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Articles 6661 - 6690 of 2260534
Full-Text Articles in Entire DC Network
Perez V. Meisner
All Decisions
In this HP proceeding, a default order and money judgment had been entered against Respondent-owners before they appeared by counsel. The court vacated the default judgment, finding Respondent-owners presented a reasonable excuse for their non-appearance and a meritorious defense. The court reaffirmed the April 2025 order to correct and allowed Respondent-owners to file a late answer.
Reducing Communicable-Disease Risk After Earthquakes: Vaccination And Prevention Lessons For Venezuela's Doublet, Alfonso J Rodriguez-Morales, Ivan Arturo Rodríguez-Sabogal, Adriana Sucari, Wendy Moncada, Lili Vanessa Hernández-Serrano, Florencia Escarrá, Pasesa Pascuala Quispe-Torrez, Francisco Javier Membrillo, Tomás Orduna, Susana Lloveras, Tânia S S Chaves, Miguel M Cabada, Cecilia Perret, René Echavarría, Ana F Ribeiro, Melinda Tanabe, Fernando Bazzino, Maximiliano Ramirez, Baruch Diaz, Karen Mirna Loro Morejón, Karen Daly, Reinaldo Rosas, Maria Belen Lopez, Cristina Miranda, Marisa Liliana Fernandez, Yasemin Özsürekçi, Wasin Matsee, Yenddy Carrero, Cristian Biscayart, Sergio Cimerman, Maria L Avila-Aguero, Roberto Debbag, Jose Brea, Alejandro Risquez, Jaime David Acosta-España, Rolando Ulloa-Gutierrez, Carlos Espinal, Carlos N Torres-Martinez, Marta González-Sanz, Aula Abbara, Jill Weatherhead, Bernal Cordero, Virgilio Lezcano, Amanda Guerrero, Herberth Maldonado, Luis Cuellar, Ines Ceron, Yori Roque, Melisa Florentin, Rosa Infante, Ana Carvajal, Lily M Soto-Ávila, Marbelys Hernández, Hector Villaroel, Gianmary Miozzi, Rafael Navas, Moraima Hernández, Carlos Pérez-Vega, Manuela Mérida, David A Forero-Peña, Juan-Carlos Navarro, Claudia Beltrán-Arroyave, Mario Masana
Reducing Communicable-Disease Risk After Earthquakes: Vaccination And Prevention Lessons For Venezuela's Doublet, Alfonso J Rodriguez-Morales, Ivan Arturo Rodríguez-Sabogal, Adriana Sucari, Wendy Moncada, Lili Vanessa Hernández-Serrano, Florencia Escarrá, Pasesa Pascuala Quispe-Torrez, Francisco Javier Membrillo, Tomás Orduna, Susana Lloveras, Tânia S S Chaves, Miguel M Cabada, Cecilia Perret, René Echavarría, Ana F Ribeiro, Melinda Tanabe, Fernando Bazzino, Maximiliano Ramirez, Baruch Diaz, Karen Mirna Loro Morejón, Karen Daly, Reinaldo Rosas, Maria Belen Lopez, Cristina Miranda, Marisa Liliana Fernandez, Yasemin Özsürekçi, Wasin Matsee, Yenddy Carrero, Cristian Biscayart, Sergio Cimerman, Maria L Avila-Aguero, Roberto Debbag, Jose Brea, Alejandro Risquez, Jaime David Acosta-España, Rolando Ulloa-Gutierrez, Carlos Espinal, Carlos N Torres-Martinez, Marta González-Sanz, Aula Abbara, Jill Weatherhead, Bernal Cordero, Virgilio Lezcano, Amanda Guerrero, Herberth Maldonado, Luis Cuellar, Ines Ceron, Yori Roque, Melisa Florentin, Rosa Infante, Ana Carvajal, Lily M Soto-Ávila, Marbelys Hernández, Hector Villaroel, Gianmary Miozzi, Rafael Navas, Moraima Hernández, Carlos Pérez-Vega, Manuela Mérida, David A Forero-Peña, Juan-Carlos Navarro, Claudia Beltrán-Arroyave, Mario Masana
Faculty, Staff and Students Publications
No abstract provided.
High-Order Brain Interactions During Ketamine-Induced State Changes: A Functional Marker Of Response In Late-Life Treatment-Resistant Depression?, Krisha Shah, Rubén Herzog, Alan C Swann, Brittany O'Brien, Rahul Balakrishnan, Sanjay J Mathew, Nicholas Murphy
High-Order Brain Interactions During Ketamine-Induced State Changes: A Functional Marker Of Response In Late-Life Treatment-Resistant Depression?, Krisha Shah, Rubén Herzog, Alan C Swann, Brittany O'Brien, Rahul Balakrishnan, Sanjay J Mathew, Nicholas Murphy
Faculty, Staff and Students Publications
Ketamine is a fast-acting intervention for treatment-resistant depression (TRD), yet only a subset of patients show robust clinical response, and the underlying neural mechanisms remain unclear. High-order interactions (HOI) derived from multivariate information theory provide a framework for examining nonlinear dependencies among brain regions beyond pairwise connectivity. One such metric, the O-information, captures the balance between synergistic and redundant interactions across three or more variables. In this secondary analysis of a randomized, double-blind, midazolam-controlled trial (NCT02556606), we examined EEG-derived HOI in 30 late-life veterans with TRD following a single 40-minute intravenous infusion of ketamine (0.1, 0.25, 0.5 mg/kg; n = …
The Coupled Hydrology–Human Activity Information (Chhai) Dataset: A Global Benchmark Dataset For Model Comparison And Evaluation, Azara Boschee, Aneseh Alborzi, Augustina Clara Alexander, Berit Arheimer, Salsebil Bel Hadj Ali, Günter Blöschl, Andrea Castelletti, Xi Chen, Aniya Dogra, Erhu Du, Jesse Duku, Aldo Fiori, Margaret Garcia, Salvatore Grimaldi, Naota Hanasaki, Yeonjoo Kim, Heidi Kreibich, Chenyuan Li, Ali Mehran, For Full Author List, See Comments Below
The Coupled Hydrology–Human Activity Information (Chhai) Dataset: A Global Benchmark Dataset For Model Comparison And Evaluation, Azara Boschee, Aneseh Alborzi, Augustina Clara Alexander, Berit Arheimer, Salsebil Bel Hadj Ali, Günter Blöschl, Andrea Castelletti, Xi Chen, Aniya Dogra, Erhu Du, Jesse Duku, Aldo Fiori, Margaret Garcia, Salvatore Grimaldi, Naota Hanasaki, Yeonjoo Kim, Heidi Kreibich, Chenyuan Li, Ali Mehran, For Full Author List, See Comments Below
Faculty Research, Scholarly, and Creative Activity
To enhance hydrologic modeling, the hydrology community has developed benchmark datasets (e.g. Model Parameter Estimation Experiment, MOPEX), providing standardized data for model evaluation and parameter estimation. However, these datasets primarily focus on modeling natural hydrologic processes, leaving a critical gap in understanding the role of human influences. Here, we introduce the Coupled Hydrology-Human Activity Information (CHHAI) dataset, a benchmark dataset that integrates coupled human–water data from regions across all continents, excluding Antarctica. CHHAI incorporates data from 25 regions that cover various human impacts such as reservoir management, flood protection, river management policies, land use changes, and water use. Each basin …
Research Competence, Technology Skills As Correlates For Job Satisfaction Among Librarians In Universities In Delta State, Oghuvbu Blessing
Research Competence, Technology Skills As Correlates For Job Satisfaction Among Librarians In Universities In Delta State, Oghuvbu Blessing
Library Philosophy and Practice (e-journal)
Librarians perform academic and professional functions in universities, which require them to have job satisfaction for effective job performance. This study worked at the intersection of research competencies, technological skills and job satisfaction among librarians in universities in Delta State, Nigeria. The population of the study was the entire 81 librarians in universities in the state. A total population sampling was adopted. Data collected using a structured questionnaire was analysed using mean and standard deviation. The study found a high level of research competence, technology skills, and job satisfaction among the librarians in the universities. Conclusion the study found that …
Efficient Dynamic Mechanism Design Without A Common Prior, Dirk Bergemann, Marek Bojko
Efficient Dynamic Mechanism Design Without A Common Prior, Dirk Bergemann, Marek Bojko
Cowles Foundation Discussion Papers
We study efficient dynamic mechanism design with independent private values when agents do not share a common prior over the stochastic environment. Each agent privately observes the stochastic kernel governing the evolution of her own type and may hold arbitrary beliefs about the kernels of others. We extend the agents’ type space to include the kernel itself and show that the dynamic team mechanism of Athey and Segal (2013) and the dynamic pivot mechanism of Bergemann and Välimäki (2010) implement the socially efficient allocation in periodic ex-post equilibrium. We further show that kernels can be elicited only once, at the …
Clinical Outcomes After Ulnar Collateral Ligament Reconstruction With Palmaris Longus Versus Gracilis Autograft In Baseball Players: A Cohort Analysis, Michael C. Ciccotti, Brooks Martino, Frank Cautela, Nathaniel Tchangou, Daniel Kwak, Eric Didomenico, Harrison S. Fellheimer, Christopher C. Dodson, Steven B. Cohen, Michael G. Ciccotti
Clinical Outcomes After Ulnar Collateral Ligament Reconstruction With Palmaris Longus Versus Gracilis Autograft In Baseball Players: A Cohort Analysis, Michael C. Ciccotti, Brooks Martino, Frank Cautela, Nathaniel Tchangou, Daniel Kwak, Eric Didomenico, Harrison S. Fellheimer, Christopher C. Dodson, Steven B. Cohen, Michael G. Ciccotti
Rothman Institute Papers
BACKGROUND: Ulnar collateral ligament (UCL) reconstruction (UCLR) is a common procedure for overhead athletes, particularly baseball players sustaining partial or full UCL tears. Palmaris longus (PL) and gracilis (GR) autografts are the most frequently used graft sources, yet limited data compare clinical outcomes in baseball athletes.
PURPOSE: To compare patient-reported outcomes after UCLR with PL versus GR autografts in baseball players.
STUDY DESIGN: Cohort study; Level of evidence, 3.
METHODS: Patients who underwent isolated UCLR with either PL or GR autograft and a minimum of 2 years of follow-up were identified. All reconstructions were performed using the Modified Jobe or …
I’Ll Be Attending Hearings That Will Help Decide Whether Canadian Exports Will Face A New Tariff. Why Isn’T Ottawa Sending Anyone?, Barry Appleton
I’Ll Be Attending Hearings That Will Help Decide Whether Canadian Exports Will Face A New Tariff. Why Isn’T Ottawa Sending Anyone?, Barry Appleton
Other Publications
No abstract provided.
Aberrant Ciliogenesis Induced By Enhanced Bmp Signaling Causes Heterotopic Ossification, Hiroyuki Yamaguchi, Jianbo Wang, Fangfang Yan, Jiarui Bi, Radbod Darabi, William R. Lagor, Zhongming Zhao, Aris N. Economides, Yuji Mishina, Yoshihiro Komatsu
Aberrant Ciliogenesis Induced By Enhanced Bmp Signaling Causes Heterotopic Ossification, Hiroyuki Yamaguchi, Jianbo Wang, Fangfang Yan, Jiarui Bi, Radbod Darabi, William R. Lagor, Zhongming Zhao, Aris N. Economides, Yuji Mishina, Yoshihiro Komatsu
Faculty, Staff and Student Publications
Bone morphogenetic protein (BMP) signaling is a principal driver of heterotopic ossification (HO), yet how aberrant BMP activity structurally reprograms cellular signaling machinery to develop HO remains unclear. Here, we identify BMP signaling as a direct upstream regulator of ciliogenesis that coordinates a multi-stage, pro-osteochondrogenic signaling relay during HO. Using a conditional gain-of-function BMP mouse model (Acvr1Q207D/+), we demonstrate that enhanced BMP signaling promotes primary cilium biogenesis and axonemal elongation through canonical Smad1/5/9-dependent transcriptional activation of intraflagellar transport (IFT) Ift20, a core component of the IFT machinery. Rather than operating via a singular downstream cascade, these elongated …
Tranexamic Acid In High-Risk Shoulder Arthroplasty Patients: Safety Across Thromboembolic, Cardiac, Renal, And Neurologic Risk Profiles, Tarishi Parmar, Akin Adio, Asim Handy, Mohammad Daher, Alec Kellish, Adam Khan, Joseph A. Abboud
Tranexamic Acid In High-Risk Shoulder Arthroplasty Patients: Safety Across Thromboembolic, Cardiac, Renal, And Neurologic Risk Profiles, Tarishi Parmar, Akin Adio, Asim Handy, Mohammad Daher, Alec Kellish, Adam Khan, Joseph A. Abboud
Rothman Institute Papers
INTRODUCTION: Tranexamic acid (TXA) effectively reduces blood loss and transfusion requirements in shoulder arthroplasty. However, concerns regarding thromboembolic, neurologic, cardiac, and renal complications have limited its use in medically high-risk patients. This study evaluated temporal trends and the safety of TXA in high-risk patients undergoing total shoulder arthroplasty (TSA).
METHODS: A retrospective cohort study was conducted using TriNetX, identifying patients who underwent shoulder arthroplasty (2012-2025). Patients were stratified by preexisting high-risk conditions, including prior thromboembolism, renal failure, atrial fibrillation, seizure disorders, and visual disturbances. Within each subgroup, patients receiving TXA were propensity score-matched to those who did not. Perioperative TXA …
Energy Efficiency Limits And Future Electricity Demand Of Computing Devices, Ricardo Pinto, Tiago Domingos, Paul E. Brockway, Matthew Kuperus Heun, Tânia Sousa
Energy Efficiency Limits And Future Electricity Demand Of Computing Devices, Ricardo Pinto, Tiago Domingos, Paul E. Brockway, Matthew Kuperus Heun, Tânia Sousa
University Faculty Publications and Creative Works
- ICT (information and communication technologies) represented 4% of the world electricity consumption in 2020;
- Computing devices represented 2% of the world electricity consumption in 2020;
- In recent scenarios datacentre electricity demand reaches 3% of world electricity in 2030, and more than 4% in 2035
"In My Community, If You're An Addict, People Don't Just Look Down On You For The Drugs, But For Being Black, Too": Black And Latine Methadone Patients' Experiences Around Addiction, Methadone Treatment, And Intersectional Stigma, A.M. Ward, T. Wood, Donny Gerke, Suzan Walters, J. Williams, D. Clement, M. Katandu, D. Ferguson, K. Morrison, Yahya Alnashri, Benjamin Grin, Jessica Jaiswal
"In My Community, If You're An Addict, People Don't Just Look Down On You For The Drugs, But For Being Black, Too": Black And Latine Methadone Patients' Experiences Around Addiction, Methadone Treatment, And Intersectional Stigma, A.M. Ward, T. Wood, Donny Gerke, Suzan Walters, J. Williams, D. Clement, M. Katandu, D. Ferguson, K. Morrison, Yahya Alnashri, Benjamin Grin, Jessica Jaiswal
Faculty and Staff Publications
Background: Stigma surrounding opioid use disorder (OUD) and medications for opioid use disorder (MOUD), such as methadone, remains a significant barrier to care, despite the effectiveness of MOUD. Intersectional stigma tied to addiction, methadone treatment, structural racism, and classism disproportionately affects minoritized people with OUD, with direct consequences for health and wellbeing. Less is known about how Black and Latine people in methadone treatment think about and experience various dimensions of stigma related to addiction and the social determinants of health.
Methods: Semi-structured interviews were conducted with Black and Latine patients from two Newark, NJ, United States, methadone clinics (n …
Climate-Responsive Design For Sustainable Construction: Passive Strategies In Domestic Architecture Supporting Sustainability, Nahed Chakouf
Climate-Responsive Design For Sustainable Construction: Passive Strategies In Domestic Architecture Supporting Sustainability, Nahed Chakouf
All Works
This study explores climate-responsive design in domestic architecture, focusing on the application and effectiveness of passive strategies across various climatic regions, including the UK, hot-arid, tropical, and cold climates. A qualitative comparative case study method was used to explore different passive design strategies, integration of sustainability, procurement, the coordination of stakeholders, and compliance with regulations in residential architectural projects under varying climate conditions. Drawing from a combination of historical case studies and original architectural projects, the research evaluates how spatial configuration, material selection, solar orientation, shading, ventilation, and insulation are optimized to achieve thermal comfort and energy efficiency. In temperate …
Childhood Development Podcast Assignment, Masha Komolova
Childhood Development Podcast Assignment, Masha Komolova
Open Educational Resources
The assignment asks students to analyze how a particular aspect of their childhood has shaped them into a person they are today. Students will use literature review, interview with a caregiver, and their own reflection to analyze their childhood development and its effects on them. The assignment will be in the form of a podcast.
Ai-Resistant And Ai-Resilient Assessment In Higher Education: A Systematic Review Of Validity-Grounded Strategies, Institutional Frameworks, And Equity Implications, Asrat Genet Amnie
Ai-Resistant And Ai-Resilient Assessment In Higher Education: A Systematic Review Of Validity-Grounded Strategies, Institutional Frameworks, And Equity Implications, Asrat Genet Amnie
Publications and Research
The emergence of large language models has precipitated a fun damental disruption to higher education assessment. Conventional instruments are susceptible to AI-assisted completion, threatening construct validity across disciplines and institutional contexts. When submitted work reflects AI capability rather than student competency, the inferential chain from performance to qualifica tion is invalidated – a problem of design rather than detection. This systematic review makes two contributions. First, it theorises and grounds the distinction between AI-resistant assessment, which seeks to prevent or impede AI access through containment, and AI-resilient assessment, which assesses genuine human cogni tive performance of intrinsic educational value regardless …
Advancing Bioinformatics With Language Models: Components, Applications, And Perspectives, Jiajia Liu, Mengyuan Yang, Yankai Yu, Haixia Xu, Tiangang Wang, Kang Li, Xiaobo Zhou
Advancing Bioinformatics With Language Models: Components, Applications, And Perspectives, Jiajia Liu, Mengyuan Yang, Yankai Yu, Haixia Xu, Tiangang Wang, Kang Li, Xiaobo Zhou
Faculty, Staff and Student Publications
Large language models (LLMs) are deep learning-based artificial intelligence models that have achieved remarkable success in natural language processing. Typically composed of neural networks with billions of parameters, they are trained on massive unlabeled datasets using self-supervised or semi-supervised learning. Beyond language, LLMs hold immense potential for addressing complex bioinformatics challenges. This review provides a comprehensive overview of transformer-based model applications in genomics, transcriptomics, proteomics, drug discovery, and single-cell analysis. We discuss critical components, including tokenization strategies for diverse biological data, transformer architectures, attention mechanisms, and pretraining approaches. We also survey currently available foundation models and their downstream applications across …
“I Never Really Thought That Would Be Something To Talk About With My Doctor”: Developing A Theory-Led Decision Aid For College Students’ Substance Use Disclosure In Healthcare, Hayley Stahl
Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–
College students who use drugs face compounding barriers to disclosing substance use to healthcare providers, including uncertainty about health consequences and stigma-driven identity concerns. Existing disclosure tools address neither barrier in an integrated fashion. This explanatory sequential mixed-methods study examined how constructs from the Theory of Motivated Information Management (TMIM; Afifi & Weiner, 2004) and Stigma Management Communication (SMC; Meisenbach, 2010) theory suggest factors influencing substance use disclosure among college students and shape their lived disclosure experiences. In Study 1, simultaneous-entry multiple regression analyses revealed that communication efficacy was associated with information seeking, perceived benefits of disclosure were linked to …
The Role Of Cross-Cultural Connections In Leadership Identity Development: From Entry To Embodiment, Jennifer Okoliko
The Role Of Cross-Cultural Connections In Leadership Identity Development: From Entry To Embodiment, Jennifer Okoliko
Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–
Leadership identity development has received considerable attention in the literature, but most of what we know comes from studies focused on students in formal leadership programs or on the mentee’s side of mentoring relationships. Less understood is the mentor's leadership identity development journey and the role of culture in that process.
This study explores how mentors from low power distance cultural backgrounds who engaged with mentees from high power distance cultural backgrounds interpreted the impact of those experiences on their leadership identity development.
Using Interpretive Phenomenological Analysis (IPA), I conducted two semi-structured interviews with ten participants recruited from different formal …
Sales Innovativeness Climate And B2b Salesperson Performance: The Roles Of Persistence, Entrepreneurial Self-Efficacy And Creative Selling, John Charles Peter Edwards, Steven Peter D'Alessandro, Morgan Miles
Sales Innovativeness Climate And B2b Salesperson Performance: The Roles Of Persistence, Entrepreneurial Self-Efficacy And Creative Selling, John Charles Peter Edwards, Steven Peter D'Alessandro, Morgan Miles
Research outputs 2022 to 2026
Purpose: Persistence is widely viewed as essential for success in business to business (B2B) selling, yet it remains unclear how persistence translates into higher sales performance when selling requires experimentation and novel customer solutions. This study examines whether a perceived sales innovativeness climate enables persistence and entrepreneurial self-efficacy (ESE) and, in turn, creative selling, driving B2B sales performance.
Design/methodology/approach: An online survey of 346 US-based B2B salespeople was analyzed using partial least squares structural equation modelling (PLS-SEM).
Findings: The perceived sales-innovativeness climate is positively associated with ESE, persistence, and sales performance. Persistence is positively related to sales performance and ESE, …
A Core Outcome Measurement Set For Hyperemesis Gravidarum Research: A Consensus Study, Kate Maslin
A Core Outcome Measurement Set For Hyperemesis Gravidarum Research: A Consensus Study, Kate Maslin
School of Nursing and Midwifery
BackgroundOutcome reporting in hyperemesis gravidarum (HG) research lacks standardization, which hampers the aggregation of data. A core outcome set (COS) for HG research has been developed to increase standardization. While a COS represents which key outcomes should be measured, it does not describe how and when they should be measured. Our aim was to develop a consensus-based core outcome measurement set for HG complementing the existing COS for HG.MethodThis study included multiple phases: (1) systematic review to identify all existing outcome measurement instrument (OMI)s in HG research; (2) a consensus meeting with the steering committee of this study to vote …
A Systematic Survey Of Brachyuran Land Crabs In The Online Tropical Aquarium Trade, Ella Xanthe Whitaker, David L. Roberts, John I. Spicer, Lucy Millicent Turner
A Systematic Survey Of Brachyuran Land Crabs In The Online Tropical Aquarium Trade, Ella Xanthe Whitaker, David L. Roberts, John I. Spicer, Lucy Millicent Turner
School of Biological and Marine Sciences
Globally the tropical aquatic aquarium trade is a multi-million-dollar industry. Although marine ornamental fish and invertebrates are the main focus, tropical freshwater ornamental species including invertebrates (classed by the sector as semi-aquatic, such as land crabs) are also traded. Land crabs include both brachyurans (true crabs) and anomurans (false crabs, including hermit crabs). These are sourced from wild populations and/or tank-bred for use as ornamental commodity species. This global trade is unregulated and the full extent of the brachyuran land crab trade is unknown. Land crabs are important ecosystem engineers, and collection for the tropical freshwater/semi-aquatic aquarium industry is believed …
A Conserved Mechanism For Dimerization And Activation Of Superfamily 1a Uvrd-Family Helicases, Binh Nguyen, Kacey N Mersch, Ankita Chadda, Eric A Galburt, Timothy M Lohman
A Conserved Mechanism For Dimerization And Activation Of Superfamily 1a Uvrd-Family Helicases, Binh Nguyen, Kacey N Mersch, Ankita Chadda, Eric A Galburt, Timothy M Lohman
2020-Current year OA Pubs
DNA helicases are ATP-dependent motor proteins that catalyze duplex DNA unwinding and are involved in DNA repair, recombination, and replication restart. Prominent members of the non-hexameric SF1A UvrD-family helicases are Escherichia coli UvrD, Rep, Bacillus stearothermophilus PcrA, and Mycobacterium tuberculosis (Mtb) UvrD1. SF1A monomers are processive 3'-to-5' single-stranded DNA translocases but need to be activated to become DNA helicases. One mechanism of activation is dimerization. Whereas Rep, UvrD, and PcrA form non-covalent dimers, the Mtb UvrD1 helicase forms a redox-dependent covalent dimer. Dimerization of Mtb UvrD1 occurs between the same regulatory domain (2B) within each subunit stabilized by a disulfide …
Rapid Recovery Of Peripheral Oxygen Saturation In Hypoxic Covid-19 Patients With Ivermectin/Doxycycline/Zinc Multidrug Therapy, Sabine Hazan, Adriana C. Vidal, Eleftherios Gkioulekas, Anoja W. Gunaratne, Sibaish Dolai, Robert L. Clancy, Peter A. Mccullough, Thomas J. Borody
Rapid Recovery Of Peripheral Oxygen Saturation In Hypoxic Covid-19 Patients With Ivermectin/Doxycycline/Zinc Multidrug Therapy, Sabine Hazan, Adriana C. Vidal, Eleftherios Gkioulekas, Anoja W. Gunaratne, Sibaish Dolai, Robert L. Clancy, Peter A. Mccullough, Thomas J. Borody
School of Mathematical & Statistical Sciences Faculty Publications
Several combination therapies for the early outpatient treatment of COVID-19 were proposed by independent research groups at the onset of the pandemic during 2020 and 2021. In this observational study, we report on the outcomes of an off-label triple combination therapy, consisting of ivermectin, doxycycline, and zinc, with adjunct vitamin C and D3 supplementation, which was used on high-risk COVID-19 patients. These patients refused an initial recommendation to seek inpatient care, despite a high-risk presentation compounded with one or more comorbidities and/or severe hypoxia. Telemedicine was used to administer personalized treatment to patients at home, who did not have access …
Patients, Not Lab Values: Ethical Reflections On The Limits Of Reductionist Biology, Kody Park, Tai Metzger, Sung-Ki Lee, Abdullah Jalal, Christine Lin, Jasmanet Chahal, Kacie Park
Patients, Not Lab Values: Ethical Reflections On The Limits Of Reductionist Biology, Kody Park, Tai Metzger, Sung-Ki Lee, Abdullah Jalal, Christine Lin, Jasmanet Chahal, Kacie Park
Student Publications
No abstract provided.
Transformative Phygital Service Research (Tpsr): An Agenda For Future Research, Saadia Shabnam, Sanjit K. Roy, Yonathan Silvain Roten, Gaganpreet Singh, Taewon Suh, Hairong Li
Transformative Phygital Service Research (Tpsr): An Agenda For Future Research, Saadia Shabnam, Sanjit K. Roy, Yonathan Silvain Roten, Gaganpreet Singh, Taewon Suh, Hairong Li
Research outputs 2022 to 2026
Purpose – This paper aims to develop a transformative phygital service research (TPSR) framework to explain how hybrid physical-digital service systems shape consumer well-being, autonomy, dignity and inclusion. While prior phygital service research (PSR) advances understanding of hybrid experiences and human-centred ecosystems, key ambiguities persist around agency, governance and interpretive labour in algorithmically mediated interactions. Existing frameworks address value co-creation but lack clarity on how digitally enforced rules and redistributed labour drive transformation. TPSR addresses this gap by theorising contradiction-driven processes through which human–AI arrangements and socio-technical dynamics produce both empowering and erosive outcomes in phygital service environments. Design/methodology/approach – …
Elective Genomic Sequencing For Adults In Research, Clinical And Commercial Contexts, Michael D Linderman, Sophia M Adelson, Tala M Berro, Jennifer L Anderson, Scott D Crawford, Tshaka J Cunningham, Edward D Esplin, Altovise T Ewing-Crawford, Daiva E Nielsen, Stacey Pereira, Tara Schmidlen, Heather Andrighetti, Steven B Bleyl, George M Church, Eden V Haverfield, Madhuri Hegde, Lazaridis N Konstantinos, Paul Kruszka, Debra Leonard, Thomas May, Molly Mcginniss, Vaibhav Pandya, Eric E Schadt, Bastian Greshake Tzovaras, Bethany Zettler, Amy L Mcguire, Robert C Green
Elective Genomic Sequencing For Adults In Research, Clinical And Commercial Contexts, Michael D Linderman, Sophia M Adelson, Tala M Berro, Jennifer L Anderson, Scott D Crawford, Tshaka J Cunningham, Edward D Esplin, Altovise T Ewing-Crawford, Daiva E Nielsen, Stacey Pereira, Tara Schmidlen, Heather Andrighetti, Steven B Bleyl, George M Church, Eden V Haverfield, Madhuri Hegde, Lazaridis N Konstantinos, Paul Kruszka, Debra Leonard, Thomas May, Molly Mcginniss, Vaibhav Pandya, Eric E Schadt, Bastian Greshake Tzovaras, Bethany Zettler, Amy L Mcguire, Robert C Green
Center for Medical Ethics and Health Policy Staff Publications
Purpose: Elective genomic sequencing (EGS) returns monogenic disease findings in multiple genes, including potentially novel variants, and may also provide participants with carrier status, pharmacogenomic and other health-related information. The PeopleSeq Study assessed participants' motivations for and concerns about EGS and the associated clinical and psychosocial outcomes across diverse EGS providers.
Methods: We administered a shared questionnaire to participants who chose to undergo EGS via 18 academic, clinical, or commercial EGS platforms.
Results: We enrolled 1575 participants, of whom 1147 (72.8%) completed a questionnaire after receiving their EGS results. A majority (60.3%) of the participants who completed a post-result questionnaire …
Multiplexed Plasmon-Enhanced Lateral Flow Assay For Early Diagnosis Of Acute Kidney Injury, Heng Guo, Yuxiong Liu, Ravi Jada, Ying Liu, Carissa Ng, Aquiles Payte, Jiaying Xu, Connor Malone, Jie Zhao, Kedhareswara Sairam Pasupuleti, Arda Aidan Arikan, Sameer Thadani, Srikanth Singamaneni, Ayse Akcan Arikan, Limei Tian
Multiplexed Plasmon-Enhanced Lateral Flow Assay For Early Diagnosis Of Acute Kidney Injury, Heng Guo, Yuxiong Liu, Ravi Jada, Ying Liu, Carissa Ng, Aquiles Payte, Jiaying Xu, Connor Malone, Jie Zhao, Kedhareswara Sairam Pasupuleti, Arda Aidan Arikan, Sameer Thadani, Srikanth Singamaneni, Ayse Akcan Arikan, Limei Tian
Faculty, Staff and Students Publications
Early diagnosis of acute kidney injury (AKI) remains a major clinical challenge due to the delayed and insensitive nature of conventional markers such as serum creatinine. Urinary protein biomarkers, including neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C (CysC), provide earlier and complementary information on kidney injury, but their clinical translation is limited by the lack of rapid, quantitative, and multiplexed point-of-care (POC) diagnostic tests. Here, we report a multiplexed plasmonic-fluor-based lateral flow assay (p-LFA) that enables sensitive, quantitative, and simultaneous detection of NGAL and CysC. By harnessing ultrabright plasmonic-fluor nanolabels and ratiometric fluorescence analysis, the p-LFA achieves picogram-per-milliliter analytical sensitivity …
A Process For The Preparation Of (S)-3-Amino-3-(4-Chlorophenyl)Propan-1-Ol, Msn Laboratories Private Limited, R&D Center, Hyderabad, India, Srinivasan Thirumalai Rajan, Srinivas Reddy Gade, Suresh Challa.
A Process For The Preparation Of (S)-3-Amino-3-(4-Chlorophenyl)Propan-1-Ol, Msn Laboratories Private Limited, R&D Center, Hyderabad, India, Srinivasan Thirumalai Rajan, Srinivas Reddy Gade, Suresh Challa.
Defensive Publications Series
The present disclosure relates to a process for the preparation of (S)-3-amino-3-(4-chlorophenyl)propan-1-ol of formula-1, which is represented by the following structural formula.
Formula-1
Websites Of Pharmacy Colleges: A Webometric Analysis, Yashwant S. Chaudhari Mr., Hemant S. Bhoye
Websites Of Pharmacy Colleges: A Webometric Analysis, Yashwant S. Chaudhari Mr., Hemant S. Bhoye
Library Philosophy and Practice (e-journal)
In the digital era, institutional websites act as the primary gateway for disseminating academic information, services, and research output. Webometric analysis is a quantitative method used to evaluate the performance, visibility, and impact of websites based on web-based indicators such as hyperlinks, web pages, and parts of web pages. This study examines 17 pharmacy colleges in Nashik district, out of a total of 63 pharmacy colleges affiliated to Savitribai Phule Pune University, Pune. The study examines domain extensions, number of web pages, internal and external links, and availability of library webpages. It also evaluates content features such as academic information, …
Technical Disclosure: The Urban Biosphere Ziggurat (Ubz), Affordable Housing And Urban Planning, Christopher L. Eckes
Technical Disclosure: The Urban Biosphere Ziggurat (Ubz), Affordable Housing And Urban Planning, Christopher L. Eckes
Defensive Publications Series
Current high-density urban housing models in the United States routinely fail because they optimize strictly for initial cost-per-square-foot, resulting in double-loaded corridor containment layouts that restrict natural light, induce community stagnation, and induce severe benefit "cliff effects" on upwardly mobile residents. The Urban Biosphere Ziggurat (UBZ) framework resolves this systemic crisis by decoupling high-tech, factory-precise structural engineering from regional, artistic architectural cladding. This disclosure outlines a scalable, non-speculative structural chassis integrated into a Community Land Trust (CLT) and Limited-Equity Housing Cooperative (LEHC) [1.5] governance ecosystem, permanently divesting real estate from predatory international speculation. [1]
To maximize municipal feasibility …