Digital Commons Network^™

Reichenbachia, Imperial Edition: Rediscovering Frederick Sander’S Late-Victorian Masterpiece Of Botanical Art, Erica Borey

Theses and Dissertations

This thesis project examines the history, provenance, and contemporary treatment of a rare Imperial Edition of Frederick Sander’s print collection Reichenbachia, Orchids Illustrated and Described, a high-quality orchid compendium dating to the late-nineteenth century. A local philanthropist loaned the Imperial Edition Reichenbachia, number 86 of 100 to Lewis Ginter Botanical Garden in 2011 on a long-term basis as a promised donation. Research into the origins of this collection involves several disparate historical topics, including the Victorian period of “orchid mania,” imperialist business practices, and chromolithographic printmaking. Discussion of the transition of this collection into a museum art collection covers its …

Hybrid Pet/Mri Nanoparticle Development And Multi-Modal Imaging, David Hoffman

Theses and Dissertations

The development of hybrid PET/MRI imaging systems needs to be paralleled with the development of a hybrid intrinsic PET/MRI probes. The aim of this work was to develop and validate a novel radio-superparamagnetic nanoparticle (r-SPNP) for hybrid PET/MRI imaging. This was achieved with the synthesis of superparamagnetic iron oxide nanoparticles (SPIONs) that intrinsically incorporated 59Fe and manganese iron oxide nanoparticles (MIONs) that intrinsically incorporated 52Mn. Both [59Fe]-SPIONs and [52Mn]-MIONs were produced through thermal decomposition synthesis. The physiochemical characteristics of the r-SPNPs were assessed with TEM, DLS, and zeta-potential measurements, as well as in imaging phantom studies. The [59Fe]-SPIONs were evaluated …

On Relay Node Placement Problem For Survivable Wireless Sensor Networks, Changyong Jung

Theses and Dissertations

Wireless sensor networks are widely applied to many fields such as animal habitat monitoring, air traffic control, and health monitoring. One of the current problems with wireless sensor networks is the ability to overcome communication failures due to hardware failure, distributing sensors in an uneven geographic area, or unexpected obstacles between sensors. One common solution to overcome this problem is to place a minimum number of relay nodes among sensors so that the communication among sensors is guaranteed. This is called Relay Node Placement Problem (RNP). This problem has been proved as NP-hard for a simple connected graph. Therefore, many …

Maternal Monitoring And Maternal Psychological Well-Being: Important Components In Treating Conduct Disorder, Benjamin Rosen

Theses and Dissertations

Conduct disorder is characterized by behaviors that take a large toll on the individuals, families, and communities afflicted. Thus, improving treatment effectiveness should be a high priority. Currently, common intervention programs do not address parental depression, even though it has been linked to adolescent conduct disorder behaviors in some studies. The current study assessed whether the relation between maternal depression and adolescent conduct disorder behaviors is mediated by another factor which has been linked to conduct disorder behaviors, maternal monitoring. Results did not support the hypothesized mediated association, but did show significant individual associations for both maternal depression and maternal …

Regulation Of Satiety Quiescence: Cyclic Gmp, Tgf Beta, And The Asi Neuron, Thomas Gallagher

Theses and Dissertations

The worm Caenorhabditis elegans is a well-studied model organism in numerous aspects of its biology. This small free living nematode has less than 1,000 cells, but shows clear conservation in both signaling and behavior to mammals in aspects of appetite control. This is of importance to humans, where failure of appetite control is a major factor in the unprecedented obesity epidemic that we see today. In general, worm behavior reflects its internal nutritional state and the availability and quality of food. Specifically, worms show a behavioral state that mimics aspects of the mammalian behavioral satiety sequence, which has been termed …

The Effects Of Isolation On Endemic Cozumel Island Rodents: A Test Of The Island Rule, Brittany Marie Nuttall

Theses and Dissertations

Island isolation can cause changes in body size, cranial characteristics, and genetic variation in mammals. We use geometric morphometrics to test skull and mandible shape and size change across three species of endemic Cozumel Island rodents in order to test the “island rule” of larger size in isolated rodents. We also sequenced the D-Loop and cytochrome b region of the mitochondrial genome and tested for differences in genetic variation between island and mainland groups, as well as population structure and gene flow in order to assess the effect of island isolation on these three rodents. We found that the three …

Application Of Next-Generation Transcriptomic Tools For Non-Model Organisms: Gene Discovery And Marker Developmentwithin Plecoptera (Insecta), Nicholas Gregory Davis

Theses and Dissertations

Phylogenetic research on non-model organisms has been hindered by limited marker availability. Next generation sequencing techniques are eliminating that barrier. Using Illumina sequencing technology, Trinity assembly software, custom Perl reciprocal BLAST scripts, and Primer3 primer prediction software, we produced and analyzed 7 Plecopteran transcriptomes, representing 7 of the 16 total families, in an attempt to identify and develop conserved orthologous genetic markers. The transcriptomes were used to reconstruct a gene content phylogeny using a simple distance matrix generated from reciprocal blastn data. By producing and filtering a reciprocal blast network we identified and aligned over 450 putative orthologs. Out of …

Population Genetic Structure Of Bromus Tectorum In The American Desert Southwest, Desiree Rochelle Eldon

Theses and Dissertations

Following its introduction to North America in the late nineteenth century, Bromus tectorum L., an inbreeding invasive winter annual grass, has become dominant on millions of hectares of sagebrush steppe habitat throughout Intermountain Western North America. It appears that within the last 30-40 years, B. tectorum has expanded its range southward into the Mojave Desert and also into more climatically extreme salt desert environments. Previous research using microsatellite markers and experimental studies has suggested that lineages found in desert habitats are genetically distinct from those found in the sagebrush-steppe habitat and possess suites of traits that pre-adapt them to these …

Habitat Selection By Two K-Selected Species: An Application To Bison And Sage Grouse, Joshua Taft Kaze

Theses and Dissertations

Population growth for species with long lifespans and low reproductive rates (i.e., K-selected species) is influenced primarily by both survival of adult females and survival of young. Because survival of adults and young is influenced by habitat quality and resource availability, it is important for managers to understand factors that influence habitat selection during the period of reproduction. My thesis contains two chapters addressing this issue for K-selected species in Utah. Chapter one evaluates habitat selection of greater sage-grouse (Centrocercusurophasianus) on Diamond Mountain during the critical nesting and brood-rearing period. Chapter two address selection of birth sites by bison (Bison …

Exploring Post-Fire Recovery Of Biocrusts And Desert Ecosystem Services, Jason R. Bahr

Theses and Dissertations

Biocrusts and the ecosystem services they provide are becoming more susceptible to fire as exotic annual grass invasions facilitate the spread of desert wildfires. Further, precipitation patterns across the western United States are predicted to change over the next century, and have the potential to dramatically influence fire regimes and the recovery of burned biocrusts. Despite these changes to desert fire and precipitation cycles, our understanding of post-fire biocrust recovery is limited, especially regarding the first two years after fire. To investigate biocrust recovery, we created burn manipulations (i.e., unburned and burned) and tracked crust form and function over two …

Importance Of Placement Depth In Evaluating Soil Nitrogen, Phosphorus, And Sulfur Using Ion Exchange Resin Capsules In Semi-Arid, Low Fertility Soils, Rachel Lynn Buck

Theses and Dissertations

Ion exchange resin capsules provide a possible alternative to conventional soil testing procedures. Previous studies with semi-arid, low fertility soils observed poor relationships with poorly mobile nutrients such as phosphorus (P). We propose that placement depth may improve those relationships. Our objective was to (1) determine if placement depth could improve resin capsule estimation of the bioavailability of nitrogen (N), P, and sulfur (S) and (2) to determine if resin capsules can effectively estimate S availability in semi-arid, low fertility soils. Field sites were established in Rush and Skull Valleys, Utah on loam and sandy loam soils, respectively. Fertilizer was …

Involvement Of Ampk And Ap-1 Biochemical Pathways In Il-6 Regulation Of Steroidogenic Enzymes In The Adrenal Cortex, Matharage Shenali De Silva

Theses and Dissertations

The adrenal cortex is a crucial endocrine gland in the mammalian stress response. In chronic inflammatory stress, cortisol is elevated whereas adrenal androgens are decreased. Furthermore, ACTH levels have poor correlation with the plasma cortisol in these conditions, thus suggesting that other factors are driving the stress response during chronic inflammatory stress. Interleukin-6 (IL-6), a cytokine which is released during chronic inflammatory stress, is assumed to be one such factor. Thus the biochemical pathways by which IL-6 increases cortisol release from the zona fasciculata (ZF), and decreases adrenal androgen release from the zona reticularis (ZR) were investigated. Since IL-6 activates …

Ferritin-Based Photo-Oxidation Of Biomass For Nanoparticle Synthesis, Bioremediation, And Hydrogen Evolution, Oscar Petrucci

Theses and Dissertations

The cell is the basic unit of all living organisms. It is an amazing machine capable of self-replicating, growing, and synthesizing and shuttling thousands of compounds. To perform all of these activities the cell needs energy. The original source of energy for all living beings is the Sun. The energy of the sun is collected by the autotrophs (mostly plants) through photosynthesis and stored in the chemical bonds of carbohydrates and lipids through carboxylic acid intermediates; animals use these compounds to obtain the energy for their cells. Most of the energy extracted by the cell comes from the citric acid …

Utah Red Raspberry Jam: The Effects Of Formulation, Heating, And Time On Color, Flavor, Texture, And Antioxidant Capacity, Jennifer Leigh Chase

Theses and Dissertations

The amount and type of antioxidants present in raspberries is dependent upon cultivar, ripeness, and growing conditions. Previous research on raspberry jam has reported some color, antioxidant, and flavor loss after processing and storage, though it is unknown to what extent similar changes will occur in raspberries grown in Utah. Sugar concentration and heating temperature as well as storage time were evaluated in an effort to maximize color retention, flavor, antioxidant content, shelf life, and consumer acceptance of Utah-grown raspberry jam. Four types of jams were processed in two batches each: low-sugar (40-42 Brix) and typical sugar (65-68 Brix) at …

Documenting Tensions In Communities: Three Films By Eduardo Coutinho, Ryan James Norris

Theses and Dissertations

This project analyzes three documentaries that explore the inherent tensions and difficulties in building a sense of community in three different settings in Rio de Janeiro. The documentaries Boca de Lixo (1993), Santo forte (1999), and Edifí­cio Master (2002) by Eduardo Coutinho present an in-depth look at the tensions inherent in developing communal identity based on vocation in Boca de Lixo, religion in Santo forte, and location in Edifício Master. Through these documentaries, Eduardo Coutinho presents the difficulties faced by different groups of people in Brazil as they explore the development of a sense of community. Boca de Lixo endeavors …

Endocannabinoid-Dependent Long-Term Depression Of Ventral Tegmental Area Gaba Neurons, Jared Mark Weed

Theses and Dissertations

GABA neurons in the ventral tegmental area of the midbrain are important components in the brain's reward circuit. Long term changes in this circuit occur through the process of synaptic plasticity. It has been shown that high frequency stimulation, as well as treatment with endocannabinoids, can cause GABA neurons in the ventral tegmental area to undergo long term depression, a form of synaptic plasticity that decreases excitability of cells. The present study elaborates on the mechanism whereby high frequency stimulation can result in long term depression of ventral tegmental area GABA neurons. Using the whole cell patch clamp technique in …

Reading And Listening To Music Increase Resting Energy Expenditure During Indirect Calorimetry In Healthy Adults , Blaire Snell

Theses and Dissertations

The Academy of Nutrition and Dietetics has developed an evidence analysis library (EAL) for Nutrition and Dietetics professionals. The EAL is updated by members through workgroups consisting of experts in their fields, most often in response to unanswered questions. One such question is: what kinds of activities can be done during the rest period of an indirect calorimetry test in a healthy population? The objective of our study was to determine if listening to self-selected relaxing music or reading on an electronic device or a magazine effects resting energy expenditure (REE) as measured by an indirect calorimetry test in a …

Investigation Into The Effects Of Pegylation On The Thermodynamic Stability Of The Ww Domain, Sam S. Matthews

Theses and Dissertations

The covalent attachment of poly(ethylene glycol) (PEG) to a protein surface (known as PEGylation), has been demonstrated to increase the serum half-life of therapeutic proteins by reducing kidney clearance and immunogenicity and by protecting against proteolysis. Theses beneficial effects could be further enhanced if PEGylation consistently increased protein conformational stability (i.e. the difference in free energy between the folded and unfolded states). However, the effects of PEGylation on protein conformational stability are unpredictable; PEGylation has been reported to increase, decrease, or have no effect on the conformational stability of medicinal proteins.This thesis details the results of two studies aimed at …

Regulation Of The Myostatin Protein In Overload-Induced Hypertrophied Rat Skeletal Muscle, Paige Abriel Affleck

Theses and Dissertations

Myostatin (GDF-8) is the chief chalone in skeletal muscle and negatively controls adult skeletal muscle growth. The role of myostatin during overload-induced hypertrophy of adult muscle is unclear. We tested the hypothesis that overloaded adult rodent skeletal muscle would result in reduced myostatin protein levels. Overload-induced hypertrophy was accomplished by unilateral tenotomy of the gastrocnemius tendon in male adult Sprague-Dawley rats followed by a two-week period of compensatory overload of the plantaris and soleus muscles. Western blot analysis was performed to evaluate changes in active, latent and precursor myostatin protein levels. Significant hypertrophy was noted in the plantaris (494 ± …

Going The Distance: Themes Of The Hero In Disney's Hercules, Amy Elizabeth Burchfield

Theses and Dissertations

Disney's Hercules is an apt modern reception of the ancient mythology of Herakles, acknowledging ancient and modern sources surrounding three types of classical hero: the archetypal hero, influenced by the ideas of Joseph Campbell; the Pan-Hellenic hero, distilled from ancient Greek exempla of heroism from epic and other genres of ancient literature; and the tragic hero, inspired by the heroic criteria presented in Aristotle's Poetics. By adapting these heroic types from their traditional ancient source myths, Disney's Hercules produces a new, contemporary definition of heroism—one informed by modern, Western family values. This adaptation renews the power of the myth of …

Aerodynamic Performance And Particle Image Velocimetery Of Piezo Actuated Biomimetic Manduca Sexta Engineered Wings Towards The Design And Application Of A Flapping Wing Flight Vehicle, Anthony M. Deluca

Theses and Dissertations

Considerable research and investigation has been conducted on the aerodynamic performance, and the predominate flow physics of the Manduca sexta size of biomimetically designed and fabricated wings as part of the AFIT FWMAV design project. Despite a burgeoning interest and research into the diverse field of flapping wing flight and biomimicry, the aerodynamics of flapping wing flight remains a nebulous field of science with considerable variance into the theoretical abstractions surrounding aerodynamic mechanisms responsible for aerial performance. Traditional FWMAV flight models assume a form of a quasi-steady approximation of wing aerodynamics based on an infinite wing element model (BEM). An …

Anesthetic Considerations For Phantom Limb Pain, Robert B. Kari

Theses and Dissertations

Title: Anesthetic Considerations for Phantom Limb Pain

Background: Phantom limb pain (PLP) is a phenomenon where pain develops or is perceived in a body part that has been removed. With the prevalence of peripheral vascular disease secondary to diabetes, amputation rates are expected to increase in the next decade. Chronic pain syndromes such as phantom limb pain are difficult to manage and treat

Purpose: The purpose of this project is to detennine if preemptive analgesia for limb amputation is effective in the prevention of PLP

Process: A comprehensive review of the literature was perfonned using multiple …

Habitat Selection And Nesting Ecology Of Snowy Plover In The Great Basin, Kristen Sue Ellis

Theses and Dissertations

Snowy plovers (Charadrius nivosus) are small, ground-nesting shorebirds that are a species of conservation concern throughout North America. Despite increased efforts to understand factors contributing to the decline of snowy plover, little is known about habitat selection and breeding ecology of snowy plover for the large population found in the Great Basin. We tested hypotheses concerning the occupancy and nesting success of snowy plover. First, we identified factors influencing snowy plover nest survival at Great Salt Lake, Utah. We hypothesized that snowy plover would demonstrate differences in nest survival rates across years due to differences in habitat characteristics, predator abundance, …

Spectral Analysis Of Nonstationary Heart Rate Of Neonates Receiving Therapeutic Hypothermia Treatment, Tareq Al-Shargabi

Theses and Dissertations

We studied Heart Rate Variability (HRV) evolution during therapeutic hypothermia in newborns with hypoxic ischemic encephalopathy (HIE) using spectral analysis. We hypothesized that HRV measures are predictive of neurological outcome in babies with HIE. Non-stationarity in the data causes inaccurate quantification of the spectral power. A modification was proposed to power spectral analysis approach to mitigate the effect of non-stationarity. The modified and the standard approaches were applied to cardiac beat-to-beat intervals of newborns receiving hypothermia treatment. The performance of the approaches in distinguishing the RRi dynamics of two groups of newborns was assessed using area under the receiver operating …

Enigmatic Allegory, Sara Virginia Kinsey

Theses and Dissertations

My artwork is autobiographical and shaped by my experiences. Collectively, it serves as a visual journal expressing a range of emotions honoring meaningful people, portraying important places, and commemorating significant events in my life. My art documents the progression from turmoil, despair, and isolation to growth, recovery, and gratitude. I utilize a recurring set of subjective symbols which hold personal significance. These symbols, which include robots, eggs, chairs, shoes, and trash cans, help me create narratives and visual continuity across my body of work. I purposefully omit some information to mask the entirety of the story being told. Typically, these …

Differential Effects Of Short-Chain Fatty Acids On Motility Of Guinea Pig Proximal And Distal Colon, Norman Hurst

Theses and Dissertations

NTRODUCTION: Colonic bacteria produce short-chain fatty acids (SCFAs) by fermentation of dietary carbohydrates and fiber. The production of SCFAs is greatest in proximal colon where propulsion is likely to be highly dependent on chemical/nutrient stimuli. Unabsorbed SCFAs entering the distal colon are likely to modify peristalsis initiated by fecal pellet-induced distension. AIM: To determine the effect of individual SCFAs on propulsive contractions in guinea pig proximal colon and on pellet propulsion in distal colon. METHODS: Proximal colon was excised, cannulated and placed in Krebs buffer in an organ bath. After equilibration, the colon was distended with 1ml of Krebs buffer …

"Dae Scotsmen Dream O 'Lectric Leids?" Robert Crawford's Cyborg Scotland, Alexander Burke

Theses and Dissertations

This thesis applies a Cybernetic interpretation to a selection of poetry by the Scottish Informationist poet Robert Crawford, drawn mostly from two collections: A Scottish Assembly (1990) and Sharawaggi: Poems in Scots (1990). Crawford is contextualized by observing the poetic influences of Robert Burns, John Davidson, and Hugh MacDiarmid, as well as the philosophical influence of George Elder Davie’s The Democratic Intellect. This paper argues that, in response to the Two Cultures hypothesis put forth by C. P. Snow and the widely-held belief that Scotland is irrevocably fractured, the shifting boundaries of the many disparate Scottish cultures are mediated by …

Variation And Modulation Of Micrornas In Prostate Cancer And Biological Fluids, Sarah Seashols

Theses and Dissertations

Prostate cancer is the second-most diagnosed and fatal carcinoma for males in the United States, and better diagnostic markers and potential therapies are needed. microRNAs are small, single-stranded RNA molecules that affect protein expression at the translational level, and dysregulation can dramatically affect cell metabolism. Comparison of 736 microRNA expression levels between the poorly metastatic SV40T immortalized prostate epithelial cell line P69 to its highly tumorigenic and metastatic subline M12 identified 231 miRs that were overexpressed and 150 miRs that showed loss of expression in the M12 cell line. Further evaluation of fourteen identified miRs was accomplished using other prostate …

The Pseudo-Rigid-Body Model For Fast, Accurate, Non-Linear Elasticity, Anthony R. Hall

Theses and Dissertations

We introduce to computer graphics the Pseudo-Rigid-Body Mechanism (PRBM) and the chain algorithm from mechanical engineering, with a unified tutorial from disparate source materials. The PRBM has been used successfully to simplify the simulation of non-linearly elastic beams, using deflections of an analogous spring and rigid-body linkage. It offers computational efficiency as well as an automatic parameterization in terms of physically measurable, intuitive inputs which fit naturally into existing animation work flows for character articulation. The chain algorithm is a technique for simulating the deflection of complicated elastic bodies in terms of straight elastic elements, which has recently been extended …

Identification Of Human Pgc-1Α-B Isoforms Using A Novel Pgc-1Α-B Specific Antibody, Shannon Hedrick

Theses and Dissertations

Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is known as the master regulator of mitochondrial biogenesis. PGC-1α holds this role by acting as a transcriptional coactivator for an array of transcription factors and nuclear hormone receptors, such as NRF-1/2 and ERRα/γ, whose downstream targets function in mitochondrial biogenesis and oxidative phosphorylation. PGC-1α is regulated both at the transcriptional and post-translational level in several signaling pathways, including p38 MAPK and AMPK. This regulation affects which transcription factor binding events can occur in a given tissue, and thus affects regulation of PGC-1α target genes. PGC-1α is downregulated in many neurodegenerative disorders as …