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Tetanus In An Intensive Care Unit Of A Turkish Hospital: Patient Analysis Of A 6-Year Period, Behi̇ce Kurtaran, Emre Karakoç, Aslihan Candevi̇r, Süheyla Kömür, Ayşe Seza İnal, Fi̇li̇z Ki̇bar, Yeşi̇m Taşova, Neşe Saltoğlu, Hasan Sali̇h Zeki̇ Aksu
Tetanus In An Intensive Care Unit Of A Turkish Hospital: Patient Analysis Of A 6-Year Period, Behi̇ce Kurtaran, Emre Karakoç, Aslihan Candevi̇r, Süheyla Kömür, Ayşe Seza İnal, Fi̇li̇z Ki̇bar, Yeşi̇m Taşova, Neşe Saltoğlu, Hasan Sali̇h Zeki̇ Aksu
Turkish Journal of Medical Sciences
To retrospectively evaluate the clinical features of patients admitted to the medical intensive care unit (ICU) of our hospital between January 2001 and May 2007 due to tetanus. Materials and methods: Patient vaccination history, incubation period, nosocomial infections, noninfectious conditions, mortality, and length of stay in the ICU and hospital were documented. Results: Fifteen tetanus patients were admitted during the 6-year period. Mean age of the patients (9 male, 6 female) was 60 ± 13 years. Median length of stay was 42 days (range: 30-77 days) for survivors and 7 days (range: 1-59 days) for non-survivors. Mortality was consequent to …
Asymptomatic Carriage Of Bacteria In Food Workers In Nilüfer District, Bursa, Turkey*, Kayihan Pala, Cüneyt Özakin, Nalan Akiş, Melda Sinirtaş, Suna Gedi̇koğlu, Hamdi̇ Ayteki̇n
Asymptomatic Carriage Of Bacteria In Food Workers In Nilüfer District, Bursa, Turkey*, Kayihan Pala, Cüneyt Özakin, Nalan Akiş, Melda Sinirtaş, Suna Gedi̇koğlu, Hamdi̇ Ayteki̇n
Turkish Journal of Medical Sciences
This study was carried out in order to determine the nasal carriage of Staphylococcus aureus and the faecal carriage of Salmonella spp., Shigella spp., Yersinia enterocolitica, Listeria monocytogenes, and Escherichia coli O157:H7 in food industry workers. Materials and methods: During the study, face to face interviews were conducted with the workers and 9-item questionnaires regarding demographic information, working time, and periodical medical examinations were administered. In the study nasal swab specimens of 1115 individuals and faecal specimens of 1061 individuals were bacteriologically investigated. Results: The nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) was found to be significantly more common in …
Hospital-Acquired Pneumonia In Nonintensive Care Unit Wards, Meltem Avci, Onur Özgenç, Ayten Coşkuner, Berna Bozca, Levent Kidak, Gülşen Mermut, Mehmet Sezai̇ Taşbakan, Nesli̇han Genç, Gülşen Güloğlu, Alpay Ari
Hospital-Acquired Pneumonia In Nonintensive Care Unit Wards, Meltem Avci, Onur Özgenç, Ayten Coşkuner, Berna Bozca, Levent Kidak, Gülşen Mermut, Mehmet Sezai̇ Taşbakan, Nesli̇han Genç, Gülşen Güloğlu, Alpay Ari
Turkish Journal of Medical Sciences
To determine the incidence, risk factors, etiology, and antibiotic susceptibility of hospital-acquired pneumonia (HAP) in nonintensive care units (non-ICU) and nonintubated adult patients. Materials and methods: A prospective surveillance study was performed from January 2006 through December 2007 in the medical and surgical wards of the İzmir Teaching and Research Hospital. Results: During the study period, data on 57,133 patients with a total of 413,515 patient-days were analyzed. A total of 106 HAP episodes occurred in 99 patients. The infection rate per 100 patients and per 1000 patient-days was found to be 0.2% and 0.3%, respectively. HAP episodes were detected …
Genotyping Of Trichosporon Asahii Strains Isolated From Urinary Tract Infections In A Turkish University Hospital, Zeynep Ceren Karahan, Esra Koyuncu, Istar Dolapçi, Özay Arikan Akan, Füsun Can, Alper Tekeli̇
Genotyping Of Trichosporon Asahii Strains Isolated From Urinary Tract Infections In A Turkish University Hospital, Zeynep Ceren Karahan, Esra Koyuncu, Istar Dolapçi, Özay Arikan Akan, Füsun Can, Alper Tekeli̇
Turkish Journal of Medical Sciences
Trichosporon infections are associated with a wide spectrum of clinical manifestations. Trichosporon asahii is the most important species in the genus. Our aim was to evaluate the genotypic relatedness of urinary T. asahii strains isolated from immunocompetent patients during a hospital outbreak. Materials and methods: Twenty-three T. asahii isolates obtained from 15 patients hospitalized in different wards of Ankara University Ibn-i Sina Hospital between July 2004 and April 2005 were studied. T. asahii was identified by API 20C AUX (BioMérieux Vitek, Hazelwood, USA) system and confirmed by genus and species specific polymerase chain reactions. Genetic relatedness of the isolates was …
The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r
The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r
Turkish Journal of Medical Sciences
Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens. They also contribute to the innate resistance against microbial pathogens. The present study examined the effect of microorganisms such as Escherichia coli (E. coli), Serratia marcescens (S. marcescens), Methicillin-resistant Staphylococcus aureus (MRSA), coagulase negative staphylococci (CoNS), and Candida albicans (C. albicans) on cytokine secretion in bone marrow-dendritic cells (BM-DCs). Materials and methods: The levels of cytokines in culture supernatants of the BM-DC were determined by enzyme-linked immunosorbent assay. Results: DCs stimulated by microorganisms produced large amounts of TNF-\alpha, IL-1\beta, IL-6, and IL-10. The …
Absence Of Vancomycin-Resistant Enterococci (Vre) Despite The Presence Of Risk Factors: A Survey Of Rectal Carriage Of Vre*, Zeli̇ha Koçak Tufan, Selcan Arslan, Sali̇h Cesur, Cemal Bulut, Hasan Irmak, Sami̇ Kinikli, Ferah Ergi̇n, Ali̇ Kutta Çeli̇k, Ali̇ Pekcan Demi̇röz
Absence Of Vancomycin-Resistant Enterococci (Vre) Despite The Presence Of Risk Factors: A Survey Of Rectal Carriage Of Vre*, Zeli̇ha Koçak Tufan, Selcan Arslan, Sali̇h Cesur, Cemal Bulut, Hasan Irmak, Sami̇ Kinikli, Ferah Ergi̇n, Ali̇ Kutta Çeli̇k, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
The resistant organisms from patients and healthcare workers (HCWs) first colonized the gastrointestinal tract before causing infections in patients. In this study, presence of risk factors for vancomycin-resistant enterococci (VRE) colonization and the prevalence of rectal carriage of VRE among HCWs and hospitalized patients in the absence of an outbreak were investigated. Design: Cross-sectional study. Setting: A 600-bed training and research hospital. Materials and methods: A total of 508 intensive-care unit (ICU) patients and HCWs in these units were included. Risk factors such as previous antibiotic use, especially vancomycin and cephalosporin, the presence of invasive devices like catheters, and co-morbid …
Serum Adenosine Deaminase Activity And The Total Antioxidant Capacity Of Plasma In Pulmonary Tuberculosis And Non-Tuberculosis Pulmonary Disease, Mohammad Naderi, Mohammad Hashemi, Ali Mehdizadeh, Hamid Mehrabifar, Hamid Reza Kouhpayeh, Hossein Ansari, Gholamreza Bahari, Saeid Ghavami
Serum Adenosine Deaminase Activity And The Total Antioxidant Capacity Of Plasma In Pulmonary Tuberculosis And Non-Tuberculosis Pulmonary Disease, Mohammad Naderi, Mohammad Hashemi, Ali Mehdizadeh, Hamid Mehrabifar, Hamid Reza Kouhpayeh, Hossein Ansari, Gholamreza Bahari, Saeid Ghavami
Turkish Journal of Medical Sciences
The aim of this study was to investigate the level of serum adenosine deaminase (ADA) and the total antioxidant capacity (TAC) in pulmonary tuberculosis (PTB), non-tuberculosis pulmonary disease (non-PTB) and healthy subjects. Materials and methods: Serum ADA activity was measured using the Giusti and Galanti method, and the total antioxidant capacity of plasma was determined by the ferric reducing ability of plasma (FRAP) test. Results: The serum ADA levels were significantly higher (P < 0.001) in pulmonary TB (PTB, 19.78 ± 7.09 U/L), as well as in non-PTB patients (14.78 ± 4.65 U/L) when compared to healthy controls (10.02 ± 1.99 U/L). The sensitivity and specificity were found to be 71.7% and 63.3%, respectively, in distinguishing PTB from non-PTB. In distinguishing PTB from healthy subjects, the sensitivity and specificity were 87% and 93.3%, respectively. The TAC was significantly lower in PTB (485.2 ± 190.0 µM) and non-PTB patients (588.3 ± 195.8 µM), when compared to the controls (784.3 ± 190.0 µM; P < 0.001). Plasma antioxidative activity decreased in PTB and non-PTB patients when compared to the controls. Conclusion: We concluded that serum ADA activity is not a useful test to differentiate pulmonary TB from other respiratory diseases. The TAC is low in pulmonary TB, therefore supplementation with a suitable anti-oxidant may be useful.
Effects Of Vitamin A And C And Melatonin On 3-Nitrotyrosine Formation In Guinea Pig Heart Under Lipopolysaccharide-Induced Stress, Hali̇l Yaman, Tuncer Çayci, Meli̇k Seyrek, Emi̇n Özgür Akgül, Yasemi̇n Gülcan Kurt, İbrahi̇m Aydin, Hakan Yaren, Erdi̇nç Çakir, Ömer Özcan, Behzat Çi̇men, Nurten Türközkan, Mehmet Kemal Erbi̇l
Effects Of Vitamin A And C And Melatonin On 3-Nitrotyrosine Formation In Guinea Pig Heart Under Lipopolysaccharide-Induced Stress, Hali̇l Yaman, Tuncer Çayci, Meli̇k Seyrek, Emi̇n Özgür Akgül, Yasemi̇n Gülcan Kurt, İbrahi̇m Aydin, Hakan Yaren, Erdi̇nç Çakir, Ömer Özcan, Behzat Çi̇men, Nurten Türközkan, Mehmet Kemal Erbi̇l
Turkish Journal of Medical Sciences
Bacterial lipopolysaccharide (LPS) triggers synthesis of nitric oxide (NO) and superoxide (O_2^{.-}). O_2^{.-} can react with NO to produce the powerful oxidant peroxynitrite (ONOO-). The presence of 3-nitrotyrosine (3-NT) in tissues is often used as a marker of ONOO- production. Vitamin A, vitamin C, and melatonin are potent antioxidant molecules. We sought to clarify this issue by examining the effects of vitamin A (15,000 IU/kg/day), vitamin C (600 mg/kg/day), and melatonin (25 mg/kg) on 3-NT formation in heart tissue in a guinea pig model of LPS-induced endotoxemia. Materials and methods: A total of 75 animals were randomly divided into 5 …
Prevalence Of Anaemia In Women Of Reproductive Age In Meghalaya: A Logistic Regression Analysis, Sanku Dey, Sankar Goswami, Madhuchhanda Goswami
Prevalence Of Anaemia In Women Of Reproductive Age In Meghalaya: A Logistic Regression Analysis, Sanku Dey, Sankar Goswami, Madhuchhanda Goswami
Turkish Journal of Medical Sciences
To examine the prevalence of anaemia in Meghalaya, India, by exploring the 2005-2006 National Family Health Survey (NFHS -3) data. Materials and methods: The study population consisted of 3934 ever-married women of reproductive age (15-49 years) from the state Meghalaya, India, which were taken from the NFHS-3 survey, to explore the predictors responsible for the prevalence of anaemia by using different background characteristics such as age, place of residence, nutritional status, number of children ever born, pregnancy status, educational achievement, and economic status. As a response variable, anaemia levels were categorised as a dichotomous variable, and the predicted probabilities were …
Two Siblings With Netherton Syndrome, Selma Emre, Ahmet Meti̇n, D. Deni̇z Demi̇rseren, Ahu Yorulmaz, Aykut Onursever, Burçi̇n Kaftan
Two Siblings With Netherton Syndrome, Selma Emre, Ahmet Meti̇n, D. Deni̇z Demi̇rseren, Ahu Yorulmaz, Aykut Onursever, Burçi̇n Kaftan
Turkish Journal of Medical Sciences
Netherton syndrome (NS) is a rare genodermatosis characterized by autosomal recessive inheritance pattern, unknown etiology, ichthyosiform cutaneous changes, atopic diathesis, and alterations in the hair shaft. As a result of aging coupled with immune deficiency, clinical symptoms may vary. Herein, we present 2 siblings with the characteristic cutaneous symptoms of NS, albeit with some differences between the siblings. Materials and methods: Two sisters presented to our clinic with sparse and brittle hair along with pruritic, erythematous, and scaling cutaneous lesions. Both patients underwent a clinical examination and laboratory analyses. Results: Based on the clinical and laboratory findings, both patients were …
Incidence And Risk Factors For Bloodstream Infections Stemming From Temporary Hemodialysis Catheters, Hati̇ce Rahmet Çaylan, Gürdal Yilmaz, Ebru Emel Sözen, Kemaletti̇n Aydin, İftahar Köksal
Incidence And Risk Factors For Bloodstream Infections Stemming From Temporary Hemodialysis Catheters, Hati̇ce Rahmet Çaylan, Gürdal Yilmaz, Ebru Emel Sözen, Kemaletti̇n Aydin, İftahar Köksal
Turkish Journal of Medical Sciences
Catheter-related bloodstream infection (CR-BSI) is considered as an important complication of hemodialysis catheters. The purpose of this prospective study was to evaluate the incidence and risk factors of temporary hemodialysis catheter-related bloodstream infection. Materials and methods: Prospective data related to temporary hemodialysis catheters inserted in our institution were collected for duration of three years. The risk factors of CR-BSI of patients between the CR-BSI group and the control group were compared. Results: A total of 248 temporary hemodialysis catheters were inserted in 201 patients and remained in situ for a cumulative total of 5192 catheter days. There were 3254 dialysis …
Levels Of Haemophilus Influenzae Type B (Hib) Antibody In Turkey Before Routine Immunization, Cemi̇le Sönmez, Ni̇lay Çöplü, Demet Kurtoğlu, Berri̇n Esen, Annette Crowley Luke, Lorraine Ransley, Ayşegül Gözalan
Levels Of Haemophilus Influenzae Type B (Hib) Antibody In Turkey Before Routine Immunization, Cemi̇le Sönmez, Ni̇lay Çöplü, Demet Kurtoğlu, Berri̇n Esen, Annette Crowley Luke, Lorraine Ransley, Ayşegül Gözalan
Turkish Journal of Medical Sciences
The Haemophilus influenzae type b (Hib) vaccine was introduced into the routine immunization schedule in Turkey on January 1, 2007. This study investigates the immunity to Hib prior to the introduction of the vaccine. Materials and methods: Serum samples were collected from healthy volunteers between the ages of 6 months and 50 + years of age, living in the area of 26 health centers in the Samsun, Antalya, and Diyarbakir provinces during 2000-2001. In total, 1713 sera were selected for this study, and the younger age groups were given priority (range 0-82). A commercial ELISA test was used to measure …
Prevalence Of Helicobacter Pylori Infection In Healthcare Workers, Maliheh Metanat, Batool Sharifi-Mood, Shahrokh Izadi
Prevalence Of Helicobacter Pylori Infection In Healthcare Workers, Maliheh Metanat, Batool Sharifi-Mood, Shahrokh Izadi
Turkish Journal of Medical Sciences
Helicobacter pylori (H. pylori) is a major factor in inflammatory and malignant diseases of the gastrointestinal tract. The epidemiologic pattern of this infection varies among developed and developing countries, and is related to the general standards of living in each region. In view of the importance of this infection and its different prevalence in different regions of Iran, as well as its long-term complications, this study was conducted to investigate the prevalence of H. pylori infection and its contributing factors in Zahedan. Materials and methods: Ninety-seven healthcare workers without digestive symptoms or a history of H. pylori eradication were randomly …
Evaluation Of The Knowledge Of Hospital Cleaning Staff About Prevention Of Nosocomial Infections, Tansu Yamazhan, Meltem Işikgöz Taşbakan, Şebnem Çalik, Hüsnü Pullukçu, Oğuz Reşat Si̇pahi̇, Sercan Ulusoy
Evaluation Of The Knowledge Of Hospital Cleaning Staff About Prevention Of Nosocomial Infections, Tansu Yamazhan, Meltem Işikgöz Taşbakan, Şebnem Çalik, Hüsnü Pullukçu, Oğuz Reşat Si̇pahi̇, Sercan Ulusoy
Turkish Journal of Medical Sciences
Aims: Detection of risk groups and infection sources and awareness of the routes of transmission of infections are important for prevention of hospital infections. In this study, we aimed to evaluate the knowledge level and the behavior models of hospital cleaning staff about nosocomial infections. Materials and Methods: A 21-item questionnaire about nosocomial infections was administered to the hospital cleaning staff. Results: Out of 290 hospital cleaning staff, 240 (82.7%, 122 male, 118 female, aged 36.2±8.7) were included in the study. When evaluated according to their educational status, 55.4% had graduated from primary school. Fifty-four percent of the staff had …
Viral Etiology And Symptoms Of Acute Upper Respiratory Tract Infections In Children, Emi̇n Ünüvar, İsmai̇l Yildiz, Ayşe Kiliç, Seyhan Selvi̇ Aslan, Bülent Çakal, Sadik Toprak, Seli̇m Badur, Fatma Oğuz, Müjgan Sidal
Viral Etiology And Symptoms Of Acute Upper Respiratory Tract Infections In Children, Emi̇n Ünüvar, İsmai̇l Yildiz, Ayşe Kiliç, Seyhan Selvi̇ Aslan, Bülent Çakal, Sadik Toprak, Seli̇m Badur, Fatma Oğuz, Müjgan Sidal
Turkish Journal of Medical Sciences
Aims: To determine viral causes of acute upper respiratory tract infections and clinical findings in children living in Istanbul, Turkey. Materials and Methods: This prospective study was carried out in 234 outpatient children (age range: 1-180 months) with acute upper respiratory tract infections, seen in the outpatient clinic at Istanbul Medical School Children´s Hospital. After clinical findings were recorded, nasal swab specimens were taken. In 201 specimens collected, influenza-A and -B, adenovirus, respiratory syncytial virus, and parainfluenza viruses were studied using direct fluorescence antibody, polymerase chain reaction (PCR), and cell culture techniques. Results: Rate of virus isolation was 29.8% (60/201). …
Screening For Chlamydia Trachomatis Infection Using Direct Fluorescein Antibody Method In Female Sex Workers Registered In Ankara, Turkey: Pros And Cons, Pinar Zarakolu, Server Yağci, Banu Çakir, Serhat Ünal
Screening For Chlamydia Trachomatis Infection Using Direct Fluorescein Antibody Method In Female Sex Workers Registered In Ankara, Turkey: Pros And Cons, Pinar Zarakolu, Server Yağci, Banu Çakir, Serhat Ünal
Turkish Journal of Medical Sciences
Aim: This study aimed to screen for Chlamydia trachomatis infection by direct fluorescein antibody (DFA) method in a high-risk population, registered female sex workers (FSWs) in Ankara, Turkey, to investigate the advantages and disadvantages of using this method in a routine screening program of the FSW population. Materials and Methods: All registered FSWs (n = 152) in Ankara were enrolled in the study. None of them were showing any genital signs or symptoms of sexually transmitted infections (STIs). Endocervical swabs were collected and examined for C. trachomatis by DFA method (Fluorotect Chlamydia, Omega Diagnostics, UK). Cellular adequacy of the specimens …
Examining Antibiotic Use At An Education And Research Hospital In Turkey: Point Prevalence Results, Gül R. Yilmaz, Cemal Bulut, Fati̇h Yildiz, Selcan Arslan, M. Arzu Yetki̇n, Ali̇ Pekcan Demi̇röz
Examining Antibiotic Use At An Education And Research Hospital In Turkey: Point Prevalence Results, Gül R. Yilmaz, Cemal Bulut, Fati̇h Yildiz, Selcan Arslan, M. Arzu Yetki̇n, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
Aims: Antimicrobial drugs are among the most commonly prescribed drugs in hospitals. Inappropriate use of antibiotics leads to development of antimicrobial resistance. The aims of this study were to determine the rate of antibiotic usage in hospitalized patients, the reasons for antibiotic therapy, irrational uses, and the rates of irrational use in patients hospitalized in Ankara Education and Research Hospital. Materials and Methods: A point prevalence surveillance study was performed on 27 April 2006 at Ankara Education and Research Hospital. Data of all hospitalized patients were collected. Results: On the day of the study, 153 patients (36.2%) out of 422 …
Necrosis In Human Cystic Echinococcosis: An Underrecognized Tissue Reaction Possibly Related To Host Response, Özlem Mi̇man, Meti̇n Atambay, Nasuhi̇ Engi̇n Aydin, Ni̇lgün Daldal
Necrosis In Human Cystic Echinococcosis: An Underrecognized Tissue Reaction Possibly Related To Host Response, Özlem Mi̇man, Meti̇n Atambay, Nasuhi̇ Engi̇n Aydin, Ni̇lgün Daldal
Turkish Journal of Medical Sciences
Aim: As Echinococcosis stands out worldwide as an important zoonotic cestode infection caused by various Echinococcus species, histopathological features of the disease are worthy of in-depth study. Materials and Methods: Histopathological changes in adjacent parenchymal tissue in patients with cystic echinococcosis (CE) were evaluated. The study included 91 patients 4-80 years of age (mean age: 36.24 years). Results: The histopathological findings of 83 specimens were as follows: fibrosis: 77.11%; mono-nucleated cells: 71.08%; necrosis: 67.47%; eosinophils: 51.80%; giant cells: 31.33%; neutrophils: 8.43%. Fibrosis, eosinophils, neutrophils, and giant cell infiltration were observed significantly more often than mono-nucleated cell infiltration, germinal membranes, and …
Epidemiology Of Human Rabies In Turkey: 1992-2007, Turan Buzgan, Hasan Irmak, Gül R. Yilmaz, Mehmet Ali̇ Torunoğlu, Ahmet Safran
Epidemiology Of Human Rabies In Turkey: 1992-2007, Turan Buzgan, Hasan Irmak, Gül R. Yilmaz, Mehmet Ali̇ Torunoğlu, Ahmet Safran
Turkish Journal of Medical Sciences
Aim: Rabies continues to be a public health problem in Turkey; however, the number of reported cases has decreased in recent years and 1-2 cases of human rabies are reported annually to the Ministry of Health (MoH). Epidemiological and demographic features, clinical findings, and prophylaxis of human rabies reported to the MoH between 1992 and 2007 were evaluated. Materials and Methods: Rabies has been reported in Turkey since 1930. Data on human rabies have been available from the MoH since 1992. In this study, data on human rabies were analyzed retrospectively. The provinces, rabies risk exposure date, age, gender, type …
Survival Of Certain Nosocomial Infectious Agents On The Surfaces Of Various Covering Materials, Hali̇l Yazgi, M. Hami̇dullah Uyanik, Mustafa Ertek, Ayşe Esi̇n Aktaş, Hakan İgan, Ahmet Ayyildiz
Survival Of Certain Nosocomial Infectious Agents On The Surfaces Of Various Covering Materials, Hali̇l Yazgi, M. Hami̇dullah Uyanik, Mustafa Ertek, Ayşe Esi̇n Aktaş, Hakan İgan, Ahmet Ayyildiz
Turkish Journal of Medical Sciences
Aim: The aim of the present study was to investigate the survival time of some nosocomial infectious agents on the surface of various covering materials. Materials and Methods: Four kinds of flooring materials (vinyl and ceramic tile as floor covering material; and laminate and inox sheet as bench covering material) were experimentally contaminated with Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and vancomycin-resistant (VR) Enterococcus faecalis, which were frequently encountered in nosocomial infections. The survival periods of representative agents on the tested flooring materials were detected by culturing from the surfaces. Results: It was found that the survival periods were shorter …
Antimicrobial Susceptibility, Inducible Macrolide-Lincosamide-Streptogramin B, And Clonal Diversity Patterns Of Nosocomial Methicillin-Resistant Staphylococcus Aureus Strains Isolated In Hacettepe University Adult Hospital, Pinar Zarakolu, Gökhan Metan, Belgi̇n Altun, Gülşen Hasçeli̇k, Serhat Ünal
Antimicrobial Susceptibility, Inducible Macrolide-Lincosamide-Streptogramin B, And Clonal Diversity Patterns Of Nosocomial Methicillin-Resistant Staphylococcus Aureus Strains Isolated In Hacettepe University Adult Hospital, Pinar Zarakolu, Gökhan Metan, Belgi̇n Altun, Gülşen Hasçeli̇k, Serhat Ünal
Turkish Journal of Medical Sciences
Aim: Nosocomial infections due to methicillin resistant Staphylococcus aureus (MRSA) are an important problem with limited therapeutic options. The aim of this study was to determine the vancomycin, teicoplanin, linezolid, tigecycline, erythromycin, gentamicin, ciprofloxacin, rifampin, trimethoprim/sulfamethoxazole, and clindamycin susceptibility, inducible macrolide-lincosamide-streptogramin B (iMLS_B) resistance, and clonal diversity patterns of 109 mecA positive Staphylococcus aureus strains isolated from patients with nosocomial infections in Hacettepe University Adult Hospital between 2002 and 2004. Materials and methods: The nosocomial isolates of S. aureus from various clinical samples (58 blood, 45 pus, 6 catheter) were identified by Sceptor (Becton Dickinson, USA) automated system. Polymerase chain …
Prevalence Of Echinococcus Granulosus Detected Using Enzyme Immunoassay And Abdominal Ultrasonography In A Group Of Students Staying In A State Dormitory In Turkey, Bi̇lgi̇n Arda, Hüsnü Pullukçu, Tansu Yamazhan, Oğuz Reşat Si̇pahi̇, Sadik Tamsel, Gülgün Demi̇rpolat, Meti̇n Korkmaz
Prevalence Of Echinococcus Granulosus Detected Using Enzyme Immunoassay And Abdominal Ultrasonography In A Group Of Students Staying In A State Dormitory In Turkey, Bi̇lgi̇n Arda, Hüsnü Pullukçu, Tansu Yamazhan, Oğuz Reşat Si̇pahi̇, Sadik Tamsel, Gülgün Demi̇rpolat, Meti̇n Korkmaz
Turkish Journal of Medical Sciences
Aim: In this study our aim was to analyse the seroprevalence of cystic echinococcosis and prevalence of lesions (with abdominal ultrasonography) in a group of young adult university students staying in a state dormitory in Bornova, İzmir, Turkey. Materials and methods: The study group was consisted of 750 students (360 women, 390 men, mean age 20.92 ± 1.82 years, min 17, max 29). Informed written consent was obtained from each student and they were requested to fill a questionnaire form (sociocultural and economic condition, area of living, and demographic data). Blood sampling was performed by intravenous puncture and sera were …
Anti-Hav Seroprevalence In Turkish Military Personnel And Its Relation With Demographic Properties, Hanefi̇ Cem Gül, İsmai̇l Yaşar Avci, Ömer Coşkun, Recai̇ Oğur, Yakup Hakan Başaran, Çakir Güney, Bülent A. Beşi̇rbelli̇oğlu, Cengi̇z Han Açikel, Can Polat Eyi̇gün, Alaaddi̇n Pahsa
Anti-Hav Seroprevalence In Turkish Military Personnel And Its Relation With Demographic Properties, Hanefi̇ Cem Gül, İsmai̇l Yaşar Avci, Ömer Coşkun, Recai̇ Oğur, Yakup Hakan Başaran, Çakir Güney, Bülent A. Beşi̇rbelli̇oğlu, Cengi̇z Han Açikel, Can Polat Eyi̇gün, Alaaddi̇n Pahsa
Turkish Journal of Medical Sciences
Aim: Turkey is a middle endemic area in terms of Hepatitis A Virus (HAV) infection. Previous studies in Turkey showed that most residents had been infected with HAV by the second decade of life. In this study we aimed to detect the anti-HAV seroprevalence rate in Turkish military personnel and its relation with demographic properties. Materials and methods: Randomly selected 1049 military personnel were enrolled in the study. All were male and their average age was 24.97 ± 6.48 (Range: 20-50) years. A questionnaire about their demographic properties was administered to and informed consent forms were obtained from each subject. …
Comparison Of Clinical And Histopathologic Findings Of Pathergy Test With Disposable/Sharp And Nondisposable/Blunt Needles In Behcet´S Disease, Ayşe Serap Karadağ, Gülfer Akbay, Mehtap Aydin, Hesna Müzeyyen Astarci, Meral Ekşi̇oğlu
Comparison Of Clinical And Histopathologic Findings Of Pathergy Test With Disposable/Sharp And Nondisposable/Blunt Needles In Behcet´S Disease, Ayşe Serap Karadağ, Gülfer Akbay, Mehtap Aydin, Hesna Müzeyyen Astarci, Meral Ekşi̇oğlu
Turkish Journal of Medical Sciences
Aim: The aim of this study was to determine whether using blunt instead of sharp needles presented any advantage and whether the histopathological interpretation prevailed over the clinical interpretation. Materials and Methods: This study was performed on 60 Behçet´s disease (BD) patients and 20 control subjects. The pathergy test was applied to all subjects intradermally with sharp and blunt needles and the histopathology of each test result was studied. Results: In the active period of BD (40 patients), positive test results were obtained in 34 (85.0%) patients using blunt needles and in 13 (32.5%) using sharp needles (P = 0.0001). …
Comparison Of Gliclazide Treatment With Diet Therapy On Acute Phase Protein Levels In Patients With Type 2 Diabetes, Ramazan Memi̇şoğullari, Fati̇h Akçay, Abdurrahman Coşkun, Uğur Korkmaz
Comparison Of Gliclazide Treatment With Diet Therapy On Acute Phase Protein Levels In Patients With Type 2 Diabetes, Ramazan Memi̇şoğullari, Fati̇h Akçay, Abdurrahman Coşkun, Uğur Korkmaz
Turkish Journal of Medical Sciences
Aims: It is known that there is a relationship between diabetic complications and chronic inflammation characterized by alterations in circulating acute phase proteins. It has been emphasized that inflammation contributes to diabetic complications and that gliclazide -an antidiabetic sulfonylurea - decreases the development of such complications. In this study, we aimed to investigate whether gliclazide or diet treatment has an effect on serum levels of acute phase reactants, markers of inflammation. Materials and Methods: Fifty-six newly diagnosed patients with type 2 diabetes and 30 clinically healthy subjects were evaluated prospectively. Twenty-six patients were treated with proper diet and daily gliclazide …
Recurrent Breast Abscess Caused By Corynebacterium Amycolatum And Rewiev Of The Literature, İsmet Özaydin, Mustafa Yildirim, İdri̇s Şahi̇n, Sami̇ Doğan
Recurrent Breast Abscess Caused By Corynebacterium Amycolatum And Rewiev Of The Literature, İsmet Özaydin, Mustafa Yildirim, İdri̇s Şahi̇n, Sami̇ Doğan
Turkish Journal of Medical Sciences
Corynebacterium species are an uncommon cause of breast abscess, and Corynebacterium amycolatum is rarely described in the literature. In the present case, we report recurrent breast abscess caused by C. amycolatum in a 39-year-old patient with normal immune function. Pathological diagnosis was granulomatous mastitis. The patient was treated with incision and drainage and ampicillin-sulbactam treatment. To our knowledge, this is the second report of breast abscess caused by C. amycolatum.
Investigation (In Vivo And In Vitro) Of Booster Dose Vaccine Requirement For Long-Term Protection Against Hepatitis B Virus Infection, Onur Saygun, Can Polat Eyi̇gün, İsmai̇l Yaşar Avci, Üçler Kisa, Alaaddi̇n Pahsa
Investigation (In Vivo And In Vitro) Of Booster Dose Vaccine Requirement For Long-Term Protection Against Hepatitis B Virus Infection, Onur Saygun, Can Polat Eyi̇gün, İsmai̇l Yaşar Avci, Üçler Kisa, Alaaddi̇n Pahsa
Turkish Journal of Medical Sciences
Aim: Studies have shown that no booster dose was required at least 10 to 15 years after a primary vaccination for individuals who developed protective anti-hepatitis B surface (anti-HBs) antibodies. In this study, booster dose requirement for HBV after primary immunization was investigated. Materials and Methods: Seventeen individuals vaccinated previously were enrolled in the study. They had once developed a protective level of anti-HBs antibody after immunization and their anti-HBs titer had declined to an underprotective level. Twenty uninfected and unvaccinated healthy people were chosen as controls. Lymphoproliferative response to in-vitro stimulation with hepatitis B surface antigen (HBsAg) and anti-HBs …
The Epidemiology Of Microsporidias In Humans (Malatya Sample), Ülkü Karaman, Ni̇lgün Daldal, Meti̇n Atambay, Cemi̇l Çolak
The Epidemiology Of Microsporidias In Humans (Malatya Sample), Ülkü Karaman, Ni̇lgün Daldal, Meti̇n Atambay, Cemi̇l Çolak
Turkish Journal of Medical Sciences
Aim: Microsporidias, first isolated and defined in 1857, are obligate intracellular parasites observed in animal groups and especially invertebrates. Generally homosexual patients and patients who are HIV positive and immune suppressed constitute the participants of international studies about the epidemiology of microsporidias. No previous studies about the prevalence of the parasite in Turkey have been found in the literature. This study aimed to determine the epidemiology of microsporidias in and around Malatya. Materials and Methods: Feces samples (n: 2665) from patients who presented at İnönü University Medical Faculty policlinics in 2006 with some digestive system complaints and were referred to …
The Problem Of Antimicrobial Resistance In Nosocomial Medical And Surgical Intensive Care Units Infections In A University Hospital; A Two-Year Prospective Study, Şaban İnceci̇k, Neşe Saltoğlu, Akgün Yaman, İbrahi̇m Karayaylali, Mehmet Özalevli̇, Murat Gündüz, Refi̇k Burgut
The Problem Of Antimicrobial Resistance In Nosocomial Medical And Surgical Intensive Care Units Infections In A University Hospital; A Two-Year Prospective Study, Şaban İnceci̇k, Neşe Saltoğlu, Akgün Yaman, İbrahi̇m Karayaylali, Mehmet Özalevli̇, Murat Gündüz, Refi̇k Burgut
Turkish Journal of Medical Sciences
Aim: To determine the frequency of nosocomial infections (NIs) and the antimicrobial resistance of pathogens isolated from patients admitted to 4 intensive care units (ICUs) at a university hospital. Materials and Methods: The patients were prospectively followed over 2 years in medical, surgical, and reanimation ICUs. The isolates were collected from patients with NI determined by the Center for Diseases Control and Prevention criteria. The identification was performed and susceptibility to antibiotics was determined in an automated system Sceptor (Becton Dickinson) as described by the CCLS. Results: Among the 3962 patients in the ICUs, total NI incidence was 6.9%, with …
Disseminated Herpes Zoster Infection In A Patient With Lymphoma, Behi̇ce Kurtaran, Semra Paydaş, Aslihan Candevi̇r, Süheyla Kömür, Hasan Sali̇h Zeki̇ Aksu
Disseminated Herpes Zoster Infection In A Patient With Lymphoma, Behi̇ce Kurtaran, Semra Paydaş, Aslihan Candevi̇r, Süheyla Kömür, Hasan Sali̇h Zeki̇ Aksu
Turkish Journal of Medical Sciences
Immunosuppression facilitates varicella zoster virus (VZV) reactivation in immunocompromised patients. Atypical presentation such as disseminated disease of herpes zoster infection has been described in immunosuppressed patients. One of the best choices of therapy in herpes zoster infection is acyclovir, but long-term therapy may cause resistance to it. In this report a disseminated herpes zoster infection is described in a patient with T cell lymphoma after acyclovir/valacyclovir therapy. The infection was irresponsive to acyclovir and valacyclovir and we were unable to control the infection because it was not possible to obtain foscarnet and the patient died due to Staphylococcus epidermis sepsis.