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2006

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Use Of A Synthetic Substrate For Orthodontic Bond Strength Testing, Elijah B. Saikaly Jan 2006

Use Of A Synthetic Substrate For Orthodontic Bond Strength Testing, Elijah B. Saikaly

Theses and Dissertations

In vitro bond strength studies are of great importance and interest since they allow the prediction of clinical success of orthodontic adhesives. There are many studies that have investigated bond strength values of bonding systems. However, due to the variation in the materials and methods employed, it is very difficult and often impossible to make comparisons among data. The use of a substrate as an alternate to enamel for mechanical tests would minimize these variables and reduce the challenges faced with in vitro bond strength tests. The purpose of this study was to investigate the suitability of Macor as a …

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Characterization Of Perphenazine And Scopolamine Aerosols Generated Using The Capillary Aerosol Generator, Xihao Li Jan 2006

Characterization Of Perphenazine And Scopolamine Aerosols Generated Using The Capillary Aerosol Generator, Xihao Li

Theses and Dissertations

The characterization of perphenazine and scopolamine aerosols generated using the capillary aerosol generator (CAG) was reported. Variables including steady state power, the formulation vehicle, the drug concentration and the formulation flow rate were studied for their effects on the chemical stability and particle size of these drug aerosols.Stability-indicating HPLC and LC-MS assays were developed and validated for perphenazine and scopolamine, respectively. The chemical stability of each compound was investigated under a variety of stress conditions and the structure of degradation products was proposed.Perphenazine aerosols were generated from propylene glycol (PG) formulations with concentrations of 9, 48 and 90mM at formulation …

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Diffuse Brain Injury Triggers Ultra-Rapid Perisomatic Traumatic Axonal Injury, Wallerian Change, And Non-Specific Inflammatory Responses, Brian Joseph Kelley Jan 2006

Diffuse Brain Injury Triggers Ultra-Rapid Perisomatic Traumatic Axonal Injury, Wallerian Change, And Non-Specific Inflammatory Responses, Brian Joseph Kelley

Theses and Dissertations

A significant component of diffuse brain injury (DBI) is diffuse axonal injury (DAI) which is responsible for the morbidity and mortality associated with this condition. DAI and its experimental counterpart traumatic axonal injury (TAI) result in scattered microscopic pathology characterized by focal impairment of axonal transport leading to progressive swelling and delayed axotomy. DBI-mediated perisomatic axotomy does not result in acute neuronal death suggesting that delayed axotomy was responsible for this unanticipated response. To evaluate this hypothesis, we examined the spatiotemporal progression of DBI-mediated perisomatic TAI. LM / TEM identified impaired axonal transport within 15 - 30 min post-injury. Perisomatic …

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Ige Production Regulation Via Cd23 Stalk Engagement And Cell Cycle Stimulation, Timothy Hays Caven Jan 2006

Ige Production Regulation Via Cd23 Stalk Engagement And Cell Cycle Stimulation, Timothy Hays Caven

Theses and Dissertations

CD23, the low affinity receptor for IgE, is expressed mainly on B cells and has been shown to regulate IgE production. Previously, recombinant mouse and human CD23 were constructed with a trimerizing isoleucine zipper motif attached in frame to the N-terminus of the entire extracellular CD23 (lz-ECCD23). The goal was to examine the role of the necessity of the CD23 stalk for binding IgE. Using PCR-based mutagenesis to delete the majority of the stalk, binding to IgE was lost. Further studies examined the effect of lz-ECCD23 in preventing IgE from binding FcεRI and therefore acting as a therapeutic agent. It …

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The Expression And Function Of Wilms' Tumor 1 In Malignant Glioma, Aaron J. Clark Jan 2006

The Expression And Function Of Wilms' Tumor 1 In Malignant Glioma, Aaron J. Clark

Theses and Dissertations

The Wilms' tumor 1 gene is overexpressed in many types of cancer and is associated with poor prognosis and resistance to anti-cancer therapies. In vitro studies in non-glioma cells types have demonstrated that WTl plays a role in increased proliferation, resistance to apoptosis, and increased cellular invasion. We aimed to thoroughly characterize the expression pattern of Wilms' tumor 1 in human malignant glioma and discern its function in this complex disease process. We screened a large sample of established human malignant glioma cell lines and glioma tissue specimens of all grades for WT1 expression. The majority of cell lines and …

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Comparison Of Leukocyte Classes Most Likely To Cause Vascular Dysfunction In Preeclampsia, Kristen Anne Cadden Jan 2006

Comparison Of Leukocyte Classes Most Likely To Cause Vascular Dysfunction In Preeclampsia, Kristen Anne Cadden

Theses and Dissertations

Leukocytes are activated in women with preeclampsia, but the class of leukocyte most likely to cause vascular dysfunction is not known. We hypothesized that neutrophils may be the class of leukocyte most involved in causing this dysfunction because neutrophils are the most abundant of the leukocytes and their numbers increase during pregnancy. In this study we compared vascular infiltration of neutrophils (CD66b) with monocytes/macrophages (CD14) and lymphocytes (CD99) in normal non-pregnant women (NNP), normal pregnant women (NP), and preeclamptic women (PE). There was no significant difference in the infiltration of lymphocytes into the maternal vasculature in PE as compared to …

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A Model For Studying Vasogenic Brain Edema, Anshu Shukla Jan 2006

A Model For Studying Vasogenic Brain Edema, Anshu Shukla

Theses and Dissertations

Convection-enhanced delivery (CED) is a proven method for targeted drug delivery to the brain that circumvents the blood-brain barrier (BBB). Little study has been conducted in understanding CED in pathological brain states. This is of importance when dealing with chemotherapeutic agent delivery to brain tumors, where vasogenic edema (VE) exists. The current study aims to characterize a model of VE suitable for studying CED.VE was produced in the right hemisphere of the rat brain using multiple infusions of hyperosmotic mannitol (0.25mL/kg/s over 30 seconds) delivered through the right internal carotid artery. Magnetic resonance imaging (MRI) revealed consistent edema formation and …

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The Motives And Experiences Of College Students Who Choose To Abstain From Drinking Alcohol, Lisa Proakis-Stone Jan 2006

The Motives And Experiences Of College Students Who Choose To Abstain From Drinking Alcohol, Lisa Proakis-Stone

Theses and Dissertations

Objective: Numerous studies trying to find the causes and implications of binge drinking on college campuses have focused their attention on the heavy drinkers. The purpose of this study was to understand why and how college students choose to abstain from drinking. The study also examined the experiences of the abstaining college students on a campus where 83% of the student body drinks. Methods: Twelve undergraduate students from the University of Richmond participated in this qualitative study. Individual interviews using open-ended questions were conducted to ascertain the reasons for their abstinence and their experiences as college students. After the interviews, …

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Autocrine Effects Of Catecholamines On Macrophage Release Of Interleukin-6 (Il-6), Shaunta D. Poe Jan 2006

Autocrine Effects Of Catecholamines On Macrophage Release Of Interleukin-6 (Il-6), Shaunta D. Poe

Theses and Dissertations

Effects of norepinephrine (NE) on macrophage cytokine release are complex because the cells have both α2 and β2 adrenergic receptors, which mediate opposing actions. Furthermore, β2-adrenergic agonists are reported to have both stimulatory and inhibitory effects on interleukin-6 (IL-6). This study was designed to clarify the autocrine role of macrophage-derived NE on IL-6 production in activated peritoneal macrophages. Effects of NE on IL-6 production in the RAW264.7 macrophage cell-line also were investigated. Treatment of activated peritoneal macrophages with endotoxin, the α2-adrenergic antagonists yohimbine or RS79948 revealed that the α2-adrenergic receptor mediates a stimulatory autocrine action of catecholamines on IL-6 production. …

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Rehabilitating The "Mystery Passage": An Examination Of The Supreme Court's Anthropology Using The Personalistic Norm Explicit In The Philosophy Of Karol Wojtyla, Michael A. Scaperlanda Jan 2006

Rehabilitating The "Mystery Passage": An Examination Of The Supreme Court's Anthropology Using The Personalistic Norm Explicit In The Philosophy Of Karol Wojtyla, Michael A. Scaperlanda

Faculty Articles

No abstract provided.

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Never Get Out'a The Boat: Stenberg V. Carhart And The Future Of American Law, John Breen, Michael A. Scaperlanda Jan 2006

Never Get Out'a The Boat: Stenberg V. Carhart And The Future Of American Law, John Breen, Michael A. Scaperlanda

Faculty Articles

No abstract provided.

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The Challenges Of Itil Implementations, Jason Gray Jan 2006

The Challenges Of Itil Implementations, Jason Gray

Theses : Honours

Originating from the UK, the IT Infrastructure Library (ITIL) is an IT Service Management framework whose adoption is rapidly spreading throughout Canada, Netherlands, South Africa, India, USA, and Australia. Promoted as a collection of "Best Practices" in IT service management, ITIL is gaining a reputation as a "silver bullet" to IT Service Management woes and is now .gaining popularity amongst IT vendors and leaders of best practices worldwide. Increased IT productivity, IT accountability, increased compliance and reduced IT costs, are just some of the promised list of benefits. More and more organisations are plam1ing to embark on ITIL implementations as …

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Water Stress Vulnerability Of Four Banksia Species In Contrasting Ecohydrological Habitats On The Gnangara Mound, Western Australia, Caroline Canham Jan 2006

Water Stress Vulnerability Of Four Banksia Species In Contrasting Ecohydrological Habitats On The Gnangara Mound, Western Australia, Caroline Canham

Theses : Honours

The distribution of obligate and facultative phreatophytic vegetation reflects the gradient of ecohydrological habitats in a landscape. Preliminary investigations of Banksia vulnerability to xylem embolism have reported that obligate phreatophytes are more susceptible to water stress than facultative phreatophytes (Froend & Drake 2006). A quantitative measure of plant susceptibility to water stress is vital when establishing environmental water requirements. This study investigated interspecific differences in vulnerability to water stress for two facultative phreatophytes (B. attenuata and B. menziesii) and two obligate pln·eatophytes (B. ilicifolia and B. littoralis) at the same position along an ecohydrological gradient on the Gnangara Groundwater Mound, …

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A Model For Successful Teamwork, Mohamed Bakir Jan 2006

A Model For Successful Teamwork, Mohamed Bakir

Theses : Honours

Increasingly, there have been greater expectations from industry and employers that universities in Australian focus on developing student generic skills, core competencies or graduate attributes. As a result, key skills included in the mission statements of most universities tend to include higher-level aims relating to critical thinking, lifelong learning and teamwork. These generic skills and others, are considered essential for successful work place practice and universities are constantly being called upon to produce graduates that can show these skills. This is not an easy task, and universities are trying different approaches to try and satisfy these needs, e.g. e-portfolios and …

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An Attitude And Perception Study Of Wireless Network Usage In Home Environments, Patryk Szewczyk Jan 2006

An Attitude And Perception Study Of Wireless Network Usage In Home Environments, Patryk Szewczyk

Theses : Honours

Research on the use of 802.11 wireless networking and wireless security has in the past focused predominantly on corporations who generally have access to resources specifically allocated to computer and network security. Research has also focused on identifying the flaws in wireless network security, and developing stronger and safer methods which may be incorporated. To date there has been a lack of research into determining what the individual at home perceives towards wireless security. As broadband Internet connections are now predominantly chosen, the amount of available bandwidth open to exploitation is significantly higher than the now becoming obsolete dialup connection. …

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Transforming Messiaen : The Application Of Elements Of The Musical Language Of Olivier Messiaen To The Contemporary Jazz Orchestra, Johannes Luebbers Jan 2006

Transforming Messiaen : The Application Of Elements Of The Musical Language Of Olivier Messiaen To The Contemporary Jazz Orchestra, Johannes Luebbers

Theses : Honours

The music of Olivier Messiaen is a unique and interesting contribution to the canon of 20th Century art music, but one that has received little attention from the jazz world. Through a detailed study of his music, this dissertation aims to gain a deeper understanding of Messiaen's musical language and investigate the possibilities of applying that language within the jazz idiom. In addition to a discussion of Messiaen and his music, a detailed analysis of the author's own composition for pipe organ and jazz orchestra, Auguries of Innocence, will explore the results of this application. The complete scores and …

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Variations Among Regions And Hospitals In Managing Chronic Illness: How Much Care Is Enough?, John E. Wennberg Jan 2006

Variations Among Regions And Hospitals In Managing Chronic Illness: How Much Care Is Enough?, John E. Wennberg

Center for Policy Research

Classic epidemiology looks at what happens to people who live in a defined region over time. For example, birth rate, the number of births that occur among populations over a year, is a common statistics that we're all familiar with. Since the early 1990s we have conducted research at Dartmouth Medical School to convert that classic epidemiologic perspective into looking at what is happening in terms of the health care system itself. We ask how much care people are getting in different regions of the country. We want to know the patterns of that care. And we want to get …

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Foreword To Conference Report: The New York City Housing Court In The 21st Century: Can It Better Address The Problems Before It?, Ellen Yaroshefsky, Marilyn J. Flood Jan 2006

Foreword To Conference Report: The New York City Housing Court In The 21st Century: Can It Better Address The Problems Before It?, Ellen Yaroshefsky, Marilyn J. Flood

Cardozo Public Law, Policy & Ethics Journal

The New York City Housing Court faces significant challenges in addressing housing disputes, particularly due to the high number of pro se litigants and the intersection of legal and social issues that contribute to homelessness. A 2004 conference brought together diverse stakeholders to examine these challenges and propose reforms, focusing on six key areas: pre-adjudication steps, the adjudicative process, the right to counsel, litigants of diminished capacity, preserving housing stock, and social services. The conference emphasized the need for systemic changes to improve access to justice and efficiency in the court.

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How Will Declining Rates Of Marriage Reshape Eligibility For Social Security?, Madonna Harrington Meyer, Douglas A. Wolf, Christine L. Himes Jan 2006

How Will Declining Rates Of Marriage Reshape Eligibility For Social Security?, Madonna Harrington Meyer, Douglas A. Wolf, Christine L. Himes

Center for Policy Research

For most older people in the United States, Social Security is the major source of income: nine out of ten people age 65 or older receive benefits, which represent an average of 41 percent of their income. Largely as a result of Social Security, poverty rates for the elderly are at an all-time low, just 10 percent. But pockets of poverty persist: older unmarried persons, blacks, and Hispanics experience poverty rates in excess of 20 percent, and over 40 percent of all older single black women live in poverty. People quality for Social Security based either on their work record …

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Pinning Down The Value Of Statistical Life, Thomas J. Kniesner, W. Kip Viscusi, Christopher Woock, James P. Ziliak Jan 2006

Pinning Down The Value Of Statistical Life, Thomas J. Kniesner, W. Kip Viscusi, Christopher Woock, James P. Ziliak

Center for Policy Research

Our research addresses fundamental long-standing concerns in the compensating wage differentials literature and its public policy implications: the econometric properties of estimates of the value of statistical life (VSL) and the wide range of such estimates from about $0.5 million to about $21 million. We address most of the prominent econometric issues by applying panel data, a new and more accurate fatality risk measure, and systematic selection of panel estimator in our research. Controlling for measurement error, endogeneity, individual heterogeneity, and state dependence yields both a reasonable average level and narrow range for the estimated value of a statistical life …

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Applying Principles Of Information Design To Help Parents Accept Babies With Down Syndrome, Anita Eradla Jan 2006

Applying Principles Of Information Design To Help Parents Accept Babies With Down Syndrome, Anita Eradla

Theses and Dissertations

My creative project is a system of resource materials designed for parents and expecting parents to promote acceptance of babies with Down syndrome. This project is also a study of information architecture and icon development, and an opportunity to study the universal and emotive qualities of an iconic system.

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Determinants Of Dating Violence Among Youth In The U.S., Candace Hamm Jan 2006

Determinants Of Dating Violence Among Youth In The U.S., Candace Hamm

Theses and Dissertations

Background: Physical Dating Violence (PDV) victimization is a major public health concern among adolescents in the United States. Research has shown that determinants of PDV victimization are different for male and female adolescents. However, inconsistent findings entail that further research needs to be done using a representative sample of male and female adolescents.Objective: To identify gender-specific determinants of PDV victimization utilizing a nationally representative sample of high school adolescents.Methods: Data from the 2005 National Youth Risk Behavior Survey was used for this analysis. The study population included 6.951 male and 6,807 female students in grades 9 through 12. Bivariate and …

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Healing Interior: Using Eastern Design Principles In Hotel Design, Yunju Lee Koh Jan 2006

Healing Interior: Using Eastern Design Principles In Hotel Design, Yunju Lee Koh

Theses and Dissertations

The main goal of this thesis is to explore how interior spaces in hotel designs can provide a less stressful environment and promote health and harmony by using Feng Shui Principles. It will first discuss the principles of Feng Shui and general hotel design, and then move on to demonstrate how the application of Feng Shui principles can be used to create a hotel environment that encourages health and harmony in its occupants. This project will demonstrate principles that not only can be applied to hotel space, but also can be practiced in any other interior space. This thesis, therefore, …

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Pharmacological Studies Of Nicotine And Galantamine Effects On Age Associated Memory Impairment And The Neurotrophic System In Aged Female Rats, Kristen L. French Jan 2006

Pharmacological Studies Of Nicotine And Galantamine Effects On Age Associated Memory Impairment And The Neurotrophic System In Aged Female Rats, Kristen L. French

MUSC Theses and Dissertations

Nicotine and Galantamine were studied for their pharmacological effects on age associated memory impairment (AAMI) and the neurotrophin system in the aged female F344 rat. Nicotine was found to have dose dependent effects on cognition in the 24 month old rat. A low dose of nicotine improved both working and reference memory (WM, RM) performance on the water radial arm maze and also improved the ability of aged rats to handle an increasing WM load. A high dose did not improve WM and caused deficits in RM, and high cotinine levels in these subjects correlated with worse performance. Nicotine treatment …

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Engaging Diversity At An Australian University: Chinese International Students' Perceptions Of Their Social Experience While Studying In Australia, James Cross Jan 2006

Engaging Diversity At An Australian University: Chinese International Students' Perceptions Of Their Social Experience While Studying In Australia, James Cross

EDU-COM International Conference

Increasing diversity of student populations at Australian universities has raised research attention on how international students are coping with their academic and social life. A research project conducted with Chinese students studying at Edith Cowan University (ECU) in Western Australia in 2005 revealed various cultural and equity issues which impact on the Chinese international students' academic and social experiences in Australia. This paper focuses on the social aspects of the findings from this study. It was found that most Chinese students reported poor social life and interaction with local and other international students on and off campus. Developing friendship with …

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The Developments In Paramedical Science And The Implications Of National And International Accreditation And Registration In Alliance With Ambulance Authorities, Barry Gibson, Richard Brightwell Jan 2006

The Developments In Paramedical Science And The Implications Of National And International Accreditation And Registration In Alliance With Ambulance Authorities, Barry Gibson, Richard Brightwell

EDU-COM International Conference

The School of Exercise, Biomedical and Health Sciences at Edith Cowan University established a new Bachelor of Science (Paramedical Science) degree in 2004. The program is a joint initiative between Edith Cowan University and St. John Ambulance and is the only Paramedical degree being taught within Western Australia. In preparing the graduates to work in the profession as qualified paramedics, it was essential to integrate the theoretical content taught by both the university and the ambulance corporation with significant practical experiences being delivered in the ambulance and hospital environments. The implications for this type of arrangement have been far reaching, …

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Initiating Community Engagement For Enhancing Preservice Teacher Education, Peter Hudson, Sue Hudson Jan 2006

Initiating Community Engagement For Enhancing Preservice Teacher Education, Peter Hudson, Sue Hudson

EDU-COM International Conference

Facilitating community engagement in education is promoted and emphasised in university policies and strategic plans. How can a university facilitate innovations to develop collaborative partnerships with its community? This paper presents leadership processes for initiating community engagement with an Australian university and highlights examples of innovations in Science Education for Sustainable Living (SESL) with preservice teachers‘ reflections on their teaching practices. Data collection included observations of practice, interviews, minutes of meetings, and written correspondence with a wide range of participants (i.e., senior QUT staff, lecturers, preservice teachers, principals, school executives and teachers, and other community members). A four-step process for …

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An Ontology Based Approach To The Integration Of Heterogeneous Information Systems Supporting Integrated Provincial Administration In Khon Kaen, Thailand, Malee Kabmala, Lampang Manmart, Chaiyaporn Chirathamjaree Jan 2006

An Ontology Based Approach To The Integration Of Heterogeneous Information Systems Supporting Integrated Provincial Administration In Khon Kaen, Thailand, Malee Kabmala, Lampang Manmart, Chaiyaporn Chirathamjaree

EDU-COM International Conference

Information systems are a necessity to the administration of organizations. In a recent reform to the Thai administration, the governor of each province is entrusted with the full responsibility for the strategic planning and execution of the Integrated Provincial Administration (IPA). This presents a big challenge and many difficult problems for a potentially fast growing, both economically and demographically, province, such as Khon Kaen. To provide the administrator of the province with reliable and up to date information, the Provincial Operation Centre (POC) has been set up and assigned the task of collecting all required information from disparate information systems, …

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Building Empowered Students: The Perennial Challenge For University Teachers, Patsy Paxton Jan 2006

Building Empowered Students: The Perennial Challenge For University Teachers, Patsy Paxton

EDU-COM International Conference

This paper contends that if higher education is to be relevant, then the curriculum must incorporate generic, transferable lifeskills (also referred to as ‗generic graduate attributes‘) in addition to the regular subject content of their specific discipline or programme. There is a general consensus among educationists and business people alike that much of what students learn today won't be true five years from now. However, if they are taught how to take responsibility for their own ideas, how to think and communicate a problem through and how to have a positive can-do attitude, then no matter what subject matter is …

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Community-Based English Course In Local Perspectives, Ratchaporn Rattanaphumma Jan 2006

Community-Based English Course In Local Perspectives, Ratchaporn Rattanaphumma

EDU-COM International Conference

The paper aims to investigate how a community-based English language course can assist learners in the development of language skills and local cultural knowledge. The samples were 17 undergraduate English major students in Faculty of Education, Rajabhat Rajanagarindra University. The qualitative method was mainly employed in the study. Data were collected through unstructured interviews and participant observation. The strategies used in data analysis were analytic induction and typological analysis. The findings revealed that motivation, experiential learning, and collaboration played significant roles in the process of language and culture learning. The paper also discusses the significance of local perspectives when the …

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