Digital Commons Network^™

Impacts Of A Recurrent Resuspension Event And Variable Phytoplankton Community Composition On Remote Sensing Reflectance, Trisha Bergmann, Gary Fahnenstiel, Steven Lohrenz, David Millie, Oscar Schofield

Faculty Publications

In order to characterize the impact of turbidity plumes on optical and biological dynamics, a suite of environmental parameters were measured in southern Lake Michigan during the springtime recurrent sediment plume. In-water measurements of inherent optical properties (IOPs) were entered into the Hydrolight 4.2 radiative transfer model and the output was compared with measured apparent optical properties (AOPs) across a wide range of optical conditions. Hydrolight output and measured underwater light fields were then used to clarify the effects of the sediment plume on primary production, phytoplankton community composition, and nearshore remote sensing ocean color algorithms. Our results show that …

The Acquisition Of The English Present Perfect By A Speaker Of Brazilian Portuguese, Eleomarques Rocha

LSU New Orleans Theses and Dissertations

This study contributes to the debate about the importance of focus on form to adult second language acquisition with an investigation of a Portuguese-speaking adult's acquisition of English present perfect from a historical, correlational, and qualitative viewpoint. Using a husband-wife interaction in the L1, it investigates whether explicit grammar instruction and error correction can lead to automatic production. The focus of the study, the distinction between L1 present simple and L2 present perfect, is contrasted with a control distinction: L1 stative and L2 progressive. The importance of these distinctions is that both are semantically challenging for the L2 acquirer; therefore, …

Multipitch Analysis And Tracking For Automatic Music Transcription, Richard Baumgartner

LSU New Orleans Theses and Dissertations

Music has always played a large role in human life. The technology behind the art has progressed and grown over time in many areas, for instance the instruments themselves, the recording equipment used in studios, and the reproduction through digital signal processing. One facet of music that has seen very little attention over time is the ability to transcribe audio files into musical notation. In this thesis, a method of multipitch analysis is used to track multiple simultaneous notes through time in an audio music file. The analysis method is based on autocorrelation and a specialized peak pruning method to …

Sensitivity To Dopamine D1/D2 Receptor Stimulation In Mice Lacking Connexin-32 Or Connexin-36, James Mckenna

LSU New Orleans Theses and Dissertations

Previous work has shown D1/D2 requisite synergism can still occur in the striatum in the absence of action potentials. Some nonclassical communication such as gap junctions may be allowing the segregated dopamine (DA) receptors to interact to produce stereotyped motor activity. Connexin-32 (Cx32) and connexin-36 (Cx36) were targeted for study due to their abundance in neural tissues and presence in the striatum. Mice lacking either the Cx32 or Cx36 gene and their respective wildtype littermates were compared on a climbing behavior task used to gauge their dopaminergic activity after receiving either saline, D1 agonist, D2 agonist, or both D1 and …

Combined Anaerobic/Aerobic Treatment For Municipal Wastewater, Harold Padron

LSU New Orleans Theses and Dissertations

Implementation of combined anaerobic/aerobic processes for wastewater treatment has been shown feasible, especially for industrial wastewaters with high concentration of organics. However, the utilization of this type of technology for treating wastewaters with low content of organic matter, such as domestic sewage is quite recent, and very limited information is available regarding the topic. Recent investigations have demonstrated that it is feasible to utilize a combined technology composed of anaerobic pretreatment followed by an aerobic post-treatment to efficiently treat municipal wastewater. This research is a continuation of previous investigations about the feasibility of using an anaerobic fluidized bed reactor-aerated solids …

The Design And Synthesis Of Novel Barbiturates Of Pharmaceutical Interest, Donna Neumann

LSU New Orleans Theses and Dissertations

Barbituric acids have been historically classified as compounds that act on the central nervous system, and as such provide therapeutic uses as anxiolytics, sedatives, hypnotics, and anticonvulsants. Recent investigations of barbituric acid derivatives have provided scientists with information that barbituric acids may have applications in antibacterial, anti-chlamydial, anti-viral, as well as anti-cancer treatments. Additionally, recent literature accounts have indicated that barbituric acid derivatives may also act as immune modulators. The recent explorations of barbiturates and their potential anti-cancer and immune modulating properties are the subject of this work. Novel synthetic approaches to the development of new barbituric acid derivatives were …

Reproducible Research: A Bioinformatics Case Study, Robert Gentleman

Bioconductor Project Working Papers

While scientific research and the methodologies involved have gone through substantial technological evolution the technology involved in the publication of the results of these endeavors has remained relatively stagnant. Publication is largely done in the same manner today as it was fifty years ago. Many journals have adopted electronic formats, however, their orientation and style is little different from a printed document. The documents tend to be static and take little advantage of computational resources that might be available. Recent work, Gentleman and Temple Lang (2004), suggests a methodology and basic infrastructure that can be used to publish documents in …

Western News, May 20, 2004, Western Michigan University

Western News (1972-2018)

Story highlights: Thomas Kent is new dean of the College of Arts and Sciences; Fred Decker retires; obituaries for Robert Harmon and E. L. Marietta; On Campus with Holly Matthews.

Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for May 20, 2004

Spectator 2004-05-20, Editors Of The Spectator

The Spectator

No abstract provided.

New Nonthermal Filaments At The Galactic Center: Are They Tracing A Globally Ordered Magnetic Field?, Ted La Rosa, Michael E. Nord, Joseph W. Lazlo, Namir E. Kassim

Faculty Articles

New high-resolution, wide-field 90 cm VLA observations of the Galactic center (GC) region by Nord and coworkers have revealed 20 nonthermal filament (NTF) candidates. We report 6 cm polarization observations of six of these. All of the candidates have the expected NTF morphology, and two show extended polarization, confirming their identification as NTFs. One of the new NTFs appears to be part of a system of NTFs located in the Sgr B region, 64 pc in projection north of Sgr A. These filaments cross the Galactic plane with an orientation similar to the filaments in the Galactic center radio arc. …

Multiple Signal Transducers And Activators Of Transcription Are Induced By Ebv Lmp-1, Luwen Zhang, Ke Hong, Jun Zhang, Joseph S. Pagano

Nebraska Center for Virology: Faculty Publications

Epstein-Barr virus (EBV) latent membrane protein 1 (LMP-1) is required for EBV immortalization of primary B cells in vitro. Signal transducers and activators of transcription (STATs) play a pivotal role in the initiation and maintenance of certain cancers. STAT proteins, especially STAT-1, -3, and -5, are persistently tyrosine phosphorylated or activated in many cancers. We show here that EBV-infected type III latency cells, in which the EBV oncoprotein, LMP-1 is expressed, express high levels of four STATs (STAT-1, -2, -3, and -5A) and that LMP-1 is responsible for the induction of three (STAT-1, -2, and -3). In addition, the C-terminal …

Biomedical And Psychosocial Determinants Of Problematic Birth Outcomes, Charlan Day Kroelinger

USF Tampa Graduate Theses and Dissertations

The primary objective of this study was to evaluate the associations between psychosocial stressors, urine sugar levels, and subsequent birth outcomes, specifically high birth weight babies and Caesarean section births. In a prospective cohort study, 506 Black and White women of childbearing age were followed for the duration of one pregnancy in Tuscaloosa and Mobile counties in Alabama from 1990 to 2001. Participants were interviewed twice throughout pregnancy, during the first and third trimesters, respectively, and birth outcome data were collected via medical chart reviews. Six percent (6.1%) of the women in the sample had a high birth weight baby, …

The Developing Nucleus Accumbens Septi: Susceptibility To Alcohol’S Effects, Rex Montgomery Philpot

USF Tampa Graduate Theses and Dissertations

The mesolimbic dopamine (DA) system has been implicated in providing the basis of pleasure, guiding the general mechanism of reinforcement as well as motivation. Support for these roles have grown from neurochemical research in the field of addiction. It is now well known that DA activity increases in the nucleus accumbens septi (NAcc) with exposure to addictive substances. Moreover, pharmacological manipulation of this system produces predictable changes in the administration of drugs of abuse, as well as natural reinforcers. This system is responsive to natural reinforcers and addiction may be the transference of routine mesolimbic function to environmental stimuli predictive …

Intellectual Property Protection In Philippine Agriculture: A Developmental Perspective, Salvador B. Belaro Jr.

Cornell Law School J.D. Student Research Papers

This paper is premised on the debate on whether intellectual property protection furthers economic development in developing countries. One view is that more is better, arguing that intellectual property rights trigger research and technological advancement. The other view is that more means not better, but worse. Advocates of this view claim that developing countries, being "second comers" in a world where developed countries got a head start in development are confronted with rules imposed by the "first comers", intellectual property rules included, which are of course, designed by the latter to serve their interests

This note suggests two general approaches …

Evaluating The Contributions Of Desolvation And Base-Stacking During Translesion Dna Synthesis, Xuemei Zhang, Irene Lee, Anthony J. Berdis

Chemistry Faculty Publications

DNA polymerases catalyze the insertion of a nucleoside triphosphate into the growing polymer chain using the template strand as a guide. Numerous factors such as hydrogen bonding interactions, base-stacking contributions, and desolvation play important roles in controlling the efficiency and fidelity of this process. We previously demonstrated that 5-nitro-indolyl-2′-deoxyriboside triphosphate, a non-natural nucleobase with enhanced base-stacking properties, was more efficiently inserted opposite a non-templating DNA lesion compared to natural templating nucleobases (E. Z. Reineks and A. J. Berdis, Biochemistry, 2004, 43, 393–404). The catalytic enhancement was proposed to reflect increased base-stacking interactions of the non-natural nucleobase with the polymerase and …

May 19, 2004 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

May 19, 2004 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

Ke Alaka'i, Vol. 69, No. 16 (2004-05-19), Brigham Young University Hawaii

Ke Alaka'i

No abstract provided.

N9 Alkylation And Glycosylation Of Purines; A Practical Synthesis Of 2-Chloro-2'-Deoxyadenosine, Minghong Zhong

Theses and Dissertations

(a) The Robins reagent [2-acetamido-6-O-(diphenylcarbamoyl)purine] was utilized for glycosylation under Lewis acid conditions. Regioselectivity of glycosylation depends on the glycosyl donor and its 2-O- or 2-N-protecting group. Regioselective N9 glycosylation of 2-acetamido-6-O-(diphenylcarbamoyl)purine with problematic glucosamine has been accomplished by protecting the amino function as a phthalimido group with consequent stabilization of the oxocarbenium cation, and lowering the activation energy by introduction of trichloroacetimidate at the anomeric carbon.

(b) 6-Heteroaryl functions [6-(1,2,4-triazol-4-yl) and 6-(imidazol-1-yl)] were introduced into purine derivatives for regioselective N9 alkylation. The regiospecificity of alkylation mainly results from steric effects due to the coplanar conformation of the two linked …

Central Florida Future, Vol. 36 No. 62, May 19, 2004

Central Florida Future

Hitt scores $15,000; UCF faculty have been disappearing; Free yoga helps students to find themselves; Budget cuts for the arts leave groups struggling for money.

Individual Cell Growth Rates Of Marine Bacteria, Measured By Bromodeoxyuridine Incorporation, Koji Hamasaki, Richard A. Long, Farooq Azam

Faculty Publications

We tested the application of 5-bromo-2’-deoxyuridine (BrdU), a thymidine analogue that becomes incorporated into DNA during growth, to measure growth rates of individual marine bacteria cells. Immunocytochemical detection of BrdU incorporation into bacterial DNA has the potential for single-cell-based growth measurement. Optimized procedure for immunocytochemistry was applicable to 14 marine heterotrophic bacterial isolates belonging to g-proteobacteria, α-proteobacteria, Cytophaga-Flavobacterium-Bacteroides (CFB) group and Gram-positive bacteria. The relationship between cell-specific fluorescence intensity and specific growth rate was linearly correlated among CFB group isolates, which indicated a potential of the method for quantitative measurement. Analysis of the detection limit indicated …

Parks & Trails Partnership, Margaret N. Rees, Nancy Flagg, David Frommer

Presentations (PLI)

• UNLV is committed to demonstrating how the traditional values of higher education can be adapted to the conditions and needs of individuals and communities in the 21st century.
• Key macrothemes of the university’s strategic plan include Economic Development, Preservation of History & Culture, and Community Outreach & Collaboration.
• In keeping with these macrothemes, UNLV is embarking on several partnerships with the BLM and related agencies to provide a wide array of research, technical assistance, education, and service support on projects funded through the SNPLMA.
• UNLV is a research extensive university with academic departments and research centers and institutes that embrace …

The Importance Of A Critical Protonation State And The Fate Of The Catalytic Steps In Class A Β-Lactamases And Penicillin-Binding Proteins, Dasantila Golemi-Kotra, Samy O. Meroueh, Choonkeun Kim, Sergei B. Vakulenko, Alexey Bulychev, Ann J. Stemmler, Timothy L. Stemmler, Shahriar Mobashery

Biochemistry and Molecular Biology Faculty Publications

b-Lactamases and penicillin-binding proteins are bacterial enzymes involved in antibiotic resistance to b-lactam antibiotics and biosynthetic assembly of cell wall, respectively. Members of these large families of enzymes all experience acylation by their respective substrates at an active-site serine as the first step in their catalytic activities. A Ser-X-X-Lys sequence motif is seen in all these proteins and crystal structures demonstrate that the side chain functions of the serine and lysine are in contact with one another. Three independent methods were used in this report to address the question of the protonation state of this important lysine (Lys73) in the …

Cal Poly Electrical Engineering Student Takes First In State University Research Competition, Public Affairs Office

Press Releases

No abstract provided.

Uncoupling Conformational Change From Gtp Hydrolysis In A Heterotrimeric G Protein Alpha-Subunit, Celestine J. Thomas, Xinlin Du, Pilong Li, Ying Wang, Elliott M. Ross, Stephen R. Sprang

Biological Sciences Faculty Publications

Heterotrimeric G protein alpha (G alpha) subunits possess intrinsic GTPase activity that leads to functional deactivation with a rate constant of approximately 2 min(-1) at 30 degrees C. GTP hydrolysis causes conformational changes in three regions of G alpha, including Switch I and Switch II. Mutation of G202-->A in Switch II of G alpha(i1) accelerates the rates of both GTP hydrolysis and conformational change, which is measured by the loss of fluorescence from Trp-211 in Switch II. Mutation of K180-->P in Switch I increases the rate of conformational change but decreases the GTPase rate, which causes transient but …

Murray Ledger And Times, May 18, 2004, Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

E-News, Volume 2, No. 33, May 18, 2004, University Of South Florida St. Petersburg. Division Of University Relations

Points of Pride, Scene & Herd, and E-News

The May 18, 2004, issue of E-News, a newsletter for the University of South Florida St. Petersburg community.

Endogenous No Regulates Superoxide Production At Low Oxygen Concentrations By Modifying The Redox State Of Cytochrome C Oxidase, Miriam Palacios-Callender, Marisol Quintero, Veronica S. Hollis, Roger J. Springett, Salvador Moncada

Dartmouth Scholarship

We have investigated in whole cells whether, at low oxygen concentrations ([O(2)]), endogenous nitric oxide (NO) modulates the redox state of the mitochondrial electron transport chain (ETC), and whether such an action has any signaling consequences. Using a polarographic-and-spectroscopic-coupled system, we monitored redox changes in the ETC cytochromes b(H), cc(1), and aa(3) during cellular respiration. The rate of O(2) consumption (VO(2)) remained constant until [O(2)] fell below 15 microM, whereas the onset of reduction of cytochromes aa(3), part of the terminal ETC enzyme cytochrome c oxidase, occurred at approximately 50 microM O(2). Incubation of the cells with an inhibitor of …

Oliver Ranch Core Group Meeting: May 18, 2004, Red Rock Desert Learning Center

Reports (RRLC)

1. Where have we been and where are we going?
2. Line and Space Report
3. Committee Reports
4. Future Core Group Meetings