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Effects Of Acute Grayanotoxin-I Administrationon Hepatic And Renal Functions In Rats, Meral Aşçioğlu, Çi̇ğdem Özesmi̇, Paki̇ze Doğan, Fi̇ngen Öztürk

Turkish Journal of Medical Sciences

The effects of acute Grayanotoxin-I (GTX-I) administration on hepatic and renal functions in rats were investigated. GTX-I was administrated to the animals of groups 1, 2 and 3 at a single i.p. dose of 1 mg/kg, 0.5 mg/kg and 0.25 mg/kg respectively, and group 4 (control) received i.p. saline (0.9 %) solution only. One hour following the administration of GTX-I or saline, urine analysis (leukocytes, urobilinogen, protein, pH, blood, ketone, glucose, nitrites) was performed and serum was evaluated for activities of glutamic pyruvic transaminase (GPT), \gamma-glutamyl transferase (\gamma-GT) and isoenzymes of lactate dehydrogenase (LDH) (as a percentage of total LDH …

The Effect Of Iron Bound Transferrin Onmegakaryocytopoiesis In Bone Marrow Culture, Selda Deli̇orman, Ruhi̇ Uyar, Yilmaz Altuner

Turkish Journal of Medical Sciences

Megakaryocytopoiesis is a complicated phenomenon which involves the proliferation of progenitor cells, formation of a polyploid nucleus, cytoplasmic changes and formation of thrombocytes. It has been suggested that megakaryocytopoiesis resembles erythropoiesis. It is well known that iron is a required element for the proliferation of erythrocytes, lymphocytes and cancer cells but no consensus has yet been reached about its role in thrombocytopoiesis. Although thrombocytosis is generally found in patients with iron deficiency anemia, thrombocytopenia is also observed. Cell surface receptors for transferrin were initially characterized on cells with high iron requirements including hemoglobin producing cells and placental cells. More recently, …

Determinants Of Birth Weight: Does Air Pollutionhave An Influential Effect?, Selda Hizel, Turgay Coşkun

Turkish Journal of Medical Sciences

To investigate the influence of air pollution on birth weight, information on maternal and infant characteristics was collected from 458 mothers of infants less than one year of age born in 1995 and under observation at a mother and child health center in Ankara. In addition, the obstetrical histories of 520 infants born in 1990 were collected from the delivery room records of a maternity hospital. Daily air pollution data were obtained and mean monthly values were used for statistical analysis. Among the possible risk factors, sex, maternal age, maternal employment, paternal employment and parity were found to be influential …

Hydatid Disease Of The Liver: Spontaneousrupture Of The Portal Vein Into The Cyst Wall (Arare Complication), Nusret Akyürek, Erdal Kayhan, Mustafa Kerek

Turkish Journal of Medical Sciences

No abstract provided.

Preparation Of Bovine Serum Albuminmicrospheres Containing Dexamethasone Sodiumphosphate And The In Vitro Evaluation, Hakan Eroğlu, H. Süheyla Kaş, Levent Öner, Mustafa Sargon, A. Ati̇lla Hincal

Turkish Journal of Medical Sciences

Dexamethasone sodium phosphate (DSP) is the most common corticosteroid used in the treatment of edema paired with brain tumors (1, 2). As with other corticosteroids, DSP has some adverse effects on the cardiovascular, immune and nervous systems. The objective of this study was to minimize the adverse effects of DSP and to extend the release time of the drug from microspheres by encapsulating with Bovine Serum Albumin (BSA). The microspheres were prepared by emulsion polymerization. An aqueous solution of glutaraldehyde (25% w/v) was used as the crosslinking agent in two different amounts. The release time DSP was found to be …

Obesity And The Activity Of The Autonomicnervous System, Rami̇s Çolak, Emi̇r Dönder, Azi̇z Karaoğlu, Oğuz Ayhan, Mehmet Yalniz

Turkish Journal of Medical Sciences

This study was conducted to examine the autonomic nervous system functions of obese people. The study group consisted of 30 healthy obese people (20 female, 10 male, age range 18-58, median 37.6±9.7 years of age) and the control group consisted of 30 healthy nonobese people (18 female, 12 male, age range 17- 56, median 34.4±7.5 years). Each function was tested by non-invasive applications (orthostatic test, isometric exercise test, Valsalva ratio test, 30/15 ratio test, heart rate change test by deep respiration). The results of the orthostatic test and isometric- exercise test yielded a statistically significant difference between the study and …

Isoniazid Poisoning With Seizures, Shoulderdislocation, And Fracture Of The Greatertuberosity, Yüksel Gökel, Sali̇m Satar, Mehmet Duru, Zi̇kret Köseoğlu, Güven Kuvandik

Turkish Journal of Medical Sciences

No abstract provided.

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Effects Of Growth Hormone On Bacterial Translocation Due To Intestinal Obstruction, Ahmet A. Balik, M. İlhan Yildirgan, Ali̇ Kiliç, Cemal Gündoğdu, Fazli Erdoğan

Turkish Journal of Medical Sciences

Bacterial translocation is an important etiologic factor in multisystem organ failure and sepsis, which have a high mortality rate. To determine the effects of growth hormone on bacterial translocation, an experimental study was performed. Twenty pathogen-free rabbits were divided into two groups each containing 10 rabbits. After loop obstruction was performed, the rabbits in the control group were given saline solution whereas the rabbits in the study group received growth hormone. Relaparotomy was performed after 24 hours, and tissue and blood samples were collected for histopathologic and microbiologic examinations. Bacterial translocation rates were higher in the control group than in …

Nimodipine Aggravates Systemic Kainic Acid Toxicity In Retinal Ganglion Cells Of Intact Mice, Akçahan Gepdi̇remen, Murat Kaya, İbrahi̇m Koçer, Cemal Gündoğdu

Turkish Journal of Medical Sciences

The aim of the present study was to investigate the role of the L-type voltage dependent Ca^2^+ channel blocker, nimodipine, in kainate induced toxicity in retinal ganglion cells of mice. Kainate in 10mg/kg was administered intraperitoneally following the vehicle or nimodipine. Nimodipine, 45 minutes prior to kainate in 10, 15, 25, 50, 100 and 250 mg/kg doses was administered intraperitoneally. Surprisingly, nimodipine potentiated the ganglional cell death induced by kainate, with respect to the control and kainate+vehicle treated group. In accordance with our results, blockage of L-type calcium channels by nimodipine may worsen the prognosis and survival of retinal neurons …

Biomimetic Preparation Of Ha Powders At 37°C In Urea-And Enzyme Urease-Containing Synthetic Body Fluids, Defne Bayraktar, A. Cüneyt Taş

Turkish Journal of Medical Sciences

An important inorganic phase of synthetic bone applications, calcium hydroxyapatite (HA, Ca_10 (PO_ 4 ) 6_(OH_2 ), was prepared as a single-phase and sub-micron bioceramic powder. Carbonated HA powders were synthesized from calcium nitrate tetrahydrate and di-ammonium hydrogen phosphate salts dissolved in synthetic body fluid (SBF) solutions, containing urea (H_2 NCONH_2 ) and enzyme urease, under the biomimetic conditions of 37°C and pH 7.4, with a novel chemical precipitation technique. These powders were also found to contain trace amounts of Na and Mg ions in them, intentionally incorporated by using SBF solutions, instead of pure water, during their synthesis. The …

The Role Of Immunological Factors In Wound Infections (A Prospective Clinical Study), Nusret Akyürek, Mustafa Kerek, Osman Yüksel, Türkan Patiroğlu

Turkish Journal of Medical Sciences

Wound infections are among the major problems complicating surgical procedures. The aim of this study was to investigate the relationship between the immunological status of the patient and wound infections. Wounds were classified as clean, clean-contaminated, contaminated and dirty. T-lymphocyte(CD3+), B-lymphocyte (CD19+) and total lymphocyte(CD45+) counts, and IgG, IgM, IgA levels were measured at the beginning of treatment, and on the fifth and tenth days. The levels of CD3+, CD19+, CD45+, IgGM, IgA were not different in the groups, while in the dirty group, IgG levels were lower than in the other groups, at the beginning of treatment (P0.05). There …

Decreased Placental Adrenomedullin May Play Role In Preeclampsia, Remzi̇ Gökdeni̇z, Muhi̇tti̇n Yürekli̇, Alanur Menekşe, Nursel Bazoğlu

Turkish Journal of Medical Sciences

Adrenomedullin (AdM) is a novel peptide that elicits a long-lasting vasorelaxant activity. It is expressed in several tissues, including adrenal medulla, heart, lung, kidneys, and cultured vascular smooth muscle cells. Also in large amounts, it is present in amniotic fluid and cord blood. The aim of this study was to assess placental AdM secretion in preeclampsia. Placental tissues were collected from seven preeclamptic patients and ten healthy gravidas. Tissue concentration of rat AdM was measured by using reverse-phase high performance liquid chromatography (Cecil 1100). Mann Whitney U test was used for statistical significance. Significance was set at p

Prevalence Of Goitre And Its Relationship With Iodine Deficiency In School Children In Kocaeli, Turkey, Şükrü Hatun, Sidika Beykal, Yenal Dündar, Olcay Evli̇yaoğlu

Turkish Journal of Medical Sciences

Prevalence of Goitre and Its Relationship with Iodine Deficiency in School Children in Kocaeli, Turkey 5564 primary school children living in Kocaeli, Turkey, were clinically assessed for thyroid gland enlargement. Goitre was graded according to the WHO 1994 classification. 792 children showed various grades of goitre, giving a prevalence of overall goitre of 14.23%. The median urinary iodine values were found to be greater than 10mg/dl in each group of 20 students, who were selected randomly from those in whom Grade I and Grade II goitre had been detected and from those in whom goitre had not been detected. These …

Serum Antiotensin Converting Enzyme Activity In Streptozotocin-Induced Diabetic Rats, Mustafa Vakur Bor, Esra Seval Elmali, Ni̇lgün Altan

Turkish Journal of Medical Sciences

No abstract provided.

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Student Withdrawal: Test Of An Integrated Model, Gary A. Adams, Ron Marks, Jeff Allen

Management Faculty Research and Publications

This study examined a model of student withdrawal that integrated the major elements of Tinto's (1975) Student Integration Model and Bean's (1982, 1983) Industrial Model of Student Attrition. In a sample of 315 college freshman, the results of a path analysis indicated that both social and academic integration were related to satisfaction but only academic integration was related to commitment. Neither social nor academic integration had significant direct effects on intention to withdraw. Further, of the two attitudinal variables, satisfaction was related to intention to withdraw, however, commitment was not. These findings support the integrated model of student withdrawal.

Bringing Acquisition Reform Into Focus, Steve G. Green, David R. King, Neal J. Rappaport

Management Faculty Research and Publications

The response of our defense industrial base to major changes, such as the collapse of the former Soviet Union, emphasize the need to continue to improve the way the United States buys weapon systems. By looking through a historical lens, this paper addresses predicting the long-term success of acquisition practices and reform initiatives for the cost community. A literature review identifies acquisition reform legislation and initiatives since World War II. Looking at past acquisition reform and their long term impacts leads to the conclusion that acquisition reform efforts must be viewed skeptically. Given a dynamic environment, estimating costs may actually …

Data Mining In Health-Care: Issues And A Research Agenda, Monica Adya

Management Faculty Research and Publications

While data mining has become a much-lauded tool in business and related fields, its role in the healthcare arena is still being explored. Currently, most applications of data mining in healthcare can be categorized into two areas: decision support for clinical practice, and policy planning/decision making. However, it is challenging to find empirical literature in this area since a substantial amount of existing work in data mining for health care is conceptual in nature. In this paper, we review the challenges that limit the progress made in this area and present considerations for the future of data mining in healthcare.

The Distributed User Modeling Shell System (Dumss): A Conceptual Framework For Eliciting User Models, Thawatchai Piyawat, Monica Adya, Anthony F. Norcio

Management Faculty Research and Publications

With the advances in communication technology, large volumes of information can transfer across continents within a fraction of a second. Nevertheless, computer users still suffer from unpleasant situations when they interact with systems and are required to adapt to systems rather than the other way round. User modeling aims to overcome this problem by enabling computer systems to interact with users according to the users’ models, i.e., goals, knowledge, and preferences of users. Although, user modeling has shown invaluable benefits, methods of capturing user information to build precise and useful user models are still in their early states. This paper …

An Analysis Of Using Expert Systems And Intelligent Agents For The Virtual Library Project At The Naval Surface Warfare Center-Carderock Division, J. Liebowitz, Monica Adya

Management Faculty Research and Publications

The Virtual Library Project1 at the Naval Surface Warfare Center/Carderock Division (NSWC/CD) is being developed to facilitate the incorporation and use of library documents via the Internet. These documents typically relate to the design and manufacture of ships for the U.S. Navy Fleet. As such, the libraries will store documents that contain not only text but also images, graphs and design configurations. Because of the dynamic nature of digital documents, particularly those related to design, rapid and effective cataloging of these documents becomes challenging. We conducted a research study to analyze the use of expert systems and intelligent agents to …

Contract As Commodity: A Nonfiction Approach, John J.A. Burke

Seton Hall Journal of Legislation and Public Policy

No abstract provided.

2000-2002 Bulletin, Benjamin N. Cardozo School Of Law

Cardozo Law Bulletin

Contents:

Legal Studies at Cardozo, p. 8

Degree Requirements, p. 12

Courses, p. 14

The Lawyering Curriculum, p. 23

Faculty, p. 36

Student Resources, p. 48

Dr. Lillian and Dr. Rebecca Chutick Law Library, p. 49

The Center for Professional Development, p. 50

Public Interest Opportunities, p. 52

Employment, p. 54

Student Life, p. 56

Admissions, p. 63

Tuition & Student Finances, p. 63

Cardozo Administration and Board of Directors, p. 67

Academic Calendar, p. 72

2000 Cardozo School Of Law, Benjamin N. Cardozo School Of Law

Yearbooks

No abstract provided.

Did Bacillus Megaterium Pick Up Plasmid Virulence Genes?, Sharin M. Gabl

Honors Capstones

Plasmids are known to carry genes that allow bacteria to survive in different environments. Virulence genes that cause bacteria to be pathogenic are also found on plasmids. Bacillus megaterium is a non-pathogenic, spore-forming bacteria that is found in soil, but recently a strain of B. megaterium was reported to cause a mild case of diarrhea in an infant. This appears to be the first case of infection caused by B. megaterium (CHI). Bacillus cereus is a related species and a known gastroenteric pathogen. Research has shown that the pathogenicity in some strains of B. cereus is caused by either an …

Dejavue, Inc., A Utah Corporation, Kristine C. Shultz, And Allison Nord V. U.S. Energy Corp., A Wyoming Corporation : Brief In Opposition To Certiorari, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

APPEAL FROM THE FINAL JUDGMENT OF THE THIRD JUDICIAL DISTRICT COURT FOR SALT LAKE COUNTY (HONORABLE HOMER F. WILKINSON)

Skyline Leasing V. Datacap, A Division Of International Computer Systems, Inc., A Utah Corporation; And International Computer Systems, Inc., A Utah Corporation : Brief Of Respondent, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

No abstract provided.

Crestview-Holladay Home Owners Association, Inc. V. Engh Floral Co., Salt Lake County : Petition For Rehearing, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

Appeal from a Judgment of the Third Judicial District Court of Salt Lake County Honorable Gordon R. Hall, judge

Sterling B. Cannon, George H. Maxwell, Dave Davis, Art Van Luyx, And Terry Teeples V. Stevens Schools Of Business, Inc. : Petition For Rehearing, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

Appeal from a Judgment of the District Court of Salt Lake County Honorable Stewart M. Hanson, Sr., Judge

Effects Of Foot Orthoses On Skeletal Motion During Running, A. Stacoff, C. Reinschmidt, B. M. Nigg, Antonie J. Van Den Bogert, A. Lundberg, J. Denoth, E. Stüssi

Mechanical Engineering Faculty Publications

Objective. To quantify the effects of medial foot orthoses on skeletal movements of the calcaneus and tibia during the stance phase in running.

Design. Kinematic effects of medial foot orthoses (anterior, posterior, no support) were tested using skeletal (and shoe) markers at the calcaneus and tibia.

Background. Previous studies using shoe and skin markers concluded that medially placed orthoses control/reduce foot eversion and tibial rotation. However, it is currently unknown if such orthoses also affect skeletal motion at the lower extremities.

Methods. Intracortical Hofman pins with reflective marker triads were inserted under standard local anesthetic into the calcaneus …