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2003

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Relationships Of Chute-Side Measurements To Carcass Measurements, James C. Macdonald, Terry J. Klopfenstein, Galen E. Erickson, Casey Macken, Jeffrey Folmer Jan 2003

Relationships Of Chute-Side Measurements To Carcass Measurements, James C. Macdonald, Terry J. Klopfenstein, Galen E. Erickson, Casey Macken, Jeffrey Folmer

Nebraska Beef Cattle Reports

Three data sets were compiled to determine the relationship of weight, performance, hip height and ultrasound-measured fat thickness to hot carcass weight and fat thickness. Weight is generally the best predictor of relative differences in carcass weight at any time in the production system. Hip heights do not predict relative differences in carcass weight. Although the combination of hip height and weight is a more precise indicator of carcass weight than is hip height alone, generally this combination is inferior to weight alone. Only ultrasound-measured fat thickness predicted relative differences in fat thickness. Prediction of relative differences in carcass weight …

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Rck Domain Model Of Calcium Activation In Bk Channels, Alexander R. Pico Jan 2003

Rck Domain Model Of Calcium Activation In Bk Channels, Alexander R. Pico

Student Theses and Dissertations

Potassium ion channels are ubiquitously expressed from bacteria to mammals where they are involved in various processes ranging from the regulation of osmotic pressure in a single cell to the electrical response in muscle fibers to the generation of action potentials in neurons. The BK channel family (BK for Big K+ conductance) is an interesting subfamily of K+ channels responsive to both membrane voltage and intracellular calcium ion. The unique, high-affinity Ca2+ sensitivity of BK channels is critical to their physiological function in various cell types. The mechanism by which Ca2+ activates BK channel gating, however, …

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Protein Semi-Synthesis In Vivo, Izabela Giriat Stankiewicz Jan 2003

Protein Semi-Synthesis In Vivo, Izabela Giriat Stankiewicz

Student Theses and Dissertations

Incorporation of chemical probes into proteins is a powerful way to elucidate biological processes and to engineer novel function. This thesis describes the ligation of synthetic molecules to target proteins in an intracellular environment, and the use of semi-synthetic proteins for whole animal studies. In the first approach a cellular protein is genetically tagged with one half of a split-intein. The complementary half is linked in vitro to the synthetic probe and this fusion is delivered into cells using a transduction peptide. Association of the intein halves in the cytosol triggers protein transsplicing, resulting in the ligation of the probe …

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Global Citizenship, Gil Carlos Rodriguez Iglesias Jan 2003

Global Citizenship, Gil Carlos Rodriguez Iglesias

Journal of Diplomacy and International Relations

No abstract provided.

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Death By Any Other Name: The Federal Government's Inconsistent Treatment Of Drugs Used In Lethal Injections And Physician-Assisted Suicide, Colin Miller Jan 2003

Death By Any Other Name: The Federal Government's Inconsistent Treatment Of Drugs Used In Lethal Injections And Physician-Assisted Suicide, Colin Miller

Journal of Law and Health

While the FDA is under no legal obligation to regulate the drugs used in executions, these recent developments certainly create a moral imperative requiring review. This paper will argue that the federal government cannot consistently refrain from regulating lethal injection drugs while arguing for prosecution of those prescribing drugs to be used by patients in assisted suicide. Part II will look at the opinions in Chaney and the factors behind the FDA's decision not to regulate the drugs used in executions. Part III will look at Oregon's Death with Dignity Act and its authorization by the Supreme Court. Parts IV-VI …

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Advanced Display Technologies: An Investigation Of The Emerging And Developing Technologies Related To The Generation Beyond Print-On-Paper, Michael Kleper Jan 2003

Advanced Display Technologies: An Investigation Of The Emerging And Developing Technologies Related To The Generation Beyond Print-On-Paper, Michael Kleper

Books

The purpose of this paper is to present information about new display technologies that are competing with print. Display technology continues to mature, as in the case of full-color OLED, which has been incorporated into its first consumer product, The Kodak EasyShare LS 633 digital camera. Digital ink pioneer E Ink, through its partnership with Philips Electronics, will introduce its first commercial product in early 2004. Gyricon Media, the inventor of the electronic paper category, has opened its first manufacturing plant. In addition, new flexible display technologies have been introduced, such as SiPix Microcup, and the electronic display form-factor has …

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A Case-Based Reasoning System For Classifying Malay Traditional Herbs / Ismaily Johari, Johari Ismaily Jan 2003

A Case-Based Reasoning System For Classifying Malay Traditional Herbs / Ismaily Johari, Johari Ismaily

Student Works (2000-2009)

The purpose of this project is to develop a system using case-based reasoning to classify the various types of Malay Traditional herbs. The task of classifying Malay Traditional herbs had always been done by botanist. Malay Traditional herbs practitioner, herbalists and people interested on the herbs. The classification were usually done by identifying the physical attributes of the herbs, based on the features of its leaf, root, flower, fruit and stem. Each of them owns its own unique physical features making the process of classifying essential to determine the type of the herbs. This project focuses on the methods of …

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Anatomi Tubuh Manusia Berasaskan Web / Ahmed Izal Hamdy, Hamdy Ahmed Izal Jan 2003

Anatomi Tubuh Manusia Berasaskan Web / Ahmed Izal Hamdy, Hamdy Ahmed Izal

Student Works (2000-2009)

Laporan ini adalah berkenaan dengan pembangunan laman web sistem anatomi tubuh manusia. Sesuatu sistem baru yang hendak dibangunkan perlulah melalui peringkat-peringkat seperti penyelidikan dan pembangunan. Sebelum dan setelah sistem ini sempurna dibangunkan, ianya telah melalui beberapa peringkat penyelidikan dan pembangunan, dan ini dapat ditunjukan atau diterangkan dengan lebih jelas dengan membahagikan penerangan-penerangan yang berkaitan kepada beberapa bahagian iaitu Pengenalan, Kajian Literasi, Metodologi, Analisis Sistem, Rekabentuk Sistem, Perlaksanaan, Pengujian, Penyelengaraan dan akhir sekali Penilaian. Laman web anatomi tubuh manusia telah dibangunkan dengan tujuan untuk memberikan banyak kebaikkan kepada para pengguna sasaran. Antara kelebihannya ialah ianya laman web berlatarbelakangkan anatomi tubuh manusia …

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Collaborative Learning In 3d Environment / Nurul Marliana Badruldin, Badruldin Nurul Marliana Jan 2003

Collaborative Learning In 3d Environment / Nurul Marliana Badruldin, Badruldin Nurul Marliana

Student Works (2000-2009)

"Collaborative Learning In 3D Environment" merupakan satu sistem yang membantu pembelajaran yang dijalankan secara berkumpulan melalui persembahan persekitaran grafik dalam bentuk 3 dimensi yang akan digunakan berasaskan web. Sistem ini akan membantu suasana pembelajaran di dalam kelas supaya lebih aktif dan menyeronokkan kerana ia boleh dijadikan sebagai salah satu alat bantuan mengajar. "Exploring Virtual World Of Photosynthesis" adalah nama bagi sistem ini. Sistem ini mengandungi beberapa bahagian atau subtopik-subtopik tertentu dalam menerangkan petjalanan prpses fotosintesis. Oleh itu, sistem ini amat sesuai digunakan dalam mata pelajaran biologi. Samada bagi peringkat sekolah menengah tinggi, prauniversiti atau ijaza.h satjana muda. Sistem ini akan …

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Counselling Portal: Askakak.Com / Khairiah Rahmat, Rahmat Khairiah Jan 2003

Counselling Portal: Askakak.Com / Khairiah Rahmat, Rahmat Khairiah

Student Works (2000-2009)

We have reached the beginning of a new millennium, and needless to say, information technology is relatively changing very rapidly Along with this revolution, the lives of people have become more complex and convoluted, with problems and insecurities creeping up endlessly.Traditional face-to-face counselling does not prove to be the best remedy for this phenomenon anymore. Living at a fast pace has forced people to turn technology to provide them with the best solution for solving their problems and soothing their troubled mind-online counselling. Online counselling has brought us into a new world of communication and problem solving. Ironically computer counselling …

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Navigating Unchartered Waters: Intellectual Property Rights Surrounding Genomics Research & Development Information, Lawrence M. Sung Jan 2003

Navigating Unchartered Waters: Intellectual Property Rights Surrounding Genomics Research & Development Information, Lawrence M. Sung

Journal of Health Care Law and Policy

No abstract provided.

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Piercing The Academic Veil: Disaffecting The Common Law Exception To The Patent Infringement Liability And The Future Of A Bona Fide Research Use Exemption After Madey V. Duke University, Lawrence M. Sung, Claire M. Maisano Jan 2003

Piercing The Academic Veil: Disaffecting The Common Law Exception To The Patent Infringement Liability And The Future Of A Bona Fide Research Use Exemption After Madey V. Duke University, Lawrence M. Sung, Claire M. Maisano

Journal of Health Care Law and Policy

No abstract provided.

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Biotechnology And Human Dignity, A Necessary And Compatible Union, Ellen Judge Hayes Jan 2003

Biotechnology And Human Dignity, A Necessary And Compatible Union, Ellen Judge Hayes

Journal of Health Care Law and Policy

No abstract provided.

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Lawyers' Poker, Steven Lubet Jan 2003

Lawyers' Poker, Steven Lubet

University of Miami Law Review

No abstract provided.

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Annual Report For The Town Of New Castle Fiscal Year 2002-2003., New Castle Town Representatives Jan 2003

Annual Report For The Town Of New Castle Fiscal Year 2002-2003., New Castle Town Representatives

New Castle, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

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Size Selective Recognition Of Sirna By An Rna Silencing Suppressor, Jeff Vargason, Gyorgy Szittya, Jozsef Burgyan, Traci M. Tanaka Hall Jan 2003

Size Selective Recognition Of Sirna By An Rna Silencing Suppressor, Jeff Vargason, Gyorgy Szittya, Jozsef Burgyan, Traci M. Tanaka Hall

Faculty Publications - Department of Biological & Molecular Science

RNA silencing in plants likely exists as a defense mechanism against molecular parasites such as RNA viruses, retrotransposons, and transgenes. As a result, many plant viruses have adapted mechanisms to evade and suppress gene silencing. Tombusviruses express a 19 kDa protein (p19), which has been shown to suppress RNA silencing in vivo and bind silencing-generated and synthetic small interferingRNAs (siRNAs) in vitro. Here we report the 2.5 A° crystal structure of p19 from the Carnation Italian ringspot virus (CIRV) bound to a 21 nt siRNA and demonstrate in biochemical and in vivo assays that CIRV p19 protein acts as molecular …

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Are Hummingbirds Facultatively Ammonotelic? Nitrogen Excretion And Requirements As A Function Of Body Size, Todd J. Mcwhorter, Donald R. Powers, Carlos Martinez Del Rio Jan 2003

Are Hummingbirds Facultatively Ammonotelic? Nitrogen Excretion And Requirements As A Function Of Body Size, Todd J. Mcwhorter, Donald R. Powers, Carlos Martinez Del Rio

Faculty Publications - Department of Biological & Molecular Science

Most birds are uricotelic. An exception to this rule may be nectar-feeding birds, which excrete significant amounts of ammonia under certain conditions. Although ammonia is toxic, because it is highly water soluble its excretion may be facilitated in animals that ingest and excrete large amounts of water. Birdpollinated plants secrete carbohydrate- and water-rich floral nectars that contain exceedingly little protein. Thus, nectarfeeding birds are faced with the dual challenge of meeting nitrogen requirements while disposing of large amounts of water. The peculiar diet of nectar-feeding birds suggests two hypotheses: (1) these birds must have low protein requirements, and (2) when …

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Hypothalamic Proopiomelanocortin Neurons Are Glucose Responsive And Express Katp Channels, Nurhadi Ibrahim, Martha A. Bosch, James L. Smart, Jian Qiu, Marcelo Rubinstein, Oline K. Rønnekleiv, Malcolm J. Low, Martin J. Kelly Jan 2003

Hypothalamic Proopiomelanocortin Neurons Are Glucose Responsive And Express Katp Channels, Nurhadi Ibrahim, Martha A. Bosch, James L. Smart, Jian Qiu, Marcelo Rubinstein, Oline K. Rønnekleiv, Malcolm J. Low, Martin J. Kelly

Faculty Publications - Department of Biological & Molecular Science

Hypothalamic proopiomelanocortin (POMC) neurons are critical for controlling homeostatic functions in the mammal. We used a transgenic mouse model in which the POMC neurons were labeled with enhanced green fluorescent protein to perform visualized, whole-cell patch recordings from prepubertal female hypothalamic slices. The mouse POMC-enhanced green fluorescent protein neurons expressed the same endogenous conductances (a transient outward K current and a hyperpolarization-activated, cation current) that have been described for guinea pig POMC neurons. In addition, the selective -opioid receptor agonist DAMGO induced an outward current (maximum of 12.8 1.2 pA), which reversed at K equilibrium potential (EK), in the majority …

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The Anorexigenic Fatty Acid Synthase Inhibitor, C75, Is A Nonspecific Neuronal Activator, Kanji A. Takahashi, James L. Smart, Hongyan Liu, Roger D. Cone Jan 2003

The Anorexigenic Fatty Acid Synthase Inhibitor, C75, Is A Nonspecific Neuronal Activator, Kanji A. Takahashi, James L. Smart, Hongyan Liu, Roger D. Cone

Faculty Publications - Department of Biological & Molecular Science

C75, a recently derived compound that potently suppresses feeding and induces weight loss, has been proposed to act mainly by inhibiting fatty acid synthase (FAS) in central neurons that control feeding. For example, normal, fasting- associated, hypothalamic increases in neuropeptide Y (NPY)/Agouti-related protein (AGRP) expression and decreases in proopiomelanocortin (POMC)/cocaine and amphetamine regulated transcript (CART) expression were reported to be blocked by C75. Using loose-patch extracellular recording in acute slices, we tested the effect of C75 on anorexigenic POMC neurons and orexigenic NPY neurons of the hypothalamic arcuate nucleus, which were identified by promoter-driven GFP expression, as well as on …

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Intracellular Dynamics Of Lead And Calcium In Lead-Exposed Cultured Neurons Of Aplysia Californica (Mollusca: Opisthobranchia), Catherine T. Tamse Jan 2003

Intracellular Dynamics Of Lead And Calcium In Lead-Exposed Cultured Neurons Of Aplysia Californica (Mollusca: Opisthobranchia), Catherine T. Tamse

Open Access Dissertations

The neurotoxin lead (Pb2+) is a continuing health and environmental problem. However, its neurotoxic mechanism remains unclear. Since calcium (Ca2+) is vital in cellular processes and with Pb2+ reported to interfere with Ca2+-mediated processes, the hypothesis that Pb2+ subverts Ca2+ homeostasis by entering cells through Ca2+ transport pathways and displacing intracellular Ca2+ ([Ca2+] i) was investigated. A multi-technique approach tested this hypothesis. Using cultured Aplysia bag cell neurons, changes in transmembrane Ca2+ flux after Pb2+ exposure were directly measured with the Ca2+-selective self-referencing electrode. Cumulative concentrations of extracellular Pb2+ produced a corresponding and significant (P < 0.05) increase in Ca 2+ efflux, independent of time exposure. Ca2+ channel blockers Co2+, La3+, and verapamil inhibited Pb2+-induced flux. The sarco/endoplasmic reticulum Ca 2+-ATPase pump inhibitors, thapsigargin and cyclopiazonic acid, both elicited a Ca2+ efflux reflecting inhibition of ER pumps and [Ca2+]i release. Furthermore, Pb2+ evoked a moderate and sustained elevation in thapsigargin-stimulated Ca 2+ efflux. For morphological evidence that Pb2+ can mobilize [Ca 2+]i, potassium pyroantimonate (KPA) cytochemistry of bag cells were analyzed. 2% KPA resulted in widespread electron-dense precipitates. 10 mM EGTA + KPA or 200 μM Pb2+ + KPA both produced marked reductions of precipitates in neurons. X-ray microanalysis confirmed antimony (Sb) in precipitates but could not separate the overlapping Ca2+-Sb spectral peaks. However, reduced precipitates in EGTA-incubated cells indicate presence of Ca2+ in intracellular precipitates observed. No apparent pathological changes were correlated to Pb2+ exposure. The effects of Pb2+ on [Ca2+]i using the fluorescent Ca2+ indicator, chlortetracycline (CTC), was examined. Control neurons incubated in 10 μM CTC demonstrated extensive yellow-green fluorescence while reduced fluorescence intensities were seen in cells exposed to 200 μM Pb2+. Multi-sized punctate fluorescence were observed along the perimeter and sometimes, throughout the soma. No neuronal autofluorescence nor neuritic fluorescence in control and Pb2+-exposed cells were detected. Average fluorescence intensities between control and Pb2+-exposed neurons were statistically significant (P < 0.0005). Collectively, these results are consistent with the hypothesis that Pb 2+ perturbs Ca2+ homeostasis via mobilization of [Ca 2+]i. Pb2+ operates through Ca2+ transport pathways as shown by changes in transmembrane Ca 2+ flux, in KPA precipitate reactions, and in CTC fluorescence.

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On Democracy As A Shar'i Moral Presumption: Response To Khaled Abou El Fadl, Anver M. Emon Jan 2003

On Democracy As A Shar'i Moral Presumption: Response To Khaled Abou El Fadl, Anver M. Emon

Fordham International Law Journal

Khaled Abou El Fadl has done more in his Article than simply argue the possibility of democracy in the Muslim world. He reminds us that Islam is not a monolithic idea lacking varying contours, possibilities, and dispositions. Whether in talking about an Islamic legal system or an Islamic political system, the most frequent mistake is assuming that there is an ideal vision of such systems that precludes debate, difference, and the continued search for possibilities. Another common mistake is to presume that the limits of an “Islamic political system” are inherent in the existing practice of so-called Muslim States. To …

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Why Does The American Constitution Lack Social And Economic Guarantees?, Cass R. Sunstein Jan 2003

Why Does The American Constitution Lack Social And Economic Guarantees?, Cass R. Sunstein

Public Law and Legal Theory Working Papers

Why does the American Constitution lack contain social and economic guarantees, which appear in most contemporary constitutions? This essay explores four possible answers: chronological, cultural, institutional, and realist. The chronological explanation emphasizes the fact that in the late eighteenth century, social and economic rights simply were not on the viewscreen for constitution-makers. The point is correct, but as a complete account, the chronological explanation fails for the simple reason that constitutional meaning changes over time. The institutional explanation emphasizes that Americans typically see constitutional rights not as mere goals or aspirations, but as pragmatic instruments for judicial enforcement. The difficulty …

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Land Preservation, John R. Nolon Jan 2003

Land Preservation, John R. Nolon

Elisabeth Haub School of Law Faculty Publications

This exploration of local preservation law and practice recognizes the critical influences of federal, state, and regional governments. Local governments are instruments of state governments; municipalities derive their authority from state statutes. Extensive control over land use has been given to localities, but important powers have been retained. State governments are the partners of federal agencies that are charged with protecting environmental resources that are subject to federal jurisdiction. The land use system that has evolved over the last century in this country is intensely intergovernmental and interdependent. While this system was not designed as a whole and is often …

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An Upper Basin Perspective On California's Claims To Water From The Colorado River Part Ii: The Development, Implementation And Collapse Of California's Plan To Live Within Its Basic Apportionment, James S. Lochhead Jan 2003

An Upper Basin Perspective On California's Claims To Water From The Colorado River Part Ii: The Development, Implementation And Collapse Of California's Plan To Live Within Its Basic Apportionment, James S. Lochhead

Water Law Review

No abstract provided.

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The Blind Man And The Elephant: Describing Drought In Colorado, Sarah Klahn Jan 2003

The Blind Man And The Elephant: Describing Drought In Colorado, Sarah Klahn

Water Law Review

No abstract provided.

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Neuse River Found., Inc. V. Smithfield Foods, Inc., 574 S.E.2d 48, Regan Rozier Jan 2003

Neuse River Found., Inc. V. Smithfield Foods, Inc., 574 S.E.2d 48, Regan Rozier

Water Law Review

No abstract provided.

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N.C. Home Builders Ass'n V. Envtl. Mgmt. Comm'n, 573 S.E.2d 732 (N.C. Ct. App. 2002), David Hall Jan 2003

N.C. Home Builders Ass'n V. Envtl. Mgmt. Comm'n, 573 S.E.2d 732 (N.C. Ct. App. 2002), David Hall

Water Law Review

No abstract provided.

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The Twenty-First Annual Water Law Conference Into The Twenty-First Century: Water Rights, Water Supply, Water Quality, Holly Kirsner Jan 2003

The Twenty-First Annual Water Law Conference Into The Twenty-First Century: Water Rights, Water Supply, Water Quality, Holly Kirsner

Water Law Review

No abstract provided.

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Robert Glennon, Water Follies: Groundwater Pumping And The Fate Of America's Fresh Waters, Gloria Maria Soto Jan 2003

Robert Glennon, Water Follies: Groundwater Pumping And The Fate Of America's Fresh Waters, Gloria Maria Soto

Water Law Review

No abstract provided.

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Geoffrey O'Gara, What You See In Clear Water: Indians, Whites, And A Battle Over Water In The American West, Owen Walker Jan 2003

Geoffrey O'Gara, What You See In Clear Water: Indians, Whites, And A Battle Over Water In The American West, Owen Walker

Water Law Review

No abstract provided.

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