Digital Commons Network^™

El Marqués De Villeroy, Oráculo De La Razón De Estado. Una Traducción Española Con Escolios De Pedro Van Der Hammen, Adrian Izquierdo

Publications and Research

The translations of French historian and politique Pierre Matthieu fostered the circulation of ideas on the best practices of government and stimulated the introduction of political theories such as reason of state, political prudence and sovereignty at a moment when all Europe struggled to reconcile the interests of state and religion. Matthieu´s Remarques d’Estat et d’histoire sur la vie et les services de Monsieur de Villeroi (1618) were translated in 1624 by Pedro van der Hammen, and adapted to the particular Spanish context. In this paper we study how the translation and the illustrations by van der Hammen combine the …

Crowdsourcing As An Approach To Customer Relationship Building In Academic Libraries, Lisa A. Ellis, Aisha Pena

Publications and Research

Library initiatives to first-year students not only present an opportunity to offer information literacy instruction for student advancement but they also serve a key marketing function by communicating the library’s ongoing value and building customer relationships. Library orientation tours are an example of how to effectively market to first-year students. Combining peer-to-peer learning and user-generated content via social media known as crowdsourcing, Newman Library sponsored a contest challenging first-year students to create a video sharing a useful library tip. The contributions and benefits of this co-creation approach to fostering relationships are examined and the implications to strengthening other library-user bonds …

Wsq: The 1970s Editor's Note, Cynthia Chris, Matt Brim

Publications and Research

This Editor's Note introduces the WSQ issue "The 1970s," co-edited by Shelly Eversley and Michelle Habel-Pallan, which explores the decade of the 1970s, its dynamic social movements and radical cultural shifts, from the rapid boom in feminist publishing to the failure to pass the Equal Rights Amendment.

Opening Up The Dialogue Across Disciplines: Making Room For Inquiry And Creativity From Pre-Kindergarten Through University, Amanda Nicole Gulla, Limor Pinhasi-Vittorio, Alison Lehner-Quam

Publications and Research

Professional development with teachers, whether they are in pre-K-12 schools or in higher education, creates opportunities for discussions among teachers and teacher educators about how to find spaces for creativity and the imagination within the struc- ture of the Common Core State Standards, a set of national standards adopted on a state- by-state basis in the U.S. Two education faculty members and an education librarian from a large city university held workshops, bringing together university faculty in arts and humanities, science, mathematics and education, and pre-K-12 teachers to explore the potential for inquiry and creativity in the Common Core State …

Humanitarianism's History Of The Singular, Miriam Ticktin

Publications and Research

In “The New Universalism” Daniel Bertrand Monk and Andrew Herscher bring together global history and global humanitarianism to argue the emergence of a new (perverse) universal singular—a monadological refugee and form of refuge that threaten to efface both. By putting shelter and displacement side by side, they insightfully point us to different global patterns, such as the turn to the principle of the particular. Monk and Herscher read these patterns against the grain, offering us—almost in passing—a new history of humanitarianism.

Dna Methylation Dynamics Of Germinal Center B Cells Are Mediated By Aid, Pilar M. Dominguez, Matt Teater, Nyasha Chambwe, Matthias Kormaksson, David Redmon, Jennifer Ishii, Bao Vuong, Jayanta Chaudhuri, Ari Melnick, Aparna Vasanthakumar, Lucy A. Godley, F. Nina Papavasiliou, Oliver Elemento, Rita Shaknovich

Publications and Research

Changes in DNA methylation are required for the formation of germinal centers (GCs), but the mechanisms of such changes are poorly understood. Activation-induced cytidine deaminase (AID) has been recently implicated in DNA demethylation through its deaminase activity coupled with DNA repair. We investigated the epigenetic function of AID in vivo in germinal center B cells (GCBs) isolated from wild-type (WT) and AID-deficient (Aicda^−/−) mice. We determined that the transit of B cells through the GC is associated with marked locus-specific loss of methylation and increased methylation diversity, both of which are lost in Aicda^−/− animals. Differentially …

Water And Sanitation Hygiene Knowledge, Attitude, And Practices Among Household Members Living In Rural Setting Of India, Anjana Kuberan, Awnish Kumar Singh, Jyoti Bala Kasav, Satish Prasad, Krishna Mohan Surapaneni, Vandana Upadhyay, Ashish Joshi

Publications and Research

Background: Rural population in developing countries face water, sanitation, and hygiene-related health issues. To objectively highlight these issues, we studied the knowledge, attitude, and practices-related to drinking water and sanitation facilities among the rural population of Chennai, India.

Materials and Methods: A cross-sectional study was designed involving individuals over 18 years of age living in Thandalam village, Chennai, India. Basic information about sociodemographic profile and existing drinking water and sanitation related knowledge, attitude, and practices was collected using a modified version of previously validated questionnaire and analyzed.

Results: Forty-five percent of the participants were not following any methods of water …

The Nutrition And Dietetics Workforce Needs Skills And Expertise In The New York Metropolitan Area, Ann Gaba, Apoorva Srivastava, Chioma Amadi, Ashish Joshi

Publications and Research

Background: There is an increased demand in the Nutrition and Dietetics field which has fostered credentialing to ensure competent graduates. The objective of this study is to conduct an exploratory analysis to identify nutrition/dietetics workforce needs, skills and expertise in the New York metropolitan area as exemplified in position announcements over a 4 year period.

Methods: We recorded position announcements for jobs in nutrition and dietetics from the New York State Registered Dietitian Yahoo group, and the Hunter College Nutrition and Food Sciences student and alumni listserv (NFS-L) over a 4 year period. Keywords were identified using job categories defined …

A Protocol For Developing An Evaluation Framework For An Academic And Private-Sector Partnership To Assess The Impact Of Major Food And Beverage Companies’ Investments In Community Health In The United States, Terry T-K Huang, Emily Ferris, Rachel Crossley, Michelle Guillermin, Sergio Costa, John Cawley

Publications and Research

Public health leaders increasingly recognize the importance of multi-sector partnerships and systems approaches to address obesity. Public-private partnerships (PPP), which are joint ventures between government agencies and private sector entities, may help facilitate this process, but need to be delivered through comprehensive, transparent frameworks to maximize potential benefits and minimize potential risks for all partners. The City University of New York (CUNY) School of Public Health and the Healthy Weight Commitment Foundation (HWCF) propose to engage in a unique academic-private-sector research partnership to evaluate the impact and effectiveness of the food and beverage industry’s investment in obesity and hunger prevention …

Utilizing Dental Hygienists To Improve Health Outcomes In Long-Term Care, Diana V. Macri

Publications and Research

Poor oral health practices contribute to negative health outcomes for residents of long-term care facilities. The abundance of current information on the oral–systemic connection underscores the need for improved oral hygiene among all citizens but specifically for older adults, who face challenges for self-care due to sensory, mobility, endurance and cognitive deficits. Dental hygienists are oral disease prevention specialists and are trained to perform dental procedures that significantly improve a person’s oral health. Dental hygienists are legally permitted to provide many oral healthcare services to residents of long-term care facilities independent of dentist supervision or in collaborative agreements with dentists. …

Hpv.Edu Study Protocol: A Cluster Randomised Controlled Evaluation Of Education, Decisional Support And Logistical Strategies In School-Based Human Papillomavirus (Hpv) Vaccination Of Adolescents, S. Rachel Skinner, Cristyn Davies, Spring Cooper, Tanya Stoney, Helen Marshall, Jane Jones, Joanne Collins, Heidi Hutton, Adriana Parrella, Gregory Zimet, David G. Regan, Patti Whyte, Julia M. L. Brotherton, Peter Richmond, Kirsten Mccaffrey, Suzanne M. Garland, Julie Leask, Melissa Kang, Annette Braunack-Mayer, John Kaldor

Publications and Research

Background The National Human Papillomavirus (HPV) Vaccination Program in Australia commenced in 2007 for females and in 2013 for males, using the quadrivalent HPV vaccine (HPV 6,11,16,18). Thus far, we have demonstrated very substantial reductions in genital warts and in the prevalence of HPV among young Australian women, providing early evidence for the success of this public health initiative. Australia has a long history of school-based vaccination programs for adolescents, with comparatively high coverage. However, it is not clear what factors promote success in a school vaccination program. The HPV.edu study aims to examine: 1) student knowledge about HPV vaccination; …

Pili-Induced Clustering Of N. Gonorrhoeae Bacteria, Johannes Taktikos, Yen Ting Lin, Holger Stark, Nicolas Biais, Vasily Zaburdaev

Publications and Research

Type IV pili (Tfp) are prokaryotic retractable appendages known to mediate surface attachment, motility, and subsequent clustering of cells. Tfp are the main means of motility for Neisseria gonorrhoeae, the causative agent of gonorrhea. Tfp are also involved in formation of the microcolonies, which play a crucial role in the progression of the disease. While motility of individual cells is relatively well understood, little is known about the dynamics of N. gonorrhoeae aggregation. We investigate how individual N. gonorrhoeae cells, initially uniformly dispersed on flat plastic or glass surfaces, agglomerate into spherical microcolonies within hours. We quantify the clustering process …

(-)-Oleocanthal Rapidly And Selectively Induces Cancer Cell Death Via Lysosomal Membrane Permeabilization, Onica Legendre, Paul A. S. Breslin, David A. Foster

Publications and Research

(-)-Oleocanthal (OC), a phenolic compound present in extra-virgin olive oil (EVOO), has been implicated in the health benefits associated with diets rich in EVOO. We investigated the effect of OC on human cancer cell lines in culture and found that OC induced cell death in all cancer cells examined as rapidly as 30 minutes after treatment in the absence of serum. OC treatment of non-transformed cells suppressed their proliferation but did not cause cell death. OC induced both primary necrotic and apoptotic cell death via induction of lysosomal membrane permeabilization (LMP). We provide evidence that OC promotes LMP by inhibiting …

Vulnerable, Not Voiceless: Outsider Narrative In Advocacy Against Discriminatory Policing, Nicole Smith Futrell

Publications and Research

Activists and lawyers advocating for those who are targeted, arrested, and prosecuted as a result of aggressive policing practices are often the first to hear individual accounts of the dehumanizing treatment endured by vulnerable communities. Working on the front lines of the criminal justice system on a daily basis may cause advocates to regard these descriptions as commonplace, such that the transformative potential of a shared personal experience is overlooked. Critical race, practice-oriented, and narrative theory scholarship have long recognized the power of telling one’s story. These disciplines have explored how outsider narrative, or the articulated experience of groups subordinated …

Development Of A Technology-Based Behavioral Vaccine To Prevent Adolescent Depression: A Health System Integration Model, Benjamin W. Van Voorhees, Tracy Gladstone, Stephanie Cordel, Monika Marko-Holguin, William Beardslee, Sachiko Kuwabara, Mark Allan Kaplan, Joshua Fogel, Anne Diehl, Chris Hansen, Carl Bell

Publications and Research

Efforts to prevent depression have become a key health system priority. Currently, there is a high prevalence of depression among adolescents, and treatment has become costly due to the recurrence patterns of the illness, impairment among patients, and the complex factors needed for a treatment to be effective. Primary care may be the optimal location to identify those at risk by offering an Internet-based preventive intervention to reduce costs and improve outcomes. Few practical interventions have been developed. The models for Internet intervention development that have been put forward focus primarily on the Internet component rather than how the program …

'The Rhythm Of Our Time Is Jazz': Popular Entertainment During The Weimar Republic, Sharon L. Jordan

Publications and Research

“’The Rhythm of Our Time is Jazz’: Popular Entertainment during the Weimar Republic” examines the widespread interest and influential role held by American ragtime and jazz music throughout German culture from the 1910s until World War II. Many artists incorporated minstrel imagery as a potent indicator of their outsider status during this period or used new materials and rhythmic forms inspired by jazz to fully reflect the technological achievements and dynamic environment of the modern metropolis.

The Last Denton Conference, Barbara R. Walters

Publications and Research

No abstract provided.

The Walled Gardens Of Ebook Surveillance: A Brief Set Of Arguments Against Drm In Libraries, Alycia Sellie

Publications and Research

This piece outlines a few brief arguments against the inclusion of ebooks with DRM restrictions in libraries. These arguments center upon what the presence of these ebooks signifies to patrons about libraries today, and how librarians should avoid holding books with DRM within their collections. Ebooks with DRM require that users give up personal data in order to read. In addition, restricted ebooks are frustrating to users and makes them dislike the libraries that offer them. Finally, DRM surveillance is at odds with librarians’ professional commitments to protecting patron privacy.

Hidden In Plain Sight: The Story Of The Hunter College Collection Of Puerto Rican Graphic Arts, Sarah Laleman Ward

Publications and Research

The Hunter College Collection of Puerto Rican Graphic Arts includes over 150 works produced between 1954 and 1985 and represents the work of forty-one artists. It is illustrative of the growth of the printmaking tradition in Puerto Rico during the twentieth century. Acquired through a misappropriation of funds by a student group in the mid-1980s and ultimately purchased by and displayed in the college, the story of this collection raises important questions regarding institutional responsibility for the purchase and stewardship of art objects. Should art be collected if no plans are made for its maintenance and care?

Short Peptides In Minimalistic Biocatalyst Design, Krystyna L. Duncan, Rein V. Ulijn

Publications and Research

We review recent developments in the use of short peptides in the design of minimalistic biocatalysts focusing on ester hydrolysis. A number of designed peptide nanostructures are shown to have (modest) catalytic activity. Five features are discussed and illustrated by literature examples, including primary peptide sequence, nanosurfaces/scaffolds, binding pockets, multivalency and the presence of metal ions. Some of these are derived from natural enzymes, but others, such as multivalency of active sites on designed nanofibers, may give rise to new features not found in natural enzymes. Remarkably, it is shown that each of these design features give rise to similar …

Iberian Theater And Performance, Christopher B. Swift

Publications and Research

Medieval Iberian theater and performance maintains a peculiar status within, and between, performance and medieval disciplines. In theater studies, medieval Iberia has received minimal scholarly attention, and standard theater history textbooks contain only traces of Iberian material, if any at all. Despite the existence of Catalonian and Castilian archival materials that indicate performance traditions unique to the peninsula, scholars of Spanish literature (outside of the notable exceptions below) generally view Iberian medieval theater as an anomaly. One of the main reasons for this situation is that Iberian theater has yet to emerge fully from traditional historiographic parameters predicated upon the …

Finding Influential Spreaders From Human Activity Beyond Network Location, Byungjoon Min, Fredrik Liljeros, Hernán A. Makse

Publications and Research

Most centralities proposed for identifying influential spreaders on social networks to either spread a message or to stop an epidemic require the full topological information of the network on which spreading occurs. In practice, however, collecting all connections between agents in social networks can be hardly achieved. As a result, such metrics could be difficult to apply to real social networks. Consequently, a new approach for identifying influential people without the explicit network information is demanded in order to provide an efficient immunization or spreading strategy, in a practical sense. In this study, we seek a possible way for finding …

Elevated Hba1c Levels And The Accumulation Of Differentiated T Cells In Cmv+ Individuals, Jerrald L. Rector, G. Neil Thomas, Victoria E. Burns, Jennifer B. Dowd, Raphael M. Herr, Paul A. Moss, Marc N. Jarczok, Kristina Hoffman, Joachim E. Fischer, Jos A. Bosch

Publications and Research

Aims/hypothesis Biological ageing of the immune system, or immunosenescence, predicts poor health and increased mortality. A hallmark of immunosenescence is the accumulation of differentiated cytotoxic T cells (CD27−CD45RA+/−; or dCTLs), partially driven by infection with the cytomegalovirus (CMV). Immune impairments reminiscent of immunosenescence are also observed in hyperglycaemia, and in vitro studies have illustrated mechanisms by which elevated glucose can lead to increased dCTLs. This study explored associations between glucose dysregulation and markers of immunosenescence in CMV+ and CMV− individuals. Methods A cross-sectional sample of participants from an occupational cohort study (n = 1,103, mean age 40 years, 88% male) …

The Role Of Scleraxis In Fate Determination Of Mesenchymal Stem Cells For Tenocyte Differentiation, Yonghui Li, Melissa Ramcharan, Zuping Zhou, Daniel J. Leong, Takintope Akinbiyi, Robert Majeska, Hui B. Sun

Publications and Research

Mesenchymal stem cells (MSCs) are pluripotent cells that primarily differentiate into osteocytes, chondrocytes, and adipocytes. Recent studies indicate that MSCs can also be induced to generate tenocyte-like cells; moreover, MSCs have been suggested to have great therapeutic potential for tendon pathologies. Yet the precise molecular cascades governing tenogenic differentiation of MSCs remain unclear. We demonstrate scleraxis, a transcription factor critically involved in embryonic tendon development and formation, plays a pivotal role in the fate determination of MSC towards tenocyte differentiation. Using murine C3H10T1/2 pluripotent stem cells as a model system, we show scleraxis is extensively expressed in the early phase …

Positional Isomerism Markedly Affects The Growth Inhibition Of Colon Cancer Cells By Nosh-Aspirin: Cox Inhibition And Modeling☆, Federica Vannini, Mitali Chattopadhyay, Ravinder Kodela, Praveen P.N. Rao, Khosrow Kashfi

Publications and Research

We recently reported the synthesis of NOSH-aspirin, a novel hybrid that releases both nitric oxide (NO) and hydrogen sulfide (H2S). In NOSH-aspirin, the two moieties that release NO and H2S are covalently linked at the 1, 2 positions of acetyl salicylic acid, i.e. ortho-NOSH-aspirin (o-NOSH-aspirin). In the present study, we compared the effects of the positional isomers of NOSH-ASA (o-NOSH-aspirin, m-NOSH-aspirin and p-NOSH-aspirin) to that of aspirin on growth of HT-29 and HCT 15 colon cancer cells, belonging to the same histological subtype, but with different expression of cyclooxygenase (COX) enzymes; HT-29 express both COX-1 and COX-2, whereas HCT 15 …

Development Of A Clickable Bimodal Fluorescent/Pet Probe For In Vivo Imaging, Andreas Paulus, Pooja Desai, Brandon Carney, Giuseppe Carlucci, Thomas Reiner, Christian Brand, Wolfgang A. Weber

Publications and Research

Background Fluorescent imaging agents are becoming evermore important in preclinical and clinical research. They do, however, suffer from poor tissue penetration, which makes optical fluorescence imaging incompatible with whole-body imaging techniques. The design of novel bimodal PET active and fluorescent tracers could therefore combine the benefits of optical imaging with radioactively labeled imaging probes. Herein, we report the synthesis and evaluation of a clickable 18F-labeled fluorescent dye. Methods An azide-modified BODIPY-Fl dye could be successfully radio-labeled with 18F using an 18F/19F exchange reaction of the boron-fluoride core of the BODIPY dye to yield a clickable bimodal PET/fluorescent imaging tool. In …

Comparison Of The Nutrient Content Of Children’S Menu Items At Us Restaurant Chains, 2010–2014, Andrea L. Deierlein, Kay Peat, Luz Claudio

Publications and Research

Objective To determine changes in the nutritional content of children’s menu items at U.S. restaurant chains between 2010 and 2014. Methods The sample consisted of 13 sit down and 16 fast-food restaurant chains ranked within the top 50 US chains in 2009. Nutritional information was accessed in June-July 2010 and 2014. Descriptive statistics were calculated for nutrient content of main dishes and side dishes, as well as for those items that were added, removed, or unchanged during the study period. Results Nutrient content of main dishes did not change significantly between 2010 and 2014. Approximately one-third of main dishes at …

Nosh-Sulindac (Avt-18a) Is A Novel Nitric Oxide- And Hydrogen Sulfide-Releasing Hybrid That Is Gastrointestinal Safe And Has Potent Anti-Inflammatory, Analgesic, Antipyretic, Anti-Platelet, And Anti-Cancer Properties, Khosrow Kashfi, Mitali Chattopadhyay, Ravinder Kodela

Publications and Research

Sulindac is chemopreventive and has utility in patients with familial adenomatous polyposis; however, side effects preclude its long-term use. NOSH-sulindac (AVT-18A) releases nitric oxide and hydrogen sulfide, was designed to be a safer alternative. Here we compare the gastrointestinal safety, anti-inflammatory, analgesic, anti-pyretic, anti-platelet, and anti-cancer properties of sulindac and NOSH-sulindac administered orally to rats at equimolar doses. Gastrointestinal safety: 6 h post-administration, number/size of hemorrhagic lesions in stomachs were counted. Tissue samples were frozen for PGE2, SOD, and MDA determination. Anti-inflammatory: 1 h after drug administration, the volume of carrageenan-induced rat paw edemas was measured for 5 h. Anti-pyretic: …

Perceptions Of Violence In Morrisania (The Bronx), Sheyla A. Delgado, Jeffrey A. Butts, Laila Alsabahi

Publications and Research

The NYCCure study measured changes in violent norms and attitudes in areas of New York City operating Cure Violence programs. Respondents were men aged 18-30 from the Morrisania area of The Bronx.

Perceptions Of Violence In Bedford-Stuyvesant (Brooklyn), Sheyla A. Delgado, Jeffrey A. Butts, Laila Alsabahi

Publications and Research

The NYCCure study measured changes in violent norms and attitudes in areas of New York City operating Cure Violence programs. Respondents were men aged 18-30 from the Bedford-Stuyvesant (Bed-Stuy) area of Brooklyn.