Digital Commons Network^™

Obstacles In Recruiting African Americans For Clinical Trials., Betty Monroe Kennedy

LSU Historical Dissertations and Theses

Previous abusive clinical trials have caused several obstacles in recruiting African Americans for clinical trials today. The memory of the Tuskegee Syphilis Study alone remains a hard pill to swallow and is a constant hindrance to recruiting potential African Americans specifically males, for clinical trials. The basic trust that African Americans have for physician researchers, U.S. government doctors, U.S. government-sponsored research, and biomedical research in general has been seriously, although not irrevocably, breached. The purpose of this study was to gain an understanding of the knowledge, attitudes, and beliefs African Americans have that support decisions to either participate or not …

Anatomical Variations Of Internal Jugular Vein As Seen By "Site Rite Ii" Ultrasound Machine--An Initial Experience In Pakistani Population, Hameedullah, M. A. Rauf, Fazal Hameed Khan

Department of Anaesthesia

Objective: To determine the anatomical variations of the internal jugular vein (IJV) in Pakistani adult population with the help of Site Rite II ultrasound machine.
Material and Method: The right IJV relation to the carotid artery was visualized at four different landmarks (angle of the mandible, thyroid cartilage, cricoid cartilage, and the supraclavicular area). Size of IJV in comparison to carotid artery was also seen.
Results: In 49 cases the IJV was found in aberrant relation to carotid artery at the angle of the mandible (p value
Conclusion:Care should be taken while cannulating IJV at the angle of the …

Removing Dam Development To Recover Columbia Basin Treaty Protected Salmon Economies, Rollie Wilson

American Indian Law Review

No abstract provided.

These Tough Kids : Echoes From The State Orphans' Home, Susan Fogarty Schwab

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

Persistent Productive Epstein‐Barr Virus Replication In Normal Epithelial Cells In Vivo, Dennis M. Walling, Catherine M. Flaitz, C. Mark Nichols, S. David Hudnall, Karen Adler-Storthz

Faculty, Staff and Student Publications

Productive Epstein‐Barr virus (EBV) replication characterizes hairy leukoplakia, an oral epithelial lesion typically occurring in individuals infected with human immunodeficiency virus (HIV). Serial tongue biopsy specimens were obtained from HIV‐infected subjects before, during, and after valacyclovir treatment. EBV replication was detected by Southern hybridization to linear terminal EBV genome fragments, reverse‐transcriptase polymerase chain reaction amplification of EBV replicative gene transcripts, immunohistochemical detection of EBV replicative protein, and in situ hybridization to EBV DNA. EBV replication was detected in both hairy leukoplakia and normal tongue tissues. Valacyclovir treatment completely abrogated EBV replication in vivo, resulting in resolution of hairy leukoplakia when …

Breastfeeding In The American Workplace, Shana M. Christrup

American University Journal of Gender, Social Policy & the Law

No abstract provided.

A Low-Cost Intervention For Cleaner Drinking Water In Karachi, Pakistan, S Luby, M Agboatwalla, A Raza, J Sobel, E Mintz, K Baier, M Rahbar, S Qureshi, Rumina Hassan, F Ghouri

Community Health Sciences

Objective: To pilot test an inexpensive, home-based water decontamination and storage system in a low-income neighborhood of Karachi.Methods: Fifty households received a 20-L plastic water storage vessel with a high-quality spout and a regular supply of diluted hypochlorite solution. Twenty-five control households were recruited. Water samples were collected at baseline and during unannounced follow-up visits 1, 3, 6, and 10 weeks later.Results: Baseline drinking water samples among intervention households were contaminated with a mean 9397 colony-forming units (cfu)/100 mL of thermotolerant coliforms compared with a mean 10,990 cfu/100 mL from controls. After intervention the mean concentration of thermotolerant coliforms decreased …

Kenneth W. Gibb V. Earl N. Dorius : Response To Petition For Rehearing, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

PETITION FOR REHEARING FROM THE DECISION OF THE SUPREME COURT OF UTAH SUSTAINING THE JUDGMENT OF THE THIRD JUDICIAL DISTRICT COURT, IN AND FOR SALT LAKE COUNTY, STATE OF UTAH, THE HONORABLE D. FRANK WILKINS, JUDGE, PRESIDING.

Sherry Jensen And Shayne Hipwell, Individually, And On Behalf Of All Other Heirs Of Shelly Hipwell, And Ashley Michele Hipwell And Kaycie Shaylene Hipwell Appearing By Shayne Hipwell As Guardian Ad Litem, V. Ihc Hospitals, Inc., Dba Mckay-Dee Hospital, Michael J. Healy, M.D., And Does I Through X : Brief Of Appellee, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

APPEAL FROM A JUDGMENT OF THE THIRD DISTRICT COURT, THE HONORABLE GLENN K. IWASAKI

Eradication Of Biofilm-Forming Staphylococcus Epidermidis (Rp62a) By A Combination Of Sodium Salcylate And Vancomycin, Roy E. Polonio, Leonard A. Mermel, Gregory E. Paquette, Jay F. Sperry

Past Departments Faculty Publications (CELS)

Staphylococcus epidermidis is a major cause of infections associated with indwelling medical devices. Biofilm production is an important virulence attribute in the pathogenesis of device-related infections. Therefore, elimination of these biofilms is an ideal treatment. Salicylate (5 mM) combined with 1 μg of vancomycin per ml inhibited biofilm formation by S. epidermidis (RP62A) by ≥99.9%. When biofilm-coated polystyrene beads were exposed to 5 mM sodium salicylate and 4 μg of vancomycin per ml (one-half the minimum biofilm eradication concentration), there was a >99.9% reduction in viable count.

Cytokine Regulation Of Class Ii Mhc And Ciita Expression In Astrocytes., Yuanshu Dong

All ETDs from UAB

No abstract provided.

Social Consequences Of Place: An Examination Of Social Capital And Well -Being In The Inner City., Carey Usher Mitchell

All ETDs from UAB

No abstract provided.

Molecular Interactions Involved In The Assembly And Entry Of Mason -Pfizer Monkey Virus., Chisu Song

All ETDs from UAB

No abstract provided.

City Against Suburb: The Culture Wars In An American Metropolis [Book Review], Stephen J. Mcgovern

Political Science Faculty Scholarship

Review of City Against Suburb: The Culture Wars in an American Metropolis by Joseph A. Rodriguez.

Activist Advertising: Case Studies Of United Colors Of Benetton's Aids -Related Company Promotion., Heidi Jolene Brough

LSU Historical Dissertations and Theses

This study explores how advertising and company promotion may be used to address social issues. In particular, I examine how the clothing company United Colors of Benetton attempted to position itself within the AIDS crisis. Specifically, this study investigates through case studies how the Benetton Group used activist advertising and company promotion to bring about social change concerning AIDS-related issues. I also attempt to account for the controversy that the promotion elicited through establishing the anomalous status of the company's promotion within traditional advertising efforts. The study begins with information concerning the AIDS crisis and AIDS activism and then moves …

Jorgenson V. Vener: The South Dakota Supreme Court Declares Loss-Of-Chance Doctrine As Part Of Our Common Law In Medical Malpractice Torts, Shawn M. Nichols

South Dakota Law Review

No abstract provided.

Blood Serum Concentrations Of Selenium And Glutathione Peroxidase Activity In Akkaraman Sheep, Taner Pamukçu, Tevhi̇de Sel, Gül Yarim

Turkish Journal of Veterinary & Animal Sciences

Selenium and other essential elements play an important role in animal husbandry. These elements help to minimize infectious diseases, reduce concomitant stresses and bring about optimal productive and reproductive performance. The mean serum selenium concentration of the sheep sampled in this study was 303.65 ng/ml. Such values are considered to be indicative of adequate dietary supplementation. Serum glutathione peroxidase activity in the sheep sampled in this study was also analysed, and the mean glutathione peroxidase activity was 3.65 nmolNADPH+H+/min/mg protein. It is recommended that producers monitor the selenium in serum in order to maintain adequate nutrition and performance in sheep.

Acute Haemolysis In Childhood Falciparum Malaria, H. Ekvall, P. Arese, F. Turrini, K. Ayi, F. Mannu, Zul Premji, A. Bjorkman

Pathology, East Africa

Acute haemolysis associated with clinical episodes of high-level Plasmodium falciparum parasitaemia was studied in 20 children from an holoendemic area (coastal Tanzania). The change in blood haemoglobin (Hb) concentration ranged from -46 to +5 g/L during the 72-h observation period and was linearly related to maximum parasitaemia. Balance studies between loss of blood Hb, increase in plasma Hb and appearance of Hb in the urine indicated that extravascular clearance of red cells was the predominant mode of erythrocyte clearance. Most subjects, however, showed minor signs of intravascular haemolysis. The plasma Hb was ≪1% of blood Hb and haemoglobinuria was detected …

Hemoglobin Concentration In Children In A Malaria Holoendemic Area Is Determined By Cumulated Plasmodium Falciparum Parasite Densities, H. Ekvall, Zul Premji, S. Bennett, A. Bjorkman

Pathology, East Africa

In malaria holoendemic areas children are anemic, but the exact influence of falciparum malaria on hemoglobin (Hb) concentration remains largely unsettled. Prospective data were therefore collected in children < 24 months of age during five months in a Tanzanian village. Children with mean asymptomatic parasitemia ≥ 400/μl had lower median Hb levels during the study than those with mean density < 400/μl. The difference was 9.7 g/L (95% confidence interval [CI] 2.8-17). In children with one or more clinical malaria episodes, the median Hb was 8.3 g/L (95% CI 0.9-16) lower than those without episode. If early treatment failure was recorded, the immediate effect on Hb was particularly important with a mean drop of 17 g/L. Interestingly, at study-end the Hb concentration represented a function of the area under the parasitemia curve (AUPC) during the previous five months, adjusting for age. In conclusion, stepwise deterioration in median Hb levels was found by asymptomatic parasitemia, clinical malaria episode, and most significantly, treatment failure.

Examining The Need For Improved Health Education For Underserved Populations In Selected Eastern Caribbean Basin Nations, Linda K. George Miller

Graduate Research Papers

The Eastern Caribbean Basin (ECB) is comprised of several diverse islands that share many common characteristics. As tourism has increased in most of the islands, chronic disease patterns have also increased. The governments of these island nations are well aware of the need for increased health education efforts, but adequate personnel are not always available locally.

Complications from chronic disease are escalating in the aging population. Efforts to expand health education efforts among the islands would assist in reducing these complications and early deaths.

Diseases often seen on the ECB islands include hypertension, cardiovascular and heart disease, diabetes, cancer, and …

Improved Compliance With Universal Precautions In The Operating Room Following An Educational Intervention, Lynn E. Kim, Donna B. Jeffe, Bradley A. Evanoff, Sunita Mutha, Brad Freeman, Victoria J. Fraser

Occupational and Health Faculty Publications

No abstract provided.

An Economic Analysis Of The Allocation Of Research Funding At The National Institutes Of Health., Janet B. Daniel

LSU Historical Dissertations and Theses

Our model examines the allocation of medical research funds at the National Institutes of Health using public interest theory, incremental budgeting theory, and special interest group theory. We use the allocation of research funds among various diseases and measures of the burden of disease on the population to test the hypothesis that the N.I.H. is allocating funds on a pure public interest basis, to test for incremental budgeting effects, and to test for the influence of lobbying and other political variables representing special interest groups. We use pooled cross-sectional, time-series data in a one-way fixed effects model, and also use …

Inhibition Of Measles Virus Replication By 5'-Norcarbocyclic Nucleoside Analogs, Dale L. Barnard, V. Stowell, K. L. Seley, V. R. Hegde, R. Subha, P. Rajappan, S. W. Schneller, Donald F. Smee, R. W. Sidwell

Animal, Dairy, and Veterinary Science Faculty Publications

Despite intense efforts to increase vaccine coverage, measles virus (MV) still causes significant morbidity and mortality in the world, sometimes as the result of severe, chronic, lethal disease. In an effort to develop therapies to supplement immunization strategies, a number of 5′-nor carbocyclic adenosine analogues were evaluated for anti-MV activity in CV-1 monkey kidney cells. Of those compounds tested, those either unsubstituted at C4 or possessing a hydroxyl, azido or amino substituent at that position were the most active, with particularly significant inhibition of MV, strain Chicago-1. The EC50 values against this strain ranged from100 mg/ml in actively growing and …

Lifestyle Management: The Effects Of An Intensive Lifestyle Management Course On Behavioral, Psychological, Physiological, And Psycho-Behavioral Factors., Jeffrey Scott Pauline

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to evaluate the impact of an intensive one-week Lifestyle Management course on behavioral, psychological, physiological, and psycho-behavioral factors. The current study contained forty-five participants (N = 45) which included twenty-four individuals enrolled in the Lifestyle Management course (experimental group) and twenty-one matched individuals (control group). The experimental group experienced high-level wellness in the intensive one-week course of Lifestyle Management. The control group did not participate in the Lifestyle Management course or any other wellness course prior to the study. The experimental and control groups were evaluated at three time points: prior to entering the …

Field Methodology For The Determination Of The Prevalence Of Giardia Cysts And Cryptosporidium Oocysts Drinking Water And Its Association To The Development Of Diarrheal Disease In The Transylvania Region Of Romania, Rick J. Bauer

Dissertations and Theses @ UNI

The purpose of this study was to analyze the drinking water of 69 individuals living in the Transylvania region of Romania for the presence of Giardia cysts and Cryptosporidium oocysts. The ultimate objective was to determine if a correlation exists between the presence and concentrations of these two protozoa and the reported frequency and average severity of diarrheal disease in the study group members.

To accomplish this goal, a collection, emulsion, concentration, labeling, and identification method had to be developed that could operate effectively in an international field setting. The protocol selected included the collection of samples using a compressed …

Illinois State: For Alumni Of Illinois State University, Winter 2001-2002, Illinois State University, University Marketing And Communications

State: The Magazine of Illinois State University (1999-present)

Illinois State University alumni magazine

Hiv/Aids And Human Rights In Russia: Compliance And The Rule Of Law, William F. Flanagan

Osgoode Hall Law Journal

This article examines Russia’s legal response to its ongoing HIV/AIDS epidemic. Russia’s international human rights obligations are reviewed and the article then critically assesses the extent to which Russia’s current HIV/AIDS law and practice are consistent with those obligations. The paper demonstrates that most aspects of Russia’s HIV/AIDS laws are consistent with Russia’s international obligations. However, the paper also documents key parts of HIV/AIDS practice in Russia that are seriously inconsistent with both Russian HIV/AIDS law and Russia’s international human rights obligations. This inconsistency between HIV-related de jure norms and de facto practice raises the question of compliance with the …

A Report On Nurses' Response To Occupational Injuries And Exposures To Hazards In A Californian Community Hospital, Sandra Kilminster-Binder

Theses: Doctorates and Masters

This study set out to determine the reasons for underreporting of occupational injuries and exposures in the American health care environment. A cross sectional survey was used to report the responses and opinions of nurses who failed to report all occupational injuries and exposures, and the type of injuries that are least likely to be reported. The participants were a random sample of Registered Nurses employed in a California Health Care Center, who responded to a simple self-reporting questionnaire. The study revealed that the majority of occupational injuries, accidents and exposures by this group in the previous twelve month period …

Making Clinical Trials Safer For Human Subjects, Michael S. Baram

Faculty Scholarship

Clinical trials, in which new biotech and other medical products are tested on human subjects, provide much of the data used by the FDA to determine whether the products are suitable for routine use in health care. Thus, the trials are of obvious importance to medical progress and improvement of public health, and to those who have career and financial interests at stake. But clinical trials are also important to the human subjects involved because the products being tested on them may remedy their illnesses, but may also pose risks since the products have usually not been previously tested on …

Health Care, Technology And Federalism, Kevin Outterson

Faculty Scholarship

The regulation of health care has traditionally been the province of the states, most often grounded in the police power. In Colonial times, this division of responsibility was a rational response to the technological level of the eighteenth century, although even in the youth of the Republic some health and safety regulation required national and international action. With the growth of distancecompression technology, the increase in mobility of goods and services, and a significant federal financial role in health care, the grip of the police power on the regulation of health care has been weakened. Discussion of the police power …