Digital Commons Network^™

National And Local Antibiotic Prescribing Trends And Prescribing Appropriateness In Older Adults, Fawaz M. Alotaibi

Theses and Dissertations

Background: Antibiotic overuse/misuse has been documented in several reports to increase the risk of Clostridioides difficile (C.diff) infection and antibiotic resistance. The older adult population is more prone to use antibiotic medications than any other age group due to decreased immune function, use of urinary catheters, ventilation during hospitalization and other factors. Antibiotic resistance and C.diff are major public health problems. However, studies examining the trends of antibiotic use and the association between the antibiotic use and negative health outcomes among older adults in the outpatient and emergency department settings are limited.

Objectives: The main objectives of this …

The Efficacy Of A Group Visual Art Bereavement Intervention With Older Adults, Rachel E. Weiskittle

Theses and Dissertations

Research on expressive art interventions for bereavement has burgeoned in recent years. Studies have supported their effectiveness in facilitating participants’ adjustment to loss (e.g., Rosner, Kruse, & Hagl, 2010; Uttley, 2015) and have revealed the frequency with which they are clinically implemented (Thompson & Neimeyer, 2014). Clinicians and recipients of expressive art interventions advocate for their helpfulness in grief processing (e.g., Gamino, 2015). Publications have highlighted particular visual art modules that facilitate adaptive adjustment to loss by providing avenues for self-expression, meaning making and continuing bonds with the deceased (Neimeyer, 2016), but few studies have quantitatively investigated whether they improve …

The Effect Of Change In Medi-Cal Dental Coverage On Dental Care Utilization Among Medi-Cal Beneficiaries, Min H. Zhang

Theses and Dissertations

One of the most important factors in accessing dental care is having dental insurance. For people with low incomes, Medicaid is the main source of health insurance. Medi-Cal is California’s Medicaid program. Adult dental services were mostly eliminated in Medi-Cal in 2009 due to the economic downturn and partially restored in 2014. The objective of this study is to evaluate the effect of change in Medi-Cal dental coverage, specifically the partial restoration of adult dental coverage in 2014, on dental care utilization among Medi-Cal beneficiaries. The partial restoration significantly increased the utilization rates in dental clinics from 2014 to 2017 …

Older Adult Caregivers’ Lived Experiences With Debilitated Chronically Ill Relatives In A Rural Southern County, Nancy J. Dameron

Theses and Dissertations

By 2030, the last of the baby boomer generation will reach the age of 65, which will expand the older adult population to more than 70 million in the United States. Based on the inflated numbers of the older adult population and the noted decreased birth rate in the younger population, fewer health-care providers will be available to teach, prepare, train, and assist caregivers in the ongoing care of their ill relatives.

The problem investigated in the study involved the present upsurge of the older adult population living longer and contributing to a shortage of health-care providers for older adults. …

Acoustic Correlates Of Aging And Familial Relationship, Samantha Michelle Taylor

Theses and Dissertations

The purpose of this study was to examine the potential differences in selected acoustic measures of speech as a function of age, across sexes, and between families. The data used in this study were previously collected for a larger project on voice production at the University of Utah. Participants included 169 individuals, 79 men and 90 women, from 18 Utah families, ranging in age from 17 to 87 years. All participants had no history of articulation disorders, stroke or active neurologic disease, or severe-profound hearing loss. Participants were recorded reading two passages aloud in a sound booth. These two passages …

A Graph Theoretical Analysis Of Functional Brain Networks Related To Memory And Healthy Aging, Ty Alvin Bodily

Theses and Dissertations

The cognitive decline associated with healthy aging begins in early adulthood and is important to understand as a precursor of and relative to mild cognitive impairment and Alzheimer disease. Anatomical atrophy, functional compensation, and network reorganization have been observed in populations of older adults. In the current study, we examine functional network correlates of memory performance on the Wechsler Memory Scale IV and the Mnemonic Discrimination Task (MST). We report a lack of association between global graph theory metrics and age or memory performance. In addition, we observed a positive association between lure discrimination scores from the MST and right …

A Dual Examination Of Learning Through Pedagogical Training And Alzheimer's Disease Pathology, Donielle Breanna Hutchinson

Theses and Dissertations

Active learning strategies are important for facilitating deep learning that may be carried throughout life, but which is still finding its way into the college setting. Educators are not often trained in effective learning practices, which reduces the cognitive and proficiency gains of their students. By providing such guidance in the formative years of a teacher’s training, we hypothesize that the learning environment will be greatly enriched and enhanced. On the opposite end of the spectrum of life and cognition, the plague of dementia also warrants examination. Alzheimer’s disease (AD), an incurable neurodegenerative disorder progressing from the medial temporal lobe, …

Passive Hallux Adduction Decreases Blood Flow To Plantar Fascia, Julia Lorene Dunbar

Theses and Dissertations

Purpose: Due to the vital role that blood flow plays in maintaining tissue health, compromised blood flow can prevent effective tissue healing. An adducted hallux, as often seen inside a narrow shoe, may put passive tension on the abductor hallucis, consequently compressing the lateral plantar artery (LPA) into the calcaneus and thus restricting blood flow. The purpose of this study was to compare blood flow within the LPA before and after passive hallux adduction (PHA). Methods: Forty-five healthy volunteers (20 female, 25 male; age = 24.8 ± 6.8 yr; height = 1.7 ± 0.1 m; weight = 73.4 ± 13.5 …

Application Of The Entropy Concept To Thermodynamics And Life Sciences: Evolution Parallels Thermodynamics, Cellulose Hydrolysis Thermodynamics, And Ordered And Disordered Vacancies Thermodynamics, Marko Popovic

Theses and Dissertations

Entropy, first introduced in thermodynamics, is used in a wide range of fields. Chapter 1 discusses some important theoretical and practical aspects of entropy: what is entropy, is it subjective or objective, and how to properly apply it to living organisms. Chapter 2 presents applications of entropy to evolution. Chapter 3 shows how cellulosic biofuel production can be improved. Chapter 4 shows how lattice vacancies influence the thermodynamic properties of materials. To determine the nature of thermodynamic entropy, Chapters 1 and 2 describe the roots, the conceptual history of entropy, as well as its path of development and application. From …

Effect Of Curcumin Supplementation On Exercise-Induced Oxidative Stress, Inflammation, And Muscle Damage, Steven Allen Basham

Theses and Dissertations

Oxidative stress (OS) and inflammation can be detrimental to exercise performance. Antioxidants such as curcumin are shown to reduce exercise-induced OS, inflammation, muscle damage, and soreness. The purpose of this study was to examine the effect of curcumin on biomarker markers of OS (MDA, TAC), inflammation (TNF-á), muscle damage (CK) and soreness. Participants performed an exercise-induced muscle damage protocol. Before and after supplementation, subjects were randomly assigned to curcumin (1.5 g/day) or placebo for 28 days. Blood was sampled immediately before and after exercise, as well as 60 min, 24, and 48 h after exercise. No significant differences were observed …

Out Of The Shell: Exploring The Phagocytic Capabilities Of The B Cell And Isolated Lymphoid Follicle-Lie Structures In The Red-Eared Slider, Trachemys Scripta, Marc A. Ashford Jr.

Theses and Dissertations

Management of immunity is crucial for survival in all living organisms. While there is a large amount of research for established model organisms, such as the mouse model, much less is known about reptiles. When compared to immunity in mammals, we discover many differences such as susceptibility to certain pathogens, alteration of immune processes due to environmental temperature, the total absence of certain lymphoid organs contained in mammals, among many others. Despite this, the reptile has shown in many studies that they are worthy systems to study immunity in an evolutionary perspective and recent studies may show that they may …

Effects Of Divided Attention On Speech In Parkinson's Disease, Melissa Inkley

Theses and Dissertations

The effects of divided attention on speech in Parkinson's disease (PD) have been studied for a variety of tasks in recent years. Much of the previous research studied gait patterns while participants concurrently performed another task. There have been few studies regarding the effects of divided attention on speech in individuals with PD. The ability to communicate effectively relies in part on an appropriate rate of speech, vocal intensity, and fundamental frequency control. This study included 27 participants: 8 with PD, 12 neurologically healthy older (HO) adults, and 7 healthy younger (HY) adults. Each participant was given a list of …

Adults With Cystic Fibrosis: Self-Management And Health Outcomes, Amanda Rose Lambie

Theses and Dissertations

This dissertation is comprised of three manuscripts for publication reporting on adults living with cystic fibrosis, self-management behaviors and health outcomes. Chapter I explores what is known about adults living with cystic fibrosis (CF) and the factors impacting their self-management, including the complexities of a health maintenance regime required for survival while integrating and balancing the realities of adulthood. The review of literature provides direction for future research and implications for adult-focused CF studies. Chapter II is a manuscript describing the characteristics of prognostic survival models utilized in adult CF research and provides an overview of their development, validation, predictive …

Ageism Among Healthcare Professionals: The Influence Of Personal Aging Anxiety, Job Role, And Work Setting On Attitudes Toward Older Patients, Jennifer L. K. Inker

Theses and Dissertations

Older adults make up a significant and increasing proportion of the U.S. population and are frequent users of healthcare services. Ageism in healthcare, driven by an incomplete and narrowly biomedical perspective on aging, has been linked to various problematic outcomes for older patients, including under- and over-treatment. The purpose of this study was to use the theory of relational ageism to explore the relationship between personal aging anxiety among healthcare professionals and their attitudes to older patients, considering the potentially moderating factors of job role and work setting. Using convenience sampling, clinical healthcare professionals working for a mid-sized, regional healthcare …

Novel Insights Into The Contribution Of Cellular Senescence To Cancer Therapy: Reversibility, Dormancy And Senolysis., Tareq Saleh

Theses and Dissertations

Cellular senescence a specialized form of growth arrest that contributes to the pathogenesis of several aging-related disorders including cancer. While by definition tumor cells are considered immortalized, they can undergo senescence when exposed to conventional and targeted cancer therapy. Therapy-Induced Senescence (TIS) represents a fundamental response to therapy and impacts its outcomes. However, TIS has been considered a positive therapeutic goal since senescent tumor cells are expected to enter a state of permanent growth abrogation. In this work we examined the hypothesis that a subpopulation of senescent cells can re-acquire proliferative potential after a state of senescent dormancy, indicating that …

Senior Food Environments: Predicting Low Food Access And Developing Interventions For Seniors In Nonmetropolitan Counties, Joshua J. Turner

Theses and Dissertations

The continued growth of the nation’s older adult population will bring many societal challenges. One of these challenges deals with meeting this population’s basic needs. Among the most crucial basic needs in older adulthood is proper nutrition, which is heavily impacted by one’s ability to access adequate amounts of healthy foods. Extensive research has been conducted on low food access among diverse populations, but opportunities remain to expand upon this research by concentrating on the food access challenges facing the older adult population. The current study had a twoold purpose. First, this study aimed to serve a basic academic purpose …

Social Capital And Hospital Readmission Of Older Adults, Sheryl Emmerling

Theses and Dissertations

This dissertation is comprised of three manuscripts exploring the concept of social capital and hospital readmission of older adults. The first manuscript provides a review of the literature evaluating studies that measure the relationship between social capital and health, healthy behaviors, and access to and utilization of healthcare resources. Further research focusing on testing various types of individual social capital and their relationship to key outcomes including hospital readmission is needed.

The second manuscript is a description of the Social Capital and Health Framework that can serve as an outline for assisting nurses and other healthcare providers to consider older …

An Exploratory Study Of Formal And Informal Help-Seeking Behavior Among Married Individuals Who Are Thinking About Divorce, David Michael Simpson

Theses and Dissertations

Previous research on marital help-seeking has often focused on formal approaches such as marital therapy or relationship education and there is a greater need to understand married individual's informal help-seeking behaviors. This study explores both formal and informal help-seeking behavior using a national sample of 745 participants who have thought about divorce within the past 6-months. Findings indicate these participants more often engaged in informal help-seeking approaches to repair their marriage. Of those sampled, only 25% engaged in marital therapy together and only 9% engaged in a marriage strengthening class while over 30% read a relationship themed self-help book or …

Reduced Immune Investment With Energy Stress: Evidence From A Mouse Model And Human Studies, Alaina L. Schneider

Theses and Dissertations

During periods of energy stress, animals will prioritize and allocate energy from non-essential to essential tasks. Using a mouse model and published human data, we found that during periods of energy stress, energy is allocated away from immune function, and is prioritized for physical activity usage.

Co-Localization Patterns Of Aquaporin-4 With Amyloid Beta And Cd68 In Alzheimer's Disease And Cerebrovascular Disease, Anthony Bryan Crum

Theses and Dissertations

Aquaporin-4 (AQP4) is a key component in maintaining proper glymphatic flow. In recent years, the glymphatic system has been discovered and approached as a major factor in amyloid plaque clearance in Alzheimer's disease. This study examines the depolarization of AQP4 from the astrocytic endfeet and subsequent co-localization with amyloid plaques in the hippocampus and subiculum. Results show a significant pattern of co-localization in advanced Alzheimer's disease, as well as increases in AQP4 in cerebrovascular disease. This pattern shows AQP4 should be approached as a promising therapeutic area in future research.

The Effects Of Income And Ethnicity On Health Outcomes Of Mexican Immigrant And Anglo Women, Andrea M. Debarros

Theses and Dissertations

The Hispanic Paradox is the finding that Hispanic immigrants living in the United States have better health than Anglo Americans despite being socioeconomically disadvantaged (Crespo et al., 1996; Stern et al., 1999; Sundquist et al., 1999; Dixon et al, 2000; Lariscy et al., 2015; Overton et al., 2015; Thomson et al., 2013). The literature surrounding the Hispanic Paradox has studied these effects primarily in Mexican-American Immigrant populations (Sundquist et al., 1999; Dixon et al, 2000; Lariscy et al.); however, additional research has found similar findings for various other Hispanic countries such as Cuba and Puerto Rico (Abraido-Lanza, A F. et …

Current Patterns Of Ownership And Usage Of Mobile Technology In Older Adults, Karen E. Cottle

Theses and Dissertations

The older generation is growing at a rate surpassed only by the speed at which mobile technology is advancing. Technology has become so ubiquitous in daily life, that most older people have done their best to adopt it. The purpose of this study was to explore the older adult (>50 yrs.) learner's everyday approach to and regard for mobile technology. Paper surveys were distributed by hand to four geographically diverse audiences. Each audience was composed of a minimum of 20 adult learners of each gender across three age groups, accounting for 160 individual older adults in all. Returned survey …

Social Withdrawal And Psychological Well-Being In Later Life: Does Marital Status Matter?, Melanie Mei Serrao

Theses and Dissertations

Personality researchers have described dispositional traits to typically show stability over the life course and yet one such trait, shyness, has rarely been examined in later life. Shyness as a global trait has been linked negatively to multiple psychological indices of childhood well-being, including loneliness. Despite the fact that older adults may be already at risk for experiencing heightened loneliness, regret, or decreased fulfillment, research has not assessed these experiences in relation to personality in later life. In recent years, withdrawal research has begun to move past shyness as a global trait to examine the motivations behind socially withdrawn behavior. …

A Mixed Methods Study Of Online Course Facilitators' Perceptions Of Mobile Technology, Design, And Tpack Affordances, Helen Louise Teague

Theses and Dissertations

The increase in mobile technology options for students in post-secondary, continuing education influences how instructors design and implement courses, specifically online courses (Sözcü, İpek, & Kınay, 2016). Much of the current research addresses technological, pedagogical, and content knowledge (TPaCK), course design, and/or mobile technology as separate topics. There is limited research addressing the combination of TPaCK, design, and mobile technology from the course instructors’ perspective. The mixed methods study addressed design for online, mobile learning with a new layer of the TPaCK instructional framework in three phases. Phase 1 involved a pilot study of a survey that measured TPaCK, lesson …

Healthcare Leaders Under The Age Of 40: Successful Strategies And Practices For Leading Healthcare Organizations, Rizalyn Reynaldo

Theses and Dissertations

As millennials and young adults under the age of 40 become the growing majority, it is critical to understand their leadership profile, the workplace challenges they face, and their strategies for overcoming obstacles as young leaders. Specifically, in healthcare, the rapidly changing industry presents internal and external environmental challenges that must be handled in the most professional and proficient manner to be an effective leader. As such, the purpose of this study is to gather best strategies and practices that healthcare leaders under the age of 40 can adopt for their respective organizations. There are 4 research questions that address …

Understanding Over-The-Counter Medication Use And Decision-Making Among Community-Dwelling Us Older Adults: A Mixed-Methods Approach, Yoshita Paliwal

Theses and Dissertations

Introduction

Older adults are regular consumers of over-the-counter (OTC) medications. OTC medications are generally considered safe, and convenient to use without requiring a prescription. However, the safety of an OTC medication and the final health outcome depends in part upon consumers’ perceptions, beliefs, and their decision-making about OTC medication use. The main objectives of this study were: 1) to examine the prevalence and characteristics of OTC medication use among community-dwelling US older adults (65 years and older), 2) to explore older adults’ knowledge, attitudes, beliefs and experiences about OTC medications, and 3) to elicit the OTC medication decision-making process in …

The Impact Of Perceived Mental Illness Stigma On Caregivers’ Desire To Relinquish Care, Tyler R. Corson

Theses and Dissertations

Caregiving can be stressful, and older adults’ health and well-being may be impacted by the roles and responsibilities they assume as caregivers for persons with serious mental illness (SMI). This study is the first to apply the Stress Process Model of Caregiving (SPM) in an attempt to understand how mental illness stigma influences caregiver outcomes, specifically their desire to relinquish care. The intent of this study was to call attention to care relinquishment as an under-studied stress process outcome and to explore stress factors, with a focus on mental illness stigma, that contribute to SMI caregivers’ desire to relinquish care. …

Gomds - Grumpy Old Men Doing Shakespeare; The Comedy Of Errors As Metaphor For Life, Aging, And Building Community, Elizabeth B. Pedersen

Theses and Dissertations

This thesis explores the process of building community over time, through collaboration, to rehearse and produce a portable production of Shakespeare's The Comedy of Errors, looking at the elements of time, trust and age with an ensemble of ten men, all actors over the age of 55. The building of trust over time was vital to the production process and the actors had the time to embody their roles and the language of the play. We look at the questions “why this play,” “why all men?” and “why theatre?” and investigate the physical nature of the play and its …

Parental Experience-Based Change: Positive And Negative Changes In Monitoring, Expectations, Nurturing, And Discipline, Joseph S. Rand

Theses and Dissertations

This study sought to create a measure of parent's perceptions of parental experience-based change (PEBC), or parents' perceptions of the changes they make to their parenting of secondborn children as a result of experiences with firstborn children. The measure assessed PEBC in the domains of monitoring, expectations, nurturing and discipline. Participants were 401 mothers or fathers of 2 or 3 adolescent children. Factor analyses revealed an 8 factor solution that assessed increasing and decreasing in each of the 4 domains. Criterion validity was evaluated using regression analyses to examine the relationships between each factor and parenting outcomes thought to be …

A Horticultural Therapy Program For The Elderly: Effects On Cognition, Quality Of Life, And Loneliness, Mariah Ruth Baird

Theses and Dissertations

Previous studies suggest there are numerous benefits of horticultural therapy programs. The current study explored the benefits of a horticultural therapy program with elderly populations at two facilities in Bowling Green, Kentucky. Fifteen participants attended a 2-hour session on horticulture techniques once a week for four weeks. Using a pretest to posttest study design, changes in participants’ cognition, quality of life, and loneliness were assessed. The pretest was administered verbally by the researcher before the first session and the posttest, including a series of questions about satisfaction with the program, was administered after the last session. Items on each assessment …