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An Rna Interference-Based Screen Of Transcription Factor Genes Identifies Pathways Necessary For Sensory Regeneration In The Avian Inner Ear, David M. Alvarado, R. D. Hawkins, Stavros Bashiardes, Rose A. Veile, Yuan-Chieh Ku, Kara E. Powder, Meghan K. Spriggs, Judith D. Speck, Mark E. Warchol, Michael Lovett Jan 2011

An Rna Interference-Based Screen Of Transcription Factor Genes Identifies Pathways Necessary For Sensory Regeneration In The Avian Inner Ear, David M. Alvarado, R. D. Hawkins, Stavros Bashiardes, Rose A. Veile, Yuan-Chieh Ku, Kara E. Powder, Meghan K. Spriggs, Judith D. Speck, Mark E. Warchol, Michael Lovett

Open Access Publications

No abstract provided.


Gateways Of Ventral And Dorsal Streams In Mouse Visual Cortex, Quanxin Wang, Enquan Gao, Andreas Burkhalter Jan 2011

Gateways Of Ventral And Dorsal Streams In Mouse Visual Cortex, Quanxin Wang, Enquan Gao, Andreas Burkhalter

Open Access Publications

No abstract provided.


Schwann Cell Mitochondrial Metabolism Supports Long-Term Axonal Survival And Peripheral Nerve Function, Andreu Viader, Judith P. Golden, Robert H. Baloh, Robert E. Schmidt, Daniel A. Hunter, Jeffrey Milbrandt Jan 2011

Schwann Cell Mitochondrial Metabolism Supports Long-Term Axonal Survival And Peripheral Nerve Function, Andreu Viader, Judith P. Golden, Robert H. Baloh, Robert E. Schmidt, Daniel A. Hunter, Jeffrey Milbrandt

Open Access Publications

No abstract provided.


Abnormal Presynaptic Short-Term Plasticity And Information Processing In A Mouse Model Of Fragile X Syndrome, Pan-Yue Deng, David Sojka, Vitaly A. Klyachko Jan 2011

Abnormal Presynaptic Short-Term Plasticity And Information Processing In A Mouse Model Of Fragile X Syndrome, Pan-Yue Deng, David Sojka, Vitaly A. Klyachko

Open Access Publications

No abstract provided.


Tissue And Stage-Specific Distribution Of Wolbachia In Brugia Malayi, Kerstin Fischer, Wandy L. Beatty, Daojun Jiang, Gary J. Weil, Peter U. Fischer Jan 2011

Tissue And Stage-Specific Distribution Of Wolbachia In Brugia Malayi, Kerstin Fischer, Wandy L. Beatty, Daojun Jiang, Gary J. Weil, Peter U. Fischer

Open Access Publications

No abstract provided.


Assessing The Optimal Definition Of Oligohydramnios Associated With Adverse Neonatal Outcomes, Anthony Shanks, Methodius Tuuli, Caren Schaecher, Anthony O. Odibo, Roxane Rampersad Jan 2011

Assessing The Optimal Definition Of Oligohydramnios Associated With Adverse Neonatal Outcomes, Anthony Shanks, Methodius Tuuli, Caren Schaecher, Anthony O. Odibo, Roxane Rampersad

Open Access Publications

No abstract provided.


The Genetic Sonogram: Comparing The Use Of Likelihood Ratios Versus Logistic Regression Coefficients For Down Syndrome Screening, Yan Zhong, Ryan Longman, Rachael Bradshaw, Anthony O. Odibo Jan 2011

The Genetic Sonogram: Comparing The Use Of Likelihood Ratios Versus Logistic Regression Coefficients For Down Syndrome Screening, Yan Zhong, Ryan Longman, Rachael Bradshaw, Anthony O. Odibo

Open Access Publications

No abstract provided.


Expression During Host Infection And Localization Of Yersinia Pestis Autotransporter Proteins, Jonathan D. Lenz, Matthew B. Lawrenz, David G. Cotter, M. Chelsea Lane, Rodrigo J. Gonzalez, Michelle Palacios, Virginia L. Miller Jan 2011

Expression During Host Infection And Localization Of Yersinia Pestis Autotransporter Proteins, Jonathan D. Lenz, Matthew B. Lawrenz, David G. Cotter, M. Chelsea Lane, Rodrigo J. Gonzalez, Michelle Palacios, Virginia L. Miller

Open Access Publications

No abstract provided.


Acute Impact Of Moderate-Intensity And Vigorous-Intensity Exercise Bouts On Daily Physical Activity Energy Expenditure In Postmenopausal Women, Xuewen Wang, Barbara J. Nicklas Jan 2011

Acute Impact Of Moderate-Intensity And Vigorous-Intensity Exercise Bouts On Daily Physical Activity Energy Expenditure In Postmenopausal Women, Xuewen Wang, Barbara J. Nicklas

Open Access Publications

No abstract provided.


Xenotransplantation Of Embryonic Pig Kidney Or Pancreas To Replace The Function Of Mature Organs, Marc R. Hammerman Jan 2011

Xenotransplantation Of Embryonic Pig Kidney Or Pancreas To Replace The Function Of Mature Organs, Marc R. Hammerman

Open Access Publications

No abstract provided.


Birth Characteristics And Childhood Carcinomas, Kimberly J. Johnson, Susan E. Carozza, Eric J. Chow, Erin E. Fox, Scott A. Horel, Colleen C. Mclaughlin, Beth A. Mueller, Susan E. Puumala, Peggy J. Reynolds, Julie Von Behren, Logan G. Spector Jan 2011

Birth Characteristics And Childhood Carcinomas, Kimberly J. Johnson, Susan E. Carozza, Eric J. Chow, Erin E. Fox, Scott A. Horel, Colleen C. Mclaughlin, Beth A. Mueller, Susan E. Puumala, Peggy J. Reynolds, Julie Von Behren, Logan G. Spector

Open Access Publications

No abstract provided.


Identification Of The Pgrmc1 Protein Complex As The Putative Sigma-2 Receptor Binding Site, Jinbin Xu, Chenbo Zeng, Wenhua Chu, Fenghui Pan, Justin M. Rothfuss, Fanjie Zhang, Zhude Tu, Dong Zhou, Dexing Zeng, Suwanna Vangveravong, Fabian Johnston, Dirk Spitzer, Katherine C. Chang, Richard S. Hotchkiss, William G. Hawkins, Robert H. Mach, Et Al Jan 2011

Identification Of The Pgrmc1 Protein Complex As The Putative Sigma-2 Receptor Binding Site, Jinbin Xu, Chenbo Zeng, Wenhua Chu, Fenghui Pan, Justin M. Rothfuss, Fanjie Zhang, Zhude Tu, Dong Zhou, Dexing Zeng, Suwanna Vangveravong, Fabian Johnston, Dirk Spitzer, Katherine C. Chang, Richard S. Hotchkiss, William G. Hawkins, Robert H. Mach, Et Al

Open Access Publications

No abstract provided.


Current Measures Of Metabolic Heterogeneity Within Cervical Cancer Do Not Predict Disease Outcome, Frank J. Brooks, Perry W. Grigsby Jan 2011

Current Measures Of Metabolic Heterogeneity Within Cervical Cancer Do Not Predict Disease Outcome, Frank J. Brooks, Perry W. Grigsby

Open Access Publications

No abstract provided.


Autophagy In Antigen-Presenting Cells Results In Presentation Of Citrullinated Peptides To Cd4 T Cells, Jamie M. Ireland, Emil R. Unanue Jan 2011

Autophagy In Antigen-Presenting Cells Results In Presentation Of Citrullinated Peptides To Cd4 T Cells, Jamie M. Ireland, Emil R. Unanue

Open Access Publications

Antibody responses to citrullinated self-proteins are found in autoimmunities, particularly in rheumatoid arthritis, where they serve as a diagnostic indicator. We show here that processing of the protein hen egg-white lysozyme (HEL) resulted in citrullination of peptides presented on class II MHC molecules by antigen-presenting cells. The presentation of the citrullinated peptides but not of the unmodified peptides was associated with autophagy. Dendritic cells (DCs), macrophages, and thymic DCs presented citrullinated peptides constitutively. Their treatment with 3-methyladenine (3MA) blocked presentation of citrullinated HEL peptides, but presentation of unmodified peptides was not affected. Presentation of citrullinated peptides was not detected on …


Barth Syndrome Mutations That Cause Tafazzin Complex Lability, Steven M. Claypool, Kevin Whited, Santi Srijumnong, Xianlin Han, Carla M. Koehler Jan 2011

Barth Syndrome Mutations That Cause Tafazzin Complex Lability, Steven M. Claypool, Kevin Whited, Santi Srijumnong, Xianlin Han, Carla M. Koehler

Open Access Publications

Deficits in mitochondrial function result in many human diseases. The X-linked disease Barth syndrome (BTHS) is caused by mutations in the tafazzin gene TAZ1. Its product, Taz1p, participates in the metabolism of cardiolipin, the signature phospholipid of mitochondria. In this paper, a yeast BTHS mutant tafazzin panel is established, and 18 of the 21 tested BTHS missense mutations cannot functionally replace endogenous tafazzin. Four BTHS mutant tafazzins expressed at low levels are degraded by the intermembrane space AAA (i-AAA) protease, suggesting misfolding of the mutant polypeptides. Paradoxically, each of these mutant tafazzins assembles in normal protein complexes. Furthermore, in the …


Cd2ap In Mouse And Human Podocytes Controls A Proteolytic Program That Regulates Cytoskeletal Structure And Cellular Survival, Andrey S. Shaw, Suma Yaddanapudi, Mehmet M. Altintas, Andreas D. Kistler, Isabel Fernandez, Clemens C. Moller, Changli Wei, Vasil Peev, Jan B. Flesche, Anna-Lena Forst, Jing Li, Jaakko Patrakka, Zhijie Xiao, Florian Grahammer, Et Al. Jan 2011

Cd2ap In Mouse And Human Podocytes Controls A Proteolytic Program That Regulates Cytoskeletal Structure And Cellular Survival, Andrey S. Shaw, Suma Yaddanapudi, Mehmet M. Altintas, Andreas D. Kistler, Isabel Fernandez, Clemens C. Moller, Changli Wei, Vasil Peev, Jan B. Flesche, Anna-Lena Forst, Jing Li, Jaakko Patrakka, Zhijie Xiao, Florian Grahammer, Et Al.

Open Access Publications

No abstract provided.


Oscar Is A Collagen Receptor That Costimulates Osteoclastogenesis In Dap12-Deficient Humans And Mice, Alexander David Barrow, Marina Cella, Marco Colonna, Nicolas Raynal, Thomas Levin Anderson, David A. Slatter, Dominique Bihan, Nicholas Pugh, Taesoo Kim, Jaerang Rho, Takako Nedishi-Koga, Jean-Marie Delaisse, Hiroshi Takayanagi, Joseph Lorenzo, Et Al. Jan 2011

Oscar Is A Collagen Receptor That Costimulates Osteoclastogenesis In Dap12-Deficient Humans And Mice, Alexander David Barrow, Marina Cella, Marco Colonna, Nicolas Raynal, Thomas Levin Anderson, David A. Slatter, Dominique Bihan, Nicholas Pugh, Taesoo Kim, Jaerang Rho, Takako Nedishi-Koga, Jean-Marie Delaisse, Hiroshi Takayanagi, Joseph Lorenzo, Et Al.

Open Access Publications

No abstract provided.


Arhgap24 Inactivates Rac1 In Mouse Podocytes, And A Mutant Form Is Associated With Familial Focal Segmental Glomerulosclerosis, Shreeram Akilesh, Hani Suleiman, Christine Stander, Haiyang Yu, Peter Lavin, Rasheed Gbadegesin, Corinne Antignac, Martin Pollack, Jeffrey B. Kopp, Michelle P. Winn, Andrey S. Shaw Jan 2011

Arhgap24 Inactivates Rac1 In Mouse Podocytes, And A Mutant Form Is Associated With Familial Focal Segmental Glomerulosclerosis, Shreeram Akilesh, Hani Suleiman, Christine Stander, Haiyang Yu, Peter Lavin, Rasheed Gbadegesin, Corinne Antignac, Martin Pollack, Jeffrey B. Kopp, Michelle P. Winn, Andrey S. Shaw

Open Access Publications

No abstract provided.


Pml-Rara Can Increase Hematopoietic Self-Renewal Without Causing A Myeloproliferative Disease In Mice, John S. Welch, Wenlin Yuan, Timothy J. Ley Jan 2011

Pml-Rara Can Increase Hematopoietic Self-Renewal Without Causing A Myeloproliferative Disease In Mice, John S. Welch, Wenlin Yuan, Timothy J. Ley

Open Access Publications

No abstract provided.


Dna Repair And Synthetic Lethality, Gong-She Guo, Feng-Mei Zhang, Rui-Jie Gao, Robert Delsite, Zhi-Hui Feng, Simon N. Powell Jan 2011

Dna Repair And Synthetic Lethality, Gong-She Guo, Feng-Mei Zhang, Rui-Jie Gao, Robert Delsite, Zhi-Hui Feng, Simon N. Powell

Open Access Publications

No abstract provided.


Micrornas, An Active And Versatile Group In Cancers, Jeffrey Liu, Min Zheng, Ya-Ling Tang, Xin-Hua Liang, Qin Yang Jan 2011

Micrornas, An Active And Versatile Group In Cancers, Jeffrey Liu, Min Zheng, Ya-Ling Tang, Xin-Hua Liang, Qin Yang

Open Access Publications

No abstract provided.


Molecular Determinants Of Human T-Lymphotropic Virus Type 1 Transmission And Spread, Michael D. Lairmore, Rajaneesh Anupam, Nadine Bowden, Robyn Haines, Rashade A. H. Hayness Ii, Lee Ratner, Patrick L. Green Jan 2011

Molecular Determinants Of Human T-Lymphotropic Virus Type 1 Transmission And Spread, Michael D. Lairmore, Rajaneesh Anupam, Nadine Bowden, Robyn Haines, Rashade A. H. Hayness Ii, Lee Ratner, Patrick L. Green

Open Access Publications

No abstract provided.


Genetic Basis For In Vivo Daptomycin Resistance In Enterococci, Elizabeth Lobos, Erica Sodergren, George M. Weinstock, Et Al Jan 2011

Genetic Basis For In Vivo Daptomycin Resistance In Enterococci, Elizabeth Lobos, Erica Sodergren, George M. Weinstock, Et Al

Open Access Publications

No abstract provided.


Complete Genome Sequence Of Treponema Paraluiscuniculi, Strain Cuniculi A: The Loss Of Infectivity To Humans Is Associated With Genome Decay, David Smajs, Marie Zobanikova, Michal Strouhal, Darina Cejkova, Shannon Dugan-Rocha, Petra Pospisilova, Steven J. Norris, Tom Albert, Xiang Qin, Kym Hallsworth-Pepin, Christian Buhay, Donna M. Muzny, Lei Chen, Richard A. Gibbs, George M. Weinstock Jan 2011

Complete Genome Sequence Of Treponema Paraluiscuniculi, Strain Cuniculi A: The Loss Of Infectivity To Humans Is Associated With Genome Decay, David Smajs, Marie Zobanikova, Michal Strouhal, Darina Cejkova, Shannon Dugan-Rocha, Petra Pospisilova, Steven J. Norris, Tom Albert, Xiang Qin, Kym Hallsworth-Pepin, Christian Buhay, Donna M. Muzny, Lei Chen, Richard A. Gibbs, George M. Weinstock

Open Access Publications

No abstract provided.


Binocular Disparity Tuning And Visual–Vestibular Congruency Of Multisensory Neurons In Macaque Parietal Cortex, Yun Yang, Sheng Liu, Syed A. Chowdhury, Gregory C. Deangelis, Dora E. Angelaki Jan 2011

Binocular Disparity Tuning And Visual–Vestibular Congruency Of Multisensory Neurons In Macaque Parietal Cortex, Yun Yang, Sheng Liu, Syed A. Chowdhury, Gregory C. Deangelis, Dora E. Angelaki

Open Access Publications

No abstract provided.


Host Type I Ifn Signals Are Required For Antitumor Cd8+ T Cell Responses Through Cd8Α+ Dendritic Cells, Mercedes B. Fuertes, Aalok K. Kacha, Justin Kline, Seng-Ryong Woo, David M. Kranz, Kenneth M. Murphy, Thomas F. Gajewski Jan 2011

Host Type I Ifn Signals Are Required For Antitumor Cd8+ T Cell Responses Through Cd8Α+ Dendritic Cells, Mercedes B. Fuertes, Aalok K. Kacha, Justin Kline, Seng-Ryong Woo, David M. Kranz, Kenneth M. Murphy, Thomas F. Gajewski

Open Access Publications

No abstract provided.


A Nine Amino Acid Domain Is Essential For Mutant Prion Protein Toxicity, Laura Westergard, Jessie A. Turnbaugh, David A. Harris Jan 2011

A Nine Amino Acid Domain Is Essential For Mutant Prion Protein Toxicity, Laura Westergard, Jessie A. Turnbaugh, David A. Harris

Open Access Publications

No abstract provided.


Multisensory Calibration Is Independent Of Cue Reliability, Adam Zaidel, Amanda H. Turner, Dora E. Angelaki Jan 2011

Multisensory Calibration Is Independent Of Cue Reliability, Adam Zaidel, Amanda H. Turner, Dora E. Angelaki

Open Access Publications

No abstract provided.


Short-Term Plasticity Optimizes Synaptic Information Transmission, Ziv Rotman, Pan-Yue Deng, Vitaly A. Klyachko Jan 2011

Short-Term Plasticity Optimizes Synaptic Information Transmission, Ziv Rotman, Pan-Yue Deng, Vitaly A. Klyachko

Open Access Publications

No abstract provided.


Stathmin Is Required For Stability Of The Drosophila Neuromuscular Junction, Ethan R. Graf, Heather M. Heerssen, Christina M. Wright, Graeme W. Davis, Aaron Diantonio Jan 2011

Stathmin Is Required For Stability Of The Drosophila Neuromuscular Junction, Ethan R. Graf, Heather M. Heerssen, Christina M. Wright, Graeme W. Davis, Aaron Diantonio

Open Access Publications

No abstract provided.