Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Publications and Research

Discipline
Keyword
Publication Year
File Type

Articles 3391 - 3420 of 10369

Full-Text Articles in Entire DC Network

Burning Libraries: A Community Response, Thomas H. Mcgovern Dec 2018

Burning Libraries: A Community Response, Thomas H. Mcgovern

Publications and Research

Archaeology is increasingly seen as a global change science as well as a provider of community heritage resources. Rapid climate change is destroying archaeological sites at an unprecedented rate, and community- based response is urgently needed.


Estudio Contrastivo Intercultural De Las Funciones Retóricas De Las Citas: La Producción De Textos Académicos En El Nivel De Posgrado Escritos En Español E Inglés, David Sánchez-Jiménez Dec 2018

Estudio Contrastivo Intercultural De Las Funciones Retóricas De Las Citas: La Producción De Textos Académicos En El Nivel De Posgrado Escritos En Español E Inglés, David Sánchez-Jiménez

Publications and Research

The main objective of this research is to discover which rhetorical functions were used in the Master´s thesis writing written by eight (8) American and eight (8) Spanish postgraduates in their na-tive language. A computerized tex-tual analysis of the rhetorical func-tion of citation was used to study this phenomenon (Petrić, 2007). The results obtained from the re-search showed that the different cultural conventions in the thesis writing indicate that when com-pared with native Spanish writers, the American writers of English use the highest number of cita-tions, and write a relatively longer Introduction and Conclusion parts. On the other hand, the …


Immediate Neurophysiological Effects Of Transcranial Electrical Stimulation, Anli Liu, Mihály Vöröslakos, Gregory Kronberg, Simon Henin, Matthew R. Krause, Yu Huang, Alexander Opitz, Ashesh Mehta, Christopher C. Pack, Bart Krekelberg, Antal Berényi, Lucas C. Parra, Lucia Melloni, Orrin Devinsky, György Buzsáki Nov 2018

Immediate Neurophysiological Effects Of Transcranial Electrical Stimulation, Anli Liu, Mihály Vöröslakos, Gregory Kronberg, Simon Henin, Matthew R. Krause, Yu Huang, Alexander Opitz, Ashesh Mehta, Christopher C. Pack, Bart Krekelberg, Antal Berényi, Lucas C. Parra, Lucia Melloni, Orrin Devinsky, György Buzsáki

Publications and Research

Noninvasive brain stimulation techniques are used in experimental and clinical fields for their potential effects on brain network dynamics and behavior. Transcranial electrical stimulation (TES), including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), has gained popularity because of its convenience and potential as a chronic therapy. However, a mechanistic understanding of TES has lagged behind its widespread adoption. Here, we review data and modelling on the immediate neurophysiological effects of TES in vitro as well as in vivo in both humans and other animals. While it remains unclear how typical TES protocols affect neural activity, we …


Review Of Recent Nuclear Magnetic Resonance Studies Of Ion Transport In Polymer Electrolytes, Stephen Munoz, Steven Greenbaum Nov 2018

Review Of Recent Nuclear Magnetic Resonance Studies Of Ion Transport In Polymer Electrolytes, Stephen Munoz, Steven Greenbaum

Publications and Research

Current and future demands for increasing the energy density of batteries without sacrificing safety has led to intensive worldwide research on all solid state Li-based batteries. Given the physical limitations on inorganic ceramic or glassy solid electrolytes, development of polymer electrolytes continues to be a high priority. This brief review covers several recent alternative approaches to polymer electrolytes based solely on poly(ethyleneoxide) (PEO) and the use of nuclear magnetic resonance (NMR) to elucidate structure and ion transport properties in these materials.


Increased Excitability Induced In The Primary Motor Cortex By Transcranial Ultrasound Stimulation, Benjamin C. Gibson, Joseph L. Sanguinetti, Bashar W. Badran, Alfred B. Yu, Evan P. Klein, Christopher C. Abbott, Jeffrey T. Hansberger, Vincent P. Clark Nov 2018

Increased Excitability Induced In The Primary Motor Cortex By Transcranial Ultrasound Stimulation, Benjamin C. Gibson, Joseph L. Sanguinetti, Bashar W. Badran, Alfred B. Yu, Evan P. Klein, Christopher C. Abbott, Jeffrey T. Hansberger, Vincent P. Clark

Publications and Research

Background: Transcranial Ultrasound Stimulation (tUS) is an emerging technique that uses ultrasonic waves to noninvasively modulate brain activity. As with other forms of non-invasive brain stimulation (NIBS), tUS may be useful for altering cortical excitability and neuroplasticity for a variety of research and clinical applications. The effects of tUS on cortical excitability are still unclear, and further complications arise from the wide parameter space offered by various types of devices, transducer arrangements, and stimulation protocols. Diagnostic ultrasound imaging devices are safe, commonly available systems that may be useful for tUS. However, the feasibility of modifying brain activity with diagnostic tUS …


The Internationalization Of The Nonprofit Sector - Part 1: The Internationalization Of Domestic Nonprofits, John Casey Nov 2018

The Internationalization Of The Nonprofit Sector - Part 1: The Internationalization Of Domestic Nonprofits, John Casey

Publications and Research

Professor Casey describes how domestic nonprofits are becoming increasingly internationally focused. He highlights the influence that corporate foundations and corporate social responsibility programs are having as one of the drivers in this process.


Contextual Fear Memory Modulates Psd95 Phosphorylation, Ampar Subunits, Pkmζ And Pi3k Differentially Between Adult And Juvenile Rats, Roseanna M. Zanca, Shirley Sanay, Jorge A. Avila, Edgar Rodriguez, Harry N. Shair, Peter A. Serrano Nov 2018

Contextual Fear Memory Modulates Psd95 Phosphorylation, Ampar Subunits, Pkmζ And Pi3k Differentially Between Adult And Juvenile Rats, Roseanna M. Zanca, Shirley Sanay, Jorge A. Avila, Edgar Rodriguez, Harry N. Shair, Peter A. Serrano

Publications and Research

It is well known that young organisms do not maintain memories as long as adults, but the mechanisms for this ontogenetic difference are undetermined. Previous work has revealed that the α-amino-3-hydroxy-5-methyl-4isoxazolepropionic acidreceptor (AMPAr)subunits aretraffickedinto the synaptic membranefollowing memory retrieval in adults. Additionally, phosphorylated PSD-95-pS295 promotes AMPAr stabilization at the synapse. We investigated these plasticity related proteins as potential mediators in the differential contextual stress memory retrieval capabilities observed between adult and juvenile rats. Rats were assigned to either pedestal stress (1h) or no stress control (home cage). Each animal was placed alone in an open field for 5minat the base …


Equalization Of Four Cardiovascular Risk Algorithms After Systematic Recalibration: Individual-Participant Meta-Analysis Of 86 Prospective Studies, Lisa Pennells, Stephen Kaptoge, Angela Wood, Mike Sweeting, Xiaohui Zhao, Ian White, Stephen Burgess, Peter Willeit, Thomas Bolton, Karel G. M. Moons, Yvonne T. Van Der Schouw, Randi Selmer, Kay-Tee Khaw, Vilmundur Gudnason, Gerd Assman, Philippe Amouyel, Veikko Salomaa, Mika Kivimaki, Borge G. Nordestgaard, Michael J. Blaha, Lewis H. Kuller, Hermann Brenner, Richard F. Gillum, Christa Meisinger, Ian Ford, Matthew W. Knuiman, Annika Rosengren, Debbie A. Lawlor, Henry Volzke, Cyrus Cooper, Alejandro Marin Ibañez, Edoardo Casiglia, Jussi Kauhanen, Jackie A. Cooper, Beatriz Rodriguez, Johan Sundstrom, Elizabeth Barrett-Connor, Rachel Dankner, Paul J. Nietert, Karina W. Davidson, Robert B. Wallace, Dan G. Blazer, Cecilia Bjorkelund, Chiara Donfrancesco, Harlan M. Krumholz, Aulikki Nissinen, Barry R. Davis, Sean Coady, Peter H. Whincup, Torben Jorgensen, Pierre Ducimetiere, Maurizo Trevisan, Gunnar Engstrom, Carlos J. Crespo, Tom W. Meade, Marjolein Visser, Daan Kromhout, Stefan Kiechl, Makoto Daimon, Jackie F. Price, Agustin Gomez De La Camara, J. Wouter Jukema, Benoit Lamarche, Altan Onat, Leon A. Simons, Maryam Kavousi, Yoav Ben-Shlomo, John Gallacher, Jacqueline M. Dekker, Hisatomi Arima, Nawar Shara, Robert W. Tipping, Ronan Roussel, Eric J. Brunner, Wolfgang Koenig, Masaru Sakurai, Jelena Pavlovic, Ron T. Gansevoort, Dorothea Nagel, Uri Goldbourt, Elizabeth L. M. Barr, Luigi Palmieri, Inger Njolstad, Shinichi Sato, W. M. Monique Verschuren, Cherian V. Varghese, Ian Graham, Oyere Onuma, Philip Greenland, Mark Woodward, Majid Ezzati, Bruce M. Psaty, Naveed Sattar, Rod Jackson, Paul M. Ridker, Nancy R. Cook, Ralph B. D'Agostino Sr., Simone G. Thompson, John Danesh, Emanuele Di Angelantonio Nov 2018

Equalization Of Four Cardiovascular Risk Algorithms After Systematic Recalibration: Individual-Participant Meta-Analysis Of 86 Prospective Studies, Lisa Pennells, Stephen Kaptoge, Angela Wood, Mike Sweeting, Xiaohui Zhao, Ian White, Stephen Burgess, Peter Willeit, Thomas Bolton, Karel G. M. Moons, Yvonne T. Van Der Schouw, Randi Selmer, Kay-Tee Khaw, Vilmundur Gudnason, Gerd Assman, Philippe Amouyel, Veikko Salomaa, Mika Kivimaki, Borge G. Nordestgaard, Michael J. Blaha, Lewis H. Kuller, Hermann Brenner, Richard F. Gillum, Christa Meisinger, Ian Ford, Matthew W. Knuiman, Annika Rosengren, Debbie A. Lawlor, Henry Volzke, Cyrus Cooper, Alejandro Marin Ibañez, Edoardo Casiglia, Jussi Kauhanen, Jackie A. Cooper, Beatriz Rodriguez, Johan Sundstrom, Elizabeth Barrett-Connor, Rachel Dankner, Paul J. Nietert, Karina W. Davidson, Robert B. Wallace, Dan G. Blazer, Cecilia Bjorkelund, Chiara Donfrancesco, Harlan M. Krumholz, Aulikki Nissinen, Barry R. Davis, Sean Coady, Peter H. Whincup, Torben Jorgensen, Pierre Ducimetiere, Maurizo Trevisan, Gunnar Engstrom, Carlos J. Crespo, Tom W. Meade, Marjolein Visser, Daan Kromhout, Stefan Kiechl, Makoto Daimon, Jackie F. Price, Agustin Gomez De La Camara, J. Wouter Jukema, Benoit Lamarche, Altan Onat, Leon A. Simons, Maryam Kavousi, Yoav Ben-Shlomo, John Gallacher, Jacqueline M. Dekker, Hisatomi Arima, Nawar Shara, Robert W. Tipping, Ronan Roussel, Eric J. Brunner, Wolfgang Koenig, Masaru Sakurai, Jelena Pavlovic, Ron T. Gansevoort, Dorothea Nagel, Uri Goldbourt, Elizabeth L. M. Barr, Luigi Palmieri, Inger Njolstad, Shinichi Sato, W. M. Monique Verschuren, Cherian V. Varghese, Ian Graham, Oyere Onuma, Philip Greenland, Mark Woodward, Majid Ezzati, Bruce M. Psaty, Naveed Sattar, Rod Jackson, Paul M. Ridker, Nancy R. Cook, Ralph B. D'Agostino Sr., Simone G. Thompson, John Danesh, Emanuele Di Angelantonio

Publications and Research

Aims: There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after ‘recalibration’, a method that adapts risk algorithms to take account of differences in the risk characteristics of the populations being studied.

Methods & Results: Using individual-participant data on 360737 participants without CVD at baseline in 86 prospective studies from 22 countries, we compared the Framingham risk score (FRS), Systematic COronary Risk Evaluation (SCORE), pooled cohort equations (PCE), and Reynolds risk score (RRS). We calculated measures of risk discrimination and calibration, and …


Identification And Characterization Of Early Photoreceptor Cis-Regulatory Elements And Their Relation To Onecut1, Nathalie Jean-Charles, Diego F. Buenaventura, Mark M. Emerson Nov 2018

Identification And Characterization Of Early Photoreceptor Cis-Regulatory Elements And Their Relation To Onecut1, Nathalie Jean-Charles, Diego F. Buenaventura, Mark M. Emerson

Publications and Research

Background: Cone and rod photoreceptors are two of the primary cell types affected in human retinal disease. Potential strategies to combat these diseases are the use of gene therapy to rescue compromised photoreceptors or to generate new functional photoreceptors to replace those lost in the diseased retina. Cis-regulatory elements specific to cones, rods, or both types of photoreceptors are critical components of successful implementation of these two strategies. The purpose of this study was to identify and characterize the cell type specificity and activity of cis-regulatory elements active in developing photoreceptors.

Methods: Cis-regulatory elements were introduced into the developing chicken …


Book Review: Theory For The Working Sociologist, Joseph Van Der Naald Nov 2018

Book Review: Theory For The Working Sociologist, Joseph Van Der Naald

Publications and Research

No abstract provided.


Cryptic Diversity In The Mexican Highlands: Thousands Of Uce Loci Help Illuminate Phylogenetic Relationships, Species Limits And Divergence Times Of Montane Rattlesnakes (Viperidae: Crotalus ), Christopher Blair, Robert W. Bryson Jr, Charles W. Linkem, David Lazcano, John Klicka, John E. Mccormack Nov 2018

Cryptic Diversity In The Mexican Highlands: Thousands Of Uce Loci Help Illuminate Phylogenetic Relationships, Species Limits And Divergence Times Of Montane Rattlesnakes (Viperidae: Crotalus ), Christopher Blair, Robert W. Bryson Jr, Charles W. Linkem, David Lazcano, John Klicka, John E. Mccormack

Publications and Research

With the continued adoption of genome‐scale data in evolutionary biology comes the challenge of adequately harnessing the information to make accurate phylogenetic inferences. Coalescent‐based methods of species tree inference have become common, and concatenation has been shown in simulation to perform well, particularly when levels of incomplete lineage sorting are low. However, simulation conditions are often overly simplistic, leaving empiricists with uncertainty regarding analytical tools. We use a large ultraconserved element data set (>3,000 loci) from rattlesnakes of the Crotalus triseriatus group to delimit lineages and estimate species trees using concatenation and several coalescent‐based methods. Unpartitioned and partitioned maximum …


Association Of Exposure To Police Violence With Prevalence Of Mental Healthsymptoms Among Urban Residents In The United States, Jordan E. Devylder, Hyun-Jin Jun, Lisa Fedina, Daniel Coleman, Deidre Anglin, Courtney Cogburn, Bruce Link, Richard P. Barth Nov 2018

Association Of Exposure To Police Violence With Prevalence Of Mental Healthsymptoms Among Urban Residents In The United States, Jordan E. Devylder, Hyun-Jin Jun, Lisa Fedina, Daniel Coleman, Deidre Anglin, Courtney Cogburn, Bruce Link, Richard P. Barth

Publications and Research

Importance Police violence is reportedly widespread in the United States and may pose a significant risk to public mental health.

Objective To examine the association between 12-month exposure to police violence and concurrent mental health symptoms independent of trauma history, crime involvement, and other forms of interpersonal violence exposure.

Design, Setting, and Participants This cross-sectional, general population survey study of 1221 eligible adults was conducted in Baltimore, Maryland, and New York City, New York, from October through December 2017. Participants were identified through Qualtrics panels, an internet-based survey administration service using quota sampling.

Exposures Past 12-month exposure to police violence, …


Risk Factor And High-Risk Place Variations Across Different Robbery Targets In Denver, Colorado, Nathan T. Connealy, Eric L. Piza Nov 2018

Risk Factor And High-Risk Place Variations Across Different Robbery Targets In Denver, Colorado, Nathan T. Connealy, Eric L. Piza

Publications and Research

Purpose

Risk Terrain Modeling (RTM) has been effectively used to spatially diagnose risk for crimes such as robbery, aggravated assault, and gun violence. An important contribution is to consider how risk differs across individual crimes and different target types. This study tests four different robbery target types in unique models to examine the potential for variation across significant risk factors and high-risk locations.

Methods

Using the online diagnostic software RTMDx, individual robbery models were run for four robbery target types in Denver, Colorado: commercial (businesses), carjacking (driver/vehicle), residential (home/dwelling), and street (pedestrians). A conjunctive analysis of case configurations was also …


Programmable Time-Domain Digital-Coding Metasurface For Non-Linear Harmonic Manipulation And New Wireless Communication Systems, Jie Zhao, Xi Yang, Jun Yan Dai, Qiang Cheng, Xiang Li, Ning Hua Qi, Jun Chen Ke, Guo Dong Bai, Shuo Liu, Shi Jin, Andrea Alù, Tie Jun Cui Nov 2018

Programmable Time-Domain Digital-Coding Metasurface For Non-Linear Harmonic Manipulation And New Wireless Communication Systems, Jie Zhao, Xi Yang, Jun Yan Dai, Qiang Cheng, Xiang Li, Ning Hua Qi, Jun Chen Ke, Guo Dong Bai, Shuo Liu, Shi Jin, Andrea Alù, Tie Jun Cui

Publications and Research

Optical non-linear phenomena are typically observed in natural materials interacting with light at high intensities, and they benefit a diverse range of applications from communication to sensing. However, controlling harmonic conversion with high efficiency and flexibility remains a major issue in modern optical and radio-frequency systems. Here, we introduce a dynamic time-domain digital-coding metasurface that enables efficient manipulation of spectral harmonic distribution. By dynamically modulating the local phase of the surface reflectivity, we achieve accurate control of different harmonics in a highly programmable and dynamic fashion, enabling unusual responses, such as velocity illusion. As a relevant application, we propose and …


Radiation In Its Origin: Health Risks Resulting From Prolonged Exposure To Radon, Tetiana Soloviova, Evans Lespinasse Nov 2018

Radiation In Its Origin: Health Risks Resulting From Prolonged Exposure To Radon, Tetiana Soloviova, Evans Lespinasse

Publications and Research

Among non-smokers, radon is the number one cause of lung cancer, and the second cause of lung cancer overall, according to the Environmental Protection Agency. Radon cannot be detected through one's sense of sight, smell, hearing, taste or touch. The only way to detect it is by testing certain spaces or environments with specialized instruments. This radioactive gas is present in trace quantities in the earth and produced by decaying uranium. It enters buildings through cracks in walls, floors, construction joints or gaps around service pipes, electrical wires and sump pits. It emits heavy nuclear fragments of alpha particles (two …


Surface Acting, Emotional Exhaustion, And Employee Sabotage To Customers: Moderating Roles Of Quality Of Social Exchanges, Hui Zhang, Zhiqing E. Zhou, Yan Zhan, Chengbin Liu, Li Zhang Nov 2018

Surface Acting, Emotional Exhaustion, And Employee Sabotage To Customers: Moderating Roles Of Quality Of Social Exchanges, Hui Zhang, Zhiqing E. Zhou, Yan Zhan, Chengbin Liu, Li Zhang

Publications and Research

Using the conservation of resources theory and social exchange theory as our conceptual frameworks, the current study examined how employee surface acting relates to their sabotage to customers through the mediating role of emotional exhaustion and explored the moderating roles of coworker exchange (CWX) and leader-member exchange (LMX). We collected two-wave time-lagged data from 540 clinical nurses and found that emotional exhaustion mediated the positive relationship between surface acting and employee sabotage to customers. In addition, we found that CWX buffered the positive effect of surface acting on emotional exhaustion, while LMX buffered the positive effect of emotional exhaustion on …


The Anti-Fracking Movement And The Politics Of Rural Marginalization In Lithuania: Intersectionality In Environmental Justice, Diana Mincyte, Aiste Bartkiene Nov 2018

The Anti-Fracking Movement And The Politics Of Rural Marginalization In Lithuania: Intersectionality In Environmental Justice, Diana Mincyte, Aiste Bartkiene

Publications and Research

While the environmental justice perspective focuses on the unequal distribution of environmental risks and benefits across different groups based on race, class, or gender, intersectionality approaches avoid the use of a priori categories to examine marginalization. We argue that intersectionality can broaden the scope of environmental justice studies by examining interactive, historically grounded processes through which categories of difference are produced. To support this argument, we present an illustrative case of the movement in Lithuania that challenged Chevron’s plans to prospect shale resources for potential fracking. We conduct a narrative analysis of public discourses surrounding the formation of the movement …


Bad Bunny, Good Scapegoat: How 'El Conejo Malo' Is Stirring A 'Moral Panic' In Post-Hurricane Puerto Rico, Yarimar Bonilla Nov 2018

Bad Bunny, Good Scapegoat: How 'El Conejo Malo' Is Stirring A 'Moral Panic' In Post-Hurricane Puerto Rico, Yarimar Bonilla

Publications and Research

Article examines the Moral Panic around the music of trap artist Bad Bunny in Puerto Rico


Receiver-Initiated Handshaking Mac Based On Traffic Estimation For Underwater Sensor Networks, Yuan Dong, Lina Pu, Yu Luo, Zheng Peng, Haining Mo, Yun Meng, Yi Zhao, Yuzhi Zhang Nov 2018

Receiver-Initiated Handshaking Mac Based On Traffic Estimation For Underwater Sensor Networks, Yuan Dong, Lina Pu, Yu Luo, Zheng Peng, Haining Mo, Yun Meng, Yi Zhao, Yuzhi Zhang

Publications and Research

In underwater sensor networks (UWSNs), the unique characteristics of acoustic channels have posed great challenges for the design of medium access control (MAC) protocols. The long propagation delay problem has been widely explored in recent literature. However,the long preamble problem with acoustic modems revealed in real experiments brings new challenges to underwater MAC design. The overhead of control messages in handshaking-based protocols becomes significant due to the long preamble in underwater acoustic modems. To address this problem, we advocate the receiver-initiated handshaking method with parallel reservation to improve the handshaking efficiency. Despite some existing works along this direction, the data …


The Application Of Electric Cell-Substrate Impedance Sensing (Ecis) Biosensors, Xudong Zhang, Sunghoon Jang Nov 2018

The Application Of Electric Cell-Substrate Impedance Sensing (Ecis) Biosensors, Xudong Zhang, Sunghoon Jang

Publications and Research

Electric cell-substrate impedance sensing (ECIS) is a label-free and non-invasive technique for analyzing the activities and morphologies of cells. The ECIS sensors are able to measure the impedance spectroscopy of cells attaching on the sensor substrates. The cell activities and morphologies influence the measure impedance directly. Traditional toxicity analysis has complicated processes compared to biosensor-based analysis. In this study, the toxicity analysis was performed with biosensor based on ECIS technique. The experimental results show that the ECIS sensor is able to quickly distinguish the toxic and non-toxic substance.


Transcranial Direct Current Stimulation For Online Gamers: A Prospective Single-Arm Feasibility Study, Sang Hoon Lee, Jooyeon Jamie Im, Jin Kyoung Oh, Eun Kyoung Choi, Sujing Yoon, Marom Bikson, In-Uk Song, Hyeonseok Jeong, Yong-An Chung Nov 2018

Transcranial Direct Current Stimulation For Online Gamers: A Prospective Single-Arm Feasibility Study, Sang Hoon Lee, Jooyeon Jamie Im, Jin Kyoung Oh, Eun Kyoung Choi, Sujing Yoon, Marom Bikson, In-Uk Song, Hyeonseok Jeong, Yong-An Chung

Publications and Research

Aim: Excessive use of online games can have negative influences on mental health and daily functioning. Although the effects of transcranial direct current stimulation (tDCS) have been investigated for the treatment of addiction, it has not been evaluated for excessive online game use. This study aimed to investigate the feasibility and tolerability of tDCS over the dorsolateral prefrontal cortex (DLPFC) in online gamers. Methods: A total of 15 online gamers received 12 active tDCS sessions over the DLPFC (anodal left/cathodal right, 2 mA for 30 min, 3 times per week for 4 weeks). Before and after tDCS sessions, all …


Il-24 Promotes Apoptosis Through Camp-Dependent Pka Pathways In Human Breast Cancer Cells, Leah Persaud, Jason Mighty, Xuelin Zhong, Ashleigh Francis, Marifer Mendez, Hilal Muharam, Stephen M. Redenti, Dibash Das, Bertal Huseyin Aktas, Moira Sauane Nov 2018

Il-24 Promotes Apoptosis Through Camp-Dependent Pka Pathways In Human Breast Cancer Cells, Leah Persaud, Jason Mighty, Xuelin Zhong, Ashleigh Francis, Marifer Mendez, Hilal Muharam, Stephen M. Redenti, Dibash Das, Bertal Huseyin Aktas, Moira Sauane

Publications and Research

Interleukin 24 (IL-24) is a tumor-suppressing protein, which inhibits angiogenesis and induces cancer cell-specific apoptosis. We have shown that IL-24 regulates apoptosis through phosphorylated eukaryotic initiation factor 2 alpha (eIF2α) during endoplasmic reticulum (ER) stress in cancer. Although multiple stresses converge on eIF2α phosphorylation, the cellular outcome is not always the same. In particular, ER stress-induced apoptosis is primarily regulated through the extent of eIF2α phosphorylation and activating transcription factor 4 (ATF4) action. Our studies show for the first time that cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) activation is required for IL-24-induced cell death in a variety of …


Impact Of Fiber Parameters On Edfa And/Or Raman Amplified High-Spectral-Efficiency Coherent Wdm Transmissions, Lufeng Leng Nov 2018

Impact Of Fiber Parameters On Edfa And/Or Raman Amplified High-Spectral-Efficiency Coherent Wdm Transmissions, Lufeng Leng

Publications and Research

The impact of fiber properties is investigated for coherent systems employing polarization-division multiplexed high-level quadrature amplitude modulation, wavelength-division multiplexing, and erbium-doped fiber amplifier and/or distributed Raman amplification. This is done by comparing the performances of fiber links of various attenuation coefficients and effective areas via experimentally verified analytical methods. Results show that the excess noise, which originates at amplifiers compensating for the losses of filters and switches located between fiber spans, can weaken or even diminish the performance enhancement brought about by lowering the fiber attenuation coefficient, especially if distributed Raman amplification is employed. This leads to the difference in …


“College Material” Structural Care At A New York City Transfer School, C. Ray Borck Nov 2018

“College Material” Structural Care At A New York City Transfer School, C. Ray Borck

Publications and Research

Based on ethnographic research at Brooklyn Community High School (BCHS), a transfer high school in New York City I demonstrate that students narrate their educational histories in terms of their experience of care, or lack of care, from teachers. Contributing to research on student-teacher relationships, care, resilience and retention, I develop the concept structural care, arguing that teachers’ ability to demonstrate care for their students, and students’ ability to perceive that care, is enabled or constrained by larger, socio-structural forces such as the national educational policy landscape, widespread cultural beliefs about schools and students, and processes of racialization, criminalization, and …


Association Of The Haptoglobin Gene Polymorphism With Cognitive Function And Decline In Elderly African American Adults With Type 2 Diabetes: Findings From The Action To Control Cardiovascular Risk In Diabetes–Memory In Diabetes (Accord-Mind) Study, Michael Beeri, Hung-Mo Lin, Mary Sano, Ramit Ravona-Springer, Xiaoyu Liu, Barbara B. Bendlin, Carey E. Gleason, Elizabeth Guerrero-Berroa, Laili Soleimani, Lenore J. Launer, Scott Ehrenberg, Orit Lache, Yaakov K. Seligman, Andrew P. Levy Nov 2018

Association Of The Haptoglobin Gene Polymorphism With Cognitive Function And Decline In Elderly African American Adults With Type 2 Diabetes: Findings From The Action To Control Cardiovascular Risk In Diabetes–Memory In Diabetes (Accord-Mind) Study, Michael Beeri, Hung-Mo Lin, Mary Sano, Ramit Ravona-Springer, Xiaoyu Liu, Barbara B. Bendlin, Carey E. Gleason, Elizabeth Guerrero-Berroa, Laili Soleimani, Lenore J. Launer, Scott Ehrenberg, Orit Lache, Yaakov K. Seligman, Andrew P. Levy

Publications and Research

IMPORTANCE African American individuals have higher dementia risk than individuals of white race/ethnicity. They also have higher rates of type 2 diabetes, which may contribute to this elevated risk. This study examined the association of the following 2 classes of alleles at the haptoglobin (Hp) locus that are associated with poor cognition, cardiovascular disease, and mortality: Hp 1-1 (associated with poor cognition and cerebrovascular disease) and Hp 2-1 and Hp 2-2 (associated with greater risk ofmyocardial infarction and mortality). An additional polymorphism in the promoter region of the Hp 2 allele, restricted to individuals of African descent, yields a fourth …


The Mediating Role Of Health Consciousness In The Relation Between Emotional Intelligence And Health Behaviors, Adriana Espinosa, Selma Kadic-Maglajlic Nov 2018

The Mediating Role Of Health Consciousness In The Relation Between Emotional Intelligence And Health Behaviors, Adriana Espinosa, Selma Kadic-Maglajlic

Publications and Research

The goals of this study were to identify groups of health-related behaviors among young adults (N = 314, Mage = 21.94, SD = 6.53), gauge the relation between emotional intelligence and health behaviors in this population, and assess health consciousness as mediator of said relation. Latent class analysis identified two mutually exclusive health behavior groups, which according to response patterns were labeled as Healthy and Unhealthy.The Healthy group(56%)was composed of individuals who had a healthy diet (i.e.,low fat and high fiber),exercised regularly,and who frequently engaged in behaviors that prevent oral and skin-related diseases. In contrast, the Unhealthy group (44%) rarely …


Synthesis And Evaluation Of Troponoids As A New Class Of Antibiotics, Feng Cao, Cari Orth, Maureen J. Donlin, Patrick Adegboyega, Marvin J. Meyers, Ryan P. Murelli, Mohamed Elagawany, Bahaa Elgendy, John E. Tavis Nov 2018

Synthesis And Evaluation Of Troponoids As A New Class Of Antibiotics, Feng Cao, Cari Orth, Maureen J. Donlin, Patrick Adegboyega, Marvin J. Meyers, Ryan P. Murelli, Mohamed Elagawany, Bahaa Elgendy, John E. Tavis

Publications and Research

Novel antibiotics are urgently needed. The troponoids [tropones, tropolones, and α-hydroxytropolones (α-HT)] can have anti-bacterial activity. We synthesized or purchased 92 troponoids and evaluated their antibacterial activities against Staphylococcus aureus, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa. Preliminary hits were assessed for minimum inhibitory concentrations (MIC80) and cytotoxicity (CC50) against human hepatoma cells. Sixteen troponoids inhibited S. aureus/E. coli/ A. baumannii growth by ≥80% growth at <30 >μM with CC50 values >50 μM. Two selected tropolones (63 and 285) inhibited 18 methicillin-resistant S. aureus (MRSA) strains with similar MIC80 values as against a reference strain. Two selected thiotropolones (284 and 363) …


Voting For Secular Parties In The Middle East: Evidence From The 2014 General Elections In Post-Revolutionary Tunisia, H. Ege Ozen Nov 2018

Voting For Secular Parties In The Middle East: Evidence From The 2014 General Elections In Post-Revolutionary Tunisia, H. Ege Ozen

Publications and Research

Arab uprisings paved the way for democratic elections in the Middle East and

North Africa region. Yet countries in this region, except for Tunisia, were not

able to maintain further democratization. Tunisia, regardless of economic

turbulence and security problems, managed to hold its second parliamentary

elections in October 2014, and Ennahda, the party of the popular Islamist

movement, could not keep mass support. A large number of studies have

examined the rise of the Islamist parties as their electoral success in the post-

Arab Uprisings elections by focusing on their organizational strength as well

as their social services. However, the …


Poor Queer Studies: Class, Race, And The Field, Matt Brim Nov 2018

Poor Queer Studies: Class, Race, And The Field, Matt Brim

Publications and Research

This study asks, What are the material conditions under which queer studies is done in the academy? It finds a longstanding association of queer studies with the well-resourced, selective colleges and flagship campuses that are the drivers of class and race stratification in higher education in the U.S. That is, the field of queer studies, as a recognizable academic formation, has been structured by the material and intellectual resources of precisely those institutions that most steadfastly refuse to adequately serve poor and minority students, including poor and minority queer students. In response, “poor queer studies” calls for a critical reorientation …


Local Adaptation In Mainland Anole Lizards: Integrating Population History And Genome–Environment Associations, Ivan Prates, Anna Penna, Miguel Trefaut Rodrigues, Ana Carolina Carnaval Nov 2018

Local Adaptation In Mainland Anole Lizards: Integrating Population History And Genome–Environment Associations, Ivan Prates, Anna Penna, Miguel Trefaut Rodrigues, Ana Carolina Carnaval

Publications and Research

Environmental gradients constrain physiological performance and thus species’ ranges, suggesting that species occurrence in diverse environments may be associated with local adaptation. Genome–environment association analyses (GEAA) have become central for studies of local adaptation, yet they are sensitive to the spatial orientation of historical range expansions relative to landscape gradients. To test whether potentially adaptive genotypes occur in varied climates in wide‐ranged species, we implemented GEAA on the basis of genomewide data from the anole lizards Anolis ortonii and Anolis punctatus, which expanded from Amazonia, presently dominated by warm and wet settings, into the cooler and less rainy Atlantic …