Digital Commons Network^™

Interactions Of Igf-Ii And Cathepsin D In Mcf-7 Breast Cancer Cells, Jesika S. Faridi

Loma Linda University Electronic Theses, Dissertations & Projects

A primary role of the IGF-II/M6P receptor is to target lysosomal enzymes from the golgi to the lysosomes. This receptor has distinct binding sites for IGF-II and M6P, however, reciprocal interactions between these ligands have been observed (Kiess et al. 1989, 1990). Since IGF-II modulates the routing of cathepsin D in MCF-7 cells by blocking the intracellular binding of cathepsin D to the IGF-II/M6P receptor (De León et al. 1996), we hypothesized that expressing a mutant form of IGF-II that does not bind the IGF-II/M6P receptor will not interfere with lysosomal enzyme trafficking.

In our present study, we report the …

Connexin-32 Contributes To Radiation Resistance In Thyroid Follicles, Da-Thao Dinh Tran

Loma Linda University Electronic Theses, Dissertations & Projects

The objective of this study was to examine the role of gap junctions in the radiation resistance of thyroid follicles. The question of whether gap junctional intercellular communication plays an important role in the “contact effect”, wherein cells in direct apposition are more resistant to the damaging effects of radiation, has been debated for years. We used the Fischer rat thyroid cell line (FRTL-5) to carry out our experiments. This thesis is divided into two parts: 1) characterization of gap junctional properties in FRTL-5 cells and, 2) exposure of these cells to radiation.

We found that, unlike primary thyroid cells, …

Lady Griz Basketball Media Guide, 2000-2001, University Of Montana--Missoula. Athletics Department

Lady Griz Basketball Media Guides, 1978-2009

Media guide created about the Lady Griz basketball team.

Que Ondee Sola - September 2000, Michael Rodriguez-Muniz

Que Ondee Sola

Student publication founded in 1972, articles include: Vieques Needs You Now, Hidalgo's Call for Mexican Independence, The Role of Education, Seven Loose Pieces of the Global Jigsaw Puzzle Part 2, A Year Ago 11 of Our Patriots Were Released, A Short Biography of Pedro Albizu Campos, Desde la Cocina, Denied Appeal, The Future of the Mexican/Caribbean Studies Minor, Latino Roots in Hip Hop, Poetry

Mandatory Disclosure: A Controversial Device With No Effects, Kuo-Chang Huang

Pace Law Review

No abstract provided.

Molecular Cloning And Analysis Of The Modification Genes Of The Kpnbl Restriction- Modification System Of Klebsiella Pneumoniae Strain Gm236, Vernon Robert Chin

Loma Linda University Electronic Theses, Dissertations & Projects

The KpnBl restriction-modification (R-M) system has been recognized for some time in Klebsiella pneumoniae strain GM236. Previously the restriction subunit (hsdR_kpmBI) was cloned and sequenced, based on the sequence infonnation the KpnBl RM system was suspected to be either a type I or type III R-M system In this project the modification genes of KpnBl were cloned into a pMECA plasmid by using a modification expression method. The modification genes were identified on an 8.2 kb EcoRl fragment from a chromosomal library of the GM236 strain. The complete 8.2 kb fragment was sequenced and …

A Study Of The Effects Of Strain On Niti Shape Memory Alloy, Bret Oltmans

Theses

Shape memory alloys are materials that are capable of returning to an original shape after large deformations in response to a stimulus. Shape memory alloys can be metals, ceramics, polymers and gels. This thesis studies the changes of various properties of NiTi metal as samples are prestrained various amounts. After conducting various characterization techniques, relationships were developed for the changes in transformation temperatures, Knoop hardness number, and crystal lattice parameters. Through the use of differential scanning calorimetry and dynamic mechanical analysis the transformation temperatures were determined. It was observed in both experiments that the initial austenite start temperature(As) increased parabolically …

Portland State Magazine, Portland State University. Office Of University Communications

Portland State Magazine

PSU’s alumni magazine, published 2-3 times a year. In this issue: Faculty engage in the ethical debate surrounding genetic privacy; the football team makes Hillsboro its home away from home; photos and stories shed light on the history of Portland’s YWCA; after 35 years, the artist who painted the mural in Smith Center has returned to campus; an economic professor’s fiery invention could help people in the Third World; and more.

2nd Meeting Of The States Parties To The Anti-Personnel Mine Ban Convention (2000), Apmbc

Global CWD Repository

Geneva, 11-15 September 2000

SECOND MEETING OF THE STATES PARTIES TO THE CONVENTION ON THE PROHIBITION OF THE USE, STOCKPILING, PRODUCTION AND TRANSFER OF ANTI-PERSONNEL MINES AND ON THEIR DESTRUCTION

Dotcoms: Evolution Or Revolution?, Rishikesha T Krishnan, D Sampath

IIMB Management Review

The young dotcom turks, consultants, venture capitalist academic experts, HR, and media professionals who debated on the dotcom phenomenon were Ravi Anshuman. Assistant Professor; Finance & Control, IIMB; Akhil Awasthi, Vice President, Baring Private Equity Partners; Jagadish N Bapat, Director HR, LG Soft India; Simon Bell, Principal, and Rahul Chadha, A T Kearney; Somnath Chowdhury, Editor; IT Space.com; Ajith Isaac, CEO, go4careers .com; Praveen Kanipakkam, President, Sharp Software; Nitin Karve, Partner in-Charge, KPMG, Bangalore; Arun Korati, Associate Vice President and Deepa Sankaran, Manager~ IL & FS Venture Corporation.; V S Sudhakar; CEO, FABMART; Dvvijendra Tripathi, business historian and former Professor …

Section 8: Looking Ahead: Upcoming Issues In The Court, Institute Of Bill Of Rights Law, William & Mary Law School

Supreme Court Preview

No abstract provided.

Section 7: Federalism, Institute Of Bill Of Rights Law, William & Mary Law School

Supreme Court Preview

No abstract provided.

2000-2001 Supreme Court Preview: Contents, Institute Of Bill Of Rights Law, William & Mary Law School

Supreme Court Preview

No abstract provided.

The Murray State News, September 1, 2000, The Murray State News

Murray State University Collection

No abstract provided.

Washington University Record, September 1, 2000

Washington University Record

No abstract provided.

Nobel Laureate 2000 Gao Xingjian And His Novel Soul Mountain, Mabel Lee

CLCWeb: Comparative Literature and Culture

In her article, "Nobel Laureate 2000 Gao Xingjian and his Novel Soul Mountain," Mabel Lee introduces Gao Xingjian, the winner of the Nobel Prize in Literature of 2000. Lee is the translator of several of Gao's works from the Chinese into English, including the Nobel's main text of reference, Soul Mountain (first published in Chinese in 1990). Lee's article combines descriptions of Gao's biographical background and its relevance to his work and writing with a brief analysis of literary aspects of Gao's work based on tenets of the comparative literary and cultural studies approach. As is evident in Gao's texts, …

The Hazard Of Hidden Interactions: A Reanalysis Of Designs In Reaction-Time Studies On Metaphor, Johan F. Hoorn

CLCWeb: Comparative Literature and Culture

In his article, "The Hazard of Hidden Interactions: A Reanalysis of Designs in Reaction-Time Studies on Metaphor," Johan F. Hoorn argues that research designs in empirical literature and the psychology of aesthetics often include unanalyzed factors. The nature of these factors may be linguistic such as word frequency or lexical ambiguity or technical such as presentation order, repeated measures, etc. By not correctly analyzing an experiment, higher-order interactions may go unnoticed, while interfering with results. Hoorn reviews a sample of reaction-time experiments on metaphors, some of which are considered key studies in the area. Because the quality of an argument …

Peaches, Speech, And Clarence Thomas: Yes, California, There Is A Justice Who Understands The Ramifications Of Controlling Commercial Speech, Jennifer R. Franklin

Faculty Publications

No abstract provided.

Undergraduate Catalog, Fall 2000, New Jersey Institute Of Technology, New Jersey Institute Of Technology

Course Catalogs

No abstract provided.

American Strategy: Issues And Alternatives For The Quadrennial Defense Review, Steven Metz Dr.

Books, Monographs & Collaborative Studies

The combination of a congressionally-mandated Quadrennial Defense Review (QDR), a change of presidents, and shifts in the global security environment will force or allow American strategists to rethink some of the basic elements of U.S. strategy and decide if any changes need to be made. It is vital that the defense transformation process be strategy driven rather than dictated by budgets or technology alone. In other words, the first step in assessing the status and the future of American strategy is to examine the concepts and broad alternatives on which it is built.

In this monograph, the author begins with …

Isolation Of Moraxella Catarrhalis In Patients At King Khalid University Hospital, Riyadh, Hanan A. Babay

Saudi Medical Journal

OBJECTIVE: A retrospective study was carried out to assess the clinical significance of Moraxella catarrhalis (M. catarrhalis) isolated from 32 specimens received from patients seen during a 2 year period. METHODS: The identity of isolates was confirmed by DNAse production and reduction of nitrate to nitrite. Susceptibility testing and B-lactamase production was carried out for each isolate. RESULTS: Twenty three of the patients were adults and 9 were children. Twelve (37%) of the isolates were from the sputum of patients aged more than 50 years with a clinical diagnosis of pneumonia, bronchitis or bronchiactesis. Six (18%) had M. catarrhalis isolated …

The Pattern Of Hearing Impairment Among Schoolboys In An Institute For Deaf Subjects, Mostafa A. Abolfotouh, Saeed A. Al-Ghamdi

Saudi Medical Journal

OBJECTIVE: The aim of this study was to study the pattern of deafness among boys of Al-Amal Institutes for the Deaf in Abha, the capital city of Asir Region, Southwestern Saudi Arabia. METHODS: All students (n=155) were subjected to full otoscopic and audiometric examinations, and the type and degree of deafness were graded according to the recommendation of the British Society of Audiology. Computerized tomography scan was carried out to exclude congenital inner ear deformity, and specific Igm antibodies assay for TORCHS was carried out when the history of intrauterine infection was positive or suggestive. RESULTS: More than 97% of …

Articles/Essays, North Carolina Law Review

North Carolina Law Review

No abstract provided.

Subjects, North Carolina Law Review

North Carolina Law Review

No abstract provided.

Chimes: September 1, 2000, Calvin College

Chimes

It started with just one student ... by Nathan Bierma

Online buying can save on books by Nathan VanderKlippe

Do you like to watch? by Mark Deroo

Hearing the music, seeing the bands by Mark Deroo

Room for everyone in clubs by Nathan VanderKlippe

What's to love? by Mariann Olson

Computing Optimal Pumping Strategies For Groundwater Contaminant Plume Remediation, Richard C. Peralta, Alaa H. Aly

Civil and Environmental Engineering Faculty Publications

Simulation/Optimization (S/0) models can greatly simplify the process of designing remediation systems for contaminated groundwater. We describe some technical aspects of using S/0 models and possible S/0 model formulations for groundwater remediation design. We: discuss some S/0 model optimization algorithms; illustrate simple optimization problem solution; describe two real-world S/0 model applications; and demonstrate S/0 model application under uncertainty.

Machoism And The Rape Epidemic In South Africa, Shima Baradaran

Sigma: Journal of Political and International Studies

No abstract provided.

The Development Of Religious Liberty In Chile, 1973-2000, Patrick J. Thurston

BYU Law Review

No abstract provided.

Applying A Gender Perspective In The Area Of The Right To Freedom Of Religion Or Belief, Bahia Tahzib-Lie

BYU Law Review

No abstract provided.

The Nature And Minimum Standards Of Freedom Of Religion Or Belief, Natan Lerner

BYU Law Review

No abstract provided.