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Prevalence, Hematological Parameters, And Coagulation Profiles: Cardiovascular Diseases Statistics In The Asir Region, Saudi Arabia, Kholoud N. Almetairi, Sultan Z. Alasmari, Mohammed H. Makkawi, Ahmad A. Shaikh
Prevalence, Hematological Parameters, And Coagulation Profiles: Cardiovascular Diseases Statistics In The Asir Region, Saudi Arabia, Kholoud N. Almetairi, Sultan Z. Alasmari, Mohammed H. Makkawi, Ahmad A. Shaikh
Saudi Medical Journal
Objectives: To determine the prevalence of cardiovascular disease (CVD) types in the Asir region of Saudi Arabia and the importance of hematological testing for CVD patients in the context of disease management. Methods: This retrospective study comprised 416 CVD patients, and samples were divided based the type of CVD. The Mann Whitney U test was used to compare patients’ hematological markers and coagulation profiles to those of healthy controls. Results: The rate of ischemic heart disease (IHD) was 80.7% that of other CVDs, and the rate of ST-elevation myocardial infarction (STEMI) was 37.3% the rate of CVD. Significant differences were …
1 In 6 People Globally Affected By Infertility: Who
1 In 6 People Globally Affected By Infertility: Who
Saudi Medical Journal
No abstract provided.
Systematic Review And Pooled Analysis Of Randomized Controlled Trials In Countries Of The Gulf Cooperation Council (Gcc): Methods And Quality Assessment, Khalid S. Alraddadi, Fayzah H. Al-Adwani, Rajaa M. Al-Raddadi, Sultan H. Alamri, Iman K. Ramadan, Ahmad A. Mirza
Systematic Review And Pooled Analysis Of Randomized Controlled Trials In Countries Of The Gulf Cooperation Council (Gcc): Methods And Quality Assessment, Khalid S. Alraddadi, Fayzah H. Al-Adwani, Rajaa M. Al-Raddadi, Sultan H. Alamri, Iman K. Ramadan, Ahmad A. Mirza
Saudi Medical Journal
Objectives: To describe variations in characteristics of randomized controlled trials conducted in the Gulf Cooperation Council (GCC) countries, and critically appraising the quality of design, conduct and analysis of the trials. Methods: We carried out a systematically comprehensive electronic search of articles published between 1990 and 2018 and indexed in several databases: i) MEDLINE/PubMed, ii) EMBASE, iii) Cochrane Central Register of Controlled Trials (CENTRAL), iv) ClinicalTrials.gov, and v) World Health Organization International Clinical Trials Registry Platform. We summarized the overall risk of bias present in all analyzed studies using the Cochrane Collaboration risk of bias tool (CCRBT). Results: A remarkable …
The Histopathological Effects Of Sleep Disorders On Striated Muscle In Rats, İlkay Çinar, Muhammed Bozoğlan, Kürşad Aytekin, Deniz Esenyel, Cem Zeki Esenyel
The Histopathological Effects Of Sleep Disorders On Striated Muscle In Rats, İlkay Çinar, Muhammed Bozoğlan, Kürşad Aytekin, Deniz Esenyel, Cem Zeki Esenyel
Saudi Medical Journal
Objectives: To histopathologically examine the change in gastrocnemius muscle created by sleep disorder in rats. Methods: This study was carried out at Giresun University, Turkey from December 2018 to January 2021. A total of 30 Wistar rats were separated into 3 groups as the control group (CG), absence of rapid eye movement (REM) sleep (ARS) group, chronic absence of sleep (CAS) group. The lack of sleep was created in all rats. At the end of 21 days, all the rats were euthanized. Degeneration and regeneration findings, and expressions of muscle RING finger 1 (MuRF1), muscle atrophy F-box (MAFbx), tumor necrosis …
Frequency Of The Rs2015 (T>G) And Rs2241703 (G>A) Polymorphisms In The Mirna-Sirt2 Gene In Type 2 Diabetes Mellitus In Saudi Arabia, Nahla A. Alshaikh, Siddig I. Abdelwahab, Mahmoud M. Habibullah, Ahmed A. Jerah, Mohammed A. Bakri, Yahia A. Kaabi
Frequency Of The Rs2015 (T>G) And Rs2241703 (G>A) Polymorphisms In The Mirna-Sirt2 Gene In Type 2 Diabetes Mellitus In Saudi Arabia, Nahla A. Alshaikh, Siddig I. Abdelwahab, Mahmoud M. Habibullah, Ahmed A. Jerah, Mohammed A. Bakri, Yahia A. Kaabi
Saudi Medical Journal
Objectives: To investigate the prevalence of rs2015 (T>G) and rs2241703 (G>A) polymorphisms in the miRNA-SIRT2 gene in Saudi Arabia and their possible associations with type 2 diabetes mellitus (T2DM). Methods: Blood samples were collected from 428 participants from Jazan University Hospital, Jazan, Saudi Arabia between September 2021 and June 2022 and subjected to TaqMan single-nucleotide polymorphisms (SNP) genotyping assay for rs241703 (G>A) and rs2015 (G>T). Genotype frequencies were determined in control (n=217). Results: The A allele of rs2241703 was undetected in our population, and all samples carried the GG genotype. The rs2015 SNP frequency was 29.4% …
Clinicopathologic Characteristics And Outcomes Of Patients With Mycosis Fungoides: A Single Tertiary Center Retrospective Analysis In Saudi Arabia, Faisal A. Alghubaywi, Sawsan A. Alharthi, Sarah S. Aldharman, Raneem H. Najjar, Majed Y. Aleissa, Ohoud Z. Aljarbou, Mohammed I. Aljasser, Mohammad A. Almohideb
Clinicopathologic Characteristics And Outcomes Of Patients With Mycosis Fungoides: A Single Tertiary Center Retrospective Analysis In Saudi Arabia, Faisal A. Alghubaywi, Sawsan A. Alharthi, Sarah S. Aldharman, Raneem H. Najjar, Majed Y. Aleissa, Ohoud Z. Aljarbou, Mohammed I. Aljasser, Mohammad A. Almohideb
Saudi Medical Journal
Objectives: To determine the distinctive clinical and pathological characteristics and outcomes of MF in a Saudi population. Methods: We conducted a retrospective analysis of all MF cases diagnosed clinically with pathological confirmation at King Abdulaziz Medical City in Riyadh from January 2016 to July 2022. Variables include demographical, clinical, and pathological MF traits and disease outcomes. Results: A sum of 73 patients were enrolled. The mean age was 44 years. The female-to-male ratio was 1.3:1. The mean duration between cutaneous manifestations and MF diagnosis was 33 months (2.7 years). Classic MF was the most common variant (60.3%), followed by hypopigmented …
Potential Barriers To The Daily Use Of Hearing Aids In Children, Medhat F. Yousef, Ziyad I. Dhayan, Tahera Islam, Fahad Z. Alotabi, Eman A Hajr
Potential Barriers To The Daily Use Of Hearing Aids In Children, Medhat F. Yousef, Ziyad I. Dhayan, Tahera Islam, Fahad Z. Alotabi, Eman A Hajr
Saudi Medical Journal
Objectives: To identify factors affecting hearing aid usage in children. Methods: This retrospective study examined 59 hearing-impaired children fitted with hearing aids for at least 6 months. Patients with moderate to profound sensorineural hearing loss with complete data-logging information stored in the hearing aid programming file from January 2020 until June 2021 were included. Children with concomitant disabilities were excluded. Data for audiological assessments included hearing assessment, aided hearing thresholds, and aided speech tests. Results: The children’s age ranged from 6 months to 6 years. Average daily hearing aid usage was 5.5 hour (h) after 3 months, 7 h after …
Vitamin D Status Among Residents Of Molidawa Daur Autonomous Banner, Inner Mongolia, North China, Jingwen Hu, Yunmei Liang, Guiping Wen, Dezhong Chen, Yuanjing Liu, Hongmei Zhang, Xiaosong Qin
Vitamin D Status Among Residents Of Molidawa Daur Autonomous Banner, Inner Mongolia, North China, Jingwen Hu, Yunmei Liang, Guiping Wen, Dezhong Chen, Yuanjing Liu, Hongmei Zhang, Xiaosong Qin
Saudi Medical Journal
Objectives: To retrospectively analyze the vitamin D (VD) status of residents in northeastern Inner Mongolia and its relationship with the average monthly sunshine hours. Methods: Serum 25-hydroxyvitamin D[s-25(OH)D] samples from 4982 outpatients (2092 males) in Moli Dawa Daur Autonomous Banner People’s Hospital, Hulunbuir, China from July 2018 to January 2022 were included in this study. Results: The overall median s-25(OH)D was 53.3 nmol/L, VD deficiency (<30 nmol/L), deficiency (30-50 nmol/L), sufficient (>50-250 nmol/L) and excess (>250 nmol/L) were 16% (796/4982), 30% (1495/4982), 53.4% (2658/4982) and 0.7% (33/4982). There were statistically significant differences in median s-25(OH)D by month, age-groups and gender ( p <0.001). Low VD status (LVDS, including VD deficiency and insufficiency) in females was 54.6% and males was 33.9%, and the LVDS composition differed significantly by age-group and month ( p <0.05). The changing trend of the median s-25(OH)D level was similar to the monthly average sunshine hours, with a slight lag. Conclusion: Nearly half of residents live in LVDS. LVDS is affected by month, gender, and age.
Comment On: Prevalence Of Transfusion-Transmitted Infections In Saudi Arabia Blood Donors: A Nationwide, Cross-Sectional Study, Nour Al-Mozain, Maha A. Badawi, Mohammad A. Alfhili
Comment On: Prevalence Of Transfusion-Transmitted Infections In Saudi Arabia Blood Donors: A Nationwide, Cross-Sectional Study, Nour Al-Mozain, Maha A. Badawi, Mohammad A. Alfhili
Saudi Medical Journal
No abstract provided.
Can Moderate Dietary Salt Restriction Help Patients With Hypertension?
Can Moderate Dietary Salt Restriction Help Patients With Hypertension?
Saudi Medical Journal
No abstract provided.
Statement On The Update Of Who’S Working Definitions And Tracking System For Sars-Cov-2 Variants Of Concern And Variants Of Interest
Saudi Medical Journal
No abstract provided.
Who And Gilead Sciences Extend Collaborative Agreement To Enhance Access To Treatment For Visceral Leishmaniasis
Saudi Medical Journal
No abstract provided.
The Role Of Teleradiology During Covid-19 Outbreak: Saudi Radiologists’ Perspectives, Shrooq T. Al-Dahery, Walaa M. Alsharif, Fatima H. Alamri, Shahad A. Nawawi, Wed K. Mofti, Fahad H. Alhazmi, Khalid M. Alshamrani, Awadia G. Suliman, Abdulaziz A. Qurashi
The Role Of Teleradiology During Covid-19 Outbreak: Saudi Radiologists’ Perspectives, Shrooq T. Al-Dahery, Walaa M. Alsharif, Fatima H. Alamri, Shahad A. Nawawi, Wed K. Mofti, Fahad H. Alhazmi, Khalid M. Alshamrani, Awadia G. Suliman, Abdulaziz A. Qurashi
Saudi Medical Journal
Objectives: To evaluate the role of teleradiology during the COVID-19 pandemic from Saudi radiologists’ perspectives to improve the radiology quality service. Methods: A cross-sectional study was carried out in Saudi Arabia among radiologists working at local hospitals from October to November 2021. It contains 21 questions involved demographic information; general information on teleradiology services; and the impact of teleradiology during COVID-19. One-way ANOVA was used to compare demographic groups. Chi-square test was used to compare demographic groups regarding their distribution of responses. All tests were carried out <0.05 level of significance. Results: A total of 102 radiologists participated in this study (56% males, 44% females), 58.8% of them were sub-specialized in chest radiology. Regarding the general status of teleradiology, 69.6% of participants believed that teleradiology is a helpful tool for imaging interpretation. However, 44% of them were uncertain on the impact of teleradiology on patients’ confidentiality. Approximately 87% of participants agreed that there is a positive contribution of teleradiology during COVID-19, which enables decreasing risk of infection and workload. There was a significant difference between professional degrees and overall participant responses ( p <0.05). Academicians agreed that it enhances radiology departments’ work (mean=17.78, SD=1.86). Conclusion: Concerns raised on complicated cases that require physical presence of patients, cannot be performed by teleradiology. Additionally, it might provide insufficient communication with other professionals to discuss images.
The Utilization Of Artificial Intelligence Applications To Improve Breast Cancer Detection And Prognosis, Walaa M. Alsharif
The Utilization Of Artificial Intelligence Applications To Improve Breast Cancer Detection And Prognosis, Walaa M. Alsharif
Saudi Medical Journal
Breast imaging faces challenges with the current increase in medical imaging requests and lesions that breast screening programs can miss. Solutions to improve these challenges are being sought with the recent advancement and adoption of artificial intelligent (AI)-based applications to enhance workflow efficiency as well as patient-healthcare outcomes. rtificial intelligent tools have been proposed and used to analyze different modes of breast imaging, in most of the published studies, mainly for the detection and classification of breast lesions, breast lesion segmentation, breast density evaluation, and breast cancer risk assessment. This article reviews the background of the Conventional Computer-aided Detection system …
Prevalence Of Pelvic Floor Disorders In The Eastern Mediterranean Region: A Meta-Analysis, Hassan M. Elbiss, Wardah Rafaqat, Khalid S. Khan
Prevalence Of Pelvic Floor Disorders In The Eastern Mediterranean Region: A Meta-Analysis, Hassan M. Elbiss, Wardah Rafaqat, Khalid S. Khan
Saudi Medical Journal
Objectives: High prevalence of risk factors for pelvic floor disorders (PFD) in the Eastern Mediterranean may result in higher rates of prevalence of PFD in comparison to other regions. Despite individual studies, there are no clear statistics on the cumulative prevalence of PFDs in the East Mediterranean region. The aim of this study was to investigate the prevalence of PFDs in the Eastern Mediterranean region. Methods: A literature search without language restriction was conducted in PubMed, Cochrane database and Web of Science from 2016 to 01 June 2022. Cross-sectional and cohort studies that reported prevalence of urinary incontinence (UI), constipation, …
The Clinical Results Of Lower Trapezius Tendon Transfer With The Peroneus Longus Allograft Augmentation Combined With Interpositional Repair With Fascia Lata In Massive Irreparable Rotator Cuff Tears, Muhammet Bozoğlan, Murat Danışman, Tuğcan Demir, Halil Karaca, Cem Zeki Esenyel
The Clinical Results Of Lower Trapezius Tendon Transfer With The Peroneus Longus Allograft Augmentation Combined With Interpositional Repair With Fascia Lata In Massive Irreparable Rotator Cuff Tears, Muhammet Bozoğlan, Murat Danışman, Tuğcan Demir, Halil Karaca, Cem Zeki Esenyel
Saudi Medical Journal
Objectives: To investigate the clinical results of lower trapezius (LT) tendon transfer and interpositional repair that were performed simultaneously in patients with massive irreparable rotator cuff tears. Methods: Between 2018 and 2020 years, 16 patients with massive irreparable rotator cuff tears that were treated with LT tendon transfer and interpositional repair at the same time were included in this study. The mean follow-up period was 29±3 months (24-39 months) and the mean age of patients was 62±9 years (42-73 years). The acromio-humeral distance, active range of motions, Visual Analog Scale (VAS) scores, University of California-Los Angeles (UCLA) scores and Constant-Murley …
Does The Preoperative Fasting Period Affect The Liver In A Distant Organ Model Of Renal Ischaemia Reperfusion?, Yasemin Akcaalan, Ersin Gurkan Dumlu, Ebru Menekse, Mustafa Cem Yilmaz, Ezgi Erkilic, Betul Ogut, Aylin Sepıcı Dıncel
Does The Preoperative Fasting Period Affect The Liver In A Distant Organ Model Of Renal Ischaemia Reperfusion?, Yasemin Akcaalan, Ersin Gurkan Dumlu, Ebru Menekse, Mustafa Cem Yilmaz, Ezgi Erkilic, Betul Ogut, Aylin Sepıcı Dıncel
Saudi Medical Journal
Objectives: To experimentally evaluate the effects of preoperative fasting duration on distant organ liver in renal ischaemia-reperfusion (IR) injury. Methods: This is an experimental study. In the study, 3 groups were formed. In Group A, abdominal laparotomy was carried out after 12 hours of preoperative fasting without any IR damage. In Group B, IR injury was carried out after 12 hours of preoperative fasting, and abdominal laparotomy was carried out, in Group C after 2 hours of fasting after IR injury. Apoptosis, congestion, balloon degeneration, nuclear pleomorphism, and leukocyte infiltration were examined histopathologically and tumor necrosis factor-alpha (TNF-α), interleukin (IL) …
Real Time Endobronchial Ultrasound Transbronchial Needle Aspiration For The Diagnosis Of Tuberculous Intrathoracic Lymphadenopathy: Saudi Arabian Western Region Experience, Ahmed A. Aljohaney
Real Time Endobronchial Ultrasound Transbronchial Needle Aspiration For The Diagnosis Of Tuberculous Intrathoracic Lymphadenopathy: Saudi Arabian Western Region Experience, Ahmed A. Aljohaney
Saudi Medical Journal
Objectives: To assess the utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for presumptive tuberculosis (TB) patients with intrathoracic enlarged lymph nodes in a country with low to moderate TB incidence. Methods: Thirty-one patients with clinical features of TB and intrathoracic lymphadenopathy, who had EBUS-TBNA sampling and final confirmation of intrathoracic TB lymphadenopathy, were retrospectively reviewed over an 8-year period. Routine clinical and laboratory evaluations including computerized tomography scans were performed before the EBUS-TBNA. Sociodemographic characteristics, clinical profile, pathological, and microbiological findings were collected. Results: The EBUS-TBNA confirmed TB diagnosis in 26 (83.9%) subjects with a consistent pathological finding or …
Presentations Of Active Substance Use In The Emergency Department: A Single Center’S Perspective Study In Riyadh, Saudi Arabia, Mohammed K. Alageel, Alshamoos A. Alwassel, Hamad A. Almohsen
Presentations Of Active Substance Use In The Emergency Department: A Single Center’S Perspective Study In Riyadh, Saudi Arabia, Mohammed K. Alageel, Alshamoos A. Alwassel, Hamad A. Almohsen
Saudi Medical Journal
Objectives: To explore the most common clinical presentations of active substance users in our institution’s Emergency Department (ED). Methods: This was a retrospective chart review of all patients that were brought to the ED of King Saud University Medical City in Riyadh, Saudi Arabia thought to be actively using illicit substances, between January 2019 and December 2021. Those with incomplete data were excluded. Results: A total of 582 patients were included in the study, 532 (91.4%) males, the majority were in the age group 21-30 years old (53.1%). Most patients were fully alert (n=405, 69.6%). Overall, cannabis was used by …
Assessing The Adverse Effects Of Covid-19 Vaccine In Different Scenarios In Saudi Arabia: A Cross-Sectional Study, Ahad Amer Alsaiari, Mamdouh Allahyani, Abdulelah Aljuaid, Alaa Shafie, Ayman Al-Hazmi, Haytham A. Dahlawi, Osama Abdulaziz, Ebtisam Alosimi, Albatool Alzaidi, Mazen Almehmadi
Assessing The Adverse Effects Of Covid-19 Vaccine In Different Scenarios In Saudi Arabia: A Cross-Sectional Study, Ahad Amer Alsaiari, Mamdouh Allahyani, Abdulelah Aljuaid, Alaa Shafie, Ayman Al-Hazmi, Haytham A. Dahlawi, Osama Abdulaziz, Ebtisam Alosimi, Albatool Alzaidi, Mazen Almehmadi
Saudi Medical Journal
Objectives: To assess the different side effects of COVID-19 vaccines at different scenarios in Saudi Arabia. Methods: This cross-sectional study sought to investigate the side effects of COVID-19 vaccines through an online survey of 2,718 participants in Saudi Arabia. Results: People can manage their expectations about vaccine side effects and deal with symptoms better by knowing beforehand that they are likely to experience mild side effects for a short period, symptoms that are manifested regardless of age, and infection before or after vaccination. There are certain uncommon side effects that affect more people who got infected, and not before vaccination; …
Prevalence Of Microvascular Complications Among Patients With Type 2 Diabetes Mellitus Who Visited Diabetes Clinics In Saudi Arabia, Mounther M. Alnaim, Abdullah Alrasheed, Abdullah A. Alkhateeb, Mohammed M. Aljaafari, Abdulrahman Alismail
Prevalence Of Microvascular Complications Among Patients With Type 2 Diabetes Mellitus Who Visited Diabetes Clinics In Saudi Arabia, Mounther M. Alnaim, Abdullah Alrasheed, Abdullah A. Alkhateeb, Mohammed M. Aljaafari, Abdulrahman Alismail
Saudi Medical Journal
Objectives: To determine the microvascular complications prevalence in patients with type 2 diabetes mellitus (DM) in the eastern province of the Kingdom of Saudi Arabia. Methods: The participants in this retrospective, cross-sectional study included patients with type 2 DM who visited the diabetes clinics of primary health care centers of 2 National Guard Hospitals, Eastern Province, Saudi Arabia. Results: This study included 935 patients with type 2 diabetes (54.1% women versus 45.9% men). Oral hypoglycemic medication was the most common treatment (90.3%). Overall, 55.1% of patients visited the ophthalmology clinic for retinopathy screening. The last glycated hemoglobin A1c result (mean: …
Do Certain Jobs Increase A Woman’S Risk Of Pregnancy Loss?
Do Certain Jobs Increase A Woman’S Risk Of Pregnancy Loss?
Saudi Medical Journal
No abstract provided.
Five Billion People Unprotected From Trans Fat Leading To Heart Disease
Five Billion People Unprotected From Trans Fat Leading To Heart Disease
Saudi Medical Journal
No abstract provided.
Saudi Medical Journal 2022, Fahdah Alokaily
Saudi Medical Journal 2022, Fahdah Alokaily
Saudi Medical Journal
No abstract provided.
Why Do Many Young Cancer Survivors Forgo Human Papillomavirus Vaccination?
Why Do Many Young Cancer Survivors Forgo Human Papillomavirus Vaccination?
Saudi Medical Journal
No abstract provided.
Impact Of Diabetes Mellitus And Co-Morbidities On Mortality In Patients With Covid-19: A Single-Center Retrospective Study, Anees A. Sindi, Wail A. Tashkandi, Mohammed W. Jastaniah, Mohammed A. Bashanfar, Ahmed F. Fakhri, Fahad S. Alsallum, Hamdan B. Alguydi, Alyaa Elhazmi, Talal A. Al-Khatib, Maha M. Alawi, Ibrahim Abushoshah
Impact Of Diabetes Mellitus And Co-Morbidities On Mortality In Patients With Covid-19: A Single-Center Retrospective Study, Anees A. Sindi, Wail A. Tashkandi, Mohammed W. Jastaniah, Mohammed A. Bashanfar, Ahmed F. Fakhri, Fahad S. Alsallum, Hamdan B. Alguydi, Alyaa Elhazmi, Talal A. Al-Khatib, Maha M. Alawi, Ibrahim Abushoshah
Saudi Medical Journal
Objectives: To describe the effect of diabetes mellitus (DM) on clinical outcomes of patients admitted with COVID-19 infection. Methods: We carried out a single center, observational, retrospective study. We included adult patients with laboratory-confirmed diagnosis of COVID-19 admitted to a tertiary hospital in Jeddah, Saudi Arabia, from April 2020 to December 2020. Electronic medical records were reviewed for demographics, clinical status, hospital course, and outcome; and they were compared between the patients with or without DM. Results: Out of 198 patients included in the study, 86 (43.4%) were diabetic and 112 (56.5%) were non-diabetic. Majority of the patients were males …
Early Recognition Of Pulmonary Complications Of Sickle Cell Disease, Rayyan M. Almusally
Early Recognition Of Pulmonary Complications Of Sickle Cell Disease, Rayyan M. Almusally
Saudi Medical Journal
Sickle cell disease (SCD) is an inherited hematological disorder with multiple-organ involvement. The pulmonary complications of SCD are associated with significant morbidity and mortality. This article presents an important review of acute and chronic pulmonary complications, including acute chest syndrome, pneumonia, pulmonary thromboembolism, pulmonary fat embolism, chronic sickle cell lung disease, and pulmonary hypertension, in patients with SCD. Bronchial asthma and obstructive sleep apnea in relation to SCD are discussed in this article. Early recognition of pulmonary complications leads to early therapeutic interventions and improvement of the overall treatment outcome.
In This Issuereview Articleoriginal Articles
In This Issuereview Articleoriginal Articles
Saudi Medical Journal
No abstract provided.
The Expression And Significance Of Long Non-Coding Rna Itgb2-As1 In Renal Clear Cell Carcinoma, Wei Zhou, Zhi-Gang Liu, Lian-Qu Wang
The Expression And Significance Of Long Non-Coding Rna Itgb2-As1 In Renal Clear Cell Carcinoma, Wei Zhou, Zhi-Gang Liu, Lian-Qu Wang
Saudi Medical Journal
Objectives: To explore the expression and significance of long non-coding RNA ITGB2-AS1 in kidney renal clear cell carcinoma (KIRC). Methods: The expression of ITGB2-AS1 in KIRC tissues of 45 KIRC patients in the first affiliated hospital of Henan University, Henan, China, from September 2018 to December 2020, KIRC cells were detected and the relationship of ITGB2-AS1 and overall survival of KIRC patients were analyzed. The expression of ITGB2-AS1 in KIRC cells Caki-1 and ACHN was interfered, and the changes of cell proliferation, invasion, migration, and apoptosis were detected. Dual luciferase reporter gene assay and RNA pull-down assay were carried out …
Primary Lymphoma Of The Kidney: Pathology Experience From 2 Tertiary Hospitals In Western Saudi Arabia, Jaudah A. Al-Maghrabi
Primary Lymphoma Of The Kidney: Pathology Experience From 2 Tertiary Hospitals In Western Saudi Arabia, Jaudah A. Al-Maghrabi
Saudi Medical Journal
Objectives: To document the clinicopathological features of primary renal lymphoma (PRL) at 2 tertiary hospitals in the western region of the Kingdom of Saudi Arabia. Methods: Data were retrieved from all PRLs that were diagnosed at King Abdulaziz University Hospital and King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia, between January 2002 and April 2022. Histopathological and immunohistochemical slides were reviewed, and additional immunohistochemistry stains were carried out in selected cases. Follow-up data were also collected. Results: There were 17 identified cases of PRL. The age of the patients ranged from 4-76 years (median: 50.5 years and mean: …