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2000 Annual Report Of The Commissioners, Treasurer, Other County Officers And The Strafford County Delegation Strafford County, New Hampshire For The Year Ending December 31, 2000., Stafford County Representatives

Strafford County, NH Annual Reports

This is an annual report containing vital statistics for a county in the state of New Hampshire.

Interferon Regulatory Factor 7 Mediates Activation Of Tap-2 By Epstein-Barr Virus Latent Membrane Protein 1, Luwen Zhang, Joseph S. Pagano

Nebraska Center for Virology: Faculty Publications

Transporter associated with antigen processing 2 (Tap-2) is responsible for ATP-dependent transport of peptides from the cytosol to the endoplasmic reticulum, where peptides bind to newly synthesized human leukocyte antigen (HLA) class I molecules, which are essential for cellular immune responses. Epstein-Barr virus (EBV) latent membrane protein 1 (LMP-1) has been shown to induce the expression of Tap-2. In this study, the induction of endogenous Tap-2 by LMP-1 is shown to be associated with and requires the expression of interferon regulatory factor 7 (IRF-7). In DG75 Burkitt’s lymphoma (BL) cells, in which LMP-1 induces the expression of IRF-7, LMP-1 induced …

Serological Responses Of Coyotes To Two Commercial Rabies Vaccines, Frederick F. Knowlton, Marianna Roetto, Deborah Briggs

United States Department of Agriculture Wildlife Services: Staff Publications

Between August 1993 and September 1994 we documented serological responses of coyotes (Canis latrans) vaccinated with two commercial rabies vaccines licensed for use in domestic dogs. Serologic responses were documented by testing for rabies virus neutralizing antibodies with the rapid fluorescent focus inhibition test (RFFIT) at 30, 90, 180, 270, and 365 days post-vaccination. All coyotes vaccinated with Imrab 3^® (Rhone-Merieux, Inc.), and 75% of those vaccinated with Dura-Rab 3^® (Immunovet, Inc.) seroconverted, as evidenced by the presence of antirabies antibody titers ≥1:5 in one or more of the five post-vaccination samples. The percent of coyotes …

Synlophe In Ostertagia Cf. Kasakhstanica (Nematoda: Ostertagiinae), The Minor Morphotype Of O. Bisonis From Western North America, Eric P. Hoberg, Arthur Abrams

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Ostertagia cf. kasakhstanica. the putative minor morphotype of the polymorphie ostertagiine O. bisonis, is reported in Bison bison from South Dakota. Descriptions of the synlophe and details of other diagnostic characters useful in identification and differentiation of this minor morphotype from other ostertagiines in wild and domestic ruminants from western North America are presented. Laterally, the cervical synlophe is consistent with Type Ib pattern among ostertagiines and is within the range of variation previously described for O. bisonis. Among recognized minor morphotypes of ostertagiines in wild and domestic ruminants from North America, O. kasakhstanica is distinct from …

A New Lungworm In Muskoxen: An Exploration In Arctic Parasitology, Susan J. Kutz, Eric P. Hoberg, Lydden Polley

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Ruminants are vital elements of the Holarctic ecosystem. Little is known, however, of the structure or biology of their parasite fauna, particularly in North America. Global warming, coupied with increasing human activity in the Arctic, requires enhanced intemational interdisciplinary efforts to better understand the many factors, including parasites, that influence the population health of caribou, reindeer, muskoxen and wild sheep. The discovery of an unusual new genus of protostrongylid lung nematode in muskoxen from the central Canadian Arctic is described, and the intricacies of the parasite's relationship with its muskoxen definitive hosts, its gastropod intermediate hosts and the arctic environment …

New Host And Geographic Records For Two Protostrongylids In Dall's Sheep, Susan J. Kutz, A. M. Veitch, Eric P. Hoberg, B. T. Elkin, Emily J. Jenkins, L. Polley

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Biodiversity survey and inventory have resulted in new information on the distribution of Protostrongylidae in Dall’s sheep (Ovis dalli dalli) from the Northwest Territories (Northwest Territories, Canada) and from Alaska (Alaska, USA). In 1998, Parelaphostrongylus odocoilei adults were found for the first time in the skeletal muscles of Dall’s sheep in the Mackenzie Mountains (Northwest Territories). Adult P. odocoilei were associated with petechial and ecchymotic hemorrhages and localized myositis; eggs and larvae in the lungs were associated with diffuse granulomatous pneumonia. Experimental infections of the slugs Deroceras laeve and Deroceras reticulatum with dorsal-spined first-stage larvae assumed to be …

Are Saudi Arabian Hospitals Prepared For The Threat Of Biological Weapons?, Manuel W. Mah, Ziad A. Memish

Saudi Medical Journal

The use of biological weapons has been recorded repeatedly in history. Until recently, biological terrorism had been little discussed or written about. However, events over the past 12 to 18 months have made it clear that likely perpetrators already envisage every possible scenario. Nations and dissident groups exist that have both the motivation and access to utilize biological weapons. In April 1994, a Russian biological weapons expert presented the conclusions of the Russian experts as to the agents most likely to be used: smallpox, anthrax, and plague. Health care workers in the Kingdom of Saudi Arabia (physicians, nurses, and emergency …

Antibiotic Susceptibilities Of Helicobacter Pylori, Khalid M. Bindayna

Saudi Medical Journal

OBJECTIVE: The aim of this study was to evaluate the prevalence of resistance among 83 Helicobacter pylori isolates cultured from biopsies taken during routine endoscopies in 1998-1999. METHODS: Minimum Inhibitory Concentration of amoxicillin, tetracycline, clarithromycin and metronidazole were determined by Epsilometer test. RESULTS: Forty-seven strains (57%) were resistant to metronidazole, and 27 (32.5%) were resistant to clarithromycin. Twenty of the 27 strains resistant to clarithromycin were also resistant to metronidazole. None of the strains were resistant to amoxicillin or tetracycline. CONCLUSION: A high percentage of patients from Bahrain were infected with resistant strains of Helicobacter pylori. Antibiotic resistance monitoring is …

Gastrointestinal Strongyles In Wild Ruminants, Eric P. Hoberg, A. Alan Kocan, Lora G. Rickard

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Parasitologists have long studied helminth infections in wildlife species and have documented the existence of many organisms from a diversity of mammalian hosts. With this accumulation of information has come improved understanding of the significance of these organisms and the diseases they produce in their mammalian hosts. Some of the most notable examples include the metastrongyloid lungworms, Trichinella spiralis, and Elaeophora schneideri, which are covered separately in this volume. It is, however, for the group of parasites referred to as gastrointestinal nematodes that we have accumulated the most data. Only recently has progress been made in determining the …

Cyclospora, Eimeria, Isospora And Cryptosporidium Spp., Donald Duszynski, Steve J. Upton

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Coccidia are exceptionally common protist parasites of both vertebrates and, to a lesser extent, invertebrates. Every vertebrate species that ever has been examined intensively, over a broad geographic range, has been found to have at least one coccidian species unique to it and may have as many as five, ten, or more species. They also may have additional coccidia shared with close relatives (congenerics, sometimes confarnilials) and/or with sympatrics. The history of the development of our knowledge about coccidian parasites of wild mammals is long and tangled and has been reviewed by Levine, Joyner, and Long and Joyner. Suffice it …

Evaluation Of The Specificity Of Five Oligoprobes For Identification Of Cyathostomin Species From Horses, J. E. Hodgkinson, S. Love, J. Ralph Lichtenfels, S. Palfreman, Y. H. Ramsey, J. B. Matthews

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Here, we report evaluation of five oligoprobes designed from intergenic spacer (IGS) region sequences for identification of cyathostomin species. Oligoprobes were designed for identification of Cylicocyclus ashworthi, Cylicocyclus nassatus, Cylicostephanus longibursatus, Cylicostephanus goldi and a fifth probe designed to identify all members of this tribe. PCR amplification of IGS DNA from 16 cyathostomin species allowed sequence comparison and identification of four putative species-specific probes. Southern blotting of amplified products from 16 species showed that all probes were species-specific. The fifth probe recognised all 16 cyathostomin species but did not bind to members of the genus Strongylus. Furthermore, these probes …

Onchocercosis In Red Deer (Cervus Elaphus) From Spain, Mónica Santín-Durán, José M. Alunda, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Onchocercosis, caused by Onchocerca flexuosa, was observed in red deer (Cervus elaphus) from Spain for the first time. Adult specimens of O. flexuosa were found in nodules in subcutaneous tissues in 42 of 125 (33%) red deer between October 1994 and September 1995; intensity of infection 6 SD was 3.93 ± 5.26 nodules per infected host. A clear seasonal pattern in the distribution of nodules was observed, with higher values of prevalence and intensity in fall and winter in contrast to spring and summer. Significant differences were found among age groups in prevalence, but not in the …

Presentation Of The Asp Distinguished Service Award To Robert L. Rausch, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Over the past 50 years Robert Rausch has been at the forefront of research on the systematics, taxonomy, biogeography, epidemiology, and pathology of helminth parasites in vertebrate hosts. Research programs and projects have continually emphasized the complex interface of parasitology, sylvatic distributions of pathogens in wild mammals, and public health, whether dealing with tapeworms such as Echinococcus or Diphyllobothrium or with nematodes such as Trichinella. Most meticulous in research, contributions by Dr. Rausch have been characterized by their innovative nature, depth and scope of detail, complete articulation and examination of hypotheses, and novel insights integrating parasites and parasitism within …

Umingmakstrongylus Pallikuukensis (Nematoda: Protostrongylidae) In Gastropods: Larval Morphology, Morphometrics, And Development Rates, Susan J. Kutz, Eric P. Hoberg, Lydden Polley

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Morphological and morphometric aspects of larval development of Umingmakstrongylus pallikuukensis in Deroceras laeve and the effects of temperature on development rates in D. laeve and Deroceras reticulatum were investigated in the laboratory. Larval stages were best differentiated by separation of cuticular sheaths, tail structure, and viability following digestion. Growth in body and esophagus width was observed during the first-stage within the intermediate host, but the major increases in body length and width occurred immediately following the second molt. Larval development in D. laeve and D. reticulatum occurred more rapidly at warmer temperatures. The calculated threshold temperatures were 8.5 and 9.5 …

Worms, Nematoda, Scott Lyell Gardner

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Nematodes are the most speciose phylum of metazoa on earth. Not only do they occur in huge numbers as parasites of all known animal groups, but also they are found in the soils, as parasites of plants, and in large numbers in the most extreme environments, from the Antarctic dry valleys to the benthos of the ocean. They are extremely variable in their morphological characteristics, with each group showing morphological adapta­tions to the environment that they inhabit. Soil-dwelling forms are extremely small; many marine species have long and complex setae; and parasitic species man­ifest amazingly great reproductive potential and large …

Phylogenetic Position Of Eimeria Antrozoi, A Bat Coccidium (Apicomplexa: Eimeriidae) And Its Relationship To Morphologically Similar Eimeria Spp. From Bats And Rodents Based On Nuclear 18s And Plastid 23s Rdna Sequences, Xiaomin Zhao, Donald W. Duszynski, Eric S. Loker

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Partial plastid 23S and nuclear 18S rDNA genes were amplified and sequenced from 2 morphologically similar Eimeria species, E. antrozoi from a bat (Antrozous pallidus) and E. arizonensis from deer mice (Peromyscus spp.), as well as some other Eimeria species from bats and rodents. The phylogenetic trees clearly separated E. antrozoi from E. arizonensis. The phylogenies based on plastid 23S rDNA data and combined data of both plastid and nuclear genes grouped 2 bat Eimeria and 3 morphologically similar Eimeria species from rodents into 2 separate clades with high bootstrap support (100%, 3 rodent Eimeria species; …

Phylogenetic Analysis Of The Rhabdocoela (Platyhelminthes) With Emphasis On The Neodermata And Relatives, David Zamparo, Daniel R. Brooks, Deborah A. Mclennan, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Phylogenetic systematic analysis of 24 taxa representing the rhabdocoel platyhelminths, based on a suite of 89 morphological characters, produced two equally parsimonious trees, 181 steps long, with a consistency index (CI) of 0.69 and a rescaled consistency index (RCI) of 0.56, differing only with respect to that portion of the tree containing Umagillidae, Acholadidae, Graffillinae, Pseudograffillinae, Pterastericolidae and Hypoblepharinidae. Our results accommodate all previously proposed sister taxa to the Neodermata in a single clade in which ((Dalyelliidae + Temnocephalida) Typhloplanidae) is the sister group of ((Fecampiidae + Urastoma) (Udonella ((Aspidogastrea + Digenea) (Monogenea (Gyrocotylidea (Amphilinidea + Eucestoda)))))). Bootstrap …

Pfiesteria: Review Of The Science And Identification Of Research Gaps. Report For The National Center For Environmental Health, Centers For Disease Control And Prevention, Jonathan Samett, Gary S. Bignami, Robert Feldman, William Hawkins, Jerry Neff, Theodore Smayda

Graduate School of Oceanography Faculty Publications

In connection with the CDC National Conference on Pfiesteria, a multidisciplinary panel evaluated Pfiesteria-related research. The panel set out what was known and what was not known about adverse effects of the organism on estuarine ecology, fish, and human health; assessed the methods used in Pfiesteria research; and offered suggestions to address data gaps. The panel's expertise covered dinoflagellate ecology; fish pathology and toxicology; laboratory measurement of toxins, epidemiology, and neurology. The panel evaluated peer-reviewed and non-peer-reviewed literature available through June 2000 in a systematic conceptual framework that moved from the source of exposure, through exposure research and dose, …

Justice Or "Just Us"? Allocating Resources In An Age Of Aids, John F. Kilner

The Asbury Journal

No abstract provided.

Identification Of A Defensin From The Hemolymph Of The American Dog Tick, Dermacentor Variabilis, Robert Johns, Daniel E. Sonenshine, Wayne L. Hynes

Biological Sciences Faculty Publications

Hemolymph from partially fed virgin Dermacentor variabilis females was collected following Borrelia burgdorferi challenge and assayed for antimicrobial activity against Bacillus subtilis and B. burgdorferi. A small inducible cationic peptide was identified by SDS-PAGE in the hemolymph of these ticks as early as 1h post challenge. Following purification by a three-step procedure involving sequential SepPak elution, reversed phase high performance liquid chromatography (RP-HPLC) and gel electrophoresis, the yield of the active peptide was approximately 0.1% of the total protein in the hemolymph plasma. The molecular weight, 4.2kDa, was determined by MALDI-TOF mass spectrometry. N-terminal sequencing by the Edman degradation …

Tick Immunity To Microbial Infections: Control Of Representative Bacteria In The Hard Tick Dermacentor Variabilis (Acari: Ixodidae), Robert Johns, Shane Ceraul, Daniel E. Sonenshine, Wayne L. Hynes

Biological Sciences Faculty Publications

No abstract provided.

Prevalence Of Eimeria (Apicomplexa: Eimeriidae) In Reintroduced Gunnison's Prairie Dogs (Cynomys Gunnisoni), M. M. Ryan, K. H. Decker, Donald W. Duszynski

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Fecal samples from 54 Gunnison’s prairie dogs (Cynomys gunnisoni) from Albuquerque, NM were analyzed for the presence of coccidia and all were positive. They were then relocated to an abandoned prairie dog town on the Sevilleta Long Term Ecological Research (LTER) site. Six Eimeria species, E. callospermophili, E. cynomysis, E. pseudospermophili (new host record), E. spermophili, E. ludoviciani and E. vilasi (new host record) were found in Albuquerque animals, but only two species, E. callospermophili and E. vilasi were present in relocated hosts. A significant (P < 0.05) reduction was seen in the prevalence of E. vilasi (72% vs. 13%) and in the prevalence of infections …

Phylogey Of Steinernema Travassos, 1927 (Cephalobina: Steinnematidae) Inferred From Ribosomal Dna Sequences And Morphological Characters, S. Patricia Stock, James F. Campbell, Steven A. Nadler

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Entomopathogenic nematodes in Steinernema, together with their symbiont bacteria Xenorhabdus, are obligate and lethal parasites of insects that can provide effective biological control of some important lepidopteran, dipteran, and coleopteran pests of commercial crops. Phylogenetic relationships among 21 Steinernema species were estimated using 28S ribosomal DNA (rDNA) sequences and morphological characters. Sequences of the rDNA internal transcribed spacers were obtained to provide additional molecular characters to resolve relationships among Steinernema carpocapsae, Steinernema scapterisci, Steinernema siamkayai, and Steinernema monticolum. Four equally parsimonious trees resulted from combined analysis of 28S sequences and 22 morphological characters. Clades inferred from …

Excellence In Nursing Administration [Complete Issue: First Quarter 2001, Vol. 2, 1], Pamela Klauer Triolo, Paula Hansen, Ann Scanlon-Mcginity, Cynda Hylton Rushton, Kathleen Hartman Sabatier, Sigma Theta Tau International

Sigma Past Publishing - Excellence Newsletters

Publishing History: Nursing Excellence published yearly in 1998 and 1999. The publication became Excellence in the first quarter 2000. It transitioned to Excellence in Nursing Education, Excellence in Nursing Administration, and Excellence in Clinical Practice in the second quarter 2000 with volume 1, number 2. Excellence in Nursing Education transitioned to Excellence in Nursing Education & Research in the first quarter 2002.

Publishing Frequency: Yearly 1998, 1999; Quarterly 2000 - 2004.

Format: Print 1999 - third quarter 2002; Online fourth quarter 2002 - first quarter 2004. Ceased publishing in 2004.

Select features in this issue:

Back to basics: Retention of …

Risk Factors Associated With Acute Lower Respiratory Tract Infection In A Cohort Of Newborns From Birth To 24 Months Of Age In A Rural Community Of Bangladesh, Khundkar Zahid Hasan

All ETDs from UAB

Little is known about incidence, risk factors, and etiology of acute lower respiratory tract infection (ALRI) and pneumonia among the very young children from the rural communities of the developing countries. This study examined incidence and risk factors for ALRI and etiology and risk factors for pneumonia in a group of infants in Bangladesh. A cohort of 252 newborns was prospectively followed from birth to 24 months of age. Data on respiratory symptoms and feeding habits were collected routinely by household visit. Socioeconomic information was collected during census and during enrollment of the children. Laboratory tests for bacterial and viral …

A Multi-Dimensional Outcome Study Of Chronic Back Pain, Long-Term Characterization Of Three Treatments: Intrathecal Opioid Administration, Residential Pain Treatment Program, And Oral Opioid Therapy., Jessica Lynn Brown

All ETDs from UAB

No abstract provided.

Regulation Of Class Ii Transactivator And Class Ii Mhc Expression In Macrophages And Microglia., George Michael O'Keefe

All ETDs from UAB

No abstract provided.

Impact Of Social Support And Stress On Health-Related Quality Of Life Among People Living With Hiv And Aids., Hao Tang

All ETDs from UAB

No abstract provided.

Synthesis Of Phosphonopeptides And Alpha, Alpha-Dialkylated Amino Acid-Rich Peptides., Sheila Denise Rushing

LSU Historical Dissertations and Theses

Peptides and peptide analogs are central to the understanding of biological and biochemical phenomena as well as in the development of new pharmaceutical agents. This research encompasses two classes of peptide mimetics: phosphonopeptides and short, amphipathic peptides rich in alpha,alpha-disubstituted amino acids (alphaalphaAA). The focus of the first part of the peptide analog project was on the preparation of sterically-hindered phosphonamide and thiophosphonamide dipeptides. Conditions were developed, based on our P(III) synthetic approach, for the preparation of the phosphonamide dipeptides, Cbz-CyhGly psi [P (O) (OpNb) NH] Trp-NH2 and Cbz-CyhGly psi [P (O) (OpNb) NH] Trp-OMe, which were previously unattainable by …

Handling Cases Of Willful Exposure Through Hiv Partner Counseling And Referral Services, Lawrence O. Gostin, James G. Hodge Jr.

Georgetown Law Faculty Publications and Other Works

Cases of willful exposure reveal the existing and future risks to the public health (especially women) which may be presented by individuals who willfully expose others to HIV through unsafe sexual or needle-sharing behaviors. In response to a documented case of willful exposure, a PCRS counselor or other public health official may, in his or her professional judgment, decide to act to avert a legitimate public health threat to known or unknown persons in the community. Yet handling such cases raises difficult issues in law, ethics, and public health practice. Public health authorities may be unable or ill-equipped to successfully …