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2006

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Animal Health Matters, David H. Zeman Nov 2006

Animal Health Matters, David H. Zeman

Animal Health MATTERS Newsletter

Head/Director's Message [Page] 1-Animal Health Surveillance Demands Continue to Grow Diagnostic News [Page] 1- Combined North American/European-like / LV “Multi-PRRSV Real-Time PCR Assay [Page] 2- Antemortem Diagnostics for Bovine Respiratory Disease: Obtaining Bronchoalveolar Lavage Samples [Page] 2- Holiday Hours Extension News [Page] 3- Tularemia Cases Diagnosed at SDSU ADRDL: September 2005 – October 2006 [Page] 4- Process Verified Programs (PVP’s) Available to SD Calf Producers [Page] 5- Pieces and Parts [Page] 8- Calendar of Events

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Early Childhood Education : Pathways To Quality And Equity For All Children, Alison Elliott Nov 2006

Early Childhood Education : Pathways To Quality And Equity For All Children, Alison Elliott

Australian Education Review

AER 50 calls for a coherent, long-term national action plan and timeline to develop and implement an integrated, well-funded, regulated and managed system of early childhood education and care with clear goals, priorities and outcomes. The review describes the current provision of early childhood services in Australia and examines relevant policy. It also provides an overview of the early childhood education research, in Australia and internationally, and uses this body of work to identify and illuminate the central issues.

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The Impact Of High Density Lipoprotein Cholesterol On Five-Year Mortality In Older Adults, Lisa Millman Nov 2006

The Impact Of High Density Lipoprotein Cholesterol On Five-Year Mortality In Older Adults, Lisa Millman

Yale Medicine Thesis Digital Library

The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III) guidelines have defined a high density lipoprotein cholesterol (HDL-C) of <50 mg/dL in women and <40 mg/dL in men as a risk factor for cardiovascular disease. Our research aim was to examine the relationship between untreated HDL-C levels below this recommended level on five year cardiovascular, stroke, and all-cause mortality in adults over 71 years of age. The Established Populations for Epidemiologic Studies of the Elderly (EPESE) is a prospective cohort study of community dwelling adults over 65 years of age in East Boston, MA; Iowa and Washington Counties, IA; New Haven, CT; and Durham, NC. The National Institutes of Aging (NIA) started EPESE to study health, social, psychological, and economic aspects of older adults lives through extensive annual interviews. The EPESE dataset is further enriched by serum measures including low-density lipoprotein cholesterol (LDL-C), HDL-C, total cholesterol, triglycerides, glucose, BUN and creatinine, which were obtained at the sixth annual follow-up interview. Our primary outcome was all-cause mortality with secondary mortality outcomes of acute myocardial infarction (AMI), coronary artery disease (CAD) not AMI, and congestive heart failure (CHF). The mean age of our cohort was 78.7 years with the majority being female (63.86%), white (88.15%), and married (52.80%). Just over half (52.07%) of our cohort met the criteria for low HDL-C as defined by ATP III. Chi square and Fisher exact test were used to compare demographics (age, gender, race, marital status, education), clinical variables (history of MI, cancer, diabetes, angina, smoking, alcohol use), and functional variables (activities of daily living, gross mobility, cognitive status) at baseline and five year follow-up. Cox proportional hazard models were created using a step-wise approach to assess the impact of low HDL-C on mortality. Low HDL-C was not significantly associated with crude all-cause (P= .413), AMI (P= .473), CHF (P= .259), and stroke (P= .345) mortality. HDL-C was significantly associated with unadjusted CAD (P= .033) mortality. However, after adjustment for demographics, clinical, and functional variables as well as the other blood values all outlined above, HDL-C was not associated with five year all-cause, AMI, CAD, CHF or stroke mortality with adjusted hazard ratios of (HR=1.03, 95% CI 0.90-1.18), (HR=1.09, 95% CI 0.70-1.71), (HR=1.33, 95% CI 0.91-1.92), (HR=1.07, 95% CI 0.63-1.81) and (HR=0.80, 95% CI 0.51-1.27) respectively. In older community dwelling adults enrolled in EPESE, low HDL-C levels as stratified by current recommended guidelines (<50 mg/dL in women and <40 mg/dL in men) were not associated with increased risk of five-year cardiovascular, stroke or all-cause mortality. HDL-C alone may have minimal effect on future longevity in older adults due to competing risk and co-morbid conditions. Further studies are required to determine whether the movement toward more aggressive lipid profile interventions specifically to raise HDL-C in older adults would prove beneficial in this growing segment of our population.

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Quality Of Life In Macular Degeneration Between Photodynamic Therapy And Pegaptanib Treatment Groups, Sara Nayeem Nov 2006

Quality Of Life In Macular Degeneration Between Photodynamic Therapy And Pegaptanib Treatment Groups, Sara Nayeem

Yale Medicine Thesis Digital Library

The purpose of this study was to examine quality of life (QOL) in age-related macular degeneration (AMD), particularly across photodynamic therapy (PDT) and pegaptanib sodium injection treatment groups. Patients with AMD were either mailed or were administered in person a modified version of the Visual Function Questionnaire (VFQ-25). Subgroup analysis of the VFQ-25 was performed per NEI prescribed algorithms and additional analyses regarding questions on treatment side effects were also performed. A two-tailed student t-test and mean were calculated for each treatment group and correlations between visual acuity and subgroup outcomes were calculated. Correlations between the subgroup and treatment-related subgroup …

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Effect Of Soy Isoflavone Protein And Soy Lecithin On Endothelial Function In Healthy Postmenopausal Women, Mary Pearson Nov 2006

Effect Of Soy Isoflavone Protein And Soy Lecithin On Endothelial Function In Healthy Postmenopausal Women, Mary Pearson

Yale Medicine Thesis Digital Library

The purpose of this study was to assess the effects of soy isoflavone protein concentrate and soy lecithin on endothelial function measured as flow mediated dilation (FMD) of the brachial artery in healthy postmenopausal women. In this randomized, double-blind, placebo controlled crossover trial, twenty-five subjects (mean age 61 years; BMI 25.46 kg/m2) were recruited from the general population of southwestern Connecticut. Subjects underwent endothelial function testing using high frequency ultrasound at baseline and following 4 weeks of each randomly assigned treatment with intervening 4-week washout periods. Treatment assignment included: soy isoflavone protein (SP, 25gm/day) or soy lecithin (SL, 20gm/day) alone …

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Social Influences On Academic Motivation In Early Elementary School Students, Jenli Waters Nov 2006

Social Influences On Academic Motivation In Early Elementary School Students, Jenli Waters

Yale Medicine Thesis Digital Library

The goal of this research is to identify correlations between academic intrinsic motivation and exposures to academic activities within the home acknowledged by young children (5 to 8 years old). This study hopes to clarify relationship between academic intrinsic motivation and exposure to positive role modeling of academic activities in young children. Much of the data was collected by interview-style surveys conducted with a sample of 18 boys and girls of ages between 5 and 8 years. The Child-Reported Home Reading and Math Exposure Questionnaire (HEQ) was developed by the author for this study to assess the extent to which …

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Identification And Role Of The Mta1 Complex In Small Intestinal Carcinoids Malignancy, Michelle Zikusoka Nov 2006

Identification And Role Of The Mta1 Complex In Small Intestinal Carcinoids Malignancy, Michelle Zikusoka

Yale Medicine Thesis Digital Library

Background: Carcinoid tumors are rare tumors that, despite advances in medical research, have remained enigmatic. Carcinoid tumors can be categorized using gross pathological, histological, and biochemical profiles. While of some utility, this classification method fails to enable accurate determination of malignant potential. Incorporation of molecular analysis of carcinoids will create a paradigm shift in classification. To this end, high throughput technologies such as Quantitative RT PCR, Tissue Microarray, and cDNA Microarray will facilitate such changes. In our investigations, cDNA microarray analysis identified Metastasis-associated protein-1 (MTA1), Histone Deacetylase 2 (HDAC2), and aberrant transcriptional regulation as factors involved in the molecular pathogenesis …

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The Effects Of Posttraumatic Stress Disorder On Pregnancy Outcomes, Shari Rogal Nov 2006

The Effects Of Posttraumatic Stress Disorder On Pregnancy Outcomes, Shari Rogal

Yale Medicine Thesis Digital Library

The purpose of this study was to determine the effect of posttraumatic stress disorder (PTSD), diagnosed prospectively during pregnancy, on the occurrence of low birthweight (<2500 grams) and preterm delivery (<37 weeks gestational age). A cohort of 1362 women was recruited from prenatal care visits and screened for depression, panic disorder, posttraumatic stress disorder, and substance use. Current episodes of PTSD were assessed using the MINI International Neuropsychiatric Interview. Pregnancy outcomes were abstracted from hospital records after delivery, and the data were analyzed using logistic regression. Two hundred sixty two women (33%) were lost to follow-up due to unavailable medical records, leaving 1100 women in the final analyses. Among these 1100 women, 31 (3%) were found to have PTSD during pregnancy. Substance use in pregnancy, panic disorder, major and minor depressive disorders, and prior preterm delivery were significantly associated with PTSD in the sample, while age, language spoken, and race were not. Low birthweight (LBW) was present in 6.5% of sampled women and was not significantly associated with a diagnosis of PTSD in pregnancy when adjusting for potential confounders. However, LBW was significantly associated with minor depressive disorder OR= 1.82 (CI=1.01, 3.29). Preterm delivery occurred in 7.0% of those without and 16.1% of those with PTSD (p=0.055). Because prior preterm delivery data were not available for 33% of women with PTSD, this variable was included only in secondary analyses. However, the association between PTSD and preterm delivery depended on this variable, with OR= 2.82 (0.95, 8.38) before controlling for prior preterm delivery and OR=3.35 (1.04, 10.85) after controlling for prior preterm delivery. These data suggest that a possible association of PTSD and preterm delivery was limited by the low rates of PTSD in this cohort and the inability to control for all confounders. Taken together, these findings provide limited support for the hypothesized association between PTSD and preterm delivery and no support for an association of PTSD with LBW.

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The Anchor, Volume 120.09: November 15, 2006, Hope College Nov 2006

The Anchor, Volume 120.09: November 15, 2006, Hope College

The Anchor: 2006

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

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The Effects Of Menstrual Phase On The Response Of Cutaneous Microvasculature, Margaret Rose Nov 2006

The Effects Of Menstrual Phase On The Response Of Cutaneous Microvasculature, Margaret Rose

Yale Medicine Thesis Digital Library

Estrogen is well-known to be protective against cardiovascular disease in women. In addition to improving lipid metabolism, it also decreases vascular resistance and enhances vascular reflexes, thereby improving vasomotor stability and increasing the arterial capacity for dilatation. Laser Doppler flowmetry (LDF) has demonstrated these changes in research trials, and is emerging as having potential application in many clinical and surgical situations. In this study, our aim was to examine the impact of estrogen upon baseline blood flow as well as the response to vasodilatory interventions and to further evaluate the utility of laser Doppler as a clinical non-invasive measurement of …

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Mother Knows Best: Maternal Experience And Choice Of Infant Sleep Position, Meghan Lane Nov 2006

Mother Knows Best: Maternal Experience And Choice Of Infant Sleep Position, Meghan Lane

Yale Medicine Thesis Digital Library

Purpose: The purpose of this project was to examine the associations between maternal child-rearing experience, choice of infant sleeping position, and the source, nature and trust of advice received about infant sleeping position in a high-risk, primarily African-American population. Background: The number of deaths attributed to Sudden Infant Death Syndrome (SIDS) has decreased since the initiation of the Back to Sleep campaign in 1994. Although this change has benefited all ethnic groups, African-American infants are still twice as likely to succumb to SIDS as Caucasian infants. Design/Methods: We conducted 668 face-to-face standardized interviews with mothers of infants in Connecticut, Georgia …

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Mexico's Health Secretary Loses To Hong Kong Doctor In Bid To Lead Who, Ladb Staff Nov 2006

Mexico's Health Secretary Loses To Hong Kong Doctor In Bid To Lead Who, Ladb Staff

SourceMex

No abstract provided.

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Campus Chronicle, Jeni Gieseke, Alex Middleton, Jeremy Harmsen, Megan Lyon, Jesi Landwier, Malina Doke, Malin Cheney Nov 2006

Campus Chronicle, Jeni Gieseke, Alex Middleton, Jeremy Harmsen, Megan Lyon, Jesi Landwier, Malina Doke, Malin Cheney

Campus Chronicle

No abstract provided.

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The Winonan, Winona State University Nov 2006

The Winonan, Winona State University

The Winonan - 2000s

No abstract provided.

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Sin Nombre Viral Rna Load In Patients With The Hantavirus Cardiopulmonary Syndrome, Ruobing Xiao, Brian Hjelle Nov 2006

Sin Nombre Viral Rna Load In Patients With The Hantavirus Cardiopulmonary Syndrome, Ruobing Xiao, Brian Hjelle

Undergraduate Medical Student Research

To address the role of viral load in pathogenesis in patients with hantavirus cardiopulmonary syndrome (HCPS), we quantified Sin Nombre virus S segment viral RNA in plasma samples from 27 acutely-ill patients. For six patients we examined viral load in matched plasma, urine, and/or tracheal aspirate throughout the time when patients were in intensive care. Peak titers in plasma reached 1.8x106 copies/ml; none had viral RNA in urine. Titers in tracheal aspirates did not exceed 8x104/ml. We found a statistically significant association (P< 0.005) between plasma viral RNA levels at admission and the severity of disease. Of those with plasma viral RNA titers above the threshold for assay sensitivity (5000 copies/ml), those with mild-moderate and severe disease had an average of 27,800 and 438,545 copies/ml, respectively. These results suggest that patients with high viral loads on admission are more likely to have severe disease.

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Montana Kaimin, November 15, 2006, Students Of The University Of Montana, Missoula Nov 2006

Montana Kaimin, November 15, 2006, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula. Page 3 is missing.

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The Narrative Of Lieutenant Colonel L.R. Stacy, C.B., Bengal Native Infantry, Whilst In The Brahooe Camp, Inducing The Submission Of Nasseer Khan, Only Son Of The Late Meer Meerab Khan, Khan Of Khelat; And In The Subsequent Operations Of General Nott's Army In Its March To And Its Return From Kabul. (1884) , Lewis Robert Stacy Nov 2006

The Narrative Of Lieutenant Colonel L.R. Stacy, C.B., Bengal Native Infantry, Whilst In The Brahooe Camp, Inducing The Submission Of Nasseer Khan, Only Son Of The Late Meer Meerab Khan, Khan Of Khelat; And In The Subsequent Operations Of General Nott's Army In Its March To And Its Return From Kabul. (1884) , Lewis Robert Stacy

Digitized Afghanistan Materials in English from the Arthur Paul Afghanistan Collection

19th century history of Afghanistan and the relationship between Afghanistan and Britain.

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November 29th 2006, Hispanic News Nov 2006

November 29th 2006, Hispanic News

Inland Empire Hispanic News

No abstract provided.

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November 15th 2006, Hispanic News Nov 2006

November 15th 2006, Hispanic News

Inland Empire Hispanic News

No abstract provided.

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Large, Single Institution Review Of Prognostic Factors In Oligodendroglioma, Heather Mckee Nov 2006

Large, Single Institution Review Of Prognostic Factors In Oligodendroglioma, Heather Mckee

Yale Medicine Thesis Digital Library

Studies have demonstrated an association between loss of heterozygosity on chromosome 1p and chromosome 19q in oligodendrogliomas with both chemosensitivity and prolonged survival. This represents the first time genetic mutations have been utilized to guide clinical decision making. Studies have also found these genetic mutations to be associated with magnetic resonance imaging (MRI) features including indistinct tumor borders on T1-weighted imaging, susceptibility effect, and mixed signal intensity. However, no study has yet demonstrated an association between imaging features and survival. We seek to confirm the clinical utility of known prognostic factors such as age and tumor grade while investigating the …

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Mega-Doses Of L-Ascorbic Acid Alter The Antineoplastic Effects Of Ionizing Radiation In Emt6 Cells In Vitro, Karina Lund Nov 2006

Mega-Doses Of L-Ascorbic Acid Alter The Antineoplastic Effects Of Ionizing Radiation In Emt6 Cells In Vitro, Karina Lund

Yale Medicine Thesis Digital Library

Despite the common usage of high-dose vitamin C among breast cancer patients, the published medical literature is not in agreement as to how mega-dose vitamin C may interact with conventional therapy to affect clinical outcomes. The purpose of this study was to investigate the interaction of mega-dose vitamin C with radiation therapy and with doxorubicin in the treatment of breast cancer. Cultures of EMT6 mouse mammary tumor cells were treated concurrently with varying dose of vitamin C and either radiation or doxorubicin. A clonogenic assay was then performed to determine the surviving fraction of the cells. The surviving fractions of …

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Prevalence And Predictors Of Chronic Liver Disease In An Urban Hiv Population, Sunanda Pejavar Nov 2006

Prevalence And Predictors Of Chronic Liver Disease In An Urban Hiv Population, Sunanda Pejavar

Yale Medicine Thesis Digital Library

Chronic liver disease (CLD) is a leading cause of morbidity and mortality in HIV-infected individuals. The purposes of this study were to determine the prevalence and etiologies of CLD in an urban HIV-infected population and to identify CLD risk factors. We conducted a retrospective chart review of 799 HIV-infected patients seen at four New Haven health centers from 2002 to 2003. We applied the New Haven County Liver Study definition to identify patients with CLD. 65% were male, 44% were African American, and 23% were of Hispanic ethnicity. The mean age was 45 years. 30% had a history of alcohol …

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The Role Of Ectopic Lymphoid Tissue In Allograft Rejection, Michael Reel Nov 2006

The Role Of Ectopic Lymphoid Tissue In Allograft Rejection, Michael Reel

Yale Medicine Thesis Digital Library

The location of the immunologic response to an allograft is not known with certainty. However, organized collections of T cells, B cells and antigen presenting cells have been found in peripheral tissue, in close proximity to organs undergoing rejection. It is hypothesized that this tertiary lymphoid tissue may be a location in which activation of lymphocytes can occur, leading to rejection of an allograft. We report here that in a splenectomized aly/aly mouse, which is devoid of secondary lymphoid organs and will normally fail to reject an allograft, the presence of tertiary lymphoid organs is associated with graft rejection. We …

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Routine Anal Cytology Screening For Anal Squamous Intraepithelial Lesions In An Ethnically Diverse Urban Hiv Clinic, Hyman Scott Nov 2006

Routine Anal Cytology Screening For Anal Squamous Intraepithelial Lesions In An Ethnically Diverse Urban Hiv Clinic, Hyman Scott

Yale Medicine Thesis Digital Library

Anal cancer, like cervical cancer, is associated with Human Papillomavirus (HPV) infection. HIV+ patients have 38-60 fold increased risk of anal cancer compared to HIV- patients prompting many to suggest routine screening given the success of cervical Pap screening. Our goal is to describe our experience with routine anal Pap screening, determine which patients are most likely to have abnormal results, if anal disease on physical exam is predictive of cytology, and correlate cytology with histology findings. Charts of all patients with an anal Pap followed at the Hospital of Saint Raphael HIV Clinic were reviewed. Demographics, immune status, sexually …

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Prevalence Of Pain In The Medical Intensive Care Unit, Jennifer Smith Nov 2006

Prevalence Of Pain In The Medical Intensive Care Unit, Jennifer Smith

Yale Medicine Thesis Digital Library

N/A (long introduction)

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Search For The Basolateral Potassium Channel In The Shark Rectal Gland: Functional And Molecular Identification Of A Task-1 Channel Coupled To Chloride Secretion, Conner Telles Nov 2006

Search For The Basolateral Potassium Channel In The Shark Rectal Gland: Functional And Molecular Identification Of A Task-1 Channel Coupled To Chloride Secretion, Conner Telles

Yale Medicine Thesis Digital Library

In the shark rectal gland (SRG), apical Cl- secretion through CFTR channels is tightly coupled to a basolateral K+ conductance. The identity of this K+ conductive pathway is unknown. Studies were performed in the isolated perfused SRG with 16 K+ channel inhibitors at their IC50 and with acidic perfusate. During maximal chloride secretion stimulated by forskolin and IBMX, secretion was inhibited >90% by barium chloride, a non-selective inhibitor of K+ channels. Specific inhibitors of calcium sensitive, voltage sensitive, ATP sensitive, and inward rectifying K+ channels had no effect on chloride secretion. The inhibitors quinidine, quinine, bupivicaine, anandamide, and low perfusate …

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Overcoming Barriers To Enrolling Minorities In Medical Research: What Does The Evidence Say?, Stacy Uybico Nov 2006

Overcoming Barriers To Enrolling Minorities In Medical Research: What Does The Evidence Say?, Stacy Uybico

Yale Medicine Thesis Digital Library

Background: Despite the pervasive underrepresentation of minorities in health research studies, little is known about strategies that aim to increase minority enrollment in research. Purpose: The purpose of this study was to identify whether elder African American and Latinos were more likely to refuse research participation, identify tangible and specific incentives to improve research participation in this population, and to review the successes and data reporting of recruitment interventions attempted on diverse populations at large, including the non-elderly. Methods: We conducted a review of Yale OAIC studies to determine minority vs. non-minority research enrollment rates, interviewed key informants about likely …

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The Effect Of General Anesthesia On Acupuncture: A Functional Mri Study, Dana Weiss Nov 2006

The Effect Of General Anesthesia On Acupuncture: A Functional Mri Study, Dana Weiss

Yale Medicine Thesis Digital Library

We performed a study to examine brain activity as assessed by functional-MRI when acupuncture is administered to awake volunteers as compared to acupuncture administered to volunteers under general anesthesia. Healthy, acupuncture-naive volunteers were recruited for this cross-over study. Volunteers underwent two experimental sessions that included a sequence of 4-20 seconds of on and off manual acupuncture stimulation for a period of 3 minutes while awake and while under propofol general anesthesia. The acupuncture intervention was performed at left stomach 36. General anesthesia was induced and maintained with propofol. BOLD signal images were obtained in a 1.5 T MRI scanner in …

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Minutes, Staff Council Meeting, November 15, 2006, University Of South Florida St. Petersburg. Staff Council Nov 2006

Minutes, Staff Council Meeting, November 15, 2006, University Of South Florida St. Petersburg. Staff Council

Staff Council

Minutes from the November 15, 2006, meeting of the University of South Florida St. Petersburg Staff Council.

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The Lumberjack, November 15, 2006 Nov 2006

The Lumberjack, November 15, 2006

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

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