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Walking For Leisure Among Adults From Three Brazilian Cities And Its Association With Perceived Environment Attributes And Personal Factors, Grace Ao Gomes, Rodrigo S. Reis, Diana C. Parra, Isabela Ribiero, Adriano Af Hino, Pedro C. Hallal, Deborah C. Malta, Ross C. Brownson Jan 2011

Walking For Leisure Among Adults From Three Brazilian Cities And Its Association With Perceived Environment Attributes And Personal Factors, Grace Ao Gomes, Rodrigo S. Reis, Diana C. Parra, Isabela Ribiero, Adriano Af Hino, Pedro C. Hallal, Deborah C. Malta, Ross C. Brownson

Open Access Publications

No abstract provided.


Demonstration Of An Online Tool To Assist Managed Care Formulary Evidence-Based Decision Making: Meta-Analysis Of Topical Prostaglandin Analog Efficacy, Steven M. Kymes, Caroline Burk, Todd Feinman, Julia M. Williams, David A. Hollander Jan 2011

Demonstration Of An Online Tool To Assist Managed Care Formulary Evidence-Based Decision Making: Meta-Analysis Of Topical Prostaglandin Analog Efficacy, Steven M. Kymes, Caroline Burk, Todd Feinman, Julia M. Williams, David A. Hollander

Open Access Publications

No abstract provided.


Bioluminescent Imaging Reveals Divergent Viral Pathogenesis In Two Strains Of Stat1-Deficient Mice, And In Αßγ Interferon Receptor-Deficient Mice, Tracy Jo Pasieka, Lynne Collins, Megan A. O'Connor, Yufei Chen, Zachary M. Parker, Brent L. Berwin, David R. Piwnica-Worms, David A. Leib Jan 2011

Bioluminescent Imaging Reveals Divergent Viral Pathogenesis In Two Strains Of Stat1-Deficient Mice, And In Αßγ Interferon Receptor-Deficient Mice, Tracy Jo Pasieka, Lynne Collins, Megan A. O'Connor, Yufei Chen, Zachary M. Parker, Brent L. Berwin, David R. Piwnica-Worms, David A. Leib

Open Access Publications

No abstract provided.


Genetic Variants In Lpl, Oasl And Tomm40/Apoe-C1-C2-C4 Genes Are Associated With Multiple Cardiovascular-Related Traits, Rita Ps Middelberg, Manuel Ar Ferreira, Anjali K. Henders, Andrew C. Heath, Pamela Af Madden, Grant W. Montgomery, Nicholas G. Martin, John B. Whitfield Jan 2011

Genetic Variants In Lpl, Oasl And Tomm40/Apoe-C1-C2-C4 Genes Are Associated With Multiple Cardiovascular-Related Traits, Rita Ps Middelberg, Manuel Ar Ferreira, Anjali K. Henders, Andrew C. Heath, Pamela Af Madden, Grant W. Montgomery, Nicholas G. Martin, John B. Whitfield

Open Access Publications

No abstract provided.


Investigation Of 95 Variants Identified In A Genome-Wide Study For Association With Mortality After Acute Coronary Syndrome, Thomas M. Morgan, John A. House, Sharon Cresci, Philip Jones, Hooman Allayee, Stanley L. Hazen, Yesha Patel, Riyaz S. Patel, Danny J. Eapen, Salina P. Waddy, Arshed A. Quyyumi, Marcus E. Kleber, Winfried Marz, Bernhard R. Winkelmann, Bernhard O. Boehm, Harlan M. Krumholz, John A. Spertus Jan 2011

Investigation Of 95 Variants Identified In A Genome-Wide Study For Association With Mortality After Acute Coronary Syndrome, Thomas M. Morgan, John A. House, Sharon Cresci, Philip Jones, Hooman Allayee, Stanley L. Hazen, Yesha Patel, Riyaz S. Patel, Danny J. Eapen, Salina P. Waddy, Arshed A. Quyyumi, Marcus E. Kleber, Winfried Marz, Bernhard R. Winkelmann, Bernhard O. Boehm, Harlan M. Krumholz, John A. Spertus

Open Access Publications

No abstract provided.


Magnetic Resonance Imaging Detects Significant Sex Differences In Human Myocardial Strain, Jennifer S. Lawton, Brian P. Cupps, Andrew K. Knutsen, Ningning Ma, Beckah D. Brady, Lina M. Reynolds, Michael K. Pasque Jan 2011

Magnetic Resonance Imaging Detects Significant Sex Differences In Human Myocardial Strain, Jennifer S. Lawton, Brian P. Cupps, Andrew K. Knutsen, Ningning Ma, Beckah D. Brady, Lina M. Reynolds, Michael K. Pasque

Open Access Publications

No abstract provided.


Principal Component Analysis Of Dynamic Relative Displacement Fields Estimated From Mr Images, Teresa M. Abney, Yuan Feng, Robert Pless, Ruth J. Okamoto, Guy M. Genin, Philip V. Bayly Jan 2011

Principal Component Analysis Of Dynamic Relative Displacement Fields Estimated From Mr Images, Teresa M. Abney, Yuan Feng, Robert Pless, Ruth J. Okamoto, Guy M. Genin, Philip V. Bayly

Open Access Publications

No abstract provided.


Astrovirus Mlb2 Viremia In Febrile Child, Lori R. Holtz, Kristine M. Wylie, Erica Sodergren, Yanfang Jiang, Carl J. Franz, George M. Weinstock, Gregory A. Storch, David Wang Jan 2011

Astrovirus Mlb2 Viremia In Febrile Child, Lori R. Holtz, Kristine M. Wylie, Erica Sodergren, Yanfang Jiang, Carl J. Franz, George M. Weinstock, Gregory A. Storch, David Wang

Open Access Publications

No abstract provided.


Manipulation Of Length And Lexicality Localizes The Functional Neuroanatomy Of Phonological Processing In Adult Readers, Jessica A. Church, David A. Balota, Steven E. Petersen, Bradley L. Schlaggar Jan 2011

Manipulation Of Length And Lexicality Localizes The Functional Neuroanatomy Of Phonological Processing In Adult Readers, Jessica A. Church, David A. Balota, Steven E. Petersen, Bradley L. Schlaggar

Open Access Publications

No abstract provided.


Prediction Error Associated With The Perceptual Segmentation Of Naturalistic Events, Jeffrey M. Zacks, Christopher A. Kurby, Michelle L. Eisenberg, Nayiri Haroutunian Jan 2011

Prediction Error Associated With The Perceptual Segmentation Of Naturalistic Events, Jeffrey M. Zacks, Christopher A. Kurby, Michelle L. Eisenberg, Nayiri Haroutunian

Open Access Publications

No abstract provided.


Phr1 Is Required For Proper Retinocollicular Targeting Of Nasal-Dorsal Retinal Ganglion Cells, Bradley Q. Vo, A J. Bloom, Susan M. Culican Jan 2011

Phr1 Is Required For Proper Retinocollicular Targeting Of Nasal-Dorsal Retinal Ganglion Cells, Bradley Q. Vo, A J. Bloom, Susan M. Culican

Open Access Publications

No abstract provided.


Laparoscopic Sleeve Gastrectomy Versus Laparoscopic Adjustable Gastric Banding For The Treatment Severe Obesity In High Risk Patients, J. Esteban Varela Jan 2011

Laparoscopic Sleeve Gastrectomy Versus Laparoscopic Adjustable Gastric Banding For The Treatment Severe Obesity In High Risk Patients, J. Esteban Varela

Open Access Publications

No abstract provided.


Early Toxicity Predicts Long-Term Survival In High-Grade Glioma, Yaacov R. Lawrence, Meihua Wang, Adam Paul Dicker, David W. Andrews, Walter John Curran, Jeff Michael Michalski, Luis Souhami, Alfred K. Yung, Minesh Mehta Jan 2011

Early Toxicity Predicts Long-Term Survival In High-Grade Glioma, Yaacov R. Lawrence, Meihua Wang, Adam Paul Dicker, David W. Andrews, Walter John Curran, Jeff Michael Michalski, Luis Souhami, Alfred K. Yung, Minesh Mehta

Open Access Publications

No abstract provided.


Long-Term Effects Of Multiple Glucocorticoid Exposures In Neonatal Mice, Susan E. Maloney, Kevin K. Noguchi, David F. Wozniak, Stephen C. Fowler, Nuri B. Farber Jan 2011

Long-Term Effects Of Multiple Glucocorticoid Exposures In Neonatal Mice, Susan E. Maloney, Kevin K. Noguchi, David F. Wozniak, Stephen C. Fowler, Nuri B. Farber

Open Access Publications

No abstract provided.


Genomic And Metabolic Profiling Of Nonulosonic Acids In Vibrionaceae Reveal Biochemical Phenotypes Of Allelic Divergence In Vibrio Vulnificus, Amanda L. Lewis, Jean-Bernard Lubin, Shilpa Argade, Natasha Naidu, Biswa Choudhury, E. Fidelma Boyd Jan 2011

Genomic And Metabolic Profiling Of Nonulosonic Acids In Vibrionaceae Reveal Biochemical Phenotypes Of Allelic Divergence In Vibrio Vulnificus, Amanda L. Lewis, Jean-Bernard Lubin, Shilpa Argade, Natasha Naidu, Biswa Choudhury, E. Fidelma Boyd

Open Access Publications

No abstract provided.


Card: A New Rna Polymerase Modulator In Mycobacteria, Christina L. Stallings, Michael S. Glickman Jan 2011

Card: A New Rna Polymerase Modulator In Mycobacteria, Christina L. Stallings, Michael S. Glickman

Open Access Publications

No abstract provided.


Cd103+ Pulmonary Dendritic Cells Preferentially Acquire And Present Apoptotic Cell-Associated Antigen, A Nicole Desch, Gwendalyn J. Randolph, Kenneth Murphy, Emmanuel L. Gautier, Ross M. Kedl, Mireille H. Lahoud, Irina Caminschi, Ken Shortman, Peter M. Henson, Claudia V. Jakubzick Jan 2011

Cd103+ Pulmonary Dendritic Cells Preferentially Acquire And Present Apoptotic Cell-Associated Antigen, A Nicole Desch, Gwendalyn J. Randolph, Kenneth Murphy, Emmanuel L. Gautier, Ross M. Kedl, Mireille H. Lahoud, Irina Caminschi, Ken Shortman, Peter M. Henson, Claudia V. Jakubzick

Open Access Publications

Cells undergoing programmed cell death (apoptosis) are removed in situ by macrophages and dendritic cells (DCs) through a specialized form of phagocytosis (efferocytosis). In the lung, there are two primary DC subsets with the potential to migrate to the local lymph nodes (LNs) and initiate adaptive immune responses. In this study, we show that only CD103(+) DCs were able to acquire and transport apoptotic cells to the draining LNs and cross present apoptotic cell-associated antigen to CD8 T cells. In contrast, both the CD11b(hi) and the CD103(+) DCs were able to ingest and traffic latex beads or soluble antigen. CD103(+) …


Type I Interferon Is Selectively Required By Dendritic Cells For Immune Rejection Of Tumors, Mark S. Diamond, Michelle Kinder, Hirokazu Matsushita, Mona Mashayekhi, Gavin P. Dunn, Jessica M. Archambault, Hsiaoju Lee, Cora D. Arthur, J Michael White, Ulrich Kalinke, Kenneth M. Murphy, Robert D. Schreiber Jan 2011

Type I Interferon Is Selectively Required By Dendritic Cells For Immune Rejection Of Tumors, Mark S. Diamond, Michelle Kinder, Hirokazu Matsushita, Mona Mashayekhi, Gavin P. Dunn, Jessica M. Archambault, Hsiaoju Lee, Cora D. Arthur, J Michael White, Ulrich Kalinke, Kenneth M. Murphy, Robert D. Schreiber

Open Access Publications

Cancer immunoediting is the process whereby the immune system suppresses neoplastic growth and shapes tumor immunogenicity. We previously reported that type I interferon (IFN-α/β) plays a central role in this process and that hematopoietic cells represent critical targets of type I IFN's actions. However, the specific cells affected by IFN-α/β and the functional processes that type I IFN induces remain undefined. Herein, we show that type I IFN is required to initiate the antitumor response and that its actions are temporally distinct from IFN-γ during cancer immunoediting. Using mixed bone marrow chimeric mice, we demonstrate that type I IFN sensitivity …


Do Shared Etiological Factors Contribute To The Relationship Between Sexual Orientation And Depression?, B. P. Zietsch, K. J H Verweij, A. C. Heath, P. A F Madden, N. G. Martin, E. C. Nelson, M. T. Lynskey Jan 2011

Do Shared Etiological Factors Contribute To The Relationship Between Sexual Orientation And Depression?, B. P. Zietsch, K. J H Verweij, A. C. Heath, P. A F Madden, N. G. Martin, E. C. Nelson, M. T. Lynskey

Open Access Publications

No abstract provided.


An Evolutionary Genomic Approach To Identify Genes Involved In Human Birth Timing, Jevon Plunkett, Scott Doniger, Guilherme Orabona, Thomas Morgan, Ritva Haataja, Mikko Hallman, Hilkka Puttonen, Ramkumar Menon, Edward Kuczynski, Errol Norwitz, Victoria Snegovskikh, Aarno Palotie, Leena Peltonen, Vineta Fellman, Emily A. Defranco, Bimal P. Chaudhari, Tracy L. Mcgregor, Jude J. Mcelroy, Matthew T. Oetjens, Kari Teramo, Ingrid Borecki, Justin Fay, Louis Muglia Jan 2011

An Evolutionary Genomic Approach To Identify Genes Involved In Human Birth Timing, Jevon Plunkett, Scott Doniger, Guilherme Orabona, Thomas Morgan, Ritva Haataja, Mikko Hallman, Hilkka Puttonen, Ramkumar Menon, Edward Kuczynski, Errol Norwitz, Victoria Snegovskikh, Aarno Palotie, Leena Peltonen, Vineta Fellman, Emily A. Defranco, Bimal P. Chaudhari, Tracy L. Mcgregor, Jude J. Mcelroy, Matthew T. Oetjens, Kari Teramo, Ingrid Borecki, Justin Fay, Louis Muglia

Open Access Publications

No abstract provided.


Dynamic Analysis Of Amyloid Β-Protein In Behaving Mice Reveals Opposing Changes In Isf Versus Parenchymal Aβ During Age-Related Plaque Formation, Soyon Hong, Omar Quintero-Monzon, Beth L. Ostaszewski, Daniel R. Podlisny, William T. Cavanaugh, Ting Yang, David M. Holtzman, John R. Cirrito, Dennis J. Selkoe Jan 2011

Dynamic Analysis Of Amyloid Β-Protein In Behaving Mice Reveals Opposing Changes In Isf Versus Parenchymal Aβ During Age-Related Plaque Formation, Soyon Hong, Omar Quintero-Monzon, Beth L. Ostaszewski, Daniel R. Podlisny, William T. Cavanaugh, Ting Yang, David M. Holtzman, John R. Cirrito, Dennis J. Selkoe

Open Access Publications

No abstract provided.


Micrornas Modulate Schwann Cell Response To Nerve Injury By Reinforcing Transcriptional Silencing Of Dedifferentiation-Related Genes, Andreu Viader, Li-Wei Chang, Timothy Fahrner, Rakesh Nagarajan, Jeffrey Milbrandt Jan 2011

Micrornas Modulate Schwann Cell Response To Nerve Injury By Reinforcing Transcriptional Silencing Of Dedifferentiation-Related Genes, Andreu Viader, Li-Wei Chang, Timothy Fahrner, Rakesh Nagarajan, Jeffrey Milbrandt

Open Access Publications

No abstract provided.


Behavioral State Modulates The Activity Of Brainstem Sensorimotor Neurons, Kimberly L. Mcarthur, J. David Dickman Jan 2011

Behavioral State Modulates The Activity Of Brainstem Sensorimotor Neurons, Kimberly L. Mcarthur, J. David Dickman

Open Access Publications

No abstract provided.


Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use As Imaging Ligands For Cerebral Amyloid Angiopathy, Byung Hee Han, Meng-Liang Zhou, Ananth K. Vellimana, Eric Milner, David H. Kim, Jacob K. Greenberg, Wenhua Chu, Robert H. Mach, Gregory J. Zipfel Jan 2011

Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use As Imaging Ligands For Cerebral Amyloid Angiopathy, Byung Hee Han, Meng-Liang Zhou, Ananth K. Vellimana, Eric Milner, David H. Kim, Jacob K. Greenberg, Wenhua Chu, Robert H. Mach, Gregory J. Zipfel

Open Access Publications

No abstract provided.


Type I Interferon Negatively Controls Plasmacytoid Dendritic Cell Numbers In Vivo, Melissa Swiecki, Yaming Wang, William Vermi, Susan Gilfillan, Robert D. Schreiber, Marco Colonna Jan 2011

Type I Interferon Negatively Controls Plasmacytoid Dendritic Cell Numbers In Vivo, Melissa Swiecki, Yaming Wang, William Vermi, Susan Gilfillan, Robert D. Schreiber, Marco Colonna

Open Access Publications

No abstract provided.


Memory B Cells, But Not Long-Lived Plasma Cells, Possess Antigen Specificities For Viral Escape Mutants, Whitney E. Purtha, Thomas F. Tedder, Syd Johnson, Deepta Bhattacharya, Michael S. Diamond Jan 2011

Memory B Cells, But Not Long-Lived Plasma Cells, Possess Antigen Specificities For Viral Escape Mutants, Whitney E. Purtha, Thomas F. Tedder, Syd Johnson, Deepta Bhattacharya, Michael S. Diamond

Open Access Publications

No abstract provided.


Midazolam Inhibits Hippocampal Long-Term Potentiation And Learning Through Dual Central And Peripheral Benzodiazepine Receptor Activation And Neurosteroidogenesis, Kazuhiro Tokuda, Kazuko A. O'Dell, Yukitoshi Izumi, Charles F. Zorumski Dec 2010

Midazolam Inhibits Hippocampal Long-Term Potentiation And Learning Through Dual Central And Peripheral Benzodiazepine Receptor Activation And Neurosteroidogenesis, Kazuhiro Tokuda, Kazuko A. O'Dell, Yukitoshi Izumi, Charles F. Zorumski

Open Access Publications

Benzodiazepines (BDZs) enhance GABA(A) receptor inhibition by direct actions on central BDZ receptors (CBRs). Although some BDZs also bind mitochondrial receptors [translocator protein (18 kDa) (TSPO)] and promote the synthesis of GABA-enhancing neurosteroids, the role of neurosteroids in the clinical effects of BDZs is unknown. In rat hippocampal slices, we compared midazolam, an anesthetic BDZ, with clonazepam, an anticonvulsant/anxiolytic BDZ that activates CBRs selectively. Midazolam, but not clonazepam, increased neurosteroid levels in CA1 pyramidal neurons without changing TSPO immunostaining. Midazolam, but not clonazepam, also augmented a form of spike inhibition after stimulation adjacent to the pyramidal cell layer and inhibited …


Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez Dec 2010

Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez

Open Access Publications

Cerebellar processing of incoming information begins at the synapse between mossy fibers and granule cells, a synapse that is strongly controlled through Golgi cell inhibition. Thus, Golgi cells are uniquely positioned to control the flow of information into the cerebellar cortex and understanding their responses during behavior is essential to understanding cerebellar function. Here we show, for the first time, that Golgi cells express a unique oculomotor-related signal that can be used to provide state- and time-specific filtering of granule cell activity. We used newly established criteria to identify the unique electrophysiological signature of Golgi cells and recorded these neurons …


The Contraceptive Choice Project: Recruiting Women At Highest Risk For Unintended Pregnancy And Sexually Transmitted Infection, Janine E. Spain, Jeffrey F. Peipert, Tessa Madden, Jenifer E. Allsworth, Gina M. Secura Nov 2010

The Contraceptive Choice Project: Recruiting Women At Highest Risk For Unintended Pregnancy And Sexually Transmitted Infection, Janine E. Spain, Jeffrey F. Peipert, Tessa Madden, Jenifer E. Allsworth, Gina M. Secura

Open Access Publications

No abstract provided.


Symptomatic Progression Of Asymptomatic Rotator Cuff Tears A Prospective Study Of Clinical And Sonographic Variables, Nathan A. Mall, H. Mike Kim, Jay D. Keener, Karen Steger-May, Sharlene A. Teefey, William D. Middleton, Georgia Stobbs, Ken Yamaguchi Nov 2010

Symptomatic Progression Of Asymptomatic Rotator Cuff Tears A Prospective Study Of Clinical And Sonographic Variables, Nathan A. Mall, H. Mike Kim, Jay D. Keener, Karen Steger-May, Sharlene A. Teefey, William D. Middleton, Georgia Stobbs, Ken Yamaguchi

Open Access Publications

No abstract provided.