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Stage-Structured Predator-Prey Interactions In A Warming World: A Case Study In Riverine Rock Pools, Andrew T. Davidson Jan 2023

Stage-Structured Predator-Prey Interactions In A Warming World: A Case Study In Riverine Rock Pools, Andrew T. Davidson

Theses and Dissertations

Warming can impact predator-prey interactions through a variety of mechanisms. For example, warming can both alter the rate at which predators consume prey and the rate prey develop through vulnerable life stages. Thus, the overall effect of warming on consumer-resource interactions will depend upon the strength and asymmetry of warming effects on predator and prey performance. Here, we describe the consequences of these asymmetrical responses to temperature by first developing a simple stage-structured modeling framework, then applying that framework to predation of American rock pool mosquito larvae, Aedes atropalpus, by several common predators in riverine rock pools. We then …


Interactions Between Hiv And Opioids On Antiretroviral Accumulation, The Blood Brain Barrier, And The Inflammatory Response In The Brain., Kara Rademeyer Jan 2023

Interactions Between Hiv And Opioids On Antiretroviral Accumulation, The Blood Brain Barrier, And The Inflammatory Response In The Brain., Kara Rademeyer

Theses and Dissertations

The complex mechanisms related to HIV infection, neurodegeneration, and chronic neuroinflammation collectively describe neuroHIV (Hauser et al. 2007; Chang et al. 2014; Smith et al. 2014). Specifically, opioid abuse, poor penetration of antiretroviral (ARV) drugs, chronic inflammation and neuronal injury/degeneration are all implicated in neuroHIV (Fantuzzi et al. 2003; Letendre et al. 2004; Verani et al. 2005; Duncan and Sattentau 2011; Hong and Banks 2015; Simoes and Justino 2015; Olivier et al. 2018; Murphy et al. 2019; Osborne et al. 2020). For the first time, we demonstrate that morphine, fentanyl, and methadone in vivo alter the brain accumulation of ARVs, …


Buckets In A Deep Well: Essays About Shakespeare’S History Play Characters And An Original Drama, Brian C. Bassett Jan 2023

Buckets In A Deep Well: Essays About Shakespeare’S History Play Characters And An Original Drama, Brian C. Bassett

Theses and Dissertations

Buckets in a Deep Well is a set of essays that examines various characters portrayed in Shakespeare’s history plays, as well as parallel figures in 20th and 21st century works. Each essay primarily focuses on a single character’s response to a power structure: Richard Gloucester to the Tudor England of his audience in Richard III; Richard Nixon’s campaign-produced version of himself to 20th century American democracy in “Checkers;” Falstaff to organized society in Henry IV, Part 1; Marlo Stanfield to the drug economy of early 2000’s Baltimore in The Wire; the Duke of York to the disrupted monarchy of The …


Climate, Physiology, And Distributions: The Role Of Thermal Physiology In Biological Invasions, Sean D. Powers Jan 2023

Climate, Physiology, And Distributions: The Role Of Thermal Physiology In Biological Invasions, Sean D. Powers

Theses and Dissertations

Climate is a primary factor influencing species range dynamics, particularly for ectotherms whose body temperature is closely tied to the surrounding conditions. While range shifts of ectotherms are attributed to climate warming, the mechanism driving these shifts are not well understood. Studies in macrophysiology demonstrate that the interaction of climate with thermal physiology plays a key role in determining large-scale spatial and temporal patterns for many temperature-sensitive physiological traits. This work has revealed a clear relationship between thermal tolerance breadth and range size. However, more recent analyses of this relationship demonstrate that thermal tolerance breadth only provides a partial explanation …


Diversity, Phylogenetics And Life Cycles Of Diplostomoidean (Digenea: Diplostomoidea) Of The Upper Midwest, Jakson Martens Jan 2023

Diversity, Phylogenetics And Life Cycles Of Diplostomoidean (Digenea: Diplostomoidea) Of The Upper Midwest, Jakson Martens

Theses and Dissertations

The superfamily Diplostomoidea Poirier, 1886 consists of a diverse, globally distributed group of parasitic flatworms parasitic as adults in reptiles, birds, mammals, and very rarely, fish. The superfamily Diplostomoidea has a tumultuous history full of genus synonymizations and resurrections. Currently, the superfamily consists of 39 genera parasitizing primarily piscivorous animals as adults to include birds, reptiles, and mammals. This group of parasitic worms remains a highly active area of research and has recently undergone several major systematic changes including the abandonment of a subfamily-based system. Additionally, the influx of data entries in GenBank has lead to confusing nomenclature and misidentifications …


Assessing Options For Reducing Greenhouse Gas Emissions And Increasing Energy Production From Municipal Solid Waste Utilizing Epa Models, Marcus Richburg Jan 2023

Assessing Options For Reducing Greenhouse Gas Emissions And Increasing Energy Production From Municipal Solid Waste Utilizing Epa Models, Marcus Richburg

Theses and Dissertations

The population of the planet surpassed the 8-billion-person mark in 2022, and the increase in population has brought about an increase in waste, both household and commercial. The municipal solid waste that is created is primarily stored in landfills, particularly in the United States. These landfills release methane and carbon dioxide into the atmosphere, creating what is known as anthropogenic emissions, due to their being caused by man-made issues. These two primary gases, along with others, make up greenhouse gases, and their reduction is key to potentially reducing or even reversing the greenhouse effect. Total municipal solid waste generation in …


Spectral Classification Of Eight Stars In Open Cluster Ngc 457, Anthony Braden Jan 2023

Spectral Classification Of Eight Stars In Open Cluster Ngc 457, Anthony Braden

Theses and Dissertations

This project aimed to perform spectral analysis and classification on eight target stars in the open star cluster NGC 457 with the University of North Dakota Space Studies Observatory. Selected targets came from a search in the SIMBAD database with a radius of two arcseconds around the cluster's center. The eight brightest stars in the visual spectrum were chosen, which did not have luminosity classifications. Six observing sessions were performed over two years to maximize data quality, given the unpredictability of terrestrial observations. Spectral data were acquired in both high- and low-resolution mode. The spectral data were calibrated and analyzed …


Mitigating Global Temperature Change Through Industrial Sector Improvements: A Case Study In Automotive Manufacturing, Alec Joseph Ernst Jan 2023

Mitigating Global Temperature Change Through Industrial Sector Improvements: A Case Study In Automotive Manufacturing, Alec Joseph Ernst

Theses and Dissertations

Manufacturing is an integral part of our country’s flow of products and people and a top contributor to carbon emissions, promoting global temperature rise. During processing, toxic substances are emitted across the value chain. These emissions account for nearly 25% of all greenhouse gas emissions in the United States and the World. Until 2023, an accessible pathway for manufacturing companies to transition to net-zero emissions hasn’t been made readily available. The current research was conducted to determine if reducing carbon emissions in manufacturing facilities through efficiency improvements, process optimization, and technology advancements can mitigate global temperature change.This quantitative, mixed-method approach …


Remote Sensing Of Chlorophyll-A In Small And Medium Lakes In The Minnesota Northern Forest Ecoregion, Jacob Alan Moll Jan 2023

Remote Sensing Of Chlorophyll-A In Small And Medium Lakes In The Minnesota Northern Forest Ecoregion, Jacob Alan Moll

Theses and Dissertations

Algae blooms have become increasingly common in many bodies of water and are occurring in more and more new locations. Past methods have relied on in-situ sampling to determine Chl-a concentrations and can be time and cost intensive. With the use of NASA’s Harmonized Landsat imagery existing methods of index calculation can be implemented, with the added benefit of an increase in temporal resolution. This increase in temporal resolution allows for more detailed spatial and temporal analysis such as hot spot analysis. Harmonized Landsat imagery was proven sufficient in spatial and temporal resolution for detection of Chl-a in small and …


When The Verdict Is Not So Black And White: Juror Perceptions And Judgments Of Biracial Defendants, Mariah Sorby Jan 2023

When The Verdict Is Not So Black And White: Juror Perceptions And Judgments Of Biracial Defendants, Mariah Sorby

Theses and Dissertations

Racial disparities are a persistent issue within the United States criminal justice system. Past research has investigated how defendant characteristics (e.g., race and phenotype) and juror attitudes and beliefs (e.g., stereotypes and prejudice) influence mock juror case judgments and perceptions. This literature has primarily investigated outcomes for monoracial defendants. However, there is a significant need for research investigating outcomes of multiracial defendants. The purpose of this project was to investigate the influence of phenotype, crime stereotypes, and juror attitudes on case judgments and perceptions of Black-White Biracial defendants compared to White and Black defendants. Participants were randomly assigned to view …


Neuromodulatory Mechanisms Of Neuropeptides In The Amygdala, Cody Adam Boyle Jan 2023

Neuromodulatory Mechanisms Of Neuropeptides In The Amygdala, Cody Adam Boyle

Theses and Dissertations

The amygdala is a limbic structure critical for emotional processing as well as roles in learning and memory. Disruption of the normal activity of the amygdala has been implicated in several disorders including phobia disorders, anxiety-like disorders, and substance abuse. The function of the amygdala and its role in various disorders is directly related to its underlying cellular activity. The amygdala is both a cortical- and striatal-like structure containing mainly glutamatergic and GABAergic neurons, respectively. This dissertation has three aims related to the neuropeptide modulation of these cell types in the basolateral (BLA) and central amygdala (CeA). The first aim …


Environmental Toxicity Of Isoxazoline Drugs On Non-Target Species, Haley M. Cooper Jan 2023

Environmental Toxicity Of Isoxazoline Drugs On Non-Target Species, Haley M. Cooper

Theses and Dissertations

Lyme disease affects tens of thousands of people every year in the United States, causing serious illness and even death. It is caused by the bacterium, Borrelia burgdorferi, through infected black-legged tick bites. The range of these ticks is expanding, causing Lyme disease cases to increase. Considerable effort has been put toward research and eradication of Lyme disease, with limited success. Isoxazoline drugs, commonly used to prevent flea and tick infestations in dogs, could be dispatched in the field to keep black-legged ticks off the reservoir host of Lyme disease, the White-footed mouse. Little research has been done on …


Family Of Origin Influence On Workplace Dynamics: A Qualitative Study, Megan E. Malave Jan 2023

Family Of Origin Influence On Workplace Dynamics: A Qualitative Study, Megan E. Malave

Theses and Dissertations

This study delves into the intricate interplay between Family of Origin influences and the professional practice of Organizational Development (OD) practitioners. Rooted in the recognition that Family of Origin experiences significantly shape individual perspectives and behaviors, this research investigates how OD practitioners leverage this understanding to navigate complex workplace dynamics. Grounded in the Use of Self framework, which emphasizes intentional utilization of one's complete being for enhanced effectiveness, this study explores the multifaceted connections between Family of Origin dynamics and common relational aspects such as leadership, influence, power, conflict, and belonging. Through qualitative analysis of OD practitioners' perspectives, the study …


A Global Perspective On Mindfulness-Based Interventions In Schools, Rebecca H. Laff Jan 2023

A Global Perspective On Mindfulness-Based Interventions In Schools, Rebecca H. Laff

Theses and Dissertations

The practice of mindfulness, which originated in ancient Buddhist philosophy, has gained popularity in secular society through the work of Western researcher Jon Kabat-Zinn. Kabat-Zinn's focus on using mindfulness to help chronically ill patients cope with stress soon expanded into non-clinical areas, including education. Mindfulness-based interventions (MBIs) adapted from Kabat-Zinn’s work, have been utilized in schools since 2005, but there has been a lack of systematic research on the effectiveness of MBIs in classroom settings globally. To address this gap, this critical interpretive synthesis (CIS) study conducted a comprehensive literature review of quantitative and qualitative studies from around the world …


Living In Ilopango’S Shadow: Using A Figurative Analysis Of Grave Goods Excavated From Ciudad Nuevo Cuscatlán In El Salvador To Investigate The Community’S Relationship To The Ilopango Volcano, Kari O'Doran Jan 2023

Living In Ilopango’S Shadow: Using A Figurative Analysis Of Grave Goods Excavated From Ciudad Nuevo Cuscatlán In El Salvador To Investigate The Community’S Relationship To The Ilopango Volcano, Kari O'Doran

Theses and Dissertations

The purpose of this thesis is to determine what can be learned about the people living near the Ilopango Volcano during the Classic period of Mesoamerican history by conducting a figurative analysis of the living subjects depicted on the ceramics and figurines excavated from the area, to determine what, if any, relationship the people there had with the volcano. I examine the frontier Mesoamerican village of Ciudad Nuevo Cuscatlán by analyzing grave goods found in the mortuary burials located in the area and determining the meaning of the figural subjects on each using established diagnostic elements from experts in the …


Lived Experiences Of College-Educated Black Women: Contextualizing Gendered Racial Health Disparities, Christiana L. Johnson Jan 2023

Lived Experiences Of College-Educated Black Women: Contextualizing Gendered Racial Health Disparities, Christiana L. Johnson

Theses and Dissertations

Black women are disproportionately affected by gendered racial health disparities. Public health research that seeks to unearth the root cause of these gendered racial health disparities is insufficient. More recently, researchers have turned their attention to structural inequities and their influence on the lived experiences of Black women. This study contributes to this body of work by using a theoretical concept derived from intersectionality⎯structural gendered racism⎯to identify key upstream social factors that shape nulliparous, college-educated Black women's lived experience and childbearing desires. Semi-structured, individual interviews were conducted with nulliparous, college-educated Black women (n=30), ages 25 to 35, living in the …


Risk And Resilience: An Exploration Of Adverse Childhood Experiences, Protective Factors, And Internalizing Symptoms In Black Youth, Irene A. Jacobs Jan 2023

Risk And Resilience: An Exploration Of Adverse Childhood Experiences, Protective Factors, And Internalizing Symptoms In Black Youth, Irene A. Jacobs

Theses and Dissertations

The study examines mechanisms of risk and resilience that influence the psychological well-being of Black youth. Previous literature has established a link between adverse childhood experiences (ACEs) and mental health outcomes in youth (Kerker et al., 2015; Thakur et al., 2020). A substantial amount of the ACEs literature solely focuses on risk factors (e.g., mental impairment, low SES, health risk behaviors) for poor outcomes associated with ACEs. Despite Black youth experiencing high rates of ACEs (Liu et al., 2019), the ACEs literature examining mechanisms of their resilience is sparse (Meeker et al., 2021). Given the state of the ACEs literature, …


Probing The Porphyromonas Gingivalis Nitrosative Stress Response Network, Alexandra Galina Jan 2023

Probing The Porphyromonas Gingivalis Nitrosative Stress Response Network, Alexandra Galina

Theses and Dissertations

Objective: To persist in the oral cavity, the perio-pathogen Porphyromonas gingivalis must have an efficient nitrosative stress response mechanism. To better understand how P. gingivalis responds to nitrite (NO2-) we must determine what genes are involved in the nitrosative stress response network.

Methods: Through genomic screening, a list of genes was generated that were hypothesized to be part of the nitrosative stress response network and believed to be involved in nitrate/nitrite metabolism or redox state of the cells. Protein coding regions were replaced with the ermF sequence by allelic exchange mutagenesis. 15 mutants were created …


Sustaining Breaths For Restorative Rest: A Preliminary Evaluation Of Sleep, Mental Health, And Cognitive Function Following Hypoglossal Nerve Stimulation For Obstructive Sleep Apnea, Elliottnell Perez Jan 2023

Sustaining Breaths For Restorative Rest: A Preliminary Evaluation Of Sleep, Mental Health, And Cognitive Function Following Hypoglossal Nerve Stimulation For Obstructive Sleep Apnea, Elliottnell Perez

Theses and Dissertations

Introduction: Obstructive sleep apnea (OSA) is a sleep-related breathing disorder that produces repetitive obstruction or collapse of the upper airway. Positive airway pressure (PAP) therapy is the gold standard treatment for OSA. Hypoglossal nerve stimulation (HNS) is considered an alternative treatment for patients who are unable to tolerate PAP therapy. The purpose of the study was to examine sleep, mental health, and cognitive health outcomes before and after HNS to determine its viability as an alternative treatment.

Methods: The study utilized a single-group, pretest-posttest design. Objective and subjective sleep was measured using actigraphy, sleep diary, and questionnaires. Objective and subjective …


Machine Learning Models To Automate Radiotherapy Structure Name Standardization, Priyankar Bose Jan 2023

Machine Learning Models To Automate Radiotherapy Structure Name Standardization, Priyankar Bose

Theses and Dissertations

Structure name standardization is a critical problem in Radiotherapy planning systems to correctly identify the various Organs-at-Risk, Planning Target Volumes and `Other' organs for monitoring present and future medications. Physicians often label anatomical structure sets in Digital Imaging and Communications in Medicine (DICOM) images with nonstandard random names. Hence, the standardization of these names for the Organs at Risk (OARs), Planning Target Volumes (PTVs), and `Other' organs is a vital problem. Prior works considered traditional machine learning approaches on structure sets with moderate success. We compare both traditional methods and deep neural network-based approaches on the multimodal vision-language prostate cancer …


Community On Campus: Examining The Impact Of Campus Climate, Belonging, And Flourishing On Bystander Behavior Among Diverse University Students, Amelia Liadis Jan 2023

Community On Campus: Examining The Impact Of Campus Climate, Belonging, And Flourishing On Bystander Behavior Among Diverse University Students, Amelia Liadis

Theses and Dissertations

This exploratory, nonexperimental study aimed to investigate the relationships among diverse undergraduate and graduate students’ perceived campus climate, flourishing, and university belonging on bystander intentions and bystander behaviors during the COVID-19 pandemic. The study’s theoretical framework combined the Theory of Planned Behavior and feminist theory, and examined intersectionality through an Identity Risk Index. Data used in the current study were originally collected as part of an institutional Healthy Minds Survey, on health behaviors of college students; responses from n = 171 of the randomly selected participants were used in the current study’s analyses. The majority of participants indicated at least …


Supporting Students Who Are Deafblind To Increase Their Access To The General Education Curriculum Through Trained Interveners: A Mixed Methods Study, Ira Padhye Jan 2023

Supporting Students Who Are Deafblind To Increase Their Access To The General Education Curriculum Through Trained Interveners: A Mixed Methods Study, Ira Padhye

Theses and Dissertations

The purpose of this mixed-methods research study was to identify the educational trends of children and young adults who are deafblind and identify strategies to improve the outcomes through interviews of nationally qualified interveners who have received training in deafblind specific strategies. Secondary data from the 2017-2021 National Center on Deafblindness and interview transcripts were used for data analysis and then integrated to identify the supports students who are deafblind should access. Trends in age of identification, primary eligibility category, school settings and access to state standardized assessments showed a plateau and displayed no significant improvement in educational outcomes. Nationally …


Layer-By-Layer Assembled Particles For Non-Invasive Inhaled Therapeutic Delivery To The Lungs, Gautam Chauhan Jan 2023

Layer-By-Layer Assembled Particles For Non-Invasive Inhaled Therapeutic Delivery To The Lungs, Gautam Chauhan

Theses and Dissertations

Inhalation route is frequently used to administer drugs for managing respiratory diseases with high pulmonary drug concentration and low systemic side effects. But due to the complex lung structure and defense mechanism, only a small fraction of the dose can reach the lung. There have been several advances in strategies to overcome these challenges and achieve localized delivery to the lung. In this study, we are expanding the scope for lung delivery using a multifunctional delivery system called layer-by-layer (LbL) assembled particles. These are core particles coated with polyelectrolytes multilayer which have a wide range of properties and can be …


Controlled Release Matrix Tablet Formulation Of Verapamil Hydrochloride, Shapali Anil Bagde Jan 2023

Controlled Release Matrix Tablet Formulation Of Verapamil Hydrochloride, Shapali Anil Bagde

Theses and Dissertations

Three major challenges face the formulation of a successful hydrophilic polymer matrix. The objective of the formulation research is to concentrate on these issues. The first challenge is to maintain consistent drug release from these matrix systems; swelling and polymer dissolution occur when these systems are placed in a dissolution medium. A gel layer forms as the polymer swells, increasing the matrix tablet thickness. Polymer dissolution starts with chain disentanglement over time causing the matrix tablet thickness to gradually decrease until it undergoes complete dissolution. In the release of water-soluble drugs through a hydrophilic matrix, the thickness of the gel …


Ccl2 Suppression In Lewis Lung Carcinoma Model Enhances Host Survival And Immune Response In The Tumor Microenvironment, Nivedita Biswas Jan 2023

Ccl2 Suppression In Lewis Lung Carcinoma Model Enhances Host Survival And Immune Response In The Tumor Microenvironment, Nivedita Biswas

Theses and Dissertations

CCL2, a chemokine also referred to as monocyte chemoattractant protein 1 (MCP-1) and small inducible cytokine A, is chemotactic for monocytes. CCL2-induced recruitment of CCR2+Ly6C(hi) monocytes increases vascular permeability CCR2+ endothelium aiding the escape and migration of tumor cells. CCL2 is produced by cancers of varied immunogenicity and augments tumor proliferation and metastasis. Elevated CCL2 expression by tumor cells is linked to poor prognosis.We have previously shown that two bacterially derived superantigens, Staphylococcal enterotoxin G and I (SEG/SEI) stimulate large numbers of T cells in an antigen-independent fashion and promote enhanced survival in the poorly immunogenic B16-F10 melanoma model. Conversely, …


Dyslexia And The Need For General Education Teacher Training, Sheeresa S. Begay Jan 2023

Dyslexia And The Need For General Education Teacher Training, Sheeresa S. Begay

Theses and Dissertations

General education teachers are expected to provide instruction to and promote learning in all students within a general education classroom per state and federal mandates. These mandates ensure students with disabilities like dyslexia are given access to a general education classroom, curriculum, and materials, and provided with support through an Individualized Education Program (IEP) or 504 Plan. However, general education teacher training and professional development programs have often been ineffectual in preparing general education teachers for delivering instruction to and promoting learning in individuals with dyslexia. As a result, many general education teachers are unprepared for supporting students with dyslexia …


Tribo-Mechanical Behavior Of Cold Rolled And Directed Energy Deposited Niti Alloy For Space Applications, Hyunsuk Choi Jan 2023

Tribo-Mechanical Behavior Of Cold Rolled And Directed Energy Deposited Niti Alloy For Space Applications, Hyunsuk Choi

Theses and Dissertations

The manufacturing industry is constantly looking for ways to improve processes and reduce costs while maintaining or enhancing material properties. Nickel-Titanium (NiTi) alloy, also known as Nitinol, has unique properties such as shape memory and superelasticity, which make it a valuable material for various applications in the medical and aerospace industries. However, due to its high toughness, strength, and ductility, NiTi is difficult to form and machine, leading to severe tool wear and high cutting energy. Conventional manufacturing processes have limitations in producing complex or porous designs, restricting NiTi's potential applications. Additive manufacturing techniques have been explored as a way …


Soil Bacteria Composition In Conservation Reserve Program Grasslands Of The Great Plains, Lydia M. Kantonen Jan 2023

Soil Bacteria Composition In Conservation Reserve Program Grasslands Of The Great Plains, Lydia M. Kantonen

Theses and Dissertations

The Conservation Reserve Program (CRP) is a grassland restoration program that allows landowners to remove degraded land from crop production, seed it with a perennial seed mixture, and leave it fallow for the remainder of the contract, which usually ranges from 10-15 years. While some ecosystem functions quickly improve upon CRP enrollment, soil organic carbon is slow to return to pre-agricultural levels. One explanation is that particulate organic matter left by litter takes several years to degrade even with a full bacteria community. Alternatively, it is possible that different chemical components of organic matter require different bacteria communities for full …


Natural Fractals And Facial Emotion Recognition, Nathaniel Joseph Pagel Jan 2023

Natural Fractals And Facial Emotion Recognition, Nathaniel Joseph Pagel

Theses and Dissertations

The psychological benefits that come from visually processing natural imagery have been widely studied. The components of natural imagery that provoke positive responses are not fully understood. This study uses a mixed design approach to identify if the acute exposure to statistical fractal imagery, of both a high-range or mid-range complexity, affects cognitive workload, physiological arousal, and gaze patterns in the recognition and identification of emotions through facial expressions. Participants were undergraduate students fulfilling a partial course requirement (N = 87). Eye-tracking metrics were used to compare exposure to fractal complexities. Participants were randomly assigned to either be exposed to …


Childhood Adversity And The Millon Clinical Multiaxial Inventory, Fourth Edition (Mcmi-Iv), Jenna Marie Wolff Jan 2023

Childhood Adversity And The Millon Clinical Multiaxial Inventory, Fourth Edition (Mcmi-Iv), Jenna Marie Wolff

Theses and Dissertations

The Millon Clinical Multiaxial Inventory, 4th edition (MCMI-IV; Millon et al., 2015) is a reliable and valid personality assessment based on Theodore Millon’s biosocial learning theory of personality. Millon’s theory evolved to include 15 personality constructs that vary in adaptive and maladaptive response patterns. In his most recent book (Millon, 2011), he presented hypotheses about biological and environmental factors that contribute to development of each personality construct. Many of these hypotheses specify particular adversities in childhood that differentially contribute to each construct. This study is the first to evaluate Millon’s hypotheses about how childhood adversities may contribute to development of …