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Green Production Of Metal Nanoparticles For Drug Delivery Applications, Nada Mostafa Aboeita
Green Production Of Metal Nanoparticles For Drug Delivery Applications, Nada Mostafa Aboeita
Theses and Dissertations
Marine algae are a rich source of biologically active compounds such as sulfated polysaccharides, lipids, proteins, carotenoids and polyphenols, that can be used in food, cosmetic, nutraceutical and pharmaceutical industries due to their antioxidant, anticancer, antibacterial, and anticoagulant activities. In the present study, ultrasound-assisted extraction was performed on the red algae Pterocladia capillacea. The extraction procedure was optimized to maximize yield and total carbohydrate content. The extract was shown to possess potent antioxidant activity and was successfully used as a reducing and capping agent in the green synthesis of copper nanoparticles. The synthesized copper nanoparticles were characterized by UV-spectroscopy, Fourier …
Evaluation Of The Cytotoxic Effect Of Salvia Triloba On Osteosarcoma (U2os) Cell Line, Rowan Bahaa El-Din Abd El-Bary
Evaluation Of The Cytotoxic Effect Of Salvia Triloba On Osteosarcoma (U2os) Cell Line, Rowan Bahaa El-Din Abd El-Bary
Theses and Dissertations
Despite the huge advancement in the field of cancer treatment, the conventionally used treatments still present significant challenges such as low effectiveness and adverse side effects. Thus, there is a critical need to continuously develop new, more effective and safe drugs against cancer. Herbal plants serve as a potential source for a wide variety of complex compounds with probable anticancer activity. The genus Salvia encompasses about 900 species. Salvia triloba, commonly known as Greek sage, is native to the Middle East and is inherently linked to local traditional medicine systems. It was recently shown to possess anti-proliferative activity against breast …
Elucidating The Role Of The High Aliphatic Glucosinolate ( Hag ) Genes In Pennycress ( Thlaspi Arvense L. ) Glucosinolate Production, Dalton Williams
Elucidating The Role Of The High Aliphatic Glucosinolate ( Hag ) Genes In Pennycress ( Thlaspi Arvense L. ) Glucosinolate Production, Dalton Williams
Theses and Dissertations
Pennycress (Thlaspi arvense L.) is a Brassica species being developed into an oilseed-producing winter cash cover crop. Similar to its relatives, rapeseed (Brassica napus L.) and camelina (Camelina sativa L.), pennycress seeds produce high levels of oil and protein (~34% oil and ~19% protein dry weight). For pennycress to be economically viable and environmentally sustainable as a crop, both the oil and seed meal must be utilized. Pennycress like other Brassicaceae, produces high levels of glucosinolates in the seed coat. Glucosinolates taste bitter and can be metabolized by the enzyme, myrosinase, into toxic isothiocyanates, nitriles, and epithionitriles. Seed meal containing …
Creating Identity In The Face Of The Other: A Levinian Reading Of Luis Vélez De Guevara's La Serrana De La Vera, Elizabeth Anne Jensen
Creating Identity In The Face Of The Other: A Levinian Reading Of Luis Vélez De Guevara's La Serrana De La Vera, Elizabeth Anne Jensen
Theses and Dissertations
Among the works of theater of the Spanish Golden Age which feature a mujer varonil, Luis Vélez de Guevara's play, La serrana de la Vera (1613), is particularly provocative. The intensity and ambiguity of the dual nature of its female protagonist, Gila, has been the subject of much recent scholarly investigation. The staging of the play lends itself to a Levinian reading, a new approach to this particular text and theater of the Golden Age in general. Emmanuel Levinas moves beyond metaphysics, phenomenology and intentionality to posit ethics as first philosophy. Levinas explains that the face of the Other is …
Public Punitiveness: The Intersection Of Racial Attitudes And Empathy, Arsala Aneeq Khan
Public Punitiveness: The Intersection Of Racial Attitudes And Empathy, Arsala Aneeq Khan
Theses and Dissertations
Public punitiveness has grown in recent decades and two components that help explain this rise are negative racial attitudes and empathy. For this thesis, a survey was passed out to 66 undergraduate criminal justice students at a mid-sized southern university. In order to better understand respondent relationship to punitiveness, a factor analysis was conducted that divided punitiveness into three scales. These scales were subsequently measured using three OLS regression analyses testing punitiveness with negative racial attitudes, empathy and control variables. The results showed no significant relationships between negative racial attitudes, empathy, and punitiveness. However, control variables such as age and …
Doped Carbonaceous Materials And Thin Films As Smart Materials For Pollutant Remediation And Electrocatalytic Applications, Bijay Paudel Chhetri
Doped Carbonaceous Materials And Thin Films As Smart Materials For Pollutant Remediation And Electrocatalytic Applications, Bijay Paudel Chhetri
Theses and Dissertations
In this dissertation, we focused on utilizing naturally abundant, low-cost, environmentally benign, and renewable carbon precursors to synthesize doped carbonaceous materials as they are of particular interest in the scientific research because of their characteristic physiochemical properties. Such renewable bio-polymer derived doped carbonaceous hold potential applications in fuel cells, pollutant remediation, and many others. Due to the growing interest in developing high performance electrode materials for energy storage devices like supercapacitors, the design of thin-fils electrodes that delivered high specific capacitance with long term stability is essential. In chapter 1, the dissertation discussed backgrounds in carbon-based materials, renewable biopolymers, fuel …
Cellulose-Based Doped Carbon Materials For Removal Of Nitrophenols From Water, Ambar Bahadur Rangu Magar
Cellulose-Based Doped Carbon Materials For Removal Of Nitrophenols From Water, Ambar Bahadur Rangu Magar
Theses and Dissertations
Nitrophenols (NPs) and their derivatives are highly toxic, mutagenic, and bio-refractory pollutants commonly present in natural water resources and industrial wastewater. Various types of materials and methods have been practiced removing the NPs from polluted water. In this research, we are focusing on synthesizing of inexpensive doped carbon-based materials using renewable and biodegradable polymers such as microcrystalline cellulose and nanocrystalline cellulose. Current work has been undertaken to develop doped carbon-based materials using a low-cost and straightforward method and characterized using different analytical techniques. The synthesized materials were used for the sustainable and efficient removal of NPs from an aqueous environment …
A Pedagogy Of Constraints: How Self-Imposed Limitations Influence Art-Making And Teaching, Emmalee Glauser Powell
A Pedagogy Of Constraints: How Self-Imposed Limitations Influence Art-Making And Teaching, Emmalee Glauser Powell
Theses and Dissertations
This study explores how self-imposed limitations affect anxieties about art-making and the art-making process. As a teacher, I was interested in how limitations affected student art-making. I used arts-based research methodology to explore spiritual and personal quandaries in my own life through the process of art-making. A consistent thread throughout this investigation was using the process of making art as a way to gain understanding about my own life and teaching. I was also able to create a culture of vulnerability and honesty in my classroom and help my students embrace themselves and their physical, emotional, and situational limitations through …
Synthesis Of Functionalized Streptococcus Pneumoniae Serotype 6a Di- And Tri- Saccharides, Brady Davis James
Synthesis Of Functionalized Streptococcus Pneumoniae Serotype 6a Di- And Tri- Saccharides, Brady Davis James
Theses and Dissertations
There is a rise in prevalence of antibiotic resistance in Streptococcus pneumoniae, and its FDA-approved vaccines often do not mount effective immune responses in children, the elderly, or the immunocompromised. One reason these vaccines are generally less effective is because they do not utilize T-cell help. T-cell help can be accessed when di-, tri-, or tetra-saccharides positioned inside major histocompatibility complex (MHC) II are presented to T-cell receptors as a target antigen. Pairing MHC II-antigen complexes with T-cell receptors enables development of B and T lymphocytes that are highly specific to these antigens, granting an increase in antibody affinity and …
The Crosstalk Between Cobra1 And Wnt/β-Catenin Signaling In Cervical Cancer, Omnia Mahmoud Abdelraheem
The Crosstalk Between Cobra1 And Wnt/β-Catenin Signaling In Cervical Cancer, Omnia Mahmoud Abdelraheem
Theses and Dissertations
The majority of cancer phenotypes, therapeutic resistance, and clinical prognosis are correlated to dysregulated transcriptional programs within cancer cells. Cofactor of BRCA1 (COBRA1), named also as NELF-B, is one of the principal components of the Negative Elongation Factor (NELF) complex. NELF complex negatively regulates the elongation of transcripts by halting RNA polymerase II at the proximal promoter. It also regulates the transcription of its target genes via interacting with other transcription factors like BRCA1 and AP-1. A previous study by our team showed that the silencing of COBRA1 led to a noted decrease in the steady-state mRNA levels of β-catenin …
On The Racialized Self-Production Of The Egyptian State: Hierarchical Structures Of Refugee Exclusion, Hend Ahmed Mohamed
On The Racialized Self-Production Of The Egyptian State: Hierarchical Structures Of Refugee Exclusion, Hend Ahmed Mohamed
Theses and Dissertations
This study aims to examine the ‘racialized self-production’ of the Egyptian state through the lens of its practices of exclusion against the Sudanese, Ethiopian, and Syrian refugee communities. The study provides an understanding of the Egyptian state’s practices of racialization and its production of a hierarchy of ‘whiteness’. This study argues that the Egyptian racialized self-production and hierarchy of ‘whiteness’ shape the extent and types of practices of exclusion exhibited against the aforementioned refugee communities. This thesis looks at how practices of statehood in Egypt are entrenched in racial hierarchies and ‘structures of whiteness’ and relatedly, the extent to which …
A Religious Space As A Place For Migrants In Cairo, Alexsa Macdowall
A Religious Space As A Place For Migrants In Cairo, Alexsa Macdowall
Theses and Dissertations
The focus of this study is an international, English speaking Anglican congregation that worships in Cairo, Egypt. Through participant observation and in-depth interviews, fifteen congregants of varying nationalities and backgrounds were interviewed in order to understand how the church is a place of meaning for them, as migrants. By this congregation being the focus of study, this thesis contributes to migration research by being a non-ethnic pathway of study, religion, and it contributes to research conducted in the Global South. Findings and observations are understood primarily through the theoretical framework of space and place provided by Yi-Fu Tuan. Place making …
Nitrate Transport In The Unsaturated Zone, Patience Bosompemaa
Nitrate Transport In The Unsaturated Zone, Patience Bosompemaa
Theses and Dissertations
Abundance of nitrate in the soil is a basic issue in agricultural land-use regions, causing eutrophication and pollution of water bodies. The study focuses on the role of a saturated buffer zone (SBZ) to remove nitrate from the groundwater resulting from agricultural activities. The study area is herbaceous SBZ located in central Illinois (40.614382ºN, -89.023542ºW), which lies between a stream and a farm located upgradient. The SBZ has been outfitted with an agricultural runoff treatment system that diverts tile drainage into the subsurface of the SBZ rather than discharging into the stream. Within the SBZ three experimental areas composed of …
On The Distribution Of Inter-Arrival Times Of 911 Emergency Responseprocess Events, Blake Cameron Moss
On The Distribution Of Inter-Arrival Times Of 911 Emergency Responseprocess Events, Blake Cameron Moss
Theses and Dissertations
The 911 emergency response process is a core component of the emergency services critical infrastructure sector in the United States. Modeling and simulation of a complex stochastic system like the 911 response process enables policy makers and stakeholders to better understand, identify, and mitigate the impact of attacks/disasters affecting the 911 system. Modeling the 911 response process as a series of queue sub-systems will enable analysis into how CI failures impact the different phases of the 911 response process. Before such a model can be constructed, the probability distributions of the inter-arrivals of events into these various sub-systems needs to …
The Zabaleen Of Egypt: Citizenship Of Exception In Cairo's Urban Sphere, Kathryn Vallis
The Zabaleen Of Egypt: Citizenship Of Exception In Cairo's Urban Sphere, Kathryn Vallis
Theses and Dissertations
This thesis examines the relationships between citizenship, space, and the state, using the Zabaleen community in Cairo as a lens of analysis. The thesis argues that citizenship is both an institution and a practice of exclusion. It explores the social, political, and economic exclusions that the Zabaleen experience due to their position in a state of exception.
Arterial Blood Flow At Rest And During Exercise With Blood Flow Restriction, Nicole Denney Tafuna'i
Arterial Blood Flow At Rest And During Exercise With Blood Flow Restriction, Nicole Denney Tafuna'i
Theses and Dissertations
PURPOSE: This study comparted arterial occlusion pressure (AOP) of the superficial femoral artery (SFA) between the dominant and nondominant legs and the relationship between blood flow and occlusion pressure at rest and during muscle contractions in males and females. METHODS: The AOP of the SFA was measured using Doppler ultrasound in the dominant and nondominant legs of 35 (16 males, 19 females) apparently healthy, normotensive young adults. Blood flow in the SFA was measured in the resting state (REST) and during plantar flexion exercise (EXC) at occlusion pressures ranging from 0% to 100% of AOP. ANOVA was used to compare …
Exploration Of First-Generation Student-Athlete Experiences At A Suburban Division Iii Institution, Mandy Jiang
Exploration Of First-Generation Student-Athlete Experiences At A Suburban Division Iii Institution, Mandy Jiang
Theses and Dissertations
The purpose of this phenomenological study is to explore the experiences of first-generation student-athletes (FGSA) on a college campus. One major goal of this study is to offer new discussion for first-generation student-athletes to increase awareness on this population in current literature. While there is research on first-generation students and collegiate student-athletes as separate identities, this specific population, combining both identities, has not been at the forefront of scholarly research (Oratagus & Merson, 2015). By expanding the current literature with evidence-based research, student affairs professionals and college athletic administrators can better enhance the experiences of first-generation student-athletes on their campuses. …
Prediction Of Drug-Drug Interaction Potential Using Machine Learning Approaches, Joseph Scavetta
Prediction Of Drug-Drug Interaction Potential Using Machine Learning Approaches, Joseph Scavetta
Theses and Dissertations
Drug discovery is a long, expensive, and complex, yet crucial process for the benefit of society. Selecting potential drug candidates requires an understanding of how well a compound will perform at its task, and more importantly, how safe the compound will act in patients. A key safety insight is understanding a molecule's potential for drug-drug interactions. The metabolism of many drugs is mediated by members of the cytochrome P450 superfamily, notably, the CYP3A4 enzyme. Inhibition of these enzymes can alter the bioavailability of other drugs, potentially increasing their levels to toxic amounts. Four models were developed to predict CYP3A4 inhibition: …
Geometric Extensions Of Neural Processes, Andrew Newberry Carr
Geometric Extensions Of Neural Processes, Andrew Newberry Carr
Theses and Dissertations
Neural Processes (NPs) are a class of regression models that learn a map from a set of input-output pairs to a distribution over functions. NPs are computationally tractable and provide a number of benefits over traditional nonlinear regression models. Despite these benefits, there are two main domains where NPs fail. This thesis is focused on presenting extensions of the Neural Process to these two areas. The first of these is the extension of Neural Processes graph and network data which we call Graph Neural Processes (GNP). A Graph Neural Process is defined as a Neural Process that operates on graph …
Effect Of Non-Muscle Myosin Ii Inhibition On Epigenetics During Oligodendrocyte Development, Amr Almaktari
Effect Of Non-Muscle Myosin Ii Inhibition On Epigenetics During Oligodendrocyte Development, Amr Almaktari
Theses and Dissertations
Non-Muscle Myosin II (NMII) is a mechanosensitive motor protein implicated in oligodendrocyte (OL) development. The inhibition of NMII is known to promote OL development and maturation. This project found that NMII inhibition does not affect oligodendrocyte development by altering their epigenetic profile.
The Role Of Perceived Heterosexism In Posttraumatic Stress Symptom Severity Among Trauma-Exposed Sexual Minority Individuals, Natalie M. Cereseto
The Role Of Perceived Heterosexism In Posttraumatic Stress Symptom Severity Among Trauma-Exposed Sexual Minority Individuals, Natalie M. Cereseto
Theses and Dissertations
This thesis employed structured posttraumatic stress disorder (PTSD) assessments, a micro-longitudinal 30-day daily diary assessment, and multilevel modeling to investigate the unique and interactive effects of traumatic stress and daily sexual minority-related discrimination on PTSD symptoms and negative affect in a diverse sample of 38 trauma-exposed SM individuals.
Presence And Degree Of Contrafreeloading In African Grey Parrots (Psittacus Erithacus), Gabriella E. Smith
Presence And Degree Of Contrafreeloading In African Grey Parrots (Psittacus Erithacus), Gabriella E. Smith
Theses and Dissertations
This study examined contrafreeloading—choosing a physical task to access food over free food—in two Grey parrots (Psittacus erithacus). Both birds contrafreeloaded for food of equal or higher value, but differed in which contrafreeloading task they preferred. Differences between the parrots are considered as individual preferences for self-reinforcing tasks.
The Collaborative Urban Resilience Banquet, Or @The_C_U_R_B, Candace B. Thompson
The Collaborative Urban Resilience Banquet, Or @The_C_U_R_B, Candace B. Thompson
Theses and Dissertations
The Collaborative Urban Resilience Banquet (The C.U.R.B.) is an interdisciplinary art project consisting of citizen science experiments, community events, and social media storytelling that collectively examine critical issues of environmental, social, and food-based justice as we face oncoming climate crisis. The project explores lessons learned about/with/from Brooklyn's feral edible plant and animal species, many of whom have long and complicated relationships with humanity. Artist Candace Thompson of The C.U.R.B. forages and processes these beings into food and medicine, and conducts DIY remediation experiments with them in an attempt to mitigate any contamination found therein. She shares her fndings via an …
Pvt1 Exon 9 A Regulator Of Claudin Expression In Triple Negative Breast Cancer, Fayola Levine
Pvt1 Exon 9 A Regulator Of Claudin Expression In Triple Negative Breast Cancer, Fayola Levine
Theses and Dissertations
Claudin low triple negative breast cancer (TNBC) has the worst clinical outcomes in comparison to other breast cancer subtypes. The underlying molecular mechanisms associated with the aberrant expression of claudins are not well understood. The transcript from PVT1 exon 9 is a regulator of claudin expression, and migration, in TNBC.
Mapping Ecological Futures: Toward A Cartography Of Climate Justice, Timothy C. Lau
Mapping Ecological Futures: Toward A Cartography Of Climate Justice, Timothy C. Lau
Theses and Dissertations
The concept of climate justice importantly reveals the uneven impacts of climate change. However, existing attempts at mapping climate justice are dominated by nation-state-based approaches, which fail to capture the sociospatial complexity of climate injustice. To address that gap, this thesis explores climate justice through the lens of critical cartography.
Interpersonal Emotion Regulation, Suicide Attempts, And Self-Injurious Behavior, Mariah Xu
Interpersonal Emotion Regulation, Suicide Attempts, And Self-Injurious Behavior, Mariah Xu
Theses and Dissertations
Emotion dysregulation and intense affect have been found to differentiate people who only think about suicide from people who attempt suicide, and social support is a protective factor against suicide attempts. Prior research has not conceptualized social influences on affective processes as a cohesive process in the development and evaluation of suicide risk. The current study investigates the role of interpersonal emotion regulation (IER), or how others manage or change individuals’ emotions, in both chronic and acute suicide risk. IER can contribute to chronic suicide risk by influencing intrapersonal emotion regulation long-term, and increasing acquired capability through dysregulated behaviors such …
Cytotoxic Analysis Of Old Drugs: New Drugs For Alzheimer’S Disease, Sebastian Yumiseba
Cytotoxic Analysis Of Old Drugs: New Drugs For Alzheimer’S Disease, Sebastian Yumiseba
Theses and Dissertations
Microglia are the resident immune cells of the CNS and constitute about 10% of all cells in the CNS. They have a vital role in Alzheimer’s pathogenesis as either cytotoxic or neuroprotective. Recent efforts are being put into repurposing drugs to target the microglia to treat Alzheimer’s disease.
Identity Development In Adolescent And Young Adult Cancer Survivors, Rachel M. Walsh
Identity Development In Adolescent And Young Adult Cancer Survivors, Rachel M. Walsh
Theses and Dissertations
The current study investigated identity development among adolescent and young adult cancer survivors. We examined the relationship between identity development with body image, self-esteem and self-perception. Results suggest that AYA survivors’ sense of self (how they perceive themselves, and how much they like themselves) is associated with their identity status.
Projections On Glass: Reconsidering Glass Pilgrim Vessels From Byzantine Jerusalem, Roxanne D. Jacobson
Projections On Glass: Reconsidering Glass Pilgrim Vessels From Byzantine Jerusalem, Roxanne D. Jacobson
Theses and Dissertations
Taking an object-orientated approach, this paper reconsiders a series of glass pilgrim vessels that survive from Byzantine Jerusalem and argues against the previous studies that focused solely on iconography to determine the vessels' function.
Beyond Movements: Senga Nengudi’S Art Within And Without Feminism, Postminimalism, And The Black Arts Movement, Tess Thackara
Beyond Movements: Senga Nengudi’S Art Within And Without Feminism, Postminimalism, And The Black Arts Movement, Tess Thackara
Theses and Dissertations
An examination of Senga Nengudi's relationship to Feminism, Postminimalism, and the Black Arts Movement. This thesis argues that, while her work overlapped with those three movements and tendencies, she ultimately expanded each of them to absorb greater sets of cultural references and formal criteria into their makeup.