Digital Commons Network^™

Johne’S Disease, Inflammatory Bowel Disease, And Mycobacterium Paratuberculosis, Ofelia Barletta-Chacon, Luiz E. Bermudez, Raúl G. Barletta

School of Veterinary and Biomedical Sciences: Faculty Publications

Johne’s disease is a chronic diarrhea affecting all ruminants. Mycobacterium avium subsp. paratuberculosis (MAP), a slowly growing mycobacteria, is the etiologic agent. There is also a concern that MAP might be a causative agent of some cases of inflammatory bowel disease in humans, especially Crohn’s disease. Food products including pasteurized bovine milk have been suggested as potential sources of human infection. This review addresses microbial factors that may contribute to its pathogenicity. In addition, the experimental evidence defining MAP as the cause of Johne’s disease and the issues and controversies surrounding its potential pathogenic role in humans are discussed.

Observations On Myiasis By The Calliphorids, Bufolucilia Silvarum And Bufolucilia Elongata, In Wood Frogs, Rana Sylvatica, From Southeastern Wisconsin, Matthew G. Bolek, John J. Janovy Jr.

John J. Janovy, Jr. Publications

Larvae of certain species of blowflies (Calliphoridae) can cause myiasis in frogs and toads, but there are few reports from North American amphibians. Of these, most are from toads (bufonids). In this study, we observe primary myiasis in a population of juvenile wood frogs, Rana sylvatica, collected on August 22-23, 2003, from southeastern Wisconsin and compare our observations with previous studies on myiasis from toads. Two (5%) of 39 frogs were infected by the blow fly Bufolucilia silvarum, with an intensity of 28 and 31, whereas 1 (2.5%) of 39 frogs was infected by the blow fly Bufolucilia …

Isolation Versus Quarantine And Alternative Measures To Control Emerging Infectious Diseases, Fahad A. Al-Ateeg

Saudi Medical Journal

In the past 25 years, the world has witnessed the emergence and re-emergence of many infectious diseases. In the early stages of their emergence, isolation and quarantine may be the only and last resort to effectively control infectious diseases when we are confronted with limited or no knowledge of a newly identified and previously unknown contagious disease, which causes a serious public health threat either locally or internationally. The article traces back the origins of isolation and quarantine; defines precisely the terms isolation and quarantine as they are currently used in the modern era; compare and contrast these terms; identifies …

Effectiveness Of Hepatitis B Vaccination In Children Of Chronic Hepatitis B Mothers, Peyman Adibi, Rezvan Ghassemian, Seyed-Moayed Alavian, Mitra Ranjbar, Amir H. Mohammadalizadeh, Fariborz Nematizadeh, Mojgan Mamani, Mahdi Rezazadeh, Fariba Keramat, Ali Ardalan, Abbas Esmaeili, Mohammad R. Zali

Saudi Medical Journal

OBJECTIVE: Although all newborns in Iran have been vaccinated against hepatitis B since March 1993, routine screening of pregnant women has not been conducted in prenatal care programs, yet transmission of hepatitis B via the maternal-fetal route is still a viable likelihood, which must be entertained. METHODS: The subjects were divided into 2 groups. The exposed group comprised 97 vaccinated children whose mothers were seropositive for hepatitis B surface antigen (HBsAg) and had not received hepatitis immunoglobulin at birth. The unexposed group consisted of 87 vaccinated children whose mothers were seronegative for hepatitis B surface antigen. We compared these 2 …

Salmonellosis And Ulcerative Colitis. A Causal Relationship Or Just A Coincidence, Ali O. Karaoglu, Vahit Yukselen, Gunay T. Ertem, Muhan Erkus

Saudi Medical Journal

Coincidence of salmonellosis and ulcerative colitis is a rare clinical problem. Salmonella infection was reported to complicate the ulcerative colitis, as either facilitating its occurrence or activation. In this article, we present a case with salmonellosis whose clinicopathological findings also suggested ulcerative colitis. The patient improved rapidly after taking additional mesalazine to norfloxacin treatment. We conclude that salmonella infection might have either been coincidentally present or might have triggered an early ulcerative colitis in this patient who did not have history of inflammatory bowel diseases. In case of persistent severe diarrhea despite appropriate treatment, the possibility of a coincident inflammatory …

New Species Of Cinclotaenia Macy, 1973 (Cyclophyllidea: Dilepididae) From Cinclus Leucocephalus Tschudi (Passeriformes: Cinclidae) In Bolivia, Boyko B. Georgiev, Scott Lyell Gardner

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Two new species of Cinclotaenia (Cyclophyllidea: Dilepididae) are described from the small intestine of Cinclus leucocephalus (Aves: Passeriformes: Cinclidae) collected in the Yungas region of Bolivia. Cinclotaenia minuta n. sp. is characterized by possessing a minute strobila with a maximum body length of 1.58 mm, consisting of 5–10 proglottids, 19–22 rostellar hooks with lengths from 16 to 17 mm, 12–17 testes per proglottid, and eggs forming packets without filaments. Cinclotaenia boliviensis n. sp. has bandlike strobila with a length up to 26 mm with 67–74 proglittids, 22 rostellar hooks with length 39–42 mm, 43–68 testes, and eggs forming packets possessing …

Two Species Of Synhimantus (Dispharynx) Railliet, Henry And Sisoff, 1912 (Nematoda: Acuarioidea: Acuariidae), In Passerine Birds From The Área De Conservación Guanacaste, Costa Rica, Luping Zhang, Daniel R. Brooks, Douglas Causey

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Members of 2 species of Synhimantus (Dispharynx) live under the lining of the gizzard in passerine birds from the Área de Conservación Guanacaste, Costa Rica. Synhimantus (Dispharynx) nasuta (Rudolphi, 1819) occurs in Thraupis episcopus, Turdus grayi, Caryothraustes poliogaster, Platyrinchus cancrominus, Ramphocaenus melanurus, Vermivora peregrina, and Geothlypis poliocephala. A single male, in Turdus grayi, apparently representing a new species, distinguishable from all other species of Synhimantus (Dispharynx) by having similar shaped left and right spicules, is described but not named.

Phylogeny For Species Of Haemonchus (Nematoda: Trichostrongyloidea): Considerations Of Their Evolutionary History And Global Biogeography Among Camelidae And Pecora (Artiodactyla), Eric P. Hoberg, J. Ralph Lichtenfels, Lynda M. Gibbons

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Phylogenetic analysis of 25 morphological characters among the 12 species of Haemonchus resulted in one most parsimonious tree (60 steps; consistency index 5 0.67, retention index 5 0.80). Monophyly for Haemonchus was diagnosed by three unequivocal synapomorphies, including the asymmetric origin of the dorsal ray, relative size of the ventral rays, and the presence of a barb on each spicule tip. Species of Haemonchus have complex histories with respect to host and geographic associations: (1) origins in Africa with basal diversification in antelopes (H. krugeri, H. lawrencei, H. dinniki, H. horaki), (2) independent events of …

Descriptive And Comparative Study Of The Nutritional Knowledge And Behavior Of Mothers Of Young Children Who Have Received Targeted Nutritional Education And Those Who Have Not As A Method To Ascertain The Effectiveness Of The Little Tree Nutritional And Educational Centre In Combating Malnutrition In The Pienaarsig Township Of Nieu Bethesda, Eastern Cape Province, South Africa, Amelia Peterson

Independent Study Project (ISP) Collection

No abstract provided.

Learning Opportunities 2004/2005, Illinois Mathematics And Science Academy

Course Catalogs

Students must enroll in a core mathematics course each semester, advancing to the highest level possible during their six semesters at IMSA. Numerous elective options are available for expanded exploration.

A Vibrio Cholerae Classical Tcpa Amino Acid Sequence Induces Protective Antibody That Binds An Area Hypothesized To Be Important For Toxin-Coregulated Pilus Structure, Ronald K. Taylor, Thomas J. Kirn, Michael D. Meeks, Terri K. Wade, William F. Wade

Dartmouth Scholarship

Vibrio cholerae is a gram-negative bacterium that has been associated with cholera pandemics since the early 1800s. Whole-cell, killed, and live-attenuated oral cholera vaccines are in use. We and others have focused on the development of a subunit cholera vaccine that features standardized epitopes from various V. cholerae macromolecules that are known to induce protective antibody responses. TcpA protein is assembled into toxin-coregulated pilus (TCP), a type IVb pilus required for V. cholerae colonization, and thus is a strong candidate for a cholera subunit vaccine. Polypeptides (24 to 26 amino acids) in TcpA that can induce protective antibody responses have …

T-Cell Responses To The M3 Immune Evasion Protein Of Murid Gammaherpesvirus 68 Are Partially Protective And Induced With Lytic Antigen Kinetics, Joshua J. Obar, Douglas C. Donovan, Sarah G. Crist, Ondine Silvia, James P. Stewart, Edward J. Usherwood

Dartmouth Scholarship

DNA vaccination with the M3 gene, encoding an immune evasion molecule expressed during both the acute lytic and persistent phases of murid gammaherpesvirus 68 infection, yielded a significantly lower titer of virus in the lung than controls. The protection seen was dependent on T cells, and we mapped an epitope recognized by CD8 T cells. The immune response to this epitope follows the same kinetics as lytic cycle antigens, despite the fact that this gene is expressed in both lytic and persistent stages of infection. This has important implications for our understanding of T-cell responses to putative latency-associated gammaherpesvirus proteins …

Healthy Living In The Pacific Islands: Results Of A Focus Group Process To Identify Perceptions Of Health And Collaboration In The U.S-Affiliated Pacific Islands, Nicky Davison, Randall Workman, Yihe Goh Daida, Rachel Novotny

Journal of Extension

A focus group process was used to gather data on perceptions of health and community collaboration within 6 U.S. affiliated Pacific Islands as part of a process to encourage a community-based participatory approach to addressing community health issues and planning. The focus groups revealed Pacific Islanders' perceptions of health and key local health issues and elements of collaboration. The results were applied to a community-oriented planning process, resulting in the creation of a broad planning framework within which islands could implement their own activities. This approach shows potential for initiating future activities in which communities collaborate in the planning process.

Patterns Of Tuberculosis In The Central Nervous System, Soobia Raza, Aliyah Sadaf, Faisal Fecto, Rushna Pervez Ali, Muhammad Ehsan Bari, Ather Enam

Medical College Documents

Tuberculous involvement of central nervous system (CNS), although not very frequent, results in severe morbidity. Tuberculosis (TB) is endemic in developing countries but even in developed countries, after an initial decline up until 1980’s, incidence of TB is on the rise. The AIDS epidemic, emergence of multi-drug resistant strains and immigration of people from endemic areas are some of the factors significantly contributing to this increase. Consequently, the burden of central nervous system tuberculosis has increased significantly worldwide.

Job Security And Bargaining Rights Of Federal Government Employees, Mark D. Roth, Gony Frieder, Anne Wagner

University of the District of Columbia Law Review

From the beginning of his administration, President George Walker Bush undertook to curtail employment rights, particularly those previously enjoyed by federal government workers. In the wake of the September 11th attacks, however, the Bush Administration was able to launch a full-scale attack on federal employment rights under the guise of national security. While the expansion of government power in the name of national security has come under substantial media and political scrutiny, much of this attention has focused on the threat posed to individual rights. Increased federal power under the USA PATRIOT Act' and other measures2 ostensibly intended to enhance …

History-Adjusted Marginal Structural Models And Statically-Optimal Dynamic Treatment Regimes, Mark J. Van Der Laan, Maya L. Petersen

U.C. Berkeley Division of Biostatistics Working Paper Series

Marginal structural models (MSM) provide a powerful tool for estimating the causal effect of a treatment. These models, introduced by Robins, model the marginal distributions of treatment-specific counterfactual outcomes, possibly conditional on a subset of the baseline covariates. Marginal structural models are particularly useful in the context of longitudinal data structures, in which each subject's treatment and covariate history are measured over time, and an outcome is recorded at a final time point. However, the utility of these models for some applications has been limited by their inability to incorporate modification of the causal effect of treatment by time-varying covariates. …

Il-2 Receptor Signaling Regulates Ets1 Translation In Human Natural Killer Cells, Eric M. Grund

MUSC Theses and Dissertations

Natural Killer (NK) cells are critical for protection from cancer and infectious disease. The hypothesis that there is a molecular link between IL-2 receptor signaling and Ets1 was investigated. This hypothesis was based on the correlation between an NK-deficient phenotype generated by gene targeting of the Ets1 transcription factor, IL-2 receptor, IL-2 and IL-15, indicating that each of these proteins is required for the proper development and function of NK cells. The findings presented show that both IL-2 and IL-15 induce a post-transcriptional regulation of Ets1 in NK cells. Pharmacological and transient transfection analyses, using a method developed within to …

E-News, Volume 2, No. 52, September 24, 2004, University Of South Florida St. Petersburg. Division Of University Relations

Points of Pride, Scene & Herd, and E-News

The September 24, 2004, issue of E-News, a newsletter for the University of South Florida St. Petersburg community.

Washington University Record, September 24, 2004

Washington University Record

No abstract provided.

Waccnes Containing Bovine Herpe Svirus 1 Attenuated By Mutation In Latency-Related Gene, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Vaccines for pathogenic Strains of bovine herpesvirus 1 (BHV-1) which are based on attenuated BHV-1 having a mutation in the latency-related gene are provided. Live, attenuated vaccines are also provided which express anti gens from other viral or bacterial pathogens and thus form the basis of a variety of vaccines.

A Hypothesis Test For The End Of A Common Source Outbreak, Ron Brookmeyer, Xiaojun You

Johns Hopkins University, Dept. of Biostatistics Working Papers

The objective of this paper is to develop a hypothesis testing procedure to determine whether a common source outbreak has ended. We do not assume that the calendar date of exposure to the pathogen is known. We assume an underlying parametric model for the incubation period distribution of a 2-paramter exponential model with a guarantee time, although the parameters are not assumed to be known. The hypothesis testing procedure is based on the spacings between ordered calendar dates of disease onset of the cases. A simulation study was performed to evaluate the robustness of the methods to a lognormal model …

September 13, 2004 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Spectrophotometric System And Method For The Identification And Characterization Of A Particle In A Bodily Fluid, Luis Humberto Garcia-Rubio, Yvette D. Mattley, German Leparc, Manuel Bayona, Andres Cardenas

USF Patents

An infectious disease or disorder in a fluid, such as a mammalian blood sample, is detected by taking a transmission spectrum of a test sample in at least a portion of the ultraviolet visible near-infrared and comparing the spectrum with a standard sample spectrum. From the comparison it is then determined whether the fluid from the test sample contains an infectious disease or disorder, and an identity of the infectious disease or disorder is determined. Spectroscopic and multiwavelength turbidimetry techniques provide a rapid, inexpensive, and convenient means for diagnosis. The comparison and determination steps may be performed visually or by …

Washington University Record, September 3, 2004

Washington University Record

No abstract provided.

On Time Series Analysis Of Public Health And Biomedical Data, Scott L. Zeger, Rafael A. Irizarry, Roger D. Peng

Johns Hopkins University, Dept. of Biostatistics Working Papers

A time series is a sequence of observations made over time. Examples in public health include daily ozone concentrations, weekly admissions to an emergency department or annual expenditures on health care in the United States. Time series models are used to describe the dependence of the response at each time on predictor variables including covariates and possibly previous values in the series. Time series methods are necessary to account for the correlation among repeated responses over time. This paper gives an overview of time series ideas and methods used in public health research.

Law & Health Care Newsletter, V. 12, No. 1, Fall 2004

Law & Health Care Newsletter

No abstract provided.

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

Idcr: Infectious Diseases In Corrections Report, Vol. 7 No. 9, Infectious Diseases In Corrections

Infectious Diseases in Corrections Report (IDCR)

No abstract provided.

Revisiting Vaccine Hesitancy, Barriers And Motivators To Obtaining A Flu Vaccine In A New Covid-19 Pandemic World, Ann M. Mayo Rn, Dnsc, Faan, Steffanie R. Cobler Np

School of Nursing and Health Science: Faculty Scholarship

Purpose

To describe and compare patient perceived barriers and motivators and decision-making conflict between two groups of hospitalized patients, those who receive flu vaccines and those who do not.

Data Sources

Data collection during 2003 included extracting data from databases and mailing two surveys to 436 discharged patients. One hundred eight (108) patients participated in the study.

Conclusions

Top barriers included fear of side effects from vaccine (35%) and fear of contracting the flu (30%). Top motivators for obtaining a flu vaccine included previous vaccination (93%) and provider recommendation (62%). Barriers, motivators and patient decisional conflict differed depending upon patient …

Involvement Of Raft-Like Plasma Membrane Domains Of Entamoeba Histolytica In Pinocytosis And Adhesion, Richard C. Laughlin, Glen C. Mcgugan, Rhonda R. Powell, Brenda H. Welter, Lesly A. Temesvari

Publications

Lipid rafts are highly ordered, cholesterol-rich, and detergent-resistant microdomains found in the plasma membrane of many eukaryotic cells. These domains play important roles in endocytosis, secretion, and adhesion in a variety of cell types. The parasitic protozoan Entamoeba histolytica, the causative agent of amoebic dysentery, was determined to have raft-like plasma membrane domains by use of fluorescent lipid analogs that specifically partition into raft and nonraft regions of the membrane. Disruption of raft-like membrane domains in Entamoeba with the cholesterol-binding agents filipin and methyl-β-cyclodextrin resulted in the inhibition of several important virulence functions, fluid-phase pinocytosis, and adhesion to host …