO

No abstract provided.

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Apply For Summer Scholars, University Relations Apr 2006

Apply For Summer Scholars, University Relations

Campus News Archive

It's not too early to start thinking about summer. More specifically, if you're a high school sophomore or junior ranking in the top 20 percent of your class, it's time to think about attending the Summer Scholars program at UMM.

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Lack Of Il-15 Results In The Suboptimal Priming Of Cd4+ T Cell Response Against An Intracellular Parasite, Crescent L. Combe, Magali M. Moretto, Joseph D. Schwartzman, Jason P. Gigley, David J. Bzik, Imtiaz A. Khan Apr 2006

Lack Of Il-15 Results In The Suboptimal Priming Of Cd4+ T Cell Response Against An Intracellular Parasite, Crescent L. Combe, Magali M. Moretto, Joseph D. Schwartzman, Jason P. Gigley, David J. Bzik, Imtiaz A. Khan

Dartmouth Scholarship

IFN-gamma-producing CD4+ T cells, although important for protection against acute Toxoplasma gondii infection, can cause gut pathology, which may prove to be detrimental for host survival. Here we show that mice lacking IL-15 gene develop a down-regulated IFN-gamma-producing CD4+ T cell response against the parasite, which leads to a reduction in gut necrosis and increased level of survival against infection. Moreover, transfer of immune CD4+ T cells from WT to IL-15-/- mice reversed inhibition of gut pathology and caused mortality equivalent to levels of parental WT mice. Down-regulated CD4+ T cell response in the absence of IL-15, manifested as reduced …

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Washington University Record, April 21, 2006 Apr 2006

Washington University Record, April 21, 2006

Washington University Record

No abstract provided.

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Advances In Teaching & Learning Day Abstracts 2006, Cynthia L. Phelps Apr 2006

Advances In Teaching & Learning Day Abstracts 2006, Cynthia L. Phelps

Advances in Teaching and Learning Day Abstracts

Proceedings of the Advances in Teaching & Learning Day Regional Conference held at The University of Texas Health Science Center at Houston in 2006.

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Crow's Nest, April 19, 2006, Crow's Nest Staff Apr 2006

Crow's Nest, April 19, 2006, Crow's Nest Staff

Crow's Nest

The April 19, 2006, issue of the Crow's Nest.

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Bard Observer, Vol. 20, No. 12 (April 18, 2006), Bard College Apr 2006

Bard Observer, Vol. 20, No. 12 (April 18, 2006), Bard College

Bard Observer - All Issues (1956 - Current)

No abstract provided.

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April 17, 2006 Reporter, University Of Alabama At Birmingham Apr 2006

April 17, 2006 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

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Alaska's $5 Billion Health Care Bill - Who's Paying?, Scott Goldsmith, Mark Foster Apr 2006

Alaska's $5 Billion Health Care Bill - Who's Paying?, Scott Goldsmith, Mark Foster

ISER Reports

Spending for health care in Alaska topped $5 billion in 2005. Just how big is $5 billion? It is, for perspective, one-third the value of North Slope oil exports in 2005—a year of high oil prices. It’s nearly one-sixth the value of everything Alaska’s economy produced last year. In 1991, health-care spending in Alaska was about $1.6 billion. Even after we take population growth into account, spending for health care increased 176% per Alaskan in 15 years. These soaring costs are taking a growing share of family and government budgets, increasing labor costs, and putting businesses at a competitive disadvantage.

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Understanding Alaska: People, Economy, And Resources, Mark Foster, Pamela Cravez, Terrence Cole Apr 2006

Understanding Alaska: People, Economy, And Resources, Mark Foster, Pamela Cravez, Terrence Cole

ISER Reports

Understanding Alaska is a special series of studies by the Institute of Social and Economic Research (ISER), to examine economic development issues and help Alaskans understand how their economy works. The studies began in 2001, and here we highlight some of the work so far. The University of Alaska Foundation has provided most of the funding for Understanding Alaska which examines how Alaska’s economy works, why it’s different from those in other states, and how Alaska’s unique circumstances affect economic development. This publication divides Understanding Alaska research into three categories: People, Economy, and Fisheries. At the end of each section …

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Electronic Health Records - What Data Can Be Automatically Collected From Laboratory Instruments And Bedside Monitors?, Reed Gardner Apr 2006

Electronic Health Records - What Data Can Be Automatically Collected From Laboratory Instruments And Bedside Monitors?, Reed Gardner

Historical and Administrative Collection

Electronic Health Records (EHR) are becoming more common in today\'s modern health care systems. However, gathering key clinical data by nurses, pharmacists and physicians in an accurate, timely, and efficient manner is still problematic. However, just as with banking and the Internet, there are "automated" methods that help solve these problems. This presentation discusses these methods and shows how they are used in the clinical setting.

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Agent-Based Modeling Of The Bristol Bay Drift Gillnet Salmon Fishery, Brandon Chasco, Gunnar Knapp, Ray Hilborn Apr 2006

Agent-Based Modeling Of The Bristol Bay Drift Gillnet Salmon Fishery, Brandon Chasco, Gunnar Knapp, Ray Hilborn

ISER Reports

Alaska’s Bristol Bay sockeye salmon fishery is the world’s largest fishery for this species. Between 1980 and 2005, annual catches averaged 24 million fish, with an annual average ex-vessel value of US$165 million. Historically, the Bristol Bay sockeye salmon fishery has accounted for 20-40% of the total value of Alaska salmon fisheries. Similar to most other Alaska salmon fisheries, Bristol Bay fisheries are managed to achieve escapement goals for several major river systems flowing into Bristol Bay. Fish- ing is allowed during period “openings” over the season to catch returning salmon surplus to escapement goals. In general, the current management …

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Washington University Record, April 14, 2006 Apr 2006

Washington University Record, April 14, 2006

Washington University Record

No abstract provided.

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Super Learning: An Application To Prediction Of Hiv-1 Drug Susceptibility, Sandra E. Sinisi, Maya L. Petersen, Mark J. Van Der Laan Apr 2006

Super Learning: An Application To Prediction Of Hiv-1 Drug Susceptibility, Sandra E. Sinisi, Maya L. Petersen, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

Many statistical methods exist that can be used to learn a predictor based on observed data. Examples include decision trees, neural networks, support vector regression, least angle regression, Logic Regression, and the Deletion/Substitution/Addition algorithm. The optimal algorithm for prediction will vary depending on the underlying data-generating distribution. In this article, we introduce a "super learner," a prediction algorithm that applies any set of candidate learners and uses cross-validation to select among them. Theory shows that asymptotically the super learner performs essentially as well or better than any of the candidate learners. We briefly present the theory behind the super learner, …

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Illinois State University Report, April 13, 2006, Illinois State University Apr 2006

Illinois State University Report, April 13, 2006, Illinois State University

Illinois State University Report (1966-2012)

Illinois State University bi-weekly employee newsletter.

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Spectrophotometric System And Method For The Identification And Characterization Of A Particle In A Bodily Fluid, Luis H. Garcia-Rubio, Catalina E. Alupoaei, Willard Harris, Alfredo Peguero, Edward P. Cutolo, German Felix Leparc Apr 2006

Spectrophotometric System And Method For The Identification And Characterization Of A Particle In A Bodily Fluid, Luis H. Garcia-Rubio, Catalina E. Alupoaei, Willard Harris, Alfredo Peguero, Edward P. Cutolo, German Felix Leparc

USF Patents

The present invention provides a method and apparatus for the detection of an infectious disease or disorder in a fluid, such as a mammalian blood sample, the detection of a specific protein in a urine sample, or the detection of a particle in a plasma. The identification of the particles of interest is enable by taking a transmission spectrum of a test sample in at least a portion of the ultraviolet, visible, near-infrared portion of the spectrum and comparing the spectrum with a standard sample spectrum. From the comparison it is then determined whether the fluid from the test sample …

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Methods For Preventing And Treating Cancer Using N-Thiolated Β-Lactam Compounds And Analogs Thereof, Q. Ping Dou, Edward Turos, David M. Smith Apr 2006

Methods For Preventing And Treating Cancer Using N-Thiolated Β-Lactam Compounds And Analogs Thereof, Q. Ping Dou, Edward Turos, David M. Smith

USF Patents

The subject invention concerns N-thiolated β-lactam compounds of formula A, wherein R1 is a hydrocarbon group having 1–8 carbon atoms; R3 is an organothio group; and R4 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, cycloalkenyl, or heterocycloalkenyl, and analogs and pharmaceutically acceptable salts, esters and amides thereof. The subject invention also concerns methods for inducing tumor cell death or inhibiting tumor cell proliferation, and methods for inducing DNA damage, inhibiting DNA replication, activating p38 MAP kinase, or activating caspase cascade activation, or releasing cytochrome C from mitochondria into the cytoplasm in a tumor cell. Methods for treating cancer using …

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The Latent Membrane Protein 1 Of Epstein-Barr Virus (Ebv) Primes Ebv Latency Cells For Type I Interferon Production, Dongsheng Xu, Kristen Brumm, Luwen Zhang Apr 2006

The Latent Membrane Protein 1 Of Epstein-Barr Virus (Ebv) Primes Ebv Latency Cells For Type I Interferon Production, Dongsheng Xu, Kristen Brumm, Luwen Zhang

Nebraska Center for Virology: Faculty Publications

Epstein-Barr virus (EBV) latency has been associated with a variety of human cancers. Latent membrane protein 1 (LMP-1) is one of the key viral proteins required for transformation of primary B cells in vitro and establishment of EBV latency. We have previously shown that LMP-1 induces the expression of several interferon (IFN)-stimulated genes and has antiviral effect (Zhang, J., Das, S. C., Kotalik, C., Pattnaik, A. K., and Zhang, L. (2004) J. Biol. Chem. 279, 46335–46342). In this report, a novel mechanism related to the antiviral effect of LMP-1 is identified. We show that EBV type III latency cells, in …

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Washington University Record, April 7, 2006 Apr 2006

Washington University Record, April 7, 2006

Washington University Record

No abstract provided.

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Observer, Central Washington University Apr 2006

Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for April 6, 2006

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The Mucilage Of Opuntia Ficus Indica: A Natural, Sustainable, And Viable Water Treatment Technology For Use In Rural Mexico For Reducing Turbidity And Arsenic Contamination In Drinking Water, Kevin Andrew Young Apr 2006

The Mucilage Of Opuntia Ficus Indica: A Natural, Sustainable, And Viable Water Treatment Technology For Use In Rural Mexico For Reducing Turbidity And Arsenic Contamination In Drinking Water, Kevin Andrew Young

USF Tampa Graduate Theses and Dissertations

The use of natural environmentally benign agents in the treatment of drinking water is rapidly gaining interest due to their inherently renewable character and low toxicity. We show that the common Mexican cactus produces a gum-like substance, cactus mucilage, which shows excellent flocculating abilities and is an economically viable alternative for low-income communities. Cactus mucilage is a neutral mixture of approximately 55 high-molecular weight sugar residues composed basically of arabinose, galactose, rhamnose, xylose, and galacturonic acid. We show how this natural product was characterized for its use as a flocculating agent. Our results show the mucilage efficiency for reducing arsenic …

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Research Conference Hits Um April 8, University Of Montana--Missoula. Office Of University Relations Apr 2006

Research Conference Hits Um April 8, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

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Um Grant To Study Pollution Effects On Human Immune System, University Of Montana--Missoula. Office Of University Relations Apr 2006

Um Grant To Study Pollution Effects On Human Immune System, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

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Flight Physician - April, 2006, Civil Aviation Medical Association Apr 2006

Flight Physician - April, 2006, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A sixteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

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Idcr: Infectious Diseases In Corrections Report, Vol. 9 No. 4, Infectious Diseases In Corrections Apr 2006

Idcr: Infectious Diseases In Corrections Report, Vol. 9 No. 4, Infectious Diseases In Corrections

Infectious Diseases in Corrections Report (IDCR)

No abstract provided.

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Wsu Research News, Spring 2006, Office Of Research And Sponsored Programs, Wright State University Apr 2006

Wsu Research News, Spring 2006, Office Of Research And Sponsored Programs, Wright State University

WSU Research News

A twelve page newsletter of the WSU Research News. The WSU Research News was published monthly beginning in June of 1968 and issued by the Office of Research Development. This newsletter was created to provide information to the WSU faculty about the availability of outside funds for research and educational programs, new developments that may affect availability of funds, and general information on research and educational activities at Wright State University.

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Intellectual Property Management Strategies To Accelerate The Development And Access Of Vaccines And Diagnostics: Case Studies On Pandemic Influenza, Malaria And Sars, Anatole Krattiger, Stanley P. Kowalski, Robert Eiss, Anthony Taubman Apr 2006

Intellectual Property Management Strategies To Accelerate The Development And Access Of Vaccines And Diagnostics: Case Studies On Pandemic Influenza, Malaria And Sars, Anatole Krattiger, Stanley P. Kowalski, Robert Eiss, Anthony Taubman

Law Faculty Scholarship

Achieving global access to vaccines, diagnostics, and pharmaceuticals remains a challenge. Throughout the developing world, intellectual property (IP) constraints complicate access to critically essential medical technologies and products. Vaccines for malaria and pandemic strains of influenza, as well as diagnostic and vaccine technologies for SARS, are not only relevant to global public health but are particularly critical to the needs of developing countries. A global access solution is urgently needed. This article offers a timely case‐by‐case analysis of preliminary patent landscape surveys and formulates options via patent pools and other forms of creative IP management to accelerate development and access. …

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