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Articles 4891 - 4920 of 6228
Full-Text Articles in Entire DC Network
Exome Sequencing Identifies An Myh3 Mutation In A Family With Distal Arthrogryposis Type 1, David M. Alvarado, Jillian G. Buchan, Christina A. Gurnett, Matthew B. Dobbs
Exome Sequencing Identifies An Myh3 Mutation In A Family With Distal Arthrogryposis Type 1, David M. Alvarado, Jillian G. Buchan, Christina A. Gurnett, Matthew B. Dobbs
Open Access Publications
No abstract provided.
Role Of Guanylyl Cyclase Modulation In Mouse Cone Phototransduction, Keisuke Sakurai, Jeannie Chen, Vladimir J. Kefalov
Role Of Guanylyl Cyclase Modulation In Mouse Cone Phototransduction, Keisuke Sakurai, Jeannie Chen, Vladimir J. Kefalov
Open Access Publications
A negative phototransduction feedback in rods and cones is critical for the timely termination of their light responses and for extending their function to a wide range of light intensities. The calcium feedback mechanisms that modulate phototransduction in rods have been studied extensively. However, the corresponding modulation mechanisms that enable cones to terminate rapidly their light responses and to adapt in bright light, properties critical for our daytime vision, are still not understood. In cones, calcium feedback to guanylyl cyclase is potentially a key step in phototransduction modulation. The guanylyl cyclase activity is modulated by the calcium-binding guanylyl cyclase activating …
Biomedical And Psychosocial Factors Associated With Disability After Peripheral Nerve Injury, Christine B. Novak, Dimitri J. Anastakis, Dorcas E. Beaton, Susan E. Mackinnon, Joel Katz
Biomedical And Psychosocial Factors Associated With Disability After Peripheral Nerve Injury, Christine B. Novak, Dimitri J. Anastakis, Dorcas E. Beaton, Susan E. Mackinnon, Joel Katz
Open Access Publications
No abstract provided.
Evaluation Of The Toxicity Of Triamcinolone Acetonide And Dexamethasone Sodium Phosphate On Human Lens Epithelial Cells (Hle B-3), Ashish Sharma, Ashkan Pirouzmanesh, Jayaprakash Patil, M. F. Estrago-Franco, Leandro Cabral Zacharias, Usha P. Andley, M. Cristina Kenney, Baruch D. Kuppermann
Evaluation Of The Toxicity Of Triamcinolone Acetonide And Dexamethasone Sodium Phosphate On Human Lens Epithelial Cells (Hle B-3), Ashish Sharma, Ashkan Pirouzmanesh, Jayaprakash Patil, M. F. Estrago-Franco, Leandro Cabral Zacharias, Usha P. Andley, M. Cristina Kenney, Baruch D. Kuppermann
Open Access Publications
No abstract provided.
Incidence Of Symptomatic Venous Thromboembolism In Oncologic Patients Undergoing Lower-Extremity Endoprosthetic Arthroplasty, Brandon A. Ramo, Anthony M. Griffin, Corey S. Gill, Douglas J. Mcdonald, Jay S. Wunder, Peter Ferguson, Robert S. Bell, Sharon E. Phillips, Herbert S. Schwartz, Ginger E. Holt
Incidence Of Symptomatic Venous Thromboembolism In Oncologic Patients Undergoing Lower-Extremity Endoprosthetic Arthroplasty, Brandon A. Ramo, Anthony M. Griffin, Corey S. Gill, Douglas J. Mcdonald, Jay S. Wunder, Peter Ferguson, Robert S. Bell, Sharon E. Phillips, Herbert S. Schwartz, Ginger E. Holt
Open Access Publications
No abstract provided.
Clinical Presentation Of Symptomatic Acetabular Dysplasia In Skeletally Mature Patients, Ryan M. Nunley, Heidi Prather, Devyani Hunt, Perry L. Schoenecker, John C. Clohisy
Clinical Presentation Of Symptomatic Acetabular Dysplasia In Skeletally Mature Patients, Ryan M. Nunley, Heidi Prather, Devyani Hunt, Perry L. Schoenecker, John C. Clohisy
Open Access Publications
No abstract provided.
Radiographic Structural Abnormalities Associated With Premature, Natural Hip-Joint Failure, John C. Clohisy, Michael A. Dobson, Jason F. Robison, Lucian C. Warth, Jie Zheng, Steve S. Liu, Tameem M. Yehyawi, John J. Callaghan
Radiographic Structural Abnormalities Associated With Premature, Natural Hip-Joint Failure, John C. Clohisy, Michael A. Dobson, Jason F. Robison, Lucian C. Warth, Jie Zheng, Steve S. Liu, Tameem M. Yehyawi, John J. Callaghan
Open Access Publications
No abstract provided.
Managing Stress In The Orthopaedic Family: Avoiding Burnout, Achieving Resilience, M. Catherine Sargent, Wayne Sotile, Mary O. Sotile, Harry Rubash, Peter S. Vezeridis, Larry Harmon, Robert L. Barrack
Managing Stress In The Orthopaedic Family: Avoiding Burnout, Achieving Resilience, M. Catherine Sargent, Wayne Sotile, Mary O. Sotile, Harry Rubash, Peter S. Vezeridis, Larry Harmon, Robert L. Barrack
Open Access Publications
No abstract provided.
Congenital Bone Marrow Failure In Dna-Pkcs Mutant Mice Associated With Deficiencies In Dna Repair, Shichuan Zhang, Hirohiko Yajima, Hoangdinh Huynh, Junke Zheng, Elsa Callen, Hua-Tang Chen, Nancy Wong, Samuel Bunting, Yu-Fen Lin, Mengxia Li, Kyung-Jone Lee, Michael Story, Eric Gapud, Barry P. Sleckman, André Nussenzweig, Cheng Cheng Zhang, David J. Chen, Benjamin P.C. Chen
Congenital Bone Marrow Failure In Dna-Pkcs Mutant Mice Associated With Deficiencies In Dna Repair, Shichuan Zhang, Hirohiko Yajima, Hoangdinh Huynh, Junke Zheng, Elsa Callen, Hua-Tang Chen, Nancy Wong, Samuel Bunting, Yu-Fen Lin, Mengxia Li, Kyung-Jone Lee, Michael Story, Eric Gapud, Barry P. Sleckman, André Nussenzweig, Cheng Cheng Zhang, David J. Chen, Benjamin P.C. Chen
Open Access Publications
No abstract provided.
Long-Term Calorie Restriction, But Not Endurance Exercise, Lowers Core Body Temperature In Humans, Andreea Soare, Roberto Cangemi, Daniela Omodei, John O. Holloszy, Luigi Fontana
Long-Term Calorie Restriction, But Not Endurance Exercise, Lowers Core Body Temperature In Humans, Andreea Soare, Roberto Cangemi, Daniela Omodei, John O. Holloszy, Luigi Fontana
Open Access Publications
Reduction of body temperature has been proposed to contribute to the increased lifespan in calorie restricted animals and mice overexpressing the uncoupling protein-2 in hypocretin neurons. However, nothing is known regarding the long-term effects of calorie restriction (CR) with adequate nutrition on body temperature in humans. In this study, 24-hour core body temperature was measured every minute by using ingested telemetric capsules in 24 men and women (mean age 53.7 ± 9.4 yrs) consuming a CR diet for an average of 6 years, 24 age- and sex-matched sedentary (WD) and 24 body fat-matched exercise-trained (EX) volunteers, who were eating Western …
Episodic Memory Retrieval, Parietal Cortex, And The Default Mode Network: Functional And Topographic Analyses, Carlo Sestieri, Maurizio Corbetta, Gian Luca Romani, Gordon L. Shulman
Episodic Memory Retrieval, Parietal Cortex, And The Default Mode Network: Functional And Topographic Analyses, Carlo Sestieri, Maurizio Corbetta, Gian Luca Romani, Gordon L. Shulman
Open Access Publications
The default mode network (DMN) is often considered a functionally homogeneous system that is broadly associated with internally directed cognition (e.g., episodic memory, theory of mind, self-evaluation). However, few studies have examined how this network interacts with other networks during putative "default" processes such as episodic memory retrieval. Using functional magnetic resonance imaging, we investigated the topography and response profile of human parietal regions inside and outside the DMN, independently defined using task-evoked deactivations and resting-state functional connectivity, during episodic memory retrieval. Memory retrieval activated posterior nodes of the DMN, particularly the angular gyrus, but also more anterior and dorsal …
The Cytoplasmic Adaptor Protein Caskin Mediates Lar Signal Transduction During Drosophila Motor Axon Guidance, Yi-Lan Weng, Nan Liu, Aaron Diantonio, Heather T. Broihier
The Cytoplasmic Adaptor Protein Caskin Mediates Lar Signal Transduction During Drosophila Motor Axon Guidance, Yi-Lan Weng, Nan Liu, Aaron Diantonio, Heather T. Broihier
Open Access Publications
The multiprotein complexes that receive and transmit axon pathfinding cues during development are essential to circuit generation. Here, we identify and characterize the Drosophila sterile α-motif (SAM) domain-containing protein Caskin, which shares homology with vertebrate Caskin, a CASK [calcium/calmodulin-(CaM)-activated serine-threonine kinase]-interacting protein. Drosophila caskin (ckn) is necessary for embryonic motor axon pathfinding and interacts genetically and physically with the leukocyte common antigen-related (Lar) receptor protein tyrosine phosphatase. In vivo and in vitro analyses of a panel of ckn loss-of-function alleles indicate that the N-terminal SAM domain of Ckn mediates its interaction with Lar. Like Caskin, Liprin-α is a neuronal adaptor …
Myxoid Chondrosarcoma Of The Phalanx With An Ews Translocation: A Case Report And Review Of The Literature, David B. Bumpass, Michael Kyriakos, David A. Rubin, Paul R. Manske, Charles A. Goldfarb
Myxoid Chondrosarcoma Of The Phalanx With An Ews Translocation: A Case Report And Review Of The Literature, David B. Bumpass, Michael Kyriakos, David A. Rubin, Paul R. Manske, Charles A. Goldfarb
Open Access Publications
No abstract provided.
Are Dropped Osteoarticular Bone Fragments Safely Reimplantable In Vivo?, Benjamin Bruce, Shahin Sheibani-Rad, Deborah Appleyard, Ryan P. Calfee, Steven E. Reinert, Kimberle C. Chapin, Christopher W. Digiovanni
Are Dropped Osteoarticular Bone Fragments Safely Reimplantable In Vivo?, Benjamin Bruce, Shahin Sheibani-Rad, Deborah Appleyard, Ryan P. Calfee, Steven E. Reinert, Kimberle C. Chapin, Christopher W. Digiovanni
Open Access Publications
No abstract provided.
Renal Tumor Models: Evaluation Of Ease Of Implementation, Quality Of Composition, And Imaging Characteristics, Brian M. Benway, Jose M. Cabello, Alana C. Desai, Robert S. Figenshaw, Sam B. Bhayani
Renal Tumor Models: Evaluation Of Ease Of Implementation, Quality Of Composition, And Imaging Characteristics, Brian M. Benway, Jose M. Cabello, Alana C. Desai, Robert S. Figenshaw, Sam B. Bhayani
Open Access Publications
No abstract provided.
Effect Of Short-Duration Low-Magnitude Cyclic Loading Versus Immobilization On Tendon-Bone Healing After Acl Reconstruction In A Rat Model, Robert H. Brophy, David Kovacevic, Carl W. Imhauser, Mark Stasiak, Asheesh Bedi, Alice J.S. Fox, Xiang-Hua Deng, Scott A. Rodeo
Effect Of Short-Duration Low-Magnitude Cyclic Loading Versus Immobilization On Tendon-Bone Healing After Acl Reconstruction In A Rat Model, Robert H. Brophy, David Kovacevic, Carl W. Imhauser, Mark Stasiak, Asheesh Bedi, Alice J.S. Fox, Xiang-Hua Deng, Scott A. Rodeo
Open Access Publications
No abstract provided.
Nonuniform High-Gamma (60-500 Hz) Power Changes Dissociate Cognitive Task And Anatomy In Human Cortex, Charles M. Gaona, Mohit Sharma, Zachary V. Freudenburg, Jonathan D. Breshears, David T. Bundy, Jarod Roland, Dennis L. Barbour, Gerwin Schalk, Eric C. Leuthardt
Nonuniform High-Gamma (60-500 Hz) Power Changes Dissociate Cognitive Task And Anatomy In Human Cortex, Charles M. Gaona, Mohit Sharma, Zachary V. Freudenburg, Jonathan D. Breshears, David T. Bundy, Jarod Roland, Dennis L. Barbour, Gerwin Schalk, Eric C. Leuthardt
Open Access Publications
High-gamma-band (>60 Hz) power changes in cortical electrophysiology are a reliable indicator of focal, event-related cortical activity. Despite discoveries of oscillatory subthreshold and synchronous suprathreshold activity at the cellular level, there is an increasingly popular view that high-gamma-band amplitude changes recorded from cellular ensembles are the result of asynchronous firing activity that yields wideband and uniform power increases. Others have demonstrated independence of power changes in the low- and high-gamma bands, but to date, no studies have shown evidence of any such independence above 60 Hz. Based on nonuniformities in time-frequency analyses of electrocorticographic (ECoG) signals, we hypothesized that …
Calcium-Independent Inhibitory G-Protein Signaling Induces Persistent Presynaptic Muting Of Hippocampal Synapses, Devon C. Crawford, Chun Yun Chang, Krzysztof L. Hyrc, Steven Mennerick
Calcium-Independent Inhibitory G-Protein Signaling Induces Persistent Presynaptic Muting Of Hippocampal Synapses, Devon C. Crawford, Chun Yun Chang, Krzysztof L. Hyrc, Steven Mennerick
Open Access Publications
Adaptive forms of synaptic plasticity that reduce excitatory synaptic transmission in response to prolonged increases in neuronal activity may prevent runaway positive feedback in neuronal circuits. In hippocampal neurons, for example, glutamatergic presynaptic terminals are selectively silenced, creating "mute" synapses, after periods of increased neuronal activity or sustained depolarization. Previous work suggests that cAMP-dependent and proteasome-dependent mechanisms participate in silencing induction by depolarization, but upstream activators are unknown. We, therefore, tested the role of calcium and G-protein signaling in silencing induction in cultured hippocampal neurons. We found that silencing induction by depolarization was not dependent on rises in intracellular calcium, …
Changes In Events Alter How People Remember Recent Information, Khena M. Swallow, Deanna M. Barch, Denise Head, Corey J. Maley, Derek Holder, Jeffrey M. Zacks
Changes In Events Alter How People Remember Recent Information, Khena M. Swallow, Deanna M. Barch, Denise Head, Corey J. Maley, Derek Holder, Jeffrey M. Zacks
Open Access Publications
No abstract provided.
Representation Of Vestibular And Visual Cues To Self-Motion In Ventral Intraparietal Cortex, Aihua Chen, Gregory C. Deangelis, Dora E. Angelaki
Representation Of Vestibular And Visual Cues To Self-Motion In Ventral Intraparietal Cortex, Aihua Chen, Gregory C. Deangelis, Dora E. Angelaki
Open Access Publications
No abstract provided.
Statistical Analysis And Interpretation Of Prenatal Diagnostic Imaging Studies, Part 3: Approach To Study Design, Katherine R. Goetzinger, Methodius G. Tuuli, Anthony O. Odibo
Statistical Analysis And Interpretation Of Prenatal Diagnostic Imaging Studies, Part 3: Approach To Study Design, Katherine R. Goetzinger, Methodius G. Tuuli, Anthony O. Odibo
Open Access Publications
No abstract provided.
Nonlinear Interactions Between Excitatory And Inhibitory Retinal Synapses Control Visual Output, Botir T. Sagdullaev, Erika D. Eggers, Robert Purgert, Peter D. Lukasiewicz
Nonlinear Interactions Between Excitatory And Inhibitory Retinal Synapses Control Visual Output, Botir T. Sagdullaev, Erika D. Eggers, Robert Purgert, Peter D. Lukasiewicz
Open Access Publications
No abstract provided.
Primary Somatosensory Cortex In Chronic Low Back Pain – A 1h-Mrs Study, Neena K. Sharma, Kenneth Mccarson, Linda Van Dillen, Angela Lentz, Talal Khan, Carmen M. Cirstea
Primary Somatosensory Cortex In Chronic Low Back Pain – A 1h-Mrs Study, Neena K. Sharma, Kenneth Mccarson, Linda Van Dillen, Angela Lentz, Talal Khan, Carmen M. Cirstea
Open Access Publications
No abstract provided.
Ultrasound Is Safe. . . Right?: Resident And Maternal-Fetal Medicine Fellow Knowledge Regarding Obstetric Ultrasound Safety, Laura E. Houston, Jenifer Allsworth, George A. Macones
Ultrasound Is Safe. . . Right?: Resident And Maternal-Fetal Medicine Fellow Knowledge Regarding Obstetric Ultrasound Safety, Laura E. Houston, Jenifer Allsworth, George A. Macones
Open Access Publications
No abstract provided.
Inhibition Of Hypoxia-Induced Mir-155 Radiosensitizes Hypoxic Lung Cancer Cells, Imran A. Babar, Jennifer Czochor, Allison Steinmetz, Joanne B. Weidhaas, Peter M. Glazer, Frank J. Slack
Inhibition Of Hypoxia-Induced Mir-155 Radiosensitizes Hypoxic Lung Cancer Cells, Imran A. Babar, Jennifer Czochor, Allison Steinmetz, Joanne B. Weidhaas, Peter M. Glazer, Frank J. Slack
Open Access Publications
No abstract provided.
Daily Or Intermittent Budesonide In Preschool Children With Recurrent Wheezing, Leonard B. Bacharier, Robert C. Strunk, Avraham Beigelman, Et Al
Daily Or Intermittent Budesonide In Preschool Children With Recurrent Wheezing, Leonard B. Bacharier, Robert C. Strunk, Avraham Beigelman, Et Al
Open Access Publications
No abstract provided.
Four-Year Longitudinal Performance Of A Population-Based Sample Of Healthy Children On A Neuropsychological Battery: The Nih Mri Study Of Normal Brain Development, Deborah P. Waber, Peter W. Forbes, C. R. Almli, Emily A. Blood
Four-Year Longitudinal Performance Of A Population-Based Sample Of Healthy Children On A Neuropsychological Battery: The Nih Mri Study Of Normal Brain Development, Deborah P. Waber, Peter W. Forbes, C. R. Almli, Emily A. Blood
Open Access Publications
No abstract provided.
Strategic Manipulations For Associative Memory And The Role Of Verbal Processing Abilities In Schizophrenia, Aaron Bonner-Jackson, Deanna M. Barch
Strategic Manipulations For Associative Memory And The Role Of Verbal Processing Abilities In Schizophrenia, Aaron Bonner-Jackson, Deanna M. Barch
Open Access Publications
No abstract provided.
Regulation Of The Pmp22 Gene Through An Intronic Enhancer, Erin A. Jones, Camila Lopez-Anido, Rajini Srinivasan, Courtney Krueger, Li-Wei Chang, Rakesh Nagarajan, John Svaren
Regulation Of The Pmp22 Gene Through An Intronic Enhancer, Erin A. Jones, Camila Lopez-Anido, Rajini Srinivasan, Courtney Krueger, Li-Wei Chang, Rakesh Nagarajan, John Svaren
Open Access Publications
No abstract provided.
Neuronal Lrp1 Knockout In Adult Mice Leads To Impaired Brain Lipid Metabolism And Progressive, Age-Dependent Synapse Loss And Neurodegeneration, Qiang Liu, Justin Trotter, Juan Zhang, Melinda M. Peters, Hua Cheng, Jianxin Bao, Xianlin Han, Edwin J. Weeber, Guojun Bu
Neuronal Lrp1 Knockout In Adult Mice Leads To Impaired Brain Lipid Metabolism And Progressive, Age-Dependent Synapse Loss And Neurodegeneration, Qiang Liu, Justin Trotter, Juan Zhang, Melinda M. Peters, Hua Cheng, Jianxin Bao, Xianlin Han, Edwin J. Weeber, Guojun Bu
Open Access Publications
No abstract provided.