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Risk Of Malignancy In Thyroid Nodules Bethesda Iii Sub Classification Into Nuclear Atypia And Architectural Atypia. A Retrospective Study Apr 2025

Risk Of Malignancy In Thyroid Nodules Bethesda Iii Sub Classification Into Nuclear Atypia And Architectural Atypia. A Retrospective Study

Saudi Medical Journal

ABSTRACT Objectives: To identify the risk of malignancy in the Bethesda III category based on histopathological subclassification. Methods: We retrospectively analyzed 193 patients with Bethesda III thyroid nodules who underwent surgical resection. The primary outcome was the malignancy risk associated with each histopathological sub-classification. Results: Of 193 patients, final histopathology revealed malignant nodules in 96 (49.7%). The malignancy rates varied among the Bethesda III subcategories, with Hürthle cell atypia of undetermined significance demonstrating the highest rate (55.6%), followed by cytological atypia (55.4%), architectural atypia (50.6%), and combined cytological and architectural atypia (33.3%). However, no significant difference in malignancy rates was …


Many Pregnancy-Related Complications Going Undetected And Untreated – Who Apr 2025

Many Pregnancy-Related Complications Going Undetected And Untreated – Who

Saudi Medical Journal

No abstract provided.


Who Brings Countries Together To Test Collective Pandemic Response Apr 2025

Who Brings Countries Together To Test Collective Pandemic Response

Saudi Medical Journal

No abstract provided.


Impact Of Dietary Intake On Brain Choline Levels: A 3 Tesla Magnetic Resonance Spectroscopy Study, Halima Hawesa, Mayar Alghumaiz, Renad Alghamdi, Nourah Alrabiah, Bayader Alfaifi, Hind Allam, Mahasin Gamalalddin, Haya Alshegri, Mansour Shanawani Mar 2025

Impact Of Dietary Intake On Brain Choline Levels: A 3 Tesla Magnetic Resonance Spectroscopy Study, Halima Hawesa, Mayar Alghumaiz, Renad Alghamdi, Nourah Alrabiah, Bayader Alfaifi, Hind Allam, Mahasin Gamalalddin, Haya Alshegri, Mansour Shanawani

Saudi Medical Journal

Objectives: To investigate the relationship between dietary choices and brain choline (Cho) levels using magnetic resonance spectroscopy (MRS). Methods: A total of 88 female students from the radiology department at King Abdullah bin Abdulaziz University Hospital, Riyadh, Saudi Arabia, participated in this study. Brain total choline (tCho) levels were estimated using MRS single volume sequence at a 3 Tesla field, with an echo time of 30 ms, repetition time of 2000 ms, voxel size of 15x15x15 mm, and water suppression bandwidth of 50 Hz. Participants’ food consumption habits were assessed using a dietary questionnaire to quantify the amount of protein …


Prevalence Of Immunoglobulin E Sensitization To Various Inhaled Allergens Among The Residents Of The Northern United Arab Emirates: Automated Evaluation Of A Membrane-Based Test System, Israa O. Yousif, Nazeerullah Rahamathullah, Nelofar S. Khan, Mohammad Mesbahuzzaman, Mohammed Abdulrazzaq, Fawzia A. Alobeidli, Praveen K. Kandakurti Mar 2025

Prevalence Of Immunoglobulin E Sensitization To Various Inhaled Allergens Among The Residents Of The Northern United Arab Emirates: Automated Evaluation Of A Membrane-Based Test System, Israa O. Yousif, Nazeerullah Rahamathullah, Nelofar S. Khan, Mohammad Mesbahuzzaman, Mohammed Abdulrazzaq, Fawzia A. Alobeidli, Praveen K. Kandakurti

Saudi Medical Journal

Objectives: To determine specific positive immunoglobulin E (IgE) antibodies to various inhaled allergens in residents of Ajman and the northern region of the United Arab Emirates (UAE) using an automated evaluation of a membrane-based test. Methods: A total of 104 patients’ blood samples were received from various hospitals and clinics in Ajman and other northern Emirates regions at Thumbay Laboratory, Thumbay University Hospital, Ajman, UAE, to carry out inhalation allergy tests during the study period of 12 months (February 2023 until January 2024). Using the EUROLINE immunoblotting method, 20 different inhalation allergens-impregnated latex strips were used to carry out the …


Understanding Artificial Intelligence Through The Eyes Of Future Nurses: Insights From Nursing Students, Latifah Alenazi, Saad H. Al-Anazi Mar 2025

Understanding Artificial Intelligence Through The Eyes Of Future Nurses: Insights From Nursing Students, Latifah Alenazi, Saad H. Al-Anazi

Saudi Medical Journal

Objectives: To explore nursing students’ perceptions and understanding of artificial intelligence (AI), aiming to identify and address critical knowledge gaps to support effective integration into educational practices. Methods: An exploratory qualitative study was carried out using semi-structured interviews with 20 nursing students from King Saud University, Riyadh, Saudi Arabia, in October 2023. Data collection focused on their definitions, conceptualizations, and perspectives regarding AI in healthcare. Results: A total of 3 key themes emerged: I)transformation, where AI represents a shift in nursing education from traditional methods to technological integration; II) power, viewing AI as a driver of knowledge creation and scientific …


Mass Polio Vaccination Campaign To Continue In The Gaza Strip Mar 2025

Mass Polio Vaccination Campaign To Continue In The Gaza Strip

Saudi Medical Journal

No abstract provided.


Effects Of Antidiabetic Drugs On The Level Of Serum Uric Acid In Patients Who Have Type 2 Diabetes, Gang Wang, Guixia Wang Mar 2025

Effects Of Antidiabetic Drugs On The Level Of Serum Uric Acid In Patients Who Have Type 2 Diabetes, Gang Wang, Guixia Wang

Saudi Medical Journal

ABSTRACT Hyperuricemia and type 2 diabetes mellitus (T2DM) are interconnected, in that each disorder increases risk for the other. Some antidiabetic drugs may decrease the level of serum uric acid (SUA). This narrative review describes the effects of multiple antidiabetic drugs on the SUA level and their possible mechanisms of action in patients with T2DM. The results showed that sodium glucose contransporter-2 inhibitors (SGLT2is), thiazolidinediones, metformin, and linagliptin decreased the SUA; insulin, sitagliptin, and alogliptin increased the SUA; and glucagon-like peptide-1 receptor agonists (GLP-1 RAs), sulfonylureas, and alpha-glucosidase inhibitors had little effect on the SUA. Sodium glucose contransporter-2 inhibitors appeared …


Effectiveness Of Social Skills Training Interventions For Children With Autism Spectrum Disorder: A Systematic Review And Meta-Analysis, Fatimah S. Alahmari, Abdulhadi A. Alhabbad, Hussain A. Alshamrani, Mohammed A. Almuqbil Mar 2025

Effectiveness Of Social Skills Training Interventions For Children With Autism Spectrum Disorder: A Systematic Review And Meta-Analysis, Fatimah S. Alahmari, Abdulhadi A. Alhabbad, Hussain A. Alshamrani, Mohammed A. Almuqbil

Saudi Medical Journal

Objectives: To evaluatethe effectiveness of social skills training (SST) interventions for children with autism spectrum disorder (ASD). Methods: A systematic review and meta-analysis were carried out to identify relevant studies published between 2000-2023. The study was conductedin accordance with the PRISMA guidelines. Studies were included if they met the following criteria: randomized controlled trials (RCTs) or quasi-RCTs, participants were children with ASD aged 3-18 years, SST interventions were delivered individually or in groups, and social skills were assessed using standardized measures. Effect sizes were calculated using Cohen’s d, and meta-analyses were carried out using a random-effects model. Results: A total …


The Prevalence Of Alzheimer’S Disease Among Diabetic Patients In Saudi Arabia, Alhanouf S. Alqudah, Nahed S. Abaalkhail, Alanoud S. Alturki, Yasmen S. Naseer, Sara K. Almansour Mar 2025

The Prevalence Of Alzheimer’S Disease Among Diabetic Patients In Saudi Arabia, Alhanouf S. Alqudah, Nahed S. Abaalkhail, Alanoud S. Alturki, Yasmen S. Naseer, Sara K. Almansour

Saudi Medical Journal

Objectives: To investigate the knowledge of Alzheimer’s disease (AD) among 228 Saudi adults with diabetes, aiming to assess cognitive awareness through a questionnaire. It explores risk factors, symptoms, prevention strategies, and attitudes towards dementia, while integrating demographic data to illuminate cognitive landscapes and correlations between diabetes and cognitive health. Methods: Trained dietitians administered questionnaires to 228 adult Saudi diabetic participants, focusing on their understanding of AD across various domains. The study employed validated tools for data collection and amalgamated responses with demographic and medical details. Results: Of the 228 participants, 56.6% were female. Findings revealed a high acknowledgment of 3 …


Hospital Readmission After An Acute Admission To Internal Medicine: Causes And Risk Factors In A Tertiary Care Center In Saudi Arabia, Mutaz H. Althobaiti, Khaled A. Alkhowaiter, Duha K. Alahmadi, Omar S. Baharoon, Al-Zahraa S. Almahlawi, Mohammed Alqahtani, Hamdan H. Al-Jahdali, Jinan Z. Shamou, Laila A. Layqah, Salim A. Baharoon Mar 2025

Hospital Readmission After An Acute Admission To Internal Medicine: Causes And Risk Factors In A Tertiary Care Center In Saudi Arabia, Mutaz H. Althobaiti, Khaled A. Alkhowaiter, Duha K. Alahmadi, Omar S. Baharoon, Al-Zahraa S. Almahlawi, Mohammed Alqahtani, Hamdan H. Al-Jahdali, Jinan Z. Shamou, Laila A. Layqah, Salim A. Baharoon

Saudi Medical Journal

Objectives: To investigate the risk factors associated with single and multiple hospital readmissions within 30 days of discharge. Methods: A retrospective study carried out during 2019 at King Abdulaziz Medical City in Riyadh, Saudi Arabia. Using simple random sampling with an estimated prevalence of readmission rates between 10-20%, the calculated sample size was 200 patients. Patients were classified into 2 categories: patients with single or multiple readmissions. For comparison of categorical variables, the Chi-square test and Fisher’s exact test were employed as relevant. Means comparisons were carried out using independent samples t-test. Multivariate logistic regression analysis was implemented to identify …


Safety And Efficacy Of Weekly Somapacitan For Growth Hormone Deficiency In Children: A 72-Week Observational Study, Abdulmoein E. Al-Agha, Hasan M. Aljefri, Shahd E. Kafi, Aliaa S. Alamri, Abdullah A. Alghamdi Mar 2025

Safety And Efficacy Of Weekly Somapacitan For Growth Hormone Deficiency In Children: A 72-Week Observational Study, Abdulmoein E. Al-Agha, Hasan M. Aljefri, Shahd E. Kafi, Aliaa S. Alamri, Abdullah A. Alghamdi

Saudi Medical Journal

Objectives: To assess the effectiveness and safety of somapacitan, a long-acting growth hormone analog, as a promising treatment to improve adherence in pediatric growth hormone deficiency (GHD) management. Methods: The observational study included 184 children diagnosed with GHD. Carried out over 72 weeks at the Pediatric Endocrinology Outpatient Clinic in collaboration with King Abdulaziz University Hospital in Jeddah, Saudi Arabia. Patients received weekly somapacitan doses, starting at 0.16 mg/kg and adjusted according to insulin-like growth factor 1 (IGF-1) levels. Key outcomes included changes in height velocity and IGF-1 levels, with statistical significance set at a p -value of <0.05. Results: The cohort, with an average age of 10.1 years and 67.4% male, showed substantial improvements by week 72: IGF-1 levels increased from 166.97 to 363.74, and height velocity gains were most pronounced in children at Tanner Stage 1. Treatment-naive children exhibited greater initial height velocity improvements compared to those switching from daily GH therapy, although these differences leveled over time. Somapacitan was well-tolerated, with minimal side effects, supporting its long-term safety. Conclusion: Weekly somapacitan offers an effective, safe pediatric GHD treatment, with individualized dosing based on IGF-1 levels. Routine IGF-1 monitoring is advised to maximize benefits and minimize risks. Further studies on diverse populations are recommended to validate these findings in pediatric endocrinology.


The Prevalence And Predictors Of Obstructive Sleep Apnea In Patients Undergoing Bariatric Surgery In Saudi Arabia, Alaa M. Alaqeel, Mohammed A. Aldammas, Enas F. Alaraik, Faisal M. Abanumay, Salih A. Aleissi, Samar Z. Nashwan, Awad H. Olaish, Hamza O. Dhafar, Ahmed S. Bahammam Mar 2025

The Prevalence And Predictors Of Obstructive Sleep Apnea In Patients Undergoing Bariatric Surgery In Saudi Arabia, Alaa M. Alaqeel, Mohammed A. Aldammas, Enas F. Alaraik, Faisal M. Abanumay, Salih A. Aleissi, Samar Z. Nashwan, Awad H. Olaish, Hamza O. Dhafar, Ahmed S. Bahammam

Saudi Medical Journal

Objectives: To address a gap in the literature on the prevalence and predictors of obstructive sleep apnea (OSA) among patients undergoing bariatric surgery in Saudi Arabia, considering the region’s unique cultural and dietary practices. Methods: This retrospective study at King Saud University Medical City, Riyadh, analyzed data from morbidly obese patients referred from the bariatric surgery unit to the sleep disorders clinic. Using the Sleep Disorders Center database (September 2015 to March 2019), it examined demographic and clinical variables, with in-laboratory polysomnography (PSG) employed to diagnose and assess OSA severity. Results: The study assessed 265 morbidly obese patients for OSA …


Healthcare Professionals’ Perceptions Of Electronic Medical Record Privacy And Its Impact On Work Quality In Riyadh Hospitals, Alaa A. Qashqari, Dunya S. Almutairi, Soukaina A. Ennaceur, Nesren S. Farhah, Mohammed A. Almohaithef Mar 2025

Healthcare Professionals’ Perceptions Of Electronic Medical Record Privacy And Its Impact On Work Quality In Riyadh Hospitals, Alaa A. Qashqari, Dunya S. Almutairi, Soukaina A. Ennaceur, Nesren S. Farhah, Mohammed A. Almohaithef

Saudi Medical Journal

Objectives: To investigate healthcare professionals’ perceptions of electronic medical records (EMRs) privacy and its impact on work quality in Riyadh, Saudi Arabia, hospitals. Methods: A total of 381 healthcare professionals were surveyed using a self-administered online questionnaire, which collected data on their familiarity with EMRs, perceptions of data protection, and experiences with privacy breaches. Results: The findings revealed that 79.3% of the respondents were familiar with EMRs. However, only 69.6% expressed confidence in safeguarding patient data from unauthorized access. Alarmingly, 25.5% admitted to accessing colleagues’ EMRs without permission, raising significant privacy concerns. Despite the presence of organizational privacy policies, 24.6% …


Validity And Reliability Of The Arabic Version Of Topical Corticosteroid Phobia (Topicop©) Questionnaire, Hashem M. Al-Dujaily, Huda A. Hussein, Bahaa Abdelrahim, Mohammad Shawer, Ahmad Mehyar, Baha’ Aljeradat, Dima Batarseh, Sarah Khraim, Amjad Abdeen, Noor Almaani Mar 2025

Validity And Reliability Of The Arabic Version Of Topical Corticosteroid Phobia (Topicop©) Questionnaire, Hashem M. Al-Dujaily, Huda A. Hussein, Bahaa Abdelrahim, Mohammad Shawer, Ahmad Mehyar, Baha’ Aljeradat, Dima Batarseh, Sarah Khraim, Amjad Abdeen, Noor Almaani

Saudi Medical Journal

Objectives: To translate the topical corticosteroid phobia (TOPICOP) scale into Arabic and assess its validity, reliability, and feasibility. Methods: A cross-sectional study was carried out at Jordan University Hospital, Amman, Jordan, in 2 phases. Phase one involved translation of the TOPICOP scale into Arabic using a 2-step process, followed by pilot testing and content validation by 6 bilingual dermatologists. Phase 2 involved subsequent validation and feasibility testing on a larger sample of 145 participants. To assess reliability, the scale was administered twice for test-retest analysis. Results: Calculated content validity indices revealed satisfactory values, establishing content validation of the Arabic version. …


Does Pain Affect Cancer Survivors’ Use Of Non-Opioid Substances? Mar 2025

Does Pain Affect Cancer Survivors’ Use Of Non-Opioid Substances?

Saudi Medical Journal

No abstract provided.


Groundbreaking Ebola Vaccination Trial Launches Today In Uganda Mar 2025

Groundbreaking Ebola Vaccination Trial Launches Today In Uganda

Saudi Medical Journal

No abstract provided.


Spectrum And Classification Of Atp7b Variants With Clinical Correlation In Children With Wilson Disease, Ruqayah Gy. Al-Obaidi, Bassam Ms. Al-Musawi Feb 2025

Spectrum And Classification Of Atp7b Variants With Clinical Correlation In Children With Wilson Disease, Ruqayah Gy. Al-Obaidi, Bassam Ms. Al-Musawi

Saudi Medical Journal

Objectives: To study the spectrum and classification of ATP7B variants in Iraqi children with Wilson disease by direct gene sequencing with clinical correlation. Methods: Fifty-five unrelated children with a clinical diagnosis of Wilson disease (WD) were recruited. Deoxyribonucleic acid was extracted from peripheral blood samples, and variants in the ATP7B gene were identified using next-generation sequencing. Results: Seventy-six deleterious variants were detected in 97 out of 110 alleles of the ATP7B gene. Thirty (54.5%) patients had 2 disease-causing variants (15 homozygous and 15 compound heterozygous). Twelve (21.8%) patients had one disease-causing variant and one variant of uncertain significance (VUS) with …


Neutrophil-To-Lymphocyte Ratio, Platelets-To-Lymphocyte Ratio, And Red Cell Distribution Width As Prognostic Indicators For Length Of Hospital Stay In Pediatric Asthma, Ebtihal E. Eltyeb, Gassem A. Gohal, Sami A. Alhazmi, Mohammed A. Alqassim, Ehab F. Hakami, Mnar H. Moafa, Najla H. Mutahar, Maisaa M. Shanaq, Sara M. Shanaq, Abdullah J. Almalki, Asmaa A. Jabrah, Shorouq A. Mashhour, Ali A. Dagreri, Rahaf S. Othathi, Siddig Ibrahim Abdelwahab Feb 2025

Neutrophil-To-Lymphocyte Ratio, Platelets-To-Lymphocyte Ratio, And Red Cell Distribution Width As Prognostic Indicators For Length Of Hospital Stay In Pediatric Asthma, Ebtihal E. Eltyeb, Gassem A. Gohal, Sami A. Alhazmi, Mohammed A. Alqassim, Ehab F. Hakami, Mnar H. Moafa, Najla H. Mutahar, Maisaa M. Shanaq, Sara M. Shanaq, Abdullah J. Almalki, Asmaa A. Jabrah, Shorouq A. Mashhour, Ali A. Dagreri, Rahaf S. Othathi, Siddig Ibrahim Abdelwahab

Saudi Medical Journal

Objectives: To examine the relationship between neutrophil-to-lymphocyte ratio (NLR), platelets-to-lymphocyte ratio (PLR), and red cell distribution width (RDW) and the length of hospital stay (LOS) in children with bronchial asthma Methods: This hospital-based study examined the records of children with asthma admitted to Jazan Hospitals, Jazan, Kingdom of Saudi Arabia. Data were extracted at the time of admission. Length of hospital stay and laboratory parameters were acquired from blood. Results: This study involved 489 children, with a mean age of 5.8±3.5 years, of which 59.7% were male. Notably, 77.7% of the patients resided in rural areas of Jazan. The mean …


Concordance Between Homeostatic Model Assessment And Triglyceride Glucose Index In Assessing Insulin Resistance Among Hiv-Infected Patients, Gokcen Gurkok Budak, Aslı Vatan, Ertuğrul Güçlü, Oğuz Karabay Feb 2025

Concordance Between Homeostatic Model Assessment And Triglyceride Glucose Index In Assessing Insulin Resistance Among Hiv-Infected Patients, Gokcen Gurkok Budak, Aslı Vatan, Ertuğrul Güçlü, Oğuz Karabay

Saudi Medical Journal

Objectives: To evaluate the concordance between the triglyceride glucose (TyG) index and the homeostatic model assessment of insulin resistance (HOMA-IR) in assessing insulin resistance (IR) in people living with HIV (PLWH). Additionally, we aimed to estimate a cut-off value for the TyG index in PLWH. Methods: This retrospective, observational study included medical records of patients diagnosed with HIV at Sakarya Training and Research Hospital from January 2019 to January 2024. Based on their HOMA-IR levels, PLWH patients were divided into 2 groups: Group A (patients without IR) and Group B (patients with IR). Results: In this study, insulin resistance was …


Prevalence And Clinical Considerations Of Y Chromosome Microdeletions In Azoospermic And Oligozoopsermic Infertile Men From Al Madinah Al Munawarah, Saudi Arabia, Monis B. Shamsi, Rima Dada, Reham M. Balahmar, Dimah Zaytuni, Ghadeer Alharbi, Syed N. Imam, Emad Rajih, Muhammad Latif, Saif Ahmad Feb 2025

Prevalence And Clinical Considerations Of Y Chromosome Microdeletions In Azoospermic And Oligozoopsermic Infertile Men From Al Madinah Al Munawarah, Saudi Arabia, Monis B. Shamsi, Rima Dada, Reham M. Balahmar, Dimah Zaytuni, Ghadeer Alharbi, Syed N. Imam, Emad Rajih, Muhammad Latif, Saif Ahmad

Saudi Medical Journal

Objectives: To characterize the potential role of Y-chromosome microdeletion (YCM) as a genetic cause for infertility in the Arab population from the Al Madinah Al Munawarah. Methods: We screened 97 infertile men from Al Madinah Al Munawarah, from February 2022 to March 2024. Genomic blood DNA was analyzed for 8 sequence tagged site (STS) markers of Y chromosome by multiplex polymerase chain reaction. Results: We found microdeletions in 3 infertile men, indicating a prevalence of 3.1%. The STS markers sY254 and sY255 corresponding to AZFc regions were deleted in these men. No deletion was observed in any other STS markers …


Association Between Factor I Fibrinogen (Rs6050) And Factor Xi Plasma Thromboplastin (Rs4253417) Genetic Polymorphisms And Recurrent Spontaneous Miscarriage In Saudi Women, Aaishah M. Kaabi, Afrah F. Alkhuriji, Zeneb A. Babay, Ibrahim A. Barakat, Abdullah M. Kaabi, Reem M. Kaabi Feb 2025

Association Between Factor I Fibrinogen (Rs6050) And Factor Xi Plasma Thromboplastin (Rs4253417) Genetic Polymorphisms And Recurrent Spontaneous Miscarriage In Saudi Women, Aaishah M. Kaabi, Afrah F. Alkhuriji, Zeneb A. Babay, Ibrahim A. Barakat, Abdullah M. Kaabi, Reem M. Kaabi

Saudi Medical Journal

Objectives: To identify genetic polymorphisms in factor I fibrinogen (rs6050) and factor XI plasma thromboplastin (rs4253417) in Saudi women with recurrent spontaneous miscarriage (RSM). Furthermore, to compare the levels of clotting factors in the blood of patients and healthy controls. Methods: The current study was conducted at the King Khalid University Hospital in Riyadh, Saudi Arabia, from September 2022 to June 2023. The study involved 100 Saudi women, 50 pregnant and 50 non-pregnant individuals, who experienced RSM. Furthermore, 100 healthy Saudi women, including 50 pregnant and 50 non-pregnant individuals, were also included as controls. TaqMan genotyping assays were used to …


Glp-1ra And Sglt2i Utilization In People With Type 2 Diabetes With Atherosclerotic Cardiovascular Disease (Ascvd) Or At High Risk Of Ascvd In The Gulf Region: Results From The Pact-Mea Studys, Waleed A. Al-Dahi, Saeed H. Khalaf, Dalal A. Alromaihi, Naji M. Alamuddin, Doaa K. Abdalla, Hanan Y. Alfadehla, Amin A. Jayyousi, Mashhood A. Siddique, Usama A. Alalami, Guruprasad C. Subbarao, Shashikanth J. Chetty, Jehan A. Abdulla Feb 2025

Glp-1ra And Sglt2i Utilization In People With Type 2 Diabetes With Atherosclerotic Cardiovascular Disease (Ascvd) Or At High Risk Of Ascvd In The Gulf Region: Results From The Pact-Mea Studys, Waleed A. Al-Dahi, Saeed H. Khalaf, Dalal A. Alromaihi, Naji M. Alamuddin, Doaa K. Abdalla, Hanan Y. Alfadehla, Amin A. Jayyousi, Mashhood A. Siddique, Usama A. Alalami, Guruprasad C. Subbarao, Shashikanth J. Chetty, Jehan A. Abdulla

Saudi Medical Journal

Objectives: To provide insights into the real-world usage of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2i) among individuals with type 2 diabetes (T2D) from Bahrain, Kuwait, and Qatar who either had established atherosclerotic cardiovascular disease (eASCVD) or were at high risk of developing ASCVD. Methods: This study of 1062 adults diagnosed with T2D from Bahrain, Kuwait, and Qatar is a sub-analysis within the Prevalence and Clinical Management of Atherosclerotic Cardiovascular Diseases in Patients with Type 2 Diabetes across Countries in the Middle East and Africa (PACT-MEA) study, a noninterventional, cross-sectional study. Participants were recruited from 13 …


Quality Of Life Improvement In Children With Otitis Media With Effusion Post Ventilation Tube Insertion: A Prospective Cohort Study, Abdullah S. Alkhaldi, Lama M. Alsahli, Sultan A. Al-Ibraheem, Muataz H. Alhashem, Fahad A. Al-Saab Feb 2025

Quality Of Life Improvement In Children With Otitis Media With Effusion Post Ventilation Tube Insertion: A Prospective Cohort Study, Abdullah S. Alkhaldi, Lama M. Alsahli, Sultan A. Al-Ibraheem, Muataz H. Alhashem, Fahad A. Al-Saab

Saudi Medical Journal

Objectives: To study is to establish the OM-6 scores in Saudi children with OME and subjectively assess the change in QoL following VT insertion. The Otitis Media 6 (OM-6) questionnaire is a widely used measure of the quality of life (QoL) in children with otitis media with effusion (OME). Myringotomy with ventilation tube (VT) insertion is indicated when OME persists with clinically documented hearing impairment. Methods: The present study is a prospective cohort study investigating the QoL of children with OME using a validated OM-6 questionnaire. The caregivers of 100 children were subjected to the questionnaire preoperatively from January 2023 …


Cochlear Implantation At King Abdallah Medical City, Makkah, Saudi Arabia: Single Institution Experience, A 5-Years Retrospective Analysis, Shatha Y. Alqahtani, Shuruq M. Almasoudi, Zohour A. Almalki, Khalid M. Badr, Saeed A. Alghamdi, Fares E. Alghamdi Feb 2025

Cochlear Implantation At King Abdallah Medical City, Makkah, Saudi Arabia: Single Institution Experience, A 5-Years Retrospective Analysis, Shatha Y. Alqahtani, Shuruq M. Almasoudi, Zohour A. Almalki, Khalid M. Badr, Saeed A. Alghamdi, Fares E. Alghamdi

Saudi Medical Journal

Objectives: To review the outcomes of the cochlear implantation program at King Abdallah Medical Center (KAMC) in Makkah from its launch in 2018 to 2023, focusing on patient demographics, procedural details, and complications. Methods: A retrospective analysis was conducted on 133 patients who underwent cochlear implantation (CI) at KAMC between May 2018 and June 2023. Data collected included demographics, hearing loss types, anatomical findings from imaging, types of CI devices, procedural challenges, and complications. Results: The average age of the patients was 9 years (108 months) with 56.4% males and 96.2% Saudi nationals. Most patients (50.4%) were from Makkah, and …


Shifting Sands: Unveiling The Changes In Respiratory Comorbidities And Fungal Pathogens In Saudi Arabia, Aiah M. Khateb, Fadwa S. Alofi, Mohammad A. Alturkostani, Abdullah Z. Almutairi Feb 2025

Shifting Sands: Unveiling The Changes In Respiratory Comorbidities And Fungal Pathogens In Saudi Arabia, Aiah M. Khateb, Fadwa S. Alofi, Mohammad A. Alturkostani, Abdullah Z. Almutairi

Saudi Medical Journal

Objectives: To investigate epidemiological changes in respiratory fungal infections (RFI), including fungal isolation and colonization, at one of the main centers in Medina. The incidence of RFI is rising due to an increase in the number of immunocompromised individuals, a higher prevalence of respiratory viral infections, and an aging population. Methods: A retrospective cross-sectional study was conducted by extracting data of patients with fungal-positive respiratory cultures from King Fahad Hospital (KFH), Al Madinah Al Munawwarah from 2013 to 2023. Results: A total of 352 episodes of fungal-positive cultures were identified in 79 patients, reflecting a 12-fold increase in RFI prevalence. …


Risk Factors For Depression Symptoms In Adolescents: A Population-Based Study, Dewinda Candrarukmi, Fitri Hartanto, Tunjung Wibowo, Hari W. Nugroho, Moh S. Anam, Braghmandita W. Indraswari, Qodri Santosa, Nazliah Hanum Feb 2025

Risk Factors For Depression Symptoms In Adolescents: A Population-Based Study, Dewinda Candrarukmi, Fitri Hartanto, Tunjung Wibowo, Hari W. Nugroho, Moh S. Anam, Braghmandita W. Indraswari, Qodri Santosa, Nazliah Hanum

Saudi Medical Journal

Objectives: To ascertain the prevalence of depressive symptoms and identify related risk factors among adolescents. Methods: A cross-sectional survey was carried out using an online questionnaire completed by 1,413 adolescents from Central Java and Yogyakarta Provinces، Indonesia. The validated Indonesian version of the Children’s Depression Inventory (CDI) was used to evaluate depressive symptoms. Results: Symptoms of depression were identified in 28.5% of participants. Multivariate analysis revealed important risk factors, including female gender (OR 3.962, 95% CI 2.684–5.849), having mother who is a housewife (OR 4.155, 95% CI 1.424–12.126) or works in labor/farming/self-employment (OR 3.665, 95% CI 1.216–11.051), residing with a …


Major General Dr. Ketab Al-Otaibi (1943- 2024) Feb 2025

Major General Dr. Ketab Al-Otaibi (1943- 2024)

Saudi Medical Journal

No abstract provided.


Giant Left Gastric Artery Aneurysm With Intrathoracic Extension, Ayhan Akcali, Bilal Ogan, Celal Buğra Sezen, Muzaffer Metin Feb 2025

Giant Left Gastric Artery Aneurysm With Intrathoracic Extension, Ayhan Akcali, Bilal Ogan, Celal Buğra Sezen, Muzaffer Metin

Saudi Medical Journal

ABSTRACT Splanchnic artery aneurysms, particularly those involving the left gastric artery, are infrequent occurrences and often lack noticeable symptoms, but their rupture involves a significant risk of mortality. We present a case involving an unruptured left gastric artery aneurysm (LGAA) that extended into the right hemithorax. This case report outlines the categorization, clinical manifestations, and diagnostic challenges associated with such aneurysms. Our findings could offer valuable insights for clinicians and radiologists when adopting a systematic approach for the early detection and management of LGAA.


Who Prequalifies Diagnostic Test To Support Safer Administration Of P. Vivax Malaria Treatments Feb 2025

Who Prequalifies Diagnostic Test To Support Safer Administration Of P. Vivax Malaria Treatments

Saudi Medical Journal

No abstract provided.