Digital Commons Network^™

Increased Production Of Pro-Inflammatory Cytokines And Enhanced T Cell Responses After Activation Of Human Dendritic Cells With Il-1 And Cd40 Ligand, Amy Wesa, Anne Galy

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Various microbial, inflammatory and immune signals regulate the activation of dendritic cells (DC), determining their ability to interact with naïve T cells and to produce cytokines that direct T cell development. In particular, CD40L and IL-1 cooperatively activate DC to secrete high levels of IL-12. The immuno-stimulatory capacity of such DC is otherwise not well-defined prompting further characterization of the effects of IL-1 and family members on DC activation in comparison with other pro-inflammatory stimuli.

Results

Human DC co-activated in vitro by CD40L and IL-1β expressed numerous cytokine genes including IL-12β, IL-23 p19, IL-1β, IL-1α, IL-1Ra, IL-10, IL-6, …

Search For Intracranial Aneurysm Susceptibility Gene(S) Using Finnish Families, Jane M. Olson, Sompong Vongpunsawad, Helena Kuivaniemi, Antti Ronkainen, Juha Hernesniemi, Markku Ryynã¤Nen, Lee-Lian Kim, Gerard Tromp

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Cerebrovascular disease is the third leading cause of death in the United States, and about one-fourth of cerebrovascular deaths are attributed to ruptured intracranial aneurysms (IA). Epidemiological evidence suggests that IAs cluster in families, and are therefore probably genetic. Identification of individuals at risk for developing IAs by genetic tests will allow concentration of diagnostic imaging on high-risk individuals. We used model-free linkage analysis based on allele sharing with a two-stage design for a genome-wide scan to identify chromosomal regions that may harbor IA loci.

Methods

We previously estimated sibling relative risk in the Finnish population at between …

Arms Control And National Security, John R. Burroughs, Jonathan Granoff, John H. Harrington, Bonnie D. Jenkins

The International Lawyer

No abstract provided.

Ifn-G-Mediated Transcriptional Induction Of The Ido (Indolamine 2,3-Dioxygenase) Gene Requires Activity Of P68/Pkr Protein Kinase, Ni̇lüfer Gülmen İmi̇r, Ayşegül Nasircilar, Hakan Akça, Teki̇nalp Gelen, Mehmet Öğüş, Şeyda Karaveli̇, Osman Ni̇dai̇ Özeş

Turkish Journal of Medical Sciences

We investigated whether the activity of double-stranded RNA activated kinase (p68/PKR) is necessary for induction of IDO (indolamine 2,3 -dioxygenase) gene by IFN-\gamma. For this purpose, we planned to abrogate the function of cellular wt-PKR gene. Clones of ME180 cells expressing the dominant negative form of PKR were selected in the presence of neomycin. Then these cells were treated with IFN-\gamma and accumulation of IDO protein was determined by Western blot analysis. We found that clones expressing the dominant negative form of the PKR gene were not only resistant to IFN-\gamma-mediated killing, but were also incapable of inducing accumulation of …

Faculty Profiles And Publications 2002, Wiener-Rogers Law Library, University Of Nevada, Las Vegas -- William S. Boyd School Of Law

Faculty

No abstract provided.

The Extension Newsletter, Issue 37, Winter Quarter 2002, Wright State University Retirees Association

The Extension Newsletter

An eight page newsletter from the Wright State University's Retirees Association.

Vicarious Traumatization And Its Impact On The Pennsylvania Child Welfare System, Jo Ann Jankoski

Electronic Theses and Dissertations

Although many studies have addressed burnout, secondary trauma, and job satisfaction among child welfare workers throughout the United States, a review of the current and available literature revealed limited research addressing the impact of vicarious trauma and its relationship to worker retention, recruitment, and job satisfaction. This study was conducted within the context of traumatology theory and examined how vicarious trauma affects child welfare workers and to what degree vicarious trauma has had an impact on their collective community, the child welfare system. The research question that guided this study was: How does vicarious trauma affect child welfare workers and …

An Examination Of The Development Of Personal Power Among Trainees At Various Stages Of The Counselor Education Process, John Welburn

Electronic Theses and Dissertations

The study investigated the effect that participation in counselor training had on the personal power levels of 45 student volunteers representing three levels of counseling training. Group I (Beginning level) consisted of 15 students beginning counselor training, Group II (Practicum level) was comprised of 16 students beginning the practicum experience, and Group III (Graduating level) was consisted of 14 students graduating from the counselor training program. Individual assessment of personal power levels was accomplished utilizing Hagberg's Personal Power Profile, a 72 question instrument designed to measure individual personal power levels. The six stages of personal power that the instrument is …

Executive Orders, The Very Definition Of Tyranny, And The Congressional Solution, The Separation Of Powers Restoration Act, Leanna M. Anderson

UC Law Constitutional Quarterly

James Madison wrote, "The accumulation of all powers, legislative, executive, and judiciary, in the same hands... may justly be pronounced the very definition of tyranny." The Federalist No. 47, at 300 (James Madison) (Henry Cabot Lodge ed., 1888). Expansive executive orders are often criticized as the merger of legislative and executive powers in the hands of the President. This Note examines how the judiciary has worked to check this "tyranny." After examining the difficulties in challenging executive orders, this Note examines how the proposed Separation of Powers Restoration Act would facilitate legal challenges to executive orders.

2002 Transactions, American Dental Association

ADA Transactions

This item is part of the Transactions of the ADA, a serial publication of the annual activities of the ADA House of Delegates (HOD)/Board of Trustees (BOT). It is from the Transactions section, one of three subtitles that make up the full publication. Generally, the ADA Transactions are published in multiple volumes throughout the year. Pages from the Annual Reports and the Transactions are numbered consecutively (e.g. Annual Reports volume ends pg. 500 and Transactions volume starts at pg. 501). NOTE: All three subtitles are collectively known as the Transactions of the ADA or, alternatively, the ADA Transactions. Transactions refers …

2002 Annual Reports And Resolutions, American Dental Association

ADA Transactions

This item is part of the Annual Reports and Resolutions subtitle of the ADA Transactions, a serial publication of the annual activities of the ADA House of Delegates (HOD)/Board of Trustees (BOT) made up of three separate subtitles: Annual Reports and Resolutions, Supplements, and Transactions. Generally, the ADA Transactions are published in multiple volumes throughout the year. Older versions include reports from all departments as subsections, while more recent versions include only those of councils, commissions, and committees.

Tampa Bay Region Economic Market Report, Tampa Bay Partnership, University Of South Florida. Center For Economic Development Research

College of Business Publications

Tampa Bay Market Report 2002 -- Executive Summary -- Tampa Bay's Workforce -- Wages and Income -- Business and Economic Conditions -- Education Indicators.

Comparison Of Antibiotic Resistance Patterns Of Uropathogenic Escherichia Coli In Outpatient And Inpatient Populations From 1990 To 1996 In Bemidji, Mn, Gail R. Conway, Patrick Guilfoile

Journal of the Minnesota Academy of Science

A retrospective study of antibiotic susceptibility was conducted on data from all uropathogenic Escherichia coli submitted to the MeritCare Clinic-Bemidji, MN and the North Country Regional Hospital-Bemidji, MN during 1990, 1993, and 1996. The proportion of antibiotic resistant strains was generally equal or higher in E. coli isolates from community-acquired infections than with E. coli isolates from nosocomial infections. Comparison with antibiotic prescriptions during 1990, 1993, and 1996 provided no clear relation between antibiotics prescribed for outpatient urinary tract infections and the proportion of E. coli strains resistant to those antibiotics. This suggests that factors other than selection for resistance …

Employer Perceptions Of Work Flexibility: Role Of Skills And Wages In Job Performance, Raymond L. Raab, Pradeep Kotamraju, Maureen O'Brien

Journal of the Minnesota Academy of Science

A programming approach, data envelopment analysis (DEA), will sort and rank occupations on the basis of maximizing skills required and minimizing that occupation's wage resulting in a set of "hiring" efficiency scores. This procedure improves Borda rankings (rankings based on the average of rankings of the individual components), fixed weight, or subjective weighting schemes. In DEA, the linear programming weights or coefficients are explicitly chosen to maximize the discrimination between the skills and wages. A rank correlation between the efficiency scores and various work and demographic variables is performed. The results show a negative correlation between the wage rate and …

Abstracts For The 70th Annual Meeting

Journal of the Minnesota Academy of Science

No abstract provided.

Ay 2001/2002 Election Nomination Form, Faculty Senate

Faculty Senate Archives

No abstract provided.

Self -Determination And Success Outcomes Of Two -Year College Students With Disabilities: An Integration Of Quantitative And Qualitative Approaches, Deborah Russo Jameson

Doctoral Dissertations

Two recent movements have occurred in the name of equality of opportunity in a democratic America: the Disabilities Movement in higher education where increasing numbers of students with disabilities are enrolling in college; and the Self-Determination Movement (Wehmeyer, 2000; Ward & Meyer, Fall, 99) as it relates to transition initiatives and positive adult outcomes for individuals with disabilities. To date, the Self-Determination Movement has made few in-roads into higher education, and a relationship between the success of college students with disabilities and self-determination remains largely untested.

The purpose of this study was to investigate a possible relationship between post-secondary success …

A Focus On Human Resource Management Practices After The Attacks On September 11th, 2001, Erin Stauffer

Honors Capstones

This thesis concerns Human Resource Management practices after the terrorist attacks on September 11th 2001. It is divided into three main sections. The first section describes expert opinions on various topics. Those topics include emergency procedures for handling Anthrax contamination and preventative mail handling procedures. Recommendations on plans of evacuation and emergency revival procedures are given along with information about implementing an effective security system. Employee Assistance Programs are discussed and harassment policies and diversity training issues are examined due to the unfortunate backlash against Muslim workers since to the attacks. The second section analyzes real life data obtained from …

Faculty Senate Librarian's Report-2002, Georgia Southern University

Faculty Senate: Librarian's Reports

No abstract provided.

Nonactin Biosynthesis : Studies Toward The Synthesis Of Stable Isotope Labeled Potential Precursors, Melanie Bengtson

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

University Place

Syracuse University Magazine

No abstract provided.

Su People

Syracuse University Magazine

No abstract provided.

Time For Action, Margaret Costello

Syracuse University Magazine

No abstract provided.

Alumni News & Notes

Syracuse University Magazine

No abstract provided.

Quad Angles

Syracuse University Magazine

No abstract provided.

University Place

Syracuse University Magazine

No abstract provided.

Acid Rain Man, Christine Yackel

Syracuse University Magazine

No abstract provided.

Holding On, Paula Meseroll

Syracuse University Magazine

No abstract provided.

Su People

Syracuse University Magazine

No abstract provided.

Safety On The Hill, Margaret Costello

Syracuse University Magazine

No abstract provided.