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Review Of Ventricular Septal Defect In South Western Saudi Arabia, Abdulmajid M. Almawazini, Ahmed H. Ghamdi, Jameel M. Ghamdi
Review Of Ventricular Septal Defect In South Western Saudi Arabia, Abdulmajid M. Almawazini, Ahmed H. Ghamdi, Jameel M. Ghamdi
Saudi Medical Journal
No abstract provided.
Ruptured Ovarian Granulosa Cell Tumor As A Cause Of Hemoperitoneum, Berna Dilbaz, Burak Karadag, Deniz Hizli, Serdar Dilbaz
Ruptured Ovarian Granulosa Cell Tumor As A Cause Of Hemoperitoneum, Berna Dilbaz, Burak Karadag, Deniz Hizli, Serdar Dilbaz
Saudi Medical Journal
No abstract provided.
Community Acquired Klebsiella Pneumoniae, K1 Serotype. Invasive Liver Abscess With Bacteremia And Endophthalmitis, Mushira A. Enani, Noura A. El-Khizzi
Community Acquired Klebsiella Pneumoniae, K1 Serotype. Invasive Liver Abscess With Bacteremia And Endophthalmitis, Mushira A. Enani, Noura A. El-Khizzi
Saudi Medical Journal
A community-acquired syndrome of cryptogenic invasive Klebsiella pneumoniae (K. pneumoniae) liver abscess (CIKPLA) has been emerging worldwide over the past 3 decades, particularly in Taiwan and Korea. It is caused by highly virulent hypermucoviscous, rmpA positive K. pneumoniae serotype K1. This condition occurs in predominantly diabetic persons with no underlying hepatobiliary disease. Metastatic infections of the brain, meninges, lungs, pleura, bones, soft tissues, and eyes are unique features of this syndrome. We report a laboratory-confirmed regulator of mucoid phenotype (rmp)A-positive, K1 serotype K. pneumoniae from Saudi Arabia in 2 diabetic native Saudis presenting with community acquired, invasive liver abscess complicated …
Medical Social Sciences. Their Potential Contributions To Medical Education Reforms In Saudi Arabia, Hussein M. Al-Borie
Medical Social Sciences. Their Potential Contributions To Medical Education Reforms In Saudi Arabia, Hussein M. Al-Borie
Saudi Medical Journal
This article emphasizes a holistic definition of health. It then introduces the concept of Medical social sciences, and drawing from the literature, argues for the inevitability of social sciences in medical education, especially in the health systems of developing countries including the Kingdom of Saudi Arabia (KSA). This is followed by a brief history of medical education in KSA, and an examination of some important social science issues. Finally, this article suggests how a holistic approach involving inputs from the social and behavioral sciences could be incorporated into undergraduate medical education to produce medical professionals who could better meet the …
Helicobacter Pylori Virulence Markers In Gastroduodenal Disorders. Detection Of Cytotoxin-Associated Gene A And Vacuolating Cytotoxin-Associated Gene A Genes In Saudi Patients, Abdulaziz S. Al-Khattaf
Helicobacter Pylori Virulence Markers In Gastroduodenal Disorders. Detection Of Cytotoxin-Associated Gene A And Vacuolating Cytotoxin-Associated Gene A Genes In Saudi Patients, Abdulaziz S. Al-Khattaf
Saudi Medical Journal
OBJECTIVE: To detect the presence of virulence markers cytotoxin-associated (cagA) and vacuolating cytotoxin-associated (vacA) genes in gastric biopsy specimens of patients with gastroduodenal disorders. METHODS: This study was conducted at the Department of Pathology, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between March 2008 and February 2009. A total of 118 gastric biopsy specimens from 81 males and 37 females (mean age: 55 ± 18 years) with histological evidence for the presence of Helicobacter pylori (H. pylori) were included in the study. The H. pylori cagA and vacA genes were detected using polymerase chain reaction-enzyme-linked immunosorbent assay technique. …
Effect Of Acrylamide On Testis Of Albino Rats. Ultrastructure And Dna Cytometry Study, Hesham N. Mustafa
Effect Of Acrylamide On Testis Of Albino Rats. Ultrastructure And Dna Cytometry Study, Hesham N. Mustafa
Saudi Medical Journal
OBJECTIVE: To explore the harmful effects of acrylamide on the structure of testis in albino rats, in an attempt to clarify its potential risks on human health. METHODS: The present study was carried out in the Department of Anatomy, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia from December 2010 to December 2011. Forty-eight adult male albino rats (250-300 g) were divided randomly into 6 groups. Electron microscopy and histochemical techniques using Feulgen stain were used to conduct the morphological study. In addition, DNA cytometry method was used. RESULTS: Rats treated with acrylamide 25 mg/kg body weight …
Biomechanical Comparison Of Internal Fixations In Osteoporotic Intertrochanteric Fracture. A Finite Element Analysis, Gao-Xiang Yuan, Yu-Hui Shen, Bo Chen, Wei-Bin Zhang
Biomechanical Comparison Of Internal Fixations In Osteoporotic Intertrochanteric Fracture. A Finite Element Analysis, Gao-Xiang Yuan, Yu-Hui Shen, Bo Chen, Wei-Bin Zhang
Saudi Medical Journal
OBJECTIVE: To compare the biomechanical characteristics of dynamic hip screw (DHS) and proximal femoral nail anti-rotation (PFNA) for the treatment of 3 types of osteoporotic femoral intertrochanteric fracture (OFIF) by modeling, and virtual reduction with finite element analysis, and to provide some theoretical basis and reference to select the best internal fixation for clinical treatment of OFIF. METHODS: The experiment was conducted at the Laboratory of Biomechanics, Shanghai Institute of Orthopedics and Traumatology, Shanghai Jiaotong University School of Medicine, Shanghai, People9s Republic of China from February to December 2011. The CT scan was performed in 3 cases with different types …
Vitamin D Insufficiency And Treatment With Oral Vitamin D3 In Children With Chronic Kidney Disease, Jameela A. Kari, Sherif M. Eldesoky, Osama T. Bagdadi
Vitamin D Insufficiency And Treatment With Oral Vitamin D3 In Children With Chronic Kidney Disease, Jameela A. Kari, Sherif M. Eldesoky, Osama T. Bagdadi
Saudi Medical Journal
OBJECTIVE: To investigate the effects of oral cholecalciferol on the levels of vitamin D3 and intact parathyroid hormone (iPTH) in children with chronic kidney disease (CKD). METHODS: We conducted a prospective uncontrolled observational study at the Pediatric Nephrology Clinic of King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia between January and October 2011 to assess serum 25-hydroxyvitamin D3 (25[OH]D) and iPTH in children with CKD stages 2-5. Children with low vitamin D3 levels were commenced on cholecalciferol, 2000 IU/day. Their 25(OH)D3 and iPTH levels were reassessed, first after 3 months, and then after 6 months. Data analysis was performed …
Antimicrobial Susceptibility Patterns Of Multidrug-Resistant Pseudomonas Aeruginosa And Acinetobacter Baumannii Against Carbapenems, Colistin, And Tigecycline, Ali M. Somily, Muhammad M. Absar, Muhammad Z. Arshad, Zahid A. Shakoor, Amal J. Fatani, Yunus M. Siddiqui, Thomas S. Murray
Antimicrobial Susceptibility Patterns Of Multidrug-Resistant Pseudomonas Aeruginosa And Acinetobacter Baumannii Against Carbapenems, Colistin, And Tigecycline, Ali M. Somily, Muhammad M. Absar, Muhammad Z. Arshad, Zahid A. Shakoor, Amal J. Fatani, Yunus M. Siddiqui, Thomas S. Murray
Saudi Medical Journal
OBJECTIVE: To examine susceptibility of Pseudomonas aeruginosa (P. aeruginosa) and Acinetobacter baumannii (A. baumannii ) against carbapenems along with colistin and tigecycline as alternative therapeutic options. METHODS: A total of 117 strains of multidrug-resistant (MDR) non-fermenting Gram negative bacteria isolated from non-duplicate samples were collected consecutively. We included one sample from each patient (84 isolates of A. baumannii and 33 isolates of P. aeruginosa isolated from patients seen at King Khalid University Hospital, Riyadh, Saudi Arabia, from June to December 2010). Isolates were identified by the MicroScan WalkAway 96 Plus system. The minimum inhibitory concentrations (MICs) were determined by E-test …
Effectiveness Of Pharmaceutical Care In An Intensive Care Unit From China. A Pre- And Post-Intervention Study, Sai-Ping Jiang, Xia Zheng, Xin Li, Xiao-Yang Lu
Effectiveness Of Pharmaceutical Care In An Intensive Care Unit From China. A Pre- And Post-Intervention Study, Sai-Ping Jiang, Xia Zheng, Xin Li, Xiao-Yang Lu
Saudi Medical Journal
OBJECTIVE: To describe the development and implementation of pharmaceutical care services in an in-patient setting, and to examine the effectiveness of pharmacist interventions. METHODS: A single-center, 2-phase (pre-/post-intervention phase) design was performed in an intensive care unit (ICU) of a university-affiliated hospital. Patients in the post-intervention phase (March 2011 to June 2011) received pharmaceutical care from a clinical pharmacist, while patients in the pre-intervention phase (December 2010 to March 2011) received routine medical care. The pre- and post-intervention phases were then compared to evaluate the outcomes of pharmacist interventions. RESULTS: During the 3-month study period, the clinical pharmacist made 232 …
Patients' Preferences For Physicians' Attire In Saudi Arabia, Mohammed O. Al-Ghobain, Turki M. Al-Drees, Muhannad S. Alarifi, Hala M. Al-Marzoug, Waleed A. Al-Humaid, Abdulaziz M. Asiry
Patients' Preferences For Physicians' Attire In Saudi Arabia, Mohammed O. Al-Ghobain, Turki M. Al-Drees, Muhannad S. Alarifi, Hala M. Al-Marzoug, Waleed A. Al-Humaid, Abdulaziz M. Asiry
Saudi Medical Journal
OBJECTIVE: To assess Saudi patients9 preferences regarding Saudi physicians9 attire, and its influence on patients9 level of trust and confidence in their physician. METHODS: A cross-sectional survey was conducted from May to June 2011 among patients waiting to be seen by their physicians from the outpatient medical clinics of King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia. Patients were asked multiple questions, which included their choice of preference regarding the attire of male and female physicians. Additionally, patients were asked questions related to their preferences regarding their physician9s gender, and the influence of physician9s appearance on patient confidence. RESULTS: …
Epidemiology Of Medico-Legal Litigations And Related Medical Errors In Central And Northern Saudi Arabia. A Retrospective Prevalence Study, Basem Y. Henary, Omar A. Al-Yahia, Saleh A. Al-Gabbany, Salah M. Al-Kharaz
Epidemiology Of Medico-Legal Litigations And Related Medical Errors In Central And Northern Saudi Arabia. A Retrospective Prevalence Study, Basem Y. Henary, Omar A. Al-Yahia, Saleh A. Al-Gabbany, Salah M. Al-Kharaz
Saudi Medical Journal
OBJECTIVE: To study medico-legal litigations and related medical errors in Central (Al-Qassim), and Northern (Hael) districts in the Kingdom of Saudi Arabia (KSA), and to identify types and causes of errors to reduce medical errors and patient harm. METHODS: This retrospective prevalence study was carried out between May 2010 and December 2011 to analyze medico-legal litigations in Al-Qassim and Hael districts that were investigated by the Al-Qassim Medico-Legal Committee, Al-Qassim, KSA. Final verdicts issued between 1992 and 2009 included 293 cases. RESULTS: The patient9s mean age was 29.5 years. Fifty-seven percent of the patients were females, and 92% were Saudis. …
Safety Of Intradermal Bacillus Calmette-Guerin Bcg Vaccine For Neonates In Eastern Saudi Arabia, Ahmed R. Alsuwaidi, Ahmed H. Al-Salem
Safety Of Intradermal Bacillus Calmette-Guerin Bcg Vaccine For Neonates In Eastern Saudi Arabia, Ahmed R. Alsuwaidi, Ahmed H. Al-Salem
Saudi Medical Journal
No abstract provided.
Knowledge On Adherence And Safety Of The Oral Contraceptive Pill In Saudi Women, Ghadeer K. Al-Shaikh, Ahmed Y. Mayet, Mashael K. Alshaikh, Amani F. Hamad, Mansour A. Mahmoud, Hisham S. Aljadhey
Knowledge On Adherence And Safety Of The Oral Contraceptive Pill In Saudi Women, Ghadeer K. Al-Shaikh, Ahmed Y. Mayet, Mashael K. Alshaikh, Amani F. Hamad, Mansour A. Mahmoud, Hisham S. Aljadhey
Saudi Medical Journal
OBJECTIVE: To assess knowledge regarding adherence and safety of oral contraceptive pills (OCP) in Saudi women. METHODS: We conducted a cross-sectional prospective study in an outpatient pharmacy at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia from April to September 2011. Participants were healthy women aged greater than or equal to 18 years with an OCP prescription for contraception. We used a validated questionnaire to assess their knowledge regarding adherence and safety of OCPs. RESULTS: Four hundred and sixty women participated. Most (79%) knew to take an extra pill if they missed one in less than 12 hours, but …
Repair Of Critical Size Bone Defects With Porous Poly(D,L-Lactide)/Nacre Nanocomposite Hollow Scaffold, Wen-De Xiao, Zhao-Ming Zhong, Yong-Zhi Tang, Zi-Xing Xu, Zhun Xu, Jian-Ting Chen
Repair Of Critical Size Bone Defects With Porous Poly(D,L-Lactide)/Nacre Nanocomposite Hollow Scaffold, Wen-De Xiao, Zhao-Ming Zhong, Yong-Zhi Tang, Zi-Xing Xu, Zhun Xu, Jian-Ting Chen
Saudi Medical Journal
OBJECTIVE: To generate a novel porous poly(D,L-lactide)/nacre nanocomposite hollow scaffold. METHODS: This study was performed in the Department of Spine Surgery, Southern Medical University, Guangzhou, China from September 2010 to September 2011. Nacre nanoparticles were prepared using a physical process and identified by x-ray diffraction and transmission electron microscopy, to generate a novel scaffold though the salt leaching processing technique. The morphology and structure properties of this scaffold were further investigated under scanning electron microscope and mechanical property testing. Additionally, the biological characteristics were evaluated by cell culture experiments in vitro. Thirty-six rabbits were randomly divided into 3 groups. The …
Hepatitis B Virus Genotypes And Subgenotypes In The Eastern Black Sea Region Of Turkey, Nese Kaklikkaya, Metin Sancaktar, Rahmet Guner, Celal K. Buruk, Iftihar Koksal, Ilknur Tosun, Faruk Aydin
Hepatitis B Virus Genotypes And Subgenotypes In The Eastern Black Sea Region Of Turkey, Nese Kaklikkaya, Metin Sancaktar, Rahmet Guner, Celal K. Buruk, Iftihar Koksal, Ilknur Tosun, Faruk Aydin
Saudi Medical Journal
OBJECTIVE: To determine the hepatitis B virus (HBV) genotypes and subgenotypes in patients with HBV infection in the Eastern Black Sea region of Turkey. METHODS: One hundred and thirty-seven patients9 samples collected over 5 years (January 2005 to January 2010) at Farabi Hospital in Karadeniz Technical University, Trabzon, Turkey were included in the study. All patients were positive for hepatitis B surface antigen (HBsAg) and HBV DNA. The HBV genotypes were determined by the polymerase chain reaction - restriction fragment length polymorphism (PCR-RFLP) method using an amplified segment of the pre-S region of HBV. RESULTS: One hundred and twenty-five of …
Encopresis In Children. Outcome And Predictive Factors Of Successful Management, Adnan A. Mohammed, Farag M. Mekael
Encopresis In Children. Outcome And Predictive Factors Of Successful Management, Adnan A. Mohammed, Farag M. Mekael
Saudi Medical Journal
OBJECTIVE: To elucidate our experience and outcome in the management of childhood encopresis, and to emphasize the factors that may predict successful management. METHODS: This prospective study was carried out between September 2003 and September 2011 in the Department of Pediatric Surgery, Al-Thoura Teaching Hospital, Al-Beida and Al-Butnan Medical Teaching Center, Tobruk, Libya. RESULTS: One hundred and thirty-two patients (117 male, 15 female) took part of the study. The male and female ratio was 7.8:1. The participants were patients aged 4-9 years. There were 30 (22.7%) patients between 4-5 years, 61 (46.2%) between 6-7 years, and 41 (31%) between 8-9 …
Gastroesophageal Reflux Disease In Infants. Myths And Misconceptions, Where Is The Evidence?, Ahmed A. Sarkhy
Gastroesophageal Reflux Disease In Infants. Myths And Misconceptions, Where Is The Evidence?, Ahmed A. Sarkhy
Saudi Medical Journal
Infantile gastroesophageal reflux (GER) is a common self-limited, physiological phenomenon. Infantile gastroesophageal reflux becomes pathological (gastroesophageal reflux disease [GERD]) when symptoms become more severe or are associated with complications such as failure to thrive or hematemesis. Though it is a very common condition, there are several misconceptions and myths on GER/GERD diagnosis and management. Inappropriate investigations are frequently requested and unnecessary medications are increasingly prescribed, particularly in infants with symptoms attributed to possible GER/GERD. Several therapeutic interventions are used widely in GERD management, although some evidence is either insufficient or controversial.
Bowel Function And Its Associated Variables In Saudi Adults. A Population Based Study, Ahmad M. Zubaidi, Nouf H. Al-Saud, Xena A. Al-Qahtani, Shaffi A. Shaik, Maha H. Abdulla, Khayal A. Al-Khayal, Omar A. Al-Obeed
Bowel Function And Its Associated Variables In Saudi Adults. A Population Based Study, Ahmad M. Zubaidi, Nouf H. Al-Saud, Xena A. Al-Qahtani, Shaffi A. Shaik, Maha H. Abdulla, Khayal A. Al-Khayal, Omar A. Al-Obeed
Saudi Medical Journal
OBJECTIVE: To study bowel patterns (function/habits) and its associated variables in an adult Saudi population. METHODS: In a cross sectional study, a 21-item questionnaire on bowel function (habits and frequency) was distributed to 10,000 high school students from all 5 regions of Riyadh City, Saudi Arabia, between February and April 2011. The randomly selected students, and 2 of their household or family members completed the questionnaire. Socio-demographic characteristics, eating habits, chronic diseases, and medications used were studied. RESULTS: Sixty-one percent (N=4918) were above the age of 16 years, of which 51.5% were males, and 88.1% were Saudis. It was observed …
Pattern Of Cervical Smear Abnormalities Using The Revised Bethesda System In A Tertiary Care Hospital In Western Saudi Arabia, Fadwa J. Altaf, Shagufta T. Mufti
Pattern Of Cervical Smear Abnormalities Using The Revised Bethesda System In A Tertiary Care Hospital In Western Saudi Arabia, Fadwa J. Altaf, Shagufta T. Mufti
Saudi Medical Journal
OBJECTIVE: To evaluate Pap smear (PS) diagnoses at a tertiary care hospital using the revised Bethesda system, and to compare the results with other similar studies. METHODS: We designed a retrospective study to review all PS from the Cytopathology Department of King Abdulaziz University Hospital, Jeddah, Saudi Arabia from January 2005 to December 2009. RESULTS: Of the 7297 cases reviewed, 1254 cases (17.3%) had epithelial cell abnormalities. The categories included: atypical squamous cell of undetermined significance (ASC-US) found in 9.3%, atypical squamous cell, cannot exclude high squamous intraepithelial lesion (ASC-H) in 0.8%, low grade squamous intraepithelial lesion (LSIL) in 2.7%, …
The Corrected Perinatal Mortality Rate. A Hospital-Based Study In Saudi Arabia, Nabeel S. Bondagji, Eman M. Kasim
The Corrected Perinatal Mortality Rate. A Hospital-Based Study In Saudi Arabia, Nabeel S. Bondagji, Eman M. Kasim
Saudi Medical Journal
OBJECTIVE: To determine the corrected perinatal mortality rate (PMR) in a single tertiary care center, and to test the effect of unbooked pregnancies on the PMR, and amalgamate the 2 to develop a new terminology known as the extended corrected PMR. METHODS: We conducted a retrospective cohort study of all women who delivered at King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia between January 2000 and December 2010. We recorded all cases of perinatal death and calculated the PMR per annum. The PMR was corrected for extreme prematurity and congenital anomalies. The unbooked cases were reported, and the PMR …
Associations Between Spontaneous Preterm Birth And Maternal-Newborn Abo Blood Phenotype Pairs, Sameer Y. Al-Abdi, Maryam A. Al-Aamri, Kamal I. Dabelah, Taher A. Mousa, Najeeb G. Al-Rahman, Hussien I. Bukhamsien
Associations Between Spontaneous Preterm Birth And Maternal-Newborn Abo Blood Phenotype Pairs, Sameer Y. Al-Abdi, Maryam A. Al-Aamri, Kamal I. Dabelah, Taher A. Mousa, Najeeb G. Al-Rahman, Hussien I. Bukhamsien
Saudi Medical Journal
OBJECTIVE: To study whether spontaneous preterm birth (SPB) is associated with maternal-newborn ABO blood phenotype pairs. METHODS: We conducted a retrospective case-control study in the Department of Pediatrics, King Abdulaziz Hospital, Al-Ahsa, Kingdom of Saudi Arabia. A total of 631 live singleton SPBs (less than 37 weeks) between August 2005 and May 2011 formed the case group. A total of 2,204 live singleton term births (greater than or equal to 37 weeks) between May 2008 and April 2009 formed the control group. We extracted data on the mothers and their newborns from our neonatal electronic database and delivery room log …
Association Between Diabetes Self-Care, Medication Adherence, Anxiety, Depression, And Glycemic Control In Type 2 Diabetes, Ayman A. Al-Hayek, Asirvatham A. Robert, Aus A. Alzaid, Hussam M. Nusair, Nariman S. Zbaidi, Muwafak H. Al-Eithan, Asirvatham E. Sam
Association Between Diabetes Self-Care, Medication Adherence, Anxiety, Depression, And Glycemic Control In Type 2 Diabetes, Ayman A. Al-Hayek, Asirvatham A. Robert, Aus A. Alzaid, Hussam M. Nusair, Nariman S. Zbaidi, Muwafak H. Al-Eithan, Asirvatham E. Sam
Saudi Medical Journal
No abstract provided.
Abnormalities Of The Face, Liver, Heart, And Eyes, Mohammed Y. Hasosah
Abnormalities Of The Face, Liver, Heart, And Eyes, Mohammed Y. Hasosah
Saudi Medical Journal
No abstract provided.
Length Of Stay Of Patients In Different Rehabilitation Programs. A Hospital Experience In Saudi Arabia, Ahmad Z. Qureshi, Maher S. Al-Jadid
Length Of Stay Of Patients In Different Rehabilitation Programs. A Hospital Experience In Saudi Arabia, Ahmad Z. Qureshi, Maher S. Al-Jadid
Saudi Medical Journal
No abstract provided.
Men's Knowledge And Attitude Towards Breast Cancer In Saudi Arabia. A Cross-Sectional Study, Samia M. Al-Amoudi, Hassan S. Abduljabbar
Men's Knowledge And Attitude Towards Breast Cancer In Saudi Arabia. A Cross-Sectional Study, Samia M. Al-Amoudi, Hassan S. Abduljabbar
Saudi Medical Journal
OBJECTIVE: To identify men9s knowledge and attitude towards early detection of breast cancer. METHODS: This cross-sectional study was conducted at the outpatient clinics of King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia. Five hundred and fifty participants were selected by systemic randomization. The distributed questionnaire included: demographics, knowledge and its source on breast cancer, beliefs and practice regarding breast self-examination (BSE), mammography, and difficulties that may prevent women from seeking medical help. The questionnaire was filled anonymously and in private. RESULTS: The response rate was 90.9%, and most were employees (63.2%). Physicians represented 43.4% of the source of knowledge, …
The Mechanism Of Lipid Raft Mediating Chemoresistance Of Cervical Cancer, Yan-Xiang Cheng, Min Hu, Liao Chen, Jin-Ling Huang, Liang-Bin Xia, Bin-Shu Li, Li-Mei Zhou, Li Hong
The Mechanism Of Lipid Raft Mediating Chemoresistance Of Cervical Cancer, Yan-Xiang Cheng, Min Hu, Liao Chen, Jin-Ling Huang, Liang-Bin Xia, Bin-Shu Li, Li-Mei Zhou, Li Hong
Saudi Medical Journal
OBJECTIVE: To investigate the mechanism of lipid raft mediating chemotherapy resistance in cervical cancer. METHODS: This experiment was carried out in the Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China from June 2010 to February 2011. Hela cells were divided into 6 groups: control group (Ctrl), cisplatin group (Cis), lipid raft interference agent group (MCD), NADPH oxidase inhibitor group (Apo), lipid raft interference agent combined with cisplatin group (MCD+Cis), and NADPH oxidase inhibitor combined with cisplatin group (Apo+Cis). After the cervical cancer cells were treated with a correspondent agent for 24 hours, the number of surviving cells …
Barriers To Feedback In Undergraduate Medical Education. Male Students' Perspective In Central Saudi Arabia, Ali I. Al-Haqwi, Abdullah M. Al-Wahbi, Hamza M. Abdulghani, Henk T. Van Der Molen
Barriers To Feedback In Undergraduate Medical Education. Male Students' Perspective In Central Saudi Arabia, Ali I. Al-Haqwi, Abdullah M. Al-Wahbi, Hamza M. Abdulghani, Henk T. Van Der Molen
Saudi Medical Journal
OBJECTIVE: To explore the views of undergraduate medical students regarding the presence and sources of barriers to effective feedback in their setting. METHODS: This cross-sectional study was conducted at the College of Medicine, Department of Medical Education, King Saud bin Abdul-Aziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia from April to June 2010. A self-administered questionnaire was used to explore the objectives of the study. RESULTS: One hundred and eighty-six male undergraduate medical students participated in this study. Approximately 45% indicated presence of barriers to effective feedback. These include: absence of a clear system of feedback; inadequate skills …
Depleted Uranium. Is It Potentially Involved In The Recent Upsurge Of Malignancies In Populations Exposed To War Dust?, Hamdi H. Shelleh
Depleted Uranium. Is It Potentially Involved In The Recent Upsurge Of Malignancies In Populations Exposed To War Dust?, Hamdi H. Shelleh
Saudi Medical Journal
Due to its extreme density, depleted Uranium (DU) has recently entered the warfare industry and became a major pollutant to the biosphere. Although DU is less radioactive than natural Uranium, it still retains all its chemical toxicity. Limited data exists regarding the long-term hazards of DU on humans, however, it is suspected to be a major toxic and mutagenic agent. Literature review reveals the scarcity of the World Health Organization9s knowledge regarding related DU-malignancies. Battlefield reports documented a steady rise of malignancies and newborn malformations after war, that is, leukemia in the Balkans, and congenital anomalies and Kaposi sarcoma (KS) …
Association Of Cluster Of Differentiation 36 Gene Variant Rs1761667 (G>A) With Metabolic Syndrome In Egyptian Adults, Nervana M. Bayoumy, Mohamed M. El-Shabrawi, Hamdi H. Hassan
Association Of Cluster Of Differentiation 36 Gene Variant Rs1761667 (G>A) With Metabolic Syndrome In Egyptian Adults, Nervana M. Bayoumy, Mohamed M. El-Shabrawi, Hamdi H. Hassan
Saudi Medical Journal
OBJECTIVE: To investigate the relationship between cluster of differentiation (CD)36 gene variant rs1761667 (G>A) and metabolic syndrome (MetS) and its components in Egyptian patients. METHODS: This case-control study was conducted on MetS patients attending Suez Canal University Hospital, Egypt from November 2010 to October 2011. Peripheral blood was collected from 100 patients and 100 healthy controls for DNA extraction. The single nucleotide polymorphism (SNP) CD36 gene rs1761667 (G>A) was genotyped using real-time polymerase chain reaction, and allele discrimination technique. RESULTS: Distribution of CD36 genotypes in the patient group was AA (n=25), AG (n=70), and GG (n=5) while in …