Digital Commons Network^™

Analysis Of Protein Sequences Using Time Frequency And Kolmogorov-Smirnov Methods, Kobby Essien

Dartmouth College Undergraduate Theses

The plethora of genomic data currently available has resulted in a search for new algorithms and analysis techniques to interpret genomic data. In this two-fold study we explore techniques for locating critical amino acid residues in protein sequences and for estimating the similarity between proteins. We demonstrate the use of the Short-Time Fourier Transform and the Continuous Wavelet Transform together with amino acid hydrophobicity in locating important amino acid domains in proteins and also show that the Kolmogorov-Smirnov statistic can be used as a metric of protein similarity.

Alfalfa Production And Pest Management In South Dakota, Mike Catangui, Martin Draper, Leon Wrage, Darrell Deneke

SDSU Extension Special Series

Alfalfa is a herbaceous perennial forage crop in the plant family Medicago. Alfalfa is well adapted to growing conditions in South Dakota if a variety with good winter hardiness has been selected. Several vegetative stems are produced from the crown during each growth cycle, and the plant has a deep, branched taproot system that allows it to produce acceptable forage yields, even under relatively dry conditions.
South Dakota is one of the leading alfalfa growing states in the U.S., annually producing more than six million tons of alfalfa hay for all uses.

Transmission Of Porcine Reproductive And Respiratory Syndrome Virus By Semen Is Dose Dependent, C.D. Nelson, R.R. Rowland, D.A. Benfield

South Dakota Swine Research Report, 2001

Procine reproductive and respiratory syndrome virus (PRRSV) is transmitted through semen via natural mating or atrificial insemination. However, the minimal infective dose of PRRSV required to effect transmission through semen is not known. In this study, we induced estrus in PRRSV seronegative gilts and then artificially inseminated these animals with extended, commercial boar semen “seeded” with difference concentrations (2, 20, 200, 2,000, 20,000, 200,000, or 2,000,000 TCID50/50 ml of semen) of the PRRSV isolate SD 92-23983. Infection of gilts by PRRSV was confirmed by weekly bleedings of these animals to detect serconversion using the commercial IDEXX ELISA. All pigs (n=7) …

Timing Of New Black Box Warnings And Withdrawals For Prescription Medications, Karen Lasser, Paul D. Allen, Steffie Woolhandler, David U. Himmelstein, Sidney M. Wolfe, David H. Bor

Publications and Research

Context Recently approved drugs may be more likely to have unrecognized adverse drug reactions (ADRs) than established drugs, but no recent studies have examined how frequently postmarketing surveillance identifies important ADRs.

Objective To determine the frequency and timing of discovery of new ADRs described in black box warnings or necessitating withdrawal of the drug from the market.

Design and Setting Examination of the Physicians' Desk Reference for all new chemical entities approved by the US Food and Drug Administration between 1975 and 1999, and all drugs withdrawn from the market between 1975 and 2000 (with or without a prior black …

An Interview With Tom Wessels, Patrick K. Pryor

Taproot: A Journal of Outdoor Education

Associate Editor of Taproot, Patrick Pryor, interviewed Tom Wessels, author of two books, Reading the Forested Landscape: A Natural History of New England and The Granite Landscape: A Natural History of America's Mountain Domes, from Acadia to Yosemite. Tom is also Director of the Masters Degree Program in Environmental Biology, at Antioch New England Graduate School. At Antioch he helped develop the Environmental Biology program that trains field ecologists to conduct research for non-profit, environmental organizations. He is also an Ecological Consultant for The Rain Forest Alliance's Smart Wood Program where he has developed "green certification" assessment· guidelines for timber …

The Obesity Epidemic: Characteristics Of Successful Weight Management Programs And Colorado's Approach, Michele Singer

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Obesity is rapidly growing in the United States with no sign of decreasing with current treatment options available to Americans (1). There are many treatments for obesity, but few are effective. The State of Colorado has numerous community nutrition programs available to its residents ranging from government programs such as universities and state health departments to healthcare providers and volunteer organizations such as the American Heart Association. Current treatments that are available for overweight and obese individuals include commercial programs, popular diet books, Internet programs, and individualized counseling. This paper will discuss different treatments and their efficacy, successful weight loss …

The Influence Of Religiosity And Fundamentalism On White Protestants' Attitudes Toward Women's Issues, Ashley Foster

Masters Theses & Specialist Projects

This study examines factors of religiosity and fundamentalism that lead to sexist attitudes toward various women's issues. Analysis of data from the 1996 General Social Survey was implemented to ascertain the dependent variables: the Attitude toward Abortion Scale, the Women in Politics Scale, the Familial Roles Scale, the Attitude toward the Women's Movement Scale, Biology as a Reason for Women Taking Care of Children, God's Will as a Reason for Women Taking Care of Children, Importance of Women's Issues and Self-report Being Feminist. The correlations and regressions between measures of religiosity (church attendance and strength of affiliation) and attitudes toward …

Myriophyllum Spicatum Invasion In Cave Run Lake, Kentucky, Rob A. Tewes

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science by Rob A Tewes on May 1, 2002.

Issue 18, David Bell

NoteBooth

New Booth Library opens; Teachers' Center offers collections and workshops; New librarians Stacey Knight-Davis (Reference) and Sarah Nesbeltt (Reference).

Mutagenesis Induced By The Tumor Microenvironment: Implications Of Increased Dna Damage And Diminished Dna Repair, Jianling Yuan

Yale Medicine Thesis Digital Library

Tumors are characterized by microenvironmental heterogeneity, with regions of hypoxia, low pH, and nutrient deprivation. It has been proposed that such conditions may be an important factor contributing to cancer genetic instability. Using a chromosomally based lambda phage shuttle vector as a mutation reporter, we show that growth of cells in hypoxia and/or at low pH results in elevated mutation frequencies in two different reporter genes. To elucidate the mechanism of the tumor microenvironment-induced genetic instability, we first measured the production of DNA damage upon hypoxia and re-oxygenation in culture. We found that under such conditions, the intracellular level of …

Kentucky Warbler (Vol. 78, No. 2), Kentucky Library Research Collections

The Kentucky Warbler

No abstract provided.

Hsc E-News., Health Sciences Center, Stony Brook University.

HSC E-News

No abstract provided.

Keynote Address: River Management Society Symposium, Cecil D. Andrus

Research and Reports

No abstract provided.

The Probe, Issue 222 – May/June 2002

The Probe: Newsletter of the National Animal Damage Control Association

Forging a New Partnership for the Public TrUSt: Wildlife Professionals & the Nuisance Wildlife Control Industry -- Lynn Braband
What is the risk of rabies from rodents?
10th Wildlife Damage Management Conference: April 6-9, 2003, Clarion Resort on the Lake, Hot Springs, Arkansas
Book Review: Resolving Human-Wildlife Conflicts: The Science of Wildlife Damage Management by Michael Conover.
CDC Emerging Zoonotic Concern in the Form of a Parasitic Roundworm -- Justin Harrington
Colorado's Boulder County has approved a new grasslands management plan that includes a provision to feed unwanted prairie dogs to blackfooted ferrets and raptors.
A bill being drafted in …

Species-Specific Identification Of Commercial Probiotic Strains, Marie Yeung, M. E. Sanders, Christopher L. Kitts, Raul Cano, Phillip S. Tong

Biological Sciences

Products containing probiotic bacteria are gaining popularity, increasing the importance of their accurate speciation. Unfortunately, studies have suggested that improper labeling of probiotic species is common in commercial products. Species identification of a bank of commercial probiotic strains was attempted using partial 16S rDNA sequencing, carbohydrate fermentation analysis, and cellular fatty acid methyl ester analysis. Results from partial 16S rDNA sequencing indicated discrepancies between species designations for 26 out of 58 strains tested, including two ATCC Lactobacillus strains. When considering only the commercial strains obtained directly from the manufacturers, 14 of 29 strains carried species designations different from those obtained …

Strategic Environmental Policy And International Trade In Asymmetric Oligopoly Markets, Yann Duval, Stephen F. Hamilton

Economics

This paper examines optimal cooperative and non-cooperative environmental taxes for the case in which a polluting input is used to produce an internationally-traded finished product. The model allows for terms-of-trade effects under oligopoly and employs a general specification of the environmental damage function that encompasses special cases of local, global, and transboundary externalities. The model has several implications for public finance. For example, inefficiently high environmental taxes may be optimal for a net exporting country in non-cooperative circumstances, as the motive to shift rent by selecting an inefficiently low tax rate is countervailed by the incentive to shift the burden …

Effect Of Diet Complexity And The Additive Effect Of Pharmacological Levels Of Zno And Carbadox On The Performance Of Weaned Pigs, D.Y. Lee, G.W. Libal, C.R. Hamilton, D.N. Peters

South Dakota Swine Research Report, 2001

The scientific literature documents the efficacy of antibacterial feed additives for weaned pigs. More recently, Feeding therapeutic levels of supplemental zinc (Zn) from zinc oxide (ZnO) stimulated voluntary feed intake and weight gain of young pigs. Over the last decade, research demonstrated that swine diets contianing sub-therapeutic levels of various antibiotics combined with pharmacological levels of copper (Cu) resulted in better performance than when either ingredient was provided individually. In 1982, an additive improvement in performance was found when a sub-therapeutic level (55 mg/kg) of carbodox (CARB) and high level of Cu (125 mg/kg) were provided in combination in a …

Community-Level Effects Of Clearcutting And Wildfire On Shrews, Grasshoppers, And Ground-Dwelling Beetles, J. Creed Clayton

Biology

Timber harvesting is often proposed as a substitute for stand-replacing wildfire; many feel such a controlled disturbance plays a similar ecological role to the natural disturbance of fire. In order to gain more insight into the soundness of this management approach, ground-dwelling beetles (Coleoptera), grasshoppers, crickets, and allies (Orthoptera), and shrews (Insectivora: Soricidae) were sampled by pitfall trap in recently burned, clearcut, and undisturbed forested plots (controls) near Logan, Utah. Over 200 beetle species from 39 families were included in the study. Nine orthopteran and two shrew species were included as well. Beetle abundance was reduced after burning and clearcutting, …

Yeast Ph Domains: A Study In Phosphoinositide Binding, Heather Leigh Eisler

Biology

Phosphoinositides are membrane-associated phospholipids whose inositol head group can be reversibly phosphorylated. PH domains are known to bind phosphoinositides. Yeast PH domains YPR091C and YNL144C were examined for their phosphoinositide binding using two different assays. The YPR091C PH domain bound specifically to PtdIns(4)P and PtdIns(5)P. The YNL144C PH domain did not bind to any phosphoinositide. The absence and the over expression of the YPR091C and YNL144C genes was studied in the yeast. The ypr091^CΔ strain grew slower at 37°C. The ynl144^CΔ yeast strain showed no growth defect at 37°C, higher salt concentrations, or when transformed with …

Report To Congress: Operations Of Glen Canyon Dan Pursuant To The Grand Canyon Protection Act Of 1992, Water Years 1999-2001, Secretary Of The Interior

All U.S. Government Documents (Utah Regional Depository)

Section 1804(c)(2) of the Grand Canyon Protection Act (GCPA) of 1992 requires the Secretary of the Interior (Secretary) to: . . . transmit to the Congress and to the Governors of the Colorado River Basin States a report, separate from and in addition to the report specified in section 602(b) of the Colorado River Basin Project Act of 1968, on the preceding year and the projected year operations undertaken pursuant to this Act. This report responds to the above-cited reporting requirements. The report focuses on Glen Canyon Dam operations for water years 1999 through 2001, projected dam operations for water …

Portland State Magazine, Portland State University. Office Of University Communications

Portland State Magazine

PSU’s alumni magazine, published 2-3 times a year. In this issue: Students make amazing creative leaps with digital graphics; the fall of Enron casts a spotlight on honesty in business; wires, sensors, and cameras help unclog the nation’s highways; for Ray Grimsbo ’72, the challenge of forensic science is looking beyond the obvious; and more.

Residential Radon Exposure And Lung Cancer: Variation In Risk Estimates Using Alternative Exposure Scenarios, R. William Field, Brian J. Smith, Daniel J. Steck, Charles F. Lynch

Physics Faculty Publications

The most direct way to derive risk estimates for residential radon progeny exposure is through epidemiologic studies that examine the association between residential radon exposure and lung cancer. However, the National Research Council concluded that the inconsistency among prior residential radon case-control studies was largely a consequence of errors in radon dosimetry. This paper examines the impact of applying various epidemiologic dosimetry models for radon exposure assessment using a common data set from the Iowa Radon Lung Cancer Study (IRLCS). The IRLCS uniquely combined enhanced dosimetric techniques, individual mobility assessment, and expert histologic review to examine the relationship between cumulative …

Rnaml: A Standard Syntax For Exchanging Rna Information, Neocles B. Leontis, Allison Waugh, Patrick Gendron, Russ Altman, James W. Brown, David Case, Daniel Gautheret, Stephen C. Harvey, John Westbrook, Eric Westhof, Michael Zuker, François Major

Chemistry Faculty Publications

Analyzing a single data set using multiple RNA informatics programs often requires a file format conversion between each pair of programs, significantly hampering productivity. To facilitate the interoperation of these programs, we propose a syntax to exchange basic RNA molecular information. This RNAML syntax allows for the storage and the exchange of information about RNA sequence and secondary and tertiary structures. The syntax permits the description of higher level information about the data including, but not restricted to, base pairs, base triples, and pseudoknots. A class-oriented approach allows us to represent data common to a given set of RNA molecules, …

The Deaf Catholic, May-June 2002

ICDA The Deaf Catholic

A newsletter published for Deaf Catholics in USA

ICDA The Deaf CatholicFinding Aid

The Role Of Injury And Rain In The Infection Of Leaves By Erwinia Amylovora, Scott C. Ockey

Biology

Erwinia amylovora dissemination was studied by sampling apple and pear leaves before and after a precipitation event. All pear and apple experiments revealed similar trends for the temporal and spatial nature of E. amylovora. Rain dispersed the bacteria to leaves only a short distance from the infection and survived less than 24 hours on the leaf. An experiment was designed to determine leaf age susceptibility to inoculation by E. amylovora when leaves were subjected to injury types that simulated hail, wind-blown rain, and rain dispersal. Succulent leaves in the hail and rain dispersal treatments were more susceptible to infection …

Processes For The Allocation, Reallocation And Governance Of Resource Access In Connection With A Framework For The Future Management Of Fisheries In Western Australia, Government Of Western Australia Department Of Fisheries

Fisheries Management Papers

This paper outlines the issues associated with developing a framework to deal explicitly with the allocation, reallocation and the governance of access to the fisheries resources of Western Australia.

Resources, Coalition For Education In The Outdoors

Taproot: A Journal of Outdoor Education

This section contains a listing of teaching resources of all types for those who work in the outdoor education field at the time of publication. Some items highlighted include: Forestry Suppliers' Geology F.I.E.L.D. Kit TM and the Landscape of America, a book by May Theilgaard Watts.

Lady Macbeth And Gertrude: A Study In Gender, Lisa Ferguson

Masters Theses & Specialist Projects

The detailed examination of two of Shakespeare's female leads, Lady Macbeth and Gertrude, is designed to determine whether or not these particular characters were free from the confines of their society, or if they were content within its oppressive grasp. A combination of Feminist Criticism and New Historicism reveals that Lady Macbeth and Gertrude did not overstep the bounds of their gender, but in fact were suppressed within them. The limited rights and freedoms of a woman during the Renaissance is heavily discussed, and aids in giving the reader a vivid impression of Lady Macbeth's and Gertrude's subjugation. As Renaissance …

Threshold Evolution In Exotic Populations Of A Polyphenic Beetle, Armin P. Moczek, John Hunt, Douglas J. Emlen, Leigh W. Simmons

Biological Sciences Faculty Publications

Polyphenic development is thought to play an important role in the evolution of phenotypic diversity and morphological novelties, yet the evolution of polyphenisms has rarely been documented in natural populations. Here we compare the morphologies of male dung beetles (Onthophagus taurus; Coleoptera: Scarabaeidae) from populations introduced to Australia and the eastern United States. Males in this species express two alternative morphologies in response to larval feeding conditions. Males encountering favourable conditions grow larger than a threshold body size and develop a pair of horns on their heads, whereas males that encounter poor conditions do not reach this threshold size and …

The Fitness Consequences Of Interspecific Eavesdropping Between Plants, Richard Karban, John L. Maron

Biological Sciences Faculty Publications

Although many ecologists have discounted the possibility of communication between plants, recent work demonstrates that wild tobacco plants with experimentally clipped sagebrush neighbors suffer less leaf herbivory than tobacco controls with unclipped neighbors. In this report, we examine the fitness consequences of resistance induced by eavesdropping. Annual tobacco plants with clipped sagebrush neighbors produced more flowers and seed-bearing capsules than plants with unclipped neighbors although these performance measures varied considerably over the five years of the study. Tobacco plants with clipped neighbors also suffered more frost damage than controls in one year. There was no indication that eavesdropping was more …