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2006

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The Determinants Of Hospital Adoption And Expansion Of Bariatric Procedures: A Resource Dependence Perspective, Wenquiang Tian Jan 2006

The Determinants Of Hospital Adoption And Expansion Of Bariatric Procedures: A Resource Dependence Perspective, Wenquiang Tian

Theses and Dissertations

New medical technologies have been viewed as the primary cause of rising health are expenditures by health policy researchers in the United States. Since the mid 1990s, with the prevalence of obesity among Americans, the utilization of bariatric surgery, a medical innovation, has increased rapidly among U.S. hospitals. Generally, current literature only states that the volume of bariatric procedures is increasing dramatically.Very limited studies have been conducted to investigate the growth of bariatric procedures.The objective of this study is (1) to provide a detailed description about the adoption and utilization of bariatric procedure in hospitals in 11 states, and (2) …

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Parent And Therapist Perceptions Of Sensory Based Strategies Used By Occupational Therapists In Family-Centered Early Intervention Practice, Juliet Bertaut Copeland Jan 2006

Parent And Therapist Perceptions Of Sensory Based Strategies Used By Occupational Therapists In Family-Centered Early Intervention Practice, Juliet Bertaut Copeland

Theses and Dissertations

A qualitative approach was used to explore the perceptions of parents and therapists in early intervention regarding sensory diets and their efficacy, particularly their goodness of fit within family routines and occupations. Open-ended interviews were conducted with therapist and parent participants and analysis of the data resulted in a model depicting how sensory diets became a "way of life" for families. The Sensory Diet "Way of Life" Model revealed seven themes that illustrated how occupational therapists in early intervention enter the homes of the families they serve and establish a "partnership" with parents to address a child's needs. Once this …

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Information Technology Outsourcing In U.S. Hospital Systems, Mark L. Diana Jan 2006

Information Technology Outsourcing In U.S. Hospital Systems, Mark L. Diana

Theses and Dissertations

The purpose of this study was to determine the factors associated with outsourcing of information systems (IS), and if there is a difference in IS sourcing based on the strategic value of the outsourced functions. The theoretical framework is based upon a synthesis of strategic management theory (SMT) and transaction cost economics (TCE) as they apply to vertical integration in the health care sector; therefore, IS sourcing behavior was conceptualized as a case of vertical integration. The conceptual model proposed that sourcing behavior would be determined by asset specificity, uncertainty, the interaction of asset specificity and uncertainty, bargaining power, corporate …

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A Comparison For Longitudinal Data Missing Due To Truncation, Rong Liu Jan 2006

A Comparison For Longitudinal Data Missing Due To Truncation, Rong Liu

Theses and Dissertations

Many longitudinal clinical studies suffer from patient dropout. Often the dropout is nonignorable and the missing mechanism needs to be incorporated in the analysis. The methods handling missing data make various assumptions about the missing mechanism, and their utility in practice depends on whether these assumptions apply in a specific application. Ramakrishnan and Wang (2005) proposed a method (MDT) to handle nonignorable missing data, where missing is due to the observations exceeding an unobserved threshold. Assuming that the observations arise from a truncated normal distribution, they suggested an EM algorithm to simplify the estimation.In this dissertation the EM algorithm is …

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Public: An Exploration Of Community, Environment, And Technology, Christopher John Malven Jan 2006

Public: An Exploration Of Community, Environment, And Technology, Christopher John Malven

Theses and Dissertations

This project examines the potential of computer technology to enhance navigation within, and incorporate information-sharing into, the public urban environment.

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The Influence Of A Single Nucleotide Polymorphism In The Matrix Metalloproteinase-1 Promoter On Glioma Biology, Jessica Mccready Jan 2006

The Influence Of A Single Nucleotide Polymorphism In The Matrix Metalloproteinase-1 Promoter On Glioma Biology, Jessica Mccready

Theses and Dissertations

Glioblastomas are an incurable type of brain tumor with a mean survival time of 9-12 months following diagnosis. One of the reasons for this poor prognosis is the ability of tumor cells to invade the surrounding normal brain tissue. Enzymes responsible for this invasive nature include the matrix metalloproteinase family. MMP-1 is a member of this family which has been well studied in many types of invasive tumors, with gliomas being an exception. We studied a single nucleotide polymorphism (SNP) in the MMP-1 promoter that may influence glioma biology. This SNP consists of the presence (2G) or absence (1G) of …

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Perceived Deprivation In Active Duty Military Nurse Anesthetists, Julie Ann Pearson Jan 2006

Perceived Deprivation In Active Duty Military Nurse Anesthetists, Julie Ann Pearson

Theses and Dissertations

Problem: There is a shortage of military certified registered nurse anesthetists (CRNAs). The exodus from military service to civilian careers could be a result of relative deprivation (the discrepancy that one perceives between what one has and what one could or should have). Relative deprivation is a perception of unfairness dependent on feelings (subjective data) as well as facts (objective data). Purpose: The purpose of this study was to measure relative deprivation in active duty military nurse anesthetists, to explore variables which correlate with relative deprivation, and to validate or refute the theory of relative deprivation in active duty military …

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Action Of Tyrosyl Dna Phosphodiesterase On 3'-Phosphoglycolate Terminated Dna Strand Breaks, Haritha Tatavarthi Jan 2006

Action Of Tyrosyl Dna Phosphodiesterase On 3'-Phosphoglycolate Terminated Dna Strand Breaks, Haritha Tatavarthi

Theses and Dissertations

Free radical-mediated DNA double strand breaks (DSBs) are induced either directly by ionizing radiation or by certain chemicals like bleomycin. These breaks are terminated by 3'-PG (PO4CH2COOˉ) or 3'-phosphate groups formed as a result of fragmentation of deoxyribose. To study the nature of repair of these 3'-blocked breaks, we constructed substrates mimicking free-radical induced DSBs. Human and yeast tyrosyl DNA-phosphodiesterase (Tdpl) efficiently processed substrates with 3'-PGs, in either the presence or absence of magnesium, to give a 3'-phosphate. Gel filtration chromatography and western blotting codmed that the putative enzyme in human extracts that efficiently processed PG was indeed tyrosyl DNA-phosphodiesterase. …

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A Determination Of The Association Of Competition And Regulation With Hospital Strategic Orientation, Kathleen B. Heatwole Jan 2006

A Determination Of The Association Of Competition And Regulation With Hospital Strategic Orientation, Kathleen B. Heatwole

Theses and Dissertations

This research study examines the influence of two major forces, competition and regulation, on the strategic orientation of hospitals. This is a particularly relevant subject, as the effectiveness of competition versus the effectiveness of regulation in the health care market has been called one of the Bellwether issues in health care policy, and the most controversial and far reaching philosophical battle facing the health care industry. Even after three decades of research and debate, there is still no consensus on how the hospital industry responds to either a competitive environment or a regulated environment. There continues to be significant variation …

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A Study Of The Relationship Between School Climate And Student Performance On The Virginia Standards Of Learning Tests In Elementary Schools, Victoria Lee Thomasson Jan 2006

A Study Of The Relationship Between School Climate And Student Performance On The Virginia Standards Of Learning Tests In Elementary Schools, Victoria Lee Thomasson

Theses and Dissertations

Educators are examining many aspects of schools as they find ways to help students improve their performance on standardized tests in order to meet both federal and state standards. This study examined the relationship between organizational climate and student achievement on the Virginia Standards of Learning tests. A total of 1,061 teachers in 47 schools across the Commonwealth of Virginia responded to the climate survey. The survey instrument was the Organizational Health Inventory for Elementary Schools (OHI-E). This brief survey instrument examined five aspects of school climate. They were Teacher Affiliation, Collegial Leadership, Resource Influence, Institutional Integrity, and Academic Emphasis. …

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Impact Of Terrorism On Migration Patterns In Turkey, Yilmaz Simsek Jan 2006

Impact Of Terrorism On Migration Patterns In Turkey, Yilmaz Simsek

Theses and Dissertations

This study is among the first studies that evaluate the social impacts of terrorism in a specific country for a 10 year period. It tests the effects of terrorism on domestic net-migration in Turkey, especially in the terror infected provinces of the Eastern and South Eastern regions of the country between the years 1992 and 2001. Terrorism has impacted people not only physically, but also psychologically. When faced with "future uncertainty" or the "fear of terrorism," it is natural for people to leave their home towns, and to migrate to somewhere else where they feel safe. In order to explore …

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Social Change, Gender And Education: Exceptional Swedish Immigrant Women At North Park College, 1900-1920, Sofia A.T. Hiort Wright Jan 2006

Social Change, Gender And Education: Exceptional Swedish Immigrant Women At North Park College, 1900-1920, Sofia A.T. Hiort Wright

Theses and Dissertations

The present study focused on the educational and career experiences of four selected Swedish immigrant women at North Park College in Chicago from 1900-1920. There is a gap in the extant literature with regard to the Swedish immigrant women experiences, and this study attempted to shed some light on this fascinating topic.The study examined the lives of three selected Swedish immigrant women students at the College and their lives afterwards as missionaries in China. It also examined the life of Lena Sahlstrom, a faculty member at North Park College during the same period. The four women were exceptional individuals, each …

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Glutamate Excitotoxicty Activates A Novel Calcium Permeable Ion Channel In Cultured Hippocampal Neurons, Laxmikant Sudhir Deshpande Jan 2006

Glutamate Excitotoxicty Activates A Novel Calcium Permeable Ion Channel In Cultured Hippocampal Neurons, Laxmikant Sudhir Deshpande

Theses and Dissertations

Glutamate excitotoxicity is the predominant mechanism implicated in neuronal cell death associated with neurological disorders such as stroke, epilepsy, traumatic brain injury and ALS. Excessive stimulation of NMDA subtypes of glutamate receptors leads to protracted intracellular calcium elevations triggering calcium mediated neurotoxic mechanisms culminating in delayed neuronal cell death. In addition, glutamate excitotoxicity induces a NMDA dependent extended neuronal depolarization mediated by continuous calcium influx that correlates with delayed neuronal death. Attempts to prevent neuronal death by blocking calcium entry into the neurons using calcium channel blockers or NMDA receptor antagonists have failed to provide any beneficial effects in clinical …

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What Cost Hospital Quality: Performance Uncertainty Under Market Reform, Ronald L. Fisher Jan 2006

What Cost Hospital Quality: Performance Uncertainty Under Market Reform, Ronald L. Fisher

Theses and Dissertations

Healthcare is an organizational field that has undergone profound change in the last few decades, an era characterized by market reform. Healthcare production has revealed both economic and quality problems in past eras, and reporting on these problems can be seen to have contributed to pressures for social reform. Yet, the move toward more market-oriented governance structures and design solutions also reflects a wider isomorphic institutional tendency for organizing social order.The conceptual frame work of this study takes a pessimistic stance on whether the market reform has achieved the intended goals with respect to advancing organizational quality performance. The framework …

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Modulation Of The Serotonin Reuptake Transporter In Raw264.7 Macrophages, Sienna Marie Arenas Malubay Jan 2006

Modulation Of The Serotonin Reuptake Transporter In Raw264.7 Macrophages, Sienna Marie Arenas Malubay

Theses and Dissertations

Serotonin (5-HT) plays an important role as both a neurotransmitter and animmune modulator. The serotonin reuptake transporter (SERT) clears the extracellular space of 5-HT, which decreases the effects of 5-HT on target cells. This study demonstrated that the RAW264.7 macrophage cell line expresses SERT function, measured by assays of 3H-5HT uptake. The 5-HT uptake in RAW264.7 macrophages was more than 10-fold that of peritoneal macrophages, indicating that these cells are an excellent model for studying regulation of the SERT. Activation of macrophages with lipopolysaccharide (LPS) increased SERT activity in a time- and concentration-dependent manner and Western blots indicate that the …

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Discovery Of Lignin Sulfate As A Potent Inhibitor Of Hsv Entry Into Cells, Jay N. Thakkar Jan 2006

Discovery Of Lignin Sulfate As A Potent Inhibitor Of Hsv Entry Into Cells, Jay N. Thakkar

Theses and Dissertations

The herpes virus family consists of more than hundred members that infect organisms, of which eight, differing markedly in the biology are known to infect humans. HSV- I is the most common one, causing oral lesions and sporadic encephalitis. These infections are highly prevalent affecting at least one in three individuals in the United States.The entry of the herpes virus into the cell is a two-step process. The initial step involves the cell surface heparan sulfate and glycoproteins in the viral envelope which enables the virus to penetrate into the cell. The second step is the fusion step. Depending on …

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R. Walton Moore And Virginia Politics, 1933-1941, Daniel Gregory Tulli Jan 2006

R. Walton Moore And Virginia Politics, 1933-1941, Daniel Gregory Tulli

Theses and Dissertations

This study is a chronicle of the efforts of R. Walton Moore and the Roosevelt Administration to liberalize the conservative Virginia Democratic Party during the 1930's. Moore was an elderly politician and amateur historian who had been in and out politics in the state for over forty years. He was opposed at every turn in his efforts by state Democratic Party organization leader Senator Harry F. Byrd, and his conservative colleague Senator Carter Glass. Both Glass and Byrd opposed most New Deal legislation throughout the decade. Moore served officially as Assistant Secretary of State and Counselor to the State Department, …

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Sec Regulation Of Corporate 10k Filing Dates: The Effect On Earnings Management And Market Recognition, Robert W. Russ Jan 2006

Sec Regulation Of Corporate 10k Filing Dates: The Effect On Earnings Management And Market Recognition, Robert W. Russ

Theses and Dissertations

In November 2002, the Securities and Exchange Commission released a final ruling regarding a filing requirement change. The proposed requiredment change was for domestic companies to file annual and quarterly reports within 60 and 30 days, respectfully. This requirement was recommended for companies with a market value of at least $75 million and would reduce by 30 days the time allowed to file these reports. The Wall Street Journal article announcing this proposal stated the change was an effort to address some of the problems arising from accounting scandals such as the Enron scandal of 2001. A potential added benefit …

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Panic Disorder, Trait Anxiety, And Risk Drinking In Pregnant And Non-Pregnant Women, Sarah Meshberg-Cohen Jan 2006

Panic Disorder, Trait Anxiety, And Risk Drinking In Pregnant And Non-Pregnant Women, Sarah Meshberg-Cohen

Theses and Dissertations

Anxiety disorders, including Panic Disorder, and alcohol problems co-occur at greater rates than chance in the general population. It has also been suggested that alcohol is used to cope with anxiety symptoms, such as trait anxiety. While pregnancy may be a protective period against Panic Disorder and panic symptoms, trait anxiety remains relatively stable during pregnancy. The purpose of the present study was to examine differences in rates of current Panic Disorder, panic attacks, and trait anxiety in pregnant and non-pregnant women receiving care at an urban OB/GYN clinic. The study also examined correlates and differences in alcohol use and …

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Implicit Theories Of Weight Management: A Social Cognitive Approach To Motivation, Jeni L. Burnette Jan 2006

Implicit Theories Of Weight Management: A Social Cognitive Approach To Motivation, Jeni L. Burnette

Theses and Dissertations

Just as scientists develop general conceptual explanations of the phenomena they investigate, individuals also develop intuitive theories about such human characteristics as intelligence, personality, and athletic ability. These theories, unlike scientist's theories, are not explicitly articulated or documented, and so they are termed implicit theories. Implicit theories, in achievement motivation, distinguish between the belief that human attributes are fixed (entity theory) or malleable (incremental theory) and have been shown to have far-reaching consequences for motivation, goal-orientations, and regulatory strategies in an array of domains. This dissertation extended implicit theories research to the domain of body-weight management. Drawing from an elaborate …

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Hospitals' Decision To Vertically Integrate Skilled Nursing Units Before And After The Balanced Budget Act, Betty C. Lucente Jan 2006

Hospitals' Decision To Vertically Integrate Skilled Nursing Units Before And After The Balanced Budget Act, Betty C. Lucente

Theses and Dissertations

The decision to vertically integrate services and deliver care has both management and policy concerns for healthcare in the United States. The change in reimbursement, which was enacted with the Balanced Budget Act of 1997, influenced the availability of post acute services for acute hospital inpatients. Prior to this change, post acute services were reimbursed based on cost similar to the pre DRG era of Medicare reimbursement. The change in payment had the potential to make discharging patients more difficult resulting in a prolonged length of stay without additional payment and at increased costs for hospitals. As a result of …

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Relationships Among Stress, Blood Pressure, And Heart Rate Variability In Meditators, Sangthong Terathongkum Jan 2006

Relationships Among Stress, Blood Pressure, And Heart Rate Variability In Meditators, Sangthong Terathongkum

Theses and Dissertations

PROBLEM STATEMENT: Growing evidence indicates that psychological stress contributes to cardiovascular diseases through complex neuroendocrine mechanisms. Psychological stress leads to several physiological responses including increased heart rate (HR) and blood pressure (BP) as well as decreased heart rate variability (HRV) through alterations in the autonomic nervous system (ANS), specifically increased sympathetic nervous system (SNS) activity and decreased parasympathetic nervous system (PNS) activity. Meditation is thought to induce an innate relaxation response leading to reduced psychological stress. Findings from past studies have provided inconclusive evidence regarding the direction and strength of relationships among stress, BP, HRV, and meditation practice. PROCEDURES: A …

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An Exploration Of How And Why Primary Care Providers Educate Infant Caregivers About Positioning, Amy Greenspon Choffin Jan 2006

An Exploration Of How And Why Primary Care Providers Educate Infant Caregivers About Positioning, Amy Greenspon Choffin

Theses and Dissertations

A review of the literature indicates that how infants are positioned is related to the risk of SIDS, the incidence and severity of plagiocephaly, torticollis, and developmental delays. A quantitative approach with survey methodology was used with 66 pediatric primary care providers responding to 26 questions. Overall, PCPs are educating caregivers about sleep positioning with a high frequency. There was a relationship between practice site, and the frequency of sleep positioning education is provided. While the participants provide education about awake positioning, and the use of positioning devices, it was with less frequency than they do about sleep positioning; there …

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A Model To Predict 24-Hour Urinary Creatinine Level Using Repeated Measurements, Donna S. Kroos Jan 2006

A Model To Predict 24-Hour Urinary Creatinine Level Using Repeated Measurements, Donna S. Kroos

Theses and Dissertations

Creatinine is a metabolic waste product, removed from the blood by the kidneys, and excreted in the urine. The measurement of creatinine is used in the assessment and monitoring of many medical conditions as well as in the determination or adjustment of absorbed dosage of pesticides. Earlier models to predict 24-hour urinary creatinine used ordinary least squares regression and assumed that the subjects' observations were uncorrelated. However, many of these studies had repeated creatinine measurements for each of their subjects. Repeated measures on the same subject frequently are correlated. Using data from the NIOSH-CDC "Pesticide Dose Monitoring in Turf Applicators" …

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The Role Of Dna Methylation And Methyl Binding Domain Protein 2 In The Regulation Of Human Embryonic And Fetal Beta Type Globin Genes, Jeremy William Rupon Jan 2006

The Role Of Dna Methylation And Methyl Binding Domain Protein 2 In The Regulation Of Human Embryonic And Fetal Beta Type Globin Genes, Jeremy William Rupon

Theses and Dissertations

The genes of the human β-globin locus are located on chromosome 11 in the order of their expression during development: 5' ε, γ, β 3'. During development, silencing of the 5' gene occurs with activation of the immediate 3' gene. This process occurs twice and is termed hemoglobin switching. The exact mechanism(s) of this process have not been fully described. Herein, we describe a role for DNA methylation and methyl binding domain protein 2 in the transcriptional regulation of the human embryonic and fetal beta type globin genes. Adult mice containing the entire human β-globin locus as a yeast artificial …

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Studies On The Molecular Biology Of Naegleru Fowleri And Identification Of N. Fowleri In The Environment, Rebecca Carmean Maclean Jan 2006

Studies On The Molecular Biology Of Naegleru Fowleri And Identification Of N. Fowleri In The Environment, Rebecca Carmean Maclean

Theses and Dissertations

Naegleria fowleri, a free-living ameboflagellate, is the causative agent of primary amebic meningoencephalitis. Healthy humans sporadically become infected with N. fowleri and develop fatal PAM after recreational or work exposure to freshwater; accordingly, there is a need for monitoring the presence of pathogenic amebeflagellates in public freshwater. The present study was conducted to determine whether a nested PCR assay could be used for detection of N. fowleri in freshwater habitats. PCR analysis was used to test samples from Virginia, Connecticut, Arizona, and Oklahoma for the presence of N. fowleri in lakes, ponds, soil, and domestic water supplies. The amebae were …

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Pathological Upregulation Of A Calcium-Stimulated Phosphatase, Calcineurin, In Two Models Of Neuronal Injury, Jonathan Elledge Kurz Jan 2006

Pathological Upregulation Of A Calcium-Stimulated Phosphatase, Calcineurin, In Two Models Of Neuronal Injury, Jonathan Elledge Kurz

Theses and Dissertations

Excitotoxic calcium influx and activation of calcium-regulated systems is a common event in several types of neuronal injury. This mechanism has been the focus of intense research, with the hope that a more complete understanding of how neuronal injury affects calcium-regulated systems will provide effective treatment options. This study examines one such calcium-stimulated enzyme, calcineurin, in the context of two common neurological pathologies, status epilepticus and traumatic brain injury.Status epilepticus was induced by pilocarpine injection. NMDA-dependent increases in calcineurin activity were observed in cortical and hippocampal homogenates. Upon closer examination, the most profound increases in activity were found to be …

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Forecasting Stability Levels For The Countries Of The Former Soviet Union, Margaret Erin Keck Jan 2006

Forecasting Stability Levels For The Countries Of The Former Soviet Union, Margaret Erin Keck

Theses and Dissertations

United States intelligence officers and policymakers need reliable forecasts of country, regional, and global stability or instability. Such forecasts require a methodology for identifying and analyzing factors that contribute to stability. The anticipation of this stability level can facilitate crisis warning and diplomatic strategies for various timelines, including five, ten, and twenty year forecasts. While the problem of forecasting can be tackled in various ways, in the interest of time and space, I will only go into a few of them. The approach I will use is multiple linear regression to generate a short-term forecast for the stability levels of …

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The Influence Of Perceptions And Experiences Of Racial Discrimination On Body Mass Index Among The Black Women's Health Study Cohort, Dana-Marie Thomas Jan 2006

The Influence Of Perceptions And Experiences Of Racial Discrimination On Body Mass Index Among The Black Women's Health Study Cohort, Dana-Marie Thomas

Theses and Dissertations

Using data from the Black Women's Health Study (BWHS) and building on what is currently known about perceptions of racism and discrimination and its mechanisms, this study attempts to demonstrate the value of identifying additional variables that may serve as potential risk factors for obesity among African American women. Using secondary data analysis, the purpose of this study was to expand the scope of existing obesity research by examining a 1997 cross-sectional dataset of self-reported questionnaire responses among a random sample of African American women enrolled in the Black Women's Health Study (BWHS) to examine the association between perceptions of …

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Autism Spectrum Disorders And Workplace Discrimination: An Empirical Analysis Of Eeoc-Resolved Ada Title I Charges, Wieren Todd Alan Van Jan 2006

Autism Spectrum Disorders And Workplace Discrimination: An Empirical Analysis Of Eeoc-Resolved Ada Title I Charges, Wieren Todd Alan Van

Theses and Dissertations

The purpose of this quantitative, non-experimental, retrospective research study was to examine the charges of disability-related, private-sector workplace discrimination made by individuals with Autism Spectrum Disorders (ASDs) to the Equal Employment Opportunity Commission (EEOC), under Title I of the Americans with Disabilities Act (ADA). To date, there has been a lack of research regarding the nature, scope and dynamics of employment discrimination affecting individuals with ASDs.A portion of the EEOC's Integrated Mission Systems (IMS) database was analyzed, drawing upon the following five major categories: (1) charging-party demographics, (2) responding-party characteristics, (3), U.S. region, (4) ADA Title I discrimination charge categories, …

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