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2006

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State Of Being, Anne Bradshaw Jan 2006

State Of Being, Anne Bradshaw

Theses and Dissertations

My work speaks to the processes of adaptation and assimilation, phenomena that explain the way in which we transform life experience and incorporate the effects of such experience into the daily workings of our psyche. To this extent my work is a self-analysis, an autobiographical reckoning, a non-verbal representation of collective experiences rendered in forms upon which images are spontaneously drawn or painted with fiber. The process of making art as a means of accessing creative instincts is a manifestation of the way in which I experience life. Adapting and assimilating to our human condition is an art, a form …

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Machismo As A Determinant For Hiv/Std Risk Behavior Among Latino Msm, Jacqueline L. Sears Jan 2006

Machismo As A Determinant For Hiv/Std Risk Behavior Among Latino Msm, Jacqueline L. Sears

Theses and Dissertations

Objective: Male-to-male sexual contact is the most common mode of transmission for HIV among Latino men. Psychosocial factors such as machismo, homophobic discrimination, and internalized homophobia have been hypothesized to greatly impact sexual behaviors among Latinos. However, studies investigating the relationship between these psychosocial factors and risky sexual behaviors are limited. This study examined the impact of machismo on risky sexual behaviors among Latino Male who have Sex with Men (MSM).Methods: This study utilized data collected from 254 Latino MSM in 1999 from selected cities within Virginia. The analysis focused on respondent demographic characteristics, psychosocial factors, acculturation, and sexual risky …

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Supportive And Unsupportive Responses From Parents As Moderators Of The Relationship Between Stressful Events And Negative Outcomes In Adolescents, Karen A. Muehl Jan 2006

Supportive And Unsupportive Responses From Parents As Moderators Of The Relationship Between Stressful Events And Negative Outcomes In Adolescents, Karen A. Muehl

Theses and Dissertations

The objective of this study was to investigate the relationship between stressful events in adolescents and negative outcomes of substance use, depressive symptoms, and anxiety symptoms. Parental support and unsupportive parental responses were examined as moderators of this relationship. The research design was cross-sectional, and self-report data were collected from 100 adolescents in the 8th and 9th grades. As hypothesized, significant positive associations were found between perceived stressors and each of the three negative outcomes, as well as between unsupportive parental responses and the outcomes. Also consistent with hypotheses, and previous literature, was the finding of a significant inverse association …

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Characterization Of Vancomycin Resistance In Staphylococcus Aureus, Paige Mccarthy Fox Jan 2006

Characterization Of Vancomycin Resistance In Staphylococcus Aureus, Paige Mccarthy Fox

Theses and Dissertations

In the past decade, Staphylococcus aureus has developed two distinct vancomycin resistance mechanisms. First, the bacterium is capable of generating a thickened, poorly crosslinked cell wall that creates false targets. These targets cause vancomycin to bind at the periphery of the thickened peptidoglycan, allowing normal cell wall formation to continue at the cell membrane. Second, S. aureus has acquired genes from Enterococcus that encode an alternative stem peptide. The genes, known as van genes, alter the target of vancomycin, rendering vancomycin treatment ineffectual.In this work, we attempted to further characterize both mechanisms of vancomycin resistance. First, a potential link between …

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A Longitudinal Investigation Of Cognitive Predictors Of Self-Care Behaviors In Youth With Type I Diabetes, Michelle Marie Greene Jan 2006

A Longitudinal Investigation Of Cognitive Predictors Of Self-Care Behaviors In Youth With Type I Diabetes, Michelle Marie Greene

Theses and Dissertations

Cross-sectional research of youth with type I diabetes has demonstrated that rote and working memory predict blood glucose monitoring (BGM) and carbohydrate consumption, respectively; however, to date, no longitudinal follow-up studies exist. Rote and working memory subtests from well-standardized memory measures, along with a problem-solving and executive functioning measures were administered to 118 youth with type I diabetes, aged 9-16 in two waves of data collection (mean interval = 2.07 years). Diabetes care behaviors were assessed through the 24-hour Diabetes Interview. This study was the first to document longitudinal prediction of BGM by rote memory and fat consumption by working …

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Immunological And Molecular Analyses Of The Borrelia Burgdorferi Ospf Protein Family F, Emily Tran Jan 2006

Immunological And Molecular Analyses Of The Borrelia Burgdorferi Ospf Protein Family F, Emily Tran

Theses and Dissertations

In North America, Borrelia burgdorferi is the primary causative agent of Lymedisease which is a growing health concern. The ability of B. burgdorferi to maintain chronic infection indicates that they are capable of immune evasion. A distinguishing characteristic of B. burgdorferi is the large number of sequences encoding predicted or known lipoproteins, including outer surface protein F (OspF). This study analyzes the specificity of the humoral immune response to B. burgdorferi B3 IMI OspF proteins during murine and human infection. Immunoblot analyses revealed a temporal expression of OspF proteins during infection and mapped the immunodominant epitopes which lie within the …

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Association Between Smoking, Chemical Exposure And Hearing Loss In An Occupational Setting, Darlene W. Olive Jan 2006

Association Between Smoking, Chemical Exposure And Hearing Loss In An Occupational Setting, Darlene W. Olive

Theses and Dissertations

Objective: Twenty-two million Americans or roughly 8% of the population are hearing impaired. This affects more than just the ability for one to hear. In the last three decades, younger Americans have shown a sharp increase in hearing impairment. Hearing loss affects social and emotional well being and thus has the ability to decrease one's quality of life. This study was designed to examine the association between smoking, workplace chemical exposure, and hearing loss.Methods: This cross-sectional population-based study was conducted in an occupational health clinic setting in Virginia. The study population consisted of employees from local businesses who visited the …

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A Gis And Remote Sensing Based Analysis Of Impervious Surface Influences On Bald Eagle (Haliaeetus Leucocephalus) Nest Presence In The Virginia Portion Of The Chesapeake Bay, Jennifer M. Ciminelli Jan 2006

A Gis And Remote Sensing Based Analysis Of Impervious Surface Influences On Bald Eagle (Haliaeetus Leucocephalus) Nest Presence In The Virginia Portion Of The Chesapeake Bay, Jennifer M. Ciminelli

Theses and Dissertations

GIS (Geographic Information Systems) and remote sensing techniques were used to predict relationships between bald eagle nest presences and land type, distance to land type and impervious surface cover area. Data plots revealed bald eagle nest presence decreases in response to an increase in area of bareland; increases with an increase in area of forested land; decreases with an increase in distance (m) to shoreline, and decreases in response to an increase in area of impervious surfaces. Logistic regression models identified impervious surfaces as an indicator for bald eagle nest presence (P 24% as unsuitable. Unsuitable area covered 17.82% of …

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A Needs Assessment For Annual Physical Examination For Selected Richmond Public School Children, Aimee Gibbs Jan 2006

A Needs Assessment For Annual Physical Examination For Selected Richmond Public School Children, Aimee Gibbs

Theses and Dissertations

Introduction: The following risk factors have found to be associated with inadequate health care and have been found to affect the well-being of children: racial or ethnic minority, poverty status, median family income, family structure of household, maternal education level, and parental employment status. Also, there has found to be health indicators including, teen pregnancy, asthma hospitalization, and lead poisoning cases that affect the well-being of a child and are associated with the presence of these risk factors in a population. Objectives: The objectives of this study is to (1) compare the presence of risk factors and health indicators in …

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Predictors Of Primary Elective Cesarean Delivery Among Apparently Healthy Pregnant Women In Virginia, Brooke W. Rossheim Jan 2006

Predictors Of Primary Elective Cesarean Delivery Among Apparently Healthy Pregnant Women In Virginia, Brooke W. Rossheim

Theses and Dissertations

Objectives. The purpose of this cross-sectional study was to evaluate whether certain maternal variables were associated with the performance of a primary cesarean delivery rather than a spontaneous vaginal delivery among apparently healthy pregnant women in the Commonwealth of Virginia.Methods. This study utilized the 2004 Virginia Statistics File for Live Births which contained 103,830 records. From this dataset, the following groups of women were excluded: multiparous women, women who had had a previous delivery by any method, women with medical and obstetric problems, women with any labor and delivery complications, women with premature births and women with multiple gestations. The …

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Influence Of Organizational, Operational, Financial Andenvironmental Factors On Hospitals' Adoption Of Computerized Physician Order Entry Systems For Improving Patient Safety: A Resource Dependence Approach, Imre Solti Jan 2006

Influence Of Organizational, Operational, Financial Andenvironmental Factors On Hospitals' Adoption Of Computerized Physician Order Entry Systems For Improving Patient Safety: A Resource Dependence Approach, Imre Solti

Theses and Dissertations

This study examines specific organizational, operational, financial and environmental characteristics to identify factors that are associated with increased likelihood of hospitals' CPOE adoption decision in six rollout regions of the Leapfrog initiatives.Resource dependence theory provides theoretical basis for the study. The study is retrospective observational in design. Individual hospitals are the unit of analysis. The Leapfrog Group's 2002-survey collection serves the primary data source. Univariate statistical methods along with bivariate and ordinal logistic regression models are used to analyze the data. The models provided support for multiple hypotheses for both the adoption and early adoption decisions of study hospitals. The …

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Small Molecules Binding To Serpins, Junaid Afridi Jan 2006

Small Molecules Binding To Serpins, Junaid Afridi

Theses and Dissertations

Serpins are a unique breed of proteins due to their enzymatic mechanism. Two systems were closely monitored during fluorescent binding studies, the ACT-CHY along with the AT:TRY interaction. Four different conformational variants of each system were studied including the native, cleaved, latent and complex forms. Three different fluorescent dyes were used to identify the conformations including ANS, TNS, and bis-ANS. SI studies and protease assays utilizing both Suc-AAPF-pNA and L-BAPNA were instrumental in determining conformations along with gel electrophoresis studies. The hydrophobic dyes bound to the different serpins with varying KD and ΔFmax due to structural variations among the conformers …

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The Role Of Gonadal Hormones On Opioid Receptor Protein Density In Arthritic Rats, Matthew Kren Jan 2006

The Role Of Gonadal Hormones On Opioid Receptor Protein Density In Arthritic Rats, Matthew Kren

Theses and Dissertations

The majority of research on the endogenous opioid system has focused on various pain assays and the efficacy of different opioid agonists. However, minimal attention has been focused on the effects of gonadal hormones and their impact on the opioid peptide system. The present study was designed to determine the effects of modulation of gonadal hormones on the opioid receptor protein levels in Complete Freund's Adjuvant (CFA)-treated arthritic and non-arthritic male and female Lewis rats. Midbrain and spinal cord tissues were collected for comparison of the μ, δ, and κ receptor protein levels in arthritic and non-arthritic animals. Male gonadectomy …

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Everyday Haunting, Thomas John Condon Jr. Jan 2006

Everyday Haunting, Thomas John Condon Jr.

Theses and Dissertations

This document outlines a journey of self-exploration, discovery, construction and destruction. It is a story of learning, a testament to impermanence, and a proposal for possibility. The words and work contained in this document are exclusive to the thoughts and actions of one man that hopes to share with others.

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The Relationship Between Eating Disordered Behavior And Smoking In Black And White College Females, Sarah Elizabeth Trace Jan 2006

The Relationship Between Eating Disordered Behavior And Smoking In Black And White College Females, Sarah Elizabeth Trace

Theses and Dissertations

Both eating disorders and smoking are significant problems for Black and White college women. Additionally, these two negative health behaviors frequently co-occur. This study aimed to investigate the relationship between these health behaviors using a multivariate model. Two models, one for full and one for partial mediation, were tested using Structural Equation Modeling. The Model for full mediation tested whether the relationship among general distress and smoking are fully mediated by body dissatisfaction, restraint, and binge eating. The model for partial mediation hypothesized that the relationships among general distress, and smoking are mediated by body dissatisfaction, restraint, and binge eating. …

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The Influence Of Physical Activity And Television On The Intention And Self-Efficacy To Engage In Health-Enhancing Behaviors, Ian Joseph Wallace Jan 2006

The Influence Of Physical Activity And Television On The Intention And Self-Efficacy To Engage In Health-Enhancing Behaviors, Ian Joseph Wallace

Theses and Dissertations

Cancer and heart disease account for the largest proportion of morbidity and mortality among all adult diseases in the United States. Research has focused on identifying causal risk factors among adolescents. However, theories of health behavior change also stress the intermediary factors of intention and efficacy for effective behavior change. Existing research supports the potential of physical activity (PA), particularly learned through the domains of exercise and sport, as a means to developing these necessary skills (Danish, Petitpas, & Hale, 1993). The current investigation examined the influence of PA and television watching (TV) on intentions and efficacy to engage in …

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The Effect Of Advertising On Attitudes Toward Tobacco Use And Decisions About Smoking Among Virginia Adolescents, John Rosser Matthews Iii Jan 2006

The Effect Of Advertising On Attitudes Toward Tobacco Use And Decisions About Smoking Among Virginia Adolescents, John Rosser Matthews Iii

Theses and Dissertations

Purpose: This study seeks to determine 1) whether the type of advertising exposure is associated with adolescent health perceptions of tobacco use, and 2) whether the type of media exposure is associated with initiation plans (non-smokers) or quitting plans (smokers). Methods: This was a cross-sectional survey of middle school students (n=l1,128).Psychosocial variables were knowledge of the risks of tobacco use (range: 3-15) and benefits of being tobacco free (range: 7-35) with higher scores indicating greater understanding. Intentions to quit or initiate were construed as binary variables. Exposure variables were tobacco advertisements or anti-tobacco media messages. Covariates were gender, race, grade …

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Characterization Of The Tcof1 Gene Using A Neuroblastoma Cell Line And A Mouse Model, Lin Li Jan 2006

Characterization Of The Tcof1 Gene Using A Neuroblastoma Cell Line And A Mouse Model, Lin Li

Theses and Dissertations

Treacher Collins syndrome (TCS) is an autosomal dominant craniofacial development disorder and is caused by mutations in the TCOF1 gene. The TCOFl protein treacle is a nucleolar protein and may function in ribosome biogenesis.Previously, we identified downstream candidate genes using microarray analysis after manipulating Tcofl levels in a murine neuroblastoma (NB) cell line. The list of genes includes cell cycle genes as well as the transcription factors Cnbp and Tbx2, which are known to affect the cell cycle through the c-myc and p19-Mdm2-p53-p21 pathways respectively. To further characterize the cellular effects of Tcofl, stably transfected NB cell lines with overexpression …

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From Below Table Mesa, Cynthia Grier Lotze Jan 2006

From Below Table Mesa, Cynthia Grier Lotze

Theses and Dissertations

I lived in Boulder, Colorado longenough, and I dreamed low-resolutiondreams, sharp only at eyes and slow movinghands.Kate's hair was a cloud of insurrectionon the tarmac, then I would watch the hoursmelt off the wings of her plane as eachstate became not-Tennessee, not-Kansas.I wanted to meet her in the air; Icould will this without a plane, with sadness,with need, I would enter the plane in flightand I would say, "Kate, take me home," and shewould turn the plane around. Everythingwould become not-Colorado, not thisstaticky dream, hard breath miles up from the sea.

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Conceptualizing Hoarding Behavior Among Elderly Women: A Mixed-Methods Approach, Susan Jan Murdock Jan 2006

Conceptualizing Hoarding Behavior Among Elderly Women: A Mixed-Methods Approach, Susan Jan Murdock

Theses and Dissertations

Hoarding in the community involves substantial cluttering and impaired functioning, often exposing the hoarder to extensive health and safety risks. This research, based on Functionalism social theory, explores the three elements of hoarding—relentless acquisition, intense possessiveness of objects, and a reluctance to discard possessions—as a sociocultural phenomenon. The mixed methods methodology entailed a quantitative study involving a survey completed by 134 adult protective services workers throughout Virginia and a qualitative study of five randomly-selected adult protective services workers who volunteered for in-depth interviews.Findings revealed that adult protective services workers come in contact with very severe cases of hoarding, with over …

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C - Reactive Protein, Coronary Heart Disease And Ischemic Stroke In The Elderly: The Cardiovascular Health Study, Xia Li Jan 2006

C - Reactive Protein, Coronary Heart Disease And Ischemic Stroke In The Elderly: The Cardiovascular Health Study, Xia Li

Theses and Dissertations

Background: C-reactive protein (CRP) has been associated with increased risk of coronary heart disease (CHD) and stroke, but much of the research had focused on middle-aged populations with, limited prospective, population-based, longitudinal data. In this study, we examined data from an elderly population and described the distribution of CRP concentrations and the prevalence of elevated CRP levels (>3 mg/l), examined the association between CRP levels and incidence of CHD or ischemic stroke, and assessed the potential interaction of CRP with sex or race on the incidence of CHD or ischemic stroke.Methods: Baseline CRP levels were measured in a cohort …

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Urban Growth And Segregation In The Roanoke, Virginia, Metropolis: The Effects Of Low-Density Development On Low-Income Populations And Racial Minorities, Freed Etienne Jan 2006

Urban Growth And Segregation In The Roanoke, Virginia, Metropolis: The Effects Of Low-Density Development On Low-Income Populations And Racial Minorities, Freed Etienne

Theses and Dissertations

This dissertation examines urban growth patterns in the Roanoke, Virginia, metropolis. It draws on the literature of contemporary human ecology and social area analysis to examine the effects of low-density development on low-income populations and racial minorities. The continuous spread of residential development beyond the boundaries of the central city and older suburbs into more distant, once rural areas is segregating the metropolitan area by race and income. Since the prominence of the so-called "Chicago School" of urban sociology (1913-1940), contemporary urban sociologists have outlined theories and methods to examine how American urban areas have changed and why. This dissertation …

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Meta-Analysis Of Open Vs Closed Surgery Of Mandibular Condyle Fractures, Marcy Lauren Nussbaum Jan 2006

Meta-Analysis Of Open Vs Closed Surgery Of Mandibular Condyle Fractures, Marcy Lauren Nussbaum

Theses and Dissertations

A review of the literature reveals a difference of opinion regarding whether open or closed reduction of condylar fractures produces the best results. It would be beneficial to critically analyze past studies that have directly compared the two methods in an attempt to answer this question. A Medline search for articles using the key words 'mandibular condyle fractures' and 'mandibular condyle fractures surgery' was performed. The articles chosen for the meta-analysis contained data on at least one of the following: postoperative maximum mouth opening, lateral excursion, protrusion, deviation on opening, asymmetry, and joint pain or muscle pain. Several common statistical …

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Gender And Forgiveness In Early Married Couples, Andrea J. Lerner Jan 2006

Gender And Forgiveness In Early Married Couples, Andrea J. Lerner

Theses and Dissertations

Ninety-five studies that addressed the possibility of gender differences in forgiveness literature are reviewed. Gender differences were examined with respect to predictor variables and outcome variables. Participants were 314 couples from the community who had been married less than one year. Participants filled out questionnaires. Males were more forgiving and were more committed to the marriage. However, females were more successful at granting forgiveness. In addition, females were more religious and reported more symptoms of depression, anxiety, and hostility. Four structural equation models were tested in order to test for gender differences. Structural models including the latent variables of martial …

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Isolation Of Legionella Pneumophila From Well-Maintained Emergency Showers And Eyewash Stations, Jessica Mae Myers Jan 2006

Isolation Of Legionella Pneumophila From Well-Maintained Emergency Showers And Eyewash Stations, Jessica Mae Myers

Theses and Dissertations

Legionella pneumophila is a gram-negative bacterium responsible for Legionnaire's disease, and is commonly transmitted via aerosolized water. Legionella colonization of emergency eyewash and shower stations may pose an exposure hazard to users of these stations. There is little information about the role of these stations as significant reservoirs for Legionella. Samples were collected from 67 stations in an industrial facility. At the time of this study, the stations within this facility were under a routine maintenance program that included at least monthly flushing. This study also included the analysis for other bacterial organisms to determine an association between the presence …

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A Critical Review Of Telomerase Biology And Model Systems For The Study Of Telomerase, Jeremy Charles Aisenberg Jan 2006

A Critical Review Of Telomerase Biology And Model Systems For The Study Of Telomerase, Jeremy Charles Aisenberg

Theses and Dissertations

The study of telomere and telomerase biology holds substantial promise in uncovering the molecular process of aging and the treatment of cancers. Studies have shown that telomere shortening is directly linked to cellular aging and that telomerase expression is found in over 85% of human cancers, including 95% of all advanced malignancies. Development of effective model systems to elucidate the molecular mechanisms underlying the role of telomeres and telomerase in the processes aging and cancer is of particular importance. While inbred strains of mice have provided a wealth of information for a variety of pathways and diseases, the mouse model …

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Mechanisms Of Iron Acquisition Employed By Neisseria Gonorrhoeae For Survival Within Cervical Epithelial Cells, Tracey Ann Hagen Jan 2006

Mechanisms Of Iron Acquisition Employed By Neisseria Gonorrhoeae For Survival Within Cervical Epithelial Cells, Tracey Ann Hagen

Theses and Dissertations

Neisseria gonowhoeae has evolved a repertoire of high-affinity iron acquisition systems to facilitate essential iron uptake in the human host. Acquisition of iron requires both the energy-harnessing cytoplasmic membrane protein, TonB, as well as specific outer membrane TonB-dependent transporters (TdTs). The overall goal of this study was to investigate the extra- and intracellular iron acquisition mechanisms of N. gonorrhoeae and determine the role of the TonB and TdTs in this process.The ability of gonococci to acquire potential exogenous iron sources was determined by plate bioassay. Gonococcal growth was promoted by various catecholate and hydromate siderophores; however, growth was not dependent …

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The Influence Of Sustained Cb1 Blockade During Adolescence On Breakpoints In A Progressive-Ratio Paradigm, Mayo Jerry Wright Jr. Jan 2006

The Influence Of Sustained Cb1 Blockade During Adolescence On Breakpoints In A Progressive-Ratio Paradigm, Mayo Jerry Wright Jr.

Theses and Dissertations

The developmental psychopharmacology of cannabinoids is poorly understood and little is known about the developmental consequences of repeated exposure to cannabinoid antagonists. In these experiments, male Long-Evans rats were treated with SR141716A, a cannabinoid antagonist, throughout adolescence and allowed unrestricted access to food. Control groups were treated with vehicle during the same developmental period and allowed either unrestricted access to food or were pair-fed with a member of the SR-treated group. Motivation to work for food was measured in progressive-ratio sessions at varying levels of food deprivation. For rats that consumed fewer calories throughout adolescence, whether because of pharmacological intervention …

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Implementation Of Image Processing Approach To Translation Of Asl Finger-Spelling To Digital Text, Divya Mandloi Jan 2006

Implementation Of Image Processing Approach To Translation Of Asl Finger-Spelling To Digital Text, Divya Mandloi

Theses

This thesis describes the ongoing development of an image processing technique for the translation of American Sign Language (ASL) finger-spelling to text. The present analysis is the phase one of a broader project, the Sign2 Project, which is focused on a complete technological approach to the translation of ASL to digital audio and/or text. The methodology adopted in this analysis employs a gray-scale image processing technique to convert the American Sign Language finger-spelling to text. It attempts to process static images of the subject considered, and then matches them to a statistical database of pre-processed images to ultimately recognize the …

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Knowledge And Perceived Ambiguity Of Physical Activity Recommendations And Physical Activity In Men And Women In The United States, Laura G. Kiken Jan 2006

Knowledge And Perceived Ambiguity Of Physical Activity Recommendations And Physical Activity In Men And Women In The United States, Laura G. Kiken

Theses and Dissertations

Background: The majority of Americans - especially women - do not meet physical activity recommendations. Having physical activity goals has been associated with physical activity participation, and physical activity recommendations set by public health experts can be viewed as externally set goals. However, past research has shown that goals that are specific rather than ambiguous are more likely to be achieved, and variations in recommendations over time and across sources may have created perceived goal ambiguity.Objectives: This study aimed to (1) examine the extent of physical activity recommendation knowledge among adults in the United States, (2) quantify perceptions of the …

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